SIMILAR PATTERNS OF AMINO ACIDS FOR 1T9W_A_NFNA6001_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lsh LIPOVITELLIN (LV-1N,
LV-1C)

(Ichthyomyzon
unicuspis) 		PF01347
(Vitellogenin_N)
PF09172
(DUF1943) 		3 SER A 939
GLY A 938
ARG A 331
 None
 0.62A 1t9wA-1lshA:
2.2		 1t9wA-1lshA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mwo ALPHA AMYLASE

(Pyrococcus
woesei) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		3 SER A 136
GLY A 137
ARG A 112
 None
 0.45A 1t9wA-1mwoA:
0.0		 1t9wA-1mwoA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1spx SHORT-CHAIN
REDUCTASE FAMILY
MEMBER (5L265)

(Caenorhabditis
elegans) 		PF13561
(adh_short_C2) 		3 SER A 151
GLY A 152
ARG A 174
 None
 0.60A 1t9wA-1spxA:
0.0		 1t9wA-1spxA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u5u ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		no annotation 3 SER A 227
GLY A 228
ARG A 249
 None
 0.45A 1t9wA-1u5uA:
0.0		 1t9wA-1u5uA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6z EXOPOLYPHOSPHATASE

(Escherichia
coli) 		PF02541
(Ppx-GppA) 		3 SER A  20
GLY A  19
ARG A  93
 SO4  A 701 (-3.0A)
SO4  A 701 (-3.4A)
None
 0.66A 1t9wA-1u6zA:
3.0		 1t9wA-1u6zA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w27 PHENYLALANINE
AMMONIA-LYASE 1

(Petroselinum
crispum) 		PF00221
(Lyase_aromatic) 		3 SER A  78
GLY A  79
ARG A 157
 None
 0.65A 1t9wA-1w27A:
1.5		 1t9wA-1w27A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y3t HYPOTHETICAL PROTEIN
YXAG

(Bacillus
subtilis) 		PF07883
(Cupin_2) 		3 SER A  20
GLY A 264
ARG A 111
 None
 0.62A 1t9wA-1y3tA:
0.0		 1t9wA-1y3tA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yfm FUMARASE

(Saccharomyces
cerevisiae) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		3 SER A 325
GLY A 324
ARG A 211
 None
 0.66A 1t9wA-1yfmA:
0.0		 1t9wA-1yfmA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z47 PUTATIVE
ABC-TRANSPORTER
ATP-BINDING PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		3 SER A 311
GLY A 310
ARG A 181
 None
 0.57A 1t9wA-1z47A:
0.0		 1t9wA-1z47A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zrt CYTOCHROME B

(Rhodobacter
capsulatus) 		PF00032
(Cytochrom_B_C)
PF00033
(Cytochrome_B) 		3 SER C 155
GLY C 152
ARG C  94
 None
None
HEM  C 501 (-2.7A)
 0.67A 1t9wA-1zrtC:
undetectable		 1t9wA-1zrtC:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2acv TRITERPENE
UDP-GLUCOSYL
TRANSFERASE UGT71G1

(Medicago
truncatula) 		PF00201
(UDPGT) 		3 SER A 407
GLY A 406
ARG A 169
 None
 0.67A 1t9wA-2acvA:
undetectable		 1t9wA-2acvA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		3 SER A1007
GLY A1008
ARG A1435
 None
 0.65A 1t9wA-2b39A:
3.7		 1t9wA-2b39A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fmm PROTEIN EMSY

(Homo sapiens) 		PF03735
(ENT) 		3 SER E  84
GLY E  85
ARG E  36
 None
 0.60A 1t9wA-2fmmE:
2.8		 1t9wA-2fmmE:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6y GREEN FLUORESCENT
PROTEIN 2

(Pontellina
plumata) 		PF01353
(GFP) 		3 SER A 172
GLY A 152
ARG A 195
 None
None
CR2  A  58 ( 4.9A)
 0.63A 1t9wA-2g6yA:
undetectable		 1t9wA-2g6yA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggq 401AA LONG
HYPOTHETICAL
GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E

(Sulfurisphaera
tokodaii) 		PF00132
(Hexapep)
PF00483
(NTP_transferase) 		3 SER A  10
GLY A   9
ARG A 179
 TTP  A 500 (-2.6A)
TTP  A 500 (-3.0A)
TTP  A 500 (-3.3A)
 0.39A 1t9wA-2ggqA:
undetectable		 1t9wA-2ggqA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hlp MALATE DEHYDROGENASE

(Haloarcula
marismortui) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 SER A  91
GLY A  90
ARG A  79
 None
 0.55A 1t9wA-2hlpA:
undetectable		 1t9wA-2hlpA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbr URIDINE
DIPHOSPHO-N-ACETYLEN
OLPYRUVYLGLUCOSAMINE
REDUCTASE

(Escherichia
coli) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		3 SER A 229
GLY A 228
ARG A 214
 EPU  A 402 (-3.0A)
EPU  A 402 ( 3.5A)
FAD  A 401 ( 2.8A)
 0.65A 1t9wA-2mbrA:
2.1		 1t9wA-2mbrA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nad NAD-DEPENDENT
FORMATE
DEHYDROGENASE

(Pseudomonas sp.
101) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 SER A 334
GLY A 335
ARG A 284
 NAD  A 394 (-2.9A)
NAD  A 394 (-3.4A)
AZI  A 395 ( 3.0A)
 0.41A 1t9wA-2nadA:
undetectable		 1t9wA-2nadA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ozo TYROSINE-PROTEIN
KINASE ZAP-70

(Homo sapiens) 		PF00017
(SH2)
PF07714
(Pkinase_Tyr) 		3 SER A  14
GLY A  13
ARG A 119
 None
 0.37A 1t9wA-2ozoA:
undetectable		 1t9wA-2ozoA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r8a LONG-CHAIN FATTY
ACID TRANSPORT
PROTEIN

(Escherichia
coli) 		PF03349
(Toluene_X) 		3 SER A 370
GLY A 344
ARG A 326
 None
 0.55A 1t9wA-2r8aA:
undetectable		 1t9wA-2r8aA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7l AGGLUTININ-LIKE ALS9
PROTEIN

(Candida
albicans) 		PF11766
(Candida_ALS_N) 		3 SER A 124
GLY A 123
ARG A 171
 None
 0.60A 1t9wA-2y7lA:
undetectable		 1t9wA-2y7lA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z5l TYLACTONE SYNTHASE
STARTER MODULE AND
MODULES 1 & 2

(Streptomyces
fradiae) 		PF08659
(KR) 		3 SER A 234
GLY A 445
ARG A 257
 None
 0.66A 1t9wA-2z5lA:
1.7		 1t9wA-2z5lA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zai OLIGOSACCHARYL
TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN

(Pyrococcus
furiosus) 		no annotation 3 SER A 876
GLY A 877
ARG A 588
 None
 0.64A 1t9wA-2zaiA:
undetectable		 1t9wA-2zaiA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9g PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrobaculum
aerophilum) 		PF07995
(GSDH) 		3 SER A 304
GLY A 303
ARG A 352
 None
 0.68A 1t9wA-3a9gA:
undetectable		 1t9wA-3a9gA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aoe GLUTAMATE
DEHYDROGENASE

(Thermus
thermophilus) 		no annotation 3 SER E 344
GLY E 345
ARG E 397
 None
 0.67A 1t9wA-3aoeE:
2.9		 1t9wA-3aoeE:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3be4 ADENYLATE KINASE

(Cryptosporidium
parvum) 		PF00406
(ADK)
PF05191
(ADK_lid) 		3 SER A  16
GLY A  15
ARG A  93
 AP5  A 219 (-3.7A)
AP5  A 219 (-3.3A)
AP5  A 219 (-2.6A)
 0.62A 1t9wA-3be4A:
undetectable		 1t9wA-3be4A:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eei 5-METHYLTHIOADENOSIN
E
NUCLEOSIDASE/S-ADENO
SYLHOMOCYSTEINE
NUCLEOSIDASE

(Neisseria
meningitidis) 		PF01048
(PNP_UDP_1) 		3 SER A  51
GLY A  52
ARG A 197
 None
None
MTM  A 234 (-3.6A)
 0.64A 1t9wA-3eeiA:
undetectable		 1t9wA-3eeiA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fn4 NAD-DEPENDENT
FORMATE
DEHYDROGENASE

(Moraxella sp.) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 SER A 334
GLY A 335
ARG A 284
 GOL  A 402 (-3.4A)
GOL  A 402 (-3.5A)
GOL  A 402 (-2.5A)
 0.37A 1t9wA-3fn4A:
undetectable		 1t9wA-3fn4A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gtd FUMARATE HYDRATASE
CLASS II

(Rickettsia
prowazekii) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		3 SER A 300
GLY A 299
ARG A 186
 None
 0.69A 1t9wA-3gtdA:
undetectable		 1t9wA-3gtdA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7l ENDOGLUCANASE

(Vibrio
parahaemolyticus) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		3 SER A 435
GLY A 436
ARG A 544
 None
 0.66A 1t9wA-3h7lA:
undetectable		 1t9wA-3h7lA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrp UNCHARACTERIZED
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01833
(TIG) 		3 SER A 133
GLY A 134
ARG A 176
 None
 0.58A 1t9wA-3hrpA:
undetectable		 1t9wA-3hrpA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hx3 RETINALDEHYDE-BINDIN
G PROTEIN 1

(Homo sapiens) 		PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N) 		3 SER A  76
GLY A  77
ARG A 115
 None
 0.60A 1t9wA-3hx3A:
undetectable		 1t9wA-3hx3A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i99 UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(Vibrio cholerae) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		3 SER A 242
GLY A 241
ARG A 227
 PO4  A 359 (-2.9A)
FAD  A 358 (-3.6A)
FAD  A 358 (-3.1A)
 0.68A 1t9wA-3i99A:
3.0		 1t9wA-3i99A:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN

(Montipora sp.
20) 		PF01353
(GFP) 		3 SER A 175
GLY A 155
ARG A 193
 None
None
CRQ  A  64 ( 4.2A)
 0.67A 1t9wA-3ir8A:
undetectable		 1t9wA-3ir8A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3itd 17BETA-HYDROXYSTEROI
D DEHYDROGENASE

(Curvularia
lunata) 		PF13561
(adh_short_C2) 		3 SER A  68
GLY A  67
ARG A  15
 None
 0.52A 1t9wA-3itdA:
undetectable		 1t9wA-3itdA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2z LYSOSOMAL PRO-X
CARBOXYPEPTIDASE

(Homo sapiens) 		PF05577
(Peptidase_S28) 		3 SER B 179
GLY B 178
ARG B 460
 None
 0.69A 1t9wA-3n2zB:
undetectable		 1t9wA-3n2zB:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nix FLAVOPROTEIN/DEHYDRO
GENASE

(Cytophaga
hutchinsonii) 		PF01494
(FAD_binding_3) 		3 SER A 178
GLY A 179
ARG A 183
 None
 0.68A 1t9wA-3nixA:
undetectable		 1t9wA-3nixA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgv ALPHA AMYLASE

(Pyrococcus
woesei) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		3 SER A 136
GLY A 137
ARG A 112
 None
 0.52A 1t9wA-3qgvA:
undetectable		 1t9wA-3qgvA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qnb OXACILLINASE

(Escherichia
coli) 		PF00905
(Transpeptidase) 		3 SER A 147
GLY A 148
ARG A 160
 None
None
EDO  A 267 (-3.9A)
 0.64A 1t9wA-3qnbA:
undetectable		 1t9wA-3qnbA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r0q PROBABLE PROTEIN
ARGININE
N-METHYLTRANSFERASE
4.2

(Arabidopsis
thaliana) 		no annotation 3 SER C  81
GLY C  80
ARG C  54
 SAH  C   1 ( 4.4A)
SAH  C   1 ( 3.7A)
SAH  C   1 (-2.7A)
 0.56A 1t9wA-3r0qC:
undetectable		 1t9wA-3r0qC:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rd8 FUMARATE HYDRATASE
CLASS II

(Mycolicibacterium
smegmatis) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		3 SER A 298
GLY A 297
ARG A 183
 None
 0.59A 1t9wA-3rd8A:
undetectable		 1t9wA-3rd8A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rrp PROBABLE FUMARATE
HYDRATASE FUM

(Mycobacteroides
abscessus) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		3 SER A 299
GLY A 298
ARG A 184
 None
 0.61A 1t9wA-3rrpA:
undetectable		 1t9wA-3rrpA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uto TWITCHIN

(Caenorhabditis
elegans) 		PF00041
(fn3)
PF00069
(Pkinase)
PF07679
(I-set) 		3 SER A 378
GLY A 379
ARG A 427
 None
 0.68A 1t9wA-3utoA:
2.8		 1t9wA-3utoA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zle APICAL MEMBRANE
ANTIGEN 1

(Toxoplasma
gondii) 		PF02430
(AMA-1) 		3 SER A 121
GLY A 122
ARG A 135
 None
 0.65A 1t9wA-3zleA:
undetectable		 1t9wA-3zleA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zqj UVRABC SYSTEM
PROTEIN A

(Mycobacterium
tuberculosis) 		PF00005
(ABC_tran) 		3 SER A 588
GLY A 589
ARG A   4
 None
 0.42A 1t9wA-3zqjA:
undetectable		 1t9wA-3zqjA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4apb FUMARATE HYDRATASE
CLASS II

(Mycobacterium
tuberculosis) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		3 SER A 300
GLY A 299
ARG A 185
 None
 0.63A 1t9wA-4apbA:
undetectable		 1t9wA-4apbA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4apl APICAL MEMBRANE
ANTIGEN 1

(Neospora
caninum) 		PF02430
(AMA-1) 		3 SER A  87
GLY A  88
ARG A 105
 None
 0.65A 1t9wA-4aplA:
undetectable		 1t9wA-4aplA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bb9 GLUCOKINASE
REGULATORY PROTEIN

(Homo sapiens) 		no annotation 3 SER A 183
GLY A 181
ARG A 518
 F1P  A 702 ( 4.6A)
F1P  A 702 (-3.6A)
F1P  A 702 ( 4.2A)
 0.67A 1t9wA-4bb9A:
3.0		 1t9wA-4bb9A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cp8 ALLOPHANATE
HYDROLASE

(Pseudomonas sp.
ADP) 		PF01425
(Amidase) 		3 SER A 189
GLY A 188
ARG A 328
 MLI  A1466 (-2.3A)
MLI  A1466 (-4.0A)
MLI  A1466 (-3.3A)
 0.61A 1t9wA-4cp8A:
undetectable		 1t9wA-4cp8A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4evq PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT

(Rhodopseudomonas
palustris) 		PF13458
(Peripla_BP_6) 		3 SER A 186
GLY A 187
ARG A 138
 None
None
SO4  A 402 (-3.0A)
 0.54A 1t9wA-4evqA:
undetectable		 1t9wA-4evqA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fxt UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF12866
(DUF3823) 		3 SER A  49
GLY A  48
ARG A 202
 None
 0.61A 1t9wA-4fxtA:
undetectable		 1t9wA-4fxtA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxb SORTING NEXIN-17

(Homo sapiens) 		no annotation 3 SER A 312
GLY A 311
ARG A 267
 None
 0.63A 1t9wA-4gxbA:
undetectable		 1t9wA-4gxbA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0p ACETATE KINASE

(Cryptococcus
neoformans) 		PF00871
(Acetate_kinase) 		3 SER A 223
GLY A 224
ARG A 100
 None
 0.62A 1t9wA-4h0pA:
undetectable		 1t9wA-4h0pA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hgv FUMARATE HYDRATASE
CLASS II

(Sinorhizobium
meliloti) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		3 SER A 310
GLY A 309
ARG A 196
 None
 0.67A 1t9wA-4hgvA:
undetectable		 1t9wA-4hgvA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		3 SER A 127
GLY A 128
ARG A 392
 None
 0.64A 1t9wA-4i8vA:
2.6		 1t9wA-4i8vA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb9 ANTIBODY VRC06 HEAVY
CHAIN

(Homo sapiens) 		PF07654
(C1-set) 		3 SER H   7
GLY H   8
ARG H  12
 None
 0.68A 1t9wA-4jb9H:
undetectable		 1t9wA-4jb9H:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jbe GAMMA-GLUTAMYL
PHOSPHATE REDUCTASE

(Saccharomonospora
viridis) 		PF00171
(Aldedh) 		3 SER A 209
GLY A 208
ARG A  72
 SER  A 209 (-0.0A)
GLY  A 208 (-0.0A)
ARG  A  72 ( 0.6A)
 0.52A 1t9wA-4jbeA:
undetectable		 1t9wA-4jbeA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4leb AGGLUTININ-LIKE
PROTEIN 3

(Candida
albicans) 		PF11766
(Candida_ALS_N) 		3 SER A 124
GLY A 123
ARG A 171
 None
 0.65A 1t9wA-4lebA:
undetectable		 1t9wA-4lebA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m38 PROTEIN ARGININE
N-METHYLTRANSFERASE
7

(Trypanosoma
brucei) 		PF06325
(PrmA) 		3 SER A 106
GLY A 105
ARG A  81
 SAH  A 401 (-3.3A)
SAH  A 401 ( 3.8A)
SAH  A 401 (-2.4A)
 0.61A 1t9wA-4m38A:
undetectable		 1t9wA-4m38A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mwf ENVELOPE
GLYCOPROTEIN E2
FAB AR3C HEAVY CHAIN

(Hepacivirus C;
Homo sapiens) 		PF01560
(HCV_NS1)
PF07654
(C1-set)
PF07686
(V-set) 		3 SER A 161
GLY A 162
ARG C 606
 None
 0.56A 1t9wA-4mwfA:
undetectable		 1t9wA-4mwfA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ng3 5-CARBOXYVANILLATE
DECARBOXYLASE

(Sphingomonas
paucimobilis) 		PF04909
(Amidohydro_2) 		3 SER A  53
GLY A  50
ARG A  20
 None
 0.66A 1t9wA-4ng3A:
undetectable		 1t9wA-4ng3A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pcs ALPHA-L-FUCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01120
(Alpha_L_fucos) 		3 SER A 285
GLY A 286
ARG A 271
 None
SO4  A 502 ( 4.5A)
SO4  A 502 (-3.2A)
 0.49A 1t9wA-4pcsA:
undetectable		 1t9wA-4pcsA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rhb LPS-ASSEMBLY PROTEIN
LPTD

(Escherichia
coli) 		PF04453
(OstA_C) 		3 SER A 530
GLY A 548
ARG A 480
 None
 0.68A 1t9wA-4rhbA:
undetectable		 1t9wA-4rhbA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ri6 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF1

(Populus tremula
x Populus
tremuloides) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 SER A 114
GLY A 115
ARG A  18
 None
 0.56A 1t9wA-4ri6A:
undetectable		 1t9wA-4ri6A:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ri6 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF1

(Populus tremula
x Populus
tremuloides) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 SER A 114
GLY A 115
ARG A  70
 None
None
GSH  A 500 ( 4.5A)
 0.49A 1t9wA-4ri6A:
undetectable		 1t9wA-4ri6A:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ukd URIDYLMONOPHOSPHATE/
CYTIDYLMONOPHOSPHATE
KINASE

(Dictyostelium
discoideum) 		PF00406
(ADK) 		3 SER A  17
GLY A  16
ARG A  93
 ADP  A 195 (-3.7A)
ADP  A 195 ( 3.4A)
UDP  A 196 (-2.9A)
 0.63A 1t9wA-4ukdA:
undetectable		 1t9wA-4ukdA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwa RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus) 		PF00622
(SPRY)
PF01365
(RYDR_ITPR)
PF02026
(RyR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec) 		3 SER A1085
GLY A1086
ARG A1000
 None
 0.60A 1t9wA-4uwaA:
undetectable		 1t9wA-4uwaA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wct FRUCTOSYL
AMINE:OXYGEN
OXIDOREDUCTASE

(Aspergillus
fumigatus) 		PF01266
(DAO) 		3 SER A 370
GLY A 369
ARG A 403
 None
FAD  A 500 (-3.5A)
None
 0.62A 1t9wA-4wctA:
undetectable		 1t9wA-4wctA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wse PUTATIVE POLY(A)
POLYMERASE CATALYTIC
SUBUNIT

(Acanthamoeba
polyphaga
mimivirus) 		no annotation 3 SER A 246
GLY A 247
ARG A 390
 None
 0.56A 1t9wA-4wseA:
2.7		 1t9wA-4wseA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x2r 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)METHYLIDENEAM
INO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE

(Actinomyces
urogenitalis) 		PF00977
(His_biosynth) 		3 SER A 194
GLY A 195
ARG A 137
 PO4  A 303 ( 4.2A)
PO4  A 301 (-3.6A)
PO4  A 303 (-4.0A)
 0.54A 1t9wA-4x2rA:
undetectable		 1t9wA-4x2rA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvh CARBOHYDRATE
ESTERASE FAMILY 2
(CE2)

(Chaetomium) 		PF13472
(Lipase_GDSL_2) 		3 SER A  62
GLY A  63
ARG A 104
 None
PEU  A 402 ( 4.6A)
None
 0.62A 1t9wA-4xvhA:
undetectable		 1t9wA-4xvhA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xyb FORMATE
DEHYDROGENASE

(Granulicella
mallensis) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 SER A 335
GLY A 336
ARG A 285
 NDP  A 401 (-3.1A)
NDP  A 401 (-3.3A)
AZI  A 402 ( 2.9A)
 0.53A 1t9wA-4xybA:
undetectable		 1t9wA-4xybA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yfa PROTEIN RELATED TO
PENICILLIN ACYLASE

(Acidovorax sp.
MR-S7) 		PF01804
(Penicil_amidase) 		3 SER A  63
GLY A  68
ARG C 121
 None
 0.67A 1t9wA-4yfaA:
undetectable		 1t9wA-4yfaA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yiv APICAL MEMBRANE
ANTIGEN AMA1

(Toxoplasma
gondii) 		PF02430
(AMA-1) 		3 SER A  93
GLY A  94
ARG A 111
 None
None
CO  A 506 ( 4.9A)
 0.69A 1t9wA-4yivA:
undetectable		 1t9wA-4yivA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ako TSE2
TSI2

(Pseudomonas
aeruginosa) 		no annotation 3 SER A  63
GLY A  64
ARG C 134
 None
 0.48A 1t9wA-5akoA:
3.5		 1t9wA-5akoA:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5avp L-RIBOSE ISOMERASE

(Geodermatophilus
obscurus) 		no annotation 3 SER A 245
GLY A 246
ARG A 164
 None
 0.54A 1t9wA-5avpA:
undetectable		 1t9wA-5avpA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE

(Acidovorax sp.
MR-S7) 		PF01804
(Penicil_amidase) 		3 SER A  63
GLY A  68
ARG A 323
 None
 0.67A 1t9wA-5c9iA:
undetectable		 1t9wA-5c9iA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d6b FUMARATE HYDRATASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		3 SER A 347
GLY A 346
ARG A 233
 None
 0.63A 1t9wA-5d6bA:
undetectable		 1t9wA-5d6bA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ejw CHROMOBOX PROTEIN
HOMOLOG 7

(Mus musculus) 		PF00385
(Chromo) 		3 SER A  -8
GLY A  -7
ARG A  -3
 None
5PZ  A 101 ( 3.7A)
None
 0.66A 1t9wA-5ejwA:
undetectable		 1t9wA-5ejwA:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eku ARGININE
N-METHYLTRANSFERASE,
PUTATIVE

(Trypanosoma
brucei) 		PF06325
(PrmA) 		3 SER A 106
GLY A 105
ARG A  81
 SAH  A 401 (-2.7A)
SAH  A 401 (-3.6A)
SAH  A 401 (-2.4A)
 0.66A 1t9wA-5ekuA:
undetectable		 1t9wA-5ekuA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey6 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF2

(Populus
trichocarpa) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 SER A 114
GLY A 115
ARG A  70
 None
 0.62A 1t9wA-5ey6A:
undetectable		 1t9wA-5ey6A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iv8 LPS BIOSYNTHESIS
PROTEIN

(Klebsiella
pneumoniae) 		PF04453
(OstA_C) 		3 SER A 526
GLY A 544
ARG A 479
 None
 0.65A 1t9wA-5iv8A:
undetectable		 1t9wA-5iv8A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kis RHS2

(Yersinia
entomophaga) 		no annotation 3 SER B 510
GLY B 509
ARG B 122
 None
 0.41A 1t9wA-5kisB:
undetectable		 1t9wA-5kisB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2r FUMARATE HYDRATASE

(Leishmania
major) 		PF05681
(Fumerase)
PF05683
(Fumerase_C) 		3 SER A 217
GLY A 216
ARG A 350
 SF4  A 608 ( 4.5A)
LMR  A 601 (-3.1A)
SF4  A 608 ( 4.5A)
 0.66A 1t9wA-5l2rA:
undetectable		 1t9wA-5l2rA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lw3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6

(Azotobacter
vinelandii) 		no annotation 3 SER A 228
GLY A 227
ARG A 195
 None
 0.68A 1t9wA-5lw3A:
undetectable		 1t9wA-5lw3A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m7o NITROGEN
ASSIMILATION
REGULATORY PROTEIN

(Brucella
abortus) 		PF00072
(Response_reg)
PF00158
(Sigma54_activat)
PF02954
(HTH_8) 		3 SER A  83
GLY A  84
ARG A 111
 None
 0.68A 1t9wA-5m7oA:
undetectable		 1t9wA-5m7oA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n8o DNA HELICASE I

(Escherichia
coli) 		PF07057
(TraI)
PF08751
(TrwC)
PF13604
(AAA_30) 		3 SER A 602
GLY A 603
ARG A 576
 None
 0.55A 1t9wA-5n8oA:
2.7		 1t9wA-5n8oA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nqf APICAL MEMBRANE
ANTIGEN 1

(Plasmodium
falciparum) 		PF02430
(AMA-1) 		3 SER A 125
GLY A 126
ARG A 143
 SER  A 125 ( 0.0A)
GLY  A 126 ( 0.0A)
ARG  A 143 ( 0.6A)
 0.67A 1t9wA-5nqfA:
undetectable		 1t9wA-5nqfA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5or7 CAPSID PROTEIN

(Norwalk virus) 		no annotation 3 SER A 282
GLY A 283
ARG A 392
 None
 0.65A 1t9wA-5or7A:
undetectable		 1t9wA-5or7A:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tbf TRANSLATION
ELONGATION FACTOR

(Vibrio cholerae) 		PF11826
(DUF3346) 		3 SER A 206
GLY A 207
ARG A 301
 None
 0.58A 1t9wA-5tbfA:
2.3		 1t9wA-5tbfA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue1 5'-METHYLTHIOADENOSI
NE/S-ADENOSYLHOMOCYS
TEINE NUCLEOSIDASE

(Aliivibrio
fischeri) 		PF01048
(PNP_UDP_1) 		3 SER A  48
GLY A  49
ARG A 194
 None
None
TRS  A 302 (-3.4A)
 0.64A 1t9wA-5ue1A:
undetectable		 1t9wA-5ue1A:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7a ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT

(Oryctolagus
cuniculus) 		no annotation 3 SER B 411
GLY B 410
ARG B 217
 None
 0.64A 1t9wA-5w7aB:
undetectable		 1t9wA-5w7aB:
5.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xru ADENYLATE KINASE

(Notothenia
coriiceps) 		no annotation 3 SER A  19
GLY A  18
ARG A  97
 AP5  A 201 (-3.5A)
AP5  A 201 (-3.5A)
AP5  A 201 (-3.1A)
 0.42A 1t9wA-5xruA:
undetectable		 1t9wA-5xruA:
5.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yp3 DIPEPTIDYL
AMINOPEPTIDASE 4

(Pseudoxanthomonas
mexicana) 		no annotation 3 SER A 111
GLY A 112
ARG A  61
 None
 0.50A 1t9wA-5yp3A:
undetectable		 1t9wA-5yp3A:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zgb PSAF

(Cyanidioschyzon
merolae) 		no annotation 3 SER F 170
GLY F 171
ARG F 126
 None
 0.58A 1t9wA-5zgbF:
2.8		 1t9wA-5zgbF:
5.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ay4 CYP51, STEROL
14ALPHA-DEMETHYLASE

(Naegleria
fowleri) 		no annotation 3 SER A  49
GLY A  48
ARG A  39
 None
 0.63A 1t9wA-6ay4A:
2.6		 1t9wA-6ay4A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6az1 RIBOSOMAL PROTEIN
S4E

(Leishmania
donovani) 		no annotation 3 SER E 211
GLY E 212
ARG E 188
 None
 0.61A 1t9wA-6az1E:
undetectable		 1t9wA-6az1E:
4.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c6y JC57-14 HEAVY CHAIN

(Macaca mulatta) 		no annotation 3 SER A  53
GLY A  54
ARG A  50
 None
 0.33A 1t9wA-6c6yA:
undetectable		 1t9wA-6c6yA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e29 -

(-) 		no annotation 3 SER D  24
GLY D  25
ARG D  63
 None
 0.60A 1t9wA-6e29D:
undetectable		 1t9wA-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gdt -

(-) 		no annotation 3 SER A 435
GLY A 436
ARG A 543
 None
 0.64A 1t9wA-6gdtA:
undetectable		 1t9wA-6gdtA:
undetectable