SIMILAR PATTERNS OF AMINO ACIDS FOR 1SV9_A_DIFA701_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1a2a PHOSPHOLIPASE A2

(Gloydius halys) 		PF00068
(Phospholip_A2_1) 		8 LEU A   2
ALA A  18
ILE A  19
CYH A  29
GLY A  30
CYH A  45
HIS A  48
PHE A 106
 None
 0.54A 1sv9A-1a2aA:
22.6		 1sv9A-1a2aA:
62.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ae7 PHOSPHOLIPASE A2

(Notechis
scutatus) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
GLY A  30
HIS A  48
PHE A 106
 None
 0.81A 1sv9A-1ae7A:
16.2		 1sv9A-1ae7A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1aok VIPOXIN COMPLEX

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		4 LEU B   2
GLY B  30
HIS B  48
PHE B 106
 None
ACT  B 134 (-3.7A)
ACT  B 134 (-3.6A)
ACT  B 134 (-4.8A)
 0.63A 1sv9A-1aokB:
20.8		 1sv9A-1aokB:
56.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bpq PHOSPHOLIPASE A2

(Bos taurus) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
GLY A  30
HIS A  48
PHE A 106
 None
CA  A 124 (-4.2A)
None
None
 0.65A 1sv9A-1bpqA:
18.0		 1sv9A-1bpqA:
39.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ctm CYTOCHROME F

(Brassica rapa) 		PF01333
(Apocytochr_F_C)
PF16639
(Apocytochr_F_N) 		4 ILE A 115
GLY A 152
CYH A  21
HIS A  25
 None
None
HEM  A 253 (-1.8A)
HEM  A 253 (-3.1A)
 0.83A 1sv9A-1ctmA:
undetectable		 1sv9A-1ctmA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fok PROTEIN (FOKI
RESTRICTION
ENDONUCLEASE)

(Planomicrobium
okeanokoites) 		PF02980
(FokI_C)
PF02981
(FokI_N)
PF09254
(Endonuc-FokI_C)
PF16902
(Type2_restr_D3) 		4 LEU A 168
ALA A 227
ILE A 230
GLY A 185
 None
 0.84A 1sv9A-1fokA:
undetectable		 1sv9A-1fokA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fw8 PHOSPHOGLYCERATE
KINASE

(Saccharomyces
cerevisiae) 		PF00162
(PGK) 		4 LEU A 149
ALA A 136
ILE A 160
GLY A 139
 None
 0.81A 1sv9A-1fw8A:
undetectable		 1sv9A-1fw8A:
16.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1g0z PHOSPHOLIPASE A2

(Bungarus
caeruleus) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
GLY A  30
HIS A  48
PHE A 101
 None
 0.74A 1sv9A-1g0zA:
17.2		 1sv9A-1g0zA:
39.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gff BACTERIOPHAGE G4
CAPSID PROTEINS GPF,
GPG, GPJ

(Escherichia
virus G4) 		PF02306
(Phage_G) 		5 LEU 2  73
ALA 2  90
ILE 2  91
HIS 2   9
PHE 2 124
 None
 1.39A 1sv9A-1gff2:
undetectable		 1sv9A-1gff2:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hfe PROTEIN (FE-ONLY
HYDROGENASE
(E.C.1.18.99.1)
(LARGER SUBUNIT))

(Desulfovibrio
vulgaris) 		PF02906
(Fe_hyd_lg_C)
PF13237
(Fer4_10) 		4 ALA L 236
ILE L 235
CYH L 382
GLY L 385
 SF4  L 424 ( 4.0A)
None
SF4  L 424 (-2.3A)
SF4  L 424 ( 3.5A)
 0.85A 1sv9A-1hfeL:
undetectable		 1sv9A-1hfeL:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lml LEISHMANOLYSIN

(Leishmania
major) 		PF01457
(Peptidase_M8) 		4 LEU A 118
ALA A 247
ILE A 250
HIS A 135
 None
 0.66A 1sv9A-1lmlA:
undetectable		 1sv9A-1lmlA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m6e S-ADENOSYL-L-METHION
INE:SALICYLIC ACID
CARBOXYL
METHYLTRANSFERASE

(Clarkia breweri) 		PF03492
(Methyltransf_7) 		5 LEU X 134
ALA X  56
ILE X 143
CYH X  60
GLY X  59
 None
None
None
None
SAH  X2814 (-3.7A)
 1.07A 1sv9A-1m6eX:
undetectable		 1sv9A-1m6eX:
14.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m8r PHOSPHOLIPASE A2

(Gloydius halys) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
GLY A  30
HIS A  48
PHE A 106
 None
BU1  A1002 (-4.3A)
None
None
 0.79A 1sv9A-1m8rA:
20.9		 1sv9A-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m8t PHOSPHOLIPASE A2

(Ophiophagus
hannah) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
GLY A  30
HIS A  48
PHE A 106
 HEZ  A1002 (-4.0A)
CA  A1001 (-4.3A)
None
None
 0.69A 1sv9A-1m8tA:
18.1		 1sv9A-1m8tA:
40.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nfg D-HYDANTOINASE

(Ralstonia
pickettii) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 ALA A 366
ILE A  54
GLY A  84
PHE A 361
 None
 0.83A 1sv9A-1nfgA:
undetectable		 1sv9A-1nfgA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nub BASEMENT MEMBRANE
PROTEIN BM-40

(Homo sapiens) 		PF00050
(Kazal_1)
PF09289
(FOLN)
PF10591
(SPARC_Ca_bdg) 		4 LEU A 258
ALA A 265
ILE A 264
GLY A 271
 None
 0.66A 1sv9A-1nubA:
undetectable		 1sv9A-1nubA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oa3 ENDO-BETA-1-4-GLUCAN
ASE

(Trichoderma
citrinoviride) 		PF01670
(Glyco_hydro_12) 		4 LEU A 208
ALA A  94
ILE A  92
GLY A 122
 None
None
None
NAG  A1220 ( 4.1A)
 0.79A 1sv9A-1oa3A:
undetectable		 1sv9A-1oa3A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1owx LUPUS LA PROTEIN

(Homo sapiens) 		PF08777
(RRM_3) 		4 LEU A 234
ALA A 314
ILE A 318
GLY A 271
 None
 0.84A 1sv9A-1owxA:
undetectable		 1sv9A-1owxA:
22.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1p7o PHOSPHOLIPASE A2

(Micropechis
ikaheca) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
GLY A  30
HIS A  48
PHE A 106
 None
 0.63A 1sv9A-1p7oA:
18.2		 1sv9A-1p7oA:
38.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pem RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
ALPHA CHAIN

(Salmonella
enterica) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF08343
(RNR_N) 		4 LEU A 354
ALA A 261
ILE A 266
GLY A 289
 None
 0.80A 1sv9A-1pemA:
undetectable		 1sv9A-1pemA:
9.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1po8 PHOSPHOLIPASE A2

(Bungarus
caeruleus) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
GLY A  30
HIS A  48
PHE A 101
 None
SHV  A 122 ( 3.7A)
SHV  A 122 (-4.1A)
None
 0.62A 1sv9A-1po8A:
17.4		 1sv9A-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pwo PHOSPHOLIPASE A2

(Micropechis
ikaheca) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
GLY A  30
HIS A  48
PHE A 106
 None
 0.82A 1sv9A-1pwoA:
17.6		 1sv9A-1pwoA:
36.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1q6v PHOSPHOLIPASE A2
VRV-PL-VIIIA

(Daboia russelii) 		PF00068
(Phospholip_A2_1) 		6 LEU A   2
ALA A  18
ILE A  19
GLY A  30
HIS A  48
PHE A 106
 None
 0.71A 1sv9A-1q6vA:
25.2		 1sv9A-1q6vA:
95.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qdm PROPHYTEPSIN

(Hordeum vulgare) 		PF00026
(Asp)
PF03489
(SapB_2)
PF05184
(SapB_1) 		4 ALA A 222
ILE A 221
GLY A 129
PHE A 158
 None
 0.84A 1sv9A-1qdmA:
undetectable		 1sv9A-1qdmA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN

(Rhinovirus B) 		PF00073
(Rhv) 		5 LEU 2 181
ALA 2 169
ILE 2 170
GLY 2 175
HIS 2 130
 None
 1.36A 1sv9A-1rhi2:
undetectable		 1sv9A-1rhi2:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rjw ALCOHOL
DEHYDROGENASE

(Geobacillus
stearothermophilus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		5 LEU A 336
ALA A   4
ILE A  58
GLY A  60
PHE A 320
 None
 1.35A 1sv9A-1rjwA:
undetectable		 1sv9A-1rjwA:
16.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s8h PHOSPHOLIPASE A2
HOMOLOG

(Agkistrodon
contortrix) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
ALA A  18
ILE A  19
HIS A  48
 None
 0.39A 1sv9A-1s8hA:
21.0		 1sv9A-1s8hA:
64.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sra SPARC

(Homo sapiens) 		PF10591
(SPARC_Ca_bdg) 		4 LEU A 258
ALA A 265
ILE A 264
GLY A 271
 None
 0.68A 1sv9A-1sraA:
undetectable		 1sv9A-1sraA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tkl COPROPORPHYRINOGEN
III OXIDASE

(Saccharomyces
cerevisiae) 		PF01218
(Coprogen_oxidas) 		4 LEU A 178
ALA A 234
GLY A 154
PHE A 170
 None
 0.79A 1sv9A-1tklA:
undetectable		 1sv9A-1tklA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqy ACTINORHODIN
POLYKETIDE PUTATIVE
BETA-KETOACYL
SYNTHASE 2

(Streptomyces
coelicolor) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 LEU B 371
ALA B 309
ILE B 312
GLY B 298
 None
 0.65A 1sv9A-1tqyB:
undetectable		 1sv9A-1tqyB:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uc4 DIOL DEHYDRASE BETA
SUBUNIT

(Klebsiella
oxytoca) 		PF02288
(Dehydratase_MU) 		4 LEU B 203
ALA B 157
GLY B  81
HIS B  84
 None
CNC  B2601 (-3.2A)
None
None
 0.71A 1sv9A-1uc4B:
undetectable		 1sv9A-1uc4B:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1urj MAJOR DNA-BINDING
PROTEIN

(Human
alphaherpesvirus
1) 		PF00747
(Viral_DNA_bp) 		4 LEU A 981
ALA A 532
ILE A 533
GLY A1001
 None
 0.83A 1sv9A-1urjA:
undetectable		 1sv9A-1urjA:
8.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vap PHOSPHOLIPASE A2

(Agkistrodon
piscivorus) 		PF00068
(Phospholip_A2_1) 		4 LEU A   2
GLY A  29
HIS A  47
PHE A  96
 None
 0.51A 1sv9A-1vapA:
21.6		 1sv9A-1vapA:
60.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vb5 TRANSLATION
INITIATION FACTOR
EIF-2B

(Pyrococcus
horikoshii) 		PF01008
(IF-2B) 		4 LEU A  51
ALA A  69
ILE A  72
GLY A  28
 None
 0.83A 1sv9A-1vb5A:
undetectable		 1sv9A-1vb5A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w0h 3'-5' EXONUCLEASE
ERI1

(Homo sapiens) 		PF00929
(RNase_T) 		4 ALA A 137
ILE A 151
GLY A 295
HIS A 293
 AMP  A1002 (-3.6A)
None
MG  A1001 ( 4.3A)
AMP  A1002 (-3.9A)
 0.83A 1sv9A-1w0hA:
undetectable		 1sv9A-1w0hA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xpo RHO TRANSCRIPTION
TERMINATION FACTOR

(Escherichia
coli) 		PF00006
(ATP-synt_ab)
PF07497
(Rho_RNA_bind)
PF07498
(Rho_N) 		4 LEU A  26
ALA A  37
ILE A  38
GLY A  22
 None
 0.80A 1sv9A-1xpoA:
undetectable		 1sv9A-1xpoA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xtp LMAJ004091AAA

(Leishmania
major) 		PF05891
(Methyltransf_PK) 		5 ALA A 168
ILE A 169
CYH A 100
GLY A 101
PHE A 179
 None
None
None
SAI  A 401 (-3.4A)
None
 1.43A 1sv9A-1xtpA:
undetectable		 1sv9A-1xtpA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y6j L-LACTATE
DEHYDROGENASE

(Ruminiclostridium
thermocellum) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 LEU A  35
ALA A  49
ILE A  52
GLY A  19
 None
 0.82A 1sv9A-1y6jA:
undetectable		 1sv9A-1y6jA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8t HYPOTHETICAL PROTEIN
RV0983

(Mycobacterium
tuberculosis) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 LEU A 180
ALA A 207
ILE A 208
GLY A 170
 None
 0.82A 1sv9A-1y8tA:
undetectable		 1sv9A-1y8tA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zch HYPOTHETICAL
OXIDOREDUCTASE YCND

(Bacillus
subtilis) 		PF00881
(Nitroreductase) 		5 LEU A 161
ALA A 125
ILE A  30
GLY A 119
HIS A  11
 None
None
None
None
FMN  A 301 (-4.1A)
 1.32A 1sv9A-1zchA:
undetectable		 1sv9A-1zchA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zej 3-HYDROXYACYL-COA
DEHYDROGENASE

(Archaeoglobus
fulgidus) 		PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 LEU A  27
ALA A  20
ILE A  19
GLY A  14
 None
 0.79A 1sv9A-1zejA:
undetectable		 1sv9A-1zejA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1a INTERFERON-INDUCED,
DOUBLE-STRANDED
RNA-ACTIVATED
PROTEIN KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU B 474
ILE B 420
GLY B 401
HIS B 406
 None
 0.78A 1sv9A-2a1aB:
undetectable		 1sv9A-2a1aB:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a7n L(+)-MANDELATE
DEHYDROGENASE

(Pseudomonas
putida;
Spinacia
oleracea) 		PF01070
(FMN_dh) 		4 LEU A 130
ALA A 145
ILE A 115
GLY A 140
 None
 0.81A 1sv9A-2a7nA:
undetectable		 1sv9A-2a7nA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bb6 TRANSCOBALAMIN II

(Bos taurus) 		PF01122
(Cobalamin_bind) 		4 LEU A 161
ALA A 207
ILE A 204
GLY A 185
 None
 0.81A 1sv9A-2bb6A:
undetectable		 1sv9A-2bb6A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2be4 HYPOTHETICAL PROTEIN
LOC449832

(Danio rerio) 		PF13202
(EF-hand_5)
PF13499
(EF-hand_7) 		4 ALA A 203
GLY A 211
HIS A 270
PHE A 198
 None
 0.78A 1sv9A-2be4A:
undetectable		 1sv9A-2be4A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bng MB2760

(Mycobacterium
tuberculosis) 		PF07858
(LEH) 		4 LEU A  25
ILE A  80
CYH A 107
GLY A 108
 None
 0.70A 1sv9A-2bngA:
undetectable		 1sv9A-2bngA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2buj SERINE/THREONINE-PRO
TEIN KINASE 16

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 221
ILE A 154
GLY A 135
HIS A 140
 None
 0.74A 1sv9A-2bujA:
undetectable		 1sv9A-2bujA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2clb DPS-LIKE PROTEIN

(Sulfolobus
solfataricus) 		PF00210
(Ferritin) 		4 LEU A 117
ALA A  63
ILE A  62
GLY A  56
 None
 0.81A 1sv9A-2clbA:
undetectable		 1sv9A-2clbA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dqi LYSOZYME BINDING IG
KAPPA CHAIN V23-J2
REGION

(Mus musculus) 		PF07686
(V-set) 		4 LEU L  33
ALA L  25
ILE L   2
GLY L  99
 None
 0.83A 1sv9A-2dqiL:
undetectable		 1sv9A-2dqiL:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g02 NISIN BIOSYNTHESIS
PROTEIN NISC

(Lactococcus
lactis) 		PF05147
(LANC_like) 		4 LEU A 405
CYH A 385
GLY A 384
PHE A 359
 None
 0.74A 1sv9A-2g02A:
undetectable		 1sv9A-2g02A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ghi TRANSPORT PROTEIN

(Plasmodium
yoelii) 		PF00005
(ABC_tran) 		4 ALA A 165
ILE A 164
GLY A 159
PHE A 179
 None
 0.75A 1sv9A-2ghiA:
undetectable		 1sv9A-2ghiA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h6e D-ARABINOSE
1-DEHYDROGENASE

(Sulfolobus
solfataricus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 255
ALA A 226
ILE A 230
GLY A 201
 None
 0.83A 1sv9A-2h6eA:
undetectable		 1sv9A-2h6eA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hrz NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE

(Agrobacterium
fabrum) 		PF01370
(Epimerase) 		4 ALA A  89
ILE A  90
CYH A 166
PHE A 132
 None
 0.81A 1sv9A-2hrzA:
undetectable		 1sv9A-2hrzA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ia7 TAIL LYSOZYME,
PUTATIVE

(Geobacter
sulfurreducens) 		PF04965
(GPW_gp25) 		4 ILE A  39
CYH A  56
GLY A  55
PHE A 127
 None
 0.80A 1sv9A-2ia7A:
undetectable		 1sv9A-2ia7A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2if2 DEPHOSPHO-COA KINASE

(Aquifex
aeolicus) 		PF01121
(CoaE) 		4 ILE A 172
CYH A  12
GLY A  13
CYH A 137
 None
SO4  A 301 (-4.9A)
SO4  A 301 (-3.5A)
None
 0.80A 1sv9A-2if2A:
undetectable		 1sv9A-2if2A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iue INTEGRIN BETA-2-LIKE
PROTEIN

(Mus musculus) 		PF00362
(Integrin_beta) 		4 LEU A  26
ALA A 202
ILE A 205
GLY A 192
 None
 0.80A 1sv9A-2iueA:
undetectable		 1sv9A-2iueA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix8 ELONGATION FACTOR 3A

(Saccharomyces
cerevisiae) 		PF00005
(ABC_tran) 		4 LEU A1313
ALA A1266
ILE A1269
GLY A1292
 None
 0.83A 1sv9A-2ix8A:
undetectable		 1sv9A-2ix8A:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ms7 MITOCHONDRIAL
ANTIVIRAL-SIGNALING
PROTEIN

(Homo sapiens) 		PF16739
(CARD_2) 		4 ALA A  85
ILE A  73
CYH A  79
GLY A  78
 None
 0.73A 1sv9A-2ms7A:
undetectable		 1sv9A-2ms7A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o0m TRANSCRIPTIONAL
REGULATOR, SORC
FAMILY

(Enterococcus
faecalis) 		PF04198
(Sugar-bind) 		4 LEU A 329
ALA A 336
ILE A 339
GLY A 308
 None
 0.82A 1sv9A-2o0mA:
undetectable		 1sv9A-2o0mA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2om5 CONTACTIN 2

(Homo sapiens) 		PF07679
(I-set)
PF13927
(Ig_3) 		4 LEU A 300
ALA A 367
ILE A 374
GLY A 322
 None
 0.85A 1sv9A-2om5A:
undetectable		 1sv9A-2om5A:
14.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2osn PHOSPHOLIPASE A2
ISOFORM 3

(Bungarus
caeruleus) 		PF00068
(Phospholip_A2_1) 		4 LEU A   4
GLY A  30
HIS A  48
PHE A 101
 None
 0.73A 1sv9A-2osnA:
17.2		 1sv9A-2osnA:
36.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pia PHTHALATE
DIOXYGENASE
REDUCTASE

(Burkholderia
cepacia) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 LEU A 143
ILE A 170
GLY A 119
PHE A 183
 None
 0.84A 1sv9A-2piaA:
undetectable		 1sv9A-2piaA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3l UNCHARACTERIZED
PROTEIN

(Shewanella
loihica) 		PF11964
(SpoIIAA-like) 		5 LEU A  41
ALA A  55
ILE A  53
GLY A  81
PHE A 111
 MPD  A 130 (-4.8A)
None
None
MPD  A 130 ( 3.9A)
MPD  A 130 (-4.8A)
 1.29A 1sv9A-2q3lA:
undetectable		 1sv9A-2q3lA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qyg RIBULOSE
BISPHOSPHATE
CARBOXYLASE-LIKE
PROTEIN 2

(Rhodopseudomonas
palustris) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		5 LEU A 270
ALA A 286
ILE A 263
GLY A 315
CYH A 352
 None
 1.39A 1sv9A-2qygA:
undetectable		 1sv9A-2qygA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2raf PUTATIVE
DINUCLEOTIDE-BINDING
OXIDOREDUCTASE

(Lactobacillus
plantarum) 		PF03807
(F420_oxidored) 		4 LEU A 150
ALA A  22
ILE A  21
GLY A  16
 None
 0.84A 1sv9A-2rafA:
undetectable		 1sv9A-2rafA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2taa TAKA-AMYLASE A

(Aspergillus
oryzae) 		PF00128
(Alpha-amylase)
PF09260
(DUF1966) 		5 LEU A 361
ALA A 311
ILE A 308
GLY A 457
PHE A 262
 None
 1.26A 1sv9A-2taaA:
undetectable		 1sv9A-2taaA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vn7 GLUCOAMYLASE

(Trichoderma
reesei) 		PF00686
(CBM_20)
PF00723
(Glyco_hydro_15) 		4 LEU A  57
ALA A 134
ILE A 133
GLY A 127
 None
 0.82A 1sv9A-2vn7A:
undetectable		 1sv9A-2vn7A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wch GENERAL
ODORANT-BINDING
PROTEIN 1

(Bombyx mori) 		PF01395
(PBP_GOBP) 		4 LEU A  30
ALA A  51
ILE A  52
GLY A  13
 None
None
B7M  A1145 ( 4.6A)
None
 0.76A 1sv9A-2wchA:
undetectable		 1sv9A-2wchA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wnb -

(Sus scrofa) 		PF00777
(Glyco_transf_29) 		5 LEU A 263
ILE A 278
GLY A 273
HIS A 319
PHE A 212
 None
None
C5P  A1344 (-3.2A)
GAL  A1347 (-3.9A)
GAL  A1347 (-3.9A)
 1.46A 1sv9A-2wnbA:
undetectable		 1sv9A-2wnbA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtb FATTY ACID
MULTIFUNCTIONAL
PROTEIN (ATMFP2)

(Arabidopsis
thaliana) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 ALA A 657
ILE A 656
GLY A 670
PHE A 502
 None
 0.70A 1sv9A-2wtbA:
undetectable		 1sv9A-2wtbA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn1 ALPHA-GALACTOSIDASE

(Lactobacillus
acidophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		4 LEU A 515
ILE A 479
CYH A 530
GLY A 529
 None
None
TRS  A1733 (-3.2A)
None
 0.82A 1sv9A-2xn1A:
undetectable		 1sv9A-2xn1A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xri ERI1 EXORIBONUCLEASE
3

(Homo sapiens) 		PF00929
(RNase_T) 		4 ALA A 153
ILE A 165
GLY A 309
HIS A 307
 GOL  A1338 (-3.9A)
None
MG  A1337 ( 4.3A)
None
 0.75A 1sv9A-2xriA:
undetectable		 1sv9A-2xriA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z2w WEE1-LIKE PROTEIN
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 503
ILE A 432
GLY A 413
HIS A 418
 None
 0.76A 1sv9A-2z2wA:
undetectable		 1sv9A-2z2wA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2znw SCFV10

(Mus musculus;
synthetic
construct) 		PF07686
(V-set) 		4 LEU A  33
ALA A  25
ILE A   2
GLY A  99
 None
 0.85A 1sv9A-2znwA:
undetectable		 1sv9A-2znwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3chv PROKARYOTIC DOMAIN
OF UNKNOWN FUNCTION
(DUF849) WITH A TIM
BARREL FOLD

(Ruegeria
pomeroyi) 		PF05853
(BKACE) 		4 LEU A 133
ALA A 109
GLY A  89
PHE A  68
 None
 0.74A 1sv9A-3chvA:
undetectable		 1sv9A-3chvA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejb BIOTIN BIOSYNTHESIS
CYTOCHROME P450-LIKE
ENZYME

(Bacillus
subtilis) 		PF00067
(p450) 		5 LEU B 362
ALA B 270
ILE B 267
CYH B 249
PHE B 325
 None
 1.38A 1sv9A-3ejbB:
undetectable		 1sv9A-3ejbB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fa5 PROTEIN OF UNKNOWN
FUNCTION (DUF849)

(Paracoccus
denitrificans) 		PF05853
(BKACE) 		4 LEU A 133
ALA A 109
GLY A  89
PHE A  68
 None
 0.80A 1sv9A-3fa5A:
undetectable		 1sv9A-3fa5A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fme DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 6

(Homo sapiens) 		PF00069
(Pkinase) 		5 LEU A 308
ALA A 159
ILE A 162
GLY A 244
PHE A 287
 None
 1.12A 1sv9A-3fmeA:
undetectable		 1sv9A-3fmeA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fw8 RETICULINE OXIDASE

(Eschscholzia
californica) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 ALA A 219
ILE A 220
GLY A 225
PHE A 490
 None
None
FAD  A   1 (-3.4A)
None
 0.72A 1sv9A-3fw8A:
undetectable		 1sv9A-3fw8A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fz0 NUCLEOSIDE
HYDROLASE, PUTATIVE

(Trypanosoma
brucei) 		PF01156
(IU_nuc_hydro) 		4 ALA A  19
ILE A  18
CYH A  12
GLY A  13
 None
 0.81A 1sv9A-3fz0A:
undetectable		 1sv9A-3fz0A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hee RIBOSE-5-PHOSPHATE
ISOMERASE

(Ruminiclostridium
thermocellum) 		PF02502
(LacAB_rpiB) 		4 LEU A 124
ILE A  18
GLY A  61
CYH A  58
 None
 0.79A 1sv9A-3heeA:
undetectable		 1sv9A-3heeA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hfk 4-METHYLMUCONOLACTON
E METHYLISOMERASE

(Pseudomonas
reinekei) 		PF09448
(MmlI) 		4 LEU A  98
ILE A  61
GLY A  65
HIS A  26
 4ML  A 201 ( 4.8A)
None
4ML  A 201 ( 4.2A)
4ML  A 201 (-4.1A)
 0.77A 1sv9A-3hfkA:
undetectable		 1sv9A-3hfkA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i58 O-METHYLTRANSFERASE

(Streptomyces
carzinostaticus) 		PF00891
(Methyltransf_2) 		4 LEU A 154
ALA A 243
ILE A 273
GLY A 178
 SAH  A 401 ( 4.7A)
7NA  A 402 ( 3.7A)
None
SAH  A 401 (-3.6A)
 0.83A 1sv9A-3i58A:
undetectable		 1sv9A-3i58A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ik4 MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Herpetosiphon
aurantiacus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ALA A 284
ILE A 283
GLY A 277
PHE A 316
 None
 0.75A 1sv9A-3ik4A:
undetectable		 1sv9A-3ik4A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k25 SLR1438 PROTEIN

(Synechocystis
sp. PCC 6803) 		PF01263
(Aldose_epim) 		4 ALA A 209
CYH A  71
GLY A  72
HIS A 164
 None
 0.79A 1sv9A-3k25A:
undetectable		 1sv9A-3k25A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kje CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE
COMPLEX, ACCESSORY
PROTEIN COOC

(Carboxydothermus
hydrogenoformans) 		PF01656
(CbiA) 		4 ALA A  25
ILE A  97
GLY A  19
HIS A 243
 None
 0.82A 1sv9A-3kjeA:
undetectable		 1sv9A-3kjeA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kxr MAGNESIUM
TRANSPORTER,
PUTATIVE

(Shewanella
oneidensis) 		PF00571
(CBS)
PF03448
(MgtE_N) 		4 LEU A  47
ALA A 131
ILE A  56
GLY A 161
 None
 0.65A 1sv9A-3kxrA:
undetectable		 1sv9A-3kxrA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l01 GLGA GLYCOGEN
SYNTHASE

(Pyrococcus
abyssi) 		PF00534
(Glycos_transf_1)
PF08323
(Glyco_transf_5) 		5 LEU A 374
ALA A 345
ILE A 334
GLY A 362
PHE A 412
 None
 1.39A 1sv9A-3l01A:
undetectable		 1sv9A-3l01A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mvd REGULATOR OF
CHROMOSOME
CONDENSATION

(Drosophila
melanogaster) 		PF00415
(RCC1) 		4 ALA K 265
ILE K 288
GLY K 211
HIS K 189
 None
 0.80A 1sv9A-3mvdK:
undetectable		 1sv9A-3mvdK:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n1u HYDROLASE, HAD
SUPERFAMILY,
SUBFAMILY III A

(Legionella
pneumophila) 		PF08282
(Hydrolase_3) 		4 LEU A 162
ALA A  16
ILE A  19
GLY A 132
 None
 0.85A 1sv9A-3n1uA:
undetectable		 1sv9A-3n1uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE

(Bacteroides
ovatus) 		no annotation 4 ILE A  97
GLY A 122
CYH A 148
PHE A 141
 None
 0.58A 1sv9A-3n6zA:
undetectable		 1sv9A-3n6zA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ndn O-SUCCINYLHOMOSERINE
SULFHYDRYLASE

(Mycobacterium
tuberculosis) 		PF01053
(Cys_Met_Meta_PP) 		4 ALA A 280
ILE A 283
GLY A 390
HIS A 220
 None
None
None
LLP  A 219 ( 4.8A)
 0.73A 1sv9A-3ndnA:
undetectable		 1sv9A-3ndnA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ne5 CATION EFFLUX SYSTEM
PROTEIN CUSA

(Escherichia
coli) 		PF00873
(ACR_tran) 		4 LEU A 153
ALA A 276
ILE A 275
GLY A 282
 None
 0.84A 1sv9A-3ne5A:
undetectable		 1sv9A-3ne5A:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oad RENIN

(Homo sapiens) 		PF00026
(Asp) 		4 LEU B 279
ALA B 299
ILE B 300
GLY B 316
 None
 0.78A 1sv9A-3oadB:
undetectable		 1sv9A-3oadB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pei CYTOSOL
AMINOPEPTIDASE

(Francisella
tularensis) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 ALA A 288
ILE A 287
CYH A 164
GLY A 165
 None
None
CL  A 505 ( 4.4A)
None
 0.84A 1sv9A-3peiA:
undetectable		 1sv9A-3peiA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ph3 RIBOSE-5-PHOSPHATE
ISOMERASE

(Ruminiclostridium
thermocellum) 		PF02502
(LacAB_rpiB) 		4 LEU A 124
ILE A  18
GLY A  61
CYH A  58
 None
 0.80A 1sv9A-3ph3A:
undetectable		 1sv9A-3ph3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1

(Homo sapiens) 		PF00188
(CAP) 		5 ALA A  68
ILE A  67
CYH A  37
HIS A  41
PHE A 171
 None
 1.31A 1sv9A-3q2rA:
undetectable		 1sv9A-3q2rA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q2r GLIOMA
PATHOGENESIS-RELATED
PROTEIN 1

(Homo sapiens) 		PF00188
(CAP) 		5 ILE A  67
GLY A 150
CYH A  37
HIS A  41
PHE A 171
 None
 1.47A 1sv9A-3q2rA:
undetectable		 1sv9A-3q2rA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL

(Escherichia
coli) 		PF13360
(PQQ_2) 		4 LEU A 272
ALA A 218
ILE A 227
GLY A 205
 None
 0.82A 1sv9A-3q54A:
undetectable		 1sv9A-3q54A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r4z GLYCOSYL HYDROLASE
FAMILY 32, N
TERMINAL

(Saccharophagus
degradans) 		PF04616
(Glyco_hydro_43) 		4 LEU A 210
ALA A 242
ILE A 243
GLY A 249
 None
 0.84A 1sv9A-3r4zA:
undetectable		 1sv9A-3r4zA:
16.07