SIMILAR PATTERNS OF AMINO ACIDS FOR 1S9P_D_DESD600_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3h | GUANOSINEPENTAPHOSPHATESYNTHETASE (Streptomycesantibioticus) |
PF00013(KH_1)PF01138(RNase_PH)PF03726(PNPase) | 5 | LEU A 268LEU A 271ALA A 274VAL A 298LEU A 328 | None | 1.07A | 1s9pD-1e3hA:undetectable | 1s9pD-1e3hA:14.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gju | MALTODEXTRINGLYCOSYLTRANSFERASE (Thermotogamaritima) |
PF00128(Alpha-amylase)PF09083(DUF1923) | 5 | LEU A 175LEU A 174TYR A 20LEU A 124ILE A 6 | None | 1.10A | 1s9pD-1gjuA:undetectable | 1s9pD-1gjuA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpm | GMP SYNTHETASE (Escherichiacoli) |
PF00117(GATase)PF00958(GMP_synt_C)PF02540(NAD_synthase) | 5 | LEU A 379LEU A 376LEU A 247LEU A 391ILE A 213 | None | 1.15A | 1s9pD-1gpmA:undetectable | 1s9pD-1gpmA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i5p | PESTICIDIAL CRYSTALPROTEIN CRY2AA (Bacillusthuringiensis) |
PF03944(Endotoxin_C)PF03945(Endotoxin_N)PF09131(Endotoxin_mid) | 5 | LEU A 173LEU A 176ALA A 180LEU A 120ILE A 166 | None | 1.02A | 1s9pD-1i5pA:2.2 | 1s9pD-1i5pA:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1im3 | CYTOMEGALOVIRUSPROTEIN US2 (Humanbetaherpesvirus5) |
PF05963(Cytomega_US3) | 5 | LEU D 131LEU D 120VAL D 89LEU D 102ILE D 129 | None | 1.15A | 1s9pD-1im3D:undetectable | 1s9pD-1im3D:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iz1 | LYSR-TYPE REGULATORYPROTEIN (Cupriavidusnecator) |
PF00126(HTH_1)PF03466(LysR_substrate) | 5 | LEU A 6ALA A 13LEU A 57LEU A 43ILE A 71 | None | 1.13A | 1s9pD-1iz1A:undetectable | 1s9pD-1iz1A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k38 | BETA-LACTAMASE OXA-2 (Salmonellaenterica) |
PF00905(Transpeptidase) | 5 | LEU A 75ALA A 82VAL A 119TYR A 120LEU A 191 | NoneNoneNoneKCX A 70 ( 3.7A)None | 1.04A | 1s9pD-1k38A:0.0 | 1s9pD-1k38A:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ks9 | 2-DEHYDROPANTOATE2-REDUCTASE (Escherichiacoli) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | LEU A 68MET A 1VAL A 159LEU A 152ILE A 93 | None | 1.08A | 1s9pD-1ks9A:undetectable | 1s9pD-1ks9A:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odo | PUTATIVE CYTOCHROMEP450 154A1 (Streptomycescoelicolor) |
PF00067(p450) | 5 | LEU A 24LEU A 8ALA A 7LEU A 393HIS A 291 | None | 1.11A | 1s9pD-1odoA:2.4 | 1s9pD-1odoA:20.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 346ALA A 350GLU A 353LEU A 387ARG A 394HIS A 524 | EST A 1 (-4.4A)EST A 1 ( 3.7A)EST A 1 (-2.8A)EST A 1 (-4.0A)EST A 1 (-3.7A)EST A 1 (-3.8A) | 0.39A | 1s9pD-1pcgA:29.4 | 1s9pD-1pcgA:36.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s5j | DNA POLYMERASE I (Sulfolobussolfataricus) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | LEU A 387LEU A 386LEU A 431VAL A 365LEU A 356 | None | 1.10A | 1s9pD-1s5jA:0.1 | 1s9pD-1s5jA:16.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sus | CAFFEOYL-COAO-METHYLTRANSFERASE (Medicago sativa) |
PF01596(Methyltransf_3) | 5 | LEU A 179LEU A 176LEU A 170LEU A 141ILE A 148 | None | 1.13A | 1s9pD-1susA:undetectable | 1s9pD-1susA:24.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1to3 | PUTATIVE ALDOLASEYIHT (Salmonellaenterica) |
PF01791(DeoC) | 5 | ALA A 244GLU A 243LEU A 208LEU A 198ILE A 177 | None | 1.09A | 1s9pD-1to3A:undetectable | 1s9pD-1to3A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1udd | TRANSCRIPTIONALREGULATOR (Pyrococcushorikoshii) |
PF03070(TENA_THI-4) | 5 | LEU A 130LEU A 133GLU A 204LEU A 75ILE A 181 | None | 0.88A | 1s9pD-1uddA:2.2 | 1s9pD-1uddA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vmi | PUTATIVE PHOSPHATEACETYLTRANSFERASE (Escherichiacoli) |
PF01515(PTA_PTB) | 5 | ALA A 31MET A 62LEU A 65VAL A 67HIS A 58 | None | 1.12A | 1s9pD-1vmiA:undetectable | 1s9pD-1vmiA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wzz | PROBABLEENDOGLUCANASE (Komagataeibacterxylinus) |
PF01270(Glyco_hydro_8) | 5 | LEU A 328LEU A 331ALA A 335GLU A 338ILE A 247 | None | 1.04A | 1s9pD-1wzzA:undetectable | 1s9pD-1wzzA:19.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xb7 | STEROID HORMONERECEPTOR ERR1 (Homo sapiens) |
PF00104(Hormone_recep) | 8 | LEU A 324GLU A 331MET A 362LEU A 365VAL A 369ARG A 372LEU A 401HIS A 494 | None | 0.46A | 1s9pD-1xb7A:30.3 | 1s9pD-1xb7A:58.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygu | LEUKOCYTE COMMONANTIGEN (Homo sapiens) |
PF00102(Y_phosphatase) | 5 | LEU A1157LEU A1160ALA A1164LEU A 897VAL A 895 | None | 0.80A | 1s9pD-1yguA:undetectable | 1s9pD-1yguA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cvt | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASELARGE CHAIN 1 (Saccharomycescerevisiae) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 5 | LEU A 470ALA A 474MET A 603LEU A 507VAL A 509 | None | 1.08A | 1s9pD-2cvtA:undetectable | 1s9pD-2cvtA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fek | LOW MOLECULAR WEIGHTPROTEIN-TYROSINE-PHOSPHATASE WZB (Escherichiacoli) |
PF01451(LMWPc) | 5 | LEU A 131ALA A 135LEU A 23VAL A 7LEU A 60 | None | 0.99A | 1s9pD-2fekA:undetectable | 1s9pD-2fekA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g85 | CHORISMATE SYNTHASE (Mycobacteriumtuberculosis) |
PF01264(Chorismate_synt) | 5 | LEU A 159LEU A 155ALA A 153LEU A 367ILE A 382 | None | 0.99A | 1s9pD-2g85A:undetectable | 1s9pD-2g85A:20.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gpv | ESTROGEN-RELATEDRECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 11 | LEU A 265LEU A 268ALA A 272GLU A 275MET A 306LEU A 309VAL A 313ARG A 316TYR A 326LEU A 345HIS A 434 | NoneOHT A 500 (-4.1A)OHT A 500 (-3.5A)OHT A 500 (-2.6A)OHT A 500 (-3.9A)OHT A 500 ( 4.0A)NoneOHT A 500 (-3.8A)OHT A 500 (-4.5A)OHT A 500 (-4.3A)OHT A 500 ( 4.7A) | 0.48A | 1s9pD-2gpvA:33.7 | 1s9pD-2gpvA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gpv | ESTROGEN-RELATEDRECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 11 | LEU A 265LEU A 268ALA A 272MET A 306LEU A 309VAL A 313ARG A 316TYR A 326LEU A 345HIS A 434ILE A 438 | NoneOHT A 500 (-4.1A)OHT A 500 (-3.5A)OHT A 500 (-3.9A)OHT A 500 ( 4.0A)NoneOHT A 500 (-3.8A)OHT A 500 (-4.5A)OHT A 500 (-4.3A)OHT A 500 ( 4.7A)None | 0.60A | 1s9pD-2gpvA:33.7 | 1s9pD-2gpvA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h3j | HYPOTHETICAL PROTEINPA4359 (Pseudomonasaeruginosa) |
PF04023(FeoA) | 5 | LEU A 27LEU A 32ALA A 36VAL A 52LEU A 66 | None | 1.08A | 1s9pD-2h3jA:undetectable | 1s9pD-2h3jA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i0k | OXIDOREDUCTASE (Brevibacteriumsterolicum) |
PF01565(FAD_binding_4)PF09129(Chol_subst-bind) | 5 | LEU A 222LEU A 225VAL A 157LEU A 175ILE A 168 | None | 1.08A | 1s9pD-2i0kA:undetectable | 1s9pD-2i0kA:16.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inc | TOLUENE, O-XYLENEMONOOXYGENASEOXYGENASE SUBUNIT (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox) | 6 | LEU B 113LEU B 121GLU B 189TYR B 125LEU B 249HIS B 109 | None | 1.41A | 1s9pD-2incB:undetectable | 1s9pD-2incB:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k9x | UNCHARACTERIZEDPROTEIN (Trypanosomabrucei) |
PF09138(Urm1) | 5 | LEU A 87ALA A 77GLU A 78LEU A 44ILE A 7 | None | 1.12A | 1s9pD-2k9xA:undetectable | 1s9pD-2k9xA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o7p | RIBOFLAVINBIOSYNTHESIS PROTEINRIBD (Escherichiacoli) |
PF00383(dCMP_cyt_deam_1)PF01872(RibD_C) | 5 | LEU A 72ALA A 131GLU A 132ARG A 143LEU A 112 | None | 1.14A | 1s9pD-2o7pA:undetectable | 1s9pD-2o7pA:20.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 346ALA A 350GLU A 353LEU A 387ARG A 394HIS A 524 | EST A 596 (-4.4A)EST A 596 ( 3.9A)EST A 596 (-2.7A)EST A 596 ( 4.2A)EST A 596 (-4.0A)EST A 596 (-4.2A) | 0.58A | 1s9pD-2ocfA:30.1 | 1s9pD-2ocfA:31.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q3y | ANCESTRAL CORTICIODRECEPTOR (unidentified) |
PF00104(Hormone_recep) | 5 | LEU A 29LEU A 32ALA A 36MET A 70ARG A 80 | 1CA A 247 ( 3.6A)1CA A 247 (-4.0A)1CA A 247 (-3.6A)1CA A 247 ( 3.8A)1CA A 247 (-3.8A) | 0.39A | 1s9pD-2q3yA:28.0 | 1s9pD-2q3yA:27.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w1v | NITRILASE HOMOLOG 2 (Mus musculus) |
PF00795(CN_hydrolase) | 5 | ALA A 242LEU A 210VAL A 239HIS A 148ILE A 190 | None | 1.14A | 1s9pD-2w1vA:undetectable | 1s9pD-2w1vA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wdw | PUTATIVE HEXOSEOXIDASE (Nonomuraeagerenzanensis) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | LEU A 179ALA A 416LEU A 502VAL A 505ILE A 160 | None | 0.85A | 1s9pD-2wdwA:undetectable | 1s9pD-2wdwA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3s | TAML (Streptomycessp. 307-9) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | LEU A 150ALA A 390LEU A 476VAL A 479ILE A 131 | None | 0.85A | 1s9pD-2y3sA:undetectable | 1s9pD-2y3sA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yzm | D-ALANINE--D-ALANINELIGASE (Thermusthermophilus) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 5 | LEU A 80ALA A 7LEU A 18VAL A 16ILE A 28 | None | 1.12A | 1s9pD-2yzmA:undetectable | 1s9pD-2yzmA:24.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a0f | XYLOGLUCANASE (Geotrichum sp.M128) |
no annotation | 5 | LEU A 641ALA A 587VAL A 606LEU A 621ILE A 650 | None | 1.13A | 1s9pD-3a0fA:undetectable | 1s9pD-3a0fA:13.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bbl | REGULATORY PROTEINOF LACI FAMILY (Chloroflexusaggregans) |
PF13377(Peripla_BP_3) | 5 | LEU A 179GLU A 218ARG A 246LEU A 277ILE A 280 | None | 1.00A | 1s9pD-3bblA:undetectable | 1s9pD-3bblA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bpv | TRANSCRIPTIONALREGULATOR (Methanothermobacterthermautotrophicus) |
PF01047(MarR) | 5 | LEU A 71LEU A 103VAL A 107LEU A 40ILE A 77 | None | 1.00A | 1s9pD-3bpvA:undetectable | 1s9pD-3bpvA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c87 | ENTEROCHELINESTERASE (Shigellaflexneri) |
PF00756(Esterase)PF11806(DUF3327) | 5 | LEU A 218LEU A 224ALA A 227VAL A 276LEU A 384 | None | 1.10A | 1s9pD-3c87A:undetectable | 1s9pD-3c87A:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LEU A 99ALA A 98GLU A 96LEU A 107ILE A 102 | NoneNoneALF A 501 ( 3.2A)NoneNone | 0.95A | 1s9pD-3cmtA:undetectable | 1s9pD-3cmtA:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LEU A1099ALA A1098GLU A1096LEU A1107ILE A1102 | NoneNoneALF A1501 ( 3.1A)NoneNone | 0.95A | 1s9pD-3cmtA:undetectable | 1s9pD-3cmtA:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LEU A2099ALA A2098GLU A2096LEU A2107ILE A2102 | NoneNoneALF A2501 ( 3.3A)NoneNone | 0.95A | 1s9pD-3cmtA:undetectable | 1s9pD-3cmtA:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LEU A3099ALA A3098GLU A3096LEU A3107ILE A3102 | NoneNoneALF A3501 ( 3.2A)NoneNone | 0.95A | 1s9pD-3cmtA:undetectable | 1s9pD-3cmtA:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LEU A4099ALA A4098GLU A4096LEU A4107ILE A4102 | NoneNoneALF A4501 ( 3.3A)NoneNone | 0.94A | 1s9pD-3cmtA:undetectable | 1s9pD-3cmtA:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LEU A 99ALA A 98GLU A 96LEU A 107ILE A 102 | NoneNoneALF A 501 ( 2.4A)NoneNone | 1.01A | 1s9pD-3cmuA:undetectable | 1s9pD-3cmuA:7.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LEU A2099ALA A2098GLU A2096LEU A2107ILE A2102 | NoneNoneALF A2501 ( 2.5A)NoneNone | 1.01A | 1s9pD-3cmuA:undetectable | 1s9pD-3cmuA:7.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 5 | LEU A3099ALA A3098GLU A3096LEU A3107ILE A3102 | NoneNoneALF A3501 ( 2.7A)NoneNone | 1.01A | 1s9pD-3cmuA:undetectable | 1s9pD-3cmuA:7.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gir | AMINOMETHYLTRANSFERASE (Bartonellahenselae) |
PF01571(GCV_T)PF08669(GCV_T_C) | 5 | LEU A 149LEU A 65ALA A 123LEU A 109ILE A 147 | None | 0.97A | 1s9pD-3girA:undetectable | 1s9pD-3girA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ht4 | ALUMINUM RESISTANCEPROTEIN (Bacillus cereus) |
PF06838(Met_gamma_lyase) | 5 | LEU A 307LEU A 304ALA A 301VAL A 394ILE A 14 | None | 1.05A | 1s9pD-3ht4A:undetectable | 1s9pD-3ht4A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3icu | E3 UBIQUITIN-PROTEINLIGASE RNF128 (Homo sapiens) |
PF02225(PA) | 5 | LEU A 84LEU A 117ALA A 143LEU A 47ILE A 179 | None | 1.09A | 1s9pD-3icuA:undetectable | 1s9pD-3icuA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k4u | BINDING COMPONENT OFABC TRANSPORTER (Wolinellasuccinogenes) |
PF00497(SBP_bac_3) | 5 | LEU A 204ALA A 33LEU A 44LEU A 1ILE A 193 | None | 0.89A | 1s9pD-3k4uA:undetectable | 1s9pD-3k4uA:25.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mkq | COATOMERBETA'-SUBUNIT (Saccharomycescerevisiae) |
PF00400(WD40)PF04053(Coatomer_WDAD) | 5 | LEU A 726LEU A 729ALA A 733LEU A 715ILE A 748 | None | 1.04A | 1s9pD-3mkqA:undetectable | 1s9pD-3mkqA:15.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ncc | PROLACTIN (Homo sapiens) |
PF00103(Hormone_1) | 5 | LEU A 15LEU A 18ALA A 22LEU A 126ILE A 193 | None | 1.12A | 1s9pD-3nccA:undetectable | 1s9pD-3nccA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o75 | FRUCTOSE TRANSPORTSYSTEM REPRESSORFRUR (Pseudomonasputida) |
PF00532(Peripla_BP_1) | 5 | ALA A 120LEU A 142TYR A 313LEU A 151ILE A 147 | None | 1.11A | 1s9pD-3o75A:undetectable | 1s9pD-3o75A:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rht | (GATASE1)-LIKEPROTEIN (Planctopiruslimnophila) |
PF07090(GATase1_like) | 5 | LEU A 190LEU A 191VAL A 251LEU A 82ILE A 148 | None | 1.12A | 1s9pD-3rhtA:undetectable | 1s9pD-3rhtA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ry9 | ANCESTRALGLUCOCORTICOIDRECEPTOR 1 (syntheticconstruct) |
PF00104(Hormone_recep) | 5 | LEU A 29LEU A 32MET A 70ARG A 80LEU A 111 | 1CA A 249 ( 3.8A)1CA A 249 (-3.9A)1CA A 249 ( 3.8A)1CA A 249 (-3.5A)None | 0.81A | 1s9pD-3ry9A:28.5 | 1s9pD-3ry9A:28.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sze | SERINE PROTEASE ESPP (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | LEU A 762LEU A 794ALA A 812VAL A 850ILE A 738 | None | 1.14A | 1s9pD-3szeA:undetectable | 1s9pD-3szeA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ufg | GLYCYL-TRNASYNTHETASE ALPHASUBUNIT (Campylobacterjejuni) |
PF02091(tRNA-synt_2e) | 5 | LEU A 43LEU A 40ALA A 37TYR A 237LEU A 120 | None | 1.10A | 1s9pD-3ufgA:undetectable | 1s9pD-3ufgA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wh7 | BETA-GLUCOSIDASE (metagenomes) |
PF00232(Glyco_hydro_1) | 5 | LEU A 71LEU A 68TYR A 76LEU A 402ILE A 429 | None | 0.81A | 1s9pD-3wh7A:undetectable | 1s9pD-3wh7A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wiw | GLYCOSYL HYDROLASEFAMILY 88 (Pedobacterheparinus) |
PF07470(Glyco_hydro_88) | 5 | LEU A 138LEU A 141ALA A 145LEU A 182TYR A 122 | None | 0.88A | 1s9pD-3wiwA:undetectable | 1s9pD-3wiwA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wkh | CELLOBIOSE2-EPIMERASE (Rhodothermusmarinus) |
PF07221(GlcNAc_2-epim) | 5 | LEU A 240LEU A 268ARG A 401LEU A 202ILE A 232 | None | 1.12A | 1s9pD-3wkhA:undetectable | 1s9pD-3wkhA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4avc | LYSINEACETYLTRANSFERASE (Mycobacteriumtuberculosis) |
PF00027(cNMP_binding)PF13302(Acetyltransf_3) | 5 | ALA A 135LEU A 139VAL A 328TYR A 204LEU A 162 | PEG A1335 (-3.9A)NoneNoneNoneNone | 1.11A | 1s9pD-4avcA:undetectable | 1s9pD-4avcA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c41 | CORTICOSTEROID-BINDING GLOBULIN (Homo sapiens) |
PF00079(Serpin) | 5 | LEU A 68LEU A 67VAL A 344HIS A 84ILE A 83 | None | 1.13A | 1s9pD-4c41A:undetectable | 1s9pD-4c41A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4con | ANAEROBICRIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE (Thermotogamaritima) |
PF13597(NRDD) | 5 | LEU A 130VAL A 134LEU A 152HIS A 208ILE A 211 | None | 1.09A | 1s9pD-4conA:undetectable | 1s9pD-4conA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ddw | REVERSE GYRASE (Thermotogamaritima) |
PF00270(DEAD)PF01131(Topoisom_bac)PF01751(Toprim) | 5 | LEU A 455LEU A 393ALA A 398LEU A 403VAL A 406 | None | 1.15A | 1s9pD-4ddwA:undetectable | 1s9pD-4ddwA:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gul | PIRIN (Homo sapiens) |
PF02678(Pirin)PF05726(Pirin_C) | 5 | LEU A 116LEU A 246VAL A 250LEU A 36ILE A 241 | None | 1.09A | 1s9pD-4gulA:undetectable | 1s9pD-4gulA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hlu | ENERGY-COUPLINGFACTOR TRANSPORTERATP-BINDING PROTEINECFA (Thermotogamaritima) |
no annotation | 5 | LEU D1051LEU D1052ALA D1054VAL D1017TYR D1012 | NoneNoneNoneADP D1301 (-4.6A)ADP D1301 (-3.6A) | 1.14A | 1s9pD-4hluD:undetectable | 1s9pD-4hluD:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jgv | NUCLEAR RECEPTORSUBFAMILY 4 GROUP AMEMBER 1 (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 446LEU A 449ALA A 452VAL A 498ILE A 417 | NoneNoneNoneGOL A 606 ( 4.1A)None | 1.10A | 1s9pD-4jgvA:22.1 | 1s9pD-4jgvA:28.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 7 | LEU A 280LEU A 283ALA A 287GLU A 290MET A 321LEU A 324ARG A 331 | None | 0.46A | 1s9pD-4n1yA:30.0 | 1s9pD-4n1yA:27.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nme | PROLINEDEHYDROGENASE ANDDELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE (Geobactersulfurreducens) |
PF00171(Aldedh)PF01619(Pro_dh) | 5 | LEU A 275LEU A 304ALA A 356VAL A 366ILE A 273 | NoneNoneP5F A1101 ( 3.7A)NoneNone | 1.01A | 1s9pD-4nmeA:undetectable | 1s9pD-4nmeA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ozt | RETINOID X RECEPTOR (Pediculushumanus) |
PF00104(Hormone_recep) | 5 | LEU U 355LEU U 358LEU U 242LEU U 300ILE U 306 | None | 1.09A | 1s9pD-4oztU:19.4 | 1s9pD-4oztU:28.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4poo | PUTATIVE RNAMETHYLASE (Bacillussubtilis) |
PF06962(rRNA_methylase) | 5 | LEU A 13LEU A 135ALA A 98LEU A 126ILE A 183 | None | 1.09A | 1s9pD-4pooA:undetectable | 1s9pD-4pooA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) |
PF00704(Glyco_hydro_18) | 5 | LEU A 219LEU A 271TYR A 383LEU A 260ILE A 217 | None | 1.13A | 1s9pD-4q22A:undetectable | 1s9pD-4q22A:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uav | HALOACIDDEHALOGENASE-LIKEHYDROLASEDOMAIN-CONTAININGPROTEIN AT3G48420 (Arabidopsisthaliana) |
PF13419(HAD_2) | 5 | LEU A 212LEU A 213ALA A 218VAL A 194ILE A 169 | None | 1.12A | 1s9pD-4uavA:undetectable | 1s9pD-4uavA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udb | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 766LEU A 769ALA A 773MET A 807LEU A 810ARG A 817 | CV7 A1987 (-3.6A)CV7 A1987 (-4.1A)CV7 A1987 (-3.5A)CV7 A1987 ( 3.9A)CV7 A1987 (-4.0A)CV7 A1987 (-3.7A) | 0.58A | 1s9pD-4udbA:27.5 | 1s9pD-4udbA:25.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uip | REPEBODY (RAC1) (Eptatretusburgeri;Listeriamonocytogenes;syntheticconstruct) |
PF11921(DUF3439)PF12354(Internalin_N)PF13855(LRR_8) | 5 | LEU B 115LEU B 91ALA B 70VAL B 57LEU B 98 | None | 1.14A | 1s9pD-4uipB:undetectable | 1s9pD-4uipB:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wj3 | ASPARTYL/GLUTAMYL-TRNA(ASN/GLN)AMIDOTRANSFERASESUBUNIT B (Pseudomonasaeruginosa) |
PF02637(GatB_Yqey)PF02934(GatB_N) | 5 | LEU B 61ALA B 65LEU B 176LEU B 15ILE B 99 | None | 1.06A | 1s9pD-4wj3B:undetectable | 1s9pD-4wj3B:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yyf | BETA-N-ACETYLHEXOSAMINIDASE (Mycolicibacteriumsmegmatis) |
PF00933(Glyco_hydro_3) | 6 | ALA A 208LEU A 261VAL A 267ARG A 216HIS A 226ILE A 192 | NoneNoneNoneNoneACT A 401 (-3.5A)None | 1.19A | 1s9pD-4yyfA:undetectable | 1s9pD-4yyfA:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5apg | TSR3 (Vulcanisaetadistributa) |
PF04034(Ribo_biogen_C) | 5 | ALA A 118LEU A 93TYR A 153LEU A 164ILE A 145 | NoneEEM A1185 (-3.9A)NoneNoneNone | 1.10A | 1s9pD-5apgA:undetectable | 1s9pD-5apgA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dud | YBGK (Escherichiacoli) |
PF02626(CT_A_B) | 5 | LEU A 150MET A 94VAL A 44LEU A 113ILE A 4 | None | 1.11A | 1s9pD-5dudA:undetectable | 1s9pD-5dudA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e4v | NUCLEOPROTEIN,PHOSPHOPROTEIN (Measlesmorbillivirus) |
PF00973(Paramyxo_ncap)PF13825(Paramyxo_PNT) | 5 | LEU A 33LEU A 36LEU A 50LEU A 58ILE A 151 | None | 1.07A | 1s9pD-5e4vA:undetectable | 1s9pD-5e4vA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e78 | BIFUNCTIONALP-450/NADPH-P450REDUCTASE (Bacillusmegaterium) |
PF00067(p450) | 5 | LEU A 418ALA A 294GLU A 293LEU A 311LEU A 273 | None | 0.98A | 1s9pD-5e78A:2.7 | 1s9pD-5e78A:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5evy | SALICYLATEHYDROXYLASE (Pseudomonasputida) |
PF01494(FAD_binding_3) | 5 | LEU X 329ALA X 336LEU X 24VAL X 10ILE X 58 | None | 0.99A | 1s9pD-5evyX:undetectable | 1s9pD-5evyX:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5foi | MYCINAMICIN VIII C21METHYL HYDROXYLASE (Micromonosporagriseorubida) |
PF00067(p450) | 5 | LEU A 147LEU A 198ALA A 202GLU A 205LEU A 338 | NoneNoneNoneNoneHEM A 413 ( 4.1A) | 1.15A | 1s9pD-5foiA:undetectable | 1s9pD-5foiA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k04 | UNCHARACTERIZEDPROTEIN (Candidaalbicans) |
PF09797(NatB_MDM20) | 6 | LEU A 210LEU A 213ALA A 217GLU A 220LEU A 188ILE A 183 | None | 1.39A | 1s9pD-5k04A:undetectable | 1s9pD-5k04A:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kum | ATP-SENSITIVE INWARDRECTIFIER POTASSIUMCHANNEL 12 (Gallus gallus) |
PF01007(IRK) | 5 | LEU A 280GLU A 320ARG A 44HIS A 272ILE A 274 | None | 1.13A | 1s9pD-5kumA:undetectable | 1s9pD-5kumA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m59 | PRE-MRNA SPLICINGHELICASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 5 | ALA A1427LEU A1415TYR A1429LEU A1542ILE A1556 | None | 1.14A | 1s9pD-5m59A:undetectable | 1s9pD-5m59A:9.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mwp | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
no annotation | 5 | LEU A 766LEU A 769ALA A 773MET A 807ARG A 817 | ECV A1101 ( 3.9A)ECV A1101 (-4.7A)ECV A1101 (-3.8A)ECV A1101 (-3.6A)ECV A1101 (-4.0A) | 0.50A | 1s9pD-5mwpA:28.7 | 1s9pD-5mwpA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nm8 | PIPY (Synechococcuselongatus) |
PF01168(Ala_racemase_N) | 5 | LEU A 115LEU A 113VAL A 82ARG A 109LEU A 96 | None | 1.13A | 1s9pD-5nm8A:undetectable | 1s9pD-5nm8A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nnp | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF00583(Acetyltransf_1) | 5 | LEU B 131ALA B 127VAL B 121TYR B 132ILE B 96 | NoneNoneNoneNoneGOL B 201 (-4.8A) | 1.13A | 1s9pD-5nnpB:undetectable | 1s9pD-5nnpB:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o9w | THEBAINE6-O-DEMETHYLASE (Papaversomniferum) |
no annotation | 5 | LEU A 75LEU A 78ALA A 81VAL A 278LEU A 197 | EDO A 403 (-3.7A)NoneNoneNoneNone | 1.06A | 1s9pD-5o9wA:undetectable | 1s9pD-5o9wA:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5obu | CHAPERONE PROTEINDNAK (Mycoplasmagenitalium) |
no annotation | 5 | LEU A 103LEU A 106ALA A 110LEU A 31ILE A 123 | None | 1.04A | 1s9pD-5obuA:undetectable | 1s9pD-5obuA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5obw | CHAPERONE PROTEINDNAK (Mycoplasmagenitalium) |
no annotation | 5 | LEU A 103LEU A 106ALA A 110LEU A 31ILE A 123 | None | 1.06A | 1s9pD-5obwA:undetectable | 1s9pD-5obwA:17.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 7 | LEU A 298ALA A 302GLU A 305MET A 336LEU A 339ARG A 346HIS A 475 | EST A 601 (-4.1A)EST A 601 ( 3.9A)EST A 601 (-2.4A)EST A 601 ( 3.7A)EST A 601 (-3.9A)EST A 601 (-4.1A)EST A 601 (-4.4A) | 0.40A | 1s9pD-5toaA:28.8 | 1s9pD-5toaA:36.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uai | METHIONYL-TRNAFORMYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00551(Formyl_trans_N)PF02911(Formyl_trans_C) | 6 | LEU A 172LEU A 175ALA A 179GLU A 182LEU A 153LEU A 114 | None | 1.35A | 1s9pD-5uaiA:undetectable | 1s9pD-5uaiA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wm9 | RV0078 (Mycobacteriumtuberculosis) |
no annotation | 5 | LEU A 159ALA A 166LEU A 191LEU A 199ILE A 142 | LEU A 159 ( 0.6A)ALA A 166 ( 0.0A)LEU A 191 ( 0.5A)LEU A 199 ( 0.6A)ILE A 142 ( 0.7A) | 1.13A | 1s9pD-5wm9A:undetectable | 1s9pD-5wm9A:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wq0 | STAGE 0 SPORULATIONPROTEIN (Paenisporosarcinasp. TG-14) |
no annotation | 5 | LEU B 15ALA B 9LEU B 53VAL B 6LEU B 115 | None | 1.00A | 1s9pD-5wq0B:undetectable | 1s9pD-5wq0B:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 5 | LEU A 755LEU A 752ALA A 749VAL A 562ILE A 464 | None | 1.15A | 1s9pD-6d95A:undetectable | 1s9pD-6d95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6etz | BETA-GALACTOSIDASE (Arthrobactersp. 32cB) |
no annotation | 5 | LEU A1006LEU A 842VAL A 829TYR A 831ILE A 937 | None | 1.09A | 1s9pD-6etzA:undetectable | 1s9pD-6etzA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ezn | DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEINGLYCOSYLTRANSFERASESUBUNIT WBP1 (Saccharomycescerevisiae) |
no annotation | 5 | LEU G 364GLU G 252ARG G 167HIS G 307ILE G 264 | None | 1.06A | 1s9pD-6eznG:undetectable | 1s9pD-6eznG:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gu8 | - (-) |
no annotation | 5 | ALA A 233LEU A 253VAL A 251LEU A 186ILE A 138 | None | 1.07A | 1s9pD-6gu8A:undetectable | 1s9pD-6gu8A:undetectable |