SIMILAR PATTERNS OF AMINO ACIDS FOR 1S9P_B_DESB459_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
19hc PROTEIN (NINE-HAEM
CYTOCHROME C)

(Desulfovibrio
desulfuricans) 		PF02085
(Cytochrom_CIII) 		3 LEU A 213
HIS A 218
ILE A 208
 HEM  A 303 (-3.8A)
HEM  A 304 (-3.2A)
HEM  A 304 (-4.1A)
 0.65A 1s9pB-19hcA:
undetectable		 1s9pB-19hcA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a2o CHEB METHYLESTERASE

(Salmonella
enterica) 		PF00072
(Response_reg)
PF01339
(CheB_methylest) 		3 LEU A 117
HIS A  26
ILE A  22
 None
 0.67A 1s9pB-1a2oA:
0.0		 1s9pB-1a2oA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1am5 PEPSIN

(Gadus morhua) 		PF00026
(Asp) 		3 LEU A 101
HIS A  44
ILE A  83
 None
 0.69A 1s9pB-1am5A:
undetectable		 1s9pB-1am5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezv UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
14 KD PROTEIN

(Saccharomyces
cerevisiae) 		PF02271
(UCR_14kD) 		3 LEU F  41
HIS F  79
ILE F  75
 None
 0.54A 1s9pB-1ezvF:
undetectable		 1s9pB-1ezvF:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gy8 UDP-GALACTOSE
4-EPIMERASE

(Trypanosoma
brucei) 		PF01370
(Epimerase) 		3 LEU A 227
HIS A 325
ILE A 234
 None
 0.65A 1s9pB-1gy8A:
0.0		 1s9pB-1gy8A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1idj PECTIN LYASE A

(Aspergillus
niger) 		PF00544
(Pec_lyase_C) 		3 LEU A 329
HIS A 247
ILE A 337
 None
 0.67A 1s9pB-1idjA:
undetectable		 1s9pB-1idjA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ijd LIGHT-HARVESTING
PROTEIN B-800/820,
ALPHA CHAIN
LIGHT-HARVESTING
PROTEIN B-800/820,
BETA CHAIN

(Rhodoblastus
acidophilus) 		PF00556
(LHC) 		3 LEU A  16
HIS B  13
ILE A   6
 None
 0.62A 1s9pB-1ijdA:
undetectable		 1s9pB-1ijdA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1izo CYTOCHROME P450
152A1

(Bacillus
subtilis) 		PF00067
(p450) 		3 LEU A 100
HIS A  92
ILE A  84
 None
HEM  A 501 (-3.9A)
HEM  A 501 (-4.3A)
 0.63A 1s9pB-1izoA:
0.0		 1s9pB-1izoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jru P47 PROTEIN

(Rattus
norvegicus) 		PF00789
(UBX) 		3 LEU A 361
HIS A 316
ILE A 318
 None
 0.69A 1s9pB-1jruA:
undetectable		 1s9pB-1jruA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1js8 HEMOCYANIN

(Enteroctopus
dofleini) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		3 LEU A2655
HIS A2785
ILE A2789
 None
 0.47A 1s9pB-1js8A:
undetectable		 1s9pB-1js8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		3 LEU A 231
HIS A 221
ILE A 217
 None
 0.64A 1s9pB-1lnzA:
0.0		 1s9pB-1lnzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nkz LIGHT-HARVESTING
PROTEIN B-800/850,
ALPHA CHAIN
LIGHT-HARVESTING
PROTEIN B-800/850,
BETA CHAIN

(Rhodoblastus
acidophilus) 		PF00556
(LHC) 		3 LEU A  19
HIS B  12
ILE A   6
 None
CXM  A   1 ( 4.0A)
BCL  A 307 ( 4.1A)
 0.62A 1s9pB-1nkzA:
undetectable		 1s9pB-1nkzA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p31 UDP-N-ACETYLMURAMATE
--ALANINE LIGASE

(Haemophilus
influenzae) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		3 LEU A 145
HIS A 119
ILE A 121
 None
 0.61A 1s9pB-1p31A:
0.5		 1s9pB-1p31A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvj PYROGENIC EXOTOXIN B

(Streptococcus
pyogenes) 		PF01640
(Peptidase_C10)
PF13734
(Inhibitor_I69) 		3 LEU A 152
HIS A 204
ILE A 200
 None
 0.55A 1s9pB-1pvjA:
0.0		 1s9pB-1pvjA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vjv UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 6

(Saccharomyces
cerevisiae) 		PF00443
(UCH) 		3 LEU A 188
HIS A 157
ILE A 156
 None
 0.68A 1s9pB-1vjvA:
0.0		 1s9pB-1vjvA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w27 PHENYLALANINE
AMMONIA-LYASE 1

(Petroselinum
crispum) 		PF00221
(Lyase_aromatic) 		3 LEU A 308
HIS A 303
ILE A 315
 None
 0.55A 1s9pB-1w27A:
0.0		 1s9pB-1w27A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1we1 HEME OXYGENASE 1

(Synechocystis
sp. PCC 6803) 		PF01126
(Heme_oxygenase) 		3 LEU A 120
HIS A  63
ILE A  65
 None
 0.69A 1s9pB-1we1A:
0.0		 1s9pB-1we1A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wvt HYPOTHETICAL PROTEIN
ST2180

(Sulfurisphaera
tokodaii) 		PF01923
(Cob_adeno_trans) 		3 LEU A 112
HIS A 106
ILE A 107
 None
 0.56A 1s9pB-1wvtA:
undetectable		 1s9pB-1wvtA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z5v TUBULIN GAMMA-1
CHAIN

(Homo sapiens) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		3 LEU A 205
HIS A 139
ILE A 141
 None
 0.49A 1s9pB-1z5vA:
undetectable		 1s9pB-1z5vA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dg8 PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATORY PROTEIN

(Streptomyces
coelicolor) 		PF00440
(TetR_N) 		3 LEU A 106
HIS A  67
ILE A  68
 None
 0.69A 1s9pB-2dg8A:
undetectable		 1s9pB-2dg8A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7z ACETYLENE HYDRATASE
AHY

(Pelobacter
acetylenicus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 LEU A 122
HIS A 385
ILE A 337
 None
 0.66A 1s9pB-2e7zA:
undetectable		 1s9pB-2e7zA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f00 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE

(Escherichia
coli) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		3 LEU A 146
HIS A 120
ILE A 122
 None
 0.59A 1s9pB-2f00A:
undetectable		 1s9pB-2f00A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2guz MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM14

(Saccharomyces
cerevisiae) 		no annotation 3 LEU A 138
HIS A 133
ILE A 154
 None
 0.70A 1s9pB-2guzA:
undetectable		 1s9pB-2guzA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5g ALR4455 PROTEIN

(Nostoc sp. PCC
7120) 		PF00378
(ECH_1) 		3 LEU D 240
HIS D 144
ILE D 149
 None
 0.69A 1s9pB-2j5gD:
undetectable		 1s9pB-2j5gD:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyy IONOTROPIC GLUTAMATE
RECEPTOR BACTERIAL
HOMOLOGUE

(Nostoc
punctiforme) 		PF00497
(SBP_bac_3) 		3 LEU A  90
HIS A 128
ILE A 105
 None
 0.58A 1s9pB-2pyyA:
undetectable		 1s9pB-2pyyA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qkb RIBONUCLEASE H1

(Homo sapiens) 		PF00075
(RNase_H) 		3 LEU A 250
HIS A 188
ILE A 187
 None
 0.56A 1s9pB-2qkbA:
undetectable		 1s9pB-2qkbA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uu7 GLUTAMINE SYNTHETASE

(Canis lupus) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		3 LEU A 184
HIS A 179
ILE A 224
 None
 0.72A 1s9pB-2uu7A:
undetectable		 1s9pB-2uu7A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uyg 3-DEHYDROQUINATE
DEHYDRATASE

(Thermus
thermophilus) 		PF01220
(DHquinase_II) 		3 LEU A  72
HIS A  99
ILE A 122
 None
GOL  A1143 (-4.1A)
None
 0.69A 1s9pB-2uygA:
undetectable		 1s9pB-2uygA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bws PROTEIN LP49

(Leptospira
interrogans) 		PF10282
(Lactonase) 		3 LEU A 283
HIS A 330
ILE A 239
 None
 0.61A 1s9pB-3bwsA:
undetectable		 1s9pB-3bwsA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dbx CD1-2 ANTIGEN

(Gallus gallus) 		PF07654
(C1-set)
PF16497
(MHC_I_3) 		3 LEU A  20
HIS A  85
ILE A  81
 None
 0.71A 1s9pB-3dbxA:
undetectable		 1s9pB-3dbxA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dm0 MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH RACK1

(Arabidopsis
thaliana;
Escherichia
coli) 		PF00400
(WD40)
PF01547
(SBP_bac_1) 		3 LEU A1186
HIS A1149
ILE A1129
 None
 0.67A 1s9pB-3dm0A:
undetectable		 1s9pB-3dm0A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dty OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY

(Pseudomonas
syringae group
genomosp. 3) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		3 LEU A 336
HIS A  29
ILE A  28
 None
 0.58A 1s9pB-3dtyA:
undetectable		 1s9pB-3dtyA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eag UDP-N-ACETYLMURAMATE
:L-ALANYL-GAMMA-D-GL
UTAMYL-MESO-DIAMINOP
IMELATE LIGASE

(Neisseria
meningitidis) 		PF01225
(Mur_ligase)
PF08245
(Mur_ligase_M) 		3 LEU A  88
HIS A   5
ILE A   7
 None
 0.61A 1s9pB-3eagA:
undetectable		 1s9pB-3eagA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fha ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE

(Glutamicibacter
protophormiae) 		PF03644
(Glyco_hydro_85) 		3 LEU A 121
HIS A 114
ILE A 110
 None
 0.67A 1s9pB-3fhaA:
undetectable		 1s9pB-3fhaA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gem SHORT CHAIN
DEHYDROGENASE

(Pseudomonas
savastanoi) 		PF13561
(adh_short_C2) 		3 LEU A  78
HIS A  83
ILE A 130
 None
 0.68A 1s9pB-3gemA:
undetectable		 1s9pB-3gemA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hje 704AA LONG
HYPOTHETICAL
GLYCOSYLTRANSFERASE

(Sulfurisphaera
tokodaii) 		PF00128
(Alpha-amylase)
PF09196
(DUF1953) 		3 LEU A 432
HIS A  31
ILE A  81
 None
 0.63A 1s9pB-3hjeA:
undetectable		 1s9pB-3hjeA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hym CELL DIVISION CYCLE
PROTEIN 16 HOMOLOG

(Homo sapiens) 		PF13424
(TPR_12) 		3 LEU B 372
HIS B 342
ILE B 338
 None
 0.71A 1s9pB-3hymB:
undetectable		 1s9pB-3hymB:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i1j OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY

(Pseudomonas
syringae group
genomosp. 3) 		PF00106
(adh_short) 		3 LEU A  17
HIS A  99
ILE A 148
 None
 0.59A 1s9pB-3i1jA:
undetectable		 1s9pB-3i1jA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6s SUBTILISIN-LIKE
PROTEASE

(Solanum
lycopersicum) 		PF00082
(Peptidase_S8) 		3 LEU A 527
HIS A 233
ILE A 532
 None
 0.52A 1s9pB-3i6sA:
undetectable		 1s9pB-3i6sA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jz3 SENSOR PROTEIN QSEC

(Escherichia
coli) 		PF00512
(HisKA)
PF02518
(HATPase_c) 		3 LEU A 299
HIS A 429
ILE A 425
 None
 0.52A 1s9pB-3jz3A:
undetectable		 1s9pB-3jz3A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgl SULFATE PERMEASE
FAMILY PROTEIN

(Vibrio cholerae) 		PF01740
(STAS) 		3 LEU A 506
HIS A 499
ILE A 495
 None
 0.69A 1s9pB-3mglA:
undetectable		 1s9pB-3mglA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3naf CALCIUM-ACTIVATED
POTASSIUM CHANNEL
SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1

(Homo sapiens) 		PF03493
(BK_channel_a) 		3 LEU A 387
HIS A 379
ILE A 381
 None
 0.68A 1s9pB-3nafA:
undetectable		 1s9pB-3nafA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ofl L1

(Alphapapillomavirus
7) 		PF00500
(Late_protein_L1) 		3 LEU A 213
HIS A 168
ILE A 228
 None
 0.57A 1s9pB-3oflA:
undetectable		 1s9pB-3oflA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmk NUCLEOCAPSID PROTEIN

(Recombinant
vesicular
stomatitis
Indiana virus
rVSV-G/GFP) 		PF00945
(Rhabdo_ncap) 		3 LEU A 306
HIS A 233
ILE A 237
 None
 0.54A 1s9pB-3pmkA:
undetectable		 1s9pB-3pmkA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)

(Trypanosoma
brucei) 		PF00085
(Thioredoxin)
PF04777
(Evr1_Alr) 		3 LEU A  95
HIS A 184
ILE A 181
 None
 0.66A 1s9pB-3qd9A:
undetectable		 1s9pB-3qd9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rde ARACHIDONATE
12-LIPOXYGENASE,
12S-TYPE

(Sus scrofa) 		PF00305
(Lipoxygenase) 		3 LEU A 408
HIS A 366
ILE A 400
 OYP  A 664 (-3.7A)
FE2  A   1 ( 3.4A)
OYP  A 664 ( 4.6A)
 0.55A 1s9pB-3rdeA:
undetectable		 1s9pB-3rdeA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rxy NIF3 PROTEIN

(Sphaerobacter
thermophilus) 		no annotation 3 LEU A 252
HIS A 247
ILE A 224
 None
 0.70A 1s9pB-3rxyA:
undetectable		 1s9pB-3rxyA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swo GLUTARYL-COA
DEHYDROGENASE

(Mycolicibacterium
smegmatis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 LEU A 330
HIS A 313
ILE A 317
 None
 0.71A 1s9pB-3swoA:
1.4		 1s9pB-3swoA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ue9 ADENYLOSUCCINATE
SYNTHETASE

(Burkholderia
thailandensis) 		PF00709
(Adenylsucc_synt) 		3 LEU A 117
HIS A 178
ILE A 123
 None
 0.59A 1s9pB-3ue9A:
undetectable		 1s9pB-3ue9A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufa SERINE PROTEASE SPLA

(Staphylococcus
aureus) 		PF00089
(Trypsin) 		3 LEU A 169
HIS A  39
ILE A  40
 VPF  A 201 (-4.3A)
VPF  A 201 (-3.8A)
None
 0.68A 1s9pB-3ufaA:
undetectable		 1s9pB-3ufaA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v98 ARACHIDONATE
5-LIPOXYGENASE

(Homo sapiens) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 LEU A 414
HIS A 372
ILE A 406
 None
FE2  A 701 (-3.3A)
None
 0.52A 1s9pB-3v98A:
undetectable		 1s9pB-3v98A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vtr N-ACETYLGLUCOSAMINID
ASE

(Ostrinia
furnacalis) 		PF00728
(Glyco_hydro_20)
PF14845
(Glycohydro_20b2) 		3 LEU A  65
HIS A 565
ILE A 566
 None
 0.63A 1s9pB-3vtrA:
undetectable		 1s9pB-3vtrA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zcw KINESIN-LIKE PROTEIN
KIF11

(Homo sapiens) 		PF00225
(Kinesin) 		3 LEU A 341
HIS A  38
ILE A  40
 None
 0.70A 1s9pB-3zcwA:
undetectable		 1s9pB-3zcwA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2w RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		3 LEU A 114
HIS A 545
ILE A 541
 None
 0.63A 1s9pB-4a2wA:
undetectable		 1s9pB-4a2wA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0s DEAMIDASE-DEPUPYLASE
DOP

(Acidothermus
cellulolyticus) 		PF03136
(Pup_ligase) 		3 LEU A 215
HIS A 241
ILE A 243
 None
MG  A1502 (-3.7A)
None
 0.51A 1s9pB-4b0sA:
undetectable		 1s9pB-4b0sA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0z 26S PROTEASOME
REGULATORY SUBUNIT
RPN12

(Schizosaccharomyces
pombe) 		PF10075
(CSN8_PSD8_EIF3K) 		3 LEU A  99
HIS A 112
ILE A 108
 None
 0.71A 1s9pB-4b0zA:
undetectable		 1s9pB-4b0zA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b6v EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4E
TYPE 3

(Mus musculus) 		PF01652
(IF4E) 		3 LEU A 180
HIS A 183
ILE A 184
 None
 0.63A 1s9pB-4b6vA:
undetectable		 1s9pB-4b6vA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1n CARBON MONOXIDE
DEHYDROGENASE
CORRINOID/IRON-SULFU
R PROTEIN, GAMMA
SUBUNIT
CO
DEHYDROGENASE/ACETYL
-COA SYNTHASE,
IRON-SULFUR PROTEIN

(Carboxydothermus
hydrogenoformans) 		PF03599
(CdhD)
PF04060
(FeS) 		3 LEU B 309
HIS B 304
ILE A 237
 None
 0.47A 1s9pB-4c1nB:
undetectable		 1s9pB-4c1nB:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f6o METACASPASE-1

(Saccharomyces
cerevisiae) 		PF00656
(Peptidase_C14) 		3 LEU A 284
HIS A 422
ILE A 424
 None
 0.61A 1s9pB-4f6oA:
undetectable		 1s9pB-4f6oA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hv4 UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE

(Yersinia pestis) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		3 LEU A 146
HIS A 120
ILE A 122
 None
 0.54A 1s9pB-4hv4A:
undetectable		 1s9pB-4hv4A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4is4 GLUTAMINE SYNTHETASE

(Medicago
truncatula) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		3 LEU A 180
HIS A 175
ILE A 220
 None
 0.71A 1s9pB-4is4A:
undetectable		 1s9pB-4is4A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jp0 43.8 KDA
INSECTICIDAL CRYSTAL
PROTEIN

(Bacillus
thuringiensis) 		PF05431
(Toxin_10) 		3 LEU A 354
HIS A 359
ILE A 367
 None
 0.66A 1s9pB-4jp0A:
undetectable		 1s9pB-4jp0A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jrm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Vibrio cholerae) 		no annotation 3 LEU D 168
HIS D 173
ILE D 160
 None
 0.72A 1s9pB-4jrmD:
undetectable		 1s9pB-4jrmD:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lry PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
DIHYDROXYACETONE-BIN
DING SUBUNIT DHAK

(Escherichia
coli) 		PF02733
(Dak1) 		3 LEU A 323
HIS A 218
ILE A 217
 None
GOL  A 401 (-3.2A)
None
 0.62A 1s9pB-4lryA:
undetectable		 1s9pB-4lryA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4me4 METAL DEPENDENT
PHOSPHOHYDROLASE

(Persephonella
marina) 		PF01590
(GAF)
PF01966
(HD) 		3 LEU A 213
HIS A 168
ILE A 172
 None
 0.69A 1s9pB-4me4A:
undetectable		 1s9pB-4me4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mhl INTERLEUKIN-11

(Homo sapiens) 		PF07400
(IL11) 		3 LEU A 122
HIS A 175
ILE A 171
 None
ARF  A 203 (-4.4A)
ARF  A 203 (-4.5A)
 0.69A 1s9pB-4mhlA:
undetectable		 1s9pB-4mhlA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n5c CARGO-TRANSPORT
PROTEIN YPP1

(Saccharomyces
cerevisiae) 		no annotation 3 LEU A 100
HIS A 123
ILE A 127
 None
 0.42A 1s9pB-4n5cA:
undetectable		 1s9pB-4n5cA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qg5 PUTATIVE
PHOSPHOGLUCOMUTASE

(Leishmania
major) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 LEU A  88
HIS A 170
ILE A 169
 None
 0.49A 1s9pB-4qg5A:
undetectable		 1s9pB-4qg5A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmf KRR1 SMALL SUBUNIT
PROCESSOME COMPONENT

(Saccharomyces
cerevisiae) 		no annotation 3 LEU D 100
HIS D  67
ILE D  93
 None
 0.66A 1s9pB-4qmfD:
undetectable		 1s9pB-4qmfD:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u0t ADC-7 BETA-LACTAMASE

(Acinetobacter
baumannii) 		PF00144
(Beta-lactamase) 		3 LEU A  68
HIS A 256
ILE A 252
 None
 0.34A 1s9pB-4u0tA:
undetectable		 1s9pB-4u0tA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ueg GLYCOGENIN-2

(Homo sapiens) 		PF01501
(Glyco_transf_8) 		3 LEU A 145
HIS A  90
ILE A  72
 None
 0.71A 1s9pB-4uegA:
undetectable		 1s9pB-4uegA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w6v DI-/TRIPEPTIDE
TRANSPORTER

(Yersinia
enterocolitica) 		PF00854
(PTR2) 		3 LEU A 122
HIS A 104
ILE A 100
 None
 0.56A 1s9pB-4w6vA:
undetectable		 1s9pB-4w6vA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wjv RIBOSOME ASSEMBLY
PROTEIN 4

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		3 LEU A 478
HIS A 443
ILE A 426
 None
 0.69A 1s9pB-4wjvA:
undetectable		 1s9pB-4wjvA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxx DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Homo sapiens) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD) 		3 LEU A1565
HIS A1573
ILE A1569
 None
 0.67A 1s9pB-4wxxA:
undetectable		 1s9pB-4wxxA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yk6 ADENOMATOUS
POLYPOSIS COLI
PROTEIN

(Homo sapiens) 		PF00514
(Arm)
PF16629
(Arm_APC_u3) 		3 LEU A 639
HIS A 668
ILE A 632
 None
 0.70A 1s9pB-4yk6A:
undetectable		 1s9pB-4yk6A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bmo PUTATIVE
UNCHARACTERIZED
PROTEIN LNMX

(Streptomyces
atroolivaceus) 		PF02585
(PIG-L) 		3 LEU A 140
HIS A 122
ILE A 173
 None
 0.58A 1s9pB-5bmoA:
undetectable		 1s9pB-5bmoA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d8g TRYPTOPHANASE

(Escherichia
coli) 		PF01212
(Beta_elim_lyase) 		3 LEU A 367
HIS A 370
ILE A 371
 None
 0.58A 1s9pB-5d8gA:
undetectable		 1s9pB-5d8gA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ee7 GLUCAGON
RECEPTOR,ENDOLYSIN,G
LUCAGON RECEPTOR

(Escherichia
virus T4;
Homo sapiens) 		PF00002
(7tm_2)
PF00959
(Phage_lysozyme) 		3 LEU A 242
HIS A 177
ILE A 176
 None
 0.66A 1s9pB-5ee7A:
undetectable		 1s9pB-5ee7A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fgu GREEN FLUORESCENT
PROTEIN,EXTRACELLULA
R STREPTODORNASE D

(Aequorea
victoria;
Streptococcus
pyogenes) 		PF01353
(GFP)
PF13930
(Endonuclea_NS_2) 		3 LEU A1263
HIS A1239
ILE A1111
 None
 0.54A 1s9pB-5fguA:
undetectable		 1s9pB-5fguA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fgw EXTRACELLULAR
STREPTODORNASE D

(Streptococcus
pyogenes) 		PF01223
(Endonuclease_NS) 		3 LEU A 263
HIS A 239
ILE A 111
 None
ZN  A 308 (-3.2A)
None
 0.57A 1s9pB-5fgwA:
undetectable		 1s9pB-5fgwA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsw RNA DEPENDENT RNA
POLYMERASE QDE-1

(Thielavia
terrestris) 		PF05183
(RdRP) 		3 LEU A 416
HIS A 783
ILE A 784
 None
 0.67A 1s9pB-5fswA:
undetectable		 1s9pB-5fswA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN

(Collinsella
aerofaciens) 		PF00106
(adh_short) 		3 LEU A  12
HIS A 125
ILE A 129
 None
 0.49A 1s9pB-5fydA:
undetectable		 1s9pB-5fydA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE

(Pyrococcus
horikoshii) 		PF02449
(Glyco_hydro_42) 		3 LEU A 294
HIS A 252
ILE A 255
 None
 0.62A 1s9pB-5gslA:
undetectable		 1s9pB-5gslA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ham RICKCE

(Rickettsia
bellii) 		no annotation 3 LEU A 435
HIS A 663
ILE A 666
 None
 0.68A 1s9pB-5hamA:
undetectable		 1s9pB-5hamA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ho1 MAGNETOSOME PROTEIN
MAMB

(Magnetospira
sp. QH-2) 		PF16916
(ZT_dimer) 		3 LEU A 256
HIS A 230
ILE A 291
 None
 0.47A 1s9pB-5ho1A:
undetectable		 1s9pB-5ho1A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlc 50S RIBOSOMAL
PROTEIN L13,
CHLOROPLASTIC

(Spinacia
oleracea) 		PF00572
(Ribosomal_L13) 		3 LEU L 140
HIS L 134
ILE L 133
 None
 0.68A 1s9pB-5mlcL:
undetectable		 1s9pB-5mlcL:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1s SEPARIN

(Saccharomyces
cerevisiae) 		PF03568
(Peptidase_C50) 		3 LEU A1060
HIS A 970
ILE A 966
 None
 0.63A 1s9pB-5u1sA:
undetectable		 1s9pB-5u1sA:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vew GLUCAGON-LIKE
PEPTIDE 1
RECEPTOR,ENDOLYSIN
CHIMERA

(Escherichia
virus T4;
Homo sapiens) 		PF00002
(7tm_2)
PF00959
(Phage_lysozyme) 		3 LEU A 244
HIS A 180
ILE A 179
 None
 0.60A 1s9pB-5vewA:
undetectable		 1s9pB-5vewA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vvw UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE

(Pseudomonas
aeruginosa) 		PF01225
(Mur_ligase)
PF08245
(Mur_ligase_M) 		3 LEU A 142
HIS A 116
ILE A 118
 None
 0.62A 1s9pB-5vvwA:
undetectable		 1s9pB-5vvwA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wk0 DAMAGE-INDUCIBLE
PROTEIN DINB

(Staphylococcus
sp. HMSC055H04) 		no annotation 3 LEU A 138
HIS A  47
ILE A  51
 None
NI  A 201 (-3.3A)
None
 0.71A 1s9pB-5wk0A:
undetectable		 1s9pB-5wk0A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ws4 MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Acinetobacter
baumannii) 		no annotation 3 LEU A 507
HIS A 512
ILE A 517
 None
 0.60A 1s9pB-5ws4A:
2.0		 1s9pB-5ws4A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xez GLUCAGON
RECEPTOR,ENDOLYSIN,G
LUCAGON RECEPTOR

(Escherichia
virus T4;
Homo sapiens) 		PF00002
(7tm_2)
PF00959
(Phage_lysozyme)
PF02793
(HRM) 		3 LEU A 242
HIS A 177
ILE A 176
 None
 0.59A 1s9pB-5xezA:
undetectable		 1s9pB-5xezA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yf0 -

(-) 		no annotation 3 LEU A 235
HIS A  65
ILE A  69
 None
 0.56A 1s9pB-5yf0A:
undetectable		 1s9pB-5yf0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER

(Roseiflexus
castenholzii) 		no annotation 3 LEU L 226
HIS L 264
ILE L 263
 None
FE  L1005 (-4.4A)
MQE  L1004 ( 4.5A)
 0.60A 1s9pB-5yq7L:
undetectable		 1s9pB-5yq7L:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6at7 PHENYLALANINE
AMMONIA-LYASE

(Sorghum bicolor) 		no annotation 3 LEU A 295
HIS A 290
ILE A 302
 None
 0.54A 1s9pB-6at7A:
undetectable		 1s9pB-6at7A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6baq BPI FOLD-CONTAINING
FAMILY A MEMBER 1

(Mus musculus) 		no annotation 3 LEU A 267
HIS A 262
ILE A 197
 None
 0.70A 1s9pB-6baqA:
undetectable		 1s9pB-6baqA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bc5 AAC 3-VI PROTEIN

(Enterobacter
cloacae) 		no annotation 3 LEU A  75
HIS A  44
ILE A 175
 None
COA  A 301 (-3.8A)
None
 0.63A 1s9pB-6bc5A:
undetectable		 1s9pB-6bc5A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bsp MAJOR CAPSID PROTEIN
L1

(Alphapapillomavirus
9) 		no annotation 3 LEU C 213
HIS C 168
ILE C 228
 None
 0.67A 1s9pB-6bspC:
undetectable		 1s9pB-6bspC:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Cyanidioschyzon
merolae) 		no annotation 3 LEU A 359
HIS A 390
ILE A 393
 CLA  A1117 ( 4.7A)
CLA  A1127 (-4.0A)
CLA  A1127 (-4.3A)
 0.72A 1s9pB-6fosA:
undetectable		 1s9pB-6fosA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Cyanidioschyzon
merolae) 		no annotation 3 LEU B 180
HIS B 275
ILE B 278
 CLA  B1210 (-3.6A)
CLA  B1215 (-4.0A)
CLA  B1215 ( 4.9A)
 0.69A 1s9pB-6fosB:
undetectable		 1s9pB-6fosB:
18.75