SIMILAR PATTERNS OF AMINO ACIDS FOR 1TV8_A_SAMA1501_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dbv GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE


(Geobacillus
stearothermophilus)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
4 THR O 179
GLU O 314
SER O 238
VAL O 240
SO4  O 338 (-3.5A)
None
None
None
1.01A 1tv8A-1dbvO:
undetectable
1tv8A-1dbvO:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I GAMMA
SUBUNIT


(Methanopyrus
kandleri)
PF02240
(MCR_gamma)
4 TYR C 190
SER C 152
VAL C 154
MET C  44
None
1.17A 1tv8A-1e6vC:
undetectable
1tv8A-1e6vC:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e8t HEMAGGLUTININ-NEURAM
INIDASE


(Avian
avulavirus 1)
PF00423
(HN)
4 THR A 471
THR A 527
SER A 544
VAL A 563
None
1.10A 1tv8A-1e8tA:
undetectable
1tv8A-1e8tA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1epx FRUCTOSE-1,6-BISPHOS
PHATE ALDOLASE


(Leishmania
mexicana)
PF00274
(Glycolytic)
4 TYR A 161
THR A 265
THR A 269
VAL A 173
None
1.23A 1tv8A-1epxA:
2.8
1tv8A-1epxA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fft UBIQUINOL OXIDASE

(Escherichia
coli)
PF00115
(COX1)
4 THR A 204
THR A 201
SER A 197
VAL A 153
None
1.18A 1tv8A-1fftA:
undetectable
1tv8A-1fftA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gh6 LARGE T ANTIGEN
RETINOBLASTOMA-ASSOC
IATED PROTEIN


(Macaca mulatta
polyomavirus 1;
Homo sapiens)
no annotation
PF01857
(RB_B)
PF01858
(RB_A)
4 TYR B 709
THR A  81
GLU A 101
SER A 106
None
1.21A 1tv8A-1gh6B:
undetectable
1tv8A-1gh6B:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1goj KINESIN HEAVY CHAIN

(Neurospora
crassa)
PF00225
(Kinesin)
4 TYR A 282
THR A  83
THR A 301
VAL A 268
None
1.23A 1tv8A-1gojA:
undetectable
1tv8A-1gojA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h5q NADP-DEPENDENT
MANNITOL
DEHYDROGENASE


(Agaricus
bisporus)
PF13561
(adh_short_C2)
4 TYR A 169
THR A 207
THR A 204
MET A 150
NAP  A 263 (-4.4A)
None
NAP  A 263 ( 3.9A)
None
1.15A 1tv8A-1h5qA:
2.5
1tv8A-1h5qA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i5p PESTICIDIAL CRYSTAL
PROTEIN CRY2AA


(Bacillus
thuringiensis)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
PF09131
(Endotoxin_mid)
4 TYR A 255
THR A  97
VAL A  57
MET A 183
None
1.03A 1tv8A-1i5pA:
undetectable
1tv8A-1i5pA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jof CARBOXY-CIS,CIS-MUCO
NATE CYCLASE


(Neurospora
crassa)
PF10282
(Lactonase)
4 THR A 306
GLU A 335
THR A 304
VAL A 259
None
1.12A 1tv8A-1jofA:
undetectable
1tv8A-1jofA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rpw TRANSCRIPTIONAL
REGULATOR QACR


(Staphylococcus
aureus)
PF00440
(TetR_N)
PF08360
(TetR_C_5)
4 TYR A 127
GLU A  68
THR A  89
VAL A 156
None
1.00A 1tv8A-1rpwA:
undetectable
1tv8A-1rpwA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrh SEED LIPOXYGENASE-3

(Glycine max)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
4 THR A 575
THR A 728
SER A 510
VAL A 372
None
1.16A 1tv8A-1rrhA:
undetectable
1tv8A-1rrhA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ser PROTEIN (SERYL-TRNA
SYNTHETASE
(E.C.6.1.1.11))


(Thermus
thermophilus)
PF00587
(tRNA-synt_2b)
PF02403
(Seryl_tRNA_N)
4 THR A 380
GLU A 227
SER A 350
VAL A 318
None
1.18A 1tv8A-1serA:
undetectable
1tv8A-1serA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5c CENTROMERIC PROTEIN
E


(Homo sapiens)
PF00225
(Kinesin)
4 TYR A 283
THR A  81
THR A 302
VAL A 268
None
1.02A 1tv8A-1t5cA:
undetectable
1tv8A-1t5cA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tt7 YHFP

(Bacillus
subtilis)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 THR A 134
THR A 130
SER A  91
VAL A  96
None
1.10A 1tv8A-1tt7A:
undetectable
1tv8A-1tt7A:
22.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tv8 MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A


(Staphylococcus
aureus)
PF04055
(Radical_SAM)
PF06463
(Mob_synth_C)
PF13394
(Fer4_14)
7 TYR A  30
THR A  73
GLU A  76
THR A 102
SER A 126
VAL A 167
MET A 197
SAM  A1501 ( 4.5A)
SAM  A1501 (-4.0A)
SAM  A1501 (-4.4A)
SAM  A1501 (-4.3A)
SAM  A1501 ( 2.4A)
SAM  A1501 (-4.5A)
DTU  A1502 (-4.2A)
0.00A 1tv8A-1tv8A:
55.3
1tv8A-1tv8A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ve4 ATP
PHOSPHORIBOSYLTRANSF
ERASE


(Thermus
thermophilus)
PF01634
(HisG)
4 TYR A 115
GLU A  85
SER A 175
VAL A 154
None
1.15A 1tv8A-1ve4A:
undetectable
1tv8A-1ve4A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w7c LYSYL OXIDASE

(Komagataella
pastoris)
PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF09248
(DUF1965)
4 THR A 423
GLU A 340
SER A  63
VAL A  69
NAG  A1786 (-3.0A)
None
MG  A 804 ( 4.0A)
None
1.20A 1tv8A-1w7cA:
undetectable
1tv8A-1w7cA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcx UROPORPHYRINOGEN III
SYNTHASE


(Thermus
thermophilus)
PF02602
(HEM4)
4 TYR A  49
THR A  66
THR A  67
VAL A  44
None
0.94A 1tv8A-1wcxA:
undetectable
1tv8A-1wcxA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z8y SPIKE GLYCOPROTEIN
E1


(Sindbis virus)
PF01589
(Alpha_E1_glycop)
4 THR A 141
THR A 140
SER A 156
VAL A 161
None
1.21A 1tv8A-1z8yA:
undetectable
1tv8A-1z8yA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbs HYPOTHETICAL PROTEIN
PG1100


(Porphyromonas
gingivalis)
PF01869
(BcrAD_BadFG)
4 THR A  28
THR A  12
VAL A  94
MET A  77
None
0.89A 1tv8A-1zbsA:
undetectable
1tv8A-1zbsA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aml SIS DOMAIN PROTEIN

(Listeria
monocytogenes)
PF01380
(SIS)
4 TYR A 360
THR A  99
GLU A 126
SER A  95
None
None
None
PO4  A 362 (-2.9A)
1.23A 1tv8A-2amlA:
undetectable
1tv8A-2amlA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3x IRON-RESPONSIVE
ELEMENT BINDING
PROTEIN 1


(Homo sapiens)
PF00330
(Aconitase)
PF00694
(Aconitase_C)
4 TYR A 560
THR A 256
THR A 258
VAL A 531
None
1.19A 1tv8A-2b3xA:
undetectable
1tv8A-2b3xA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cw6 HYDROXYMETHYLGLUTARY
L-COA LYASE,
MITOCHONDRIAL


(Homo sapiens)
PF00682
(HMGL-like)
4 THR A 322
SER A 316
VAL A 260
MET A  62
None
1.11A 1tv8A-2cw6A:
4.9
1tv8A-2cw6A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8q ALKALINE
THERMOSTABLE
ENDOXYLANASE


(Bacillus sp.
NG-27)
PF00331
(Glyco_hydro_10)
4 TYR A  42
THR A 318
GLU A  48
VAL A  37
None
1.19A 1tv8A-2f8qA:
6.6
1tv8A-2f8qA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN


(Corynebacterium
diphtheriae)
PF00994
(MoCF_biosynth)
4 THR A  84
GLU A  50
THR A  76
SER A 138
None
None
NA  A 301 (-3.3A)
NA  A 301 (-3.6A)
1.20A 1tv8A-2g2cA:
undetectable
1tv8A-2g2cA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggq 401AA LONG
HYPOTHETICAL
GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E


(Sulfurisphaera
tokodaii)
PF00132
(Hexapep)
PF00483
(NTP_transferase)
4 THR A 365
THR A 327
SER A 310
VAL A 295
None
0.97A 1tv8A-2ggqA:
2.3
1tv8A-2ggqA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hb6 LEUCINE
AMINOPEPTIDASE 1


(Caenorhabditis
elegans)
PF00883
(Peptidase_M17)
4 TYR A 471
THR A 364
SER A 371
VAL A 400
None
1.21A 1tv8A-2hb6A:
undetectable
1tv8A-2hb6A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6l ALDEHYDE
DEHYDROGENASE FAMILY
7 MEMBER A1


(Homo sapiens)
PF00171
(Aldedh)
4 TYR A 489
THR A 165
VAL A 161
MET A 182
None
1.13A 1tv8A-2j6lA:
undetectable
1tv8A-2j6lA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7c BETA-GLUCOSIDASE A

(Thermotoga
maritima)
PF00232
(Glyco_hydro_1)
4 TYR A 435
GLU A 351
THR A  16
VAL A  73
None
IDE  A1446 (-2.5A)
None
None
1.19A 1tv8A-2j7cA:
7.3
1tv8A-2j7cA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pft EXOCYTOSIS PROTEIN

(Mus musculus)
PF03081
(Exo70)
4 TYR A 282
THR A 437
GLU A 387
VAL A 286
None
1.15A 1tv8A-2pftA:
undetectable
1tv8A-2pftA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ph1 NUCLEOTIDE-BINDING
PROTEIN


(Archaeoglobus
fulgidus)
PF10609
(ParA)
4 THR A 180
GLU A 178
THR A 182
VAL A 158
None
1.12A 1tv8A-2ph1A:
2.8
1tv8A-2ph1A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pkq GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
B


(Spinacia
oleracea)
PF00044
(Gp_dh_N)
PF02672
(CP12)
PF02800
(Gp_dh_C)
4 THR O 179
GLU O 314
SER O 238
VAL O 240
SO4  O 370 (-3.8A)
NDP  O 363 (-4.3A)
None
None
1.19A 1tv8A-2pkqO:
undetectable
1tv8A-2pkqO:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r66 GLYCOSYL
TRANSFERASE, GROUP 1


(Halothermothrix
orenii)
PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth)
4 TYR A 352
THR A 365
GLU A 369
SER A 269
None
1.05A 1tv8A-2r66A:
undetectable
1tv8A-2r66A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ux0 CALCIUM-CALMODULIN
DEPENDENT PROTEIN
KINASE (CAM KINASE)
II GAMMA


(Homo sapiens)
PF08332
(CaMKII_AD)
4 TYR A 516
THR A 461
THR A 484
SER A 498
None
1.03A 1tv8A-2ux0A:
undetectable
1tv8A-2ux0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vvg KINESIN-2

(Giardia
intestinalis)
PF00225
(Kinesin)
4 TYR A 287
THR A  92
THR A 306
VAL A 274
None
1.18A 1tv8A-2vvgA:
undetectable
1tv8A-2vvgA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbe BIPOLAR KINESIN
KRP-130


(Drosophila
melanogaster)
PF00225
(Kinesin)
4 TYR C 296
THR C  86
THR C 315
VAL C 283
None
1.06A 1tv8A-2wbeC:
undetectable
1tv8A-2wbeC:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y5w KINESIN HEAVY CHAIN

(Drosophila
melanogaster)
PF00225
(Kinesin)
4 TYR A 285
THR A  87
THR A 304
VAL A 271
None
1.02A 1tv8A-2y5wA:
undetectable
1tv8A-2y5wA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zws NEUTRAL CERAMIDASE

(Pseudomonas
aeruginosa)
PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C)
4 TYR A 460
THR A 380
THR A 389
SER A 447
GOL  A 656 (-4.5A)
None
None
None
1.20A 1tv8A-2zwsA:
undetectable
1tv8A-2zwsA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6u KINESIN-LIKE PROTEIN
KIF3B


(Homo sapiens)
PF00225
(Kinesin)
4 TYR A 292
THR A  91
THR A 311
VAL A 278
None
1.18A 1tv8A-3b6uA:
undetectable
1tv8A-3b6uA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6v KINESIN-LIKE PROTEIN
KIF3C


(Homo sapiens)
PF00225
(Kinesin)
4 TYR A 317
THR A  92
THR A 336
VAL A 303
None
1.09A 1tv8A-3b6vA:
undetectable
1tv8A-3b6vA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bbl REGULATORY PROTEIN
OF LACI FAMILY


(Chloroflexus
aggregans)
PF13377
(Peripla_BP_3)
4 THR A  73
GLU A 107
SER A 131
VAL A 198
None
1.16A 1tv8A-3bblA:
undetectable
1tv8A-3bblA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brz TODX

(Pseudomonas
putida)
PF03349
(Toluene_X)
4 THR A 226
THR A 150
SER A 142
VAL A  87
None
1.07A 1tv8A-3brzA:
undetectable
1tv8A-3brzA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctm CARBONYL REDUCTASE

(Candida
parapsilosis)
PF13561
(adh_short_C2)
4 TYR A  54
THR A 265
SER A 166
VAL A 116
None
1.12A 1tv8A-3ctmA:
2.4
1tv8A-3ctmA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d02 PUTATIVE LACI-TYPE
TRANSCRIPTIONAL
REGULATOR


(Klebsiella
pneumoniae)
PF13407
(Peripla_BP_4)
4 GLU A 195
SER A 219
VAL A 217
MET A 208
GOL  A   4 (-2.7A)
None
None
None
1.21A 1tv8A-3d02A:
undetectable
1tv8A-3d02A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddr HASR PROTEIN

(Serratia
marcescens)
PF00593
(TonB_dep_Rec)
PF07715
(Plug)
4 THR A 704
GLU A 689
SER A 124
VAL A 206
None
1.07A 1tv8A-3ddrA:
undetectable
1tv8A-3ddrA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnq GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE, TYPE
I


(Burkholderia
pseudomallei)
PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C)
4 THR A 184
GLU A 317
SER A 242
VAL A 244
None
1.10A 1tv8A-3gnqA:
undetectable
1tv8A-3gnqA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jap EIF3A
EIF3C


(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae)
PF00411
(Ribosomal_S11)
PF00203
(Ribosomal_S19)
4 THR o 490
THR o 481
SER p 734
VAL p 777
None
1.07A 1tv8A-3japo:
undetectable
1tv8A-3japo:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kin KINESIN HEAVY CHAIN
KINESIN HEAVY CHAIN


(Rattus
norvegicus;
Rattus
norvegicus)
PF00225
(Kinesin)
PF00225
(Kinesin)
4 TYR B 279
THR A  81
THR B 298
VAL B 265
None
1.13A 1tv8A-3kinB:
undetectable
1tv8A-3kinB:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qv2 5-CYTOSINE DNA
METHYLTRANSFERASE


(Entamoeba
histolytica)
PF00145
(DNA_methylase)
4 TYR A 169
GLU A  10
SER A  21
VAL A 308
None
1.01A 1tv8A-3qv2A:
undetectable
1tv8A-3qv2A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I


(Burkholderia
lata)
PF00117
(GATase)
PF00425
(Chorismate_bind)
5 THR A 314
GLU A 321
THR A 306
SER A 329
VAL A  72
None
1.21A 1tv8A-3r75A:
undetectable
1tv8A-3r75A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr1 PUTATIVE
D-GALACTONATE
DEHYDRATASE


(Ralstonia
pickettii)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 TYR A 326
THR A   7
GLU A  42
SER A 361
None
1.21A 1tv8A-3rr1A:
3.2
1tv8A-3rr1A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sql GLYCOSYL HYDROLASE
FAMILY 3


(Synechococcus
sp. PCC 7002)
PF00933
(Glyco_hydro_3)
4 THR A 131
THR A 130
SER A 359
MET A 506
None
1.23A 1tv8A-3sqlA:
2.6
1tv8A-3sqlA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1e HEMAGGLUTININ-NEURAM
INIDASE


(Avian
avulavirus 1)
PF00423
(HN)
4 THR A 470
THR A 526
SER A 543
VAL A 562
None
0.97A 1tv8A-3t1eA:
undetectable
1tv8A-3t1eA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6c PUTATIVE MAND FAMILY
DEHYDRATASE


(Pantoea
ananatis)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 THR A 322
SER A 344
VAL A 110
MET A  96
None
1.13A 1tv8A-3t6cA:
2.6
1tv8A-3t6cA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT


(Campylobacter
jejuni)
PF02091
(tRNA-synt_2e)
4 THR A  33
THR A  38
SER A  42
VAL A 150
ATP  A 288 (-3.7A)
None
None
None
1.10A 1tv8A-3ufgA:
undetectable
1tv8A-3ufgA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zfc CHROMOSOME-ASSOCIATE
D KINESIN KIF4


(Mus musculus)
PF00225
(Kinesin)
4 TYR A 289
THR A  83
THR A 308
VAL A 274
None
1.15A 1tv8A-3zfcA:
undetectable
1tv8A-3zfcA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bn2 KINESIN-LIKE PROTEIN
KIF15


(Homo sapiens)
PF00225
(Kinesin)
4 TYR A 301
THR A  90
THR A 320
VAL A 284
None
1.04A 1tv8A-4bn2A:
undetectable
1tv8A-4bn2A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1n IRON-SULFUR CLUSTER
BINDING PROTEIN


(Carboxydothermus
hydrogenoformans)
PF14574
(DUF4445)
4 TYR I 547
THR I 216
THR I 217
MET I 415
None
1.01A 1tv8A-4c1nI:
undetectable
1tv8A-4c1nI:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e1e FARNESYL
PYROPHOSPHATE
SYNTHASE


(Trypanosoma
cruzi)
PF00348
(polyprenyl_synt)
4 TYR A 324
THR A 208
THR A 209
VAL A 328
None
IPE  A 405 ( 4.6A)
None
None
1.19A 1tv8A-4e1eA:
undetectable
1tv8A-4e1eA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzh HEMAGGLUTININ-NEURAM
INIDASE


(Avian
avulavirus 1)
PF00423
(HN)
4 THR A 471
THR A 527
SER A 544
VAL A 563
None
1.07A 1tv8A-4fzhA:
undetectable
1tv8A-4fzhA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gul PIRIN

(Homo sapiens)
PF02678
(Pirin)
PF05726
(Pirin_C)
4 THR A 169
GLU A 244
THR A 167
VAL A 250
None
1.12A 1tv8A-4gulA:
undetectable
1tv8A-4gulA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ifa EXTRACELLULAR
PROTEIN CONTAINING A
SCP DOMAIN


(Bacillus
anthracis)
PF00188
(CAP)
PF14504
(CAP_assoc_N)
4 TYR A 174
THR A 192
SER A 301
VAL A 304
None
None
CL  A 401 (-3.7A)
None
1.14A 1tv8A-4ifaA:
undetectable
1tv8A-4ifaA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ihc MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN


(Dickeya
paradisiaca)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 THR A 322
SER A 344
VAL A 110
MET A  96
None
1.09A 1tv8A-4ihcA:
undetectable
1tv8A-4ihcA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jpw HEAVY CHAIN OF
ANTIBODY 12A21
LIGHT CHAIN OF
ANTIBODY 12A21


(Homo sapiens;
Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set)
4 TYR H 145
THR L 180
THR L 178
SER H 179
None
1.23A 1tv8A-4jpwH:
undetectable
1tv8A-4jpwH:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lb0 UNCHARACTERIZED
PROTEIN


(Agrobacterium
vitis)
PF05544
(Pro_racemase)
4 THR A 289
GLU A  15
THR A 309
SER A 141
None
1.06A 1tv8A-4lb0A:
undetectable
1tv8A-4lb0A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o29 PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE


(Pyrobaculum
aerophilum)
PF01135
(PCMT)
4 GLU A  78
SER A  83
VAL A  33
MET A  40
SAH  A 500 (-4.3A)
SAH  A 500 (-2.9A)
None
None
1.19A 1tv8A-4o29A:
undetectable
1tv8A-4o29A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pet EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 7


(Colwellia
psychrerythraea)
PF03480
(DctP)
4 TYR A 235
THR A 244
THR A 155
SER A 221
None
PYR  A 402 ( 4.1A)
PYR  A 402 ( 4.9A)
None
1.17A 1tv8A-4petA:
undetectable
1tv8A-4petA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rhz CRY23AA1

(Bacillus
thuringiensis)
PF03318
(ETX_MTX2)
4 TYR A 159
THR A 125
THR A 126
VAL A 114
None
1.17A 1tv8A-4rhzA:
undetectable
1tv8A-4rhzA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rn7 N-ACETYLMURAMOYL-L-A
LANINE AMIDASE


(Clostridioides
difficile)
PF01520
(Amidase_3)
4 THR A 266
GLU A 271
THR A 267
VAL A 237
None
1.15A 1tv8A-4rn7A:
undetectable
1tv8A-4rn7A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3j CORTICAL-LYTIC
ENZYME


(Bacillus cereus)
PF00704
(Glyco_hydro_18)
PF01476
(LysM)
4 TYR A 109
THR A 245
SER A 247
VAL A 279
None
0.85A 1tv8A-4s3jA:
3.3
1tv8A-4s3jA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uss GLUTATHIONYL
HYDROQUINONE
REDUCTASE


(Populus
trichocarpa)
PF13409
(GST_N_2)
PF13410
(GST_C_2)
4 GLU A 117
THR A  80
SER A 111
VAL A  73
None
1.21A 1tv8A-4ussA:
undetectable
1tv8A-4ussA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wpz CYTOCHROME P450

(Streptomyces
avermitilis)
PF00067
(p450)
4 THR A 286
THR A 288
VAL A  90
MET A  85
None
None
HEM  A 503 (-3.8A)
None
1.12A 1tv8A-4wpzA:
undetectable
1tv8A-4wpzA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y23 GAMMA GLUTAMYL
TRANSPEPTIDASE,GAMMA
-GLUTAMYLTRANSPEPTID
ASE


(Bacillus
licheniformis)
PF01019
(G_glu_transpept)
4 TYR A 237
GLU A 438
THR A 416
SER A 108
None
NA  A 601 (-4.4A)
None
None
1.19A 1tv8A-4y23A:
undetectable
1tv8A-4y23A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzk TRYPTOPHAN
DIMETHYLALLYLTRANSFE
RASE


(Streptomyces
blastmyceticus)
PF11991
(Trp_DMAT)
4 TYR A 348
GLU A 106
VAL A 334
MET A 343
None
1.18A 1tv8A-4yzkA:
undetectable
1tv8A-4yzkA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9x GLUCONATE
5-DEHYDROGENASE


(Streptococcus
pyogenes)
PF13561
(adh_short_C2)
4 TYR A 158
THR A 196
THR A 193
MET A 146
None
1.11A 1tv8A-4z9xA:
2.3
1tv8A-4z9xA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zm4 AMINOTRANSFERASE

(Streptomyces
pactum)
PF00202
(Aminotran_3)
4 THR A 338
GLU A 336
THR A 364
MET A 321
None
1.18A 1tv8A-4zm4A:
undetectable
1tv8A-4zm4A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5du9 CDA PEPTIDE
SYNTHETASE I


(Streptomyces
coelicolor)
PF00668
(Condensation)
4 TYR A 151
THR A  59
SER A 137
MET A 381
None
1.14A 1tv8A-5du9A:
undetectable
1tv8A-5du9A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5enz UDP-GLCNAC
2-EPIMERASE


(Staphylococcus
aureus)
PF02350
(Epimerase_2)
4 THR A 280
THR A 203
VAL A 265
MET A 178
None
UDP  A 401 ( 4.4A)
UDP  A 401 (-3.7A)
None
1.12A 1tv8A-5enzA:
3.2
1tv8A-5enzA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE


(Dinoroseobacter
shibae)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N)
5 THR A 243
GLU A 147
THR A 242
SER A 506
VAL A 525
None
GOL  A 705 (-2.8A)
None
None
None
1.29A 1tv8A-5gxdA:
undetectable
1tv8A-5gxdA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h8y SULFITE REDUCTASE
[FERREDOXIN],
CHLOROPLASTIC


(Zea mays)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
4 TYR A 389
GLU A 246
THR A 213
VAL A 339
None
1.22A 1tv8A-5h8yA:
undetectable
1tv8A-5h8yA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hkj COMPLEMENT C1Q
SUBCOMPONENT SUBUNIT
A,COMPLEMENT C1Q
SUBCOMPONENT SUBUNIT
C,COMPLEMENT C1Q
SUBCOMPONENT SUBUNIT
B


(Homo sapiens)
PF00386
(C1q)
4 THR A 328
THR A 366
SER A 229
VAL A 261
None
1.15A 1tv8A-5hkjA:
undetectable
1tv8A-5hkjA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hws 2-DEHYDROPANTOATE
2-REDUCTASE


(Thermococcus
kodakarensis)
PF02558
(ApbA)
PF08546
(ApbA_C)
4 THR A 240
GLU A 242
THR A 244
VAL A 196
None
1.11A 1tv8A-5hwsA:
undetectable
1tv8A-5hwsA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iwz SYNAPTONEMAL COMPLEX
PROTEIN 2


(Mus musculus)
no annotation 4 THR A 332
THR A 314
SER A 312
VAL A 210
None
1.12A 1tv8A-5iwzA:
undetectable
1tv8A-5iwzA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5klf CARBOHYDRATE BINDING
MODULE E1


(uncultured
bacterium)
no annotation 4 TYR A  52
GLU A  22
THR A  46
SER A  44
None
GD  A 111 ( 3.1A)
None
None
1.22A 1tv8A-5klfA:
undetectable
1tv8A-5klfA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kvu ISOCITRATE
DEHYDROGENASE


(Mycobacterium
tuberculosis)
PF03971
(IDH)
4 THR A 173
THR A 375
SER A 253
VAL A 349
None
1.18A 1tv8A-5kvuA:
undetectable
1tv8A-5kvuA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l6f FAD LINKED
OXIDASE-LIKE PROTEIN


(Thermothelomyces
thermophila)
PF01565
(FAD_binding_4)
PF08031
(BBE)
4 THR A 119
THR A 128
SER A 222
VAL A  70
None
1.19A 1tv8A-5l6fA:
undetectable
1tv8A-5l6fA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mm7 -

(-)
no annotation 4 TYR K 398
THR K 176
THR K 417
VAL K 385
None
1.16A 1tv8A-5mm7K:
undetectable
1tv8A-5mm7K:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5i TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT B
TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT FWDF


(Methanothermobacter
sp. CaT2;
Methanothermobacter
wolfeii)
PF00384
(Molybdopterin)
PF00037
(Fer4)
PF12838
(Fer4_7)
4 THR F 298
GLU B 173
THR F 299
VAL F 278
None
1.20A 1tv8A-5t5iF:
undetectable
1tv8A-5t5iF:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ur2 BIFUNCTIONAL PROTEIN
PUTA


(Bdellovibrio
bacteriovorus)
PF00171
(Aldedh)
PF01619
(Pro_dh)
4 TYR A 602
THR A 633
THR A 711
MET A 606
None
1.20A 1tv8A-5ur2A:
3.9
1tv8A-5ur2A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uyr BACTERIOPHYTOCHROME

(Xanthomonas
campestris)
no annotation 4 TYR A 221
THR A 289
GLU A 118
VAL A 248
None
None
None
BLA  A 900 (-4.0A)
0.95A 1tv8A-5uyrA:
undetectable
1tv8A-5uyrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v1s RADICAL SAM

(Streptococcus
suis)
PF04055
(Radical_SAM)
PF13394
(Fer4_14)
4 GLU A 161
THR A 185
SER A 210
VAL A 249
SAM  A 604 (-4.4A)
SAM  A 604 (-3.8A)
SAM  A 604 (-2.4A)
SAM  A 604 (-4.2A)
0.49A 1tv8A-5v1sA:
21.8
1tv8A-5v1sA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vbf NAD-DEPENDENT
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE


(Burkholderia
vietnamiensis)
PF00171
(Aldedh)
4 TYR A   9
GLU A 109
SER A 186
VAL A  31
None
None
UNX  A 604 ( 4.1A)
None
1.22A 1tv8A-5vbfA:
undetectable
1tv8A-5vbfA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vhs 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 3


(Homo sapiens)
PF01399
(PCI)
PF08375
(Rpn3_C)
4 TYR V 360
THR V 391
THR V 393
VAL V 334
None
1.18A 1tv8A-5vhsV:
undetectable
1tv8A-5vhsV:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wgg RADICAL SAM DOMAIN
PROTEIN


(Ruminiclostridium
thermocellum)
PF04055
(Radical_SAM)
PF13186
(SPASM)
PF13353
(Fer4_12)
4 TYR A 110
GLU A 155
THR A 186
SER A 210
SAM  A 504 (-4.8A)
SAM  A 504 (-3.7A)
SAM  A 504 (-4.2A)
SAM  A 504 (-2.5A)
0.40A 1tv8A-5wggA:
17.6
1tv8A-5wggA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wka BETA-GLUCOSIDASE

(metagenome)
no annotation 4 TYR A 453
GLU A 369
THR A  12
VAL A  69
None
GOL  A 501 (-3.4A)
None
None
1.21A 1tv8A-5wkaA:
6.0
1tv8A-5wkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x8z PENICILLIN V
ACYLASE-LIKE PROTEIN


(Shewanella
loihica)
no annotation 4 THR A  61
THR A  77
SER A  74
MET A  52
None
0.94A 1tv8A-5x8zA:
undetectable
1tv8A-5x8zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6r GENOME POLYPROTEIN

(Pestivirus C)
no annotation 4 GLU A 535
THR A 579
VAL A 566
MET A 143
None
1.00A 1tv8A-5y6rA:
undetectable
1tv8A-5y6rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yfb DIPEPTIDYL PEPTIDASE
3


(Armillaria
tabescens)
no annotation 4 TYR A 482
THR A 312
SER A 496
VAL A 491
None
1.11A 1tv8A-5yfbA:
undetectable
1tv8A-5yfbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yti FLAGELLAR HOOK
ASSOCIATED PROTEIN
TYPE 3 FLGL


(Legionella
pneumophila)
no annotation 4 TYR A 224
GLU A 216
THR A 214
MET A 226
None
1.22A 1tv8A-5ytiA:
undetectable
1tv8A-5ytiA:
undetectable