SIMILAR PATTERNS OF AMINO ACIDS FOR 1RMT_C_ADNC1503
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aoa | T-FIMBRIN (Homo sapiens) |
PF00307(CH) | 4 | PHE A 369LEU A 341GLY A 348ASP A 345 | PHE A 369 ( 1.3A)LEU A 341 ( 0.6A)GLY A 348 ( 0.0A)ASP A 345 ( 0.6A) | 1.02A | 1rmtC-1aoaA:undetectable | 1rmtC-1aoaA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1esc | ESTERASE (Streptomycesscabiei) |
PF13472(Lipase_GDSL_2) | 4 | PHE A 145LEU A 154TRP A 153GLY A 109 | None | 0.91A | 1rmtC-1escA:2.1 | 1rmtC-1escA:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ewx | TRYPAREDOXIN I (Crithidiafasciculata) |
PF13905(Thioredoxin_8) | 4 | PHE A 33LEU A 8GLY A 3ASP A 5 | NoneNoneACE A 1 (-4.2A)None | 0.96A | 1rmtC-1ewxA:undetectable | 1rmtC-1ewxA:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h0h | FORMATEDEHYDROGENASESUBUNIT ALPHA (Desulfovibriogigas) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 4 | PHE A 513TYR A 139LEU A 143TRP A 142 | None | 0.90A | 1rmtC-1h0hA:undetectable | 1rmtC-1h0hA:13.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i6q | LACTOFERRIN (Camelusdromedarius) |
PF00405(Transferrin) | 4 | ASP A 66TYR A 324LEU A 320GLY A 68 | None | 0.89A | 1rmtC-1i6qA:undetectable | 1rmtC-1i6qA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iou | YKT6P (Saccharomycescerevisiae) |
PF13774(Longin) | 4 | ASP A 112TYR A 101LEU A 19GLY A 12 | None | 0.93A | 1rmtC-1iouA:undetectable | 1rmtC-1iouA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j77 | HEMO (Neisseriameningitidis) |
PF01126(Heme_oxygenase) | 4 | ASP A 87LEU A 46GLY A 89TYR A 133 | None | 0.90A | 1rmtC-1j77A:undetectable | 1rmtC-1j77A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jed | SULFATEADENYLYLTRANSFERASE (Saccharomycescerevisiae) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 4 | TYR A 317LEU A 313GLY A 267ASP A 309 | NoneNoneNone NA A 522 (-2.4A) | 1.02A | 1rmtC-1jedA:2.2 | 1rmtC-1jedA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jjf | ENDO-1,4-BETA-XYLANASE Z (Ruminiclostridiumthermocellum) |
PF00756(Esterase) | 4 | ASP A 230TYR A 252LEU A 254GLY A 258 | None | 0.89A | 1rmtC-1jjfA:undetectable | 1rmtC-1jjfA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k9o | ALASERPIN (Manduca sexta) |
PF00079(Serpin) | 4 | PHE I 379LEU I 100GLY I 182ASP I 99 | None | 0.98A | 1rmtC-1k9oI:undetectable | 1rmtC-1k9oI:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kxh | ALPHA-AMYLASE (Pseudoalteromonashaloplanktis) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C) | 4 | ASP A 306PHE A 278GLY A 309TYR A 305 | None | 0.92A | 1rmtC-1kxhA:undetectable | 1rmtC-1kxhA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ldj | CULLIN HOMOLOG 1 (Homo sapiens) |
PF00888(Cullin)PF10557(Cullin_Nedd8) | 4 | ASP A 510TYR A 570GLY A 512ASP A 516 | None | 0.83A | 1rmtC-1ldjA:undetectable | 1rmtC-1ldjA:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lf9 | GLUCOAMYLASE (Thermoanaerobacteriumthermosaccharolyticum) |
PF00723(Glyco_hydro_15)PF09137(Glucodextran_N) | 4 | ASP A 566TYR A 574LEU A 598GLY A 570 | None | 0.86A | 1rmtC-1lf9A:undetectable | 1rmtC-1lf9A:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o5f | SERINE PROTEASEHEPSIN (Homo sapiens) |
PF00089(Trypsin) | 4 | PHE H 199LEU H 130GLY H 133ASP H 132 | None | 0.94A | 1rmtC-1o5fH:undetectable | 1rmtC-1o5fH:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r47 | ALPHA-GALACTOSIDASEA (Homo sapiens) |
PF16499(Melibiase_2)PF17450(Melibiase_2_C) | 4 | ASP A 155PHE A 159GLY A 147ASP A 136 | None | 0.99A | 1rmtC-1r47A:undetectable | 1rmtC-1r47A:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tz6 | PUTATIVE SUGARKINASE (Salmonellaenterica) |
PF00294(PfkB) | 4 | PHE A 66LEU A 53GLY A 11ASP A 108 | None | 0.96A | 1rmtC-1tz6A:3.1 | 1rmtC-1tz6A:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wy9 | ALLOGRAFTINFLAMMATORY FACTOR1 (Mus musculus) |
no annotation | 4 | PHE A 50TYR A 103LEU A 107GLY A 112 | None | 1.02A | 1rmtC-1wy9A:undetectable | 1rmtC-1wy9A:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2amc | PHENYLALANYL-TRNASYNTHETASE ALPHACHAINPHENYLALANYL-TRNASYNTHETASE BETACHAIN (Thermusthermophilus) |
PF01409(tRNA-synt_2d)PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 4 | PHE A 96TYR B 612LEU B 608GLY B 591 | None | 0.94A | 1rmtC-2amcA:undetectable | 1rmtC-2amcA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bi0 | HYPOTHETICAL PROTEINRV0216 (Mycobacteriumtuberculosis) |
no annotation | 4 | PHE A 150GLY A 79ASP A 75TYR A 94 | None | 0.87A | 1rmtC-2bi0A:undetectable | 1rmtC-2bi0A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c0y | PROCATHEPSIN S (Homo sapiens) |
PF00112(Peptidase_C1)PF08246(Inhibitor_I29) | 4 | ASP A 221TYR A 92LEU A 215GLY A 218 | None | 0.94A | 1rmtC-2c0yA:undetectable | 1rmtC-2c0yA:21.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2hf7 | CLASS B ACIDPHOSPHATASE (Escherichiacoli) |
PF03767(Acid_phosphat_B) | 8 | ASP A 46PHE A 56TYR A 70LEU A 71TRP A 77GLY A 113ASP A 145TYR A 193 | AF3 A 800 ( 3.7A)NoneNoneNoneNoneAF3 A 800 (-3.5A)NoneNone | 0.26A | 1rmtC-2hf7A:36.8 | 1rmtC-2hf7A:99.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2hf7 | CLASS B ACIDPHOSPHATASE (Escherichiacoli) |
PF03767(Acid_phosphat_B) | 5 | TYR A 70LEU A 71TRP A 77GLY A 144ASP A 145 | None | 1.17A | 1rmtC-2hf7A:36.8 | 1rmtC-2hf7A:99.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ibd | POSSIBLETRANSCRIPTIONALREGULATOR (Rhodococcusjostii) |
PF00440(TetR_N) | 4 | TYR A 112LEU A 70GLY A 75ASP A 71 | None | 0.98A | 1rmtC-2ibdA:undetectable | 1rmtC-2ibdA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nda | MID-CELL-ANCHOREDPROTEIN Z (Streptococcuspneumoniae) |
no annotation | 4 | TYR A 113LEU A 111GLY A 104ASP A 109 | None | 1.03A | 1rmtC-2ndaA:undetectable | 1rmtC-2ndaA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oq1 | TYROSINE-PROTEINKINASE ZAP-70 (Homo sapiens) |
PF00017(SH2) | 4 | TYR A 180GLY A 187ASP A 186TYR A 211 | None | 0.97A | 1rmtC-2oq1A:undetectable | 1rmtC-2oq1A:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p6r | AFUHEL308 HELICASE (Archaeoglobusfulgidus) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | ASP A 489LEU A 462TRP A 465GLY A 493 | None | 0.87A | 1rmtC-2p6rA:undetectable | 1rmtC-2p6rA:14.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbh | PROCATHEPSIN B (Homo sapiens) |
PF00112(Peptidase_C1)PF08127(Propeptide_C1) | 4 | PHE A 5TRP A 11GLY A 168ASP A 40 | None | 1.00A | 1rmtC-2pbhA:undetectable | 1rmtC-2pbhA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5k | MAJOR CAPSID PROTEINL1 (Alphapapillomavirus10) |
PF00500(Late_protein_L1) | 4 | PHE A 70LEU A 41GLY A 105ASP A 367 | None | 0.96A | 1rmtC-2r5kA:undetectable | 1rmtC-2r5kA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w8z | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING (Geobacillusstearothermophilus) |
PF00393(6PGD)PF03446(NAD_binding_2) | 4 | PHE A 156LEU A 71GLY A 124ASP A 99 | None | 0.99A | 1rmtC-2w8zA:4.3 | 1rmtC-2w8zA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wgy | CYTOCHROME P450 130 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | PHE A 236LEU A 156GLY A 107ASP A 211 | None | 1.00A | 1rmtC-2wgyA:undetectable | 1rmtC-2wgyA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ww8 | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcuspneumoniae) |
PF13519(VWA_2) | 4 | ASP A 533LEU A 370GLY A 531ASP A 530 | NoneNoneNone CA A1001 (-2.9A) | 0.92A | 1rmtC-2ww8A:3.1 | 1rmtC-2ww8A:13.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xpi | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT CUT9 (Schizosaccharomycespombe) |
PF12895(ANAPC3)PF13181(TPR_8)PF13424(TPR_12) | 4 | TYR A 127LEU A 123GLY A 115ASP A 119 | None | 1.03A | 1rmtC-2xpiA:undetectable | 1rmtC-2xpiA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y9y | ISWI ONE COMPLEXPROTEIN 3 (Saccharomycescerevisiae) |
PF15612(WHIM1) | 4 | PHE B 241LEU B 236GLY B 229ASP B 232 | None | 0.97A | 1rmtC-2y9yB:undetectable | 1rmtC-2y9yB:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z23 | PERIPLASMICOLIGOPEPTIDE-BINDINGPROTEIN (Yersinia pestis) |
PF00496(SBP_bac_5) | 4 | TYR A 321GLY A 500ASP A 502TYR A 269 | None | 0.99A | 1rmtC-2z23A:undetectable | 1rmtC-2z23A:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a21 | PUTATIVE SECRETEDALPHA-GALACTOSIDASE (Streptomycesavermitilis) |
PF00652(Ricin_B_lectin)PF16499(Melibiase_2) | 4 | ASP A 171PHE A 175GLY A 163ASP A 142 | None | 0.90A | 1rmtC-3a21A:undetectable | 1rmtC-3a21A:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d46 | PUTATIVE GALACTONATEDEHYDRATASE (Salmonellaenterica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASP A 146PHE A 83LEU A 368GLY A 390 | None | 1.00A | 1rmtC-3d46A:undetectable | 1rmtC-3d46A:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e8s | PUTATIVE SAMDEPENDENTMETHYLTRANSFERASE (Pseudomonasputida) |
PF13489(Methyltransf_23) | 4 | ASP A 161GLY A 165ASP A 164TYR A 162 | None | 1.02A | 1rmtC-3e8sA:2.8 | 1rmtC-3e8sA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ezz | DUAL SPECIFICITYPROTEIN PHOSPHATASE4 (Homo sapiens) |
PF00782(DSPc) | 4 | ASP A 218TYR A 242LEU A 225GLY A 221 | None | 0.96A | 1rmtC-3ezzA:undetectable | 1rmtC-3ezzA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fnr | ARGINYL-TRNASYNTHETASE (Campylobacterjejuni) |
PF00750(tRNA-synt_1d)PF05746(DALR_1) | 4 | PHE A 333LEU A 271GLY A 277ASP A 278 | None | 1.01A | 1rmtC-3fnrA:undetectable | 1rmtC-3fnrA:18.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h2i | ESTERASE (Xanthomonasoryzae) |
PF03583(LIP) | 4 | PHE A 269LEU A 275GLY A 231TYR A 138 | None | 0.90A | 1rmtC-3h2iA:undetectable | 1rmtC-3h2iA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 3 (Thermusthermophilus) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4)PF10588(NADH-G_4Fe-4S_3)PF13510(Fer2_4) | 4 | LEU 3 602TRP 3 322GLY 3 636TYR 3 567 | None | 0.87A | 1rmtC-3i9v3:2.6 | 1rmtC-3i9v3:12.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jcu | CHLOROPHYLL A-BBINDING PROTEIN,CHLOROPLASTIC (Spinaciaoleracea) |
PF00504(Chloroa_b-bind) | 4 | PHE G 58TYR G 35LEU G 36GLY G 42 | CLA G 602 ( 4.9A)NoneCLA G 602 (-4.1A)CLA G 602 (-4.4A) | 1.01A | 1rmtC-3jcuG:undetectable | 1rmtC-3jcuG:25.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kkj | AMINE OXIDASE,FLAVIN-CONTAINING (Pseudomonassyringae groupgenomosp. 3) |
PF01593(Amino_oxidase)PF13450(NAD_binding_8) | 4 | PHE A 270LEU A 226GLY A 49ASP A 223 | None | 0.85A | 1rmtC-3kkjA:undetectable | 1rmtC-3kkjA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ldg | PUTATIVEUNCHARACTERIZEDPROTEIN SMU.472 (Streptococcusmutans) |
PF01170(UPF0020)PF02926(THUMP) | 4 | PHE A 295LEU A 304GLY A 261ASP A 200 | None | 0.99A | 1rmtC-3ldgA:2.2 | 1rmtC-3ldgA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ntv | MW1564 PROTEIN (Staphylococcusaureus) |
PF01596(Methyltransf_3) | 4 | PHE A 159TYR A 204LEU A 208GLY A 213 | None | 0.93A | 1rmtC-3ntvA:4.3 | 1rmtC-3ntvA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oeb | S-LAYER ASSOCIATEDMULTIDOMAINENDOGLUCANASE (Caldanaerobiuspolysaccharolyticus) |
PF02018(CBM_4_9) | 4 | PHE A 10LEU A 14GLY A 48ASP A 19 | None | 0.84A | 1rmtC-3oebA:undetectable | 1rmtC-3oebA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s5k | FALCILYSIN (Plasmodiumfalciparum) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C)PF08367(M16C_assoc) | 4 | PHE A 640TYR A 144GLY A 186ASP A 190 | None | 0.98A | 1rmtC-3s5kA:undetectable | 1rmtC-3s5kA:10.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t2n | SERINE PROTEASEHEPSIN (Homo sapiens) |
PF00089(Trypsin)PF09272(Hepsin-SRCR) | 4 | PHE A 357LEU A 285GLY A 288ASP A 287 | None | 1.02A | 1rmtC-3t2nA:undetectable | 1rmtC-3t2nA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tlz | MCCF (Escherichiacoli) |
PF02016(Peptidase_S66) | 4 | PHE A 22LEU A 123GLY A 91ASP A 119 | NoneNoneAMP A 500 (-3.2A)None | 1.00A | 1rmtC-3tlzA:undetectable | 1rmtC-3tlzA:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3voh | CELLOBIOHYDROLASE (Coprinopsiscinerea) |
PF01341(Glyco_hydro_6) | 4 | ASP A 132TYR A 187LEU A 191GLY A 134 | None | 0.90A | 1rmtC-3vohA:undetectable | 1rmtC-3vohA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9a | PUTATIVEUNCHARACTERIZEDPROTEIN (Coprinopsiscinerea) |
no annotation | 4 | PHE A 177LEU A 190TRP A 165GLY A 156 | None | 0.99A | 1rmtC-3w9aA:undetectable | 1rmtC-3w9aA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wdq | BETA-MANNANASE (Symbioticprotist ofReticulitermessperatus) |
PF02156(Glyco_hydro_26) | 4 | TYR A 308LEU A 54GLY A 57ASP A 58 | None | 1.01A | 1rmtC-3wdqA:undetectable | 1rmtC-3wdqA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b52 | BACILLOLYSIN (Paenibacilluspolymyxa) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C) | 4 | PHE A 269TYR A 205LEU A 208GLY A 217 | None | 0.86A | 1rmtC-4b52A:undetectable | 1rmtC-4b52A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3z | MULTIDRUGRESISTANCE-ASSOCIATED PROTEIN 1 (Homo sapiens) |
PF00005(ABC_tran) | 4 | TYR A 852LEU A 856GLY A 860ASP A 859 | None | 0.99A | 1rmtC-4c3zA:undetectable | 1rmtC-4c3zA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7g | BETA-N-ACETYLHEXOSAMINIDASE (Streptomycescoelicolor) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b) | 5 | ASP A 441PHE A 445TYR A 168LEU A 167ASP A 163 | None | 1.37A | 1rmtC-4c7gA:undetectable | 1rmtC-4c7gA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6e | SUPEROXIDE DISMUTASE[MN], MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | LEU A 7TRP A 9GLY A 12ASP A 10 | MLY A 8 ( 4.0A)MLY A 8 ( 4.7A)NoneNone | 0.95A | 1rmtC-4f6eA:undetectable | 1rmtC-4f6eA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h79 | CRISPR-ASSOCIATEDPROTEIN, CSE2 FAMILY (Thermobifidafusca) |
PF09485(CRISPR_Cse2) | 4 | ASP A 64PHE A 18GLY A 60TYR A 68 | None | 0.83A | 1rmtC-4h79A:undetectable | 1rmtC-4h79A:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i6v | AMIDOHYDROLASE 2 (Planctopiruslimnophila) |
PF02614(UxaC) | 4 | PHE A 380TYR A 46GLY A 39TYR A 376 | NoneGOL A 503 (-4.4A)NoneNone | 0.92A | 1rmtC-4i6vA:undetectable | 1rmtC-4i6vA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ipb | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF11396(PepSY_like) | 4 | PHE A 93TYR A 135LEU A 133GLY A 123 | None | 0.80A | 1rmtC-4ipbA:undetectable | 1rmtC-4ipbA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l83 | UBE2I2 PROTEIN (Brugia malayi) |
PF00179(UQ_con) | 4 | ASP A 67PHE A 40LEU A 10GLY A 4 | None | 0.93A | 1rmtC-4l83A:undetectable | 1rmtC-4l83A:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7s | BTRN (Bacilluscirculans) |
PF13186(SPASM) | 4 | PHE A 59LEU A 71GLY A 76ASP A 72 | None | 0.96A | 1rmtC-4m7sA:2.4 | 1rmtC-4m7sA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nzj | PUTATIVEALPHA-GALACTOSIDASE (Bacteroidesfragilis) |
PF05345(He_PIG)PF10632(He_PIG_assoc)PF16499(Melibiase_2) | 4 | ASP A 228PHE A 232GLY A 220ASP A 209 | None | 0.98A | 1rmtC-4nzjA:undetectable | 1rmtC-4nzjA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ogz | PUTATIVEALPHA-GALACTOSIDASE/MELIBIASE (Bacteroidesfragilis) |
PF10632(He_PIG_assoc)PF16499(Melibiase_2)PF17450(Melibiase_2_C) | 4 | ASP A 228PHE A 232GLY A 220ASP A 209 | None | 0.99A | 1rmtC-4ogzA:undetectable | 1rmtC-4ogzA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovy | HALOACIDDEHALOGENASE DOMAINPROTEIN HYDROLASE (Planctopiruslimnophila) |
PF12710(HAD) | 4 | ASP A 65TYR A 291GLY A 260ASP A 259 | CA A 409 (-3.0A)NoneNoneNone | 0.86A | 1rmtC-4ovyA:10.3 | 1rmtC-4ovyA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pui | SUFE-LIKE PROTEIN,CHLOROPLASTIC (Arabidopsisthaliana) |
PF01722(BolA) | 4 | ASP A 302PHE A 325LEU A 358GLY A 321 | None | 0.98A | 1rmtC-4puiA:undetectable | 1rmtC-4puiA:25.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q85 | RIBOSOMAL PROTEINS12METHYLTHIOTRANSFERASE ACCESSORY FACTORYCAO (Escherichiacoli) |
PF02624(YcaO) | 4 | ASP A 143TYR A 573LEU A 91GLY A 147 | None | 0.99A | 1rmtC-4q85A:undetectable | 1rmtC-4q85A:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qti | UROKINASEPLASMINOGENACTIVATOR SURFACERECEPTOR (Homo sapiens) |
PF00021(UPAR_LY6) | 4 | TYR U 195LEU U 212GLY U 191ASP U 214 | None | 1.02A | 1rmtC-4qtiU:undetectable | 1rmtC-4qtiU:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r04 | TOXIN A (Clostridioidesdifficile) |
PF11713(Peptidase_C80)PF12918(TcdB_N)PF12919(TcdA_TcdB)PF12920(TcdA_TcdB_pore) | 4 | ASP A1784TYR A1792LEU A1788ASP A1781 | None | 0.77A | 1rmtC-4r04A:undetectable | 1rmtC-4r04A:8.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u5w | TYROSINE-PROTEINKINASE HCK (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1) | 4 | ASP B 176PHE B 149LEU B 223GLY B 182 | None | 1.02A | 1rmtC-4u5wB:undetectable | 1rmtC-4u5wB:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8l | ENDO-1,4-BETA-XYLANASE C (Paenibacillusbarcinonensis) |
PF00331(Glyco_hydro_10) | 4 | TYR A 515LEU A 511GLY A 497ASP A 507 | NoneNoneNone CA A1101 (-2.2A) | 0.91A | 1rmtC-4w8lA:undetectable | 1rmtC-4w8lA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wz9 | AGAP004809-PA (Anophelesgambiae) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | ASP A 401TYR A 670LEU A 723GLY A 406 | None | 1.02A | 1rmtC-4wz9A:undetectable | 1rmtC-4wz9A:12.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x00 | PUTATIVE HYDROLASE (Burkholderiacenocepacia) |
PF12697(Abhydrolase_6) | 4 | PHE A 269TYR A 254LEU A 225GLY A 110 | NoneEDO A 304 (-4.6A)NoneNone | 0.99A | 1rmtC-4x00A:undetectable | 1rmtC-4x00A:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzg | PROTEIN PHOSPHATASE2C 57 (Arabidopsisthaliana) |
PF00481(PP2C) | 4 | LEU A 149TRP A 148GLY A 153ASP A 154 | None | 1.00A | 1rmtC-4yzgA:undetectable | 1rmtC-4yzgA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z45 | ODORANT-BINDINGPROTEIN NRIBOBP3 (Nasonoviaribisnigri) |
PF01395(PBP_GOBP) | 4 | PHE A 5TRP A 71GLY A 66TYR A 13 | None | 0.86A | 1rmtC-4z45A:undetectable | 1rmtC-4z45A:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dds | CRMG (Actinoalloteichussp. WH1-2216-6) |
PF00202(Aminotran_3) | 4 | PHE A 60TYR A 492LEU A 491GLY A 322 | NoneGOL A 602 ( 4.0A)NoneNone | 1.01A | 1rmtC-5ddsA:2.4 | 1rmtC-5ddsA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dk6 | 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE (Colwelliapsychrerythraea) |
PF01048(PNP_UDP_1) | 4 | ASP A 42LEU A 232GLY A 40ASP A 39 | None | 1.02A | 1rmtC-5dk6A:undetectable | 1rmtC-5dk6A:24.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e57 | TRANSCRIPTIONREGULATOR AMTR (Mycolicibacteriumsmegmatis) |
PF00440(TetR_N) | 4 | ASP A 49TYR A 59LEU A 58GLY A 52 | None | 1.01A | 1rmtC-5e57A:undetectable | 1rmtC-5e57A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5egl | ACYL COA HYDROLASE (Staphylococcusaureus) |
PF03061(4HBT) | 4 | ASP A 26TYR A 80LEU A 78ASP A 76 | None | 1.02A | 1rmtC-5eglA:undetectable | 1rmtC-5eglA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5frs | SISTER CHROMATIDCOHESION PROTEINPDS5 (Saccharomycescerevisiae) |
PF12717(Cnd1) | 4 | PHE A 197TYR A 217LEU A 221ASP A 225 | None | 0.89A | 1rmtC-5frsA:undetectable | 1rmtC-5frsA:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hei | NFRA2 (Bacillusmegaterium) |
PF00881(Nitroreductase) | 4 | PHE A 83LEU A 97GLY A 102ASP A 101 | None | 0.93A | 1rmtC-5heiA:undetectable | 1rmtC-5heiA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hyz | GRAS FAMILYTRANSCRIPTION FACTORCONTAINING PROTEIN,EXPRESSED (Oryza sativa) |
PF03514(GRAS) | 4 | TYR A 445LEU A 412GLY A 320TYR A 283 | None | 1.02A | 1rmtC-5hyzA:2.9 | 1rmtC-5hyzA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i08 | SPIKE GLYCOPROTEIN,ENVELOPEGLYCOPROTEIN CHIMERA (HumancoronavirusHKU1;Humanimmunodeficiencyvirus 1) |
PF01601(Corona_S2)PF09408(Spike_rec_bind)PF16451(Spike_NTD) | 4 | ASP A 623GLY A 380ASP A 606TYR A 609 | None | 0.97A | 1rmtC-5i08A:undetectable | 1rmtC-5i08A:9.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l37 | MSM0273 (Mycolicibacteriumsmegmatis) |
PF03319(EutN_CcmL) | 4 | PHE A 62LEU A 72GLY A 22ASP A 40 | None | 0.90A | 1rmtC-5l37A:undetectable | 1rmtC-5l37A:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9w | ACETOPHENONECARBOXYLASE BETASUBUNITACETOPHENONECARBOXYLASE DELTASUBUNIT (Aromatoleumaromaticum) |
PF02538(Hydantoinase_B)PF08882(Acetone_carb_G) | 4 | PHE C 7LEU C 104GLY A 259ASP A 258 | None | 0.99A | 1rmtC-5l9wC:undetectable | 1rmtC-5l9wC:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9w | ACETOPHENONECARBOXYLASE DELTASUBUNIT (Aromatoleumaromaticum) |
PF02538(Hydantoinase_B) | 4 | TYR A 134LEU A 139GLY A 75ASP A 74 | None | 0.94A | 1rmtC-5l9wA:undetectable | 1rmtC-5l9wA:14.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lhs | UROKINASE-TYPEPLASMINOGENACTIVATOR (Mus musculus) |
no annotation | 4 | PHE B 40LEU B 155TRP B 215GLY B 44 | None | 0.97A | 1rmtC-5lhsB:undetectable | 1rmtC-5lhsB:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lki | TCDA1 (Photorhabdusluminescens) |
PF03538(VRP1) | 4 | PHE A1110TRP A1141ASP A1127TYR A1109 | None | 0.94A | 1rmtC-5lkiA:undetectable | 1rmtC-5lkiA:6.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ln4 | PH 6 ANTIGEN,PH 6ANTIGEN (Yersinia pestis) |
no annotation | 4 | PHE A 110LEU A 67TRP A 81GLY A 54 | None | 0.87A | 1rmtC-5ln4A:undetectable | 1rmtC-5ln4A:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lo7 | FIMBRIAL PROTEINMYFA,FIMBRIALPROTEIN MYFA (Yersiniaenterocolitica) |
no annotation | 4 | PHE A 113LEU A 73TRP A 85GLY A 60 | None | 0.87A | 1rmtC-5lo7A:undetectable | 1rmtC-5lo7A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mac | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE-OXYGENASE TYPE III (Methanococcoidesburtonii) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | ASP A 26LEU A 34TRP A 131GLY A 30 | None | 0.98A | 1rmtC-5macA:undetectable | 1rmtC-5macA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mdx | CHLOROPHYLL A-BBINDING PROTEIN 1,CHLOROPLASTIC (Arabidopsisthaliana) |
no annotation | 4 | PHE G 92TYR G 69LEU G 70GLY G 76 | CLA G 602 (-4.5A)NoneCLA G 602 (-4.1A)CLA G 602 (-4.8A) | 0.93A | 1rmtC-5mdxG:undetectable | 1rmtC-5mdxG:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojs | TRANSCRIPTION-ASSOCIATED PROTEIN 1 (Saccharomycescerevisiae) |
PF00454(PI3_PI4_kinase)PF02259(FAT) | 4 | PHE T3557LEU T3645GLY T3707TYR T3560 | None | 1.03A | 1rmtC-5ojsT:undetectable | 1rmtC-5ojsT:4.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT BTUNGSTEN-CONTAININGFORMYLMETHANOFURANDEHYDROGENASE 2SUBUNIT C (Methanothermobactersp. CaT2;Methanothermobacterwolfeii) |
PF00384(Molybdopterin)PF01493(GXGXG) | 4 | PHE C 218TYR B 224LEU B 223GLY C 247 | None | 0.80A | 1rmtC-5t5iC:undetectable | 1rmtC-5t5iC:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ucd | NAD(P)-DEPENDENTBENZALDEHYDEDEHYDROGENASE (Pseudomonasputida) |
PF00171(Aldedh) | 4 | PHE A 119LEU A 57GLY A 246TYR A 121 | NAP A 501 (-4.5A)NoneNoneZBZ A 249 ( 4.0A) | 0.84A | 1rmtC-5ucdA:3.9 | 1rmtC-5ucdA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vft | 26S PROTEASOMEREGULATORY SUBUNIT 8 (Homo sapiens) |
no annotation | 4 | ASP C 119LEU C 116GLY C 70TYR C 121 | None | 0.98A | 1rmtC-5vftC:undetectable | 1rmtC-5vftC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y9c | MAJOR CAPSID PROTEINL1 (Alphapapillomavirus9) |
no annotation | 4 | PHE A 74LEU A 42GLY A 109ASP A 370 | None | 0.88A | 1rmtC-5y9cA:undetectable | 1rmtC-5y9cA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zji | CHLOROPHYLL A-BBINDING PROTEIN,CHLOROPLASTIC (Zea mays) |
no annotation | 4 | PHE Y 54TYR Y 31LEU Y 32GLY Y 38 | CLA Y 602 (-4.7A)NoneCLA Y 602 (-4.0A)CLA Y 602 (-4.5A) | 1.00A | 1rmtC-5zjiY:undetectable | 1rmtC-5zjiY:16.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6apx | MALTOSE-BINDINGPERIPLASMICPROTEIN,DUALSPECIFICITY PROTEINPHOSPHATASE 1 (Escherichiacoli;Homo sapiens) |
no annotation | 4 | ASP A1196TYR A1220LEU A1203GLY A1199 | None | 0.94A | 1rmtC-6apxA:undetectable | 1rmtC-6apxA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cc2 | CELL DIVISIONCONTROL PROTEIN 45CDC45 PUTATIVE (Entamoebahistolytica) |
no annotation | 4 | ASP A 256PHE A 343TYR A 350LEU A 244 | EDO A 610 (-3.3A)NoneNoneNone | 0.92A | 1rmtC-6cc2A:undetectable | 1rmtC-6cc2A:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eom | MUTT/NUDIX FAMILYPROTEIN (Caldithrixabyssi) |
no annotation | 4 | ASP A 416PHE A 444TYR A 477GLY A 463 | None | 0.99A | 1rmtC-6eomA:undetectable | 1rmtC-6eomA:13.74 |