SIMILAR PATTERNS OF AMINO ACIDS FOR 1SN0_C_T44C601_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bk6 KARYOPHERIN ALPHA

(Saccharomyces
cerevisiae) 		PF00514
(Arm)
PF16186
(Arm_3) 		5 LEU A 388
LEU A 384
LYS A 358
GLU A 355
ALA A 361
 None
 1.36A 1sn0A-1bk6A:
undetectable
1sn0C-1bk6A:
undetectable		 1sn0A-1bk6A:
18.29
1sn0C-1bk6A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ctm CYTOCHROME F

(Brassica rapa) 		PF01333
(Apocytochr_F_C)
PF16639
(Apocytochr_F_N) 		5 LEU A  75
ALA A  73
LEU A 113
GLU A  34
ALA A  47
 None
 1.45A 1sn0A-1ctmA:
0.0
1sn0C-1ctmA:
0.0		 1sn0A-1ctmA:
18.82
1sn0C-1ctmA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e33 ARYLSULFATASE A

(Homo sapiens) 		PF00884
(Sulfatase)
PF14707
(Sulfatase_C) 		5 LEU P 428
LEU P 441
LYS P 457
LEU P 453
ALA P 455
 None
 1.36A 1sn0A-1e33P:
0.0
1sn0C-1e33P:
0.0		 1sn0A-1e33P:
14.11
1sn0C-1e33P:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l7p PHOSPHOSERINE
PHOSPHATASE

(Methanocaldococcus
jannaschii) 		PF12710
(HAD) 		5 LEU A   9
ALA A 152
LYS A 177
LEU A 159
ALA A 178
 None
 1.06A 1sn0A-1l7pA:
0.0
1sn0C-1l7pA:
undetectable		 1sn0A-1l7pA:
17.27
1sn0C-1l7pA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A

(Escherichia
coli) 		no annotation 5 LEU A 154
ALA A 142
LEU A 144
GLU A 168
ALA A 171
 None
 1.47A 1sn0A-1oy1A:
undetectable
1sn0C-1oy1A:
0.0		 1sn0A-1oy1A:
19.30
1sn0C-1oy1A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pz3 ALPHA-L-ARABINOFURAN
OSIDASE

(Geobacillus
stearothermophilus) 		PF06964
(Alpha-L-AF_C) 		5 LEU A 129
ALA A 126
LEU A 172
GLU A  82
ALA A 137
 None
 1.34A 1sn0A-1pz3A:
0.3
1sn0C-1pz3A:
0.1		 1sn0A-1pz3A:
13.29
1sn0C-1pz3A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qs0 2-OXOISOVALERATE
DEHYDROGENASE
ALPHA-SUBUNIT

(Pseudomonas
putida) 		PF00676
(E1_dh)
PF12573
(OxoDH_E1alpha_N) 		5 LEU A 154
ALA A  97
LEU A 153
LYS A 370
ALA A 372
 None
 1.34A 1sn0A-1qs0A:
0.0
1sn0C-1qs0A:
0.0		 1sn0A-1qs0A:
16.33
1sn0C-1qs0A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrm LACTALDEHYDE
REDUCTASE

(Escherichia
coli) 		PF00465
(Fe-ADH) 		5 LEU A  81
ALA A 106
LEU A 122
GLU A 115
ALA A 117
 None
 1.20A 1sn0A-1rrmA:
0.0
1sn0C-1rrmA:
0.0		 1sn0A-1rrmA:
16.24
1sn0C-1rrmA:
16.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1sn2 TRANSTHYRETIN

(Sparus aurata) 		PF00576
(Transthyretin) 		5 MET A  13
LYS A  15
LEU A  17
GLU A  54
ALA A 108
 None
 0.15A 1sn0A-1sn2A:
25.2
1sn0C-1sn2A:
23.1		 1sn0A-1sn2A:
100.00
1sn0C-1sn2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tfp TRANSTHYRETIN

(Gallus gallus) 		PF00576
(Transthyretin) 		5 MET A  13
LYS A  15
LEU A  17
GLU A  54
ALA A 108
 None
 0.36A 1sn0A-1tfpA:
18.6
1sn0C-1tfpA:
18.4		 1sn0A-1tfpA:
62.31
1sn0C-1tfpA:
62.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ufm COP9 COMPLEX SUBUNIT
4

(Mus musculus) 		PF01399
(PCI) 		5 LEU A 324
LEU A 328
LEU A 310
GLU A 362
ALA A 312
 None
 1.40A 1sn0A-1ufmA:
undetectable
1sn0C-1ufmA:
undetectable		 1sn0A-1ufmA:
22.31
1sn0C-1ufmA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wa5 IMPORTIN ALPHA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3) 		5 LEU B 388
LEU B 384
LYS B 358
GLU B 355
ALA B 361
 None
 1.26A 1sn0A-1wa5B:
undetectable
1sn0C-1wa5B:
undetectable		 1sn0A-1wa5B:
13.51
1sn0C-1wa5B:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wy0 GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00348
(polyprenyl_synt) 		5 LEU A 318
LYS A 335
LEU A 332
GLU A 339
ALA A 334
 None
 1.45A 1sn0A-1wy0A:
undetectable
1sn0C-1wy0A:
undetectable		 1sn0A-1wy0A:
17.87
1sn0C-1wy0A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iw1 LIPOPOLYSACCHARIDE
CORE BIOSYNTHESIS
PROTEIN RFAG

(Escherichia
coli) 		PF00534
(Glycos_transf_1)
PF13439
(Glyco_transf_4) 		5 LEU A 275
LEU A 231
LEU A 221
GLU A 329
ALA A 217
 None
 1.17A 1sn0A-2iw1A:
undetectable
1sn0C-2iw1A:
undetectable		 1sn0A-2iw1A:
16.80
1sn0C-2iw1A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nx9 OXALOACETATE
DECARBOXYLASE 2,
SUBUNIT ALPHA

(Vibrio cholerae) 		PF00682
(HMGL-like)
PF02436
(PYC_OADA) 		5 LEU A  86
LEU A  92
LEU A 438
GLU A 107
ALA A 109
 None
 1.20A 1sn0A-2nx9A:
undetectable
1sn0C-2nx9A:
undetectable		 1sn0A-2nx9A:
15.30
1sn0C-2nx9A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ocf ESTROGEN RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		5 LEU A 544
ALA A 546
MET A 388
LYS A 382
GLU A 385
 None
None
None
CME  A 381 ( 3.4A)
CME  A 381 ( 4.3A)
 1.45A 1sn0A-2ocfA:
undetectable
1sn0C-2ocfA:
undetectable		 1sn0A-2ocfA:
17.45
1sn0C-2ocfA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rf7 CYTOCHROME C-552

(Escherichia
coli) 		PF02335
(Cytochrom_C552) 		5 LEU A 419
LEU A 420
LEU A 358
GLU A 364
ALA A 362
 None
 1.48A 1sn0A-2rf7A:
undetectable
1sn0C-2rf7A:
undetectable		 1sn0A-2rf7A:
15.24
1sn0C-2rf7A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y2w ARABINOFURANOSIDASE

(Bifidobacterium
longum) 		PF06964
(Alpha-L-AF_C) 		5 LEU A 554
ALA A 552
LEU A 494
GLU A 436
ALA A 483
 None
 1.30A 1sn0A-2y2wA:
undetectable
1sn0C-2y2wA:
undetectable		 1sn0A-2y2wA:
12.72
1sn0C-2y2wA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana) 		PF00348
(polyprenyl_synt) 		5 LEU A 158
ALA A 156
LEU A 146
LYS A 203
ALA A 204
 None
 1.36A 1sn0A-3aq0A:
undetectable
1sn0C-3aq0A:
undetectable		 1sn0A-3aq0A:
15.52
1sn0C-3aq0A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0h UNCHARACTERIZED
PROTEIN

(Chlorobaculum
tepidum) 		PF06445
(GyrI-like) 		5 LEU A 116
LYS A  96
LEU A  11
GLU A 157
ALA A  97
 None
 1.46A 1sn0A-3e0hA:
undetectable
1sn0C-3e0hA:
undetectable		 1sn0A-3e0hA:
22.54
1sn0C-3e0hA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv3 GALECTIN 9 SHORT
ISOFORM VARIANT

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		5 LEU A 304
LEU A 203
LYS A 286
LEU A 279
GLU A 296
 None
 1.39A 1sn0A-3nv3A:
undetectable
1sn0C-3nv3A:
undetectable		 1sn0A-3nv3A:
19.59
1sn0C-3nv3A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozb METHYLTHIOADENOSINE
PHOSPHORYLASE

(Pseudomonas
aeruginosa) 		PF01048
(PNP_UDP_1) 		5 ALA A  86
LEU A  84
LEU A  51
GLU A  60
ALA A  19
 None
None
None
SO4  A 262 (-3.1A)
None
 1.24A 1sn0A-3ozbA:
undetectable
1sn0C-3ozbA:
undetectable		 1sn0A-3ozbA:
21.88
1sn0C-3ozbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rx8 CELLULASE

(Alicyclobacillus
acidocaldarius) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		5 LEU A 162
ALA A 164
LEU A  96
GLU A 192
ALA A 194
 None
 1.26A 1sn0A-3rx8A:
4.5
1sn0C-3rx8A:
4.7		 1sn0A-3rx8A:
14.23
1sn0C-3rx8A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfz APOPTOTIC PEPTIDASE
ACTIVATING FACTOR 1

(Mus musculus) 		PF00400
(WD40)
PF00931
(NB-ARC)
PF12894
(ANAPC4_WD40) 		5 LYS A 585
LEU A 582
ALA A 584
LEU A 568
GLU A 572
 None
 1.44A 1sn0A-3sfzA:
undetectable
1sn0C-3sfzA:
1.9		 1sn0A-3sfzA:
7.57
1sn0C-3sfzA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umm PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE

(Salmonella
enterica) 		PF02769
(AIRS_C)
PF13507
(GATase_5) 		5 LEU A   5
LEU A  59
MET A   1
GLU A 147
ALA A  41
 None
 1.25A 1sn0A-3ummA:
undetectable
1sn0C-3ummA:
undetectable		 1sn0A-3ummA:
7.13
1sn0C-3ummA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vov GLUCOKINASE

(Thermus
thermophilus) 		PF00480
(ROK) 		5 LYS A  26
LEU A  23
ALA A  50
LEU A   6
ALA A 290
 None
 1.44A 1sn0A-3vovA:
undetectable
1sn0C-3vovA:
undetectable		 1sn0A-3vovA:
18.64
1sn0C-3vovA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f21 CARBOXYLESTERASE/PHO
SPHOLIPASE FAMILY
PROTEIN

(Francisella
tularensis) 		PF02230
(Abhydrolase_2) 		5 LEU A 181
LEU A 185
LEU A 163
GLU A 208
ALA A 138
 None
 1.26A 1sn0A-4f21A:
undetectable
1sn0C-4f21A:
undetectable		 1sn0A-4f21A:
19.67
1sn0C-4f21A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rxm POSSIBLE SUGAR ABC
SUPERFAMILY ATP
BINDING CASSETTE
TRANSPORTER, BINDING
PROTEIN

(Mannheimia
haemolytica) 		PF13407
(Peripla_BP_4) 		5 LEU A 259
LEU A 297
LYS A 137
GLU A 171
ALA A 138
 None
 1.45A 1sn0A-4rxmA:
undetectable
1sn0C-4rxmA:
undetectable		 1sn0A-4rxmA:
18.49
1sn0C-4rxmA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uuo CYTOSOLIC MALATE
DEHYDROGENASE

(Trichomonas
vaginalis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 LEU A 332
ALA A 140
LYS A 323
LEU A 136
ALA A 326
 None
 1.33A 1sn0A-4uuoA:
undetectable
1sn0C-4uuoA:
undetectable		 1sn0A-4uuoA:
17.16
1sn0C-4uuoA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uuo CYTOSOLIC MALATE
DEHYDROGENASE

(Trichomonas
vaginalis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 LYS A 323
LEU A 136
ALA A 326
LEU A 332
ALA A 140
 None
 1.32A 1sn0A-4uuoA:
undetectable
1sn0C-4uuoA:
undetectable		 1sn0A-4uuoA:
17.16
1sn0C-4uuoA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynn PROTEASE DO

(Legionella
pneumophila) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		5 ALA A 101
LEU A 103
LEU A  88
GLU A  61
ALA A  86
 None
 1.03A 1sn0A-4ynnA:
undetectable
1sn0C-4ynnA:
undetectable		 1sn0A-4ynnA:
18.71
1sn0C-4ynnA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yu4 HEMOGLOBIN

(Helogale
parvula) 		PF00042
(Globin) 		5 LEU A 136
ALA A  82
LEU A  80
LYS A  61
ALA A  65
 None
None
None
HEM  A 201 (-2.6A)
HEM  A 201 (-3.6A)
 1.32A 1sn0A-4yu4A:
undetectable
1sn0C-4yu4A:
undetectable		 1sn0A-4yu4A:
23.18
1sn0C-4yu4A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwn DESIGNED HELICAL
REPEAT PROTEIN

(synthetic
construct) 		no annotation 5 LEU A  64
LYS A  81
LEU A  37
GLU A  77
ALA A  83
 None
None
PG4  A 302 ( 3.8A)
None
None
 1.49A 1sn0A-5cwnA:
undetectable
1sn0C-5cwnA:
undetectable		 1sn0A-5cwnA:
21.11
1sn0C-5cwnA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1a ICLR TRANSCRIPTION
FACTOR HOMOLOG

(Microbacterium
sp.) 		PF01614
(IclR)
PF09339
(HTH_IclR) 		5 LEU A  84
ALA A  88
LEU A 245
LEU A 217
ALA A 215
 None
 1.36A 1sn0A-5h1aA:
undetectable
1sn0C-5h1aA:
undetectable		 1sn0A-5h1aA:
17.12
1sn0C-5h1aA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n77 MAGNESIUM TRANSPORT
PROTEIN CORA

(Escherichia
coli) 		PF01544
(CorA) 		5 LEU A  23
LEU A  46
LYS A   1
LEU A  31
ALA A   4
 None
 1.41A 1sn0A-5n77A:
undetectable
1sn0C-5n77A:
undetectable		 1sn0A-5n77A:
18.50
1sn0C-5n77A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot4 INTERAPTIN

(Legionella
pneumophila) 		no annotation 5 LYS A 500
ALA A 502
LYS A 471
LEU A 467
GLU A 474
 None
 1.46A 1sn0A-5ot4A:
undetectable
1sn0C-5ot4A:
undetectable		 1sn0A-5ot4A:
19.47
1sn0C-5ot4A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v1w GLYCOSIDE HYDROLASE

(Bacillus
halodurans) 		PF03639
(Glyco_hydro_81) 		5 LEU A 373
ALA A 400
LEU A 411
LEU A 396
ALA A 376
 None
 1.40A 1sn0A-5v1wA:
undetectable
1sn0C-5v1wA:
undetectable		 1sn0A-5v1wA:
10.81
1sn0C-5v1wA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve8 KAP123

(Kluyveromyces
lactis) 		no annotation 5 LEU A 721
ALA A 724
LEU A 722
LEU A 685
GLU A 689
 None
 1.40A 1sn0A-5ve8A:
undetectable
1sn0C-5ve8A:
undetectable		 1sn0A-5ve8A:
7.53
1sn0C-5ve8A:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vyq UNCHARACTERIZED
PROTEIN

(Mycobacterium
tuberculosis) 		PF00551
(Formyl_trans_N) 		5 ALA A 202
LEU A 200
LEU A 182
GLU A 180
ALA A 211
 None
 1.39A 1sn0A-5vyqA:
undetectable
1sn0C-5vyqA:
undetectable		 1sn0A-5vyqA:
20.48
1sn0C-5vyqA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wq6 MBP TAGGED HMNDA-PYD

(Homo sapiens) 		PF02758
(PYRIN)
PF13416
(SBP_bac_8) 		5 LEU A 300
ALA A 304
LEU A 263
LEU A 286
GLU A 289
 None
 1.44A 1sn0A-5wq6A:
undetectable
1sn0C-5wq6A:
undetectable		 1sn0A-5wq6A:
16.12
1sn0C-5wq6A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6an0 HISTIDINOL
DEHYDROGENASE

(Elizabethkingia
anophelis) 		PF00815
(Histidinol_dh) 		5 LEU A 288
LEU A 285
LEU A 252
GLU A 352
ALA A 256
 None
 1.42A 1sn0A-6an0A:
undetectable
1sn0C-6an0A:
undetectable		 1sn0A-6an0A:
14.83
1sn0C-6an0A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6emk TARGET OF RAPAMYCIN
COMPLEX SUBUNIT LST8

(Saccharomyces
cerevisiae) 		no annotation 5 LEU B 265
ALA B 257
LEU B 279
LEU B 214
ALA B 223
 None
 1.27A 1sn0A-6emkB:
undetectable
1sn0C-6emkB:
undetectable		 1sn0A-6emkB:
24.79
1sn0C-6emkB:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gng -

(-) 		no annotation 5 LEU A 420
ALA A 422
LEU A 336
MET A 429
ALA A 352
 None
 1.42A 1sn0A-6gngA:
undetectable
1sn0C-6gngA:
undetectable		 1sn0A-6gngA:
undetectable
1sn0C-6gngA:
undetectable