SIMILAR PATTERNS OF AMINO ACIDS FOR 1RXC_B_URFB2011_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cly | IGG FAB (HUMAN IGG1,KAPPA) (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | THR H 110GLY H 9MET H 89PRO H 214 | None | 0.83A | 1rxcB-1clyH:undetectable | 1rxcB-1clyH:24.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgj | ALDEHYDEOXIDOREDUCTASE (Desulfovibriodesulfuricans) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 4 | THR A 104GLY A 106ILE A 108VAL A 109 | None | 0.95A | 1rxcB-1dgjA:undetectable | 1rxcB-1dgjA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e9y | UREASE SUBUNIT BETA (Helicobacterpylori) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | THR B 71GLY B 99GLN B 105ILE B 69 | None | 0.93A | 1rxcB-1e9yB:undetectable | 1rxcB-1e9yB:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e9y | UREASE SUBUNIT BETA (Helicobacterpylori) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | THR B 170GLY B 159ILE B 172PRO B 174 | NoneNoneKCX B 219 ( 4.4A)None | 0.95A | 1rxcB-1e9yB:undetectable | 1rxcB-1e9yB:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebd | DIHYDROLIPOAMIDEDEHYDROGENASE (Geobacillusstearothermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | THR A 147GLY A 313ILE A 315VAL A 316 | FAD A 462 (-4.0A)FAD A 462 (-3.4A)NoneNone | 0.79A | 1rxcB-1ebdA:undetectable | 1rxcB-1ebdA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eye | DIHYDROPTEROATESYNTHASE I (Mycobacteriumtuberculosis) |
PF00809(Pterin_bind) | 4 | THR A 87GLY A 49ILE A 85VAL A 48 | None | 0.81A | 1rxcB-1eyeA:undetectable | 1rxcB-1eyeA:25.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iiw | SLR1257 PROTEIN (Synechocystissp. PCC 6803) |
PF00497(SBP_bac_3) | 4 | THR A 181GLY A 97ILE A 183VAL A 185 | None | 0.78A | 1rxcB-1iiwA:undetectable | 1rxcB-1iiwA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k2p | TYROSINE-PROTEINKINASE BTK (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | THR A 474GLY A 462ILE A 472VAL A 463 | None | 0.72A | 1rxcB-1k2pA:undetectable | 1rxcB-1k2pA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o2d | ALCOHOLDEHYDROGENASE,IRON-CONTAINING (Thermotogamaritima) |
PF00465(Fe-ADH) | 4 | THR A 252GLY A 197ILE A 247VAL A 246 | None | 0.76A | 1rxcB-1o2dA:undetectable | 1rxcB-1o2dA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o4s | ASPARTATEAMINOTRANSFERASE (Thermotogamaritima) |
PF00155(Aminotran_1_2) | 4 | GLY A 244MET A 238ILE A 267VAL A 94 | None | 0.89A | 1rxcB-1o4sA:undetectable | 1rxcB-1o4sA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oed | ACETYLCHOLINERECEPTOR PROTEIN,DELTA CHAIN (Torpedomarmorata) |
PF02932(Neur_chan_memb) | 4 | GLY C 301MET C 293ILE C 303VAL C 304 | None | 0.92A | 1rxcB-1oedC:undetectable | 1rxcB-1oedC:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p49 | STERYL-SULFATASE (Homo sapiens) |
PF00884(Sulfatase)PF14707(Sulfatase_C) | 4 | GLY A 344ILE A 39VAL A 378PRO A 379 | None | 0.93A | 1rxcB-1p49A:undetectable | 1rxcB-1p49A:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1poj | ISOASPARTYLDIPEPTIDASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 5 | THR A 82GLY A 75ARG A 169ILE A 302PRO A 291 | NoneAE1 A 401 (-3.5A)AE1 A 401 (-3.3A)NoneAE1 A 401 (-4.4A) | 1.48A | 1rxcB-1pojA:undetectable | 1rxcB-1pojA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q50 | GLUCOSE-6-PHOSPHATEISOMERASE (Leishmaniamexicana) |
PF00342(PGI) | 4 | GLN A 406ILE A 332VAL A 328PRO A 211 | None | 0.86A | 1rxcB-1q50A:undetectable | 1rxcB-1q50A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sy7 | CATALASE 1 (Neurosporacrassa) |
PF00199(Catalase)PF01965(DJ-1_PfpI)PF06628(Catalase-rel) | 4 | ARG A 224MET A 474ILE A 323PRO A 168 | None | 0.92A | 1rxcB-1sy7A:undetectable | 1rxcB-1sy7A:16.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t6k | PHENAZINEBIOSYNTHESIS PROTEINPHZF (Pseudomonasfluorescens) |
PF02567(PhzC-PhzF) | 4 | THR A 211GLY A 73GLN A 119PRO A 153 | SO4 A 301 (-3.9A)SO4 A 301 (-3.6A)NoneNone | 0.81A | 1rxcB-1t6kA:undetectable | 1rxcB-1t6kA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uwy | CARBOXYPEPTIDASE M (Homo sapiens) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | THR A 100GLY A 46ILE A 102VAL A 45 | None | 0.94A | 1rxcB-1uwyA:3.8 | 1rxcB-1uwyA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x44 | MYOSIN-BINDINGPROTEIN C, SLOW-TYPE (Homo sapiens) |
PF07679(I-set) | 4 | THR A 84GLY A 86ILE A 8VAL A 10 | None | 0.96A | 1rxcB-1x44A:undetectable | 1rxcB-1x44A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ypz | T CELL RECEPTORDELTA (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | THR E 135GLY E 180ILE E 159VAL E 160 | None | 0.93A | 1rxcB-1ypzE:undetectable | 1rxcB-1ypzE:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ay9 | AROMATIC AMINO ACIDAMINOTRANSFERASE (Paracoccusdenitrificans) |
PF00155(Aminotran_1_2) | 4 | THR A 105GLY A 75GLN A 284MET A 287 | None | 0.84A | 1rxcB-2ay9A:undetectable | 1rxcB-2ay9A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b0r | POSSIBLE ADENYLCYCLASE-ASSOCIATEDPROTEIN (Cryptosporidiumparvum) |
PF08603(CAP_C) | 4 | GLY A 108ILE A 128VAL A 129PRO A 130 | None | 0.92A | 1rxcB-2b0rA:undetectable | 1rxcB-2b0rA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bmb | FOLIC ACID SYNTHESISPROTEIN FOL1 (Saccharomycescerevisiae) |
PF00809(Pterin_bind)PF01288(HPPK) | 4 | THR A 637GLY A 593ILE A 635VAL A 592 | None | 0.74A | 1rxcB-2bmbA:undetectable | 1rxcB-2bmbA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f6k | METAL-DEPENDENTHYDROLASE (Lactobacillusplantarum) |
PF04909(Amidohydro_2) | 4 | GLN A 111ILE A 70VAL A 73PRO A 98 | None | 0.94A | 1rxcB-2f6kA:undetectable | 1rxcB-2f6kA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gmh | ELECTRON TRANSFERFLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE (Sus scrofa) |
PF05187(ETF_QO)PF13450(NAD_binding_8) | 4 | GLY A 293ILE A 240VAL A 292PRO A 303 | None | 0.88A | 1rxcB-2gmhA:undetectable | 1rxcB-2gmhA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gzm | GLUTAMATE RACEMASE (Bacillusanthracis) |
PF01177(Asp_Glu_race) | 4 | THR A 59GLY A 8ILE A 10VAL A 9 | None | 0.95A | 1rxcB-2gzmA:3.9 | 1rxcB-2gzmA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kpt | PUTATIVE SECRETEDPROTEIN (Corynebacteriumglutamicum) |
PF04536(TPM_phosphatase) | 4 | THR A 134GLY A 132GLN A 105VAL A 116 | None | 0.89A | 1rxcB-2kptA:undetectable | 1rxcB-2kptA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o0r | RV0858C(N-SUCCINYLDIAMINOPIMELATEAMINOTRANSFERASE) (Mycobacteriumtuberculosis) |
PF00155(Aminotran_1_2) | 4 | GLY A 53GLN A 56ILE A 50PRO A 268 | None | 0.94A | 1rxcB-2o0rA:undetectable | 1rxcB-2o0rA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oce | HYPOTHETICAL PROTEINPA5201 (Pseudomonasaeruginosa) |
PF00575(S1)PF09371(Tex_N)PF12836(HHH_3)PF16921(Tex_YqgF) | 4 | GLY A 660GLN A 643ILE A 704VAL A 661 | None | 0.93A | 1rxcB-2oceA:undetectable | 1rxcB-2oceA:16.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oxf | URIDINEPHOSPHORYLASE (Salmonellaenterica) |
PF01048(PNP_UDP_1) | 4 | GLY A1096GLN A1166ARG A1168MET A1197 | None | 0.70A | 1rxcB-2oxfA:43.4 | 1rxcB-2oxfA:97.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oxf | URIDINEPHOSPHORYLASE (Salmonellaenterica) |
PF01048(PNP_UDP_1) | 4 | GLY A1096GLN A1166MET A1197VAL A1221 | None | 0.73A | 1rxcB-2oxfA:43.4 | 1rxcB-2oxfA:97.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oxf | URIDINEPHOSPHORYLASE (Salmonellaenterica) |
PF01048(PNP_UDP_1) | 4 | THR A1094GLY A1096ILE A1220VAL A1221 | None | 0.26A | 1rxcB-2oxfA:43.4 | 1rxcB-2oxfA:97.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ppy | ENOYL-COA HYDRATASE (Geobacilluskaustophilus) |
PF00378(ECH_1) | 4 | THR A 112GLY A 133GLN A 190ILE A 135 | None | 0.77A | 1rxcB-2ppyA:undetectable | 1rxcB-2ppyA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2puz | IMIDAZOLONEPROPIONASE (Agrobacteriumfabrum) |
PF01979(Amidohydro_1) | 4 | THR A 125GLY A 93ARG A 140PRO A 334 | None | 0.93A | 1rxcB-2puzA:undetectable | 1rxcB-2puzA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v9p | REPLICATION PROTEINE1 (Deltapapillomavirus4) |
PF00519(PPV_E1_C) | 4 | GLN A 374ARG A 370ILE A 503VAL A 511 | None | 0.88A | 1rxcB-2v9pA:undetectable | 1rxcB-2v9pA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wu8 | GLUCOSE-6-PHOSPHATEISOMERASE (Mycobacteriumtuberculosis) |
PF00342(PGI) | 4 | GLN A 353ILE A 279VAL A 275PRO A 164 | None | 0.86A | 1rxcB-2wu8A:undetectable | 1rxcB-2wu8A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xzo | REGULATOR OFNONSENSE TRANSCRIPTS1 (Homo sapiens) |
PF04851(ResIII)PF13086(AAA_11)PF13087(AAA_12) | 4 | THR A 499GLY A 495GLN A 665ARG A 865 | MG A1006 ( 3.3A)ADP A1004 ( 3.2A)ALF A1005 (-3.0A)ALF A1005 (-3.1A) | 0.92A | 1rxcB-2xzoA:undetectable | 1rxcB-2xzoA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zxh | TRNA URIDINE5-CARBOXYMETHYLAMINOMETHYL MODIFICATIONENZYME MNMG (Aquifexaeolicus) |
PF01134(GIDA)PF13932(GIDA_assoc) | 4 | THR A 366GLY A 371ILE A 369VAL A 136 | None | 0.97A | 1rxcB-2zxhA:undetectable | 1rxcB-2zxhA:15.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3asm | RIBONUCLEASE HIII (Geobacillusstearothermophilus) |
PF01351(RNase_HII)PF11858(DUF3378) | 4 | GLY A 269ILE A 271VAL A 272PRO A 265 | None | 0.97A | 1rxcB-3asmA:undetectable | 1rxcB-3asmA:24.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b9g | IAG-NUCLEOSIDEHYDROLASE (Trypanosomavivax) |
PF01156(IU_nuc_hydro) | 4 | THR A 284ARG A 299ILE A 271VAL A 269 | None | 0.80A | 1rxcB-3b9gA:undetectable | 1rxcB-3b9gA:24.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bje | NUCLEOSIDEPHOSPHORYLASE,PUTATIVE (Trypanosomabrucei) |
PF01048(PNP_UDP_1) | 4 | THR A 85GLY A 88ILE A 92VAL A 89 | None | 0.95A | 1rxcB-3bjeA:31.0 | 1rxcB-3bjeA:25.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bje | NUCLEOSIDEPHOSPHORYLASE,PUTATIVE (Trypanosomabrucei) |
PF01048(PNP_UDP_1) | 5 | THR A 140GLY A 142GLN A 246ARG A 248MET A 285 | R1P A 401 (-3.0A)URA A 501 (-3.4A)URA A 501 (-3.0A)URA A 501 (-2.9A)R1P A 401 ( 3.9A) | 0.22A | 1rxcB-3bjeA:31.0 | 1rxcB-3bjeA:25.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efm | FERRIC ALCALIGINSIDEROPHORE RECEPTOR (Bordetellapertussis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | THR A 41GLY A 395ILE A 393VAL A 394 | None | 0.92A | 1rxcB-3efmA:undetectable | 1rxcB-3efmA:17.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euf | URIDINEPHOSPHORYLASE 1 (Homo sapiens) |
PF01048(PNP_UDP_1) | 5 | THR A 141GLY A 143GLN A 217ARG A 219MET A 249 | PO4 A 401 ( 3.0A)BAU A 400 (-3.3A)BAU A 400 (-3.1A)BAU A 400 (-3.0A)BAU A 400 (-3.8A) | 0.27A | 1rxcB-3eufA:26.8 | 1rxcB-3eufA:27.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdo | UNCHARACTERIZEDOXIDOREDUCTASE YVAA (Bacillussubtilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | GLY A 237MET A 209ILE A 239VAL A 240 | None | 0.93A | 1rxcB-3gdoA:undetectable | 1rxcB-3gdoA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h95 | NUCLEOSIDEDIPHOSPHATE-LINKEDMOIETY X MOTIF 6 (Homo sapiens) |
PF00293(NUDIX) | 4 | GLY A 145GLN A 143ILE A 225VAL A 146 | None | 0.94A | 1rxcB-3h95A:undetectable | 1rxcB-3h95A:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb4 | VP0VP3 (Parechovirus B) |
PF00073(Rhv) | 4 | THR B 175GLY B 172ARG B 102VAL C 75 | None | 0.96A | 1rxcB-3jb4B:undetectable | 1rxcB-3jb4B:24.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kiz | PHOSPHORIBOSYLFORMYLGLYCINAMIDINECYCLO-LIGASE (Cytophagahutchinsonii) |
PF02769(AIRS_C) | 4 | THR A 346GLY A 284ILE A 344VAL A 285 | None | 0.88A | 1rxcB-3kizA:undetectable | 1rxcB-3kizA:24.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kvy | URIDINEPHOSPHORYLASE (Bos taurus) |
PF01048(PNP_UDP_1) | 5 | THR A 140GLY A 142GLN A 216ARG A 218MET A 248 | SO4 A 311 ( 3.1A)URA A 312 (-3.3A)URA A 312 (-3.3A)URA A 312 (-2.9A)URA A 312 ( 3.7A) | 0.26A | 1rxcB-3kvyA:27.1 | 1rxcB-3kvyA:26.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3odh | OKRAI ENDONUCLEASE (Oceanobacterkriegii) |
PF02923(BamHI) | 4 | GLY A 118ILE A 76VAL A 74PRO A 82 | None | 0.93A | 1rxcB-3odhA:undetectable | 1rxcB-3odhA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oga | NUCLEOSIDETRIPHOSPHATASE NUDI (Salmonellaenterica) |
PF00293(NUDIX) | 4 | GLY A 37ARG A 52ILE A 6VAL A 7 | NoneNoneBME A 142 ( 4.7A)None | 0.96A | 1rxcB-3ogaA:undetectable | 1rxcB-3ogaA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3olm | E3 UBIQUITIN-PROTEINLIGASE RSP5 (Saccharomycescerevisiae) |
PF00397(WW)PF00632(HECT) | 4 | GLY A 553MET A 664ILE A 688VAL A 556 | None | 0.93A | 1rxcB-3olmA:undetectable | 1rxcB-3olmA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p0f | URIDINEPHOSPHORYLASE 2 (Homo sapiens) |
PF01048(PNP_UDP_1) | 5 | THR A 147GLY A 149GLN A 223ARG A 225MET A 255 | BAU A 400 (-4.5A)BAU A 400 (-3.5A)BAU A 400 (-3.1A)BAU A 400 (-2.8A)BAU A 400 (-3.9A) | 0.28A | 1rxcB-3p0fA:26.6 | 1rxcB-3p0fA:28.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p6l | SUGAR PHOSPHATEISOMERASE/EPIMERASE (Parabacteroidesdistasonis) |
PF01261(AP_endonuc_2) | 4 | GLY A 103GLN A 37ILE A 101VAL A 102 | NoneCIT A 303 ( 3.9A)NoneNone | 0.97A | 1rxcB-3p6lA:undetectable | 1rxcB-3p6lA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8l | GERANYLTRANSTRANSFERASE (Enterococcusfaecalis) |
PF00348(polyprenyl_synt) | 4 | THR A 177GLY A 152GLN A 153VAL A 172 | None | 0.96A | 1rxcB-3p8lA:undetectable | 1rxcB-3p8lA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q8n | 4-AMINOBUTYRATETRANSAMINASE (Mycolicibacteriumsmegmatis) |
PF00202(Aminotran_3) | 5 | THR A 120GLY A 122ARG A 307VAL A 285PRO A 286 | None | 1.25A | 1rxcB-3q8nA:undetectable | 1rxcB-3q8nA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgk | UREASE SUBUNIT BETA2 (Helicobactermustelae) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | THR C 169GLY C 159ILE C 171PRO C 173 | NoneNoneKCX C 218 ( 4.7A)None | 0.83A | 1rxcB-3qgkC:undetectable | 1rxcB-3qgkC:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qll | CITRATE LYASE (Yersinia pestis) |
PF03328(HpcH_HpaI) | 4 | THR A 102GLY A 133ILE A 140VAL A 137 | None | 0.93A | 1rxcB-3qllA:undetectable | 1rxcB-3qllA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rmj | 2-ISOPROPYLMALATESYNTHASE (Neisseriameningitidis) |
PF00682(HMGL-like) | 4 | THR A 265GLY A 322ILE A 268VAL A 269 | None | 0.85A | 1rxcB-3rmjA:undetectable | 1rxcB-3rmjA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u37 | ACETYL-XYLANESTERASE EST2A (Butyrivibrioproteoclasticus) |
PF13472(Lipase_GDSL_2) | 4 | GLY A 146MET A 172ILE A 143PRO A 352 | None | 0.93A | 1rxcB-3u37A:2.8 | 1rxcB-3u37A:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbn | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrococcusfuriosus) |
PF01554(MatE) | 4 | GLY A 108MET A 115ILE A 150VAL A 151 | NoneNoneOLC A 505 ( 4.4A)None | 0.88A | 1rxcB-3wbnA:undetectable | 1rxcB-3wbnA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bzg | ALDOSE 1-EPIMERASE (Bacillussubtilis) |
PF01263(Aldose_epim) | 5 | THR A 178GLY A 65GLN A 46ILE A 66VAL A 35 | None | 1.46A | 1rxcB-4bzgA:undetectable | 1rxcB-4bzgA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c30 | DNA HELICASE II (Deinococcusradiodurans) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 4 | THR A 39GLY A 35GLN A 258ARG A 617 | MG A1663 ( 2.8A)ANP A1662 (-3.1A)ANP A1662 (-3.2A)ANP A1662 (-3.0A) | 0.85A | 1rxcB-4c30A:undetectable | 1rxcB-4c30A:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4em6 | GLUCOSE-6-PHOSPHATEISOMERASE (Brucellamelitensis) |
no annotation | 4 | GLN D 349ILE D 275VAL D 271PRO D 161 | None | 0.87A | 1rxcB-4em6D:undetectable | 1rxcB-4em6D:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4faj | PRGZ (Enterococcusfaecalis) |
PF00496(SBP_bac_5) | 4 | GLY A 427GLN A 431VAL A 417PRO A 447 | None | 0.96A | 1rxcB-4fajA:undetectable | 1rxcB-4fajA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fxs | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Vibrio cholerae) |
PF00478(IMPDH)PF00571(CBS) | 4 | THR A 266GLY A 293ILE A 275VAL A 294 | None | 0.93A | 1rxcB-4fxsA:undetectable | 1rxcB-4fxsA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g7e | UREASE (Cajanus cajan) |
PF00449(Urease_alpha)PF00547(Urease_gamma)PF00699(Urease_beta)PF01979(Amidohydro_1) | 4 | THR B 385GLY B 326ILE B 321VAL B 320 | None | 0.96A | 1rxcB-4g7eB:undetectable | 1rxcB-4g7eB:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ix2 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Vibrio cholerae) |
PF00478(IMPDH) | 4 | THR A 266GLY A 293ILE A 275VAL A 294 | None | 0.95A | 1rxcB-4ix2A:undetectable | 1rxcB-4ix2A:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j9u | TRK SYSTEM POTASSIUMUPTAKE PROTEIN TRKH (Vibrioparahaemolyticus) |
PF02386(TrkH) | 4 | THR A 352GLY A 141ILE A 143VAL A 144 | None | 0.83A | 1rxcB-4j9uA:undetectable | 1rxcB-4j9uA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kg7 | PEPTIDASE S8 ANDS53, SUBTILISIN,KEXIN, SEDOLISIN (Mycolicibacteriumsmegmatis) |
PF00082(Peptidase_S8) | 4 | GLY A 291GLN A 375VAL A 287PRO A 308 | None | 0.86A | 1rxcB-4kg7A:undetectable | 1rxcB-4kg7A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l9r | INOSITOL2-DEHYDROGENASE/D-CHIRO-INOSITOL3-DEHYDROGENASE (Bacillussubtilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | THR A 34GLY A 6ILE A 8VAL A 70 | None | 0.91A | 1rxcB-4l9rA:undetectable | 1rxcB-4l9rA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4me8 | SIGNAL PEPTIDASE I (Enterococcusfaecalis) |
PF00717(Peptidase_S24) | 4 | GLY A 163ILE A 60VAL A 164PRO A 54 | None | 0.95A | 1rxcB-4me8A:undetectable | 1rxcB-4me8A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mio | INOSITOL2-DEHYDROGENASE/D-CHIRO-INOSITOL3-DEHYDROGENASE (Lactobacilluscasei) |
PF01408(GFO_IDH_MocA) | 4 | THR A 34GLY A 6ILE A 8VAL A 70 | NAI A 401 ( 4.9A)NoneNoneNone | 0.89A | 1rxcB-4mioA:undetectable | 1rxcB-4mioA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxb | UREIDOGLYCOLATEHYDROLASE (Arabidopsisthaliana) |
PF01546(Peptidase_M20) | 4 | THR A 272GLY A 436ILE A 401VAL A 400 | None | 0.96A | 1rxcB-4pxbA:10.5 | 1rxcB-4pxbA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qgs | ALCOHOLDEHYDROGENASE YQHD (Escherichiacoli) |
PF00465(Fe-ADH) | 4 | GLY A 270MET A 276ILE A 287VAL A 288 | None | 0.81A | 1rxcB-4qgsA:undetectable | 1rxcB-4qgsA:22.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r2w | URIDINEPHOSPHORYLASE (Shewanellaoneidensis) |
PF01048(PNP_UDP_1) | 8 | THR A 91GLY A 93GLN A 163ARG A 165MET A 194ILE A 217VAL A 218PRO A 226 | SO4 A 302 ( 3.0A)NoneNoneNoneGOL A 303 (-3.5A)NoneNoneNone | 0.21A | 1rxcB-4r2wA:43.4 | 1rxcB-4r2wA:75.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r31 | URIDINEPHOSPHORYLASE (Actinobacillussuccinogenes) |
PF01048(PNP_UDP_1) | 5 | GLY A 94GLN A 164ARG A 166MET A 195VAL A 219 | NoneNoneNoneGOL A 301 (-4.0A)None | 0.60A | 1rxcB-4r31A:41.7 | 1rxcB-4r31A:66.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r31 | URIDINEPHOSPHORYLASE (Actinobacillussuccinogenes) |
PF01048(PNP_UDP_1) | 5 | GLY A 94GLN A 164MET A 195ILE A 218VAL A 219 | NoneNoneGOL A 301 (-4.0A)NoneNone | 0.74A | 1rxcB-4r31A:41.7 | 1rxcB-4r31A:66.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r31 | URIDINEPHOSPHORYLASE (Actinobacillussuccinogenes) |
PF01048(PNP_UDP_1) | 4 | THR A 92GLY A 94ARG A 166VAL A 219 | None | 0.87A | 1rxcB-4r31A:41.7 | 1rxcB-4r31A:66.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r31 | URIDINEPHOSPHORYLASE (Actinobacillussuccinogenes) |
PF01048(PNP_UDP_1) | 4 | THR A 92GLY A 94ILE A 218VAL A 219 | None | 0.24A | 1rxcB-4r31A:41.7 | 1rxcB-4r31A:66.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7f | UNCHARACTERIZEDPROTEIN (Parabacteroidesmerdae) |
PF17116(DUF5103) | 4 | THR A 415GLY A 413ILE A 397VAL A 399 | None | 0.94A | 1rxcB-4r7fA:undetectable | 1rxcB-4r7fA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7u | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Vibrio cholerae) |
PF00275(EPSP_synthase) | 4 | THR A 312GLY A 322ILE A 324VAL A 323 | None | 0.93A | 1rxcB-4r7uA:undetectable | 1rxcB-4r7uA:24.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u39 | CELL DIVISION FACTORCELL DIVISIONPROTEIN FTSZ (Bacillussubtilis) |
PF00091(Tubulin)PF12327(FtsZ_C)PF13072(DUF3936) | 4 | GLY A 37MET J 6ILE A 14VAL A 38 | None | 0.95A | 1rxcB-4u39A:3.9 | 1rxcB-4u39A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yry | DIHYDROPYRIMIDINEDEHYDROGENASESUBUNIT A (Thermotogamaritima) |
PF07992(Pyr_redox_2)PF14691(Fer4_20) | 4 | THR B 233GLY B 431ILE B 434VAL B 435 | FAD B 503 (-3.8A)NoneNoneNone | 0.84A | 1rxcB-4yryB:undetectable | 1rxcB-4yryB:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zow | MULTIDRUGTRANSPORTER MDFA (Escherichiacoli) |
PF07690(MFS_1) | 4 | THR A 109GLN A 37ILE A 105VAL A 44 | None | 0.95A | 1rxcB-4zowA:undetectable | 1rxcB-4zowA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxw | C-DOMAIN TYPE IIPEPTIDE SYNTHETASE (Streptomycesglobisporus) |
PF00668(Condensation) | 4 | MET A 26ILE A 365VAL A 367PRO A 289 | NoneNone4T7 A 501 (-4.8A)None | 0.88A | 1rxcB-4zxwA:undetectable | 1rxcB-4zxwA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cyf | PUTATIVE URIDINEPHOSPHORYLASE (Schistosomamansoni) |
PF01048(PNP_UDP_1) | 4 | THR A 124ARG A 203MET A 233VAL A 257 | FLC A 301 (-3.7A)NoneNoneNone | 0.39A | 1rxcB-5cyfA:26.2 | 1rxcB-5cyfA:25.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ep8 | PYRIMIDINE-NUCLEOSIDE PHOSPHORYLASE (Bacillussubtilis) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | GLY A 355ILE A 247VAL A 87PRO A 242 | GLY A 355 ( 0.0A)ILE A 247 ( 0.6A)VAL A 87 ( 0.6A)PRO A 242 ( 1.1A) | 0.97A | 1rxcB-5ep8A:3.4 | 1rxcB-5ep8A:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g2v | N-ACETYLGLUCOSAMINE-6-SULFATASE (Bacteroidesthetaiotaomicron) |
PF00884(Sulfatase)PF16347(DUF4976) | 4 | THR A 400GLY A 415ARG A 433VAL A 395 | None | 0.96A | 1rxcB-5g2vA:undetectable | 1rxcB-5g2vA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2q | SERINE/THREONINE-PROTEIN KINASE 40 (Homo sapiens) |
no annotation | 4 | GLY C 86ILE C 49VAL C 46PRO C 45 | None | 0.94A | 1rxcB-5l2qC:undetectable | 1rxcB-5l2qC:21.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5lhv | URIDINEPHOSPHORYLASE (Vibrio cholerae) |
PF01048(PNP_UDP_1) | 6 | THR A 93GLY A 95GLN A 165ARG A 167MET A 196ILE A 219 | SO4 A 301 ( 2.9A)URI A 303 ( 3.4A)URA A 304 ( 2.9A)URA A 304 ( 2.9A)URI A 303 ( 3.7A)None | 0.23A | 1rxcB-5lhvA:24.3 | 1rxcB-5lhvA:75.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ofu | FBP PROTEIN (Leishmaniamajor) |
PF00316(FBPase) | 4 | GLY A 304ARG A 335ILE A 306VAL A 300 | None | 0.95A | 1rxcB-5ofuA:undetectable | 1rxcB-5ofuA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opi | TAP BINDINGPROTEIN-LIKE VARIANT (Homo sapiens) |
no annotation | 4 | THR C 256GLN C 218ARG C 216ILE C 257 | None | 0.90A | 1rxcB-5opiC:undetectable | 1rxcB-5opiC:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opq | 3,6-ANHYDRO-D-GALACTOSIDASE (Zobelliagalactanivorans) |
no annotation | 4 | THR A 592GLY A 335MET A 586ILE A 337 | None | 0.81A | 1rxcB-5opqA:undetectable | 1rxcB-5opqA:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uoh | CARBOXYLESTERASE A (Mycobacteriumtuberculosis) |
PF00561(Abhydrolase_1) | 4 | GLY A 174ILE A 178VAL A 175PRO A 429 | None | 0.88A | 1rxcB-5uohA:undetectable | 1rxcB-5uohA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vat | PENICILLIN-BINDINGPROTEIN ACTIVATORLPOA (Haemophilusinfluenzae) |
PF04348(LppC) | 4 | GLY A 391ARG A 465VAL A 394PRO A 362 | None | 0.89A | 1rxcB-5vatA:undetectable | 1rxcB-5vatA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnz | CRED (Streptomycescremeus) |
no annotation | 4 | GLY A 374ILE A 376VAL A 377PRO A 437 | None | 0.98A | 1rxcB-5xnzA:undetectable | 1rxcB-5xnzA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yjh | PERIOSTIN (Homo sapiens) |
no annotation | 4 | THR A 104GLY A 109ILE A 107PRO A 81 | MG A 720 (-3.1A)None MG A 720 ( 4.7A)None | 0.95A | 1rxcB-5yjhA:undetectable | 1rxcB-5yjhA:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bfu | SPIKE PROTEIN (CoronavirusHKU15) |
no annotation | 4 | GLY A 915GLN A 582ILE A 563PRO A 938 | NAG A1914 ( 4.9A)NoneNoneNAG A1914 ( 4.6A) | 0.97A | 1rxcB-6bfuA:undetectable | 1rxcB-6bfuA:13.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dt3 | NUCLEOSIDETRIPHOSPHATASE NUDI (Klebsiellapneumoniae) |
no annotation | 4 | GLY A 37ARG A 52ILE A 6VAL A 7 | None | 0.97A | 1rxcB-6dt3A:undetectable | 1rxcB-6dt3A:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6h20 | - (-) |
no annotation | 4 | GLN A 184ILE A 226VAL A 205PRO A 224 | None | 0.90A | 1rxcB-6h20A:undetectable | 1rxcB-6h20A:undetectable |