SIMILAR PATTERNS OF AMINO ACIDS FOR 1SBR_A_VIBA501_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d5t GUANINE NUCLEOTIDE
DISSOCIATION
INHIBITOR

(Bos taurus) 		PF00996
(GDI) 		4 PHE A 184
LEU A 189
ILE A 206
ILE A 209
 None
 0.92A 1sbrA-1d5tA:
undetectable		 1sbrA-1d5tA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl3 PROTEIN
(PHOSPHORIBOSYLANTRA
NILATE ISOMERASE)

(Thermotoga
maritima) 		PF00697
(PRAI) 		4 PHE A  17
SER A  18
ILE A 199
LYS A 200
 None
 0.84A 1sbrA-1dl3A:
undetectable		 1sbrA-1dl3A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k0f PERIPLASMIC
ZINC-BINDING PROTEIN
TROA

(Treponema
pallidum) 		PF01297
(ZnuA) 		4 PHE A 236
LEU A 242
ILE A 272
ILE A 245
 None
 0.95A 1sbrA-1k0fA:
undetectable		 1sbrA-1k0fA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k4z ADENYLYL
CYCLASE-ASSOCIATED
PROTEIN

(Saccharomyces
cerevisiae) 		PF08603
(CAP_C) 		4 SER A1434
LEU A1432
ILE A1393
ILE A1413
 None
 0.86A 1sbrA-1k4zA:
0.0		 1sbrA-1k4zA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m2v PROTEIN TRANSPORT
PROTEIN SEC24

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 PHE B 540
SER B 541
ILE B 336
THR B 325
 None
 0.90A 1sbrA-1m2vB:
0.0		 1sbrA-1m2vB:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nba N-CARBAMOYLSARCOSINE
AMIDOHYDROLASE

(Arthrobacter
sp.) 		PF00857
(Isochorismatase) 		4 ILE A 129
ILE A 133
THR A 170
THR A 198
 None
 0.91A 1sbrA-1nbaA:
0.0		 1sbrA-1nbaA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ox4 IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
HISHF

(Saccharomyces
cerevisiae) 		PF00117
(GATase)
PF00977
(His_biosynth) 		4 PHE B 192
ILE B  21
ILE B 205
THR B 190
 None
 0.97A 1sbrA-1ox4B:
undetectable		 1sbrA-1ox4B:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pd1 PROTEIN TRANSPORT
PROTEIN SEC24

(Saccharomyces
cerevisiae) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 PHE A 540
SER A 541
ILE A 336
THR A 325
 None
 0.96A 1sbrA-1pd1A:
0.0		 1sbrA-1pd1A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qon ACETYLCHOLINESTERASE

(Drosophila
melanogaster) 		PF00135
(COesterase) 		4 PHE A 330
SER A 329
LEU A 328
ILE A 327
 I40  A 997 ( 4.1A)
None
None
None
 0.87A 1sbrA-1qonA:
0.0		 1sbrA-1qonA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4p SHIGA-LIKE TOXIN
TYPE II A SUBUNIT

(Escherichia
coli) 		PF00161
(RIP) 		4 SER A  39
LEU A  28
ILE A 228
ILE A  31
 None
 0.96A 1sbrA-1r4pA:
undetectable		 1sbrA-1r4pA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1reg T4 REGA

(Escherichia
virus T4) 		PF01818
(Translat_reg) 		4 PHE X  12
ILE X  86
ILE X   4
LYS X   1
 None
 0.86A 1sbrA-1regX:
undetectable		 1sbrA-1regX:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rfe HYPOTHETICAL PROTEIN
RV2991

(Mycobacterium
tuberculosis) 		PF01243
(Putative_PNPOx) 		4 PHE A  89
SER A  88
ILE A   9
THR A 142
 None
 0.77A 1sbrA-1rfeA:
undetectable		 1sbrA-1rfeA:
22.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1s7h YKOF

(Bacillus
subtilis) 		PF07615
(Ykof) 		8 PHE A  15
SER A  16
LEU A  17
ILE A  25
ILE A  28
LYS A  29
THR A  44
THR A  49
 None
 0.46A 1sbrA-1s7hA:
33.9		 1sbrA-1s7hA:
99.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1spx SHORT-CHAIN
REDUCTASE FAMILY
MEMBER (5L265)

(Caenorhabditis
elegans) 		PF13561
(adh_short_C2) 		4 LEU A 136
ILE A 181
ILE A 185
THR A 129
 None
 0.95A 1sbrA-1spxA:
undetectable		 1sbrA-1spxA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ufh YYCN PROTEIN

(Bacillus
subtilis) 		PF00583
(Acetyltransf_1) 		4 PHE A  13
LEU A  62
ILE A  91
THR A  20
 None
 0.85A 1sbrA-1ufhA:
undetectable		 1sbrA-1ufhA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xt0 GUANINE NUCLEOTIDE
EXCHANGE PROTEIN

(Legionella
pneumophila) 		PF01369
(Sec7) 		4 PHE B  46
ILE B  30
ILE B  27
LYS B  26
 None
 0.89A 1sbrA-1xt0B:
undetectable		 1sbrA-1xt0B:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2as5 FORKHEAD BOX PROTEIN
P2

(Homo sapiens) 		PF00250
(Forkhead) 		4 PHE F 538
LEU F 512
ILE F 517
THR F 537
 None
 0.86A 1sbrA-2as5F:
undetectable		 1sbrA-2as5F:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3l GLUCAN
1,4-ALPHA-MALTOHEXAO
SIDASE

(Bacillus sp.
707) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 PHE A 313
LEU A 405
ILE A 410
ILE A 411
 None
 0.92A 1sbrA-2d3lA:
undetectable		 1sbrA-2d3lA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d9q GRANULOCYTE
COLONY-STIMULATING
FACTOR RECEPTOR

(Homo sapiens) 		PF06328
(Lep_receptor_Ig) 		4 LEU B  80
ILE B  24
ILE B  25
LYS B  26
 None
 0.86A 1sbrA-2d9qB:
undetectable		 1sbrA-2d9qB:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ds2 SWEET PROTEIN
MABINLIN-2 CHAIN B

(Capparis
masaikai) 		PF00234
(Tryp_alpha_amyl) 		4 PHE B  49
LEU B  45
ILE B  38
ILE B  39
 None
 0.77A 1sbrA-2ds2B:
undetectable		 1sbrA-2ds2B:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqd 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Staphylococcus
aureus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 PHE A  75
ILE A 188
ILE A 106
THR A  76
 None
 0.82A 1sbrA-2gqdA:
undetectable		 1sbrA-2gqdA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gs8 MEVALONATE
PYROPHOSPHATE
DECARBOXYLASE

(Streptococcus
pyogenes) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 ILE A  79
ILE A  75
THR A  46
THR A  94
 None
 0.71A 1sbrA-2gs8A:
undetectable		 1sbrA-2gs8A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h8h PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC

(Homo sapiens) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		4 PHE A 212
SER A 222
LEU A 223
ILE A 143
 None
 0.94A 1sbrA-2h8hA:
undetectable		 1sbrA-2h8hA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix8 ELONGATION FACTOR 3A

(Saccharomyces
cerevisiae) 		PF00005
(ABC_tran) 		4 PHE A1435
SER A1436
LEU A1437
THR A1448
 None
 0.66A 1sbrA-2ix8A:
undetectable		 1sbrA-2ix8A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o6i HD DOMAIN PROTEIN

(Enterococcus
faecalis) 		PF01966
(HD) 		4 PHE A  64
SER A  65
LEU A  68
ILE A  24
 None
 0.90A 1sbrA-2o6iA:
undetectable		 1sbrA-2o6iA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1g PUTATIVE XYLANASE

(Bacteroides
fragilis) 		PF07313
(DUF1460) 		4 SER A  28
LEU A  27
ILE A 194
ILE A 211
 None
 0.95A 1sbrA-2p1gA:
undetectable		 1sbrA-2p1gA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgq PROTEIN TM_1862

(Thermotoga
maritima) 		PF04055
(Radical_SAM) 		4 SER A 196
ILE A 238
ILE A 237
THR A 194
 None
 0.91A 1sbrA-2qgqA:
undetectable		 1sbrA-2qgqA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhl N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE

(Bacillus
subtilis) 		PF01979
(Amidohydro_1) 		4 SER A 282
ILE A 277
ILE A 279
THR A  98
 None
 0.93A 1sbrA-2vhlA:
undetectable		 1sbrA-2vhlA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmf BETA-MANNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2) 		4 PHE A 552
SER A 554
LEU A 643
ILE A 394
 None
 0.97A 1sbrA-2vmfA:
undetectable		 1sbrA-2vmfA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w01 ADENYLATE CYCLASE

(Synechocystis
sp. PCC 6803) 		PF00211
(Guanylate_cyc) 		4 ILE A 583
ILE A 585
THR A 443
THR A 545
 None
 0.90A 1sbrA-2w01A:
3.4		 1sbrA-2w01A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w20 SIALIDASE A

(Streptococcus
pneumoniae) 		PF13088
(BNR_2) 		4 SER A 754
LEU A 755
ILE A 701
THR A 649
 None
 0.73A 1sbrA-2w20A:
undetectable		 1sbrA-2w20A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wn4 ADP-RIBOSYLTRANSFERA
SE ENZYMATIC
COMPONENT

(Clostridioides
difficile) 		PF03496
(ADPrib_exo_Tox) 		4 PHE A 396
LEU A 418
ILE A 367
THR A 346
 None
 0.93A 1sbrA-2wn4A:
undetectable		 1sbrA-2wn4A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zki 199AA LONG
HYPOTHETICAL TRP
REPRESSOR BINDING
PROTEIN

(Sulfurisphaera
tokodaii) 		PF03358
(FMN_red) 		4 ILE A 148
ILE A 179
LYS A 178
THR A 156
 None
None
SO4  A 503 ( 3.4A)
None
 0.93A 1sbrA-2zkiA:
undetectable		 1sbrA-2zkiA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ajb PEROXISOMAL
BIOGENESIS FACTOR 3

(Homo sapiens) 		PF04882
(Peroxin-3) 		4 SER A 199
LEU A 200
ILE A 328
ILE A 325
 None
 0.90A 1sbrA-3ajbA:
undetectable		 1sbrA-3ajbA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ble CITRAMALATE SYNTHASE
FROM LEPTOSPIRA
INTERROGANS

(Leptospira
interrogans) 		PF00682
(HMGL-like) 		4 PHE A 175
ILE A 135
ILE A 141
LYS A 140
 None
 0.95A 1sbrA-3bleA:
undetectable		 1sbrA-3bleA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddl XANTHORHODOPSIN

(Salinibacter
ruber) 		PF01036
(Bac_rhodopsin) 		4 SER A  14
LEU A  15
ILE A 225
THR A   9
 None
 0.96A 1sbrA-3ddlA:
undetectable		 1sbrA-3ddlA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ezy DEHYDROGENASE

(Thermotoga
maritima) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 SER A   0
LEU A   1
ILE A 291
LYS A 292
 None
 0.87A 1sbrA-3ezyA:
undetectable		 1sbrA-3ezyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6a HYDROLASE, NUDIX
FAMILY

(Clostridium
perfringens) 		PF00293
(NUDIX) 		4 LEU A  31
ILE A  46
LYS A  50
THR A 105
 None
 0.89A 1sbrA-3f6aA:
undetectable		 1sbrA-3f6aA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gkx PUTATIVE ARSC FAMILY
RELATED PROTEIN

(Bacteroides
fragilis) 		PF03960
(ArsC) 		4 PHE A 103
LEU A 105
THR A   3
THR A 100
 None
 0.86A 1sbrA-3gkxA:
undetectable		 1sbrA-3gkxA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		4 SER X 806
LEU X 805
LYS X 801
THR X 819
 None
 0.92A 1sbrA-3jb9X:
undetectable		 1sbrA-3jb9X:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kf3 INVERTASE

(Schwanniomyces
occidentalis) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 PHE A 153
SER A 154
LEU A 155
THR A 162
 None
 0.87A 1sbrA-3kf3A:
undetectable		 1sbrA-3kf3A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lqn CBS DOMAIN PROTEIN

(Bacillus
anthracis) 		PF00571
(CBS) 		4 PHE A 103
LEU A  17
ILE A 128
THR A 110
 None
 0.95A 1sbrA-3lqnA:
undetectable		 1sbrA-3lqnA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mpn TRANSPORTER

(Aquifex
aeolicus) 		PF00209
(SNF) 		4 LEU A  84
ILE A 421
ILE A 422
THR A  77
 None
 0.96A 1sbrA-3mpnA:
undetectable		 1sbrA-3mpnA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzy RNA POLYMERASE
SIGMA-H FACTOR

(Fusobacterium
nucleatum) 		PF04542
(Sigma70_r2) 		4 PHE A 145
SER A 146
ILE A 185
ILE A 188
 None
 0.76A 1sbrA-3mzyA:
undetectable		 1sbrA-3mzyA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE

(Klebsiella
pneumoniae) 		PF00266
(Aminotran_5) 		4 PHE A  99
ILE A  80
ILE A  77
THR A 176
 LLP  A 200 ( 3.7A)
None
None
LLP  A 200 ( 3.3A)
 0.94A 1sbrA-3nnkA:
undetectable		 1sbrA-3nnkA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o04 BETA-KETO-ACYL
CARRIER PROTEIN
SYNTHASE II

(Listeria
monocytogenes) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 PHE A  74
ILE A 187
ILE A 105
THR A  75
 None
 0.82A 1sbrA-3o04A:
undetectable		 1sbrA-3o04A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9t CHOLINE
DEHYDROGENASE AND
RELATED
FLAVOPROTEINS

(Aspergillus
oryzae) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 PHE A 213
SER A 212
LEU A 214
ILE A 158
 None
 0.94A 1sbrA-3q9tA:
undetectable		 1sbrA-3q9tA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r5g CYAB

(Pseudomonas
aeruginosa) 		PF00211
(Guanylate_cyc) 		4 ILE A 372
ILE A 374
THR A 229
THR A 334
 None
 0.86A 1sbrA-3r5gA:
3.6		 1sbrA-3r5gA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rd7 ACYL-COA
THIOESTERASE

(Mycobacterium
avium) 		PF13622
(4HBT_3) 		4 PHE A 247
SER A 248
THR A 274
THR A 259
 None
 0.75A 1sbrA-3rd7A:
undetectable		 1sbrA-3rd7A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rze HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA

(Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 PHE A 116
LEU A 154
ILE A 160
THR A 112
 None
None
None
D7V  A1201 ( 4.0A)
 0.86A 1sbrA-3rzeA:
undetectable		 1sbrA-3rzeA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdq ALPHA-BISABOLENE
SYNTHASE

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 LEU A 132
ILE A 156
ILE A 159
LYS A 160
 None
 0.57A 1sbrA-3sdqA:
undetectable		 1sbrA-3sdqA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 PHE A 220
SER A 210
ILE A  60
THR A 218
 None
 0.85A 1sbrA-3szeA:
undetectable		 1sbrA-3szeA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti2 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Vibrio cholerae) 		PF00275
(EPSP_synthase) 		4 SER A  21
LEU A  45
ILE A  50
THR A  97
 None
None
None
CL  A 245 ( 4.4A)
 0.98A 1sbrA-3ti2A:
undetectable		 1sbrA-3ti2A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3va6 TWO-COMPONENT SYSTEM
SENSOR HISTIDINE
KINASE

(Bacteroides
thetaiotaomicron) 		PF07494
(Reg_prop)
PF07495
(Y_Y_Y) 		4 SER A 222
LEU A 223
ILE A 179
THR A 134
 None
 0.88A 1sbrA-3va6A:
undetectable		 1sbrA-3va6A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0d ELASTASE INHIBITOR
AFUEI

(Aspergillus
fumigatus) 		PF11720
(Inhibitor_I78) 		4 LEU A  16
ILE A  63
ILE A  62
THR A  22
 None
 0.96A 1sbrA-3w0dA:
undetectable		 1sbrA-3w0dA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zi5 RESTRICTION
ENDONUCLEASE

(Bacillus firmus) 		no annotation 4 SER A 325
LEU A 327
ILE A 301
THR A 321
 None
 0.89A 1sbrA-3zi5A:
undetectable		 1sbrA-3zi5A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyj LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 4C

(Homo sapiens) 		PF00560
(LRR_1)
PF07679
(I-set)
PF13306
(LRR_5)
PF13855
(LRR_8) 		4 PHE A 239
LEU A 248
ILE A 296
ILE A 272
 None
 0.88A 1sbrA-3zyjA:
undetectable		 1sbrA-3zyjA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxm ERPC

(Borreliella
burgdorferi) 		PF02471
(OspE) 		4 PHE A  73
SER A  74
LEU A  75
THR A  53
 None
 0.97A 1sbrA-4bxmA:
undetectable		 1sbrA-4bxmA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d9i DIAMINOPROPIONATE
AMMONIA-LYASE

(Escherichia
coli) 		PF00291
(PALP) 		4 PHE A   4
SER A   5
LEU A   6
ILE A 310
 None
 0.85A 1sbrA-4d9iA:
undetectable		 1sbrA-4d9iA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dpk MALONYL-COA/SUCCINYL
-COA REDUCTASE

(Sulfurisphaera
tokodaii) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 SER A 234
LEU A 235
ILE A 211
LYS A 212
 None
 0.84A 1sbrA-4dpkA:
undetectable		 1sbrA-4dpkA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eba MRNA
3'-END-PROCESSING
PROTEIN RNA14

(Kluyveromyces
lactis) 		PF05843
(Suf) 		4 PHE A 526
LEU A 522
ILE A 516
LYS A 515
 None
 0.84A 1sbrA-4ebaA:
undetectable		 1sbrA-4ebaA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fk7 PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX

(Bacillus cereus) 		PF03496
(ADPrib_exo_Tox) 		4 LEU A 337
ILE A 467
ILE A 411
THR A 388
 None
 0.97A 1sbrA-4fk7A:
undetectable		 1sbrA-4fk7A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g0b HYDROXYCINNAMOYL-COA
SHIKIMATE/QUINATE
HYDROXYCINNAMOYLTRAN
SFERASE

(Coffea
canephora) 		PF02458
(Transferase) 		4 PHE A 402
SER A 401
LEU A 400
THR A 370
 None
 0.89A 1sbrA-4g0bA:
undetectable		 1sbrA-4g0bA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ipa PUTATIVE CURVED
DNA-BINDING PROTEIN

(Chaetomium
thermophilum) 		PF00557
(Peptidase_M24) 		4 SER A  36
LEU A  38
ILE A  45
ILE A  48
 None
 0.80A 1sbrA-4ipaA:
undetectable		 1sbrA-4ipaA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ipa PUTATIVE CURVED
DNA-BINDING PROTEIN

(Chaetomium
thermophilum) 		PF00557
(Peptidase_M24) 		4 SER A  36
LEU A  38
ILE A  48
THR A  77
 None
 0.95A 1sbrA-4ipaA:
undetectable		 1sbrA-4ipaA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k11 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC

(Homo sapiens) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		4 PHE A 212
SER A 222
LEU A 223
ILE A 143
 None
 0.94A 1sbrA-4k11A:
undetectable		 1sbrA-4k11A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l63 ECXA

(Escherichia
coli) 		PF16313
(DUF4953) 		5 PHE A 112
SER A 111
ILE A  47
THR A 125
THR A 135
 None
 0.91A 1sbrA-4l63A:
undetectable		 1sbrA-4l63A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l63 ECXA

(Escherichia
coli) 		PF16313
(DUF4953) 		4 SER A 111
ILE A  44
THR A 125
THR A 135
 None
 0.94A 1sbrA-4l63A:
undetectable		 1sbrA-4l63A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lnq INTERFERON-ACTIVABLE
PROTEIN 202

(Mus musculus) 		PF02760
(HIN) 		4 LEU A 156
ILE A 197
ILE A 161
THR A 168
 None
 0.84A 1sbrA-4lnqA:
undetectable		 1sbrA-4lnqA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mbo SERINE-RICH REPEAT
ADHESION
GLYCOPROTEIN (SRR1)

(Streptococcus
agalactiae) 		PF10425
(SdrG_C_C) 		4 SER A 420
LEU A 422
ILE A 425
THR A 416
 None
 0.96A 1sbrA-4mboA:
undetectable		 1sbrA-4mboA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n78 CYTOPLASMIC
FMR1-INTERACTING
PROTEIN 1

(Homo sapiens) 		PF05994
(FragX_IP)
PF07159
(DUF1394) 		4 SER A 402
LEU A 401
ILE A 455
ILE A 458
 None
 0.87A 1sbrA-4n78A:
undetectable		 1sbrA-4n78A:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1e TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Escherichia
fergusonii) 		PF03480
(DctP) 		4 PHE A  99
LEU A 140
ILE A 241
ILE A 242
 None
 0.87A 1sbrA-4p1eA:
undetectable		 1sbrA-4p1eA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pgw UNCHARACTERIZED
PROTEIN YETJ

(Bacillus
subtilis) 		PF01027
(Bax1-I) 		4 PHE A 124
SER A 123
LEU A 122
LYS A 119
 None
 0.91A 1sbrA-4pgwA:
undetectable		 1sbrA-4pgwA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q3m MGS-M4

(unidentified) 		PF00248
(Aldo_ket_red) 		4 SER A 197
LEU A 196
ILE A 215
ILE A 212
 None
 0.97A 1sbrA-4q3mA:
undetectable		 1sbrA-4q3mA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvu UNCHARACTERIZED
PROTEIN

(Bacillus cereus) 		PF16285
(DUF4931) 		4 PHE A  87
SER A  88
ILE A 126
ILE A 125
 None
 0.78A 1sbrA-4qvuA:
2.6		 1sbrA-4qvuA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ryi INTEGRAL MEMBRANE
PROTEIN

(Bacillus cereus) 		PF03073
(TspO_MBR) 		4 PHE A 120
SER A 121
LEU A 124
ILE A  65
 None
 0.95A 1sbrA-4ryiA:
undetectable		 1sbrA-4ryiA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tps SPORULATION
INHIBITOR OF
REPLICATION PROTEIN
SIRA

(Bacillus
subtilis) 		PF10747
(SirA) 		4 LEU A   9
ILE A  58
ILE A  56
THR A   7
 None
 0.98A 1sbrA-4tpsA:
2.5		 1sbrA-4tpsA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8y CRISPR SYSTEM CMR
SUBUNIT CMR2

(Pyrococcus
furiosus) 		PF12469
(DUF3692) 		4 PHE A 325
LEU A 329
ILE A 483
LYS A 484
 None
 0.92A 1sbrA-4w8yA:
3.0		 1sbrA-4w8yA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5djw ALPHA-GLUCOSIDASE II

(Bacteroides
thetaiotaomicron) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF17137
(DUF5110) 		4 LEU A 490
ILE A 583
ILE A 489
THR A 596
 None
 0.95A 1sbrA-5djwA:
undetectable		 1sbrA-5djwA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ekq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMC
OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAME

(Escherichia
coli) 		PF04355
(SmpA_OmlA)
PF06804
(Lipoprotein_18) 		4 PHE E  74
SER E  65
ILE C  57
THR E  72
 None
 0.78A 1sbrA-5ekqE:
undetectable		 1sbrA-5ekqE:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqv BIFUNCTIONAL
2',3'-CYCLIC
NUCLEOTIDE
2'-PHOSPHODIESTERASE
/3'-NUCLEOTIDASE
PERIPLASMIC
PRECURSOR PROTEIN

(Yersinia pestis) 		PF00149
(Metallophos) 		4 PHE A 308
LEU A 227
ILE A 166
ILE A 182
 None
 0.94A 1sbrA-5eqvA:
undetectable		 1sbrA-5eqvA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzg GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A 153
SER A 152
ILE A 105
THR A  31
 None
 0.96A 1sbrA-5gzgA:
undetectable		 1sbrA-5gzgA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7w VENOM
5'-NUCLEOTIDASE

(Naja atra) 		no annotation 4 LEU A 108
ILE A  71
ILE A  68
THR A  35
 None
 0.83A 1sbrA-5h7wA:
undetectable		 1sbrA-5h7wA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 PHE B 360
LEU B 254
ILE B 222
ILE B 240
 None
 0.74A 1sbrA-5ip9B:
undetectable		 1sbrA-5ip9B:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j90 RAGB/SUSD DOMAIN
PROTEIN

(Flavobacterium
johnsoniae) 		PF12741
(SusD-like) 		4 PHE A  88
ILE A 336
ILE A 283
THR A  86
 None
 0.89A 1sbrA-5j90A:
undetectable		 1sbrA-5j90A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kjv HYDROXYCINNAMOYL
TRANSFERASE

(Plectranthus
scutellarioides) 		PF02458
(Transferase) 		4 PHE A 395
SER A 394
LEU A 393
THR A 363
 None
 0.87A 1sbrA-5kjvA:
undetectable		 1sbrA-5kjvA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqi PROTEIN TIMELESS
HOMOLOG,PROTEIN
TIMELESS HOMOLOG

(Homo sapiens) 		PF04821
(TIMELESS) 		4 PHE A 130
LEU A 133
ILE A 156
ILE A 159
 None
 0.87A 1sbrA-5mqiA:
undetectable		 1sbrA-5mqiA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nbq OUTER SURFACE
PROTEIN E

(Borreliella
burgdorferi) 		no annotation 4 PHE G  86
SER G  87
LEU G  88
THR G  74
 None
 0.91A 1sbrA-5nbqG:
undetectable		 1sbrA-5nbqG:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uiv BIFUNCTIONAL
THYMIDYLATE/URIDYLAT
E KINASE

(Candida
albicans) 		PF02223
(Thymidylate_kin) 		4 SER A  22
LEU A  24
ILE A  88
ILE A  89
 None
 0.84A 1sbrA-5uivA:
undetectable		 1sbrA-5uivA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wl3 ENGINEERED CHALCONE
ISOMERASE ANCR2

(unidentified) 		no annotation 4 PHE A 137
LEU A 142
ILE A  96
ILE A  95
 None
 0.98A 1sbrA-5wl3A:
undetectable		 1sbrA-5wl3A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu7 UNCHARACTERIZED
PROTEIN

(Pyrococcus
horikoshii) 		PF03065
(Glyco_hydro_57)
PF09210
(DUF1957) 		4 PHE A  60
SER A  59
THR A 356
THR A  11
 None
 0.89A 1sbrA-5wu7A:
undetectable		 1sbrA-5wu7A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wut ULAM111

(Flavobacterium
sp.) 		no annotation 4 PHE A  80
ILE A 228
ILE A 231
THR A  74
 None
 0.69A 1sbrA-5wutA:
undetectable		 1sbrA-5wutA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgc RAP1 GTPASE-GDP
DISSOCIATION
STIMULATOR 1

(Homo sapiens) 		PF00514
(Arm) 		4 SER A 244
LEU A 221
ILE A 224
THR A 242
 None
 0.93A 1sbrA-5xgcA:
undetectable		 1sbrA-5xgcA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6an7 TRANSPORT PERMEASE
PROTEIN

(Aquifex
aeolicus) 		no annotation 5 PHE D  74
SER D  75
LEU D  78
ILE D 171
ILE D 172
 None
 1.11A 1sbrA-6an7D:
undetectable		 1sbrA-6an7D:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c3p ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8

(Homo sapiens) 		no annotation 4 PHE E 432
LEU E 387
ILE E 395
ILE E 391
 None
 0.80A 1sbrA-6c3pE:
undetectable		 1sbrA-6c3pE:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cf8 LYTIC
TRANSGLYCOSYLASE

(Campylobacter
jejuni) 		no annotation 4 PHE A  60
SER A  31
LEU A  32
ILE A 394
 None
 0.80A 1sbrA-6cf8A:
0.9		 1sbrA-6cf8A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6egt GLYCOPROTEIN

(Rift Valley
fever
phlebovirus) 		no annotation 4 SER A1003
ILE A1071
THR A 984
THR A 989
 None
 0.87A 1sbrA-6egtA:
undetectable		 1sbrA-6egtA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fht BACTERIOPHYTOCHROME,
ADENYLATE CYCLASE

(Deinococcus
radiodurans;
Synechocystis
sp. PCC 6803) 		no annotation 4 ILE A 684
ILE A 686
THR A 544
THR A 646
 None
 0.90A 1sbrA-6fhtA:
3.3		 1sbrA-6fhtA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
ALPHA, CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 4 ILE C 116
ILE C 109
LYS C 114
THR C 242
 None
 0.85A 1sbrA-6fkhC:
undetectable		 1sbrA-6fkhC:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
ALPHA, CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 4 SER C 275
LEU C 277
ILE C  39
THR C 234
 None
 0.91A 1sbrA-6fkhC:
undetectable		 1sbrA-6fkhC:
19.00