SIMILAR PATTERNS OF AMINO ACIDS FOR 1TUV_A_VK3A4558_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c8z | TUBBY PROTEIN (Mus musculus) |
PF01167(Tub) | 4 | TYR A 464LEU A 485MET A 391ILE A 422 | None | 1.15A | 1tuvA-1c8zA:undetectable | 1tuvA-1c8zA:16.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6y | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanosarcinabarkeri) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 4 | TYR A1253HIS A1127LEU A1123ILE A1245 | None | 1.13A | 1tuvA-1e6yA:3.2 | 1tuvA-1e6yA:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h8l | CARBOXYPEPTIDASEGP180 RESIDUES503-882 (Lophonettaspecularioides) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | GLU A 268LEU A 169MET A 116ILE A 70 | None | 1.11A | 1tuvA-1h8lA:undetectable | 1tuvA-1h8lA:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hg4 | ULTRASPIRACLE (Drosophilamelanogaster) |
PF00104(Hormone_recep) | 4 | TYR A 295GLU A 247TYR A 416ILE A 240 | None | 1.20A | 1tuvA-1hg4A:undetectable | 1tuvA-1hg4A:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hwn | EBULIN (Sambucus ebulus) |
PF00161(RIP) | 4 | TYR A 116GLU A 194LEU A 132ILE A 170 | None | 1.15A | 1tuvA-1hwnA:undetectable | 1tuvA-1hwnA:14.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kbl | PYRUVATE PHOSPHATEDIKINASE ([Clostridium]symbiosum) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 4 | HIS A 664LEU A 669MET A 578ILE A 579 | None | 1.08A | 1tuvA-1kblA:undetectable | 1tuvA-1kblA:9.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ks9 | 2-DEHYDROPANTOATE2-REDUCTASE (Escherichiacoli) |
PF02558(ApbA)PF08546(ApbA_C) | 4 | LEU A 156TYR A 151MET A 1ILE A 3 | None | 0.88A | 1tuvA-1ks9A:undetectable | 1tuvA-1ks9A:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lc0 | BILIVERDIN REDUCTASEA (Rattusnorvegicus) |
PF01408(GFO_IDH_MocA)PF09166(Biliv-reduc_cat) | 4 | TYR A 97GLU A 123MET A 129ILE A 249 | None | 0.98A | 1tuvA-1lc0A:undetectable | 1tuvA-1lc0A:15.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qox | BETA-GLUCOSIDASE (Bacilluscirculans) |
PF00232(Glyco_hydro_1) | 4 | TYR A 378HIS A 382LEU A 335TYR A 296 | None | 1.16A | 1tuvA-1qoxA:undetectable | 1tuvA-1qoxA:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uwi | BETA-GALACTOSIDASE (Sulfolobussolfataricus) |
PF00232(Glyco_hydro_1) | 4 | TYR A 401HIS A 405LEU A 368TYR A 322 | None | 1.20A | 1tuvA-1uwiA:undetectable | 1tuvA-1uwiA:12.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v02 | DHURRINASE (Sorghum bicolor) |
PF00232(Glyco_hydro_1) | 4 | TYR A 429HIS A 433LEU A 384TYR A 331 | None | 1.20A | 1tuvA-1v02A:undetectable | 1tuvA-1v02A:9.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vey | PEPTIDE DEFORMYLASE (Leptospirainterrogans) |
PF01327(Pep_deformylase) | 4 | HIS A 147LEU A 13TYR A 153ILE A 5 | ZN A1513 (-3.6A)NoneNoneNone | 1.18A | 1tuvA-1veyA:undetectable | 1tuvA-1veyA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vl0 | DTDP-4-DEHYDRORHAMNOSE REDUCTASE, RFBDORTHOLOG (Clostridiumacetobutylicum) |
PF04321(RmlD_sub_bind) | 4 | TYR A 144LEU A 193MET A 1ILE A 3 | None | 0.82A | 1tuvA-1vl0A:undetectable | 1tuvA-1vl0A:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vtk | THYMIDINE KINASE (Humanalphaherpesvirus1) |
PF00693(Herpes_TK) | 4 | TYR A 101GLU A 225LEU A 232TYR A 172 | TMP A 500 (-4.5A)TMP A 500 (-3.5A)NoneTMP A 500 (-3.7A) | 1.10A | 1tuvA-1vtkA:undetectable | 1tuvA-1vtkA:15.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w78 | FOLC BIFUNCTIONALPROTEIN (Escherichiacoli) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | TYR A 89HIS A 105TYR A 81ILE A 112 | None | 1.04A | 1tuvA-1w78A:undetectable | 1tuvA-1w78A:14.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1x7v | PA3566 PROTEIN (Pseudomonasaeruginosa) |
PF03992(ABM) | 4 | TYR A 41GLU A 57HIS A 68ILE A 90 | None | 0.41A | 1tuvA-1x7vA:14.8 | 1tuvA-1x7vA:31.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xup | GLYCEROL KINASE (Enterococcuscasseliflavus) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | TYR O 225HIS O 227LEU O 174ILE O 80 | None | 1.09A | 1tuvA-1xupO:undetectable | 1tuvA-1xupO:13.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bbe | HYPOTHETICAL PROTEINSO0527 (Shewanellaoneidensis) |
PF03992(ABM) | 4 | TYR A 50GLU A 66HIS A 77TYR A 86 | None | 0.78A | 1tuvA-2bbeA:14.0 | 1tuvA-2bbeA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fb0 | CONSERVEDHYPOTHETICAL PROTEIN (Bacteroidesthetaiotaomicron) |
PF03992(ABM) | 4 | TYR A 38GLU A 54HIS A 65MET A 84 | ACT A 901 (-4.7A)ACT A 901 (-2.9A)ACT A 901 (-3.9A)None | 0.62A | 1tuvA-2fb0A:13.2 | 1tuvA-2fb0A:25.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fja | ADENYLYLSULFATEREDUCTASE, SUBUNIT AADENYLYLSULFATEREDUCTASE, SUBUNIT B (Archaeoglobusfulgidus) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | GLU A 573HIS A 566LEU B 729ILE A 237 | NoneNoneSF4 B1100 ( 4.3A)None | 1.16A | 1tuvA-2fjaA:undetectable | 1tuvA-2fjaA:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gks | BIFUNCTIONAL SAT/APSKINASE (Aquifexaeolicus) |
PF01583(APS_kinase)PF01747(ATP-sulfurylase)PF14306(PUA_2) | 4 | TYR A 281HIS A 115LEU A 117ILE A 57 | None | 1.14A | 1tuvA-2gksA:undetectable | 1tuvA-2gksA:10.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gs4 | PROTEIN YCIF (Escherichiacoli) |
PF05974(DUF892) | 4 | GLU A 110HIS A 47LEU A 28MET A 78 | None | 1.06A | 1tuvA-2gs4A:undetectable | 1tuvA-2gs4A:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h63 | BILIVERDIN REDUCTASEA (Homo sapiens) |
PF01408(GFO_IDH_MocA)PF09166(Biliv-reduc_cat) | 4 | TYR A 98GLU A 124MET A 130ILE A 250 | NAP A 501 (-3.6A)NAP A 501 ( 3.9A)NoneNone | 1.02A | 1tuvA-2h63A:undetectable | 1tuvA-2h63A:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jf7 | STRICTOSIDINE-O-BETA-D-GLUCOSIDASE (Rauvolfiaserpentina) |
PF00232(Glyco_hydro_1) | 4 | TYR A 441HIS A 445LEU A 396TYR A 345 | None | 1.17A | 1tuvA-2jf7A:undetectable | 1tuvA-2jf7A:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2np0 | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 4 | TYR A 198GLU A 197LEU A 78ILE A 86 | None | 0.97A | 1tuvA-2np0A:undetectable | 1tuvA-2np0A:6.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbl | PUTATIVEESTERASE/LIPASE/THIOESTERASE (Ruegeria sp.TM1040) |
PF07859(Abhydrolase_3) | 4 | GLU A 214HIS A 135TYR A 72ILE A 13 | NoneUNL A 263 (-4.2A)UNL A 263 (-4.4A)None | 1.10A | 1tuvA-2pblA:undetectable | 1tuvA-2pblA:15.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qpm | CYTOKININDEHYDROGENASE 1 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | TYR A 431GLU A 288LEU A 458TYR A 491 | NoneNone246 A1536 (-4.3A)FAD A1535 ( 4.3A) | 1.05A | 1tuvA-2qpmA:3.8 | 1tuvA-2qpmA:13.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qux | COAT PROTEIN (Pseudomonasphage PP7) |
PF09063(Phage_coat) | 4 | HIS A 86LEU A 57TYR A 103ILE A 4 | None | 1.18A | 1tuvA-2quxA:undetectable | 1tuvA-2quxA:27.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r4j | AEROBICGLYCEROL-3-PHOSPHATEDEHYDROGENASE (Escherichiacoli) |
PF01266(DAO)PF16901(DAO_C) | 4 | TYR A 55HIS A 50LEU A 48ILE A 247 | 13P A1968 (-4.6A)FAD A 600 ( 4.6A)FAD A 600 (-4.1A)None | 0.97A | 1tuvA-2r4jA:2.2 | 1tuvA-2r4jA:12.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhy | 6-PHOSPHO-BETA-GLUCOSIDASE BGLA (Escherichiacoli) |
PF00232(Glyco_hydro_1) | 4 | TYR A 400HIS A 404LEU A 358TYR A 317 | None | 1.15A | 1tuvA-2xhyA:undetectable | 1tuvA-2xhyA:12.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xtq | COLICIN-M (Escherichiacoli) |
PF14859(Colicin_M) | 4 | TYR A 188HIS A 183LEU A 201ILE A 263 | None | 0.99A | 1tuvA-2xtqA:undetectable | 1tuvA-2xtqA:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xtq | COLICIN-M (Escherichiacoli) |
PF14859(Colicin_M) | 4 | TYR A 188HIS A 183LEU A 201ILE A 265 | None | 1.10A | 1tuvA-2xtqA:undetectable | 1tuvA-2xtqA:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afb | PUTATIVE CHITINASE (Pyrococcusfuriosus) |
no annotation | 4 | LEU A 476TYR A 516MET A 424ILE A 422 | None | 1.16A | 1tuvA-3afbA:undetectable | 1tuvA-3afbA:15.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3byh | FIMBRIN ABD2 (Homo sapiens) |
PF00307(CH) | 4 | LEU B 405TYR B 398MET B 608ILE B 611 | None | 1.08A | 1tuvA-3byhB:undetectable | 1tuvA-3byhB:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c5n | TUBBY-RELATEDPROTEIN 1 (Homo sapiens) |
PF01167(Tub) | 4 | TYR A 448LEU A 469MET A 375ILE A 406 | None | 1.18A | 1tuvA-3c5nA:undetectable | 1tuvA-3c5nA:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cgl | GFP-LIKE FLUORESCENTCHROMOPROTEINDSFP483 (Discosomastriata) |
PF01353(GFP) | 4 | TYR A 91LEU A 113TYR A 120ILE A 8 | NoneNoneCRQ A 66 ( 4.5A)None | 1.16A | 1tuvA-3cglA:undetectable | 1tuvA-3cglA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | TYR A 883HIS A 780LEU A 776ILE A 899 | None | 1.20A | 1tuvA-3dy5A:undetectable | 1tuvA-3dy5A:7.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0x | LIPASE-ESTERASERELATED PROTEIN (Clostridiumacetobutylicum) |
PF12146(Hydrolase_4) | 4 | TYR A 88HIS A 224LEU A 198MET A 165 | OXE A 243 (-4.2A)OXE A 243 (-4.1A)NoneOXE A 243 ( 4.6A) | 1.10A | 1tuvA-3e0xA:undetectable | 1tuvA-3e0xA:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e8o | UNCHARACTERIZEDPROTEIN WITHFERREDOXIN-LIKE FOLD (Deinococcusradiodurans) |
PF03992(ABM) | 4 | TYR A 55GLU A 71HIS A 82LEU A 83 | UNL A 200 (-4.4A)UNL A 200 (-2.8A)UNL A 200 (-4.1A)None | 0.68A | 1tuvA-3e8oA:13.1 | 1tuvA-3e8oA:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebr | UNCHARACTERIZEDRMLC-LIKE CUPIN (Cupriaviduspinatubonensis) |
PF12973(Cupin_7) | 4 | TYR A 74GLU A 89HIS A 57LEU A 117 | NonePEG A 161 ( 4.8A)NonePEG A 160 ( 4.7A) | 1.11A | 1tuvA-3ebrA:undetectable | 1tuvA-3ebrA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f08 | UNCHARACTERIZEDPROTEIN Q6HG14 (Bacillusthuringiensis) |
PF10604(Polyketide_cyc2) | 4 | TYR A 72GLU A 58LEU A 31TYR A 125 | None | 1.05A | 1tuvA-3f08A:undetectable | 1tuvA-3f08A:27.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fjo | NADPH-CYTOCHROMEP450 REDUCTASE (Homo sapiens;Saccharomycescerevisiae) |
PF00175(NAD_binding_1)PF00258(Flavodoxin_1)PF00667(FAD_binding_1) | 4 | GLU A 558LEU A 272TYR A 553ILE A 521 | None | 1.03A | 1tuvA-3fjoA:undetectable | 1tuvA-3fjoA:10.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fkf | THIOL-DISULFIDEOXIDOREDUCTASE (Bacteroidesfragilis) |
PF13905(Thioredoxin_8) | 4 | GLU A 51LEU A 34TYR A 59ILE A 129 | None | 1.05A | 1tuvA-3fkfA:undetectable | 1tuvA-3fkfA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4g | SUSD-LIKECARBOHYDRATE BINDINGPROTEIN BF1063 (Bacteroidesfragilis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | GLU A 465LEU A 257TYR A 339ILE A 250 | None | 0.96A | 1tuvA-3i4gA:undetectable | 1tuvA-3i4gA:11.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jtw | DIHYDROFOLATEREDUCTASE (Pediococcuspentosaceus) |
PF01872(RibD_C) | 4 | TYR A 44LEU A 64TYR A 69MET A 52 | None | 1.19A | 1tuvA-3jtwA:undetectable | 1tuvA-3jtwA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lag | UNCHARACTERIZEDPROTEIN RPA4178 (Rhodopseudomonaspalustris) |
PF07883(Cupin_2) | 4 | TYR A 38GLU A 90HIS A 34MET A 48 | FMT A 100 (-4.4A)FMT A 100 (-2.9A) NI A 98 ( 3.2A)None | 1.16A | 1tuvA-3lagA:undetectable | 1tuvA-3lagA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ls2 | S-FORMYLGLUTATHIONEHYDROLASE (Pseudoalteromonashaloplanktis) |
PF00756(Esterase) | 4 | TYR A 122HIS A 20LEU A 2ILE A 131 | None | 1.14A | 1tuvA-3ls2A:undetectable | 1tuvA-3ls2A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lso | PUTATIVE MEMBRANEANCHORED PROTEIN (Corynebacteriumdiphtheriae) |
PF16640(Big_3_5) | 4 | GLU B 299HIS B 253LEU B 478ILE B 301 | None | 0.97A | 1tuvA-3lsoB:undetectable | 1tuvA-3lsoB:10.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mwe | ATP-CITRATE SYNTHASE (Homo sapiens) |
PF16114(Citrate_bind) | 4 | TYR A 307LEU A 338MET A 391ILE A 361 | None | 1.21A | 1tuvA-3mweA:undetectable | 1tuvA-3mweA:14.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nmb | PUTATIVE SUGARHYDROLASE (Bacteroidesovatus) |
PF06439(DUF1080) | 4 | TYR A 137HIS A 218LEU A 226MET A 238 | None | 1.19A | 1tuvA-3nmbA:undetectable | 1tuvA-3nmbA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nn2 | CHLORITE DISMUTASE (Nitrospiradefluvii) |
PF06778(Chlor_dismutase) | 4 | HIS A 177LEU A 175TYR A 110ILE A 139 | NoneCYN A 245 ( 4.0A)PO4 A 240 ( 4.4A)HEM A 239 (-3.8A) | 1.11A | 1tuvA-3nn2A:5.1 | 1tuvA-3nn2A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nn2 | CHLORITE DISMUTASE (Nitrospiradefluvii) |
PF06778(Chlor_dismutase) | 4 | TYR A 176HIS A 72LEU A 52MET A 226 | None | 1.20A | 1tuvA-3nn2A:5.1 | 1tuvA-3nn2A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pyz | BIFUNCTIONALFOLYLPOLYGLUTAMATESYNTHASE/DIHYDROFOLATE SYNTHASE (Yersinia pestis) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | TYR A 89HIS A 105LEU A 134TYR A 81 | None | 1.17A | 1tuvA-3pyzA:undetectable | 1tuvA-3pyzA:13.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qfs | NADPH--CYTOCHROMEP450 REDUCTASE (Homo sapiens) |
PF00175(NAD_binding_1)PF00667(FAD_binding_1) | 4 | GLU A 581LEU A 295TYR A 576ILE A 544 | None | 1.06A | 1tuvA-3qfsA:undetectable | 1tuvA-3qfsA:13.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qom | 6-PHOSPHO-BETA-GLUCOSIDASE (Lactobacillusplantarum) |
PF00232(Glyco_hydro_1) | 4 | TYR A 398HIS A 402LEU A 356TYR A 317 | NoneNoneNoneBGC A 479 ( 4.8A) | 1.18A | 1tuvA-3qomA:undetectable | 1tuvA-3qomA:13.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qpi | CHLORITE DISMUTASE (Nitrobacterwinogradskyi) |
PF06778(Chlor_dismutase) | 4 | HIS A 131LEU A 129TYR A 61ILE A 90 | NoneHEM A1001 ( 4.6A)HEM A1001 (-4.5A)HEM A1001 ( 4.0A) | 1.02A | 1tuvA-3qpiA:4.6 | 1tuvA-3qpiA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u24 | PUTATIVE LIPOPROTEIN (Shewanellaoneidensis) |
PF05960(DUF885) | 4 | TYR A 463LEU A 575MET A 589ILE A 585 | None | 1.19A | 1tuvA-3u24A:undetectable | 1tuvA-3u24A:10.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ww3 | L-RIBOSE ISOMERASE (Cellulomonasparahominis) |
no annotation | 4 | GLU A 204HIS A 108MET A 63ILE A 65 | None MN A 401 (-3.3A)NoneNone | 0.90A | 1tuvA-3ww3A:undetectable | 1tuvA-3ww3A:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ww3 | L-RIBOSE ISOMERASE (Cellulomonasparahominis) |
no annotation | 4 | TYR A 115GLU A 204MET A 63ILE A 65 | None | 1.17A | 1tuvA-3ww3A:undetectable | 1tuvA-3ww3A:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d4z | DEOXYHYPUSINEHYDROXYLASE (Homo sapiens) |
PF13646(HEAT_2) | 4 | GLU A 93HIS A 89LEU A 204MET A 179 | GOL A 305 (-2.7A) FE A 301 (-3.4A)NoneNone | 1.15A | 1tuvA-4d4zA:undetectable | 1tuvA-4d4zA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4df9 | PUTATIVE PEPTIDASE (Bacteroidesfragilis) |
PF09471(Peptidase_M64)PF16217(M64_N) | 4 | TYR A 423HIS A 276TYR A 292ILE A 416 | None | 1.19A | 1tuvA-4df9A:undetectable | 1tuvA-4df9A:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dkj | CYTOSINE-SPECIFICMETHYLTRANSFERASE (Mycoplasmapenetrans) |
PF00145(DNA_methylase) | 4 | TYR A 131LEU A 234TYR A 210ILE A 128 | None | 1.08A | 1tuvA-4dkjA:undetectable | 1tuvA-4dkjA:12.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dpo | CONSERVED PROTEIN (Methanosarcinamazei) |
PF03992(ABM) | 4 | TYR A 40GLU A 56HIS A 67ILE A 90 | None | 0.33A | 1tuvA-4dpoA:14.1 | 1tuvA-4dpoA:23.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gpn | 6-PHOSPHO-BETA-D-GLUCOSIDASE (Streptococcusmutans) |
PF00232(Glyco_hydro_1) | 4 | TYR A 398HIS A 402LEU A 356TYR A 313 | NoneNoneNone6GB A 501 (-4.2A) | 1.12A | 1tuvA-4gpnA:undetectable | 1tuvA-4gpnA:11.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ipn | 6-PHOSPHO-BETA-GLUCOSIDASE (Streptococcuspneumoniae) |
PF00232(Glyco_hydro_1) | 4 | TYR B 391HIS B 395LEU B 345TYR B 303 | NoneNoneNone1FT B 501 ( 4.6A) | 1.05A | 1tuvA-4ipnB:undetectable | 1tuvA-4ipnB:11.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k2b | NTD BIOSYNTHESISOPERON PROTEIN NTDA (Bacillussubtilis) |
PF01041(DegT_DnrJ_EryC1) | 4 | HIS A 407LEU A 382TYR A 379ILE A 170 | None | 1.13A | 1tuvA-4k2bA:undetectable | 1tuvA-4k2bA:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mla | CYTOKININ OXIDASE 2 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | TYR A 406GLU A 269LEU A 433TYR A 469 | NoneNoneNoneFAD A 601 (-4.4A) | 1.07A | 1tuvA-4mlaA:4.2 | 1tuvA-4mlaA:11.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mni | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Polaromonas sp.JS666) |
PF03480(DctP) | 4 | TYR A 270GLU A 274TYR A 44ILE A 211 | NoneNone173 A 401 (-4.8A)None | 1.15A | 1tuvA-4mniA:undetectable | 1tuvA-4mniA:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n5c | CARGO-TRANSPORTPROTEIN YPP1 (Saccharomycescerevisiae) |
no annotation | 4 | TYR A 145GLU A 149HIS A 52LEU A 51 | None | 1.04A | 1tuvA-4n5cA:undetectable | 1tuvA-4n5cA:8.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oal | CYTOKININDEHYDROGENASE 4 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | TYR A 425GLU A 285LEU A 452TYR A 487 | NoneNone245 A 602 (-4.1A)FAD A 601 ( 4.6A) | 1.03A | 1tuvA-4oalA:2.9 | 1tuvA-4oalA:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ols | ENDOLYSIN (Staphylococcusvirus G15) |
PF01510(Amidase_2) | 4 | GLU A 298HIS A 340LEU A 359ILE A 213 | None | 1.17A | 1tuvA-4olsA:undetectable | 1tuvA-4olsA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ptx | GLYCOSIDE HYDROLASEFAMILY 1 (Halothermothrixorenii) |
PF00232(Glyco_hydro_1) | 4 | TYR A 377HIS A 381LEU A 334TYR A 296 | NoneNoneNoneBGC A 501 (-4.1A) | 1.14A | 1tuvA-4ptxA:undetectable | 1tuvA-4ptxA:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q0s | L-RIBOSE ISOMERASE (Acinetobactersp. DL-28) |
no annotation | 4 | GLU A 204HIS A 108MET A 63ILE A 65 | RB0 A 502 (-3.1A) CO A 501 ( 3.3A)RB0 A 502 ( 4.4A)None | 0.93A | 1tuvA-4q0sA:undetectable | 1tuvA-4q0sA:16.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4upl | SULFATASE FAMILYPROTEIN (Ruegeriapomeroyi) |
PF00884(Sulfatase)PF16347(DUF4976) | 4 | GLU A 338HIS A 232TYR A 145ILE A 48 | None | 1.18A | 1tuvA-4uplA:undetectable | 1tuvA-4uplA:9.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wat | PFRH5 (Plasmodiumfalciparum) |
no annotation | 4 | TYR A 242HIS A 496MET A 401ILE A 407 | None | 1.14A | 1tuvA-4watA:undetectable | 1tuvA-4watA:11.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wat | PFRH5 (Plasmodiumfalciparum) |
no annotation | 4 | TYR A 242HIS A 496TYR A 252ILE A 410 | None | 0.84A | 1tuvA-4watA:undetectable | 1tuvA-4watA:11.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y07 | NEDD4-LIKE E3UBIQUITIN-PROTEINLIGASE WWP2 (Homo sapiens) |
PF00632(HECT) | 4 | HIS A 618LEU A 544MET A 535ILE A 532 | None | 1.08A | 1tuvA-4y07A:undetectable | 1tuvA-4y07A:13.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ymk | ACYL-COA DESATURASE1 (Mus musculus) |
PF00487(FA_desaturase) | 4 | TYR A 272GLU A 280TYR A 309ILE A 282 | None | 1.13A | 1tuvA-4ymkA:undetectable | 1tuvA-4ymkA:14.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfm | PUTATIVE6-PHOSPHO-BETA-GALACTOBIOSIDASE (Geobacillusstearothermophilus) |
PF00232(Glyco_hydro_1) | 4 | TYR A 401HIS A 405LEU A 359TYR A 301 | None | 1.18A | 1tuvA-4zfmA:undetectable | 1tuvA-4zfmA:11.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zsl | MITOGEN-ACTIVATEDPROTEIN KINASE 7 (Homo sapiens) |
PF00069(Pkinase) | 4 | LEU A 234TYR A 297MET A 275ILE A 274 | None | 1.07A | 1tuvA-4zslA:undetectable | 1tuvA-4zslA:13.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a31 | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1THEANAPHASE-PROMOTINGCOMPLEX CHAIN R (Homo sapiens) |
PF00400(WD40)PF12859(ANAPC1)PF12894(ANAPC4_WD40) | 4 | TYR R 91HIS A1231LEU A1209ILE A1193 | None | 0.98A | 1tuvA-5a31R:undetectable | 1tuvA-5a31R:12.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5avp | L-RIBOSE ISOMERASE (Geodermatophilusobscurus) |
no annotation | 4 | GLU A 208HIS A 112MET A 67ILE A 69 | None MN A 401 (-3.5A)NoneNone | 0.92A | 1tuvA-5avpA:undetectable | 1tuvA-5avpA:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b7z | UNCHARACTERIZEDPROTEIN TM_0416 (Thermotogamaritima) |
PF01261(AP_endonuc_2) | 4 | GLU A 243HIS A 185LEU A 151ILE A 110 | NI A 305 (-2.5A)NoneNoneNone | 1.15A | 1tuvA-5b7zA:undetectable | 1tuvA-5b7zA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e1r | 7S VICILIN (Caryaillinoinensis) |
PF00190(Cupin_1) | 4 | TYR A 432GLU A 476LEU A 493ILE A 440 | None | 1.04A | 1tuvA-5e1rA:undetectable | 1tuvA-5e1rA:12.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e4y | HOMOSERINEO-ACETYLTRANSFERASE (Pseudomonasveronii) |
PF00561(Abhydrolase_1) | 4 | GLU A 24HIS A 269TYR A 152ILE A 112 | None | 1.21A | 1tuvA-5e4yA:undetectable | 1tuvA-5e4yA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ehk | LANTIBIOTICDEHYDRATASE (Microbisporacorallina) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 4 | GLU A 280HIS A 183LEU A 179ILE A 574 | None | 0.88A | 1tuvA-5ehkA:6.6 | 1tuvA-5ehkA:6.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5n | MONOOXYGENASE (Micromonosporasp. TP-A0468) |
PF05368(NmrA) | 4 | HIS A 275LEU A 278MET A 152ILE A 182 | GOL A 307 ( 4.6A)NoneNoneNone | 1.00A | 1tuvA-5f5nA:undetectable | 1tuvA-5f5nA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fa9 | PEPTIDE METHIONINESULFOXIDE REDUCTASEMSRA (Treponemadenticola) |
PF01625(PMSR)PF01641(SelR) | 4 | LEU A 7TYR A 58MET A 103ILE A 107 | None | 0.89A | 1tuvA-5fa9A:2.9 | 1tuvA-5fa9A:16.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jld | ARGINYL-TRNASYNTHETASE, PUTATIVE (Plasmodiumfalciparum) |
PF00750(tRNA-synt_1d)PF03485(Arg_tRNA_synt_N)PF05746(DALR_1) | 4 | TYR A 538LEU A 577MET A 4ILE A 116 | None | 0.86A | 1tuvA-5jldA:undetectable | 1tuvA-5jldA:10.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ket | ALDO-KETO REDUCTASE1 (Coptotermesgestroi) |
PF00248(Aldo_ket_red) | 4 | TYR A 52HIS A 114LEU A 115TYR A 214 | NAP A 400 (-4.8A)NAP A 400 (-4.3A)NoneNAP A 400 (-3.6A) | 1.04A | 1tuvA-5ketA:undetectable | 1tuvA-5ketA:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m32 | PROTEASOME SUBUNITBETA TYPE-2 (Homo sapiens) |
PF00227(Proteasome) | 4 | TYR J 147LEU J 115TYR J 12ILE J 5 | None | 1.12A | 1tuvA-5m32J:undetectable | 1tuvA-5m32J:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mau | CHLORITE DISMUTASE (Cyanothece sp.PCC 7425) |
no annotation | 4 | HIS A 131LEU A 129TYR A 61ILE A 90 | NoneHEM A 201 ( 4.2A)HEM A 201 (-4.7A)HEM A 201 ( 3.5A) | 1.06A | 1tuvA-5mauA:5.0 | 1tuvA-5mauA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tj7 | NEDD4-LIKE E3UBIQUITIN-PROTEINLIGASE WWP2 (Homo sapiens) |
PF00397(WW)PF00632(HECT) | 4 | HIS A 618LEU A 544MET A 535ILE A 532 | None | 1.02A | 1tuvA-5tj7A:undetectable | 1tuvA-5tj7A:13.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uj1 | DNA TOPOISOMERASE 1 (Mycobacteriumtuberculosis) |
no annotation | 4 | TYR A 517LEU A 526TYR A 580ILE A 544 | None | 1.18A | 1tuvA-5uj1A:undetectable | 1tuvA-5uj1A:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wka | BETA-GLUCOSIDASE (metagenome) |
no annotation | 4 | TYR A 392HIS A 396LEU A 349TYR A 292 | NoneNoneNoneGOL A 501 (-4.3A) | 1.19A | 1tuvA-5wkaA:undetectable | 1tuvA-5wkaA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgz | BETA-GLYCOSIDASE (unculturedmicroorganism) |
no annotation | 4 | TYR A 379HIS A 383LEU A 336TYR A 299 | NoneNoneNoneGOL A 501 (-4.3A) | 1.18A | 1tuvA-5xgzA:undetectable | 1tuvA-5xgzA:23.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cdw | EFFECTOR PROTEINLEM4 (LPG1101) (Legionellapneumophila) |
no annotation | 4 | TYR A 102LEU A 107TYR A 63ILE A 30 | None | 1.20A | 1tuvA-6cdwA:undetectable | 1tuvA-6cdwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cxh | PARTICULATE METHANEMONOOXYGENASE, CSUBUNIT (Methylomicrobiumalcaliphilum) |
no annotation | 4 | TYR C 174HIS C 106LEU C 110ILE C 234 | None | 1.16A | 1tuvA-6cxhC:undetectable | 1tuvA-6cxhC:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dd6 | PHOTOLYASE PHRB (Agrobacteriumtumefaciens) |
no annotation | 4 | TYR A 391LEU A 337MET A 351ILE A 355 | FAD A 601 (-3.7A)NoneNoneNone | 1.09A | 1tuvA-6dd6A:undetectable | 1tuvA-6dd6A:undetectable |