SIMILAR PATTERNS OF AMINO ACIDS FOR 1T7J_A_478A200_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ak0 | P1 NUCLEASE (Penicilliumcitrinum) |
PF02265(S1-P1_nuclease) | 4 | ASP A 127ALA A 212GLY A 252ILE A 118 | None | 0.83A | 1t7jB-1ak0A:undetectable | 1t7jB-1ak0A:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cf2 | PROTEIN(GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE) (Methanothermusfervidus) |
no annotation | 4 | ASP P 235VAL P 239GLY P 157THR P 148 | None | 0.74A | 1t7jB-1cf2P:undetectable | 1t7jB-1cf2P:15.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cfa | COMPLEMENT 5ASEMI-SYNTHETICANTAGONIST (Homo sapiens) |
PF01821(ANATO) | 4 | ALA A 50VAL A 17GLY A 44ILE A 41 | None | 0.80A | 1t7jB-1cfaA:undetectable | 1t7jB-1cfaA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cp2 | NITROGENASE IRONPROTEIN (Clostridiumpasteurianum) |
PF00142(Fer4_NifH) | 4 | ASP A 38ALA A 41ILE A 12THR A 18 | None | 0.78A | 1t7jB-1cp2A:undetectable | 1t7jB-1cp2A:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2e | ELONGATION FACTOR TU(EF-TU) (Bos taurus) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | ASP A 132GLY A 61ILE A 148THR A 161 | None | 0.68A | 1t7jB-1d2eA:undetectable | 1t7jB-1d2eA:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e32 | P97 (Mus musculus) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2) | 4 | ASP A 120VAL A 123GLY A 186THR A 127 | None | 0.69A | 1t7jB-1e32A:2.9 | 1t7jB-1e32A:13.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezv | UBIQUINOL-CYTOCHROMEC REDUCTASE COMPLEXCORE PROTEIN I (Saccharomycescerevisiae) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 4 | ASP A 113GLY A 51ILE A 104THR A 47 | None | 0.84A | 1t7jB-1ezvA:undetectable | 1t7jB-1ezvA:11.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hpl | LIPASE (Equus caballus) |
PF00151(Lipase)PF01477(PLAT) | 4 | ALA A 161VAL A 124GLY A 150ILE A 149 | None | 0.80A | 1t7jB-1hplA:undetectable | 1t7jB-1hplA:13.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 25ALA A 28ASP A 30VAL A 32 | A79 A 800 (-2.7A)A79 A 800 (-3.1A)A79 A 800 ( 4.9A)A79 A 800 ( 4.4A) | 0.51A | 1t7jB-1hvcA:14.4 | 1t7jB-1hvcA:46.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 25ALA A 28ASP A 30VAL A 32 | A79 A 800 (-2.8A)A79 A 800 (-3.2A)A79 A 800 ( 4.7A)A79 A 800 ( 4.3A) | 0.48A | 1t7jB-1hvcA:14.4 | 1t7jB-1hvcA:46.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 25ALA A 28VAL A 32GLY A 49ILE A 50 | A79 A 800 (-2.7A)A79 A 800 (-3.1A)A79 A 800 ( 4.4A)A79 A 800 ( 3.7A)A79 A 800 (-3.8A) | 0.39A | 1t7jB-1hvcA:14.4 | 1t7jB-1hvcA:46.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 25ALA A 28VAL A 32GLY A 49ILE A 50 | A79 A 800 (-2.8A)A79 A 800 (-3.2A)A79 A 800 ( 4.3A)A79 A 800 (-3.4A)A79 A 800 ( 4.0A) | 0.48A | 1t7jB-1hvcA:14.4 | 1t7jB-1hvcA:46.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lpb | LIPASE (Homo sapiens) |
PF00151(Lipase)PF01477(PLAT) | 4 | ALA B 161VAL B 124GLY B 150ILE B 149 | None | 0.78A | 1t7jB-1lpbB:undetectable | 1t7jB-1lpbB:12.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o9j | ALDEHYDEDEHYDROGENASE,CYTOSOLIC 1 (Elephantulusedwardii) |
PF00171(Aldedh) | 4 | ALA A 194GLY A 229ILE A 232THR A 244 | NAD A1501 (-4.1A)NAD A1501 (-3.5A)NoneNAD A1501 (-4.1A) | 0.84A | 1t7jB-1o9jA:undetectable | 1t7jB-1o9jA:11.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p1v | SUPEROXIDE DISMUTASE[CU-ZN] (Homo sapiens) |
PF00080(Sod_Cu) | 4 | ASP A 96VAL A 87GLY A 16ILE A 17 | None | 0.74A | 1t7jB-1p1vA:undetectable | 1t7jB-1p1vA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pdz | ENOLASE (Homarusgammarus) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | ALA A 247ASP A 320ILE A 256THR A 304 | None | 0.82A | 1t7jB-1pdzA:undetectable | 1t7jB-1pdzA:13.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1q9p | HIV-1 PROTEASE (Homo sapiens) |
PF00077(RVP) | 4 | ASP A 25ALA A 28ASP A 30VAL A 32 | None | 0.45A | 1t7jB-1q9pA:10.6 | 1t7jB-1q9pA:91.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qdl | PROTEIN(ANTHRANILATESYNTHASE(TRPG-SUBUNIT)) (Sulfolobussolfataricus) |
PF00117(GATase) | 4 | VAL B 195GLY B 82ILE B 51THR B 78 | None | 0.81A | 1t7jB-1qdlB:undetectable | 1t7jB-1qdlB:19.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1siv | SIV PROTEASE (Simianimmunodeficiencyvirus) |
PF00077(RVP) | 4 | ASP A 25ALA A 28GLY A 49ILE A 50 | None | 0.32A | 1t7jB-1sivA:18.3 | 1t7jB-1sivA:49.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tki | TITIN (Homo sapiens) |
PF00069(Pkinase) | 4 | ASP A 61VAL A 65GLY A 36ILE A 37 | None | 0.77A | 1t7jB-1tkiA:undetectable | 1t7jB-1tkiA:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 2 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | ALA B 384ASP B 292GLY B 252ILE B 5 | None | 0.67A | 1t7jB-1tqyB:undetectable | 1t7jB-1tqyB:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7w | COENZYME ABIOSYNTHESISBIFUNCTIONAL PROTEINCOABC (Escherichiacoli) |
PF04127(DFP) | 4 | ASP A 309VAL A 314GLY A 326ILE A 350 | CTP A 500 (-4.1A)NoneCTP A 500 (-3.6A)None | 0.79A | 1t7jB-1u7wA:undetectable | 1t7jB-1u7wA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yp4 | GLUCOSE-1-PHOSPHATEADENYLYLTRANSFERASESMALL SUBUNIT (Solanumtuberosum) |
PF00483(NTP_transferase) | 4 | ALA A 143ASP A 145GLY A 255ILE A 259 | ADP A 557 (-3.5A)ADP A 557 (-3.2A)ADP A 557 (-3.6A)None | 0.83A | 1t7jB-1yp4A:undetectable | 1t7jB-1yp4A:12.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3o | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Desulfovibrioafricanus) |
PF01558(POR)PF01855(POR_N)PF02775(TPP_enzyme_C)PF10371(EKR)PF13484(Fer4_16)PF17147(PFOR_II) | 4 | ASP A 990GLY A 839ILE A 843THR A 818 | NoneTPP A2236 (-3.3A)NoneNone | 0.74A | 1t7jB-2c3oA:undetectable | 1t7jB-2c3oA:6.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2czr | TBP-INTERACTINGPROTEIN (Thermococcuskodakarensis) |
PF15517(TBPIP_N) | 4 | ALA A 47ASP A 45GLY A 8THR A 85 | None | 0.80A | 1t7jB-2czrA:undetectable | 1t7jB-2czrA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4e | 5-CARBOXYMETHYL-2-HYDROXYMUCONATESEMIALDEHYDEDEHYDROGENASE (Thermusthermophilus) |
PF00171(Aldedh) | 4 | ALA A 69ASP A 67GLY A 167ILE A 168 | None | 0.72A | 1t7jB-2d4eA:undetectable | 1t7jB-2d4eA:11.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4e | 5-CARBOXYMETHYL-2-HYDROXYMUCONATESEMIALDEHYDEDEHYDROGENASE (Thermusthermophilus) |
PF00171(Aldedh) | 4 | ALA A 491ASP A 493GLY A 476THR A 246 | None | 0.84A | 1t7jB-2d4eA:undetectable | 1t7jB-2d4eA:11.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fmb | EQUINE INFECTIOUSANEMIA VIRUSPROTEASE (Equineinfectiousanemia virus) |
PF00077(RVP) | 4 | ASP A 25ALA A 28VAL A 32GLY A 55 | LP1 A 201 (-2.3A)LP1 A 201 (-3.5A)NoneLP1 A 201 (-3.4A) | 0.32A | 1t7jB-2fmbA:15.0 | 1t7jB-2fmbA:31.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fpo | METHYLASE YHHF (Escherichiacoli) |
PF03602(Cons_hypoth95) | 4 | ASP A 58ALA A 61VAL A 105ILE A 12 | None | 0.76A | 1t7jB-2fpoA:undetectable | 1t7jB-2fpoA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3e | DIAMINOPIMELATEDECARBOXYLASE (Aquifexaeolicus) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | ALA A 355VAL A 371GLY A 345ILE A 308 | None | 0.80A | 1t7jB-2p3eA:undetectable | 1t7jB-2p3eA:13.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pz0 | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Caldanaerobactersubterraneus) |
PF03009(GDPD) | 4 | ASP A 234GLY A 42ILE A 43THR A 218 | None | 0.82A | 1t7jB-2pz0A:undetectable | 1t7jB-2pz0A:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rb7 | PEPTIDASE,M20/M25/M40 FAMILY (Desulfovibrioalaskensis) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | VAL A 269GLY A 246ILE A 231THR A 208 | None | 0.70A | 1t7jB-2rb7A:undetectable | 1t7jB-2rb7A:14.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rkf | PROTEASE RETROPEPSIN (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 25ALA A 28GLY A 49ILE A 50 | AB1 A 501 (-2.4A)AB1 A 501 (-3.5A)AB1 A 501 (-3.5A)AB1 A 501 (-3.8A) | 0.44A | 1t7jB-2rkfA:20.7 | 1t7jB-2rkfA:82.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uy3 | ENDOCHITINASE (Saccharomycescerevisiae) |
PF00704(Glyco_hydro_18) | 4 | ASP A 155ASP A 286GLY A 247ILE A 211 | H33 A1311 (-3.0A)NoneNoneNone | 0.80A | 1t7jB-2uy3A:undetectable | 1t7jB-2uy3A:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yxg | DIHYDRODIPICOLINATESYNTHASE (Methanocaldococcusjannaschii) |
PF00701(DHDPS) | 4 | ALA A 98VAL A 130GLY A 37ILE A 38 | None | 0.85A | 1t7jB-2yxgA:undetectable | 1t7jB-2yxgA:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5w | PROBABLEPEROXIREDOXIN (Aeropyrumpernix) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 4 | ALA A 103ASP A 77GLY A 73ILE A 72 | None | 0.82A | 1t7jB-3a5wA:undetectable | 1t7jB-3a5wA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9g | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrobaculumaerophilum) |
PF07995(GSDH) | 4 | ALA A 281ASP A 220VAL A 229ILE A 320 | None | 0.84A | 1t7jB-3a9gA:undetectable | 1t7jB-3a9gA:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axs | PROBABLEN(2),N(2)-DIMETHYLGUANOSINE TRNAMETHYLTRANSFERASETRM1 (Aquifexaeolicus) |
PF02005(TRM) | 4 | ALA A 162GLY A 190ILE A 193THR A 136 | SO4 A 503 (-3.5A)NoneNoneNone | 0.74A | 1t7jB-3axsA:undetectable | 1t7jB-3axsA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9n | PUTATIVE SHORT-CHAINDEHYDROGENASE/REDUCTASE (Corynebacteriumglutamicum) |
PF00106(adh_short) | 5 | ASP A 213VAL A 211GLY A 124ILE A 167THR A 221 | None | 1.29A | 1t7jB-3e9nA:undetectable | 1t7jB-3e9nA:16.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebv | CHINITASE A (Streptomycescoelicolor) |
PF00704(Glyco_hydro_18) | 4 | ALA A 6VAL A 175GLY A 9ILE A 33 | None | 0.79A | 1t7jB-3ebvA:undetectable | 1t7jB-3ebvA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3edn | PHENAZINEBIOSYNTHESISPROTEIN, PHZF FAMILY (Bacillusanthracis) |
PF02567(PhzC-PhzF) | 4 | ALA A 125GLY A 234ILE A 285THR A 273 | None | 0.79A | 1t7jB-3ednA:undetectable | 1t7jB-3ednA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3io0 | ETUB PROTEIN (Clostridiumkluyveri) |
PF00936(BMC) | 4 | ALA A 202GLY A 221ILE A 222THR A 303 | None | 0.85A | 1t7jB-3io0A:undetectable | 1t7jB-3io0A:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju8 | SUCCINYLGLUTAMICSEMIALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 4 | VAL A 309GLY A 363ILE A 364THR A 306 | NoneNoneNoneGOL A 510 (-4.4A) | 0.79A | 1t7jB-3ju8A:undetectable | 1t7jB-3ju8A:11.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 4 | ALA A 219ASP A 264VAL A 314ILE A 90 | None | 0.71A | 1t7jB-3lk6A:undetectable | 1t7jB-3lk6A:10.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lmz | PUTATIVE SUGARISOMERASE (Parabacteroidesdistasonis) |
PF01261(AP_endonuc_2) | 4 | ASP A 221VAL A 219GLY A 161ILE A 164 | None | 0.78A | 1t7jB-3lmzA:undetectable | 1t7jB-3lmzA:17.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mws | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 6 | ASP A 25ALA A 28ASP A 30VAL A 32GLY A 49ILE A 50 | None | 0.29A | 1t7jB-3mwsA:19.6 | 1t7jB-3mwsA:74.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ppi | 3-HYDROXYACYL-COADEHYDROGENASE TYPE-2 (Mycobacteriumavium) |
PF13561(adh_short_C2) | 4 | ALA A 85VAL A 125GLY A 16ILE A 37 | None | 0.73A | 1t7jB-3ppiA:undetectable | 1t7jB-3ppiA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s46 | ALANINE RACEMASE (Streptococcuspneumoniae) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | ALA A 216ASP A 60GLY A 161ILE A 162 | None | 0.82A | 1t7jB-3s46A:undetectable | 1t7jB-3s46A:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3slz | GAG-PRO-POLPOLYPROTEIN (Murine leukemiavirus) |
PF00077(RVP) | 4 | ASP A 32ALA A 35VAL A 39GLY A 56 | 3TL A 126 (-2.4A)3TL A 126 ( 4.0A)None3TL A 126 (-3.4A) | 0.54A | 1t7jB-3slzA:11.2 | 1t7jB-3slzA:26.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swt | TAURINE CATABOLISMDIOXYGENASE, TAUD (Mycobacteriummarinum) |
PF02668(TauD) | 4 | ASP A 280VAL A 190GLY A 197THR A 130 | None | 0.82A | 1t7jB-3swtA:undetectable | 1t7jB-3swtA:16.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3t3c | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 25ALA A 28ASP A 30VAL A 32 | 017 A 201 (-2.6A)017 A 201 (-3.5A)017 A 201 (-4.2A)None | 0.62A | 1t7jB-3t3cA:18.4 | 1t7jB-3t3cA:77.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3t3c | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 25ALA A 28GLY A 49ILE A 50 | 017 A 201 (-2.6A)017 A 201 (-3.5A)017 A 201 (-4.0A)017 A 201 (-3.3A) | 0.57A | 1t7jB-3t3cA:18.4 | 1t7jB-3t3cA:77.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3t3c | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 25ALA A 28VAL A 32ILE A 50 | 017 A 201 (-2.6A)017 A 201 (-3.5A)None017 A 201 (-3.3A) | 0.55A | 1t7jB-3t3cA:18.4 | 1t7jB-3t3cA:77.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tcr | MOLYBDOPTERINBIOSYNTHESIS PROTEIN (Mycobacteroidesabscessus) |
PF00994(MoCF_biosynth) | 4 | ALA A 77GLY A 141ILE A 139THR A 103 | None | 0.84A | 1t7jB-3tcrA:undetectable | 1t7jB-3tcrA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tpk | IMMUNOGLOBULIN HEAVYCHAIN ANTIBODYVARIABLE DOMAIN KW1 (Camelidae) |
PF07686(V-set) | 4 | ASP A 62VAL A 64GLY A 50ILE A 51 | None | 0.80A | 1t7jB-3tpkA:undetectable | 1t7jB-3tpkA:20.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ttp | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 25ALA A 28ASP A 30GLY A 49ILE A 50 | 017 A 201 (-2.6A)017 A 201 (-3.4A)017 A 201 (-4.6A)017 A 201 (-3.0A)017 A 201 (-3.3A) | 0.58A | 1t7jB-3ttpA:19.2 | 1t7jB-3ttpA:77.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3u7s | POL POLYPROTEIN (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 25ALA A 28GLY A 49ILE A 50 | 017 A 202 ( 2.5A)017 A 201 (-3.4A)017 A 202 (-2.9A)017 A 201 ( 3.5A) | 0.45A | 1t7jB-3u7sA:19.6 | 1t7jB-3u7sA:80.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vrb | FLAVOPROTEIN SUBUNITOF COMPLEX IIIRON-SULFUR SUBUNITOF SUCCINATEDEHYDROGENASE (Ascaris suum) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF13085(Fer2_3)PF13534(Fer4_17) | 4 | VAL A 283GLY B 92ILE B 93THR A 247 | NoneFES B 301 ( 3.8A)NoneFAD A 702 (-4.6A) | 0.82A | 1t7jB-3vrbA:undetectable | 1t7jB-3vrbA:8.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wgh | REDOX-SENSINGTRANSCRIPTIONALREPRESSOR REX (Thermoanaerobacterethanolicus) |
PF02629(CoA_binding)PF06971(Put_DNA-bind_N) | 4 | ALA A 163VAL A 184GLY A 150ILE A 151 | None | 0.84A | 1t7jB-3wghA:undetectable | 1t7jB-3wghA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zxl | HIAXHD3 (Humicolainsolens) |
PF04616(Glyco_hydro_43) | 4 | ALA A 218ASP A 167GLY A 275ILE A 276 | NoneB3P A1560 (-2.9A)NoneNone | 0.76A | 1t7jB-3zxlA:undetectable | 1t7jB-3zxlA:10.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cql | ESTRADIOL17-BETA-DEHYDROGENASE 8 (Homo sapiens) |
PF13561(adh_short_C2) | 5 | ASP A 229ASP A 235VAL A 233GLY A 257ILE A 222 | None | 1.02A | 1t7jB-4cqlA:undetectable | 1t7jB-4cqlA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cvy | DIOXYGENASERV3406/MT3514 (Mycobacteriumtuberculosis) |
PF02668(TauD) | 4 | ASP A 276VAL A 186GLY A 193THR A 129 | None | 0.81A | 1t7jB-4cvyA:undetectable | 1t7jB-4cvyA:15.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gft | NANOBODY (Lama glama) |
PF07686(V-set) | 4 | ASP B 64VAL B 66GLY B 52ILE B 53 | None | 0.80A | 1t7jB-4gftB:undetectable | 1t7jB-4gftB:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4inf | METAL-DEPENDENTHYDROLASE (Novosphingobiumaromaticivorans) |
PF04909(Amidohydro_2) | 4 | ASP A 314VAL A 291GLY A 213THR A 287 | CA A 401 (-2.6A)NoneNoneNone | 0.57A | 1t7jB-4infA:undetectable | 1t7jB-4infA:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0q | ELONGATION FACTORTU-A (Pseudomonasputida) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | ASP A 87GLY A 16ILE A 103THR A 116 | None | 0.84A | 1t7jB-4j0qA:undetectable | 1t7jB-4j0qA:12.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j5i | ALPHA-KETOGLUTARATE-DEPENDENT TAURINEDIOXYGENASE (Mycolicibacteriumsmegmatis) |
PF02668(TauD) | 4 | ASP A 273VAL A 183GLY A 190THR A 127 | None | 0.84A | 1t7jB-4j5iA:undetectable | 1t7jB-4j5iA:16.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kwg | ALDEHYDEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF00171(Aldedh) | 4 | ALA A 194GLY A 229ILE A 232THR A 244 | None | 0.74A | 1t7jB-4kwgA:undetectable | 1t7jB-4kwgA:11.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ng3 | 5-CARBOXYVANILLATEDECARBOXYLASE (Sphingomonaspaucimobilis) |
PF04909(Amidohydro_2) | 4 | ASP A 296VAL A 273GLY A 198THR A 269 | MN A 401 ( 2.5A)NoneNoneNone | 0.54A | 1t7jB-4ng3A:undetectable | 1t7jB-4ng3A:14.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4njv | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 7 | ASP A 25ALA A 28ASP A 30VAL A 32GLY A 49ILE A 50THR A 82 | RIT A 500 (-2.4A)RIT A 500 (-3.6A)RIT A 500 (-4.8A)NoneRIT A 500 (-3.4A)RIT A 500 (-4.3A)RIT A 500 (-3.5A) | 0.43A | 1t7jB-4njvA:20.5 | 1t7jB-4njvA:86.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nn3 | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | ALA A 95ASP A 175VAL A 173ILE A 109 | NonePGE A 402 (-3.0A)NoneNone | 0.79A | 1t7jB-4nn3A:undetectable | 1t7jB-4nn3A:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ntc | GLIT (Aspergillusfumigatus) |
PF07992(Pyr_redox_2) | 4 | ASP A 43ALA A 21GLY A 123THR A 90 | FAD A 401 (-3.2A)FAD A 401 (-4.1A)FAD A 401 (-3.5A)FAD A 401 (-4.2A) | 0.84A | 1t7jB-4ntcA:undetectable | 1t7jB-4ntcA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pq1 | PUTATIVE ELECTRONTRANSPORT RELATEDPROTEIN (Corynebacteriumdiphtheriae) |
PF00578(AhpC-TSA) | 4 | ASP A 93VAL A 97ILE A 157THR A 106 | None | 0.69A | 1t7jB-4pq1A:undetectable | 1t7jB-4pq1A:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2c | CRISPR-ASSOCIATEDHELICASE CAS3 (Thermobaculumterrenum) |
PF00271(Helicase_C) | 4 | ASP A 196GLY A 101ILE A 141THR A 148 | None | 0.85A | 1t7jB-4q2cA:undetectable | 1t7jB-4q2cA:8.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3w | 2-AMINOMUCONATE6-SEMIALDEHYDEDEHYDROGENASE (Burkholderiacenocepacia) |
PF00171(Aldedh) | 4 | ALA A 55ASP A 53GLY A 158ILE A 159 | None | 0.63A | 1t7jB-4u3wA:undetectable | 1t7jB-4u3wA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uoz | BETA-GALACTOSIDASE (Bifidobacteriumanimalis) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | ASP A 562ASP A 565GLY A 525ILE A 524 | None | 0.81A | 1t7jB-4uozA:undetectable | 1t7jB-4uozA:9.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0e | PUTATIVE DIOXYGENASE (Mycobacteroidesabscessus) |
PF02668(TauD) | 4 | ASP A 287VAL A 197GLY A 204THR A 136 | None | 0.83A | 1t7jB-4y0eA:undetectable | 1t7jB-4y0eA:15.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ydf | HTLV-1 PROTEASE (PrimateT-lymphotropicvirus 1) |
PF00077(RVP) | 4 | ASP A 32ALA A 35VAL A 39GLY A 58 | 4B1 A 201 (-2.9A)4B1 A 201 (-3.6A)None4B1 A 201 (-3.4A) | 0.46A | 1t7jB-4ydfA:13.4 | 1t7jB-4ydfA:30.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zv4 | ELONGATION FACTOR TU (Pseudomonasaeruginosa) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | ASP A 87GLY A 16ILE A 103THR A 116 | None | 0.75A | 1t7jB-4zv4A:undetectable | 1t7jB-4zv4A:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 4 | ALA A 405ASP A 401GLY A 426ILE A 425 | None CL A 615 ( 3.8A)NoneNone | 0.83A | 1t7jB-5dqfA:undetectable | 1t7jB-5dqfA:11.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e26 | PANTOTHENATE KINASE2, MITOCHONDRIAL (Homo sapiens) |
PF03630(Fumble) | 4 | ALA A 535ASP A 539GLY A 502ILE A 501 | None | 0.84A | 1t7jB-5e26A:undetectable | 1t7jB-5e26A:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fly | FERRICHROME-BINDINGPERIPLASMIC PROTEIN (Staphylococcuspseudintermedius) |
PF01497(Peripla_BP_2) | 4 | ALA A 243ASP A 217GLY A 212THR A 221 | None | 0.63A | 1t7jB-5flyA:undetectable | 1t7jB-5flyA:14.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gtk | BETAINE-ALDEHYDEDEHYDROGENASE (Bacillus cereus) |
PF00171(Aldedh) | 4 | ALA A 193GLY A 228ILE A 231THR A 243 | NAD A 501 (-4.0A)NAD A 501 (-3.5A)NoneNAD A 501 (-4.7A) | 0.80A | 1t7jB-5gtkA:undetectable | 1t7jB-5gtkA:11.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ho9 | EXTRACELLULARARABINANASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43)PF16369(GH43_C) | 4 | ALA A 354ASP A 348GLY A 344THR A 306 | None | 0.80A | 1t7jB-5ho9A:undetectable | 1t7jB-5ho9A:10.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huq | LACTATE RACEMIZATIONOPERON PROTEIN LARA (Lactobacillusplantarum) |
PF09861(DUF2088) | 4 | ALA A 360ASP A 356GLY A 202ILE A 346 | None | 0.81A | 1t7jB-5huqA:undetectable | 1t7jB-5huqA:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iry | DESMOCOLLIN-1 (Homo sapiens) |
PF00028(Cadherin) | 4 | ASP A 363GLY A 391ILE A 386THR A 426 | CA A 613 ( 4.5A)NoneNoneMAN A 618 (-2.0A) | 0.80A | 1t7jB-5iryA:undetectable | 1t7jB-5iryA:11.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8c | 3-DEOXY-ALPHA-D-MANNO-OCTULOSONATE8-OXIDASE (Shewanellaoneidensis) |
PF00465(Fe-ADH) | 4 | ASP A 104GLY A 246ILE A 249THR A 168 | NAD A 401 (-2.8A)NoneNoneNone | 0.77A | 1t7jB-5k8cA:undetectable | 1t7jB-5k8cA:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t13 | CYANURIC ACIDAMIDOHYDROLASE (Enterobactercloacae) |
PF09663(Amido_AtzD_TrzD) | 4 | ASP A 216VAL A 218GLY A 201ILE A 202 | None | 0.82A | 1t7jB-5t13A:undetectable | 1t7jB-5t13A:15.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5t2z | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 25ALA A 28ASP A 30VAL A 32 | None | 0.47A | 1t7jB-5t2zA:19.6 | 1t7jB-5t2zA:78.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5t2z | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 25ALA A 28VAL A 32GLY A 49ILE A 50 | None | 0.27A | 1t7jB-5t2zA:19.6 | 1t7jB-5t2zA:78.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vm0 | CAMELID NANOBODY VHHT9 (Lama glama) |
no annotation | 4 | ASP A 64VAL A 66GLY A 52ILE A 53 | None | 0.82A | 1t7jB-5vm0A:undetectable | 1t7jB-5vm0A:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5voh | NADH OXIDASE (Lactobacillusbrevis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | ASP A 234ALA A 147GLY A 170THR A 151 | None | 0.80A | 1t7jB-5vohA:undetectable | 1t7jB-5vohA:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w0s | 60 KDA CHAPERONIN (Escherichiacoli) |
PF00118(Cpn60_TCP1) | 4 | ASP A 495VAL A 411GLY A 148ILE A 162 | None | 0.71A | 1t7jB-5w0sA:undetectable | 1t7jB-5w0sA:10.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w75 | ELONGATION FACTOR TU (Thermotoganeapolitana) |
no annotation | 4 | ASP A 87GLY A 16ILE A 103THR A 116 | None | 0.73A | 1t7jB-5w75A:undetectable | 1t7jB-5w75A:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w76 | ANCESTRAL ELOGATIONFACTOR N153 (syntheticconstruct) |
no annotation | 4 | ASP A 87GLY A 16ILE A 103THR A 116 | None | 0.68A | 1t7jB-5w76A:undetectable | 1t7jB-5w76A:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7q | CONSENSUS ELONGATIONFACTOR (syntheticconstruct) |
no annotation | 4 | ASP A 87GLY A 16ILE A 103THR A 116 | None | 0.67A | 1t7jB-5w7qA:undetectable | 1t7jB-5w7qA:25.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwq | FUNGAL CHITINASEFROM RHIZOMUCORMIEHEI (NATIVEPROTEIN) (Rhizomucormiehei) |
no annotation | 4 | ASP A 180VAL A 101GLY A 306ILE A 253 | None | 0.82A | 1t7jB-5xwqA:undetectable | 1t7jB-5xwqA:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zb3 | - (-) |
no annotation | 4 | ALA A 378GLY A 385ILE A 392THR A 402 | None | 0.83A | 1t7jB-5zb3A:undetectable | 1t7jB-5zb3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zbk | PUTATIVE CYTOKININRIBOSIDE5'-MONOPHOSPHATEPHOSPHORIBOHYDROLASE (Pseudomonasaeruginosa) |
no annotation | 4 | ASP A 53GLY A 41ILE A 65THR A 37 | None | 0.72A | 1t7jB-5zbkA:undetectable | 1t7jB-5zbkA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cip | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Moorellathermoacetica) |
no annotation | 4 | ASP A 994GLY A 836ILE A 840THR A 815 | NoneHTL A1204 (-3.4A)NoneNone | 0.79A | 1t7jB-6cipA:undetectable | 1t7jB-6cipA:25.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fe4 | NB113 (Vicugna pacos) |
no annotation | 4 | ASP F 62VAL F 64GLY F 50ILE F 51 | None | 0.84A | 1t7jB-6fe4F:undetectable | 1t7jB-6fe4F:22.00 |