SIMILAR PATTERNS OF AMINO ACIDS FOR 1SBR_B_VIBB503

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a6d THERMOSOME (BETA
SUBUNIT)

(Thermoplasma
acidophilum) 		PF00118
(Cpn60_TCP1) 		4 SER B 505
ILE B 137
ILE B 503
THR B  97
 None
 0.99A 1sbrB-1a6dB:
undetectable		 1sbrB-1a6dB:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1feh PROTEIN (PERIPLASMIC
HYDROGENASE 1)

(Clostridium
pasteurianum) 		PF02256
(Fe_hyd_SSU)
PF02906
(Fe_hyd_lg_C)
PF12838
(Fer4_7)
PF13510
(Fer2_4) 		4 SER A 139
ILE A 198
ILE A 197
THR A 380
 None
 0.97A 1sbrB-1fehA:
0.0		 1sbrB-1fehA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g6o CAG-ALPHA

(Helicobacter
pylori) 		PF00437
(T2SSE) 		4 PHE A  84
ILE A  45
ILE A  48
THR A  32
 None
 0.92A 1sbrB-1g6oA:
0.2		 1sbrB-1g6oA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8k ARSENITE OXIDASE

(Alcaligenes
faecalis) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 PHE A 161
ILE A 499
THR A 511
THR A 453
 None
 0.96A 1sbrB-1g8kA:
0.0		 1sbrB-1g8kA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcg ULBP3 PROTEIN

(Homo sapiens) 		PF00129
(MHC_I) 		4 PHE C 128
SER C 122
ILE C  20
LYS C  98
 None
 0.84A 1sbrB-1kcgC:
0.0		 1sbrB-1kcgC:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m2v PROTEIN TRANSPORT
PROTEIN SEC24

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 PHE B 540
ILE B 336
ILE B 548
THR B 325
 None
 0.92A 1sbrB-1m2vB:
undetectable		 1sbrB-1m2vB:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m2v PROTEIN TRANSPORT
PROTEIN SEC24

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 PHE B 540
SER B 541
ILE B 336
THR B 325
 None
 0.84A 1sbrB-1m2vB:
undetectable		 1sbrB-1m2vB:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nba N-CARBAMOYLSARCOSINE
AMIDOHYDROLASE

(Arthrobacter
sp.) 		PF00857
(Isochorismatase) 		4 ILE A 129
ILE A 133
THR A 170
THR A 198
 None
 0.93A 1sbrB-1nbaA:
undetectable		 1sbrB-1nbaA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nuq FKSG76

(Homo sapiens) 		PF01467
(CTP_transf_like) 		4 ILE A 224
ILE A 227
LYS A 228
THR A 234
 None
 0.82A 1sbrB-1nuqA:
undetectable		 1sbrB-1nuqA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1od3 PUTATIVE XYLANASE

([Clostridium]
stercorarium) 		PF03422
(CBM_6) 		4 SER A 136
ILE A  54
ILE A  57
THR A  87
 None
 0.95A 1sbrB-1od3A:
0.0		 1sbrB-1od3A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ox4 IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
HISHF

(Saccharomyces
cerevisiae) 		PF00117
(GATase)
PF00977
(His_biosynth) 		4 PHE B 192
ILE B  21
ILE B 205
THR B 190
 None
 0.96A 1sbrB-1ox4B:
undetectable		 1sbrB-1ox4B:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pd1 PROTEIN TRANSPORT
PROTEIN SEC24

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 PHE A 540
ILE A 336
ILE A 548
THR A 325
 None
 0.83A 1sbrB-1pd1A:
undetectable		 1sbrB-1pd1A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pd1 PROTEIN TRANSPORT
PROTEIN SEC24

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 PHE A 540
SER A 541
ILE A 336
THR A 325
 None
 0.95A 1sbrB-1pd1A:
undetectable		 1sbrB-1pd1A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pz1 GENERAL STRESS
PROTEIN 69

(Bacillus
subtilis) 		PF00248
(Aldo_ket_red) 		4 SER A  36
ILE A  70
ILE A  40
THR A  20
 None
 0.99A 1sbrB-1pz1A:
undetectable		 1sbrB-1pz1A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzs SUPEROXIDE DISMUTASE
[CU-ZN]

(Mycobacterium
tuberculosis) 		PF00080
(Sod_Cu) 		4 SER A  87
ILE A 168
ILE A  48
THR A 107
 None
 0.99A 1sbrB-1pzsA:
undetectable		 1sbrB-1pzsA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rfe HYPOTHETICAL PROTEIN
RV2991

(Mycobacterium
tuberculosis) 		PF01243
(Putative_PNPOx) 		4 PHE A  89
SER A  88
ILE A   9
THR A 142
 None
 0.82A 1sbrB-1rfeA:
undetectable		 1sbrB-1rfeA:
22.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s7h YKOF

(Bacillus
subtilis) 		PF07615
(Ykof) 		7 PHE A  15
SER A  16
ILE A  25
ILE A  28
LYS A  29
THR A  44
THR A  49
 None
 0.84A 1sbrB-1s7hA:
33.9		 1sbrB-1s7hA:
99.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkb LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 PHE A 159
SER A 160
ILE A 526
THR A  83
 None
 0.89A 1sbrB-1wkbA:
undetectable		 1sbrB-1wkbA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkb LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 PHE A 159
SER A 160
ILE A 526
THR A 152
 None
 0.92A 1sbrB-1wkbA:
undetectable		 1sbrB-1wkbA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 PHE A 159
SER A 160
THR A  83
THR A 152
 None
 0.98A 1sbrB-1wz2A:
undetectable		 1sbrB-1wz2A:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9s DNA POLYMERASE

(Escherichia
virus T7) 		PF00476
(DNA_pol_A) 		4 SER A 338
ILE A 383
ILE A 386
LYS A 387
 None
 0.90A 1sbrB-1x9sA:
3.5		 1sbrB-1x9sA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zfj INOSINE
MONOPHOSPHATE
DEHYDROGENASE

(Streptococcus
pyogenes) 		PF00478
(IMPDH)
PF00571
(CBS) 		4 ILE A 269
ILE A 266
LYS A 265
THR A 254
 None
 0.91A 1sbrB-1zfjA:
undetectable		 1sbrB-1zfjA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 SER A 661
ILE A 394
ILE A 707
THR A 646
 None
 1.00A 1sbrB-2b5mA:
undetectable		 1sbrB-2b5mA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ec6 MYOSIN REGULATORY
LIGHT CHAIN

(Placopecten
magellanicus) 		PF13405
(EF-hand_6) 		4 ILE B 112
ILE B 115
LYS B 116
THR B 134
 None
 0.87A 1sbrB-2ec6B:
undetectable		 1sbrB-2ec6B:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Staphylococcus
aureus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 PHE A  75
ILE A 188
ILE A 106
THR A  76
 None
 0.80A 1sbrB-2gqdA:
undetectable		 1sbrB-2gqdA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hv2 HYPOTHETICAL PROTEIN

(Enterococcus
faecalis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		4 PHE A  64
ILE A  78
THR A  44
THR A  62
 None
 0.96A 1sbrB-2hv2A:
undetectable		 1sbrB-2hv2A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iv0 ISOCITRATE
DEHYDROGENASE

(Archaeoglobus
fulgidus) 		PF00180
(Iso_dh) 		4 PHE A 401
ILE A 370
LYS A 371
THR A 348
 None
 0.95A 1sbrB-2iv0A:
undetectable		 1sbrB-2iv0A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jda YECBM32

(Yersinia
enterocolitica) 		PF00754
(F5_F8_type_C) 		4 SER A 126
ILE A 131
ILE A 128
THR A  93
 None
 0.95A 1sbrB-2jdaA:
undetectable		 1sbrB-2jdaA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l7e TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 14

(Saccharomyces
cerevisiae) 		PF03366
(YEATS) 		4 PHE A  51
ILE A  11
ILE A   9
THR A  68
 None
 0.98A 1sbrB-2l7eA:
undetectable		 1sbrB-2l7eA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l9j MATRIX PROTEIN 2-1

(Human
orthopneumovirus) 		PF06436
(Pneumovirus_M2) 		4 SER A 137
ILE A 111
ILE A 135
THR A 145
 None
 1.00A 1sbrB-2l9jA:
undetectable		 1sbrB-2l9jA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mq9 EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1

(Homo sapiens) 		PF03463
(eRF1_1) 		4 ILE A  14
ILE A  17
LYS A  18
THR A 133
 None
 0.92A 1sbrB-2mq9A:
undetectable		 1sbrB-2mq9A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mqb PROBABLE
BETA-LACTAMASE

(Staphylococcus
aureus) 		PF16229
(DUF4888) 		4 SER A  17
ILE A 146
ILE A  23
THR A  93
 None
 0.89A 1sbrB-2mqbA:
undetectable		 1sbrB-2mqbA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz9 BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		4 SER A1027
ILE A 983
ILE A1029
THR A1020
 None
 0.82A 1sbrB-2nz9A:
undetectable		 1sbrB-2nz9A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgq PROTEIN TM_1862

(Thermotoga
maritima) 		PF04055
(Radical_SAM) 		4 SER A 196
ILE A 238
ILE A 237
THR A 194
 None
 0.91A 1sbrB-2qgqA:
undetectable		 1sbrB-2qgqA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qu8 PUTATIVE NUCLEOLAR
GTP-BINDING PROTEIN
1

(Plasmodium
falciparum) 		PF06858
(NOG1) 		4 PHE A 184
SER A 183
ILE A 130
ILE A 116
 None
 0.95A 1sbrB-2qu8A:
undetectable		 1sbrB-2qu8A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcc RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
SUBUNIT BETA

(Bacillus
halodurans) 		PF00268
(Ribonuc_red_sm) 		4 SER A 124
ILE A  80
ILE A  81
THR A 208
 None
 0.88A 1sbrB-2rccA:
undetectable		 1sbrB-2rccA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhl N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE

(Bacillus
subtilis) 		PF01979
(Amidohydro_1) 		4 SER A 282
ILE A 277
ILE A 279
THR A  98
 None
 0.92A 1sbrB-2vhlA:
undetectable		 1sbrB-2vhlA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w01 ADENYLATE CYCLASE

(Synechocystis
sp. PCC 6803) 		PF00211
(Guanylate_cyc) 		4 ILE A 583
ILE A 585
THR A 443
THR A 545
 None
 0.91A 1sbrB-2w01A:
3.9		 1sbrB-2w01A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x40 BETA-GLUCOSIDASE

(Thermotoga
neapolitana) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 SER A 483
ILE A 452
ILE A 450
THR A 481
 None
 1.00A 1sbrB-2x40A:
undetectable		 1sbrB-2x40A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xk9 CHECKPOINT KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 251
ILE A 299
LYS A 249
THR A 367
 XK9  A1511 (-4.9A)
XK9  A1511 ( 4.9A)
XK9  A1511 (-4.2A)
XK9  A1511 (-3.7A)
 0.95A 1sbrB-2xk9A:
undetectable		 1sbrB-2xk9A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ycb CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR

(Methanothermobacter
thermautotrophicus) 		PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		4 PHE A  95
ILE A  83
ILE A  80
LYS A  79
 None
 0.96A 1sbrB-2ycbA:
undetectable		 1sbrB-2ycbA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z4t BETA-GALACTOSIDE
ALPHA-2,6-SIALYLTRAN
SFERASE

(Photobacterium
sp. JT-ISH-224) 		PF11477
(PM0188) 		4 PHE A 334
ILE A 425
ILE A 429
THR A 437
 None
 0.98A 1sbrB-2z4tA:
undetectable		 1sbrB-2z4tA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyg 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING

(Klebsiella
pneumoniae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 SER A 278
ILE A 189
ILE A 280
THR A 420
 None
 0.98A 1sbrB-2zygA:
undetectable		 1sbrB-2zygA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cnb DNA-BINDING RESPONSE
REGULATOR, MERR
FAMILY

(Colwellia
psychrerythraea) 		PF00072
(Response_reg) 		4 PHE A  66
SER A  67
ILE A 133
ILE A 142
 None
 0.97A 1sbrB-3cnbA:
undetectable		 1sbrB-3cnbA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csk PROBABLE
DIPEPTIDYL-PEPTIDASE
3

(Saccharomyces
cerevisiae) 		PF03571
(Peptidase_M49) 		4 PHE A 526
ILE A 536
ILE A 533
LYS A 532
 None
 0.95A 1sbrB-3cskA:
undetectable		 1sbrB-3cskA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cuq VACUOLAR-SORTING
PROTEIN SNF8

(Homo sapiens) 		PF04157
(EAP30) 		4 SER A 171
ILE A 145
ILE A 148
LYS A 149
 None
 0.97A 1sbrB-3cuqA:
undetectable		 1sbrB-3cuqA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epc PROTEIN VP1

(Enterovirus C) 		PF00073
(Rhv) 		4 SER 1 255
ILE 1 157
ILE 1 257
THR 1 139
 None
 0.96A 1sbrB-3epc1:
undetectable		 1sbrB-3epc1:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR

(Escherichia
coli;
Homo sapiens) 		PF02793
(HRM)
PF13416
(SBP_bac_8) 		4 SER A-230
ILE A-109
ILE A-228
THR A -99
 None
 1.00A 1sbrB-3l2jA:
undetectable		 1sbrB-3l2jA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzy RNA POLYMERASE
SIGMA-H FACTOR

(Fusobacterium
nucleatum) 		PF04542
(Sigma70_r2) 		4 PHE A 145
SER A 146
ILE A 185
ILE A 188
 None
 0.79A 1sbrB-3mzyA:
undetectable		 1sbrB-3mzyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE

(Klebsiella
pneumoniae) 		PF00266
(Aminotran_5) 		4 PHE A  99
ILE A  80
ILE A  77
THR A 176
 LLP  A 200 ( 3.7A)
None
None
LLP  A 200 ( 3.3A)
 0.92A 1sbrB-3nnkA:
2.5		 1sbrB-3nnkA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nv9 MALIC ENZYME

(Entamoeba
histolytica) 		PF00390
(malic)
PF03949
(Malic_M) 		4 PHE A  92
ILE A 137
ILE A 135
THR A 161
 None
 0.99A 1sbrB-3nv9A:
undetectable		 1sbrB-3nv9A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o04 BETA-KETO-ACYL
CARRIER PROTEIN
SYNTHASE II

(Listeria
monocytogenes) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 PHE A  74
ILE A 187
ILE A 105
THR A  75
 None
 0.78A 1sbrB-3o04A:
undetectable		 1sbrB-3o04A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r5g CYAB

(Pseudomonas
aeruginosa) 		PF00211
(Guanylate_cyc) 		4 ILE A 372
ILE A 374
THR A 229
THR A 334
 None
 0.86A 1sbrB-3r5gA:
3.9		 1sbrB-3r5gA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rd7 ACYL-COA
THIOESTERASE

(Mycobacterium
avium) 		PF13622
(4HBT_3) 		4 PHE A 247
SER A 248
THR A 274
THR A 259
 None
 0.78A 1sbrB-3rd7A:
undetectable		 1sbrB-3rd7A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ros NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Lactobacillus
acidophilus) 		PF00171
(Aldedh) 		4 SER A 391
ILE A 397
LYS A 401
THR A 412
 None
 0.95A 1sbrB-3rosA:
undetectable		 1sbrB-3rosA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rsj BONT/F

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 SER A1021
ILE A 977
ILE A1023
THR A1014
 None
 0.99A 1sbrB-3rsjA:
undetectable		 1sbrB-3rsjA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 PHE A 220
SER A 210
ILE A  60
THR A 218
 None
 0.89A 1sbrB-3szeA:
undetectable		 1sbrB-3szeA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czb NA(+)/H(+)
ANTIPORTER 1

(Methanocaldococcus
jannaschii) 		PF00999
(Na_H_Exchanger) 		4 PHE A 124
ILE A  32
ILE A 394
THR A 128
 None
 0.86A 1sbrB-4czbA:
undetectable		 1sbrB-4czbA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d9i DIAMINOPROPIONATE
AMMONIA-LYASE

(Escherichia
coli) 		PF00291
(PALP) 		4 PHE A   4
SER A   5
ILE A  10
ILE A   8
 None
 1.00A 1sbrB-4d9iA:
undetectable		 1sbrB-4d9iA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hln STARCH SYNTHASE I

(Hordeum vulgare) 		PF00534
(Glycos_transf_1)
PF08323
(Glyco_transf_5) 		4 ILE A 434
ILE A 437
LYS A 438
THR A 468
 None
 0.87A 1sbrB-4hlnA:
undetectable		 1sbrB-4hlnA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l37 SILKWORM STORAGE
PROTEIN

(Bombyx mori) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 PHE A 293
SER A 394
ILE A  80
THR A 401
 None
 1.00A 1sbrB-4l37A:
undetectable		 1sbrB-4l37A:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l63 ECXA

(Escherichia
coli) 		PF16313
(DUF4953) 		5 PHE A 112
SER A 111
ILE A  47
THR A 125
THR A 135
 None
 0.95A 1sbrB-4l63A:
undetectable		 1sbrB-4l63A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l63 ECXA

(Escherichia
coli) 		PF16313
(DUF4953) 		4 SER A 111
ILE A  44
THR A 125
THR A 135
 None
 0.94A 1sbrB-4l63A:
undetectable		 1sbrB-4l63A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mki ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA2

(Caldanaerobacter
subterraneus) 		no annotation 4 PHE B  35
ILE B 129
ILE B 189
THR B 197
 None
None
LMT  B 302 ( 4.6A)
None
 0.94A 1sbrB-4mkiB:
undetectable		 1sbrB-4mkiB:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT

(Escherichia
coli;
Mus musculus) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8) 		4 SER A 116
ILE A 237
ILE A 118
THR A 247
 None
 0.98A 1sbrB-4nufA:
undetectable		 1sbrB-4nufA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qre METHIONYL-TRNA
SYNTHETASE

(Staphylococcus
aureus) 		PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		4 ILE A  76
ILE A  79
LYS A  80
THR A  48
 None
 0.92A 1sbrB-4qreA:
undetectable		 1sbrB-4qreA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvu UNCHARACTERIZED
PROTEIN

(Bacillus cereus) 		PF16285
(DUF4931) 		4 PHE A  87
SER A  88
ILE A 126
ILE A 125
 None
 0.80A 1sbrB-4qvuA:
2.9		 1sbrB-4qvuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhc ALPHA-L-RHAMNOSIDASE

(Klebsiella
oxytoca) 		PF17389
(Bac_rhamnosid6H) 		4 PHE A 484
ILE A 466
ILE A 469
LYS A 470
 None
 0.98A 1sbrB-4xhcA:
undetectable		 1sbrB-4xhcA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xpm PROTEIN MEH1
UNCHARACTERIZED
PROTEIN YCR075W-A

(Saccharomyces
cerevisiae) 		PF11503
(DUF3215)
no annotation 		4 ILE A 168
ILE A 164
THR B  25
THR B  12
 None
 0.99A 1sbrB-4xpmA:
undetectable		 1sbrB-4xpmA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfa BONE
SIALOPROTEIN-BINDING
PROTEIN

(Staphylococcus
aureus) 		PF10425
(SdrG_C_C) 		4 ILE A 177
ILE A 159
THR A 189
THR A 297
 None
 0.82A 1sbrB-5cfaA:
2.1		 1sbrB-5cfaA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e16 CGMP-DEPENDENT
PROTEIN KINASE

(Plasmodium
falciparum) 		PF00027
(cNMP_binding) 		4 PHE A  95
ILE A  46
ILE A  49
LYS A  50
 None
 0.80A 1sbrB-5e16A:
undetectable		 1sbrB-5e16A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ekq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMC
OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAME

(Escherichia
coli) 		PF04355
(SmpA_OmlA)
PF06804
(Lipoprotein_18) 		4 PHE E  74
SER E  65
ILE C  57
THR E  72
 None
 0.74A 1sbrB-5ekqE:
undetectable		 1sbrB-5ekqE:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gai TAIL FIBER PROTEIN

(Salmonella
virus P22) 		no annotation 4 SER Y 462
ILE Y 476
ILE Y 478
THR Y 516
 None
 0.99A 1sbrB-5gaiY:
undetectable		 1sbrB-5gaiY:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gpp MALTOSE-BINDING
PERIPLASMIC
PROTEIN,APOPTOSIS-AS
SOCIATED SPECK-LIKE
PROTEIN CONTAINING A
CARD

(Danio rerio;
Escherichia
coli) 		PF02758
(PYRIN)
PF13416
(SBP_bac_8) 		4 SER A 115
ILE A 236
ILE A 117
THR A 246
 None
 0.95A 1sbrB-5gppA:
undetectable		 1sbrB-5gppA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gxv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,PIGG

(Escherichia
coli;
Serratia) 		PF13416
(SBP_bac_8) 		4 SER A 116
ILE A 237
ILE A 118
THR A 247
 None
 0.93A 1sbrB-5gxvA:
undetectable		 1sbrB-5gxvA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hra ASPARTATE/GLUTAMATE
RACEMASE

(Escherichia
coli) 		PF01177
(Asp_Glu_race) 		4 PHE A  45
ILE A 157
ILE A 161
THR A  85
 None
None
None
DAS  A 301 (-3.7A)
 1.00A 1sbrB-5hraA:
undetectable		 1sbrB-5hraA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		4 SER A 481
ILE A 602
ILE A 483
THR A 612
 None
 1.00A 1sbrB-5hzvA:
undetectable		 1sbrB-5hzvA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ic7 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 ILE A 501
ILE A 526
LYS A 524
THR A 451
 None
 0.98A 1sbrB-5ic7A:
undetectable		 1sbrB-5ic7A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j90 RAGB/SUSD DOMAIN
PROTEIN

(Flavobacterium
johnsoniae) 		PF12741
(SusD-like) 		4 PHE A  88
ILE A 336
ILE A 283
THR A  86
 None
 0.93A 1sbrB-5j90A:
undetectable		 1sbrB-5j90A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp0 BETA-GLUCOSIDASE
BOGH3B

(Bacteroides
ovatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 ILE A 111
ILE A 176
THR A 139
THR A 136
 None
 1.00A 1sbrB-5jp0A:
undetectable		 1sbrB-5jp0A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ld5 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Atopobium
vaginae) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 SER A 248
ILE A 234
THR A 260
THR A 193
 None
 0.83A 1sbrB-5ld5A:
undetectable		 1sbrB-5ld5A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ly3 ACTIN/ACTIN FAMILY
PROTEIN

(Pyrobaculum
calidifontis) 		PF00022
(Actin) 		4 PHE A 356
SER A 352
ILE A 192
ILE A 179
 None
 0.98A 1sbrB-5ly3A:
undetectable		 1sbrB-5ly3A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5moy BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 SER A1027
ILE A 983
ILE A1029
THR A1020
 None
 0.93A 1sbrB-5moyA:
undetectable		 1sbrB-5moyA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o98 ALCOHOL
DEHYDROGENASE 1

(Catharanthus
roseus) 		no annotation 4 SER A  30
ILE A  90
ILE A  33
LYS A   9
 None
 1.00A 1sbrB-5o98A:
undetectable		 1sbrB-5o98A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opq 3,6-ANHYDRO-D-GALACT
OSIDASE

(Zobellia
galactanivorans) 		no annotation 4 PHE A 578
ILE A 368
ILE A 608
THR A 592
 None
 0.76A 1sbrB-5opqA:
undetectable		 1sbrB-5opqA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpc BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 SER A1027
ILE A 983
ILE A1029
THR A1020
 None
 0.81A 1sbrB-5tpcA:
undetectable		 1sbrB-5tpcA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5upy INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Listeria
monocytogenes) 		PF00478
(IMPDH) 		4 ILE A 267
ILE A 264
LYS A 263
THR A 252
 None
 0.92A 1sbrB-5upyA:
undetectable		 1sbrB-5upyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wl3 ENGINEERED CHALCONE
ISOMERASE ANCR2

(unidentified) 		no annotation 4 PHE A 162
ILE A  96
ILE A  95
LYS A 144
 None
 0.93A 1sbrB-5wl3A:
undetectable		 1sbrB-5wl3A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu7 UNCHARACTERIZED
PROTEIN

(Pyrococcus
horikoshii) 		PF03065
(Glyco_hydro_57)
PF09210
(DUF1957) 		4 PHE A  60
SER A  59
THR A 356
THR A  11
 None
 0.91A 1sbrB-5wu7A:
undetectable		 1sbrB-5wu7A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wut ULAM111

(Flavobacterium
sp.) 		no annotation 4 PHE A  80
ILE A 228
ILE A 231
THR A  74
 None
 0.72A 1sbrB-5wutA:
undetectable		 1sbrB-5wutA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y2w RUBISCO OPERON
TRANSCRIPTIONAL
REGULATOR

(Synechocystis
sp. PCC 6803) 		no annotation 4 SER A 224
ILE A 169
THR A 102
THR A 101
 None
None
PGA  A 401 (-2.7A)
PGA  A 401 (-2.8A)
 0.97A 1sbrB-5y2wA:
undetectable		 1sbrB-5y2wA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yf0 -

(-) 		no annotation 4 PHE A 403
ILE A 331
ILE A 328
THR A 311
 None
 0.94A 1sbrB-5yf0A:
undetectable		 1sbrB-5yf0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6br8 PROTEIN A6 HOMOLOG

(Fowlpox virus) 		no annotation 4 ILE A 143
ILE A 140
LYS A 139
THR A 170
 6OU  A 405 (-4.4A)
6OU  A 405 ( 4.5A)
None
6OU  A 405 (-4.3A)
 0.86A 1sbrB-6br8A:
undetectable		 1sbrB-6br8A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c2j RNAP2

(Escherichia
virus N4) 		no annotation 4 ILE B 266
ILE B 269
LYS B 270
THR B 320
 None
 0.98A 1sbrB-6c2jB:
undetectable		 1sbrB-6c2jB:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6egt GLYCOPROTEIN

(Rift Valley
fever
phlebovirus) 		no annotation 4 SER A1003
ILE A1071
THR A 984
THR A 989
 None
 0.90A 1sbrB-6egtA:
undetectable		 1sbrB-6egtA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6erc PEROXINECTIN A

(Dictyostelium
discoideum) 		no annotation 4 PHE A  46
SER A 313
ILE A 170
THR A 317
 None
None
None
HEM  A 604 (-3.3A)
 0.98A 1sbrB-6ercA:
undetectable		 1sbrB-6ercA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fej ALL4940 PROTEIN

(Nostoc sp. PCC
7120) 		no annotation 4 PHE A  43
ILE A  19
ILE A  24
THR A 123
 None
URE  A 201 (-3.6A)
None
None
 0.76A 1sbrB-6fejA:
undetectable		 1sbrB-6fejA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fht BACTERIOPHYTOCHROME,
ADENYLATE CYCLASE

(Deinococcus
radiodurans;
Synechocystis
sp. PCC 6803) 		no annotation 4 ILE A 684
ILE A 686
THR A 544
THR A 646
 None
 0.91A 1sbrB-6fhtA:
3.8		 1sbrB-6fhtA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Cyanidioschyzon
merolae) 		no annotation 4 PHE A 606
SER A 607
ILE A 745
ILE A 744
 None
 0.98A 1sbrB-6fosA:
undetectable		 1sbrB-6fosA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbn -

(-) 		no annotation 4 SER A 190
ILE A 181
ILE A 183
THR A 188
 None
 1.00A 1sbrB-6gbnA:
undetectable		 1sbrB-6gbnA:
undetectable