SIMILAR PATTERNS OF AMINO ACIDS FOR 1RXC_F_URFF2001

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cqq TYPE 2 RHINOVIRUS 3C
PROTEASE


(Rhinovirus A)
PF00548
(Peptidase_C3)
4 GLY A  27
ILE A 160
VAL A  37
PRO A  38
None
1.07A 1rxcF-1cqqA:
undetectable
1rxcF-1cqqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fvf SEC1

(Doryteuthis
pealeii)
PF00995
(Sec1)
4 GLY A 445
ARG A 189
ILE A 457
PRO A 458
None
1.05A 1rxcF-1fvfA:
undetectable
1rxcF-1fvfA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g0y INTERLEUKIN-1
RECEPTOR, TYPE I


(Homo sapiens)
PF07679
(I-set)
PF13895
(Ig_2)
4 GLY R 121
GLN R 113
ILE R 165
VAL R 166
None
1.03A 1rxcF-1g0yR:
undetectable
1rxcF-1g0yR:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o4s ASPARTATE
AMINOTRANSFERASE


(Thermotoga
maritima)
PF00155
(Aminotran_1_2)
4 GLY A 244
MET A 238
ILE A 267
VAL A  94
None
0.89A 1rxcF-1o4sA:
undetectable
1rxcF-1o4sA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5w AMINE OXIDASE
[FLAVIN-CONTAINING]
A


(Rattus
norvegicus)
PF01593
(Amino_oxidase)
4 GLY A 447
GLN A  74
ILE A  23
VAL A 449
None
FAD  A 652 ( 4.1A)
FAD  A 652 (-4.8A)
None
1.03A 1rxcF-1o5wA:
undetectable
1rxcF-1o5wA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oed ACETYLCHOLINE
RECEPTOR PROTEIN,
DELTA CHAIN


(Torpedo
marmorata)
PF02932
(Neur_chan_memb)
4 GLY C 301
MET C 293
ILE C 303
VAL C 304
None
0.96A 1rxcF-1oedC:
undetectable
1rxcF-1oedC:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p49 STERYL-SULFATASE

(Homo sapiens)
PF00884
(Sulfatase)
PF14707
(Sulfatase_C)
4 GLY A 344
ILE A  39
VAL A 378
PRO A 379
None
0.91A 1rxcF-1p49A:
undetectable
1rxcF-1p49A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE


(Leishmania
mexicana)
PF00342
(PGI)
4 GLN A 406
ILE A 332
VAL A 328
PRO A 211
None
0.88A 1rxcF-1q50A:
2.7
1rxcF-1q50A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu7 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN I


(Escherichia
coli)
PF00015
(MCPsignal)
4 GLY A 370
GLN A 374
ILE A 368
VAL A 367
None
1.07A 1rxcF-1qu7A:
undetectable
1rxcF-1qu7A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6m RIBONUCLEASE PH

(Pseudomonas
aeruginosa)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
4 GLY A 133
GLN A 233
MET A 159
VAL A  29
None
1.08A 1rxcF-1r6mA:
undetectable
1rxcF-1r6mA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sy7 CATALASE 1

(Neurospora
crassa)
PF00199
(Catalase)
PF01965
(DJ-1_PfpI)
PF06628
(Catalase-rel)
4 ARG A 224
MET A 474
ILE A 323
PRO A 168
None
0.93A 1rxcF-1sy7A:
undetectable
1rxcF-1sy7A:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0i YLR011WP

(Saccharomyces
cerevisiae)
PF03358
(FMN_red)
4 GLY A 126
GLN A  94
ILE A 155
VAL A 157
FMN  A 200 (-3.7A)
FMN  A 200 (-3.9A)
None
FMN  A 200 (-4.4A)
1.05A 1rxcF-1t0iA:
2.3
1rxcF-1t0iA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u08 HYPOTHETICAL
AMINOTRANSFERASE
YBDL


(Escherichia
coli)
PF00155
(Aminotran_1_2)
4 GLY A 346
GLN A 385
ILE A  33
VAL A 347
None
1.08A 1rxcF-1u08A:
undetectable
1rxcF-1u08A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uou THYMIDINE
PHOSPHORYLASE


(Homo sapiens)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C)
4 GLY A 186
ARG A 146
ILE A 167
VAL A 166
None
1.07A 1rxcF-1uouA:
undetectable
1rxcF-1uouA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1us4 PUTATIVE GLUR0
LIGAND BINDING CORE


(Thermus
thermophilus)
PF16868
(NMT1_3)
4 GLY A 172
GLN A 174
ILE A 165
VAL A 167
None
1.02A 1rxcF-1us4A:
undetectable
1rxcF-1us4A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wol 122AA LONG CONSERVED
HYPOTHETICAL PROTEIN


(Sulfurisphaera
tokodaii)
PF05168
(HEPN)
4 GLY A  44
GLN A  49
ILE A   8
VAL A   4
None
1.06A 1rxcF-1wolA:
undetectable
1rxcF-1wolA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr6 GENOME POLYPROTEIN

(Rhinovirus A)
PF00680
(RdRP_1)
4 GLY A 207
GLN A  84
ARG A 305
ILE A 323
None
1.08A 1rxcF-1xr6A:
undetectable
1rxcF-1xr6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayn UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14


(Homo sapiens)
PF00443
(UCH)
4 GLY A 105
GLN A 120
ILE A 169
PRO A 171
None
1.08A 1rxcF-2aynA:
undetectable
1rxcF-2aynA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0r POSSIBLE ADENYL
CYCLASE-ASSOCIATED
PROTEIN


(Cryptosporidium
parvum)
PF08603
(CAP_C)
4 GLY A 108
ILE A 128
VAL A 129
PRO A 130
None
0.91A 1rxcF-2b0rA:
undetectable
1rxcF-2b0rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dyy UPF0076 PROTEIN
PH0854


(Pyrococcus
horikoshii)
PF01042
(Ribonuc_L-PSP)
4 GLY A  45
ILE A  42
VAL A  43
PRO A  34
None
1.00A 1rxcF-2dyyA:
undetectable
1rxcF-2dyyA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6k METAL-DEPENDENT
HYDROLASE


(Lactobacillus
plantarum)
PF04909
(Amidohydro_2)
4 GLN A 111
ILE A  70
VAL A  73
PRO A  98
None
0.94A 1rxcF-2f6kA:
undetectable
1rxcF-2f6kA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE


(Sus scrofa)
PF05187
(ETF_QO)
PF13450
(NAD_binding_8)
4 GLY A 293
ILE A 240
VAL A 292
PRO A 303
None
0.94A 1rxcF-2gmhA:
undetectable
1rxcF-2gmhA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gxa REPLICATION PROTEIN
E1


(Deltapapillomavirus
4)
PF00519
(PPV_E1_C)
4 GLN A 374
ARG A 370
ILE A 503
VAL A 511
None
1.01A 1rxcF-2gxaA:
undetectable
1rxcF-2gxaA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ilu ALDEHYDE
DEHYDROGENASE A


(Escherichia
coli)
PF00171
(Aldedh)
4 GLY A  94
GLN A 283
ILE A  90
PRO A 155
None
1.04A 1rxcF-2iluA:
undetectable
1rxcF-2iluA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lc0 PUTATIVE
UNCHARACTERIZED
PROTEIN TB39.8


(Mycobacterium
tuberculosis)
PF12401
(DUF3662)
4 GLY A  29
ILE A  31
VAL A  32
PRO A  33
None
1.02A 1rxcF-2lc0A:
undetectable
1rxcF-2lc0A:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mx6 SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1


(Mus musculus)
PF00595
(PDZ)
4 GLY A 281
MET A 284
ILE A 266
VAL A 267
None
0.97A 1rxcF-2mx6A:
undetectable
1rxcF-2mx6A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o0r RV0858C
(N-SUCCINYLDIAMINOPI
MELATE
AMINOTRANSFERASE)


(Mycobacterium
tuberculosis)
PF00155
(Aminotran_1_2)
4 GLY A  53
GLN A  56
ILE A  50
PRO A 268
None
0.94A 1rxcF-2o0rA:
undetectable
1rxcF-2o0rA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oce HYPOTHETICAL PROTEIN
PA5201


(Pseudomonas
aeruginosa)
PF00575
(S1)
PF09371
(Tex_N)
PF12836
(HHH_3)
PF16921
(Tex_YqgF)
4 GLY A 660
GLN A 643
ILE A 704
VAL A 661
None
0.99A 1rxcF-2oceA:
undetectable
1rxcF-2oceA:
16.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2oxf URIDINE
PHOSPHORYLASE


(Salmonella
enterica)
PF01048
(PNP_UDP_1)
5 GLY A1096
GLN A1166
ARG A1168
MET A1197
VAL A1221
None
0.85A 1rxcF-2oxfA:
43.1
1rxcF-2oxfA:
97.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbi REGULATOR OF
G-PROTEIN SIGNALING
9


(Mus musculus)
PF00610
(DEP)
PF00615
(RGS)
PF00631
(G-gamma)
4 GLY A  74
GLN A  71
ILE A  83
VAL A  78
None
1.06A 1rxcF-2pbiA:
undetectable
1rxcF-2pbiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9p REPLICATION PROTEIN
E1


(Deltapapillomavirus
4)
PF00519
(PPV_E1_C)
4 GLN A 374
ARG A 370
ILE A 503
VAL A 511
None
0.87A 1rxcF-2v9pA:
undetectable
1rxcF-2v9pA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vyc BIODEGRADATIVE
ARGININE
DECARBOXYLASE


(Escherichia
coli)
PF01276
(OKR_DC_1)
PF03709
(OKR_DC_1_N)
PF03711
(OKR_DC_1_C)
4 GLY A 564
ILE A 568
VAL A 569
PRO A 570
None
1.06A 1rxcF-2vycA:
undetectable
1rxcF-2vycA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu8 GLUCOSE-6-PHOSPHATE
ISOMERASE


(Mycobacterium
tuberculosis)
PF00342
(PGI)
4 GLN A 353
ILE A 279
VAL A 275
PRO A 164
None
0.89A 1rxcF-2wu8A:
2.2
1rxcF-2wu8A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhe UNC18

(Monosiga
brevicollis)
PF00995
(Sec1)
4 GLN A 199
ARG A 500
ILE A 211
VAL A 206
None
1.04A 1rxcF-2xheA:
undetectable
1rxcF-2xheA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yg6 PUTRESCINE OXIDASE

(Rhodococcus
erythropolis)
PF01593
(Amino_oxidase)
4 GLY A 435
GLN A  65
ILE A  15
VAL A 437
None
FAD  A 600 ( 4.5A)
None
None
1.08A 1rxcF-2yg6A:
undetectable
1rxcF-2yg6A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z5x AMINE OXIDASE
[FLAVIN-CONTAINING]
A


(Homo sapiens)
PF01593
(Amino_oxidase)
4 GLY A 447
GLN A  74
ILE A  23
VAL A 449
None
FAD  A 600 ( 4.7A)
FAD  A 600 (-4.9A)
None
1.03A 1rxcF-2z5xA:
undetectable
1rxcF-2z5xA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE


(Flavobacterium
sp.)
PF00144
(Beta-lactamase)
4 GLY A 123
ILE A 131
VAL A 126
PRO A 133
None
1.01A 1rxcF-2zm2A:
undetectable
1rxcF-2zm2A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asm RIBONUCLEASE HIII

(Geobacillus
stearothermophilus)
PF01351
(RNase_HII)
PF11858
(DUF3378)
4 GLY A 269
ILE A 271
VAL A 272
PRO A 265
None
0.97A 1rxcF-3asmA:
undetectable
1rxcF-3asmA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bje NUCLEOSIDE
PHOSPHORYLASE,
PUTATIVE


(Trypanosoma
brucei)
PF01048
(PNP_UDP_1)
4 GLY A 142
GLN A 246
ARG A 248
MET A 285
URA  A 501 (-3.4A)
URA  A 501 (-3.0A)
URA  A 501 (-2.9A)
R1P  A 401 ( 3.9A)
0.22A 1rxcF-3bjeA:
31.1
1rxcF-3bjeA:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epj TRNA
ISOPENTENYLTRANSFERA
SE


(Saccharomyces
cerevisiae)
PF01715
(IPPT)
4 GLY A 110
GLN A  49
MET A  74
ILE A  19
None
1.08A 1rxcF-3epjA:
2.8
1rxcF-3epjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3euf URIDINE
PHOSPHORYLASE 1


(Homo sapiens)
PF01048
(PNP_UDP_1)
4 GLY A 143
GLN A 217
ARG A 219
MET A 249
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
0.26A 1rxcF-3eufA:
27.0
1rxcF-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flb RIFR

(Amycolatopsis
mediterranei)
PF00975
(Thioesterase)
4 GLY A  56
GLN A  53
ILE A 170
VAL A 166
None
1.04A 1rxcF-3flbA:
undetectable
1rxcF-3flbA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdo UNCHARACTERIZED
OXIDOREDUCTASE YVAA


(Bacillus
subtilis)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
4 GLY A 237
MET A 209
ILE A 239
VAL A 240
None
0.90A 1rxcF-3gdoA:
undetectable
1rxcF-3gdoA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gpi NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E


(Methylobacillus
flagellatus)
PF13460
(NAD_binding_10)
4 GLY A   8
GLN A  35
ARG A  32
VAL A  69
None
1.08A 1rxcF-3gpiA:
2.1
1rxcF-3gpiA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5q PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE


(Staphylococcus
aureus)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C)
4 GLY A 355
ILE A 247
VAL A  87
PRO A 242
None
1.04A 1rxcF-3h5qA:
3.4
1rxcF-3h5qA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6


(Homo sapiens)
PF00293
(NUDIX)
4 GLY A 145
GLN A 143
ILE A 225
VAL A 146
None
0.98A 1rxcF-3h95A:
undetectable
1rxcF-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kvy URIDINE
PHOSPHORYLASE


(Bos taurus)
PF01048
(PNP_UDP_1)
4 GLY A 142
GLN A 216
ARG A 218
MET A 248
URA  A 312 (-3.3A)
URA  A 312 (-3.3A)
URA  A 312 (-2.9A)
URA  A 312 ( 3.7A)
0.26A 1rxcF-3kvyA:
27.3
1rxcF-3kvyA:
26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3obz PHYTANOYL-COA
DIOXYGENASE
DOMAIN-CONTAINING
PROTEIN 1


(Homo sapiens)
PF05721
(PhyH)
4 GLY A  37
GLN A 258
ILE A  39
VAL A  40
None
1.00A 1rxcF-3obzA:
undetectable
1rxcF-3obzA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odh OKRAI ENDONUCLEASE

(Oceanobacter
kriegii)
PF02923
(BamHI)
4 GLY A 118
ILE A  76
VAL A  74
PRO A  82
None
0.94A 1rxcF-3odhA:
undetectable
1rxcF-3odhA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oga NUCLEOSIDE
TRIPHOSPHATASE NUDI


(Salmonella
enterica)
PF00293
(NUDIX)
4 GLY A  37
ARG A  52
ILE A   6
VAL A   7
None
None
BME  A 142 ( 4.7A)
None
0.92A 1rxcF-3ogaA:
undetectable
1rxcF-3ogaA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3olm E3 UBIQUITIN-PROTEIN
LIGASE RSP5


(Saccharomyces
cerevisiae)
PF00397
(WW)
PF00632
(HECT)
4 GLY A 553
MET A 664
ILE A 688
VAL A 556
None
0.91A 1rxcF-3olmA:
undetectable
1rxcF-3olmA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p0f URIDINE
PHOSPHORYLASE 2


(Homo sapiens)
PF01048
(PNP_UDP_1)
4 GLY A 149
GLN A 223
ARG A 225
MET A 255
BAU  A 400 (-3.5A)
BAU  A 400 (-3.1A)
BAU  A 400 (-2.8A)
BAU  A 400 (-3.9A)
0.19A 1rxcF-3p0fA:
26.8
1rxcF-3p0fA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p6l SUGAR PHOSPHATE
ISOMERASE/EPIMERASE


(Parabacteroides
distasonis)
PF01261
(AP_endonuc_2)
4 GLY A 103
GLN A  37
ILE A 101
VAL A 102
None
CIT  A 303 ( 3.9A)
None
None
1.00A 1rxcF-3p6lA:
undetectable
1rxcF-3p6lA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p94 GDSL-LIKE LIPASE

(Parabacteroides
distasonis)
PF13472
(Lipase_GDSL_2)
4 GLY A  52
GLN A  80
ARG A  88
ILE A 103
None
1.08A 1rxcF-3p94A:
4.7
1rxcF-3p94A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qtd PMBA PROTEIN

(Pseudomonas
aeruginosa)
PF01523
(PmbA_TldD)
4 GLY A   9
GLN A  43
ARG A  61
VAL A  12
None
1.07A 1rxcF-3qtdA:
undetectable
1rxcF-3qtdA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u37 ACETYL-XYLAN
ESTERASE EST2A


(Butyrivibrio
proteoclasticus)
PF13472
(Lipase_GDSL_2)
4 GLY A 146
MET A 172
ILE A 143
PRO A 352
None
0.96A 1rxcF-3u37A:
undetectable
1rxcF-3u37A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u6r ANTIBODY 1:7 (HEAVY
CHAIN)


(Homo sapiens)
no annotation 4 GLY H 113
GLN H  38
ILE H 108
PRO H 105
None
1.08A 1rxcF-3u6rH:
undetectable
1rxcF-3u6rH:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbn PUTATIVE
UNCHARACTERIZED
PROTEIN


(Pyrococcus
furiosus)
PF01554
(MatE)
4 GLY A 108
MET A 115
ILE A 150
VAL A 151
None
None
OLC  A 505 ( 4.4A)
None
0.89A 1rxcF-3wbnA:
undetectable
1rxcF-3wbnA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyx AMINE OXIDASE
[FLAVIN-CONTAINING]
B


(Homo sapiens)
PF01593
(Amino_oxidase)
4 GLY A 438
GLN A  65
ILE A  14
VAL A 440
None
FAD  A 600 ( 4.8A)
FAD  A 600 (-4.8A)
None
1.05A 1rxcF-3zyxA:
undetectable
1rxcF-3zyxA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bej DYNAMIN 1-LIKE
PROTEIN


(Homo sapiens)
PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF02212
(GED)
4 GLY A 240
ILE A 235
VAL A 237
PRO A 236
None
1.08A 1rxcF-4bejA:
undetectable
1rxcF-4bejA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c1l 2-DEHYDRO-3-DEOXYPHO
SPHOHEPTONATE
ALDOLASE


(Pyrococcus
furiosus)
PF00793
(DAHP_synth_1)
4 GLY A  29
GLN A 242
ILE A  39
VAL A  42
None
0.95A 1rxcF-4c1lA:
undetectable
1rxcF-4c1lA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE


(Brucella
melitensis)
no annotation 4 GLN D 349
ILE D 275
VAL D 271
PRO D 161
None
0.89A 1rxcF-4em6D:
3.0
1rxcF-4em6D:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emb 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE


(Borreliella
burgdorferi)
PF00300
(His_Phos_1)
4 GLY A 234
GLN A  50
ILE A 215
PRO A 216
None
0.97A 1rxcF-4embA:
undetectable
1rxcF-4embA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4faj PRGZ

(Enterococcus
faecalis)
PF00496
(SBP_bac_5)
4 GLY A 427
GLN A 431
VAL A 417
PRO A 447
None
0.94A 1rxcF-4fajA:
undetectable
1rxcF-4fajA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grs PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE,
2-DEHYDRO-3-DEOXYPHO
SPHOHEPTONATE
ALDOLASE


(Pyrococcus
furiosus;
Thermotoga
maritima)
PF00793
(DAHP_synth_1)
4 GLY A 100
GLN A 313
ILE A 110
VAL A 113
None
1.04A 1rxcF-4grsA:
undetectable
1rxcF-4grsA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH


(Vibrio
parahaemolyticus)
PF02386
(TrkH)
4 GLY A 346
GLN A 283
ILE A 361
VAL A 358
None
1.01A 1rxcF-4j9uA:
undetectable
1rxcF-4j9uA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jxc FEFE-HYDROGENASE
MATURASE


(Thermotoga
maritima)
PF04055
(Radical_SAM)
PF06968
(BATS)
4 GLY A 226
MET A 271
ILE A 265
VAL A 225
None
1.07A 1rxcF-4jxcA:
undetectable
1rxcF-4jxcA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kg7 PEPTIDASE S8 AND
S53, SUBTILISIN,
KEXIN, SEDOLISIN


(Mycolicibacterium
smegmatis)
PF00082
(Peptidase_S8)
4 GLY A 291
GLN A 375
VAL A 287
PRO A 308
None
0.88A 1rxcF-4kg7A:
2.6
1rxcF-4kg7A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ksa MALONYL-COA
DECARBOXYLASE


(Rhodopseudomonas
palustris)
PF05292
(MCD)
PF17408
(MCD_N)
4 GLY A 438
ARG A 380
ILE A 440
PRO A 381
None
1.06A 1rxcF-4ksaA:
undetectable
1rxcF-4ksaA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4me8 SIGNAL PEPTIDASE I

(Enterococcus
faecalis)
PF00717
(Peptidase_S24)
4 GLY A 163
ILE A  60
VAL A 164
PRO A  54
None
1.02A 1rxcF-4me8A:
undetectable
1rxcF-4me8A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nfy D-3-PHOSPHOGLYCERATE
DEHYDROGENASE,
PUTATIVE


(Entamoeba
histolytica)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
4 GLY A 210
MET A 230
ILE A 184
VAL A 183
None
1.02A 1rxcF-4nfyA:
undetectable
1rxcF-4nfyA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qgs ALCOHOL
DEHYDROGENASE YQHD


(Escherichia
coli)
PF00465
(Fe-ADH)
4 GLY A 270
MET A 276
ILE A 287
VAL A 288
None
0.79A 1rxcF-4qgsA:
undetectable
1rxcF-4qgsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlj BETA-GLUCOSIDASE 7

(Oryza sativa)
PF00232
(Glyco_hydro_1)
4 GLY A 351
ILE A 361
VAL A 362
PRO A 363
None
1.06A 1rxcF-4qljA:
undetectable
1rxcF-4qljA:
20.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r2w URIDINE
PHOSPHORYLASE


(Shewanella
oneidensis)
PF01048
(PNP_UDP_1)
7 GLY A  93
GLN A 163
ARG A 165
MET A 194
ILE A 217
VAL A 218
PRO A 226
None
None
None
GOL  A 303 (-3.5A)
None
None
None
0.21A 1rxcF-4r2wA:
43.6
1rxcF-4r2wA:
75.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r31 URIDINE
PHOSPHORYLASE


(Actinobacillus
succinogenes)
PF01048
(PNP_UDP_1)
5 GLY A  94
GLN A 164
ARG A 166
MET A 195
VAL A 219
None
None
None
GOL  A 301 (-4.0A)
None
0.61A 1rxcF-4r31A:
41.8
1rxcF-4r31A:
66.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r31 URIDINE
PHOSPHORYLASE


(Actinobacillus
succinogenes)
PF01048
(PNP_UDP_1)
5 GLY A  94
GLN A 164
MET A 195
ILE A 218
VAL A 219
None
None
GOL  A 301 (-4.0A)
None
None
0.77A 1rxcF-4r31A:
41.8
1rxcF-4r31A:
66.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4re2 BETA-MANNOSIDASE/BET
A-GLUCOSIDASE


(Oryza sativa)
PF00232
(Glyco_hydro_1)
4 GLY A 354
ILE A 364
VAL A 365
PRO A 366
None
1.06A 1rxcF-4re2A:
undetectable
1rxcF-4re2A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rm4 CYTOCHROME P450

(Bacillus
subtilis)
PF00067
(p450)
4 GLN A 157
ILE A 198
VAL A 150
PRO A 151
None
1.08A 1rxcF-4rm4A:
undetectable
1rxcF-4rm4A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rv3 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE


(Staphylococcus
aureus)
PF00388
(PI-PLC-X)
4 GLY A 284
GLN A  49
ILE A 293
VAL A 294
None
1.05A 1rxcF-4rv3A:
undetectable
1rxcF-4rv3A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u39 CELL DIVISION FACTOR
CELL DIVISION
PROTEIN FTSZ


(Bacillus
subtilis)
PF00091
(Tubulin)
PF12327
(FtsZ_C)
PF13072
(DUF3936)
4 GLY A  37
MET J   6
ILE A  14
VAL A  38
None
0.99A 1rxcF-4u39A:
4.1
1rxcF-4u39A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzb NITROGENASE IRON
PROTEIN 1


(Azotobacter
vinelandii)
PF00142
(Fer4_NifH)
4 GLY E 167
ILE E 168
VAL E 169
PRO E 256
None
1.06A 1rxcF-4wzbE:
undetectable
1rxcF-4wzbE:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpd RNA-DIRECTED RNA
POLYMERASE


(Enterovirus B)
PF00680
(RdRP_1)
4 GLY A 207
GLN A  84
ARG A 307
ILE A 325
None
1.08A 1rxcF-4zpdA:
undetectable
1rxcF-4zpdA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxw C-DOMAIN TYPE II
PEPTIDE SYNTHETASE


(Streptomyces
globisporus)
PF00668
(Condensation)
4 MET A  26
ILE A 365
VAL A 367
PRO A 289
None
None
4T7  A 501 (-4.8A)
None
0.85A 1rxcF-4zxwA:
undetectable
1rxcF-4zxwA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a96 POLYHEDRIN

(Cypovirus 14)
PF17515
(CPV_Polyhedrin)
4 GLY A 176
MET A 173
ILE A 115
VAL A 177
None
1.02A 1rxcF-5a96A:
undetectable
1rxcF-5a96A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bmt UNCHARACTERIZED
PROTEIN


(Parabacteroides
merdae)
no annotation 4 GLY A 207
MET A 213
ILE A 142
VAL A 205
None
1.07A 1rxcF-5bmtA:
undetectable
1rxcF-5bmtA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE


(Bacillus
subtilis)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C)
4 GLY A 355
ILE A 247
VAL A  87
PRO A 242
GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
1.00A 1rxcF-5ep8A:
3.4
1rxcF-5ep8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fim YGAU

(Escherichia
coli)
PF01476
(LysM)
PF04972
(BON)
4 GLY A  11
GLN A 142
MET A 131
ILE A  80
None
1.07A 1rxcF-5fimA:
undetectable
1rxcF-5fimA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2q SERINE/THREONINE-PRO
TEIN KINASE 40


(Homo sapiens)
no annotation 4 GLY C  86
ILE C  49
VAL C  46
PRO C  45
None
0.91A 1rxcF-5l2qC:
undetectable
1rxcF-5l2qC:
21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5lhv URIDINE
PHOSPHORYLASE


(Vibrio cholerae)
PF01048
(PNP_UDP_1)
5 GLY A  95
GLN A 165
ARG A 167
MET A 196
ILE A 219
URI  A 303 ( 3.4A)
URA  A 304 ( 2.9A)
URA  A 304 ( 2.9A)
URI  A 303 ( 3.7A)
None
0.22A 1rxcF-5lhvA:
43.8
1rxcF-5lhvA:
75.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ofu FBP PROTEIN

(Leishmania
major)
PF00316
(FBPase)
4 GLY A 304
ARG A 335
ILE A 306
VAL A 300
None
0.98A 1rxcF-5ofuA:
undetectable
1rxcF-5ofuA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1


(Saccharomyces
cerevisiae)
PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
4 GLY T1681
ARG T1731
ILE T1678
VAL T1677
None
1.00A 1rxcF-5ojsT:
undetectable
1rxcF-5ojsT:
5.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uoh CARBOXYLESTERASE A

(Mycobacterium
tuberculosis)
PF00561
(Abhydrolase_1)
4 GLY A 174
ILE A 178
VAL A 175
PRO A 429
None
0.91A 1rxcF-5uohA:
undetectable
1rxcF-5uohA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wzr ALPHA-N-ACETYLGALACT
OSAMINIDASE


(Bifidobacterium
bifidum)
PF11308
(Glyco_hydro_129)
4 GLY A 509
ARG A 501
ILE A 140
VAL A 138
None
1.06A 1rxcF-5wzrA:
undetectable
1rxcF-5wzrA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnz CRED

(Streptomyces
cremeus)
no annotation 4 GLY A 374
ILE A 376
VAL A 377
PRO A 437
None
1.03A 1rxcF-5xnzA:
undetectable
1rxcF-5xnzA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717


(Pseudoalteromonas
arctica)
no annotation 4 GLY A 372
ARG A 459
VAL A 368
PRO A 389
None
1.05A 1rxcF-5yl7A:
undetectable
1rxcF-5yl7A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bfu SPIKE PROTEIN

(Coronavirus
HKU15)
no annotation 4 GLY A 915
GLN A 582
ILE A 563
PRO A 938
NAG  A1914 ( 4.9A)
None
None
NAG  A1914 ( 4.6A)
0.99A 1rxcF-6bfuA:
undetectable
1rxcF-6bfuA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT C


(Flavobacterium
johnsoniae)
no annotation 4 GLY C 312
GLN C 358
ILE C 310
VAL C 311
None
1.04A 1rxcF-6btmC:
undetectable
1rxcF-6btmC:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MONOVALENT CATION/H+
ANTIPORTER SUBUNIT B
MONOVALENT CATION/H+
ANTIPORTER SUBUNIT F


(Pyrococcus
furiosus)
no annotation 4 GLY F   6
GLN B  80
ILE F   8
VAL F   9
None
1.00A 1rxcF-6cfwF:
undetectable
1rxcF-6cfwF:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dt3 NUCLEOSIDE
TRIPHOSPHATASE NUDI


(Klebsiella
pneumoniae)
no annotation 4 GLY A  37
ARG A  52
ILE A   6
VAL A   7
None
0.92A 1rxcF-6dt3A:
undetectable
1rxcF-6dt3A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6h20 -

(-)
no annotation 4 GLN A 184
ILE A 226
VAL A 205
PRO A 224
None
0.91A 1rxcF-6h20A:
undetectable
1rxcF-6h20A:
undetectable