SIMILAR PATTERNS OF AMINO ACIDS FOR 1SQF_A_SAMA430_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d1u PROTEIN (REVERSE
TRANSCRIPTASE)

(Murine leukemia
virus) 		PF00078
(RVT_1) 		3 PRO A 196
ASP A 200
ASP A 224
 None
 0.75A 1sqfA-1d1uA:
undetectable		 1sqfA-1d1uA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eiz FTSJ

(Escherichia
coli) 		PF01728
(FtsJ) 		3 PRO A  62
ASP A  83
ASP A 124
 SAM  A 301 (-3.4A)
SAM  A 301 (-2.8A)
SAM  A 301 (-3.6A)
 0.34A 1sqfA-1eizA:
11.7		 1sqfA-1eizA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8k ARSENITE OXIDASE

(Alcaligenes
faecalis) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 PRO A 303
ASP A 306
ASP A 277
 None
MGD  A5002 (-3.0A)
MGD  A5002 (-2.8A)
 0.73A 1sqfA-1g8kA:
2.2		 1sqfA-1g8kA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h17 FORMATE
ACETYLTRANSFERASE 1

(Escherichia
coli) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 PRO A 635
ASP A 534
ASP A 574
 None
 0.80A 1sqfA-1h17A:
undetectable		 1sqfA-1h17A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcf NEUROTROPHIN-4

(Homo sapiens) 		PF00243
(NGF) 		3 PRO A  71
ASP A  64
ASP A  18
 None
 0.80A 1sqfA-1hcfA:
undetectable		 1sqfA-1hcfA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwp GLYCEROL DEHYDRATASE
ALPHA SUBUNIT

(Klebsiella
pneumoniae) 		PF02286
(Dehydratase_LU) 		3 PRO A 139
ASP A 359
ASP A 521
 None
 0.77A 1sqfA-1iwpA:
undetectable		 1sqfA-1iwpA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1v CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA

(Escherichia
coli) 		PF08299
(Bac_DnaA_C) 		3 PRO A 423
ASP A 427
ASP A 433
 None
 0.76A 1sqfA-1j1vA:
undetectable		 1sqfA-1j1vA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sd5 PUTATIVE
ANTITERMINATOR

(Mycobacterium
tuberculosis) 		PF00072
(Response_reg)
PF03861
(ANTAR) 		3 PRO A  69
ASP A  72
ASP A  65
 None
 0.76A 1sqfA-1sd5A:
3.0		 1sqfA-1sd5A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sgq STREPTOMYCES GRISEUS
PROTEINASE B

(Streptomyces
griseus) 		PF00089
(Trypsin) 		3 PRO E  99
ASP E 102
ASP E  60
 None
 0.80A 1sqfA-1sgqE:
undetectable		 1sqfA-1sgqE:
16.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sqg SUN PROTEIN

(Escherichia
coli) 		PF01029
(NusB)
PF01189
(Methyltr_RsmB-F) 		3 PRO A 257
ASP A 277
ASP A 252
 None
 0.68A 1sqfA-1sqgA:
61.3		 1sqfA-1sqgA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sqg SUN PROTEIN

(Escherichia
coli) 		PF01029
(NusB)
PF01189
(Methyltr_RsmB-F) 		3 PRO A 257
ASP A 277
ASP A 322
 None
 0.44A 1sqfA-1sqgA:
61.3		 1sqfA-1sqgA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmo TRIMETHYLAMINE
N-OXIDE REDUCTASE

(Shewanella
massilia) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 PRO A 246
ASP A 249
ASP A 227
 None
2MD  A 800 (-3.1A)
2MD  A 800 (-2.8A)
 0.81A 1sqfA-1tmoA:
undetectable		 1sqfA-1tmoA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uc4 DIOL DEHYDRASE ALPHA
SUBUNIT

(Klebsiella
oxytoca) 		PF02286
(Dehydratase_LU) 		3 PRO A 138
ASP A 358
ASP A 520
 None
 0.73A 1sqfA-1uc4A:
2.1		 1sqfA-1uc4A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w7w NUCLEOSIDE
DIPHOSPHATE KINASE

(Pisum sativum) 		PF00334
(NDK) 		3 PRO A 122
ASP A 120
ASP A 127
 None
 0.75A 1sqfA-1w7wA:
undetectable		 1sqfA-1w7wA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrs D-LYSINE
5,6-AMINOMUTASE
ALPHA SUBUNIT

(Acetoanaerobium
sticklandii) 		PF09043
(Lys-AminoMut_A) 		3 PRO A  57
ASP A  52
ASP A  64
 None
None
5AD  B 500 ( 4.7A)
 0.68A 1sqfA-1xrsA:
undetectable		 1sqfA-1xrsA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yks GENOME POLYPROTEIN
[CONTAINS:
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT]

(Yellow fever
virus) 		PF00271
(Helicase_C)
PF07652
(Flavi_DEAD) 		3 PRO A 362
ASP A 359
ASP A 474
 None
 0.79A 1sqfA-1yksA:
2.3		 1sqfA-1yksA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b9e NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 PRO A 237
ASP A 258
ASP A 305
 SAM  A1201 (-3.7A)
SAM  A1201 (-2.6A)
SAM  A1201 (-3.7A)
 0.41A 1sqfA-2b9eA:
26.7		 1sqfA-2b9eA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bol SMALL HEAT SHOCK
PROTEIN

(Taenia saginata) 		PF00011
(HSP20) 		3 PRO A 199
ASP A 102
ASP A  49
 None
 0.75A 1sqfA-2bolA:
undetectable		 1sqfA-2bolA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ckn BASIC FIBROBLAST
GROWTH FACTOR
RECEPTOR 1

(Mus musculus) 		PF00047
(ig) 		3 PRO A  82
ASP A  84
ASP A  79
 None
 0.66A 1sqfA-2cknA:
undetectable		 1sqfA-2cknA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpm PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1)

(Streptococcus
pneumoniae) 		PF02086
(MethyltransfD12) 		3 PRO A  42
ASP A  62
ASP A 177
 None
SAM  A 300 (-2.8A)
SAM  A 300 (-4.1A)
 0.77A 1sqfA-2dpmA:
8.1		 1sqfA-2dpmA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f8l HYPOTHETICAL PROTEIN
LMO1582

(Listeria
monocytogenes) 		PF02384
(N6_Mtase) 		3 PRO A 125
ASP A 154
ASP A 180
 None
SAM  A 400 (-2.7A)
SAM  A 400 (-3.4A)
 0.78A 1sqfA-2f8lA:
11.8		 1sqfA-2f8lA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jir PERIPLASMIC NITRATE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		3 PRO A 222
ASP A 225
ASP A 204
 MGD  A 812 (-4.5A)
MGD  A 812 (-3.4A)
MGD  A 812 (-2.7A)
 0.43A 1sqfA-2jirA:
2.5		 1sqfA-2jirA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nyu PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2

(Homo sapiens) 		PF01728
(FtsJ) 		3 PRO A  33
ASP A  62
ASP A 104
 SAM  A 201 (-3.4A)
SAM  A 201 (-2.8A)
SAM  A 201 (-3.7A)
 0.31A 1sqfA-2nyuA:
11.8		 1sqfA-2nyuA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p35 TRANS-ACONITATE
2-METHYLTRANSFERASE

(Agrobacterium
fabrum) 		PF13489
(Methyltransf_23) 		3 PRO A  41
ASP A  61
ASP A  36
 None
SAH  A 301 (-2.7A)
SAH  A 301 ( 4.4A)
 0.81A 1sqfA-2p35A:
13.2		 1sqfA-2p35A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4v TRANSCRIPTION
ELONGATION FACTOR
GREB

(Escherichia
coli) 		PF01272
(GreA_GreB)
PF03449
(GreA_GreB_N) 		3 PRO A   4
ASP A 109
ASP A 121
 None
 0.76A 1sqfA-2p4vA:
undetectable		 1sqfA-2p4vA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pg8 DPGC

(Streptomyces
toyocaensis) 		PF00378
(ECH_1) 		3 PRO A 147
ASP A 202
ASP A 195
 None
 0.74A 1sqfA-2pg8A:
undetectable		 1sqfA-2pg8A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2plw RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE

(Plasmodium
falciparum) 		PF01728
(FtsJ) 		3 PRO A  33
ASP A  55
ASP A 113
 SAM  A 203 (-3.5A)
SAM  A 203 (-2.8A)
SAM  A 203 (-3.6A)
 0.36A 1sqfA-2plwA:
12.4		 1sqfA-2plwA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pv7 T-PROTEIN [INCLUDES:
CHORISMATE MUTASE
(EC 5.4.99.5) (CM)
AND PREPHENATE
DEHYDROGENASE (EC
1.3.1.12) (PDH)]

(Haemophilus
influenzae) 		PF02153
(PDH) 		3 PRO A 153
ASP A 308
ASP A 302
 NAD  A 400 (-4.4A)
None
NAD  A 400 ( 4.7A)
 0.78A 1sqfA-2pv7A:
3.9		 1sqfA-2pv7A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rhp THROMBOSPONDIN-2

(Homo sapiens) 		PF02412
(TSP_3)
PF05735
(TSP_C)
PF07645
(EGF_CA)
PF12947
(EGF_3) 		3 PRO A 906
ASP A 903
ASP A 900
 None
CA  A1174 ( 2.5A)
CA  A   8 (-2.3A)
 0.76A 1sqfA-2rhpA:
undetectable		 1sqfA-2rhpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2tpt THYMIDINE
PHOSPHORYLASE

(Escherichia
coli) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		3 PRO A 398
ASP A 394
ASP A 391
 None
 0.50A 1sqfA-2tptA:
undetectable		 1sqfA-2tptA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vp3 VP39

(Vaccinia virus) 		PF01358
(PARP_regulatory) 		3 PRO A  71
ASP A  95
ASP A 138
 SAH  A 400 (-3.7A)
SAH  A 400 (-2.6A)
SAH  A 400 (-3.7A)
 0.54A 1sqfA-2vp3A:
7.7		 1sqfA-2vp3A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vw8 PA1000

(Pseudomonas
aeruginosa) 		PF00753
(Lactamase_B) 		3 PRO A  23
ASP A  44
ASP A  73
 None
None
FE2  A 401 ( 2.8A)
 0.68A 1sqfA-2vw8A:
undetectable		 1sqfA-2vw8A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x66 PRNB

(Pseudomonas
fluorescens) 		PF08933
(DUF1864) 		3 PRO A 198
ASP A 136
ASP A 203
 None
 0.77A 1sqfA-2x66A:
undetectable		 1sqfA-2x66A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt9 PUTATIVE SIGNAL
TRANSDUCTION PROTEIN
GARA

(Mycolicibacterium
smegmatis) 		PF00498
(FHA) 		3 PRO B  74
ASP B  72
ASP B  85
 None
 0.76A 1sqfA-2xt9B:
undetectable		 1sqfA-2xt9B:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xva TELLURITE RESISTANCE
PROTEIN TEHB

(Escherichia
coli) 		PF03848
(TehB) 		3 PRO A  31
ASP A  97
ASP A  54
 None
 0.64A 1sqfA-2xvaA:
11.5		 1sqfA-2xvaA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvg ALPHA XYLOSIDASE

(Cellvibrio
japonicus) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF17137
(DUF5110) 		3 PRO A 162
ASP A 159
ASP A 164
 None
None
SO4  A1995 (-2.7A)
 0.61A 1sqfA-2xvgA:
undetectable		 1sqfA-2xvgA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xvs TETRATRICOPEPTIDE
REPEAT PROTEIN 5

(Homo sapiens) 		PF16669
(TTC5_OB) 		3 PRO A 363
ASP A 361
ASP A 359
 None
 0.79A 1sqfA-2xvsA:
undetectable		 1sqfA-2xvsA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y35 LD22664P

(Drosophila
melanogaster) 		PF03159
(XRN_N) 		3 PRO A 427
ASP A 429
ASP A 471
 None
 0.71A 1sqfA-2y35A:
2.1		 1sqfA-2y35A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yxl 450AA LONG
HYPOTHETICAL FMU
PROTEIN

(Pyrococcus
horikoshii) 		PF01189
(Methyltr_RsmB-F)
PF17125
(Methyltr_RsmF_N) 		3 PRO A 270
ASP A 291
ASP A 337
 SFG  A5748 (-3.6A)
SFG  A5748 (-2.9A)
SFG  A5748 (-3.6A)
 0.48A 1sqfA-2yxlA:
40.8		 1sqfA-2yxlA:
29.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0f XYLOGLUCANASE

(Geotrichum sp.
M128) 		no annotation 3 PRO A 260
ASP A 258
ASP A 324
 None
 0.70A 1sqfA-3a0fA:
undetectable		 1sqfA-3a0fA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3p METHYLTRANSFERASE

(Geobacter
sulfurreducens) 		PF01596
(Methyltransf_3) 		3 PRO A  62
ASP A  87
ASP A 115
 None
EDO  A 215 (-3.0A)
None
 0.72A 1sqfA-3c3pA:
10.7		 1sqfA-3c3pA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmm UBIQUITIN-ACTIVATING
ENZYME E1 1

(Saccharomyces
cerevisiae) 		PF00899
(ThiF)
PF09358
(E1_UFD)
PF10585
(UBA_e1_thiolCys)
PF16190
(E1_FCCH)
PF16191
(E1_4HB) 		3 PRO A  70
ASP A  67
ASP A  75
 None
 0.73A 1sqfA-3cmmA:
5.0		 1sqfA-3cmmA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dou RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J

(Thermoplasma
volcanium) 		PF01728
(FtsJ) 		3 PRO A  49
ASP A  67
ASP A 111
 SAM  A   1 (-3.5A)
SAM  A   1 (-2.7A)
SAM  A   1 (-3.7A)
 0.35A 1sqfA-3douA:
7.2		 1sqfA-3douA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f1k UNCHARACTERIZED
OXIDOREDUCTASE YCIK

(Escherichia
coli) 		PF00106
(adh_short) 		3 PRO A 114
ASP A 105
ASP A 119
 None
 0.66A 1sqfA-3f1kA:
8.0		 1sqfA-3f1kA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fby CARTILAGE OLIGOMERIC
MATRIX PROTEIN

(Homo sapiens) 		PF02412
(TSP_3)
PF05735
(TSP_C) 		3 PRO A 478
ASP A 475
ASP A 472
 None
CA  A 823 ( 2.7A)
CA  A 821 (-2.7A)
 0.77A 1sqfA-3fbyA:
undetectable		 1sqfA-3fbyA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g20 TYPE II SECRETION
PROTEIN

(Escherichia
coli) 		PF08334
(T2SSG) 		3 PRO A 103
ASP A 110
ASP A 108
 None
 0.73A 1sqfA-3g20A:
undetectable		 1sqfA-3g20A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldu PUTATIVE METHYLASE

(Clostridioides
difficile) 		PF01170
(UPF0020)
PF02926
(THUMP) 		3 PRO A 199
ASP A 261
ASP A 289
 None
GTP  A 383 (-3.0A)
GTP  A 383 ( 3.8A)
 0.77A 1sqfA-3lduA:
10.6		 1sqfA-3lduA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lhl PUTATIVE AGMATINASE

(Clostridioides
difficile) 		PF00491
(Arginase) 		3 PRO A  59
ASP A  62
ASP A  64
 None
 0.81A 1sqfA-3lhlA:
undetectable		 1sqfA-3lhlA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mam OSMOPROTECTION
PROTEIN (PROX)

(Archaeoglobus
fulgidus) 		PF04069
(OpuAC) 		3 PRO A 213
ASP A 206
ASP A 151
 None
 0.66A 1sqfA-3mamA:
undetectable		 1sqfA-3mamA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ml0 PENICILLIN G
ACYLASE, ALPHA
SUBUNIT

(Alcaligenes
faecalis) 		PF01804
(Penicil_amidase) 		3 PRO A 129
ASP A  42
ASP A 134
 None
 0.69A 1sqfA-3ml0A:
undetectable		 1sqfA-3ml0A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mve UPF0255 PROTEIN
VV1_0328

(Vibrio
vulnificus) 		PF06500
(DUF1100) 		3 PRO A 298
ASP A 373
ASP A 366
 EDO  A 417 ( 4.7A)
None
None
 0.81A 1sqfA-3mveA:
undetectable		 1sqfA-3mveA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		3 PRO A 949
ASP A 708
ASP A 931
 None
 0.79A 1sqfA-3opyA:
undetectable		 1sqfA-3opyA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poh ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F1

(Bacteroides
thetaiotaomicron) 		PF08522
(DUF1735) 		3 PRO A 469
ASP A 466
ASP A 475
 None
 0.66A 1sqfA-3pohA:
undetectable		 1sqfA-3pohA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vm5 ALPHA-AMYLASE

(Oryzias latipes) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C) 		3 PRO A 130
ASP A 135
ASP A 125
 None
 0.77A 1sqfA-3vm5A:
undetectable		 1sqfA-3vm5A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbk EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5B

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		3 PRO A 386
ASP A 391
ASP A 416
 None
 0.74A 1sqfA-3wbkA:
undetectable		 1sqfA-3wbkA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wj7 PUTATIVE
OXIDOREDUCTASE

(Gluconobacter
oxydans) 		PF01370
(Epimerase) 		3 PRO A 320
ASP A 219
ASP A 327
 None
 0.80A 1sqfA-3wj7A:
6.3		 1sqfA-3wj7A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zg4 ERFK/YBIS/YCFS/YNHG

(Enterococcus
faecium) 		PF03734
(YkuD) 		3 PRO A 406
ASP A 422
ASP A 390
 None
 0.78A 1sqfA-3zg4A:
undetectable		 1sqfA-3zg4A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dkj CYTOSINE-SPECIFIC
METHYLTRANSFERASE

(Mycoplasma
penetrans) 		PF00145
(DNA_methylase) 		3 PRO A 258
ASP A 223
ASP A 263
 None
 0.74A 1sqfA-4dkjA:
7.1		 1sqfA-4dkjA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dvg DIAPHANOUS PROTEIN

(Entamoeba
histolytica) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 PRO B 317
ASP B 315
ASP B 267
 None
 0.74A 1sqfA-4dvgB:
undetectable		 1sqfA-4dvgB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewt PEPTIDASE,
M20/M25/M40 FAMILY

(Staphylococcus
aureus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 PRO A 142
ASP A 296
ASP A 334
 None
 0.76A 1sqfA-4ewtA:
undetectable		 1sqfA-4ewtA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzv PUTATIVE
METHYLTRANSFERASE
NSUN4

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 PRO A 185
ASP A 204
ASP A 255
 SAM  A 401 (-3.6A)
SAM  A 401 (-2.9A)
SAM  A 401 (-3.7A)
 0.25A 1sqfA-4fzvA:
27.1		 1sqfA-4fzvA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hlj ROUNDABOUT HOMOLOG 1

(Homo sapiens) 		PF00041
(fn3) 		3 PRO A 877
ASP A 872
ASP A 882
 None
 0.74A 1sqfA-4hljA:
undetectable		 1sqfA-4hljA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iob DIGUANYLATE CYCLASE
TPBB

(Pseudomonas
aeruginosa) 		PF00990
(GGDEF) 		3 PRO A 338
ASP A 322
ASP A 344
 None
 0.75A 1sqfA-4iobA:
undetectable		 1sqfA-4iobA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irt UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF15892
(BNR_4) 		3 PRO A 281
ASP A 276
ASP A 303
 None
 0.75A 1sqfA-4irtA:
undetectable		 1sqfA-4irtA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k6l PUTATIVE
PERTUSSIS-LIKE TOXIN
SUBUNIT

(Salmonella
enterica) 		PF02917
(Pertussis_S1) 		3 PRO G  29
ASP G  26
ASP G  36
 None
 0.74A 1sqfA-4k6lG:
undetectable		 1sqfA-4k6lG:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n3s EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5B

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		3 PRO A 786
ASP A 791
ASP A 816
 None
 0.73A 1sqfA-4n3sA:
undetectable		 1sqfA-4n3sA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nmn REPLICATIVE DNA
HELICASE

(Aquifex
aeolicus) 		PF00772
(DnaB)
PF03796
(DnaB_C) 		3 PRO A 290
ASP A 287
ASP A 296
 None
 0.80A 1sqfA-4nmnA:
undetectable		 1sqfA-4nmnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4npk EXTENDED
SYNAPTOTAGMIN-2

(Homo sapiens) 		PF00168
(C2) 		3 PRO A 463
ASP A 466
ASP A 413
 None
CA  A 803 (-3.1A)
CA  A 801 (-3.3A)
 0.77A 1sqfA-4npkA:
undetectable		 1sqfA-4npkA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4opf NRPS/PKS

(Streptomyces
albus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 PRO A6380
ASP A6371
ASP A6512
 None
 0.71A 1sqfA-4opfA:
undetectable		 1sqfA-4opfA:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2b ENDO-1,4-BETA-D-GLUC
ANASE

(Pseudomonas
putida) 		PF01270
(Glyco_hydro_8) 		3 PRO A 219
ASP A 241
ASP A 286
 None
 0.77A 1sqfA-4q2bA:
undetectable		 1sqfA-4q2bA:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		3 PRO A 358
ASP A 450
ASP A 483
 None
 0.76A 1sqfA-4q2cA:
undetectable		 1sqfA-4q2cA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r1u CINNAMOYL COA
REDUCTASE

(Medicago
truncatula) 		PF01370
(Epimerase) 		3 PRO A 295
ASP A 221
ASP A 302
 None
 0.79A 1sqfA-4r1uA:
5.7		 1sqfA-4r1uA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4txv THIOL:DISULFIDE
INTERCHANGE PROTEIN
TLPA

(Bradyrhizobium
diazoefficiens) 		PF08534
(Redoxin) 		3 PRO A  87
ASP A  82
ASP A  92
 None
 0.72A 1sqfA-4txvA:
undetectable		 1sqfA-4txvA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uj6 SURFACE LAYER
PROTEIN

(Geobacillus
stearothermophilus) 		PF13205
(Big_5) 		3 PRO A 372
ASP A 443
ASP A 491
 None
 0.81A 1sqfA-4uj6A:
undetectable		 1sqfA-4uj6A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4whi BETA-LACTAMASE

(Mycobacterium
tuberculosis) 		PF11954
(DUF3471) 		3 PRO A 444
ASP A 489
ASP A 491
 None
 0.60A 1sqfA-4whiA:
undetectable		 1sqfA-4whiA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wmj GLUCOSE-6-PHOSPHATE
ISOMERASE

(Colias
eurytheme) 		PF00342
(PGI) 		3 PRO A 487
ASP A  52
ASP A 301
 None
 0.73A 1sqfA-4wmjA:
undetectable		 1sqfA-4wmjA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xj5 CYCLIC AMP-GMP
SYNTHASE

(Vibrio cholerae) 		no annotation 3 PRO A 261
ASP A 345
ASP A 266
 GH3  A1013 ( 3.9A)
GH3  A1014 ( 4.4A)
None
 0.77A 1sqfA-4xj5A:
undetectable		 1sqfA-4xj5A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xj6 VC0179-LIKE PROTEIN

(Escherichia
coli) 		no annotation 3 PRO A 257
ASP A 341
ASP A 262
 GH3  A 504 ( 4.1A)
None
None
 0.52A 1sqfA-4xj6A:
undetectable		 1sqfA-4xj6A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9c PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA

(Escherichia
coli) 		PF02917
(Pertussis_S1) 		3 PRO A  14
ASP A  11
ASP A  21
 None
 0.80A 1sqfA-4z9cA:
undetectable		 1sqfA-4z9cA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a5g FORMATE--TETRAHYDROF
OLATE LIGASE

(Tepidanaerobacter
acetatoxydans) 		PF01268
(FTHFS) 		3 PRO A 233
ASP A 228
ASP A 238
 None
 0.80A 1sqfA-5a5gA:
undetectable		 1sqfA-5a5gA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5brj TWO COMPONENT
RESPONSE REGULATOR

(Agrobacterium
tumefaciens) 		PF00072
(Response_reg) 		3 PRO A  69
ASP A  72
ASP A  65
 None
None
MG  A 201 (-2.5A)
 0.77A 1sqfA-5brjA:
3.2		 1sqfA-5brjA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d95 AMINOTRANSFERASE
CLASS-III

(Sphaerobacter
thermophilus) 		PF00202
(Aminotran_3) 		3 PRO A 337
ASP A 341
ASP A 263
 None
 0.74A 1sqfA-5d95A:
undetectable		 1sqfA-5d95A:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dih MICROCOMPARTMENTS
PROTEIN

(Haliangium
ochraceum) 		PF00936
(BMC) 		3 PRO A   5
ASP A   9
ASP A 106
 None
 0.67A 1sqfA-5dihA:
undetectable		 1sqfA-5dihA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fji BETA-GLUCOSIDASE

(Aspergillus
fumigatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 PRO A  32
ASP A 333
ASP A  35
 None
None
EDO  A1874 ( 4.5A)
 0.64A 1sqfA-5fjiA:
undetectable		 1sqfA-5fjiA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjj BETA-GLUCOSIDASE

(Aspergillus
oryzae) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 PRO A  33
ASP A 333
ASP A  36
 None
 0.41A 1sqfA-5fjjA:
undetectable		 1sqfA-5fjjA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5g PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT

(Escherichia
coli;
Escherichia
coli) 		PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C)
PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		3 PRO B 128
ASP B 124
ASP C 645
 None
 0.77A 1sqfA-5g5gB:
undetectable		 1sqfA-5g5gB:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hi8 ANTENNA PROTEIN

(Prochlorococcus
phage P-HM1) 		PF06206
(CpeT) 		3 PRO A  74
ASP A  77
ASP A  60
 None
MG  A 201 ( 4.2A)
None
 0.56A 1sqfA-5hi8A:
undetectable		 1sqfA-5hi8A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mul NEURAMINIDASE

(Bacteroides
thetaiotaomicron) 		PF15892
(BNR_4) 		3 PRO A 281
ASP A 276
ASP A 303
 None
 0.78A 1sqfA-5mulA:
undetectable		 1sqfA-5mulA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mvh BACCELL_00856

(Bacteroides
cellulosilyticus) 		PF15892
(BNR_4) 		3 PRO A 281
ASP A 276
ASP A 303
 None
 0.73A 1sqfA-5mvhA:
undetectable		 1sqfA-5mvhA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5pep PEPSIN

(Sus scrofa) 		PF00026
(Asp) 		3 PRO A 116
ASP A 118
ASP A  52
 None
 0.81A 1sqfA-5pepA:
undetectable		 1sqfA-5pepA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tta PUTATIVE EXPORTED
PROTEIN

(Clostridioides
difficile) 		no annotation 3 PRO A 150
ASP A 120
ASP A 218
 None
 0.79A 1sqfA-5ttaA:
undetectable		 1sqfA-5ttaA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5um6 UBIQUITIN-ACTIVATING
ENZYME E1 1

(Schizosaccharomyces
pombe) 		PF00899
(ThiF)
PF09358
(E1_UFD)
PF10585
(UBA_e1_thiolCys)
PF16190
(E1_FCCH)
PF16191
(E1_4HB) 		3 PRO A  71
ASP A  68
ASP A  76
 None
 0.78A 1sqfA-5um6A:
4.0		 1sqfA-5um6A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vha DEAH
(ASP-GLU-ALA-HIS)
BOX POLYPEPTIDE 36

(Bos taurus) 		no annotation 3 PRO A 543
ASP A 564
ASP A 490
 None
 0.74A 1sqfA-5vhaA:
2.4		 1sqfA-5vhaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wwt PUTATIVE
METHYLTRANSFERASE
NSUN6

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		3 PRO A 245
ASP A 266
ASP A 323
 C  C  72 ( 4.7A)
None
C  C  72 ( 2.8A)
 0.40A 1sqfA-5wwtA:
17.4		 1sqfA-5wwtA:
28.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6x MRNA CAPPING ENZYME
P5

(Rice dwarf
virus) 		no annotation 3 PRO C 290
ASP C 308
ASP C 359
 None
 0.38A 1sqfA-5x6xC:
4.0		 1sqfA-5x6xC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ct0 DIHYDROLIPOYLLYSINE-
RESIDUE
ACETYLTRANSFERASE
COMPONENT OF
PYRUVATE
DEHYDROGENASE
COMPLEX,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 3 PRO 0 599
ASP 0 607
ASP 0 601
 None
 0.71A 1sqfA-6ct00:
undetectable		 1sqfA-6ct00:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cza -

(-) 		no annotation 3 PRO A 273
ASP A 276
ASP A 255
 MGD  A 902 (-4.0A)
MGD  A 902 (-1.9A)
MGD  A 902 (-2.3A)
 0.81A 1sqfA-6czaA:
undetectable		 1sqfA-6czaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6q EXOSOME COMPLEX
COMPONENT RRP4

(Homo sapiens) 		no annotation 3 PRO H 190
ASP H 188
ASP H 253
 None
 0.78A 1sqfA-6d6qH:
undetectable		 1sqfA-6d6qH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f1d COMPLEMENT C1R
SUBCOMPONENT

(Homo sapiens) 		no annotation 3 PRO A 199
ASP A 236
ASP A 277
 None
CA  A 300 (-2.2A)
None
 0.77A 1sqfA-6f1dA:
undetectable		 1sqfA-6f1dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Cyanidioschyzon
merolae) 		no annotation 3 PRO B 546
ASP B 558
ASP B 550
 None
 0.58A 1sqfA-6fosB:
undetectable		 1sqfA-6fosB:
undetectable