SIMILAR PATTERNS OF AMINO ACIDS FOR 1T87_B_CAMB2422_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9n U2A'

(Homo sapiens) 		PF14580
(LRR_9) 		4 PHE A  60
LEU A  93
VAL A  71
ILE A  34
 None
 0.97A 1t87B-1a9nA:
0.0		 1t87B-1a9nA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aip ELONGATION FACTOR TS

(Thermus
thermophilus) 		PF00889
(EF_TS) 		4 LEU C 157
VAL C 169
VAL C  74
ILE C 100
 None
 0.98A 1t87B-1aipC:
0.0		 1t87B-1aipC:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1avq LAMBDA EXONUCLEASE

(Escherichia
virus Lambda) 		PF09588
(YqaJ) 		4 TYR A 107
LEU A  27
VAL A  14
ILE A   5
 None
 0.96A 1t87B-1avqA:
0.0		 1t87B-1avqA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)

(Homo sapiens) 		PF00168
(C2)
PF01735
(PLA2_B) 		4 PHE A 291
LEU A 405
VAL A 272
ILE A 294
 None
 0.87A 1t87B-1cjyA:
0.0		 1t87B-1cjyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cyg CYCLODEXTRIN
GLUCANOTRANSFERASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		4 THR A 318
LEU A 345
VAL A 344
ILE A 303
 None
 0.98A 1t87B-1cygA:
0.0		 1t87B-1cygA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dju AROMATIC
AMINOTRANSFERASE

(Pyrococcus
horikoshii) 		PF00155
(Aminotran_1_2) 		4 THR A 161
LEU A 194
VAL A 138
ILE A 116
 None
 0.81A 1t87B-1djuA:
0.0		 1t87B-1djuA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dwu RIBOSOMAL PROTEIN L1

(Methanothermococcus
thermolithotrophicus) 		PF00687
(Ribosomal_L1) 		4 THR A 154
LEU A  32
VAL A 196
ILE A 181
 None
 0.96A 1t87B-1dwuA:
undetectable		 1t87B-1dwuA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ejb LUMAZINE SYNTHASE

(Saccharomyces
cerevisiae) 		PF00885
(DMRL_synthase) 		4 THR A 105
LEU A 124
VAL A  57
ILE A  22
 None
 0.92A 1t87B-1ejbA:
0.0		 1t87B-1ejbA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gae D-GLYCERALDEHYDE-3-P
HOSPHATE
DEHYDROGENASE

(Escherichia
coli) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 PHE O   8
VAL O  66
VAL O  73
ILE O  30
 None
 0.92A 1t87B-1gaeO:
0.0		 1t87B-1gaeO:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq7 PROCLAVAMINATE
AMIDINO HYDROLASE

(Streptomyces
clavuligerus) 		PF00491
(Arginase) 		4 LEU A 261
VAL A 260
VAL A 277
ILE A 236
 None
 0.89A 1t87B-1gq7A:
undetectable		 1t87B-1gq7A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7o 4-HYDROXYPHENYLACETA
TE DEGRADATION
BIFUNCTIONAL
ISOMERASE/DECARBOXYL
ASE

(Escherichia
coli) 		PF01557
(FAA_hydrolase) 		4 THR A 393
LEU A 368
VAL A 299
ILE A 376
 None
 0.90A 1t87B-1i7oA:
undetectable		 1t87B-1i7oA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsw L-ASPARTATE
AMMONIA-LYASE

(Escherichia
coli) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 PHE A 457
LEU A 448
VAL A 442
ILE A 411
 None
 0.93A 1t87B-1jswA:
undetectable		 1t87B-1jswA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lfp HYPOTHETICAL PROTEIN
AQ_1575

(Aquifex
aeolicus) 		PF01709
(Transcrip_reg) 		4 PHE A 117
LEU A 222
VAL A 234
VAL A 130
 None
 0.96A 1t87B-1lfpA:
undetectable		 1t87B-1lfpA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqq ALPHA-D-GLUCURONIDAS
E

(Geobacillus
stearothermophilus) 		PF03648
(Glyco_hydro_67N)
PF07477
(Glyco_hydro_67C)
PF07488
(Glyco_hydro_67M) 		4 PHE A 663
VAL A 518
VAL A 604
ILE A 608
 None
 0.87A 1t87B-1mqqA:
undetectable		 1t87B-1mqqA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nd7 WW DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A 831
LEU A 847
VAL A 850
ILE A 875
 None
 0.80A 1t87B-1nd7A:
undetectable		 1t87B-1nd7A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8k EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2
SUBUNIT 1

(Homo sapiens) 		PF00575
(S1)
PF07541
(EIF_2_alpha) 		4 THR A 133
LEU A 129
VAL A 114
ILE A 179
 None
 0.93A 1t87B-1q8kA:
undetectable		 1t87B-1q8kA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwg (2R)-PHOSPHO-3-SULFO
LACTATE SYNTHASE

(Methanocaldococcus
jannaschii) 		PF02679
(ComA) 		4 PHE A 219
LEU A 178
VAL A 197
ILE A 199
 None
 0.89A 1t87B-1qwgA:
undetectable		 1t87B-1qwgA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sgv TRNA PSEUDOURIDINE
SYNTHASE B

(Mycobacterium
tuberculosis) 		PF01509
(TruB_N)
PF09142
(TruB_C)
PF16198
(TruB_C_2) 		4 THR A   4
LEU A 224
VAL A   9
ILE A  29
 None
 0.98A 1t87B-1sgvA:
undetectable		 1t87B-1sgvA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ss4 GLYOXALASE FAMILY
PROTEIN

(Bacillus cereus) 		PF13669
(Glyoxalase_4) 		4 PHE A  26
VAL A  16
VAL A  12
ILE A  69
 None
 0.98A 1t87B-1ss4A:
undetectable		 1t87B-1ss4A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t8q GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE,
PERIPLASMIC

(Escherichia
coli) 		PF03009
(GDPD) 		4 PHE A 148
VAL A 205
VAL A 155
ILE A 152
 None
 0.89A 1t87B-1t8qA:
undetectable		 1t87B-1t8qA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tfe ELONGATION FACTOR TS

(Thermus
thermophilus) 		PF00889
(EF_TS) 		4 LEU A 157
VAL A 169
VAL A  74
ILE A 100
 None
 0.98A 1t87B-1tfeA:
undetectable		 1t87B-1tfeA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqx D-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE,
PUTATIVE

(Plasmodium
falciparum) 		PF00834
(Ribul_P_3_epim) 		4 LEU A  13
VAL A  12
VAL A  54
ILE A  55
 None
 0.91A 1t87B-1tqxA:
undetectable		 1t87B-1tqxA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tyd TYROSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophilus) 		PF00579
(tRNA-synt_1b) 		5 PHE E 231
THR E 258
LEU E 298
VAL E 302
ILE E  46
 None
 1.33A 1t87B-1tydE:
undetectable		 1t87B-1tydE:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1um2 ENDONUCLEASE PI-SCEI

(Saccharomyces
cerevisiae) 		PF05203
(Hom_end_hint)
PF05204
(Hom_end) 		4 LEU A 719
VAL A 320
VAL A 291
ILE A 301
 None
 0.96A 1t87B-1um2A:
undetectable		 1t87B-1um2A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbm TYROSYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF00579
(tRNA-synt_1b) 		5 PHE A 236
THR A 263
LEU A 303
VAL A 307
VAL A 244
 None
 1.37A 1t87B-1vbmA:
undetectable		 1t87B-1vbmA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vdk FUMARATE HYDRATASE
CLASS II

(Thermus
thermophilus) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 THR A 170
VAL A 380
VAL A 295
ILE A 291
 None
 0.91A 1t87B-1vdkA:
undetectable		 1t87B-1vdkA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhi EPSTEIN BARR VIRUS
NUCLEAR ANTIGEN-1

(Human
gammaherpesvirus
4) 		PF02905
(EBV-NA1) 		4 THR A 524
LEU A 485
VAL A 595
ILE A 593
 None
 0.79A 1t87B-1vhiA:
undetectable		 1t87B-1vhiA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vmb 30S RIBOSOMAL
PROTEIN S6

(Thermotoga
maritima) 		PF01250
(Ribosomal_S6) 		4 PHE A  71
THR A  96
VAL A  31
ILE A  35
 None
 0.97A 1t87B-1vmbA:
undetectable		 1t87B-1vmbA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w66 LIPOYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF03099
(BPL_LplA_LipB) 		4 THR A 155
LEU A  96
VAL A 207
ILE A  12
 None
 0.95A 1t87B-1w66A:
undetectable		 1t87B-1w66A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xc3 PUTATIVE
FRUCTOKINASE

(Bacillus
subtilis) 		PF00480
(ROK) 		4 PHE A  86
VAL A  41
VAL A  98
ILE A  55
 None
 0.94A 1t87B-1xc3A:
undetectable		 1t87B-1xc3A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygp YEAST GLYCOGEN
PHOSPHORYLASE

(Saccharomyces
cerevisiae) 		PF00343
(Phosphorylase) 		4 THR A 506
LEU A 521
VAL A 802
VAL A 537
 None
 0.79A 1t87B-1ygpA:
undetectable		 1t87B-1ygpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yyr TRICHODIENE SYNTHASE

(Fusarium
sporotrichioides) 		PF06330
(TRI5) 		4 TYR A  93
LEU A 150
VAL A 138
VAL A  81
 SAZ  A 709 (-4.9A)
None
None
None
 0.91A 1t87B-1yyrA:
undetectable		 1t87B-1yyrA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvd SMAD UBIQUITINATION
REGULATORY FACTOR 2

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A 656
LEU A 672
VAL A 675
ILE A 700
 None
 0.81A 1t87B-1zvdA:
undetectable		 1t87B-1zvdA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2awa DNA POLYMERASE III,
BETA CHAIN

(Streptococcus
pneumoniae) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		5 PHE A  11
LEU A  77
VAL A  34
VAL A  38
ILE A  43
 None
 1.16A 1t87B-2awaA:
undetectable		 1t87B-2awaA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7h HEMOGLOBIN ALPHA
CHAIN

(Cerdocyon thous) 		PF00042
(Globin) 		4 PHE A  43
THR A  32
VAL A  62
VAL A  93
 HEM  A 200 (-3.5A)
None
HEM  A 200 ( 3.8A)
HEM  A 200 (-4.3A)
 0.97A 1t87B-2b7hA:
undetectable		 1t87B-2b7hA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ctf VIGILIN

(Homo sapiens) 		PF00013
(KH_1) 		4 PHE A  63
LEU A  72
VAL A  90
ILE A  41
 None
 0.99A 1t87B-2ctfA:
undetectable		 1t87B-2ctfA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7u GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE

(Thermus
thermophilus) 		PF00202
(Aminotran_3) 		5 TYR A  57
THR A 416
LEU A 387
VAL A 350
ILE A 357
 None
 1.31A 1t87B-2e7uA:
undetectable		 1t87B-2e7uA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eeo ASPARTATE
1-DECARBOXYLASE

(Thermus
thermophilus) 		PF02261
(Asp_decarbox) 		4 THR B  57
LEU B  55
VAL B  79
ILE B  69
 FUM  B 501 ( 3.6A)
None
None
None
 0.94A 1t87B-2eeoB:
undetectable		 1t87B-2eeoB:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2egg SHIKIMATE
5-DEHYDROGENASE

(Geobacillus
kaustophilus) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 THR A 246
LEU A 249
VAL A 236
ILE A 147
 None
 0.97A 1t87B-2eggA:
undetectable		 1t87B-2eggA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ep7 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Aquifex
aeolicus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 PHE A  10
VAL A  67
VAL A  74
ILE A  32
 None
 0.98A 1t87B-2ep7A:
undetectable		 1t87B-2ep7A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f3o PYRUVATE
FORMATE-LYASE 2

(Archaeoglobus
fulgidus) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		4 PHE A  78
LEU A  47
VAL A  50
ILE A  76
 None
 0.97A 1t87B-2f3oA:
undetectable		 1t87B-2f3oA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8t ARGONAUTE PROTEIN

(Aquifex
aeolicus) 		PF02171
(Piwi) 		4 THR A 678
LEU A 662
VAL A 643
ILE A 641
 None
 0.93A 1t87B-2f8tA:
undetectable		 1t87B-2f8tA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h3g BIOSYNTHETIC PROTEIN

(Bacillus
anthracis) 		PF03309
(Pan_kinase) 		4 PHE X 130
THR X 151
VAL X 204
ILE X 227
 None
 0.91A 1t87B-2h3gX:
undetectable		 1t87B-2h3gX:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hey TUMOR NECROSIS
FACTOR LIGAND
SUPERFAMILY MEMBER 4

(Mus musculus) 		no annotation 4 PHE F 110
VAL F 156
VAL F  67
ILE F 168
 None
 0.99A 1t87B-2heyF:
undetectable		 1t87B-2heyF:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2liv LEUCINE

(Escherichia
coli) 		PF13458
(Peripla_BP_6) 		4 PHE A 196
VAL A 331
VAL A 158
ILE A 132
 None
 0.98A 1t87B-2livA:
undetectable		 1t87B-2livA:
24.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		4 PHE A  87
TYR A  96
LEU A 244
VAL A 396
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-4.5A)
None
 0.67A 1t87B-2m56A:
69.9		 1t87B-2m56A:
99.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		7 PHE A  87
TYR A  96
THR A 101
LEU A 244
VAL A 247
VAL A 295
ILE A 395
 CAM  A 502 (-4.6A)
CAM  A 502 (-4.5A)
HEM  A 501 (-2.9A)
HEM  A 501 (-4.5A)
None
HEM  A 501 (-4.6A)
None
 0.29A 1t87B-2m56A:
69.9		 1t87B-2m56A:
99.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ntt STAPHYLOCOCCAL
ENTEROTOXIN K

(Staphylococcus
aureus) 		PF02876
(Stap_Strp_tox_C) 		4 PHE A 168
LEU A 180
VAL A 113
ILE A 125
 None
 0.94A 1t87B-2nttA:
undetectable		 1t87B-2nttA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p6r AFUHEL308 HELICASE

(Archaeoglobus
fulgidus) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 LEU A 505
VAL A 616
VAL A 611
ILE A 607
 None
 0.89A 1t87B-2p6rA:
undetectable		 1t87B-2p6rA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2phc UNCHARACTERIZED
PROTEIN PH0987

(Pyrococcus
horikoshii) 		PF02682
(CT_C_D) 		4 THR B 168
VAL B 206
VAL B  90
ILE B 185
 None
 0.93A 1t87B-2phcB:
undetectable		 1t87B-2phcB:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pqv MUTT/NUDIX FAMILY
PROTEIN

(Streptococcus
pneumoniae) 		PF00293
(NUDIX) 		4 THR A  40
LEU A 128
VAL A 131
VAL A  76
 None
 0.93A 1t87B-2pqvA:
undetectable		 1t87B-2pqvA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pz0 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Caldanaerobacter
subterraneus) 		PF03009
(GDPD) 		4 LEU A  55
VAL A  47
VAL A 147
ILE A 149
 None
 0.99A 1t87B-2pz0A:
undetectable		 1t87B-2pz0A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rsv SERINE/THREONINE-PRO
TEIN KINASE VRK1

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE A 290
LEU A 155
VAL A 154
ILE A 252
 None
 0.85A 1t87B-2rsvA:
undetectable		 1t87B-2rsvA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ts1 TYROSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophilus) 		PF00579
(tRNA-synt_1b) 		5 PHE A 231
THR A 258
LEU A 298
VAL A 302
ILE A  46
 None
 1.33A 1t87B-2ts1A:
undetectable		 1t87B-2ts1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v84 SPERMIDINE/PUTRESCIN
E ABC TRANSPORTER,
PERIPLASMIC BINDING
PROTEIN

(Treponema
pallidum) 		PF13416
(SBP_bac_8) 		4 PHE A 242
TYR A 109
THR A  18
ILE A 258
 None
 0.94A 1t87B-2v84A:
undetectable		 1t87B-2v84A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wan PULLULANASE

(Bacillus
acidopullulyticus) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 PHE A 699
THR A 916
VAL A 714
ILE A 710
 None
 0.92A 1t87B-2wanA:
undetectable		 1t87B-2wanA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xdq LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Thermosynechococcus
elongatus) 		PF00148
(Oxidored_nitro) 		4 PHE A 421
LEU A 436
VAL A 320
ILE A 399
 None
 0.97A 1t87B-2xdqA:
undetectable		 1t87B-2xdqA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yxl 450AA LONG
HYPOTHETICAL FMU
PROTEIN

(Pyrococcus
horikoshii) 		PF01189
(Methyltr_RsmB-F)
PF17125
(Methyltr_RsmF_N) 		4 LEU A  49
VAL A  52
VAL A  92
ILE A  96
 None
 0.89A 1t87B-2yxlA:
undetectable		 1t87B-2yxlA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b1e BETAC-S LYASE

(Streptococcus
anginosus) 		PF00155
(Aminotran_1_2) 		4 LEU A 313
VAL A 383
VAL A 348
ILE A 378
 None
 0.98A 1t87B-3b1eA:
undetectable		 1t87B-3b1eA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b89 16S RRNA METHYLASE

(Escherichia
coli) 		PF07091
(FmrO) 		4 THR A  84
VAL A  74
VAL A 139
ILE A 140
 None
 0.83A 1t87B-3b89A:
undetectable		 1t87B-3b89A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9t TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Methylobacillus
flagellatus) 		PF03069
(FmdA_AmdA) 		4 TYR A 227
LEU A 279
VAL A 278
VAL A 223
 None
 0.92A 1t87B-3b9tA:
undetectable		 1t87B-3b9tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dbx CD1-2 ANTIGEN

(Gallus gallus) 		PF07654
(C1-set)
PF16497
(MHC_I_3) 		4 PHE A 214
LEU A 242
VAL A 221
ILE A 219
 None
 0.99A 1t87B-3dbxA:
undetectable		 1t87B-3dbxA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920

(Cryptosporidium
parvum) 		PF00069
(Pkinase) 		4 PHE A 157
THR A  48
LEU A  52
ILE A  38
 None
 0.83A 1t87B-3dfaA:
undetectable		 1t87B-3dfaA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dqq PUTATIVE TRNA
SYNTHASE

(Salmonella
enterica) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		4 PHE A  11
THR A 368
LEU A 398
VAL A 389
 None
 0.94A 1t87B-3dqqA:
undetectable		 1t87B-3dqqA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzz PUTATIVE PYRIDOXAL
5'-PHOSPHATE-DEPENDE
NT C-S LYASE

(Lactobacillus
delbrueckii) 		PF00155
(Aminotran_1_2) 		4 PHE A 337
VAL A 309
VAL A 325
ILE A 327
 None
 0.90A 1t87B-3dzzA:
undetectable		 1t87B-3dzzA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fza GLUTAREDOXIN

(Populus tremula
x Populus
tremuloides) 		PF00462
(Glutaredoxin) 		4 LEU A  42
VAL A  44
VAL A  77
ILE A  79
 None
 0.97A 1t87B-3fzaA:
undetectable		 1t87B-3fzaA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hee RIBOSE-5-PHOSPHATE
ISOMERASE

(Ruminiclostridium
thermocellum) 		PF02502
(LacAB_rpiB) 		4 LEU A 117
VAL A 120
VAL A  29
ILE A   5
 None
 0.91A 1t87B-3heeA:
undetectable		 1t87B-3heeA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hri HISTIDYL-TRNA
SYNTHETASE

(Trypanosoma
brucei) 		PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His) 		4 PHE A 361
VAL A 204
VAL A 365
ILE A 366
 None
 0.99A 1t87B-3hriA:
undetectable		 1t87B-3hriA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ip1 ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Thermotoga
maritima) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 241
VAL A 239
VAL A 202
ILE A 230
 None
 0.93A 1t87B-3ip1A:
undetectable		 1t87B-3ip1A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwh RHODANESE-LIKE
DOMAIN PROTEIN

(Staphylococcus
aureus) 		PF00581
(Rhodanese) 		4 LEU A  13
VAL A  19
VAL A  86
ILE A   4
 None
 0.97A 1t87B-3iwhA:
undetectable		 1t87B-3iwhA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j7y BL21

(Homo sapiens) 		PF00829
(Ribosomal_L21p) 		4 LEU S 149
VAL S 136
VAL S  83
ILE S  87
 None
 0.90A 1t87B-3j7yS:
undetectable		 1t87B-3j7yS:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j83 ESX-1
SECRETION-ASSOCIATED
PROTEIN ESPB

(Mycobacterium
tuberculosis) 		no annotation 4 LEU A 270
VAL A 212
VAL A  32
ILE A  34
 None
 0.76A 1t87B-3j83A:
undetectable		 1t87B-3j83A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9q SHEATH

(Pseudomonas
aeruginosa) 		PF04984
(Phage_sheath_1)
PF17482
(Phage_sheath_1C) 		4 THR A 211
LEU A 207
VAL A 281
ILE A 153
 None
 0.92A 1t87B-3j9qA:
undetectable		 1t87B-3j9qA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jyy LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE

(Enterococcus
faecium) 		no annotation 4 PHE A  92
LEU A  14
VAL A  11
VAL A  80
 None
 0.98A 1t87B-3jyyA:
undetectable		 1t87B-3jyyA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfo NUCLEOPORIN NUP133

(Saccharomyces
cerevisiae) 		no annotation 4 TYR A1094
LEU A1037
VAL A 983
ILE A1109
 None
 0.84A 1t87B-3kfoA:
undetectable		 1t87B-3kfoA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3krm INSULIN-LIKE GROWTH
FACTOR 2
MRNA-BINDING PROTEIN
1

(Homo sapiens) 		PF00013
(KH_1) 		4 LEU A 513
VAL A 521
VAL A 494
ILE A 492
 None
 0.86A 1t87B-3krmA:
undetectable		 1t87B-3krmA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE

(Xanthomonas
campestris) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 PHE A  81
VAL A 111
VAL A  98
ILE A  95
 None
 0.74A 1t87B-3l06A:
undetectable		 1t87B-3l06A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ld2 PUTATIVE
ACETYLTRANSFERASE

(Streptococcus
mutans) 		PF00583
(Acetyltransf_1) 		4 PHE A  79
LEU A 129
VAL A 115
ILE A 113
 None
 0.93A 1t87B-3ld2A:
undetectable		 1t87B-3ld2A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldu PUTATIVE METHYLASE

(Clostridioides
difficile) 		PF01170
(UPF0020)
PF02926
(THUMP) 		4 THR A  41
LEU A   6
VAL A 241
ILE A 237
 None
 0.94A 1t87B-3lduA:
undetectable		 1t87B-3lduA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3luq SENSOR PROTEIN

(Geobacter
sulfurreducens) 		PF08448
(PAS_4) 		4 PHE A 105
TYR A 111
LEU A 124
ILE A 194
 None
 0.96A 1t87B-3luqA:
undetectable		 1t87B-3luqA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1l 3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE

(Mycobacterium
tuberculosis) 		PF13561
(adh_short_C2) 		5 PHE A 431
TYR A 430
THR A 177
LEU A 181
VAL A 189
 None
 1.10A 1t87B-3m1lA:
undetectable		 1t87B-3m1lA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m65 ATP-DEPENDENT
PROTEASE LA 1

(Bacillus
subtilis) 		PF02190
(LON_substr_bdg) 		4 LEU A 191
VAL A 194
VAL A 154
ILE A 166
 None
 0.98A 1t87B-3m65A:
undetectable		 1t87B-3m65A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n7t MACROPHAGE BINDING
PROTEIN

(Coccidioides
immitis) 		PF01965
(DJ-1_PfpI) 		4 PHE A  45
LEU A   4
VAL A 241
ILE A 234
 None
 0.88A 1t87B-3n7tA:
undetectable		 1t87B-3n7tA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzu PHOSPHATIDYLINOSITOL
-4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd) 		4 THR A 399
LEU A 414
VAL A 363
ILE A 516
 None
 0.98A 1t87B-3nzuA:
undetectable		 1t87B-3nzuA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odt PROTEIN DOA1

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 LEU A  69
VAL A  60
VAL A 284
ILE A 276
 None
 0.96A 1t87B-3odtA:
undetectable		 1t87B-3odtA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p3q MMOQ

(Methylococcus
capsulatus) 		PF08668
(HDOD) 		4 THR A  68
LEU A  72
VAL A  86
ILE A  90
 None
 0.86A 1t87B-3p3qA:
undetectable		 1t87B-3p3qA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvl MYOSIN VIIA ISOFORM
1

(Mus musculus) 		PF00784
(MyTH4) 		4 PHE A1532
LEU A1511
VAL A1498
VAL A1489
 None
None
None
GOL  A   1 ( 4.7A)
 0.99A 1t87B-3pvlA:
undetectable		 1t87B-3pvlA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pz6 LEUCYL-TRNA
SYNTHETASE

(Giardia
intestinalis) 		PF00133
(tRNA-synt_1) 		4 LEU A 268
VAL A 407
VAL A 350
ILE A 433
 None
 0.98A 1t87B-3pz6A:
undetectable		 1t87B-3pz6A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qj4 RENALASE

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		4 LEU A 335
VAL A 334
VAL A   4
ILE A   6
 None
 0.95A 1t87B-3qj4A:
undetectable		 1t87B-3qj4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rim TRANSKETOLASE

(Mycobacterium
tuberculosis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 THR A 561
LEU A 573
VAL A 600
VAL A 555
 None
 0.89A 1t87B-3rimA:
undetectable		 1t87B-3rimA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6h N-ACETYLGLUTAMATE
KINASE /
N-ACETYLGLUTAMATE
SYNTHASE

(Maricaulis
maris) 		PF00696
(AA_kinase)
PF04768
(NAT) 		5 TYR A 324
THR A 436
LEU A 437
VAL A 312
ILE A 344
 None
GLU  A 501 (-3.8A)
GLU  A 501 ( 4.1A)
None
None
 1.27A 1t87B-3s6hA:
undetectable		 1t87B-3s6hA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3skv SSFX3

(Streptomyces
sp. SF2575) 		PF13472
(Lipase_GDSL_2) 		4 THR A  71
LEU A 152
VAL A 150
VAL A 103
 None
 0.99A 1t87B-3skvA:
undetectable		 1t87B-3skvA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3smt HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3

(Homo sapiens) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		4 THR A 199
VAL A 193
VAL A 321
ILE A 322
 None
None
None
UNX  A 502 ( 4.8A)
 0.88A 1t87B-3smtA:
undetectable		 1t87B-3smtA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sth GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Toxoplasma
gondii) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 PHE A  10
VAL A  68
VAL A  75
ILE A  32
 None
 0.99A 1t87B-3sthA:
undetectable		 1t87B-3sthA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr9 DIHYDROPTEROATE
SYNTHASE

(Coxiella
burnetii) 		PF00809
(Pterin_bind) 		4 PHE A 202
LEU A 172
VAL A 175
VAL A 231
 None
 0.87A 1t87B-3tr9A:
undetectable		 1t87B-3tr9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umf ADENYLATE KINASE

(Schistosoma
mansoni) 		PF00406
(ADK) 		4 PHE A  13
TYR A  96
LEU A  74
VAL A 110
 None
 0.87A 1t87B-3umfA:
undetectable		 1t87B-3umfA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vor CFA/III PILIN

(Escherichia
coli) 		PF05946
(TcpA) 		4 THR A 169
LEU A 150
VAL A 120
ILE A 109
 None
 0.99A 1t87B-3vorA:
undetectable		 1t87B-3vorA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vwa CYTOPLASMIC EXPORT
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 PHE A 389
LEU A 405
VAL A 412
ILE A 411
 None
 0.96A 1t87B-3vwaA:
undetectable		 1t87B-3vwaA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wia NITRITE REDUCTASE

(Geobacillus
kaustophilus) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A  73
VAL A 151
VAL A 278
ILE A 232
 None
 0.94A 1t87B-3wiaA:
undetectable		 1t87B-3wiaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wkq NITRITE REDUCTASE

(Geobacillus
thermodenitrificans) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A  73
VAL A 151
VAL A 278
ILE A 232
 MPD  A 419 ( 4.7A)
None
None
None
 0.92A 1t87B-3wkqA:
undetectable		 1t87B-3wkqA:
22.25