SIMILAR PATTERNS OF AMINO ACIDS FOR 1RXC_C_URFC2081
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aw1 | TRIOSEPHOSPHATEISOMERASE (Moritellamarina) |
PF00121(TIM) | 4 | GLY A 212GLN A 210MET A 7ILE A 174 | PGA A 290 ( 4.6A)NoneNonePGA A 290 (-4.0A) | 0.95A | 1rxcC-1aw1A:undetectable | 1rxcC-1aw1A:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g0y | INTERLEUKIN-1RECEPTOR, TYPE I (Homo sapiens) |
PF07679(I-set)PF13895(Ig_2) | 4 | GLY R 121GLN R 113ILE R 165VAL R 166 | None | 0.86A | 1rxcC-1g0yR:undetectable | 1rxcC-1g0yR:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o4s | ASPARTATEAMINOTRANSFERASE (Thermotogamaritima) |
PF00155(Aminotran_1_2) | 4 | GLY A 244MET A 238ILE A 267VAL A 94 | None | 0.93A | 1rxcC-1o4sA:undetectable | 1rxcC-1o4sA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oed | ACETYLCHOLINERECEPTOR PROTEIN,DELTA CHAIN (Torpedomarmorata) |
PF02932(Neur_chan_memb) | 4 | GLY C 301MET C 293ILE C 303VAL C 304 | None | 0.88A | 1rxcC-1oedC:undetectable | 1rxcC-1oedC:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofe | FERREDOXIN-DEPENDENTGLUTAMATE SYNTHASE 2 (Synechocystissp. PCC 6803) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 4 | GLY A 341MET A 47ILE A 339PRO A 288 | None | 1.06A | 1rxcC-1ofeA:undetectable | 1rxcC-1ofeA:11.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p49 | STERYL-SULFATASE (Homo sapiens) |
PF00884(Sulfatase)PF14707(Sulfatase_C) | 4 | GLY A 344ILE A 39VAL A 378PRO A 379 | None | 1.00A | 1rxcC-1p49A:undetectable | 1rxcC-1p49A:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q50 | GLUCOSE-6-PHOSPHATEISOMERASE (Leishmaniamexicana) |
PF00342(PGI) | 4 | GLN A 406ILE A 332VAL A 328PRO A 211 | None | 0.90A | 1rxcC-1q50A:2.6 | 1rxcC-1q50A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rdr | POLIOVIRUS 3DPOLYMERASE (Enterovirus C) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 306ILE A 324 | None | 1.05A | 1rxcC-1rdrA:undetectable | 1rxcC-1rdrA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sy7 | CATALASE 1 (Neurosporacrassa) |
PF00199(Catalase)PF01965(DJ-1_PfpI)PF06628(Catalase-rel) | 4 | ARG A 224MET A 474ILE A 323PRO A 168 | None | 0.95A | 1rxcC-1sy7A:undetectable | 1rxcC-1sy7A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uxi | MALATE DEHYDROGENASE (Chloroflexusaurantiacus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLY A 214ARG A 88ILE A 216VAL A 217 | FUM A1311 ( 4.8A)FUM A1311 (-4.0A)NoneNone | 0.88A | 1rxcC-1uxiA:undetectable | 1rxcC-1uxiA:24.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wr8 | PHOSPHOGLYCOLATEPHOSPHATASE (Pyrococcushorikoshii) |
PF08282(Hydrolase_3) | 4 | GLY A 176GLN A 196ILE A 8VAL A 175 | None | 1.01A | 1rxcC-1wr8A:3.4 | 1rxcC-1wr8A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xl3 | PROTEIN TYPE ASECRETION CONTROLPROTEIN (Yersinia pestis) |
PF07201(HrpJ)PF09059(TyeA) | 4 | GLY C 10GLN A 220ILE C 12VAL C 13 | None | 0.93A | 1rxcC-1xl3C:undetectable | 1rxcC-1xl3C:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr6 | GENOME POLYPROTEIN (Rhinovirus A) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 305ILE A 323 | None | 0.99A | 1rxcC-1xr6A:undetectable | 1rxcC-1xr6A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b0r | POSSIBLE ADENYLCYCLASE-ASSOCIATEDPROTEIN (Cryptosporidiumparvum) |
PF08603(CAP_C) | 4 | GLY A 108ILE A 128VAL A 129PRO A 130 | None | 1.02A | 1rxcC-2b0rA:undetectable | 1rxcC-2b0rA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dg6 | PUTATIVETRANSCRIPTIONALREGULATOR (Streptomycescoelicolor) |
PF13411(MerR_1) | 4 | GLY A 57GLN A 192VAL A 59PRO A 90 | None | 0.98A | 1rxcC-2dg6A:undetectable | 1rxcC-2dg6A:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dyy | UPF0076 PROTEINPH0854 (Pyrococcushorikoshii) |
PF01042(Ribonuc_L-PSP) | 4 | GLY A 45ILE A 42VAL A 43PRO A 34 | None | 0.84A | 1rxcC-2dyyA:undetectable | 1rxcC-2dyyA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f6k | METAL-DEPENDENTHYDROLASE (Lactobacillusplantarum) |
PF04909(Amidohydro_2) | 4 | GLN A 111ILE A 70VAL A 73PRO A 98 | None | 1.05A | 1rxcC-2f6kA:undetectable | 1rxcC-2f6kA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gmh | ELECTRON TRANSFERFLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE (Sus scrofa) |
PF05187(ETF_QO)PF13450(NAD_binding_8) | 4 | GLY A 293ILE A 240VAL A 292PRO A 303 | None | 0.99A | 1rxcC-2gmhA:undetectable | 1rxcC-2gmhA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2grv | LPQW (Mycolicibacteriumsmegmatis) |
PF00496(SBP_bac_5) | 4 | GLY A 588GLN A 253VAL A 585PRO A 278 | None | 1.05A | 1rxcC-2grvA:undetectable | 1rxcC-2grvA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hjr | MALATE DEHYDROGENASE (Cryptosporidiumparvum) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLY A 231ARG A 100ILE A 233VAL A 234 | NoneCIT A2001 (-3.9A)NoneNone | 0.97A | 1rxcC-2hjrA:undetectable | 1rxcC-2hjrA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ijd | PICORNAIN 3C,RNA-DIRECTED RNAPOLYMERASE (Enterovirus C) |
PF00548(Peptidase_C3)PF00680(RdRP_1) | 4 | GLY 1 390GLN 1 267ARG 1 489ILE 1 507 | None | 1.03A | 1rxcC-2ijd1:undetectable | 1rxcC-2ijd1:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ilu | ALDEHYDEDEHYDROGENASE A (Escherichiacoli) |
PF00171(Aldedh) | 4 | GLY A 94GLN A 283ILE A 90PRO A 155 | None | 0.96A | 1rxcC-2iluA:2.0 | 1rxcC-2iluA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lc0 | PUTATIVEUNCHARACTERIZEDPROTEIN TB39.8 (Mycobacteriumtuberculosis) |
PF12401(DUF3662) | 4 | GLY A 29ILE A 31VAL A 32PRO A 33 | None | 0.94A | 1rxcC-2lc0A:undetectable | 1rxcC-2lc0A:25.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lfc | FUMARATE REDUCTASE,FLAVOPROTEIN SUBUNIT (Lactobacillusplantarum) |
PF00890(FAD_binding_2) | 4 | GLY A 29GLN A 49ILE A 107VAL A 108 | None | 1.05A | 1rxcC-2lfcA:undetectable | 1rxcC-2lfcA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mx6 | SEGMENT POLARITYPROTEIN DISHEVELLEDHOMOLOG DVL-1 (Mus musculus) |
PF00595(PDZ) | 4 | GLY A 281MET A 284ILE A 266VAL A 267 | None | 1.00A | 1rxcC-2mx6A:undetectable | 1rxcC-2mx6A:16.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oce | HYPOTHETICAL PROTEINPA5201 (Pseudomonasaeruginosa) |
PF00575(S1)PF09371(Tex_N)PF12836(HHH_3)PF16921(Tex_YqgF) | 4 | GLY A 660GLN A 643ILE A 704VAL A 661 | None | 0.98A | 1rxcC-2oceA:undetectable | 1rxcC-2oceA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ofq | TRAO (IncN plasmidR46) |
PF03524(CagX) | 4 | GLY A 263ILE A 255VAL A 262PRO A 197 | None | 1.06A | 1rxcC-2ofqA:undetectable | 1rxcC-2ofqA:14.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oxf | URIDINEPHOSPHORYLASE (Salmonellaenterica) |
PF01048(PNP_UDP_1) | 5 | GLY A1096GLN A1166ARG A1168ILE A1220VAL A1221 | None | 0.86A | 1rxcC-2oxfA:43.3 | 1rxcC-2oxfA:97.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oxf | URIDINEPHOSPHORYLASE (Salmonellaenterica) |
PF01048(PNP_UDP_1) | 5 | GLY A1096GLN A1166ARG A1168MET A1197VAL A1221 | None | 0.65A | 1rxcC-2oxfA:43.3 | 1rxcC-2oxfA:97.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qqp | LARGE CAPSID PROTEIN (Providencevirus) |
PF03566(Peptidase_A21) | 4 | GLY A 549MET A 445ILE A 440VAL A 550 | None | 1.03A | 1rxcC-2qqpA:undetectable | 1rxcC-2qqpA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2raa | PYRUVATE SYNTHASESUBUNIT PORC (Thermotogamaritima) |
PF01558(POR) | 4 | GLY A 19MET A 26ILE A 79PRO A 137 | SO4 A 193 (-3.4A)NoneNoneNone | 1.06A | 1rxcC-2raaA:undetectable | 1rxcC-2raaA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uv7 | 5'-AMP-ACTIVATEDPROTEIN KINASESUBUNIT GAMMA-1 (Homo sapiens) |
PF00571(CBS) | 4 | GLY A 199GLN A 320ILE A 312VAL A 313 | AMP A1324 ( 4.8A)NoneAMP A1324 (-3.7A)None | 1.04A | 1rxcC-2uv7A:undetectable | 1rxcC-2uv7A:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vyc | BIODEGRADATIVEARGININEDECARBOXYLASE (Escherichiacoli) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 4 | GLY A 564ILE A 568VAL A 569PRO A 570 | None | 1.06A | 1rxcC-2vycA:undetectable | 1rxcC-2vycA:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wu8 | GLUCOSE-6-PHOSPHATEISOMERASE (Mycobacteriumtuberculosis) |
PF00342(PGI) | 4 | GLN A 353ILE A 279VAL A 275PRO A 164 | None | 0.91A | 1rxcC-2wu8A:undetectable | 1rxcC-2wu8A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhe | UNC18 (Monosigabrevicollis) |
PF00995(Sec1) | 4 | GLN A 199ARG A 500ILE A 211VAL A 206 | None | 0.96A | 1rxcC-2xheA:undetectable | 1rxcC-2xheA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zm2 | 6-AMINOHEXANOATE-DIMER HYDROLASE (Flavobacteriumsp.) |
PF00144(Beta-lactamase) | 4 | GLY A 123ILE A 131VAL A 126PRO A 133 | None | 1.02A | 1rxcC-2zm2A:undetectable | 1rxcC-2zm2A:25.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bje | NUCLEOSIDEPHOSPHORYLASE,PUTATIVE (Trypanosomabrucei) |
PF01048(PNP_UDP_1) | 4 | GLY A 142GLN A 246ARG A 248MET A 285 | URA A 501 (-3.4A)URA A 501 (-3.0A)URA A 501 (-2.9A)R1P A 401 ( 3.9A) | 0.33A | 1rxcC-3bjeA:5.7 | 1rxcC-3bjeA:25.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3czm | L-LACTATEDEHYDROGENASE (Toxoplasmagondii) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLY A 237ARG A 109ILE A 239VAL A 240 | NoneOXQ A 708 (-4.0A)NoneNone | 0.92A | 1rxcC-3czmA:undetectable | 1rxcC-3czmA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3epj | TRNAISOPENTENYLTRANSFERASE (Saccharomycescerevisiae) |
PF01715(IPPT) | 4 | GLY A 110GLN A 49MET A 74ILE A 19 | None | 1.00A | 1rxcC-3epjA:2.7 | 1rxcC-3epjA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euf | URIDINEPHOSPHORYLASE 1 (Homo sapiens) |
PF01048(PNP_UDP_1) | 4 | GLY A 143GLN A 217ARG A 219MET A 249 | BAU A 400 (-3.3A)BAU A 400 (-3.1A)BAU A 400 (-3.0A)BAU A 400 (-3.8A) | 0.40A | 1rxcC-3eufA:25.9 | 1rxcC-3eufA:27.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdo | UNCHARACTERIZEDOXIDOREDUCTASE YVAA (Bacillussubtilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | GLY A 237MET A 209ILE A 239VAL A 240 | None | 0.97A | 1rxcC-3gdoA:undetectable | 1rxcC-3gdoA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5q | PYRIMIDINE-NUCLEOSIDE PHOSPHORYLASE (Staphylococcusaureus) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | GLY A 355ILE A 247VAL A 87PRO A 242 | None | 0.99A | 1rxcC-3h5qA:3.4 | 1rxcC-3h5qA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h95 | NUCLEOSIDEDIPHOSPHATE-LINKEDMOIETY X MOTIF 6 (Homo sapiens) |
PF00293(NUDIX) | 4 | GLY A 145GLN A 143ILE A 225VAL A 146 | None | 0.95A | 1rxcC-3h95A:undetectable | 1rxcC-3h95A:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kvy | URIDINEPHOSPHORYLASE (Bos taurus) |
PF01048(PNP_UDP_1) | 4 | GLY A 142GLN A 216ARG A 218MET A 248 | URA A 312 (-3.3A)URA A 312 (-3.3A)URA A 312 (-2.9A)URA A 312 ( 3.7A) | 0.41A | 1rxcC-3kvyA:25.9 | 1rxcC-3kvyA:26.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n77 | NUCLEOSIDETRIPHOSPHATASE NUDI (Salmonellaenterica) |
PF00293(NUDIX) | 4 | GLY A 37ARG A 52ILE A 6VAL A 7 | None | 1.00A | 1rxcC-3n77A:undetectable | 1rxcC-3n77A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obz | PHYTANOYL-COADIOXYGENASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF05721(PhyH) | 4 | GLY A 37GLN A 258ILE A 39VAL A 40 | None | 1.07A | 1rxcC-3obzA:undetectable | 1rxcC-3obzA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3odh | OKRAI ENDONUCLEASE (Oceanobacterkriegii) |
PF02923(BamHI) | 4 | GLY A 118ILE A 76VAL A 74PRO A 82 | None | 0.85A | 1rxcC-3odhA:undetectable | 1rxcC-3odhA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oga | NUCLEOSIDETRIPHOSPHATASE NUDI (Salmonellaenterica) |
PF00293(NUDIX) | 4 | GLY A 37ARG A 52ILE A 6VAL A 7 | NoneNoneBME A 142 ( 4.7A)None | 0.79A | 1rxcC-3ogaA:undetectable | 1rxcC-3ogaA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3olm | E3 UBIQUITIN-PROTEINLIGASE RSP5 (Saccharomycescerevisiae) |
PF00397(WW)PF00632(HECT) | 4 | GLY A 553MET A 664ILE A 688VAL A 556 | None | 1.04A | 1rxcC-3olmA:undetectable | 1rxcC-3olmA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3om9 | LACTATEDEHYDROGENASE (Toxoplasmagondii) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLY A 237ARG A 109ILE A 239VAL A 240 | NoneOXQ A 702 (-3.9A)NoneNone | 0.92A | 1rxcC-3om9A:undetectable | 1rxcC-3om9A:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p0f | URIDINEPHOSPHORYLASE 2 (Homo sapiens) |
PF01048(PNP_UDP_1) | 4 | GLY A 149GLN A 223ARG A 225MET A 255 | BAU A 400 (-3.5A)BAU A 400 (-3.1A)BAU A 400 (-2.8A)BAU A 400 (-3.9A) | 0.33A | 1rxcC-3p0fA:25.8 | 1rxcC-3p0fA:28.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p6l | SUGAR PHOSPHATEISOMERASE/EPIMERASE (Parabacteroidesdistasonis) |
PF01261(AP_endonuc_2) | 4 | GLY A 103GLN A 37ILE A 101VAL A 102 | NoneCIT A 303 ( 3.9A)NoneNone | 0.99A | 1rxcC-3p6lA:undetectable | 1rxcC-3p6lA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s47 | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Clostridiumbeijerinckii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLY A 368MET A 97ILE A 362PRO A 352 | None | 1.03A | 1rxcC-3s47A:undetectable | 1rxcC-3s47A:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u37 | ACETYL-XYLANESTERASE EST2A (Butyrivibrioproteoclasticus) |
PF13472(Lipase_GDSL_2) | 4 | GLY A 146MET A 172ILE A 143PRO A 352 | None | 0.91A | 1rxcC-3u37A:2.8 | 1rxcC-3u37A:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbn | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrococcusfuriosus) |
PF01554(MatE) | 4 | GLY A 108MET A 115ILE A 150VAL A 151 | NoneNoneOLC A 505 ( 4.4A)None | 0.90A | 1rxcC-3wbnA:undetectable | 1rxcC-3wbnA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zth | STU0660 (Streptococcusthermophilus) |
PF16813(Cas_St_Csn2) | 4 | GLY A 25MET A 304ILE A 256VAL A 24 | None | 1.05A | 1rxcC-3zthA:undetectable | 1rxcC-3zthA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1l | 2-DEHYDRO-3-DEOXYPHOSPHOHEPTONATEALDOLASE (Pyrococcusfuriosus) |
PF00793(DAHP_synth_1) | 4 | GLY A 29GLN A 242ILE A 39VAL A 42 | None | 1.06A | 1rxcC-4c1lA:undetectable | 1rxcC-4c1lA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eew | LARGE PROLINE-RICHPROTEIN BAG6 (Homo sapiens) |
PF00240(ubiquitin) | 4 | GLY A 34GLN A 73ILE A 32VAL A 33 | None | 1.05A | 1rxcC-4eewA:undetectable | 1rxcC-4eewA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4em6 | GLUCOSE-6-PHOSPHATEISOMERASE (Brucellamelitensis) |
no annotation | 4 | GLN D 349ILE D 275VAL D 271PRO D 161 | None | 0.90A | 1rxcC-4em6D:undetectable | 1rxcC-4em6D:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4emb | 2,3-BISPHOSPHOGLYCERATE-DEPENDENTPHOSPHOGLYCERATEMUTASE (Borreliellaburgdorferi) |
PF00300(His_Phos_1) | 4 | GLY A 234GLN A 50ILE A 215PRO A 216 | None | 1.05A | 1rxcC-4embA:undetectable | 1rxcC-4embA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4faj | PRGZ (Enterococcusfaecalis) |
PF00496(SBP_bac_5) | 4 | GLY A 427GLN A 431VAL A 417PRO A 447 | None | 1.03A | 1rxcC-4fajA:undetectable | 1rxcC-4fajA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jxc | FEFE-HYDROGENASEMATURASE (Thermotogamaritima) |
PF04055(Radical_SAM)PF06968(BATS) | 4 | GLY A 226MET A 271ILE A 265VAL A 225 | None | 1.05A | 1rxcC-4jxcA:undetectable | 1rxcC-4jxcA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kg7 | PEPTIDASE S8 ANDS53, SUBTILISIN,KEXIN, SEDOLISIN (Mycolicibacteriumsmegmatis) |
PF00082(Peptidase_S8) | 4 | GLY A 291GLN A 375VAL A 287PRO A 308 | None | 0.98A | 1rxcC-4kg7A:2.7 | 1rxcC-4kg7A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ksa | MALONYL-COADECARBOXYLASE (Rhodopseudomonaspalustris) |
PF05292(MCD)PF17408(MCD_N) | 4 | GLY A 438ARG A 380ILE A 440PRO A 381 | None | 1.04A | 1rxcC-4ksaA:undetectable | 1rxcC-4ksaA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ky0 | PROTON/GLUTAMATESYMPORTER, SDFFAMILY (Thermococcuskodakarensis) |
PF00375(SDF) | 4 | GLY A 102GLN A 244ILE A 104VAL A 105 | None | 1.00A | 1rxcC-4ky0A:undetectable | 1rxcC-4ky0A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4me8 | SIGNAL PEPTIDASE I (Enterococcusfaecalis) |
PF00717(Peptidase_S24) | 4 | GLY A 163ILE A 60VAL A 164PRO A 54 | None | 0.81A | 1rxcC-4me8A:undetectable | 1rxcC-4me8A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nfy | D-3-PHOSPHOGLYCERATEDEHYDROGENASE,PUTATIVE (Entamoebahistolytica) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | GLY A 210MET A 230ILE A 184VAL A 183 | None | 0.99A | 1rxcC-4nfyA:undetectable | 1rxcC-4nfyA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nzs | BETA-KETOTHIOLASEBKTB (Cupriavidusnecator) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | MET A 158ILE A 292VAL A 328PRO A 294 | None | 1.06A | 1rxcC-4nzsA:undetectable | 1rxcC-4nzsA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p1l | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Chromohalobactersalexigens) |
PF03480(DctP) | 4 | GLY A 103MET A 179ILE A 105VAL A 106 | NoneBDP A 401 (-3.5A)NoneNone | 0.98A | 1rxcC-4p1lA:undetectable | 1rxcC-4p1lA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4plf | LACTATEDEHYDROGENASE (Apicomplexa) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLY A 230ARG A 99ILE A 232VAL A 233 | NonePYR A 402 (-3.8A)NoneNone | 0.98A | 1rxcC-4plfA:undetectable | 1rxcC-4plfA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qgs | ALCOHOLDEHYDROGENASE YQHD (Escherichiacoli) |
PF00465(Fe-ADH) | 4 | GLY A 270MET A 276ILE A 287VAL A 288 | None | 0.84A | 1rxcC-4qgsA:undetectable | 1rxcC-4qgsA:22.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r2w | URIDINEPHOSPHORYLASE (Shewanellaoneidensis) |
PF01048(PNP_UDP_1) | 7 | GLY A 93GLN A 163ARG A 165MET A 194ILE A 217VAL A 218PRO A 226 | NoneNoneNoneGOL A 303 (-3.5A)NoneNoneNone | 0.44A | 1rxcC-4r2wA:43.4 | 1rxcC-4r2wA:75.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r31 | URIDINEPHOSPHORYLASE (Actinobacillussuccinogenes) |
PF01048(PNP_UDP_1) | 6 | GLY A 94GLN A 164ARG A 166MET A 195ILE A 218VAL A 219 | NoneNoneNoneGOL A 301 (-4.0A)NoneNone | 0.62A | 1rxcC-4r31A:22.6 | 1rxcC-4r31A:66.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u39 | CELL DIVISION FACTORCELL DIVISIONPROTEIN FTSZ (Bacillussubtilis) |
PF00091(Tubulin)PF12327(FtsZ_C)PF13072(DUF3936) | 4 | GLY A 37MET J 6ILE A 14VAL A 38 | None | 0.98A | 1rxcC-4u39A:undetectable | 1rxcC-4u39A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v14 | MUTATOR MUTT PROTEIN (Vibrio cholerae) |
PF00293(NUDIX) | 4 | GLY A 38ARG A 53ILE A 6VAL A 7 | None | 0.92A | 1rxcC-4v14A:undetectable | 1rxcC-4v14A:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzb | NITROGENASE IRONPROTEIN 1 (Azotobactervinelandii) |
PF00142(Fer4_NifH) | 4 | GLY E 167ILE E 168VAL E 169PRO E 256 | None | 1.03A | 1rxcC-4wzbE:undetectable | 1rxcC-4wzbE:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zm4 | AMINOTRANSFERASE (Streptomycespactum) |
PF00202(Aminotran_3) | 4 | GLY A 407ARG A 438ILE A 58VAL A 408 | None | 1.03A | 1rxcC-4zm4A:undetectable | 1rxcC-4zm4A:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zpd | RNA-DIRECTED RNAPOLYMERASE (Enterovirus B) |
PF00680(RdRP_1) | 4 | GLY A 207GLN A 84ARG A 307ILE A 325 | None | 1.00A | 1rxcC-4zpdA:undetectable | 1rxcC-4zpdA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a96 | POLYHEDRIN (Cypovirus 14) |
PF17515(CPV_Polyhedrin) | 4 | GLY A 176MET A 173ILE A 115VAL A 177 | None | 1.03A | 1rxcC-5a96A:undetectable | 1rxcC-5a96A:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bmt | UNCHARACTERIZEDPROTEIN (Parabacteroidesmerdae) |
no annotation | 4 | GLY A 207MET A 213ILE A 142VAL A 205 | None | 1.00A | 1rxcC-5bmtA:undetectable | 1rxcC-5bmtA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ep8 | PYRIMIDINE-NUCLEOSIDE PHOSPHORYLASE (Bacillussubtilis) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | GLY A 355ILE A 247VAL A 87PRO A 242 | GLY A 355 ( 0.0A)ILE A 247 ( 0.6A)VAL A 87 ( 0.6A)PRO A 242 ( 1.1A) | 0.95A | 1rxcC-5ep8A:3.4 | 1rxcC-5ep8A:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqt | PROTEASOME-ACTIVATING NUCLEOTIDASE (Pyrococcushorikoshii) |
PF00004(AAA) | 5 | GLY A 110GLN A 114MET A 156ILE A 285PRO A 277 | NoneNoneNoneADP A 401 (-4.2A)None | 1.46A | 1rxcC-5eqtA:undetectable | 1rxcC-5eqtA:25.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7u | CYCLOALTERNAN-FORMING ENZYME (Listeriamonocytogenes) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16338(DUF4968)PF16990(CBM_35) | 4 | GLY A 355GLN A 584ILE A 263VAL A 262 | None | 0.97A | 1rxcC-5f7uA:undetectable | 1rxcC-5f7uA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5htk | 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 2 (Homo sapiens) |
PF00300(His_Phos_1)PF01591(6PF2K) | 4 | GLY A 222GLN A 248ILE A 219VAL A 218 | GOL A 607 (-3.3A)GOL A 607 ( 4.1A)NoneNone | 0.99A | 1rxcC-5htkA:undetectable | 1rxcC-5htkA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k1b | WD REPEAT-CONTAININGPROTEIN 48 (Homo sapiens) |
PF00400(WD40)PF11816(DUF3337) | 4 | GLY B 32ARG B 55MET B 428VAL B 33 | None | 1.04A | 1rxcC-5k1bB:undetectable | 1rxcC-5k1bB:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2q | SERINE/THREONINE-PROTEIN KINASE 40 (Homo sapiens) |
no annotation | 4 | GLY C 86ILE C 49VAL C 46PRO C 45 | None | 1.02A | 1rxcC-5l2qC:undetectable | 1rxcC-5l2qC:21.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lhv | URIDINEPHOSPHORYLASE (Vibrio cholerae) |
PF01048(PNP_UDP_1) | 5 | GLY A 95GLN A 165ARG A 167MET A 196ILE A 219 | URI A 303 ( 3.4A)URA A 304 ( 2.9A)URA A 304 ( 2.9A)URI A 303 ( 3.7A)None | 0.29A | 1rxcC-5lhvA:42.9 | 1rxcC-5lhvA:75.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m45 | ACETONE CARBOXYLASEBETA SUBUNIT (Xanthobacterautotrophicus) |
PF01968(Hydantoinase_A)PF05378(Hydant_A_N) | 4 | GLY B 143ARG B 138ILE B 97VAL B 98 | None | 0.87A | 1rxcC-5m45B:2.3 | 1rxcC-5m45B:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ofu | FBP PROTEIN (Leishmaniamajor) |
PF00316(FBPase) | 4 | GLY A 304ARG A 335ILE A 306VAL A 300 | None | 0.97A | 1rxcC-5ofuA:undetectable | 1rxcC-5ofuA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojs | TRANSCRIPTION-ASSOCIATED PROTEIN 1 (Saccharomycescerevisiae) |
PF00454(PI3_PI4_kinase)PF02259(FAT) | 4 | GLY T1681ARG T1731ILE T1678VAL T1677 | None | 1.06A | 1rxcC-5ojsT:undetectable | 1rxcC-5ojsT:5.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5pep | PEPSIN (Sus scrofa) |
PF00026(Asp) | 4 | GLY A 119MET A 80ILE A 30VAL A 29 | None | 1.06A | 1rxcC-5pepA:undetectable | 1rxcC-5pepA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t3e | BACILLAMIDESYNTHETASEHETEROCYCLIZATIONDOMAIN (Thermoactinomycesvulgaris) |
PF00668(Condensation) | 4 | GLY A1132GLN A 913ILE A1130VAL A1131 | None | 1.05A | 1rxcC-5t3eA:undetectable | 1rxcC-5t3eA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uoh | CARBOXYLESTERASE A (Mycobacteriumtuberculosis) |
PF00561(Abhydrolase_1) | 4 | GLY A 174ILE A 178VAL A 175PRO A 429 | None | 1.04A | 1rxcC-5uohA:undetectable | 1rxcC-5uohA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wzr | ALPHA-N-ACETYLGALACTOSAMINIDASE (Bifidobacteriumbifidum) |
PF11308(Glyco_hydro_129) | 4 | GLY A 509ARG A 501ILE A 140VAL A 138 | None | 0.92A | 1rxcC-5wzrA:undetectable | 1rxcC-5wzrA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnz | CRED (Streptomycescremeus) |
no annotation | 4 | GLY A 374ILE A 376VAL A 377PRO A 437 | None | 0.77A | 1rxcC-5xnzA:undetectable | 1rxcC-5xnzA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bfu | SPIKE PROTEIN (CoronavirusHKU15) |
no annotation | 4 | GLY A 915GLN A 582ILE A 563PRO A 938 | NAG A1914 ( 4.9A)NoneNoneNAG A1914 ( 4.6A) | 1.04A | 1rxcC-6bfuA:undetectable | 1rxcC-6bfuA:13.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6btm | ALTERNATIVE COMPLEXIII SUBUNIT C (Flavobacteriumjohnsoniae) |
no annotation | 4 | GLY C 312GLN C 358ILE C 310VAL C 311 | None | 1.06A | 1rxcC-6btmC:undetectable | 1rxcC-6btmC:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cdd | NPL4 ZINC FINGER (Chaetomiumthermophilum) |
no annotation | 4 | GLY A 284GLN A 312ILE A 345VAL A 344 | None | 0.99A | 1rxcC-6cddA:undetectable | 1rxcC-6cddA:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dt3 | NUCLEOSIDETRIPHOSPHATASE NUDI (Klebsiellapneumoniae) |
no annotation | 4 | GLY A 37ARG A 52ILE A 6VAL A 7 | None | 0.82A | 1rxcC-6dt3A:undetectable | 1rxcC-6dt3A:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eyu | BACTERIORHODOPSIN (CandidatusNanosalina sp.J07AB43) |
no annotation | 4 | GLY A 118GLN A 122ILE A 116VAL A 115 | RET A 301 (-3.1A)NoneNoneRET A 301 ( 4.2A) | 1.06A | 1rxcC-6eyuA:undetectable | 1rxcC-6eyuA:12.97 |