SIMILAR PATTERNS OF AMINO ACIDS FOR 1TYR_B_9CRB130_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cd1 CD1

(Mus musculus) 		PF07654
(C1-set)
PF16497
(MHC_I_3) 		4 LEU A 238
THR A 250
SER A 211
VAL A 207
 None
 0.98A 1tyrB-1cd1A:
0.2		 1tyrB-1cd1A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1chm CREATINE
AMIDINOHYDROLASE

(Pseudomonas
putida) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		4 LEU A 265
THR A 220
LEU A 246
SER A 224
 None
 0.99A 1tyrB-1chmA:
0.0		 1tyrB-1chmA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ey2 HOMOGENTISATE
1,2-DIOXYGENASE

(Homo sapiens) 		PF04209
(HgmA) 		4 LEU A 364
THR A 118
LEU A  95
SER A 416
 None
 0.91A 1tyrB-1ey2A:
0.0		 1tyrB-1ey2A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fml RETINOL DEHYDRATASE

(Spodoptera
frugiperda) 		PF00685
(Sulfotransfer_1) 		4 LEU A 246
LEU A 183
SER A  70
VAL A  66
 None
None
A3P  A 400 ( 4.5A)
None
 0.88A 1tyrB-1fmlA:
undetectable		 1tyrB-1fmlA:
15.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		4 LEU A  17
ALA A 108
LEU A 110
SER A 117
 None
 0.64A 1tyrB-1gkeA:
20.5		 1tyrB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		5 LEU A  17
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.35A 1tyrB-1gkeA:
20.5		 1tyrB-1gkeA:
83.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gke TRANSTHYRETIN

(Rattus
norvegicus) 		PF00576
(Transthyretin) 		4 LYS A  15
THR A 106
ALA A 108
VAL A 121
 None
 0.45A 1tyrB-1gkeA:
20.5		 1tyrB-1gkeA:
83.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gut MOLYBDATE BINDING
PROTEIN II

(Clostridium
pasteurianum) 		PF03459
(TOBE) 		4 LYS A  18
LEU A  16
ALA A  23
SER A  37
 None
 0.66A 1tyrB-1gutA:
undetectable		 1tyrB-1gutA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1no7 MAJOR CAPSID PROTEIN

(Human
alphaherpesvirus
1) 		PF03122
(Herpes_MCP) 		4 LEU A 994
THR A 905
LEU A 909
SER A 757
 None
 0.98A 1tyrB-1no7A:
undetectable		 1tyrB-1no7A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1no7 MAJOR CAPSID PROTEIN

(Human
alphaherpesvirus
1) 		PF03122
(Herpes_MCP) 		4 THR A 905
ALA A 907
LEU A 909
SER A 757
 None
 0.99A 1tyrB-1no7A:
undetectable		 1tyrB-1no7A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvx PROTEIN
(ENDO-1,4-BETA-XYLAN
ASE)

(Byssochlamys
spectabilis) 		PF00457
(Glyco_hydro_11) 		4 LEU A 105
LEU A 117
SER A 139
VAL A  85
 None
 0.92A 1tyrB-1pvxA:
0.0		 1tyrB-1pvxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb3 4-HYDROXYBENZOYL-COA
REDUCTASE BETA
SUBUNIT

(Thauera
aromatica) 		PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C) 		4 LEU B 252
ALA B 240
LEU B 242
SER B 219
 None
 0.88A 1tyrB-1sb3B:
0.0		 1tyrB-1sb3B:
16.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		6 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
VAL A 121
 None
 0.56A 1tyrB-1sn2A:
20.0		 1tyrB-1sn2A:
54.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t4n RIBONUCLEASE III

(Saccharomyces
cerevisiae) 		PF00035
(dsrm) 		4 LYS A 443
ALA A 446
LEU A 377
SER A 376
 None
 0.87A 1tyrB-1t4nA:
undetectable		 1tyrB-1t4nA:
22.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		7 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
SER A 117
VAL A 121
 None
 0.62A 1tyrB-1tfpA:
18.0		 1tyrB-1tfpA:
73.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txk GLUCANS BIOSYNTHESIS
PROTEIN G

(Escherichia
coli) 		PF04349
(MdoG) 		4 ALA A 335
LEU A 312
SER A 274
VAL A 159
 None
 0.98A 1tyrB-1txkA:
undetectable		 1tyrB-1txkA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhl SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY MEMBER
(5L265), PUTATIVE
TROPINONE
REDUCTASE-II

(Caenorhabditis
elegans) 		PF13561
(adh_short_C2) 		4 LEU A  90
THR A  36
SER A   8
VAL A  63
 None
 0.63A 1tyrB-1xhlA:
undetectable		 1tyrB-1xhlA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8p [PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 3

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		4 LEU A 281
THR A 272
LEU A 276
VAL A 220
 None
 0.51A 1tyrB-1y8pA:
undetectable		 1tyrB-1y8pA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yna ENDO-1,4-BETA-XYLANA
SE

(Thermomyces
lanuginosus) 		PF00457
(Glyco_hydro_11) 		4 LEU A 105
LEU A 117
SER A 139
VAL A  85
 None
 0.93A 1tyrB-1ynaA:
undetectable		 1tyrB-1ynaA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zno HYPOTHETICAL UPF0244
PROTEIN VC0702

(Vibrio cholerae) 		PF01931
(NTPase_I-T) 		4 LEU A  84
THR A  93
ALA A  95
SER A 108
 None
 0.90A 1tyrB-1znoA:
undetectable		 1tyrB-1znoA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdw HYPOTHETICAL PROTEIN
K11E8.1D

(Caenorhabditis
elegans) 		PF00069
(Pkinase) 		4 THR A 305
ALA A 309
LEU A 313
SER A 314
 None
 0.96A 1tyrB-2bdwA:
undetectable		 1tyrB-2bdwA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7b OBSCURIN

(Homo sapiens) 		PF07679
(I-set) 		4 LEU A  18
THR A  87
ALA A  89
LEU A  91
 None
 0.86A 1tyrB-2e7bA:
undetectable		 1tyrB-2e7bA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f3j RNA AND EXPORT
FACTOR BINDING
PROTEIN 2

(Mus musculus) 		PF00076
(RRM_1)
PF07078
(FYTT) 		4 LEU A 149
THR A  73
ALA A  75
LEU A  77
 None
 0.82A 1tyrB-2f3jA:
undetectable		 1tyrB-2f3jA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fd5 TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF00440
(TetR_N) 		4 LEU A  73
LEU A  77
SER A  78
VAL A 179
 None
 0.75A 1tyrB-2fd5A:
undetectable		 1tyrB-2fd5A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h4u THIOESTERASE
SUPERFAMILY MEMBER 2

(Homo sapiens) 		PF03061
(4HBT) 		4 LYS A 136
THR A 116
ALA A 114
VAL A 106
 None
 0.77A 1tyrB-2h4uA:
undetectable		 1tyrB-2h4uA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ill TITIN

(Homo sapiens) 		PF07679
(I-set) 		4 LEU A  12
ALA A  90
LEU A  92
VAL A  77
 None
 0.83A 1tyrB-2illA:
undetectable		 1tyrB-2illA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iq1 PROTEIN PHOSPHATASE
2C KAPPA, PPM1K

(Homo sapiens) 		PF00481
(PP2C) 		4 LEU A 201
THR A 191
LEU A 195
VAL A 125
 None
 0.67A 1tyrB-2iq1A:
undetectable		 1tyrB-2iq1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iyo 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Lactococcus
lactis) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 LEU A 205
THR A 236
LEU A 211
SER A 212
 None
 0.88A 1tyrB-2iyoA:
undetectable		 1tyrB-2iyoA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mpr MALTOPORIN

(Salmonella
enterica) 		PF02264
(LamB) 		4 LEU A  44
THR A  40
ALA A  42
VAL A  68
 None
 0.94A 1tyrB-2mprA:
undetectable		 1tyrB-2mprA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obx 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE
1

(Mesorhizobium
loti) 		PF00885
(DMRL_synthase) 		4 LEU A 111
ALA A  73
LEU A  75
VAL A  12
 None
 0.71A 1tyrB-2obxA:
undetectable		 1tyrB-2obxA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogv MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR
PRECURSOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A 649
THR A 654
ALA A 652
VAL A 659
 None
 0.97A 1tyrB-2ogvA:
undetectable		 1tyrB-2ogvA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qv3 VACUOLATING
CYTOTOXIN

(Helicobacter
pylori) 		PF02691
(VacA) 		4 THR A 641
LEU A 645
SER A 624
VAL A 620
 None
 0.70A 1tyrB-2qv3A:
undetectable		 1tyrB-2qv3A:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uv8 FATTY ACID SYNTHASE
SUBUNIT BETA (FAS1)

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF01575
(MaoC_dehydratas)
PF08354
(DUF1729)
PF13452
(MaoC_dehydrat_N)
PF16073
(SAT) 		4 LYS G1358
THR G1407
SER G1397
VAL G1393
 None
 0.78A 1tyrB-2uv8G:
undetectable		 1tyrB-2uv8G:
5.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7g UROCANATE HYDRATASE

(Pseudomonas
putida) 		PF01175
(Urocanase)
PF17391
(Urocanase_N)
PF17392
(Urocanase_C) 		4 LEU A 171
THR A 265
ALA A 173
LEU A 194
 None
NAD  A3001 (-4.2A)
NAD  A3001 ( 4.4A)
None
 1.00A 1tyrB-2v7gA:
undetectable		 1tyrB-2v7gA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9t SLIT HOMOLOG 2
PROTEIN N-PRODUCT

(Homo sapiens) 		PF01462
(LRRNT)
PF01463
(LRRCT)
PF13855
(LRR_8) 		4 LEU B 363
THR B 415
ALA B 391
LEU B 367
 None
 0.87A 1tyrB-2v9tB:
undetectable		 1tyrB-2v9tB:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wfd LEUCYL-TRNA
SYNTHETASE,
CYTOPLASMIC

(Homo sapiens) 		PF00133
(tRNA-synt_1) 		4 LEU A 269
THR A 293
ALA A 291
LEU A 289
 None
 0.89A 1tyrB-2wfdA:
undetectable		 1tyrB-2wfdA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xd4 PHOSPHORIBOSYLAMINE-
-GLYCINE LIGASE

(Bacillus
subtilis) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		4 THR A 353
ALA A 351
LEU A 349
SER A 348
 None
 0.96A 1tyrB-2xd4A:
undetectable		 1tyrB-2xd4A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyg 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Klebsiella
pneumoniae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 LEU A 204
THR A 235
LEU A 210
SER A 211
 None
 0.83A 1tyrB-2zygA:
undetectable		 1tyrB-2zygA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdw NKG2-A/NKG2-B TYPE
II INTEGRAL MEMBRANE
PROTEIN

(Homo sapiens) 		PF00059
(Lectin_C) 		4 LEU B 216
ALA B 209
LEU B 211
SER B 173
 None
 0.84A 1tyrB-3bdwB:
undetectable		 1tyrB-3bdwB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdw NKG2-A/NKG2-B TYPE
II INTEGRAL MEMBRANE
PROTEIN

(Homo sapiens) 		PF00059
(Lectin_C) 		4 LEU B 216
THR B 188
LEU B 211
SER B 173
 None
 0.99A 1tyrB-3bdwB:
undetectable		 1tyrB-3bdwB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cyj MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Rubrobacter
xylanophilus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 THR A  32
LEU A  36
SER A  12
VAL A  16
 None
 0.76A 1tyrB-3cyjA:
undetectable		 1tyrB-3cyjA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eeq PUTATIVE COBALAMIN
BIOSYNTHESIS PROTEIN
G HOMOLOG

(Sulfolobus
solfataricus) 		PF01890
(CbiG_C)
PF11760
(CbiG_N) 		4 LEU A 316
THR A 328
ALA A 330
SER A 217
 None
SO4  A   3 (-3.1A)
None
None
 0.79A 1tyrB-3eeqA:
undetectable		 1tyrB-3eeqA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3euh CHROMOSOME PARTITION
PROTEIN MUKF
MUKE

(Escherichia
coli) 		PF03882
(KicB)
PF04288
(MukE)
PF17192
(MukF_M)
PF17193
(MukF_C) 		4 LEU A 315
LEU C  97
SER C  98
VAL A 305
 None
 0.78A 1tyrB-3euhA:
undetectable		 1tyrB-3euhA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f5o THIOESTERASE
SUPERFAMILY MEMBER 2

(Homo sapiens) 		PF03061
(4HBT) 		4 LYS A 136
THR A 116
ALA A 114
VAL A 106
 UOC  A 149 (-3.1A)
None
None
None
 0.83A 1tyrB-3f5oA:
undetectable		 1tyrB-3f5oA:
21.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		4 LYS A  15
LEU A  17
LEU A 110
SER A 117
 IFA  A3000 (-3.0A)
IFA  A3000 ( 4.7A)
IFA  A3000 (-4.1A)
IFA  A3000 (-3.9A)
 0.71A 1tyrB-3fc8A:
21.5		 1tyrB-3fc8A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3fc8 TRANSTHYRETIN

(Homo sapiens) 		PF00576
(Transthyretin) 		6 LYS A  15
LEU A  17
THR A 106
ALA A 108
LEU A 110
VAL A 121
 IFA  A3000 (-3.0A)
IFA  A3000 ( 4.7A)
IFA  A3000 (-4.9A)
IFA  A3000 (-3.1A)
IFA  A3000 (-4.1A)
None
 0.48A 1tyrB-3fc8A:
21.5		 1tyrB-3fc8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h8f CYTOSOL
AMINOPEPTIDASE

(Pseudomonas
putida) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 THR A  15
ALA A  70
LEU A  65
VAL A  13
 None
 1.00A 1tyrB-3h8fA:
undetectable		 1tyrB-3h8fA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kzu 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
SYNTHASE II

(Brucella
melitensis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 THR A 409
ALA A 411
LEU A 413
SER A 401
 None
 0.73A 1tyrB-3kzuA:
undetectable		 1tyrB-3kzuA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m88 AMOEBIASIN-2

(Entamoeba
histolytica) 		PF09394
(Inhibitor_I42) 		4 LEU A 100
THR A  96
LEU A 116
VAL A 120
 None
 0.81A 1tyrB-3m88A:
undetectable		 1tyrB-3m88A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwg MICROCOMPARTMENTS
PROTEIN

(Desulfitobacterium
hafniense) 		PF00936
(BMC) 		4 LEU A  44
LEU A  31
SER A  85
VAL A 137
 None
 1.00A 1tyrB-3nwgA:
undetectable		 1tyrB-3nwgA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oit OS07G0271500 PROTEIN

(Oryza sativa) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 LEU A 203
ALA A 201
SER A 351
VAL A 139
 None
 0.86A 1tyrB-3oitA:
undetectable		 1tyrB-3oitA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9n POSSIBLE
METHYLTRANSFERASE
(METHYLASE)

(Mycobacterium
tuberculosis) 		PF03602
(Cons_hypoth95) 		4 LEU A  89
LEU A  91
SER A  92
VAL A  47
 None
 0.90A 1tyrB-3p9nA:
undetectable		 1tyrB-3p9nA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qi6 CYSTATHIONINE
GAMMA-SYNTHASE METB
(CGS)

(Mycobacterium
ulcerans) 		PF01053
(Cys_Met_Meta_PP) 		4 LEU A 203
THR A 207
LEU A 221
VAL A 217
 None
LLP  A 208 (-3.4A)
None
LLP  A 208 ( 4.9A)
 0.96A 1tyrB-3qi6A:
undetectable		 1tyrB-3qi6A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3si9 DIHYDRODIPICOLINATE
SYNTHASE

(Bartonella
henselae) 		PF00701
(DHDPS) 		4 LEU A 264
ALA A 260
LEU A 266
VAL A 248
 None
 0.80A 1tyrB-3si9A:
undetectable		 1tyrB-3si9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty1 HYPOTHETICAL ALDOSE
1-EPIMERASE

(Klebsiella
pneumoniae) 		PF14486
(DUF4432) 		4 LEU A 210
THR A 195
LEU A 199
VAL A 183
 None
 0.84A 1tyrB-3ty1A:
undetectable		 1tyrB-3ty1A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vk9 GLUTATHIONE
S-TRANSFERASE DELTA

(Bombyx mori) 		PF13417
(GST_N_3)
PF14497
(GST_C_3) 		4 THR A  20
ALA A  16
SER A 164
VAL A 156
 None
 0.70A 1tyrB-3vk9A:
undetectable		 1tyrB-3vk9A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bva THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE

(Mus musculus) 		PF02423
(OCD_Mu_crystall) 		4 LEU A 138
ALA A 197
SER A 135
VAL A 216
 None
 0.90A 1tyrB-4bvaA:
undetectable		 1tyrB-4bvaA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c5f MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE C

(Escherichia
coli) 		PF01464
(SLT)
PF11873
(DUF3393) 		4 LEU A 277
THR A 240
LEU A 274
VAL A 237
 None
 0.92A 1tyrB-4c5fA:
undetectable		 1tyrB-4c5fA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dmg PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493

(Thermus
thermophilus) 		PF02475
(Met_10) 		4 LEU A 259
ALA A 255
LEU A 261
VAL A 225
 None
 0.95A 1tyrB-4dmgA:
undetectable		 1tyrB-4dmgA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dmo N-HYDROXYARYLAMINE
O-ACETYLTRANSFERASE

(Bacillus cereus) 		PF00797
(Acetyltransf_2) 		4 LEU A 233
THR A 221
ALA A 226
LEU A 228
 None
 0.96A 1tyrB-4dmoA:
undetectable		 1tyrB-4dmoA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2n D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE,
NAD-BINDING

(Polaromonas sp.
JS666) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 THR A  76
ALA A  78
LEU A  80
VAL A  53
 None
 0.62A 1tyrB-4g2nA:
undetectable		 1tyrB-4g2nA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gb7 6-AMINOHEXANOATE-DIM
ER HYDROLASE

(Bacillus
anthracis) 		PF00144
(Beta-lactamase) 		4 LEU A 215
THR A  61
LEU A 210
VAL A 287
 None
 0.98A 1tyrB-4gb7A:
undetectable		 1tyrB-4gb7A:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k24 ANTI-UPAR ANTIBODY,
HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU H 124
THR H 176
SER H 180
VAL H 169
 None
 0.96A 1tyrB-4k24H:
undetectable		 1tyrB-4k24H:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knc ALGINATE
BIOSYNTHESIS PROTEIN
ALGX

(Pseudomonas
aeruginosa) 		no annotation 4 LEU B 107
THR B 192
LEU B 320
VAL B 189
 None
 0.95A 1tyrB-4kncB:
undetectable		 1tyrB-4kncB:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq8 CYTOCHROME P450 19A1

(Homo sapiens) 		PF00067
(p450) 		4 LEU A 372
THR A  94
SER A  98
VAL A  87
 None
 0.74A 1tyrB-4kq8A:
undetectable		 1tyrB-4kq8A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1y SALIVARY NITROPHORIN

(Cimex
lectularius) 		no annotation 4 LEU A  86
ALA A  41
SER A  13
VAL A   9
 None
 0.80A 1tyrB-4l1yA:
undetectable		 1tyrB-4l1yA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l3w LIPASE

(Rhizopus
microsporus) 		PF01764
(Lipase_3) 		4 THR A 123
ALA A 137
SER A 142
VAL A 121
 None
 0.83A 1tyrB-4l3wA:
undetectable		 1tyrB-4l3wA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mio INOSITOL
2-DEHYDROGENASE/D-CH
IRO-INOSITOL
3-DEHYDROGENASE

(Lactobacillus
casei) 		PF01408
(GFO_IDH_MocA) 		4 LEU A 213
LEU A 227
SER A 154
VAL A 150
 None
None
GOL  A 402 (-2.8A)
None
 0.91A 1tyrB-4mioA:
undetectable		 1tyrB-4mioA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nec PUTATIVE
SAM-DEPENDENT
METHYLTRANSFERASE

(Streptomyces
lasaliensis) 		PF13649
(Methyltransf_25) 		4 LEU A 218
THR A 107
LEU A 142
SER A 111
 None
None
None
SAH  A 401 (-3.3A)
 0.86A 1tyrB-4necA:
undetectable		 1tyrB-4necA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nen INTEGRIN BETA-2

(Homo sapiens) 		PF00362
(Integrin_beta)
PF07965
(Integrin_B_tail)
PF17205
(PSI_integrin) 		4 THR B  65
ALA B  63
SER B  61
VAL B  81
 None
 0.87A 1tyrB-4nenB:
undetectable		 1tyrB-4nenB:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nvr PUTATIVE
ACYLTRANSFERASE

(Salmonella
enterica) 		PF00561
(Abhydrolase_1) 		4 LEU A 278
THR A 137
SER A 283
VAL A 113
 None
 0.93A 1tyrB-4nvrA:
undetectable		 1tyrB-4nvrA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4opw UNCHARACTERIZED
PROTEIN

(Parabacteroides
merdae) 		PF10988
(DUF2807) 		4 LEU A 166
ALA A 188
LEU A 151
VAL A 211
 None
 0.88A 1tyrB-4opwA:
undetectable		 1tyrB-4opwA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0e MAF-LIKE PROTEIN
YHDE

(Escherichia
coli) 		PF02545
(Maf) 		4 LEU A  67
THR A 105
LEU A 109
VAL A 120
 None
 0.71A 1tyrB-4p0eA:
undetectable		 1tyrB-4p0eA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		4 LEU A 430
THR A 422
LEU A 407
VAL A 418
 NPS  A 601 ( 4.0A)
None
NPS  A 601 ( 4.9A)
None
 0.88A 1tyrB-4po0A:
undetectable		 1tyrB-4po0A:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjk ACETOLACTATE
SYNTHASE

(Bacillus
subtilis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A 325
THR A 304
LEU A 308
VAL A 281
 None
 0.63A 1tyrB-4rjkA:
undetectable		 1tyrB-4rjkA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rle UNCHARACTERIZED
PROTEIN YAAQ

(Bacillus
subtilis) 		PF06153
(CdAMP_rec) 		4 LEU A 101
THR A  97
LEU A   3
VAL A   7
 None
 0.96A 1tyrB-4rleA:
undetectable		 1tyrB-4rleA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1r ALPHA-1,6-MANNANASE

(Bacteroides
thetaiotaomicron) 		PF03663
(Glyco_hydro_76) 		4 THR A 202
ALA A 206
LEU A 210
SER A 211
 None
 0.86A 1tyrB-4v1rA:
undetectable		 1tyrB-4v1rA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zv9 UNCHARACTERIZED
PROTEIN

(Escherichia
coli) 		PF01738
(DLH) 		4 LYS A  90
LEU A  88
THR A  98
LEU A 129
 None
 1.00A 1tyrB-4zv9A:
undetectable		 1tyrB-4zv9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6s INTEGRIN BETA-2

(Homo sapiens) 		PF00362
(Integrin_beta)
PF17205
(PSI_integrin) 		4 THR B  65
ALA B  63
SER B  61
VAL B  81
 None
 0.99A 1tyrB-5e6sB:
undetectable		 1tyrB-5e6sB:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6w INTEGRIN BETA-2

(Homo sapiens) 		PF17205
(PSI_integrin) 		4 THR A  65
ALA A  63
SER A  61
VAL A  81
 None
 0.98A 1tyrB-5e6wA:
undetectable		 1tyrB-5e6wA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5equ SNON,SNON

(Streptomyces
nogalater) 		PF05721
(PhyH) 		4 LEU A 108
THR A 227
ALA A 229
VAL A 149
 None
 0.63A 1tyrB-5equA:
undetectable		 1tyrB-5equA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ere EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Desulfohalobium
retbaense) 		PF13458
(Peripla_BP_6) 		4 LEU A 511
THR A 591
ALA A 589
SER A 578
 None
 0.83A 1tyrB-5ereA:
undetectable		 1tyrB-5ereA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7c ALPHA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 LEU A  69
THR A  79
LEU A  83
VAL A 285
 None
 0.80A 1tyrB-5f7cA:
undetectable		 1tyrB-5f7cA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fku DNA POLYMERASE III
SUBUNIT ALPHA

(Escherichia
coli) 		PF01336
(tRNA_anti-codon)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		4 THR A 995
ALA A 997
LEU A 999
VAL A1050
 None
 0.97A 1tyrB-5fkuA:
undetectable		 1tyrB-5fkuA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gt5 PECTATE LYASE

(Paenibacillus
sp. 0602) 		no annotation 4 LEU A 224
LEU A 231
SER A 232
VAL A 204
 None
 0.93A 1tyrB-5gt5A:
undetectable		 1tyrB-5gt5A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h68 CHROMOSOME PARTITION
PROTEIN SMC

(Geobacillus
stearothermophilus) 		PF02463
(SMC_N) 		4 LEU A1086
LEU A1089
SER A1090
VAL A 146
 None
 0.96A 1tyrB-5h68A:
undetectable		 1tyrB-5h68A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koh NITROGENASE FEMO
BETA SUBUNIT PROTEIN
NIFK

(Gluconacetobacter
diazotrophicus) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		4 LEU B 454
THR B 484
LEU B 437
VAL B 481
 None
 0.91A 1tyrB-5kohB:
undetectable		 1tyrB-5kohB:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lj6 MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Aggregatibacter
actinomycetemcomitans) 		no annotation 4 LEU A 448
ALA A 364
LEU A 366
SER A 350
 None
 0.52A 1tyrB-5lj6A:
undetectable		 1tyrB-5lj6A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		no annotation 4 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.90A 1tyrB-5n48A:
undetectable		 1tyrB-5n48A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nkn NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN

(Homo sapiens) 		no annotation 4 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
LOC  A 201 (-3.5A)
None
None
 0.93A 1tyrB-5nknA:
undetectable		 1tyrB-5nknA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nnp PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 LEU C  96
LEU C  98
SER C  99
VAL C  84
 None
 0.97A 1tyrB-5nnpC:
undetectable		 1tyrB-5nnpC:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ori ALBUMIN

(Capra hircus) 		no annotation 4 LEU A 429
THR A 421
LEU A 406
VAL A 417
 None
 0.80A 1tyrB-5oriA:
undetectable		 1tyrB-5oriA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vfr PROTEASOME SUBUNIT
ALPHA TYPE-6

(Homo sapiens) 		no annotation 4 THR G 194
ALA G 198
LEU G 202
SER G 203
 None
 0.78A 1tyrB-5vfrG:
undetectable		 1tyrB-5vfrG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w6l RTX
REPEAT-CONTAINING
CYTOTOXIN

(Vibrio
vulnificus) 		no annotation 4 ALA A3956
LEU A3954
SER A3951
VAL A3798
 ALA  A3956 ( 0.0A)
LEU  A3954 ( 0.6A)
SER  A3951 ( 0.0A)
VAL  A3798 ( 0.6A)
 0.99A 1tyrB-5w6lA:
undetectable		 1tyrB-5w6lA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w81 CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR

(Danio rerio) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF14396
(CFTR_R) 		4 LEU A 601
ALA A 572
LEU A 570
SER A 490
 None
 0.85A 1tyrB-5w81A:
undetectable		 1tyrB-5w81A:
6.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wsl KERATINASE

(Meiothermus
taiwanensis) 		no annotation 4 THR A 152
ALA A 154
SER A 130
VAL A 126
 None
 0.67A 1tyrB-5wslA:
undetectable		 1tyrB-5wslA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis) 		PF00318
(Ribosomal_S2) 		4 LYS A  14
LEU A 175
ALA A  18
SER A 168
 None
 0.90A 1tyrB-5xyiA:
undetectable		 1tyrB-5xyiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yiv CELL CYCLE
REGULATORY PROTEIN
GCRA

(Caulobacter
vibrioides) 		no annotation 4 LEU A  14
LEU A  19
SER A  20
VAL A  31
 None
 0.99A 1tyrB-5yivA:
undetectable		 1tyrB-5yivA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT B

(Flavobacterium
johnsoniae) 		no annotation 5 LEU B 519
ALA B  96
LEU B 470
SER B 469
VAL B 110
 None
 1.32A 1tyrB-6btmB:
undetectable		 1tyrB-6btmB:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6egt GLYCOPROTEIN

(Rift Valley
fever
phlebovirus) 		no annotation 4 LEU A1011
THR A 883
LEU A 890
SER A 879
 None
 1.00A 1tyrB-6egtA:
undetectable		 1tyrB-6egtA:
14.52