SIMILAR PATTERNS OF AMINO ACIDS FOR 1S9P_C_DESC500_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e32 | P97 (Mus musculus) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2) | 5 | LEU A 411LEU A 414CYH A 415ALA A 418MET A 449 | None | 0.70A | 1s9pC-1e32A:undetectable | 1s9pC-1e32A:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1efp | PROTEIN (ELECTRONTRANSFERFLAVOPROTEIN) (Paracoccusdenitrificans) |
PF01012(ETF) | 5 | LEU B 99LEU B 105ALA B 106LEU B 139VAL B 177 | None | 1.07A | 1s9pC-1efpB:undetectable | 1s9pC-1efpB:23.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j5x | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Thermotogamaritima) |
PF01380(SIS) | 5 | LEU A 156LEU A 159LEU A 162ALA A 163LEU A 66 | None | 1.02A | 1s9pC-1j5xA:undetectable | 1s9pC-1j5xA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1khy | CLPB PROTEIN (Escherichiacoli) |
PF02861(Clp_N) | 5 | LEU A 110LEU A 113ALA A 114GLU A 117LEU A 93 | None | 0.94A | 1s9pC-1khyA:undetectable | 1s9pC-1khyA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lb3 | FERRITIN LIGHT CHAIN1 (Mus musculus) |
PF00210(Ferritin) | 5 | LEU A 120LEU A 117LEU A 114ALA A 113LEU A 26 | None | 0.68A | 1s9pC-1lb3A:undetectable | 1s9pC-1lb3A:25.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 346LEU A 349ALA A 350GLU A 353LEU A 387ARG A 394 | EST A 1 (-4.4A)EST A 1 ( 4.8A)EST A 1 ( 3.7A)EST A 1 (-2.8A)EST A 1 (-4.0A)EST A 1 (-3.7A) | 0.33A | 1s9pC-1pcgA:27.4 | 1s9pC-1pcgA:36.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ug3 | EUKARYOTIC PROTEINSYNTHESIS INITIATIONFACTOR 4G (Homo sapiens) |
PF02020(W2)PF02847(MA3) | 5 | LEU A1532LEU A1529LEU A1526ALA A1525LEU A1516 | None | 0.93A | 1s9pC-1ug3A:undetectable | 1s9pC-1ug3A:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ug3 | EUKARYOTIC PROTEINSYNTHESIS INITIATIONFACTOR 4G (Homo sapiens) |
PF02020(W2)PF02847(MA3) | 5 | LEU A1532LEU A1529LEU A1526ALA A1525VAL A1555 | None | 1.01A | 1s9pC-1ug3A:undetectable | 1s9pC-1ug3A:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v9c | PRECORRIN-8X METHYLMUTASE (Thermusthermophilus) |
PF02570(CbiC) | 5 | LEU A 197LEU A 200LEU A 203ALA A 204ILE A 69 | None | 0.77A | 1s9pC-1v9cA:undetectable | 1s9pC-1v9cA:24.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wvt | HYPOTHETICAL PROTEINST2180 (Sulfurisphaeratokodaii) |
PF01923(Cob_adeno_trans) | 5 | LEU A 36LEU A 33LEU A 30ALA A 29LEU A 129 | None | 0.92A | 1s9pC-1wvtA:undetectable | 1s9pC-1wvtA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wym | TRANSGELIN-2 (Homo sapiens) |
PF00307(CH) | 5 | LEU A 121LEU A 124LEU A 127ALA A 128ILE A 26 | None | 1.02A | 1s9pC-1wymA:undetectable | 1s9pC-1wymA:21.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xb7 | STEROID HORMONERECEPTOR ERR1 (Homo sapiens) |
PF00104(Hormone_recep) | 8 | LEU A 324CYH A 325LEU A 327GLU A 331MET A 362LEU A 365VAL A 369ARG A 372 | None | 0.41A | 1s9pC-1xb7A:28.9 | 1s9pC-1xb7A:58.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygu | LEUKOCYTE COMMONANTIGEN (Homo sapiens) |
PF00102(Y_phosphatase) | 5 | LEU A1157LEU A1160ALA A1164LEU A 897VAL A 895 | None | 0.86A | 1s9pC-1yguA:undetectable | 1s9pC-1yguA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zh8 | OXIDOREDUCTASE (Thermotogamaritima) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | LEU A 305LEU A 308ALA A 309GLU A 312LEU A 327 | None | 1.08A | 1s9pC-1zh8A:undetectable | 1s9pC-1zh8A:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a0j | PTS SYSTEM, NITROGENREGULATORY IIAPROTEIN (Neisseriameningitidis) |
PF00359(PTS_EIIA_2) | 5 | LEU A 114LEU A 117LEU A 120ALA A 121LEU A 59 | None | 0.90A | 1s9pC-2a0jA:undetectable | 1s9pC-2a0jA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aja | ANKYRIN REPEATFAMILY PROTEIN (Legionellapneumophila) |
no annotation | 6 | LEU A 144LEU A 147CYH A 148LEU A 150ALA A 151GLU A 119 | None | 1.29A | 1s9pC-2ajaA:undetectable | 1s9pC-2ajaA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aja | ANKYRIN REPEATFAMILY PROTEIN (Legionellapneumophila) |
no annotation | 5 | LEU A 179LEU A 182CYH A 183LEU A 185ALA A 186 | None | 0.88A | 1s9pC-2ajaA:undetectable | 1s9pC-2ajaA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 701LEU A 704LEU A 707MET A 742ARG A 752 | NoneBHM A 1 (-4.0A)BHM A 1 ( 4.2A)BHM A 1 ( 4.0A)BHM A 1 (-3.8A) | 0.59A | 1s9pC-2ax9A:26.4 | 1s9pC-2ax9A:27.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2btv | PROTEIN (VP7 COREPROTEIN) (Bluetonguevirus) |
no annotation | 5 | LEU P 310LEU P 313LEU P 316ALA P 317ILE P 267 | None | 0.56A | 1s9pC-2btvP:undetectable | 1s9pC-2btvP:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c2g | THREONINE SYNTHASE (Arabidopsisthaliana) |
PF00291(PALP) | 5 | LEU A 415LEU A 412LEU A 409ALA A 408ILE A 378 | None | 1.02A | 1s9pC-2c2gA:undetectable | 1s9pC-2c2gA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb1 | O-ACETYL HOMOSERINESULFHYDRYLASE (Thermusthermophilus) |
PF01053(Cys_Met_Meta_PP) | 5 | LEU A 159LEU A 162LEU A 165ALA A 166VAL A 99 | None | 0.98A | 1s9pC-2cb1A:undetectable | 1s9pC-2cb1A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cu5 | CONSERVEDHYPOTHETICAL PROTEINTT1486 (Thermusthermophilus) |
PF01894(UPF0047) | 5 | LEU A 60LEU A 63LEU A 66ALA A 67LEU A 85 | None | 0.95A | 1s9pC-2cu5A:undetectable | 1s9pC-2cu5A:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e2c | UBIQUITINCONJUGATING ENZYME (Spisulasolidissima) |
PF00179(UQ_con) | 5 | LEU A 132LEU A 135LEU A 138VAL A 107ILE A 50 | None | 1.07A | 1s9pC-2e2cA:undetectable | 1s9pC-2e2cA:20.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gpv | ESTROGEN-RELATEDRECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 10 | LEU A 265LEU A 268LEU A 271ALA A 272GLU A 275MET A 306LEU A 309VAL A 313ARG A 316TYR A 326 | NoneOHT A 500 (-4.1A)OHT A 500 ( 4.4A)OHT A 500 (-3.5A)OHT A 500 (-2.6A)OHT A 500 (-3.9A)OHT A 500 ( 4.0A)NoneOHT A 500 (-3.8A)OHT A 500 (-4.5A) | 0.38A | 1s9pC-2gpvA:34.3 | 1s9pC-2gpvA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gpv | ESTROGEN-RELATEDRECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 8 | LEU A 265LEU A 268MET A 306LEU A 309VAL A 313ARG A 316TYR A 326ILE A 438 | NoneOHT A 500 (-4.1A)OHT A 500 (-3.9A)OHT A 500 ( 4.0A)NoneOHT A 500 (-3.8A)OHT A 500 (-4.5A)None | 0.71A | 1s9pC-2gpvA:34.3 | 1s9pC-2gpvA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gpv | ESTROGEN-RELATEDRECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 8 | LEU A 268CYH A 269LEU A 271ALA A 272GLU A 275MET A 306LEU A 309ARG A 316 | OHT A 500 (-4.1A)OHT A 500 ( 4.7A)OHT A 500 ( 4.4A)OHT A 500 (-3.5A)OHT A 500 (-2.6A)OHT A 500 (-3.9A)OHT A 500 ( 4.0A)OHT A 500 (-3.8A) | 0.62A | 1s9pC-2gpvA:34.3 | 1s9pC-2gpvA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l7n | TALIN-1 (Mus musculus) |
no annotation | 5 | LEU A1105LEU A1106ALA A1103VAL A1192ILE A1119 | None | 1.07A | 1s9pC-2l7nA:undetectable | 1s9pC-2l7nA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o7t | TRANSCRIPTIONALREGULATOR (Corynebacteriumglutamicum) |
PF00440(TetR_N) | 5 | LEU A 130LEU A 133ALA A 134VAL A 84ILE A 150 | NoneNoneNoneNoneUNL A 200 ( 4.3A) | 1.03A | 1s9pC-2o7tA:undetectable | 1s9pC-2o7tA:19.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 346LEU A 349ALA A 350GLU A 353LEU A 387ARG A 394 | EST A 596 (-4.4A)EST A 596 ( 4.1A)EST A 596 ( 3.9A)EST A 596 (-2.7A)EST A 596 ( 4.2A)EST A 596 (-4.0A) | 0.49A | 1s9pC-2ocfA:28.3 | 1s9pC-2ocfA:31.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pmi | CYCLIN-DEPENDENTPROTEIN KINASE PHO85 (Saccharomycescerevisiae) |
PF00069(Pkinase) | 5 | CYH A 197LEU A 199ALA A 200LEU A 258ILE A 221 | None | 1.07A | 1s9pC-2pmiA:undetectable | 1s9pC-2pmiA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pz0 | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Caldanaerobactersubterraneus) |
PF03009(GDPD) | 5 | LEU A 214LEU A 192LEU A 171ARG A 186ILE A 199 | None | 1.07A | 1s9pC-2pz0A:undetectable | 1s9pC-2pz0A:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q3y | ANCESTRAL CORTICIODRECEPTOR (unidentified) |
PF00104(Hormone_recep) | 6 | LEU A 29LEU A 32LEU A 35ALA A 36MET A 70ARG A 80 | 1CA A 247 ( 3.6A)1CA A 247 (-4.0A)1CA A 247 ( 4.4A)1CA A 247 (-3.6A)1CA A 247 ( 3.8A)1CA A 247 (-3.8A) | 0.46A | 1s9pC-2q3yA:26.6 | 1s9pC-2q3yA:27.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vw8 | PA1000 (Pseudomonasaeruginosa) |
PF00753(Lactamase_B) | 6 | LEU A 208LEU A 205LEU A 202VAL A 194TYR A 201ILE A 154 | None | 1.38A | 1s9pC-2vw8A:undetectable | 1s9pC-2vw8A:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wdw | PUTATIVE HEXOSEOXIDASE (Nonomuraeagerenzanensis) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | LEU A 179ALA A 416LEU A 502VAL A 505ILE A 160 | None | 0.90A | 1s9pC-2wdwA:undetectable | 1s9pC-2wdwA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xax | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1SUBUNIT ALPHA (Escherichiacoli) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 5 | LEU A 478LEU A 481LEU A 484ALA A 485ILE A 547 | None | 1.05A | 1s9pC-2xaxA:undetectable | 1s9pC-2xaxA:13.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsj | SULFITE REDUCTASEALPHA SUBUNIT (Desulfomicrobiumnorvegicum) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | LEU A 115LEU A 118CYH A 119LEU A 121VAL A 100 | None | 1.05A | 1s9pC-2xsjA:undetectable | 1s9pC-2xsjA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y0m | PROBABLE HISTONEACETYLTRANSFERASEMYST1 (Homo sapiens) |
PF01853(MOZ_SAS) | 5 | LEU A 263CYH A 264LEU A 266ALA A 267LEU A 318 | NoneALY A 274 ( 3.4A)NoneALY A 274 ( 4.0A)ACO A1450 (-4.2A) | 0.81A | 1s9pC-2y0mA:undetectable | 1s9pC-2y0mA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3s | TAML (Streptomycessp. 307-9) |
PF01565(FAD_binding_4)PF08031(BBE) | 5 | LEU A 150ALA A 390LEU A 476VAL A 479ILE A 131 | None | 0.87A | 1s9pC-2y3sA:undetectable | 1s9pC-2y3sA:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2za8 | FERRITIN LIGHT CHAIN (Equus caballus) |
PF00210(Ferritin) | 5 | LEU A 117LEU A 114LEU A 111ALA A 110LEU A 23 | None | 0.86A | 1s9pC-2za8A:undetectable | 1s9pC-2za8A:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b5q | PUTATIVE SULFATASEYIDJ (Bacteroidesthetaiotaomicron) |
PF00884(Sulfatase)PF16347(DUF4976) | 5 | LEU A 335LEU A 338CYH A 339LEU A 341ALA A 342 | None | 1.07A | 1s9pC-3b5qA:undetectable | 1s9pC-3b5qA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c4n | UNCHARACTERIZEDPROTEIN DR_0571 (Deinococcusradiodurans) |
PF01266(DAO) | 5 | LEU A 384LEU A 390ALA A 391LEU A 55VAL A 41 | None | 0.75A | 1s9pC-3c4nA:undetectable | 1s9pC-3c4nA:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fdb | PUTATIVEPLP-DEPENDENTBETA-CYSTATHIONASE (Corynebacteriumdiphtheriae) |
PF00155(Aminotran_1_2) | 5 | LEU A 171LEU A 174CYH A 175LEU A 177ALA A 178 | None | 0.69A | 1s9pC-3fdbA:undetectable | 1s9pC-3fdbA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gir | AMINOMETHYLTRANSFERASE (Bartonellahenselae) |
PF01571(GCV_T)PF08669(GCV_T_C) | 5 | LEU A 149LEU A 65ALA A 123LEU A 109ILE A 147 | None | 0.98A | 1s9pC-3girA:undetectable | 1s9pC-3girA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gl5 | PUTATIVE DSBAOXIDOREDUCTASESCO1869 (Streptomycescoelicolor) |
PF01323(DSBA) | 5 | LEU A 101LEU A 104LEU A 107ALA A 108ILE A 9 | None | 0.83A | 1s9pC-3gl5A:undetectable | 1s9pC-3gl5A:24.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hz6 | XYLULOKINASE (Chromobacteriumviolaceum) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | LEU A 439LEU A 442LEU A 445ALA A 446LEU A 236 | None | 0.91A | 1s9pC-3hz6A:undetectable | 1s9pC-3hz6A:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kba | PROGESTERONERECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 715LEU A 718LEU A 721MET A 756ARG A 766 | WOW A 1 (-3.9A)WOW A 1 (-4.2A)WOW A 1 ( 4.3A)WOW A 1 ( 4.1A)WOW A 1 (-3.8A) | 0.49A | 1s9pC-3kbaA:25.4 | 1s9pC-3kbaA:28.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myf | SENSOR PROTEIN (Shewanella sp.W3-18-1) |
PF01627(Hpt) | 5 | LEU A 833LEU A 830LEU A 827ALA A 826LEU A 816 | None | 1.08A | 1s9pC-3myfA:undetectable | 1s9pC-3myfA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ncc | PROLACTIN (Homo sapiens) |
PF00103(Hormone_1) | 5 | LEU A 15LEU A 18ALA A 22LEU A 126ILE A 193 | None | 1.05A | 1s9pC-3nccA:undetectable | 1s9pC-3nccA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3now | UNC-45 PROTEIN,SD10334P (Drosophilamelanogaster) |
PF11701(UNC45-central) | 5 | LEU A 637CYH A 638LEU A 640ALA A 641MET A 681 | None | 1.00A | 1s9pC-3nowA:undetectable | 1s9pC-3nowA:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pm9 | PUTATIVEOXIDOREDUCTASE (Rhodopseudomonaspalustris) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 5 | LEU A 247LEU A 244ALA A 243LEU A 263ILE A 308 | None | 1.05A | 1s9pC-3pm9A:undetectable | 1s9pC-3pm9A:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT N (Escherichiacoli) |
no annotation | 5 | LEU N 79LEU N 82LEU N 85ALA N 86ILE N 248 | LFA N 488 ( 4.8A)NoneNoneNoneNone | 0.99A | 1s9pC-3rkoN:undetectable | 1s9pC-3rkoN:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ry9 | ANCESTRALGLUCOCORTICOIDRECEPTOR 1 (syntheticconstruct) |
PF00104(Hormone_recep) | 5 | LEU A 29LEU A 32LEU A 35MET A 70ARG A 80 | 1CA A 249 ( 3.8A)1CA A 249 (-3.9A)1CA A 249 ( 4.4A)1CA A 249 ( 3.8A)1CA A 249 (-3.5A) | 0.45A | 1s9pC-3ry9A:26.8 | 1s9pC-3ry9A:28.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sze | SERINE PROTEASE ESPP (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | LEU A 762LEU A 794ALA A 812VAL A 850ILE A 738 | None | 1.01A | 1s9pC-3szeA:undetectable | 1s9pC-3szeA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3umv | DEOXYRIBODIPYRIMIDINE PHOTO-LYASE (Oryza sativa) |
PF00875(DNA_photolyase) | 5 | LEU A 94LEU A 97LEU A 100ALA A 101VAL A 72 | None | 1.01A | 1s9pC-3umvA:undetectable | 1s9pC-3umvA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4axv | MPAA (Vibriocampbellii) |
PF04952(AstE_AspA) | 5 | LEU A 146LEU A 143LEU A 140ALA A 139LEU A 28 | None | 0.96A | 1s9pC-4axvA:undetectable | 1s9pC-4axvA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b2g | GH3-1 AUXINCONJUGATING ENZYME (Vitis vinifera) |
PF03321(GH3) | 5 | LEU A 505CYH A 509LEU A 511ALA A 512GLU A 515 | None | 1.05A | 1s9pC-4b2gA:undetectable | 1s9pC-4b2gA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d0n | A-KINASE ANCHORPROTEIN 13 (Homo sapiens) |
PF00169(PH)PF00621(RhoGEF) | 5 | LEU B2141LEU B2149CYH B2146LEU B2148ILE B2019 | None | 1.04A | 1s9pC-4d0nB:undetectable | 1s9pC-4d0nB:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdd | TRANSPORTIN-1 (Homo sapiens) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | LEU A 645LEU A 648LEU A 651ALA A 652TYR A 609 | None | 0.59A | 1s9pC-4fddA:undetectable | 1s9pC-4fddA:14.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdh | CYTOCHROME P45011B2, MITOCHONDRIAL (Homo sapiens) |
PF00067(p450) | 5 | LEU A 324LEU A 327LEU A 330ALA A 331ARG A 341 | None | 0.78A | 1s9pC-4fdhA:undetectable | 1s9pC-4fdhA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4im7 | HYPOTHETICALOXIDOREDUCTASE YDFI (Escherichiacoli) |
PF01232(Mannitol_dh)PF08125(Mannitol_dh_C) | 5 | LEU A 300LEU A 303LEU A 306ALA A 307GLU A 412 | None | 1.02A | 1s9pC-4im7A:undetectable | 1s9pC-4im7A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k2p | T-LYMPHOMA INVASIONANDMETASTASIS-INDUCINGPROTEIN 1 (Homo sapiens) |
PF00169(PH) | 6 | LEU A 639ALA A 643GLU A 612MET A 651VAL A 666ARG A 669 | None | 1.46A | 1s9pC-4k2pA:undetectable | 1s9pC-4k2pA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4leo | RECEPTORTYROSINE-PROTEINKINASE ERBB-3 (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 5 | LEU C 342LEU C 378LEU C 411LEU C 427ILE C 338 | None | 1.06A | 1s9pC-4leoC:undetectable | 1s9pC-4leoC:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 8 | LEU A 280LEU A 283LEU A 286ALA A 287GLU A 290MET A 321LEU A 324ARG A 331 | None | 0.48A | 1s9pC-4n1yA:28.5 | 1s9pC-4n1yA:27.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nme | PROLINEDEHYDROGENASE ANDDELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE (Geobactersulfurreducens) |
PF00171(Aldedh)PF01619(Pro_dh) | 5 | LEU A 275LEU A 304ALA A 356VAL A 366ILE A 273 | NoneNoneP5F A1101 ( 3.7A)NoneNone | 0.91A | 1s9pC-4nmeA:undetectable | 1s9pC-4nmeA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4poo | PUTATIVE RNAMETHYLASE (Bacillussubtilis) |
PF06962(rRNA_methylase) | 5 | LEU A 13LEU A 135ALA A 98LEU A 126ILE A 183 | None | 1.05A | 1s9pC-4pooA:undetectable | 1s9pC-4pooA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2c | CRISPR-ASSOCIATEDHELICASE CAS3 (Thermobaculumterrenum) |
PF00271(Helicase_C) | 5 | LEU A 203CYH A 204LEU A 206ALA A 207LEU A 212 | None | 1.06A | 1s9pC-4q2cA:undetectable | 1s9pC-4q2cA:12.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rn3 | HAD SUPERFAMILYHYDROLASE (Geobactersulfurreducens) |
PF13419(HAD_2) | 5 | LEU A 154LEU A 179GLU A 175LEU A 195ILE A 14 | None | 1.06A | 1s9pC-4rn3A:undetectable | 1s9pC-4rn3A:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udb | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 7 | LEU A 766LEU A 769LEU A 772ALA A 773MET A 807LEU A 810ARG A 817 | CV7 A1987 (-3.6A)CV7 A1987 (-4.1A)CV7 A1987 ( 4.5A)CV7 A1987 (-3.5A)CV7 A1987 ( 3.9A)CV7 A1987 (-4.0A)CV7 A1987 (-3.7A) | 0.58A | 1s9pC-4udbA:25.9 | 1s9pC-4udbA:25.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uzz | INTRAFLAGELLARTRANSPORT COMPLEX BPROTEIN 46CARBOXY-TERMINALPROTEININTRAFLAGELLARTRANSPORTER-LIKEPROTEIN (Tetrahymenathermophila) |
PF12317(IFT46_B_C)no annotation | 5 | LEU A 296CYH A 300LEU A 302ALA A 303LEU B 592 | None | 0.89A | 1s9pC-4uzzA:undetectable | 1s9pC-4uzzA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w9r | UNCHARACTERIZEDPROTEIN (Capnocytophagaochracea) |
PF00756(Esterase) | 5 | LEU A 313LEU A 316ALA A 317TYR A 301ILE A 342 | None | 0.89A | 1s9pC-4w9rA:undetectable | 1s9pC-4w9rA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yyf | BETA-N-ACETYLHEXOSAMINIDASE (Mycolicibacteriumsmegmatis) |
PF00933(Glyco_hydro_3) | 5 | ALA A 208LEU A 261VAL A 267ARG A 216ILE A 192 | None | 1.06A | 1s9pC-4yyfA:undetectable | 1s9pC-4yyfA:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cio | PYRROLOQUINOLINEQUINONE BIOSYNTHESISPROTEIN PQQF (Serratia sp.FS14) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | LEU A 200LEU A 203LEU A 206ALA A 207LEU A 192 | None | 0.98A | 1s9pC-5cioA:undetectable | 1s9pC-5cioA:13.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5czl | GLUCANASE (Raoultellaornithinolytica) |
PF01270(Glyco_hydro_8) | 5 | LEU A 306LEU A 309LEU A 312ALA A 313ARG A 106 | None | 0.91A | 1s9pC-5czlA:undetectable | 1s9pC-5czlA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d91 | AF2299PROTEIN,PHOSPHATIDYLINOSITOL SYNTHASE (Archaeoglobusfulgidus;Renibacteriumsalmoninarum) |
PF01066(CDP-OH_P_transf) | 5 | LEU A 174LEU A 177LEU A 180ALA A 181LEU A 125 | 8K6 A 337 ( 4.9A)NoneNoneNoneNone | 0.99A | 1s9pC-5d91A:undetectable | 1s9pC-5d91A:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dgo | CELL DIVISIONCONTROL PROTEIN 45HOMOLOG (Homo sapiens) |
PF02724(CDC45) | 5 | LEU A 564LEU A 561LEU A 558MET A 537LEU A 549 | SO4 A 607 ( 4.9A)NoneNoneNoneNone | 0.61A | 1s9pC-5dgoA:undetectable | 1s9pC-5dgoA:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dgo | CELL DIVISIONCONTROL PROTEIN 45HOMOLOG (Homo sapiens) |
PF02724(CDC45) | 5 | LEU A 564LEU A 561LEU A 558MET A 537VAL A 506 | SO4 A 607 ( 4.9A)NoneNoneNoneNone | 0.88A | 1s9pC-5dgoA:undetectable | 1s9pC-5dgoA:17.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dlq | EXPORTIN-4 (Mus musculus) |
no annotation | 5 | LEU B 296LEU B 299LEU B 302ALA B 303ILE B 344 | None | 1.00A | 1s9pC-5dlqB:undetectable | 1s9pC-5dlqB:12.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | LEU A 462LEU A 459LEU A 456ALA A 455LEU A 429 | None | 1.04A | 1s9pC-5dqfA:undetectable | 1s9pC-5dqfA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5euf | PROTEASE (Helicobacterpylori) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | LEU A 300LEU A 297ALA A 296LEU A 419VAL A 421 | None | 1.04A | 1s9pC-5eufA:undetectable | 1s9pC-5eufA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fir | 5'-3'EXORIBONUCLEASE 2HOMOLOGPAXT-1 (Caenorhabditiselegans) |
PF03159(XRN_N)PF11952(XTBD) | 6 | LEU B 45LEU B 42CYH B 41LEU B 39TYR B 34ILE A 652 | None | 1.34A | 1s9pC-5firB:undetectable | 1s9pC-5firB:14.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fwm | HEAT SHOCK PROTEINHSP 90 BETA (Homo sapiens) |
PF00183(HSP90)PF02518(HATPase_c) | 5 | LEU A 563CYH A 564LEU A 566VAL A 651ILE A 580 | None | 1.06A | 1s9pC-5fwmA:undetectable | 1s9pC-5fwmA:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hax | NUCLEOPORIN NUP170 (Chaetomiumthermophilum) |
PF08801(Nucleoporin_N) | 5 | LEU A 763LEU A 760LEU A 757ALA A 756LEU A 669 | None | 0.92A | 1s9pC-5haxA:undetectable | 1s9pC-5haxA:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hax | NUCLEOPORIN NUP170 (Chaetomiumthermophilum) |
PF08801(Nucleoporin_N) | 5 | LEU A 763LEU A 760LEU A 757GLU A 753LEU A 669 | None | 0.79A | 1s9pC-5haxA:undetectable | 1s9pC-5haxA:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hb1 | NUCLEOPORIN NUP170 (Chaetomiumthermophilum) |
PF03177(Nucleoporin_C) | 5 | LEU A 763LEU A 760LEU A 757ALA A 756LEU A 669 | None | 1.04A | 1s9pC-5hb1A:undetectable | 1s9pC-5hb1A:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hb1 | NUCLEOPORIN NUP170 (Chaetomiumthermophilum) |
PF03177(Nucleoporin_C) | 5 | LEU A 763LEU A 760LEU A 757GLU A 753LEU A 669 | None | 0.83A | 1s9pC-5hb1A:undetectable | 1s9pC-5hb1A:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxk | ZINC-DEPENDENTPEPTIDASE (Thermusthermophilus) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | LEU A 129LEU A 126LEU A 123ALA A 122LEU A 46 | LEU A 129 ( 0.5A)LEU A 126 ( 0.6A)LEU A 123 ( 0.6A)ALA A 122 ( 0.0A)LEU A 46 ( 0.6A) | 1.00A | 1s9pC-5hxkA:undetectable | 1s9pC-5hxkA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j0l | DESIGNED PROTEIN3L6HC2_2 (syntheticconstruct) |
no annotation | 5 | LEU A 48LEU A 51ALA A 55GLU A 58ILE A 39 | None | 1.06A | 1s9pC-5j0lA:undetectable | 1s9pC-5j0lA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lg8 | FERRITIN LIGHT CHAIN (Homo sapiens) |
PF00210(Ferritin) | 5 | LEU A 120LEU A 117LEU A 114ALA A 113LEU A 26 | None | 0.74A | 1s9pC-5lg8A:undetectable | 1s9pC-5lg8A:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5me3 | SISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii) |
PF12765(Cohesin_HEAT)PF12830(Nipped-B_C) | 5 | LEU A1049LEU A1052ALA A1053LEU A1023ILE A1098 | None | 1.07A | 1s9pC-5me3A:undetectable | 1s9pC-5me3A:12.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mwp | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
no annotation | 6 | LEU A 766LEU A 769LEU A 772ALA A 773MET A 807ARG A 817 | ECV A1101 ( 3.9A)ECV A1101 (-4.7A)ECV A1101 ( 3.9A)ECV A1101 (-3.8A)ECV A1101 (-3.6A)ECV A1101 (-4.0A) | 0.56A | 1s9pC-5mwpA:27.0 | 1s9pC-5mwpA:16.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5toa | ESTROGEN RECEPTORBETA (Homo sapiens) |
PF00104(Hormone_recep) | 7 | LEU A 298LEU A 301ALA A 302GLU A 305MET A 336LEU A 339ARG A 346 | EST A 601 (-4.1A)EST A 601 ( 4.3A)EST A 601 ( 3.9A)EST A 601 (-2.4A)EST A 601 ( 3.7A)EST A 601 (-3.9A)EST A 601 (-4.1A) | 0.32A | 1s9pC-5toaA:28.2 | 1s9pC-5toaA:36.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tul | TETRACYCLINEDESTRUCTASE TET(55) (unculturedbacterium) |
PF01494(FAD_binding_3) | 5 | LEU A 306LEU A 312ALA A 313LEU A 23VAL A 9 | None | 0.96A | 1s9pC-5tulA:undetectable | 1s9pC-5tulA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vtm | TYPE II SECRETIONSYSTEM PROTEIN K (Pseudomonasaeruginosa) |
no annotation | 5 | LEU X 196LEU X 194ALA X 166GLU X 167ILE X 142 | NoneNoneNone CA X 403 ( 2.2A)None | 0.98A | 1s9pC-5vtmX:undetectable | 1s9pC-5vtmX:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xhm | FERRITIN, MIDDLESUBUNIT (Ranacatesbeiana) |
PF00210(Ferritin) | 5 | LEU A 116LEU A 113LEU A 110ALA A 109LEU A 22 | None | 0.69A | 1s9pC-5xhmA:undetectable | 1s9pC-5xhmA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | DNA-DEPENDENTPROTEIN KINASECATALYTIC SUBUNIT (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08163(NUC194) | 5 | LEU C1915LEU C1918CYH C1919ALA C1922GLU C1925 | None | 0.42A | 1s9pC-5y3rC:undetectable | 1s9pC-5y3rC:4.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zvs | VP2 (Aquareovirus C) |
no annotation | 5 | LEU 2 235LEU 2 238LEU 2 241ALA 2 242GLU 2 255 | None | 1.06A | 1s9pC-5zvs2:undetectable | 1s9pC-5zvs2:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bar | ROD SHAPEDETERMINING PROTEINRODA (Thermusthermophilus) |
no annotation | 5 | LEU A 112LEU A 115LEU A 118ALA A 119LEU A 298 | None | 1.05A | 1s9pC-6barA:undetectable | 1s9pC-6barA:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6brs | PUTATIVE ZINCPROTEASE (Pectobacteriumatrosepticum) |
no annotation | 5 | LEU A 826LEU A 829ALA A 833GLU A 836ILE A 794 | None | 0.88A | 1s9pC-6brsA:undetectable | 1s9pC-6brsA:14.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c08 | SODIUM-COUPLEDNEUTRAL AMINO ACIDTRANSPORTER 9 (Danio rerio) |
no annotation | 5 | LEU C 500CYH C 501LEU C 503ALA C 504ILE C 198 | None | 0.86A | 1s9pC-6c08C:2.3 | 1s9pC-6c08C:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cmo | CHIMERA PROTEIN OFSOLUBLE CYTOCHROMEB562 AND RHODOPSIN (Escherichiacoli;Homo sapiens) |
no annotation | 5 | LEU R 125LEU R 128LEU R 131ALA R 132TYR R 306 | None | 0.88A | 1s9pC-6cmoR:undetectable | 1s9pC-6cmoR:16.82 |