SIMILAR PATTERNS OF AMINO ACIDS FOR 1RMT_D_ADND1504_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebv PROSTAGLANDIN H2
SYNTHASE

(Ovis aries) 		PF00008
(EGF)
PF03098
(An_peroxidase) 		4 ASP A 158
TYR A  39
ASP A 135
THR A 161
 None
 0.97A 1rmtD-1ebvA:
undetectable		 1rmtD-1ebvA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ewr DNA MISMATCH REPAIR
PROTEIN MUTS

(Thermus
aquaticus) 		PF00488
(MutS_V)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		4 ASP A 277
PHE A 273
LEU A 292
THR A 271
 None
 0.99A 1rmtD-1ewrA:
undetectable		 1rmtD-1ewrA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gs9 APOLIPOPROTEIN E

(Homo sapiens) 		PF01442
(Apolipoprotein) 		4 PHE A  33
LEU A 148
ASP A 110
THR A  67
 None
 0.92A 1rmtD-1gs9A:
undetectable		 1rmtD-1gs9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h0h FORMATE
DEHYDROGENASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 PHE A 513
TYR A 139
LEU A 143
TRP A 142
 None
 0.89A 1rmtD-1h0hA:
1.6		 1rmtD-1h0hA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5x SURVIVAL PROTEIN E

(Pyrobaculum
aerophilum) 		PF01975
(SurE) 		4 LEU A 255
ASP A 251
THR A 152
TYR A 155
 None
 1.04A 1rmtD-1l5xA:
3.1		 1rmtD-1l5xA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4

(Mus musculus) 		PF00412
(LIM) 		4 ASP A  61
ASP A  83
THR A  51
TYR A  50
 ZN  A 124 (-2.7A)
None
None
None
 0.99A 1rmtD-1m3vA:
undetectable		 1rmtD-1m3vA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE

(Solanum
tuberosum) 		PF01536
(SAM_decarbox) 		4 ASP A 296
LEU A 302
THR A 183
TYR A 182
 None
 1.00A 1rmtD-1mhmA:
undetectable		 1rmtD-1mhmA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pe9 PECTATE LYASE A

(Dickeya
chrysanthemi) 		PF00544
(Pec_lyase_C) 		4 ASP A 170
ASP A 164
THR A 173
TYR A 172
 None
 0.89A 1rmtD-1pe9A:
undetectable		 1rmtD-1pe9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1poy SPERMIDINE/PUTRESCIN
E-BINDING PROTEIN

(Escherichia
coli) 		PF13416
(SBP_bac_8) 		4 LEU 1 154
TRP 1 155
ASP 1 153
THR 1 134
 None
 1.06A 1rmtD-1poy1:
undetectable		 1rmtD-1poy1:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pww LETHAL FACTOR

(Bacillus
anthracis) 		PF07737
(ATLF)
PF09156
(Anthrax-tox_M) 		4 PHE A 629
LEU A 603
TRP A 606
THR A 584
 None
 0.86A 1rmtD-1pwwA:
undetectable		 1rmtD-1pwwA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus) 		PF00028
(Cadherin) 		4 TYR A 148
LEU A 146
ASP A 195
THR A 109
 None
None
CA  A 905 (-2.6A)
None
 1.06A 1rmtD-1q5aA:
undetectable		 1rmtD-1q5aA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qh5 PROTEIN
(HYDROXYACYLGLUTATHI
ONE HYDROLASE)

(Homo sapiens) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		4 TYR A  13
ASP A  58
THR A 176
TYR A 175
 None
ZN  A 262 (-2.7A)
None
GSH  A 463 (-4.5A)
 1.12A 1rmtD-1qh5A:
undetectable		 1rmtD-1qh5A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3i PROBABLE CYSTEINE
DESULFURASE

(Synechocystis
sp.) 		PF00266
(Aminotran_5) 		4 PHE A 240
LEU A 291
THR A  96
TYR A  95
 None
 1.10A 1rmtD-1t3iA:
3.5		 1rmtD-1t3iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1umi F-BOX ONLY PROTEIN 2

(Mus musculus) 		PF04300
(FBA) 		4 ASP A 209
PHE A 270
LEU A 128
TRP A 140
 None
 1.00A 1rmtD-1umiA:
undetectable		 1rmtD-1umiA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xbz 3-KETO-L-GULONATE
6-PHOSPHATE
DECARBOXYLASE

(Escherichia
coli) 		PF00215
(OMPdecase) 		4 ASP A  16
LEU A  38
THR A  21
TYR A  19
 None
 1.06A 1rmtD-1xbzA:
undetectable		 1rmtD-1xbzA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a3l AMP DEAMINASE

(Arabidopsis
thaliana) 		PF00962
(A_deaminase) 		4 PHE A 328
TYR A 261
LEU A 674
THR A 330
 None
 1.04A 1rmtD-2a3lA:
undetectable		 1rmtD-2a3lA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayu NUCLEOSOME ASSEMBLY
PROTEIN

(Saccharomyces
cerevisiae) 		PF00956
(NAP) 		4 ASP A 341
PHE A 315
LEU A 348
THR A 202
 None
 1.03A 1rmtD-2ayuA:
undetectable		 1rmtD-2ayuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e32 F-BOX ONLY PROTEIN 2

(Mus musculus) 		PF00646
(F-box)
PF04300
(FBA) 		4 ASP A 209
PHE A 270
LEU A 128
TRP A 140
 None
 1.11A 1rmtD-2e32A:
undetectable		 1rmtD-2e32A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e8n EPHRIN TYPE-A
RECEPTOR 2

(Homo sapiens) 		PF00536
(SAM_1) 		4 PHE A  31
LEU A  19
TRP A  18
TYR A  27
 None
 1.03A 1rmtD-2e8nA:
undetectable		 1rmtD-2e8nA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		4 ASP A 563
TYR A 296
ASP A 461
THR A 558
 None
None
None
SF4  A 610 ( 4.5A)
 1.07A 1rmtD-2gmhA:
undetectable		 1rmtD-2gmhA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsk VITAMIN B12
TRANSPORTER BTUB

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 ASP A 278
TYR A 229
THR A 289
TYR A 277
 None
CNC  A 701 ( 3.5A)
CNC  A 701 (-3.4A)
None
 1.04A 1rmtD-2gskA:
undetectable		 1rmtD-2gskA:
15.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hf7 CLASS B ACID
PHOSPHATASE

(Escherichia
coli) 		PF03767
(Acid_phosphat_B) 		8 ASP A  46
PHE A  56
TYR A  70
LEU A  71
TRP A  77
ASP A 145
THR A 192
TYR A 193
 AF3  A 800 ( 3.7A)
None
None
None
None
None
None
None
 0.44A 1rmtD-2hf7A:
36.7		 1rmtD-2hf7A:
99.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ibd POSSIBLE
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii) 		PF00440
(TetR_N) 		4 ASP A 185
LEU A 192
THR A  97
TYR A  99
 None
 0.95A 1rmtD-2ibdA:
undetectable		 1rmtD-2ibdA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivf ETHYLBENZENE
DEHYDROGENASE
ALPHA-SUBUNIT

(Aromatoleum
aromaticum) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 ASP A 675
PHE A 673
LEU A 740
THR A 672
 None
 1.09A 1rmtD-2ivfA:
undetectable		 1rmtD-2ivfA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jzl CYANOVIRIN-N HOMOLOG

(Neurospora
crassa) 		PF08881
(CVNH) 		4 ASP A  63
LEU A  78
ASP A  93
THR A  58
 None
 0.98A 1rmtD-2jzlA:
undetectable		 1rmtD-2jzlA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2llf VILLIN-1

(Gallus gallus) 		PF00626
(Gelsolin) 		4 PHE A  89
LEU A  34
ASP A  20
THR A  88
 None
 1.08A 1rmtD-2llfA:
undetectable		 1rmtD-2llfA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ooq RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE T

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 ASP A1120
PHE A1116
LEU A1084
THR A1113
 None
 1.11A 1rmtD-2ooqA:
undetectable		 1rmtD-2ooqA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qed HYDROXYACYLGLUTATHIO
NE HYDROLASE

(Salmonella
enterica) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		4 TYR A  13
ASP A  57
THR A 168
TYR A 167
 None
FE  A 252 (-2.6A)
None
None
 1.09A 1rmtD-2qedA:
undetectable		 1rmtD-2qedA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qq8 TBC1 DOMAIN FAMILY
MEMBER 14

(Homo sapiens) 		PF00566
(RabGAP-TBC) 		4 ASP A 565
LEU A 562
THR A 628
TYR A 567
 None
 0.89A 1rmtD-2qq8A:
undetectable		 1rmtD-2qq8A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qxl HEAT SHOCK PROTEIN
HOMOLOG SSE1

(Saccharomyces
cerevisiae) 		PF00012
(HSP70) 		4 PHE A   5
LEU A 166
ASP A 124
THR A   3
 None
 1.09A 1rmtD-2qxlA:
undetectable		 1rmtD-2qxlA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yeq ALKALINE PHOSPHATASE
D

(Bacillus
subtilis) 		PF09423
(PhoD)
PF16655
(PhoD_N) 		4 ASP A  80
LEU A  25
TRP A  48
THR A 106
 None
 1.10A 1rmtD-2yeqA:
undetectable		 1rmtD-2yeqA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE

(Flavobacterium
sp.) 		PF00144
(Beta-lactamase) 		4 PHE A  85
LEU A  73
ASP A 384
THR A  82
 None
None
MES  A 503 ( 3.9A)
None
 1.12A 1rmtD-2zm2A:
undetectable		 1rmtD-2zm2A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g1n E3 UBIQUITIN-PROTEIN
LIGASE HUWE1

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A4128
TYR A4133
THR A4090
TYR A4127
 None
 1.10A 1rmtD-3g1nA:
undetectable		 1rmtD-3g1nA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwf CYCLOHEXANONE
MONOOXYGENASE

(Rhodococcus sp.
HI-31) 		PF00743
(FMO-like) 		4 PHE A 530
LEU A 414
TRP A 447
THR A 466
 None
 1.10A 1rmtD-3gwfA:
undetectable		 1rmtD-3gwfA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ifs GLUCOSE-6-PHOSPHATE
ISOMERASE

(Bacillus
anthracis) 		PF00342
(PGI) 		4 LEU A  46
TRP A  48
ASP A  50
THR A  31
 None
 1.03A 1rmtD-3ifsA:
2.0		 1rmtD-3ifsA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		4 PHE X1082
TYR X1248
LEU X1126
THR X1243
 None
 0.98A 1rmtD-3jb9X:
undetectable		 1rmtD-3jb9X:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lg5 EPI-ISOZIZAENE
SYNTHASE

(Streptomyces
coelicolor) 		no annotation 4 PHE A 165
TYR A  91
TRP A  94
ASP A  99
 None
None
None
MG  A 701 (-2.5A)
 0.91A 1rmtD-3lg5A:
undetectable		 1rmtD-3lg5A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n0g ISOPRENE SYNTHASE

(Populus tremula
x Populus alba) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 PHE A 435
ASP A 490
THR A 434
TYR A 438
 None
MG  A 622 ( 4.5A)
None
None
 1.12A 1rmtD-3n0gA:
undetectable		 1rmtD-3n0gA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus musculus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 PHE A 142
TYR A 179
LEU A 183
TYR A 153
 None
 1.12A 1rmtD-3o76A:
undetectable		 1rmtD-3o76A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdi NITROGENASE MOFE
COFACTOR
BIOSYNTHESIS PROTEIN
NIFE

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro) 		4 PHE A 287
LEU A 291
ASP A 197
THR A 300
 None
 1.09A 1rmtD-3pdiA:
undetectable		 1rmtD-3pdiA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sei CASKIN-1

(Homo sapiens) 		PF00536
(SAM_1) 		4 PHE A  26
LEU A  14
TRP A  13
TYR A  22
 None
 0.97A 1rmtD-3seiA:
undetectable		 1rmtD-3seiA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3srz TOXIN A

(Clostridioides
difficile) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 PHE A  58
LEU A  71
THR A  25
TYR A  23
 None
 1.11A 1rmtD-3srzA:
undetectable		 1rmtD-3srzA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tal DNA DOUBLE-STRAND
BREAK REPAIR PROTEIN
NURA

(Pyrococcus
furiosus) 		PF09376
(NurA) 		4 PHE A 347
TYR A 276
LEU A 280
ASP A 284
 None
 1.09A 1rmtD-3talA:
undetectable		 1rmtD-3talA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE

(Helicobacter
pylori) 		PF00348
(polyprenyl_synt) 		4 ASP A 200
TYR A 155
LEU A 159
THR A 272
 MG  A 500 (-2.9A)
None
None
None
 0.96A 1rmtD-3tc1A:
undetectable		 1rmtD-3tc1A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tn2 C-C MOTIF CHEMOKINE
4

(Homo sapiens) 		PF00048
(IL8) 		4 PHE A  42
LEU A  66
ASP A  65
THR A  44
 None
 1.01A 1rmtD-3tn2A:
undetectable		 1rmtD-3tn2A:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u34 GENERAL STRESS
PROTEIN

(Xanthomonas
citri) 		PF16242
(Pyrid_ox_like) 		4 PHE A  70
LEU A 107
ASP A 143
THR A  72
 None
 1.09A 1rmtD-3u34A:
undetectable		 1rmtD-3u34A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3um1 BRO1
DOMAIN-CONTAINING
PROTEIN BROX

(Homo sapiens) 		PF03097
(BRO1) 		4 PHE A 373
TRP A 365
ASP A  35
THR A  25
 None
 1.10A 1rmtD-3um1A:
undetectable		 1rmtD-3um1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v9e LACCASE

(Botrytis aclada) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 TYR A 118
LEU A 116
ASP A 114
THR A 106
 None
 1.12A 1rmtD-3v9eA:
undetectable		 1rmtD-3v9eA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wso F-BOX ONLY PROTEIN
44

(Homo sapiens) 		PF04300
(FBA)
PF12937
(F-box-like) 		4 ASP A 162
PHE A 225
LEU A  82
TRP A  94
 None
 1.03A 1rmtD-3wsoA:
undetectable		 1rmtD-3wsoA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zq3 OBP3 PROTEIN

(Rattus
norvegicus) 		PF00061
(Lipocalin) 		4 ASP A  32
TYR A  99
LEU A  71
ASP A  65
 None
 1.03A 1rmtD-3zq3A:
undetectable		 1rmtD-3zq3A:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ah6 ASPARTATE--TRNA
LIGASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 ASP A 334
LEU A 479
THR A 330
TYR A 328
 None
 0.96A 1rmtD-4ah6A:
undetectable		 1rmtD-4ah6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akr F-ACTIN-CAPPING
PROTEIN SUBUNIT
ALPHA
F-ACTIN-CAPPING
PROTEIN SUBUNIT BETA

(Dictyostelium
discoideum) 		PF01115
(F_actin_cap_B)
PF01267
(F-actin_cap_A) 		4 LEU B 195
ASP A 197
THR B 238
TYR A 194
 None
 1.04A 1rmtD-4akrB:
undetectable		 1rmtD-4akrB:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2q ATP SYNTHASE SUBUNIT
BETA, MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 ASP D 349
LEU D 317
ASP D 315
THR D 332
 None
 0.97A 1rmtD-4b2qD:
undetectable		 1rmtD-4b2qD:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7g BETA-N-ACETYLHEXOSAM
INIDASE

(Streptomyces
coelicolor) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b) 		5 ASP A 441
PHE A 445
TYR A 168
LEU A 167
ASP A 163
 None
 1.41A 1rmtD-4c7gA:
undetectable		 1rmtD-4c7gA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4csb VIRULENCE ASSOCIATED
PROTEIN VAPD

(Rhodococcus
hoagii) 		PF05526
(R_equi_Vir) 		4 ASP A  48
TYR A  85
LEU A  81
THR A  45
 None
 0.93A 1rmtD-4csbA:
undetectable		 1rmtD-4csbA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecg PUTATIVE
IRON-REGULATED
PROTEIN A

(Parabacteroides
distasonis) 		PF09375
(Peptidase_M75) 		4 ASP A 127
TYR A  70
LEU A 213
ASP A 209
 CA  A 503 ( 4.1A)
None
None
None
 1.05A 1rmtD-4ecgA:
undetectable		 1rmtD-4ecgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g54 GENERAL SECRETION
PATHWAY PROTEIN

(Vibrio
vulnificus) 		PF01471
(PG_binding_1) 		4 TYR A 363
LEU A 454
ASP A 453
THR A 382
 None
 0.92A 1rmtD-4g54A:
undetectable		 1rmtD-4g54A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gzu FERM, RHOGEF AND
PLECKSTRIN
DOMAIN-CONTAINING
PROTEIN 2

(Mus musculus) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 ASP A 968
ASP A 556
THR A 964
TYR A 962
 None
 0.84A 1rmtD-4gzuA:
undetectable		 1rmtD-4gzuA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iel GLUTATHIONE
S-TRANSFERASE,
N-TERMINAL DOMAIN
PROTEIN

(Burkholderia
ambifaria) 		PF13417
(GST_N_3) 		4 PHE A 152
TYR A 188
LEU A 192
THR A 159
 None
 1.07A 1rmtD-4ielA:
undetectable		 1rmtD-4ielA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oe5 DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00171
(Aldedh) 		4 ASP A 460
ASP A 486
THR A 466
TYR A 463
 None
 0.99A 1rmtD-4oe5A:
2.3		 1rmtD-4oe5A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		4 ASP A1784
TYR A1792
LEU A1788
ASP A1781
 None
 0.76A 1rmtD-4r04A:
undetectable		 1rmtD-4r04A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r84 SIALYLTRANSFERASE
0160

(Photobacterium
damselae) 		PF11477
(PM0188) 		4 ASP A 242
TYR A 293
LEU A 300
ASP A 302
 None
 1.01A 1rmtD-4r84A:
2.6		 1rmtD-4r84A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9v SIALYLTRANSFERASE
0160

(Photobacterium
damselae) 		PF11477
(PM0188) 		4 ASP A 242
TYR A 293
LEU A 300
ASP A 302
 None
 1.08A 1rmtD-4r9vA:
2.6		 1rmtD-4r9vA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4trr PUTATIVE
D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00106
(adh_short) 		4 ASP A 116
TYR A 140
LEU A 166
THR A 121
 None
 1.10A 1rmtD-4trrA:
5.0		 1rmtD-4trrA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wfq SUPPRESSOR OF
STEM-LOOP PROTEIN 1

(Saccharomyces
cerevisiae) 		PF04056
(Ssl1) 		5 ASP A 284
PHE A 287
LEU A 308
THR A 280
TYR A 282
 None
 1.27A 1rmtD-4wfqA:
2.0		 1rmtD-4wfqA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y23 GAMMA GLUTAMYL
TRANSPEPTIDASE,GAMMA
-GLUTAMYLTRANSPEPTID
ASE

(Bacillus
licheniformis) 		PF01019
(G_glu_transpept) 		4 PHE A 490
LEU A 298
ASP A 302
THR A 492
 None
 1.02A 1rmtD-4y23A:
undetectable		 1rmtD-4y23A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zlt C-C MOTIF CHEMOKINE
3

(Mus musculus) 		PF00048
(IL8) 		4 PHE F  41
LEU F  65
ASP F  64
THR F  43
 None
 0.95A 1rmtD-4zltF:
undetectable		 1rmtD-4zltF:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah1 TRIACYLGLYCEROL
LIPASE

(Clostridium
botulinum) 		no annotation 4 PHE A 329
TYR A 443
LEU A 447
THR A 226
 None
 1.06A 1rmtD-5ah1A:
undetectable		 1rmtD-5ah1A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4n F-BOX ONLY PROTEIN 2

(Mus musculus) 		PF04300
(FBA) 		4 ASP A 208
PHE A 271
LEU A 128
TRP A 140
 None
 1.02A 1rmtD-5b4nA:
undetectable		 1rmtD-5b4nA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq9 UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		PF12252
(SidE) 		4 ASP A 552
PHE A 568
LEU A 354
ASP A 351
 None
 1.03A 1rmtD-5bq9A:
undetectable		 1rmtD-5bq9A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu1 LPG1496

(Legionella
pneumophila) 		PF12252
(SidE) 		4 ASP A 552
PHE A 568
LEU A 354
ASP A 351
 None
 1.06A 1rmtD-5bu1A:
undetectable		 1rmtD-5bu1A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu2 LPG1496

(Legionella
pneumophila) 		PF12252
(SidE) 		4 ASP A 552
PHE A 568
LEU A 354
ASP A 351
 None
 1.03A 1rmtD-5bu2A:
undetectable		 1rmtD-5bu2A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bxg UNCHARACTERIZED
BETA-SANDWICH
PROTEIN

(Clostridioides
difficile) 		no annotation 4 PHE A 137
ASP A  70
THR A 135
TYR A  80
 None
 0.87A 1rmtD-5bxgA:
undetectable		 1rmtD-5bxgA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdh MAJOR ACID
PHOSPHATASE

(Legionella
pneumophila) 		PF00328
(His_Phos_2) 		4 TYR A 114
LEU A 113
THR A  91
TYR A 274
 None
 1.07A 1rmtD-5cdhA:
undetectable		 1rmtD-5cdhA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czz CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Staphylococcus
aureus) 		PF13395
(HNH_4)
PF16592
(Cas9_REC) 		4 PHE A 197
LEU A  71
THR A 200
TYR A 201
 None
 1.12A 1rmtD-5czzA:
undetectable		 1rmtD-5czzA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5egl ACYL COA HYDROLASE

(Staphylococcus
aureus) 		PF03061
(4HBT) 		4 ASP A  26
TYR A  80
LEU A  78
ASP A  76
 None
 0.98A 1rmtD-5eglA:
undetectable		 1rmtD-5eglA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eo9 DPR6, ISOFORM C

(Drosophila
melanogaster) 		PF07679
(I-set) 		4 ASP A 126
PHE A 129
ASP A 112
THR A 122
 None
 1.12A 1rmtD-5eo9A:
undetectable		 1rmtD-5eo9A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f05 PHI CLASS
GLUTATHIONE
TRANSFERASE GSTF5

(Populus
trichocarpa) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 ASP A 160
LEU A 151
THR A 163
TYR A 156
 None
 1.09A 1rmtD-5f05A:
undetectable		 1rmtD-5f05A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fl7 ATP SYNTHASE SUBUNIT
BETA

(Yarrowia
lipolytica) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 ASP D 380
LEU D 348
ASP D 346
THR D 363
 None
 0.86A 1rmtD-5fl7D:
undetectable		 1rmtD-5fl7D:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae) 		PF12717
(Cnd1) 		4 PHE A 197
TYR A 217
LEU A 221
ASP A 225
 None
 0.87A 1rmtD-5frsA:
undetectable		 1rmtD-5frsA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw7 GLUCOSIDASE YGJK

(Escherichia
coli) 		PF01204
(Trehalase) 		4 PHE A 691
TYR A 556
LEU A 394
TRP A 397
 None
 1.01A 1rmtD-5gw7A:
undetectable		 1rmtD-5gw7A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4k MANGANESE-BINDING
LIPOPROTEIN MNTA

(Listeria
monocytogenes) 		PF01297
(ZnuA) 		4 TYR A 177
LEU A 181
ASP A 185
THR A 292
 None
None
None
MN  A 502 ( 4.7A)
 1.04A 1rmtD-5i4kA:
undetectable		 1rmtD-5i4kA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldt MOMP PORIN

(Campylobacter
jejuni) 		PF05538
(Campylo_MOMP) 		5 PHE A 303
TYR A 276
LEU A 310
THR A 305
TYR A 304
 None
 1.39A 1rmtD-5ldtA:
undetectable		 1rmtD-5ldtA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lki TCDA1

(Photorhabdus
luminescens) 		PF03538
(VRP1) 		4 PHE A1110
TRP A1141
ASP A1127
TYR A1109
 None
 0.98A 1rmtD-5lkiA:
undetectable		 1rmtD-5lkiA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lol GLUTATHIONE
S-TRANSFERASE DHAR2

(Arabidopsis
thaliana) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 PHE A 141
TYR A 183
LEU A 187
THR A 148
 None
 1.04A 1rmtD-5lolA:
undetectable		 1rmtD-5lolA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m10 CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE

(Thermocrispum
municipale) 		PF07992
(Pyr_redox_2) 		4 PHE A 530
LEU A 414
TRP A 447
THR A 466
 None
 1.11A 1rmtD-5m10A:
undetectable		 1rmtD-5m10A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m8h ATP
PHOSPHORIBOSYLTRANSF
ERASE REGULATORY
SUBUNIT

(Psychrobacter
arcticus) 		PF13393
(tRNA-synt_His) 		4 PHE A 162
TYR A 183
LEU A 179
ASP A 175
 None
 1.11A 1rmtD-5m8hA:
undetectable		 1rmtD-5m8hA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd4 TUBULIN ALPHA CHAIN

(Bos taurus) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 PHE A 267
TYR A 432
LEU A 428
ASP A 424
 None
 1.04A 1rmtD-5nd4A:
undetectable		 1rmtD-5nd4A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5omc REPLICATION FACTOR A
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 PHE A  15
LEU A 120
ASP A  52
THR A 131
 None
 1.10A 1rmtD-5omcA:
undetectable		 1rmtD-5omcA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u56 STRINGENT STARVATION
PROTEIN A

(Francisella
tularensis) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		4 PHE C 142
TYR C 179
LEU C 183
THR C 149
 None
 0.90A 1rmtD-5u56C:
undetectable		 1rmtD-5u56C:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v10 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF03061
(4HBT) 		4 ASP A  20
PHE A  35
LEU A  80
ASP A  78
 None
 0.99A 1rmtD-5v10A:
undetectable		 1rmtD-5v10A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vcs ALPHA-1,6-MANNOSYL-G
LYCOPROTEIN
2-BETA-N-ACETYLGLUCO
SAMINYLTRANSFERASE

(Homo sapiens) 		no annotation 4 PHE A 338
LEU A 353
THR A 340
TYR A 341
 None
 1.03A 1rmtD-5vcsA:
undetectable		 1rmtD-5vcsA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z8l -

(-) 		no annotation 4 PHE A 113
ASP A 158
THR A 112
TYR A 116
 None
 1.07A 1rmtD-5z8lA:
undetectable		 1rmtD-5z8lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z8n -

(-) 		no annotation 4 PHE A 113
ASP A 158
THR A 112
TYR A 116
 None
 1.01A 1rmtD-5z8nA:
undetectable		 1rmtD-5z8nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zw4 PUTATIVE
O-METHYLTRANSFERASE
YRRM

(Bacillus
subtilis) 		no annotation 4 PHE A 143
TYR A 189
LEU A 193
TRP A 192
 None
 1.09A 1rmtD-5zw4A:
3.7		 1rmtD-5zw4A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ap4 DNA POLYMERASE III
SUBUNIT BETA

(Acinetobacter
baumannii) 		no annotation 4 PHE A 257
TYR A 158
LEU A 159
ASP A 177
 None
 1.07A 1rmtD-6ap4A:
undetectable		 1rmtD-6ap4A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bvg PROTEIN-N(PI)-PHOSPH
OHISTIDINE-SUGAR
PHOSPHOTRANSFERASE
(ENZYME II OF THE
PHOSPHOTRANSFERASE
SYSTEM) (PTS SYSTEM
GLUCOSE-SPECIFIC
IIBC COMPONENT)

(Bacillus cereus) 		no annotation 4 ASP A 413
TYR A 294
LEU A 298
TRP A 278
 None
 1.09A 1rmtD-6bvgA:
undetectable		 1rmtD-6bvgA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c2h CYSTATHIONINE
BETA-SYNTHASE

(Saccharomyces
cerevisiae) 		no annotation 4 ASP A 268
PHE A 272
LEU A 334
TRP A 333
 None
None
None
EDO  A 410 (-4.2A)
 0.93A 1rmtD-6c2hA:
2.3		 1rmtD-6c2hA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE

(Entamoeba
histolytica) 		no annotation 4 ASP A 256
PHE A 343
TYR A 350
LEU A 244
 EDO  A 610 (-3.3A)
None
None
None
 0.92A 1rmtD-6cc2A:
4.7		 1rmtD-6cc2A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eys -

(-) 		no annotation 4 TYR B 328
LEU B 332
TRP B 331
THR B 386
 None
 0.92A 1rmtD-6eysB:
undetectable		 1rmtD-6eysB:
undetectable