SIMILAR PATTERNS OF AMINO ACIDS FOR 1RMT_B_ADNB1502_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a2v METHYLAMINE OXIDASE

(Ogataea angusta) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 GLU A 274
TYR A 581
LEU A 580
THR A  55
 None
 1.13A 1rmtB-1a2vA:
undetectable		 1rmtB-1a2vA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8a PROTEIN
(ASPARTYL-TRNA
SYNTHETASE)

(Thermococcus
kodakarensis) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 PHE A 389
GLU A 196
TYR A 392
LEU A 193
 None
 1.08A 1rmtB-1b8aA:
undetectable		 1rmtB-1b8aA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bam ENDONUCLEASE BAMH I

(Bacillus
amyloliquefaciens) 		PF02923
(BamHI) 		4 PHE A 174
LEU A 131
THR A   9
LYS A  13
 None
 1.21A 1rmtB-1bamA:
undetectable		 1rmtB-1bamA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bwd PROTEIN
(INOSAMINE-PHOSPHATE
AMIDINOTRANSFERASE)

(Streptomyces
griseus) 		no annotation 4 GLU A 140
TYR A 141
LEU A 137
THR A  78
 None
 1.23A 1rmtB-1bwdA:
undetectable		 1rmtB-1bwdA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eo8 ANTIBODY (HEAVY
CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 PHE H 146
LEU H 170
THR H 117
TYR H 145
 None
 1.26A 1rmtB-1eo8H:
undetectable		 1rmtB-1eo8H:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lla HEMOCYANIN (SUBUNIT
TYPE II)

(Limulus
polyphemus) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 PHE A 626
GLU A 214
TYR A 162
LEU A 436
 None
 1.23A 1rmtB-1llaA:
undetectable		 1rmtB-1llaA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m6y S-ADENOSYL-METHYLTRA
NSFERASE MRAW

(Thermotoga
maritima) 		PF01795
(Methyltransf_5) 		4 GLU A 121
TYR A   4
LEU A 111
THR A 205
 None
 1.16A 1rmtB-1m6yA:
4.4		 1rmtB-1m6yA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n02 CYANOVIRIN-N

(Nostoc
ellipsosporum) 		PF08881
(CVNH) 		4 PHE A   4
LEU A  98
THR A   7
LYS A  24
 None
 1.10A 1rmtB-1n02A:
undetectable		 1rmtB-1n02A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus) 		PF00028
(Cadherin) 		4 PHE A  51
GLU A  13
LEU A  66
LYS A   8
 None
 0.94A 1rmtB-1q5aA:
undetectable		 1rmtB-1q5aA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1re5 3-CARBOXY-CIS,CIS-MU
CONATE
CYCLOISOMERASE

(Pseudomonas
putida) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 PHE A 192
GLU A  32
LEU A  35
THR A 105
 None
 1.07A 1rmtB-1re5A:
undetectable		 1rmtB-1re5A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3i PROBABLE CYSTEINE
DESULFURASE

(Synechocystis
sp.) 		PF00266
(Aminotran_5) 		4 PHE A 240
LEU A 291
THR A  96
TYR A  95
 None
 1.16A 1rmtB-1t3iA:
3.5		 1rmtB-1t3iA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tvp CELLULASE

(Pseudoalteromonas
haloplanktis) 		PF00150
(Cellulase) 		4 PHE A  38
LEU A 258
THR A  40
TYR A  39
 None
 1.10A 1rmtB-1tvpA:
undetectable		 1rmtB-1tvpA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txk GLUCANS BIOSYNTHESIS
PROTEIN G

(Escherichia
coli) 		PF04349
(MdoG) 		4 PHE A 310
LEU A 250
THR A 338
TYR A 383
 None
 1.13A 1rmtB-1txkA:
undetectable		 1rmtB-1txkA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ug3 EUKARYOTIC PROTEIN
SYNTHESIS INITIATION
FACTOR 4G

(Homo sapiens) 		PF02020
(W2)
PF02847
(MA3) 		4 PHE A1360
GLU A1406
LEU A1402
THR A1364
 None
 1.14A 1rmtB-1ug3A:
undetectable		 1rmtB-1ug3A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v8b ADENOSYLHOMOCYSTEINA
SE

(Plasmodium
falciparum) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 PHE A 172
GLU A 115
LEU A 141
THR A 174
LYS A 177
 None
 1.43A 1rmtB-1v8bA:
3.2		 1rmtB-1v8bA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w25 STALKED-CELL
DIFFERENTIATION
CONTROLLING PROTEIN

(Caulobacter
vibrioides) 		PF00072
(Response_reg)
PF00990
(GGDEF) 		4 PHE A  62
LEU A  81
THR A  63
LYS A  67
 None
 1.16A 1rmtB-1w25A:
4.3		 1rmtB-1w25A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y0h HYPOTHETICAL PROTEIN
RV0793

(Mycobacterium
tuberculosis) 		PF03992
(ABM) 		4 GLU A  57
TYR A  59
LEU A  65
TYR A  74
 ACT  A 301 (-2.9A)
None
None
ACT  A 303 (-4.7A)
 1.23A 1rmtB-1y0hA:
undetectable		 1rmtB-1y0hA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zpu IRON TRANSPORT
MULTICOPPER OXIDASE
FET3

(Saccharomyces
cerevisiae) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 PHE A 148
GLU A 155
TYR A 152
LEU A 210
 None
BMA  A3001 (-4.2A)
None
None
 0.86A 1rmtB-1zpuA:
undetectable		 1rmtB-1zpuA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a3l AMP DEAMINASE

(Arabidopsis
thaliana) 		PF00962
(A_deaminase) 		4 PHE A 328
TYR A 261
LEU A 674
THR A 330
 None
 1.11A 1rmtB-2a3lA:
undetectable		 1rmtB-2a3lA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abj BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE,
CYTOSOLIC

(Homo sapiens) 		PF01063
(Aminotran_4) 		4 PHE A 130
LEU A 181
THR A  22
LYS A  24
 None
 1.23A 1rmtB-2abjA:
undetectable		 1rmtB-2abjA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2drq XYLANASE Y

(Bacillus
halodurans) 		PF01270
(Glyco_hydro_8) 		4 GLU A 130
LEU A 161
THR A  95
TYR A 100
 None
 1.18A 1rmtB-2drqA:
undetectable		 1rmtB-2drqA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2drq XYLANASE Y

(Bacillus
halodurans) 		PF01270
(Glyco_hydro_8) 		4 PHE A 260
TYR A 265
LEU A 323
TYR A 306
 None
 1.18A 1rmtB-2drqA:
undetectable		 1rmtB-2drqA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fel 3-CARBOXY-CIS,CIS-MU
CONATE LACTONIZING
ENZYME

(Agrobacterium
tumefaciens) 		PF00206
(Lyase_1) 		4 PHE A 194
GLU A  37
LEU A  40
THR A 107
 None
 1.13A 1rmtB-2felA:
undetectable		 1rmtB-2felA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h56 DNA-3-METHYLADENINE
GLYCOSIDASE

(Bacillus
halodurans) 		PF00730
(HhH-GPD) 		4 PHE A 145
LEU A 195
THR A  35
LYS A   0
 None
 1.15A 1rmtB-2h56A:
undetectable		 1rmtB-2h56A:
21.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hf7 CLASS B ACID
PHOSPHATASE

(Escherichia
coli) 		PF03767
(Acid_phosphat_B) 		7 PHE A  56
GLU A  68
TYR A  70
LEU A  71
THR A 192
TYR A 193
LYS A 194
 None
 0.41A 1rmtB-2hf7A:
34.1		 1rmtB-2hf7A:
99.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf7 STRICTOSIDINE-O-BETA
-D-GLUCOSIDASE

(Rauvolfia
serpentina) 		PF00232
(Glyco_hydro_1) 		4 PHE A 175
GLU A 169
LEU A 164
TYR A 172
 None
 1.21A 1rmtB-2jf7A:
1.8		 1rmtB-2jf7A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mpa MN12H2
IGG2A-KAPPA,HEAVY
CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 PHE H 154
LEU H 178
THR H 125
TYR H 153
 None
 1.24A 1rmtB-2mpaH:
undetectable		 1rmtB-2mpaH:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2np3 PUTATIVE TETR-FAMILY
REGULATOR

(Streptomyces
coelicolor) 		PF00440
(TetR_N) 		4 GLU A  83
LEU A 124
THR A  37
LYS A  35
 None
 1.16A 1rmtB-2np3A:
undetectable		 1rmtB-2np3A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o3i HYPOTHETICAL PROTEIN

(Chromobacterium
violaceum) 		PF06032
(DUF917) 		4 LEU A  10
THR A  46
TYR A  44
LYS A  40
 None
 1.21A 1rmtB-2o3iA:
undetectable		 1rmtB-2o3iA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rkv TRICHOTHECENE
3-O-ACETYLTRANSFERAS
E

(Fusarium
graminearum) 		PF02458
(Transferase) 		4 PHE A 390
TYR A  27
LEU A  25
TYR A 388
 None
 1.25A 1rmtB-2rkvA:
undetectable		 1rmtB-2rkvA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wiz ARCHAEAL HJC

(Archaeoglobus
fulgidus) 		PF01870
(Hjc) 		4 PHE A  94
GLU A  80
TYR A  82
LEU A  48
 None
 1.12A 1rmtB-2wizA:
undetectable		 1rmtB-2wizA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wmo DEDICATOR OF
CYTOKINESIS PROTEIN
9

(Homo sapiens) 		PF06920
(DHR-2) 		4 PHE A 358
LEU A 375
TYR A 354
LYS A 349
 None
 1.20A 1rmtB-2wmoA:
undetectable		 1rmtB-2wmoA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wn2 DISCOIDIN-1 SUBUNIT
A

(Dictyostelium
discoideum) 		PF00754
(F5_F8_type_C)
PF09458
(H_lectin) 		4 PHE A 149
LEU A  10
THR A 151
TYR A 150
 None
 1.09A 1rmtB-2wn2A:
undetectable		 1rmtB-2wn2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zba TRICHOTHECENE
3-O-ACETYLTRANSFERAS
E

(Fusarium
sporotrichioides) 		PF02458
(Transferase) 		4 PHE A 398
TYR A  36
LEU A  34
TYR A 396
 None
 1.26A 1rmtB-2zbaA:
undetectable		 1rmtB-2zbaA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3akf PUTATIVE SECRETED
ALPHA
L-ARABINOFURANOSIDAS
E II

(Streptomyces
avermitilis) 		PF04616
(Glyco_hydro_43)
PF05270
(AbfB) 		4 GLU A 267
TYR A  31
LEU A  51
LYS A 270
 None
 1.19A 1rmtB-3akfA:
undetectable		 1rmtB-3akfA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e7h DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Vibrio cholerae) 		no annotation 4 TYR A  74
LEU A  19
THR A  25
LYS A  38
 None
 0.85A 1rmtB-3e7hA:
undetectable		 1rmtB-3e7hA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eyf AD-2

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU B  81
THR B  61
TYR B  60
LYS B  65
 None
 1.00A 1rmtB-3eyfB:
undetectable		 1rmtB-3eyfB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpz THIAZOLE
BIOSYNTHETIC ENZYME

(Saccharomyces
cerevisiae) 		PF01946
(Thi4) 		4 PHE A 165
TYR A  56
LEU A  60
THR A 168
 None
 1.23A 1rmtB-3fpzA:
undetectable		 1rmtB-3fpzA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g1n E3 UBIQUITIN-PROTEIN
LIGASE HUWE1

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A4128
TYR A4133
THR A4090
TYR A4127
 None
 1.14A 1rmtB-3g1nA:
undetectable		 1rmtB-3g1nA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gle PILIN

(Streptococcus
pyogenes) 		PF12892
(FctA) 		4 GLU A 117
TYR A 128
THR A  50
TYR A  83
 GLU  A 117 ( 0.6A)
TYR  A 128 ( 1.3A)
THR  A  50 ( 0.8A)
TYR  A  83 ( 1.3A)
 1.24A 1rmtB-3gleA:
undetectable		 1rmtB-3gleA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE

(Streptococcus
pneumoniae) 		PF01380
(SIS) 		4 PHE A 353
TYR A 234
LEU A 284
TYR A 349
 None
 1.25A 1rmtB-3i0zA:
undetectable		 1rmtB-3i0zA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3it8 2L PROTEIN

(Tanapox virus) 		no annotation 4 PHE D 207
THR D 182
TYR D 208
LYS D 180
 None
 1.17A 1rmtB-3it8D:
undetectable		 1rmtB-3it8D:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ixw HEMOCYANIN AA6 CHAIN

(Androctonus
australis) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 PHE A 624
GLU A 211
TYR A 159
LEU A 433
 None
 1.19A 1rmtB-3ixwA:
undetectable		 1rmtB-3ixwA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		4 PHE X1082
TYR X1248
LEU X1126
THR X1243
 None
 1.03A 1rmtB-3jb9X:
undetectable		 1rmtB-3jb9X:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1m ORF904

(Sulfolobus
islandicus) 		PF09250
(Prim-Pol)
PF13010
(pRN1_helical) 		4 PHE A 353
LEU A 335
THR A 349
TYR A 352
 None
 1.19A 1rmtB-3m1mA:
undetectable		 1rmtB-3m1mA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m6j UNCHARACTERIZED
PROTEIN

(Leptospirillum
rubarum) 		no annotation 4 GLU A  52
TYR A 107
THR A  44
TYR A  67
 None
 1.15A 1rmtB-3m6jA:
undetectable		 1rmtB-3m6jA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n4x MONOPOLIN COMPLEX
SUBUNIT CSM1

(Saccharomyces
cerevisiae) 		PF12539
(Csm1) 		4 PHE A 171
TYR A 156
LEU A 157
LYS A 177
 None
 1.18A 1rmtB-3n4xA:
undetectable		 1rmtB-3n4xA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nas BETA-PHOSPHOGLUCOMUT
ASE

(Bacillus
subtilis) 		PF13419
(HAD_2) 		4 GLU A  52
LEU A  51
THR A  65
TYR A  64
 None
 1.08A 1rmtB-3nasA:
8.4		 1rmtB-3nasA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzt GLUTAMATE--CYSTEINE
LIGASE

(Francisella
tularensis) 		PF04262
(Glu_cys_ligase) 		4 GLU A 332
TYR A 405
LEU A 329
LYS A  65
 None
None
None
SO4  A 510 (-2.6A)
 1.01A 1rmtB-3nztA:
undetectable		 1rmtB-3nztA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)

(Doryteuthis
pealeii) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 PHE A 305
GLU A 282
TYR A 283
LEU A 279
 None
 1.10A 1rmtB-3qr1A:
undetectable		 1rmtB-3qr1A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rc0 N-LYSINE
METHYLTRANSFERASE
SETD6

(Homo sapiens) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		4 GLU A 301
LEU A 293
THR A 284
TYR A 285
 None
None
None
SAM  A 484 (-4.8A)
 1.24A 1rmtB-3rc0A:
undetectable		 1rmtB-3rc0A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s51 FANCONI ANEMIA GROUP
I PROTEIN HOMOLOG

(Mus musculus) 		PF14674
(FANCI_S1-cap)
PF14675
(FANCI_S1)
PF14676
(FANCI_S2)
PF14677
(FANCI_S3)
PF14678
(FANCI_S4)
PF14679
(FANCI_HD1)
PF14680
(FANCI_HD2) 		4 PHE A 958
GLU A 977
TYR A 884
LEU A 908
 None
 1.19A 1rmtB-3s51A:
undetectable		 1rmtB-3s51A:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3srz TOXIN A

(Clostridioides
difficile) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 PHE A  58
LEU A  71
THR A  25
TYR A  23
 None
 1.12A 1rmtB-3srzA:
undetectable		 1rmtB-3srzA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3syb GLYCINE-GLUTAMATE
DIPEPTIDE PORIN OPDP

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 PHE A 100
LEU A 148
THR A  94
TYR A  93
 None
None
SO4  A 468 (-4.2A)
SO4  A 469 (-4.8A)
 1.26A 1rmtB-3sybA:
undetectable		 1rmtB-3sybA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0w WN1 222-5 FAB
(IGG2A) HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 PHE H 146
LEU H 170
THR H 117
TYR H 145
 None
 1.24A 1rmtB-3v0wH:
undetectable		 1rmtB-3v0wH:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wq4 BETA-PRIMEVEROSIDASE

(Camellia
sinensis) 		PF00232
(Glyco_hydro_1) 		4 PHE A 171
GLU A 165
LEU A 160
TYR A 168
 None
 1.18A 1rmtB-3wq4A:
1.6		 1rmtB-3wq4A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ckg ARF-GAP WITH
COILED-COIL, ANK
REPEAT AND PH
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00169
(PH)
PF16746
(BAR_3) 		4 PHE A  83
GLU A 209
LEU A 213
THR A  84
 None
 1.16A 1rmtB-4ckgA:
undetectable		 1rmtB-4ckgA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4c MULTIDRUG RESISTANCE
PROTEIN PGP-1

(Caenorhabditis
elegans) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 PHE A 323
LEU A 319
THR A  27
LYS A  30
 None
None
None
0SA  A1406 ( 4.1A)
 1.18A 1rmtB-4f4cA:
undetectable		 1rmtB-4f4cA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fgw GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
[NAD(+)] 1

(Saccharomyces
cerevisiae) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		4 PHE A 227
GLU A  55
TYR A 226
THR A  48
 None
 1.25A 1rmtB-4fgwA:
2.8		 1rmtB-4fgwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grx AMINOTRANSFERASE

(Paracoccus
denitrificans) 		PF00202
(Aminotran_3) 		4 GLU A 436
TYR A  40
LEU A  50
THR A 430
 None
 1.22A 1rmtB-4grxA:
2.6		 1rmtB-4grxA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gsl AUTOPHAGY-RELATED
PROTEIN 3

(Saccharomyces
cerevisiae) 		PF03986
(Autophagy_N)
PF03987
(Autophagy_act_C)
PF10381
(Autophagy_C) 		4 PHE C  44
LEU C 291
THR C  46
LYS C  48
 None
 0.99A 1rmtB-4gslC:
undetectable		 1rmtB-4gslC:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hao PROBABLE INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE

(Yersinia pestis) 		PF01513
(NAD_kinase) 		4 PHE A 100
TYR A 277
LEU A 281
THR A 185
 None
 1.19A 1rmtB-4haoA:
3.8		 1rmtB-4haoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iel GLUTATHIONE
S-TRANSFERASE,
N-TERMINAL DOMAIN
PROTEIN

(Burkholderia
ambifaria) 		PF13417
(GST_N_3) 		4 PHE A 152
TYR A 188
LEU A 192
THR A 159
 None
 1.13A 1rmtB-4ielA:
undetectable		 1rmtB-4ielA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 PHE A 269
TYR A 275
LEU A 271
THR A 226
 None
 1.24A 1rmtB-4p4sA:
1.9		 1rmtB-4p4sA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		4 PHE B 269
TYR B 275
LEU B 271
THR B 226
 None
 1.25A 1rmtB-4p4sB:
undetectable		 1rmtB-4p4sB:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4po6 NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2

(Homo sapiens) 		no annotation 4 GLU A 159
LEU A 263
THR A 272
TYR A 108
 None
None
GOL  A 603 (-4.2A)
None
 1.26A 1rmtB-4po6A:
undetectable		 1rmtB-4po6A:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qeo HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC
SUVH4

(Arabidopsis
thaliana) 		PF00856
(SET)
PF02182
(SAD_SRA)
PF05033
(Pre-SET) 		4 PHE A 549
GLU A 492
TYR A 493
LYS A 456
 None
SAH  A 801 ( 3.2A)
SAH  A 801 (-4.0A)
SAH  A 801 (-4.7A)
 1.08A 1rmtB-4qeoA:
undetectable		 1rmtB-4qeoA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r04 TOXIN A

(Clostridioides
difficile) 		PF11713
(Peptidase_C80)
PF12918
(TcdB_N)
PF12919
(TcdA_TcdB)
PF12920
(TcdA_TcdB_pore) 		4 PHE A  58
LEU A  71
THR A  25
TYR A  23
 None
 1.20A 1rmtB-4r04A:
undetectable		 1rmtB-4r04A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3q 17 KDA LIPOPROTEIN

(Treponema
pallidum) 		PF04170
(NlpE) 		4 GLU A  96
TYR A  98
LEU A  81
THR A  39
 None
 1.15A 1rmtB-4u3qA:
undetectable		 1rmtB-4u3qA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 3
ORIGIN RECOGNITION
COMPLEX SUBUNIT 6

(Drosophila
melanogaster) 		PF07034
(ORC3_N)
no annotation 		4 PHE C 362
LEU C 379
TYR F 225
LYS F 223
 None
 1.18A 1rmtB-4xgcC:
undetectable		 1rmtB-4xgcC:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xtk CRISPR-ASSOCIATED
ENDONUCLEASE CAS1

(Thermotoga
maritima) 		PF01867
(Cas_Cas1) 		4 GLU A 276
TYR A 275
LEU A 279
THR A 195
 None
 1.10A 1rmtB-4xtkA:
undetectable		 1rmtB-4xtkA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwj CHIMERA PROTEIN OF
HUMAN RHODOPSIN,
MOUSE S-ARRESTIN,
AND T4 ENDOLYSIN

(Escherichia
virus T4;
Homo sapiens;
Mus musculus) 		PF00001
(7tm_1)
PF00339
(Arrestin_N)
PF00959
(Phage_lysozyme)
PF02752
(Arrestin_C)
PF10413
(Rhodopsin_N) 		4 PHE A  13
TYR A  30
LEU A  31
THR A   4
 None
 1.25A 1rmtB-4zwjA:
undetectable		 1rmtB-4zwjA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah1 TRIACYLGLYCEROL
LIPASE

(Clostridium
botulinum) 		no annotation 4 PHE A 329
TYR A 443
LEU A 447
THR A 226
 None
 1.09A 1rmtB-5ah1A:
undetectable		 1rmtB-5ah1A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aiw TRAH

(Enterococcus
faecalis) 		no annotation 4 PHE A  70
LEU A 101
THR A  73
TYR A  75
 None
 1.23A 1rmtB-5aiwA:
undetectable		 1rmtB-5aiwA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5azh EEEWEEL
PEPTIDE,PROTEIN
LGG-2

(Caenorhabditis
elegans;
synthetic
construct) 		PF02991
(Atg8) 		4 PHE A  89
LEU A  83
THR A 124
TYR A 123
 None
 1.24A 1rmtB-5azhA:
undetectable		 1rmtB-5azhA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdh MAJOR ACID
PHOSPHATASE

(Legionella
pneumophila) 		PF00328
(His_Phos_2) 		4 TYR A 114
LEU A 113
THR A  91
TYR A 274
 None
 1.10A 1rmtB-5cdhA:
undetectable		 1rmtB-5cdhA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czz CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Staphylococcus
aureus) 		PF13395
(HNH_4)
PF16592
(Cas9_REC) 		4 PHE A 197
LEU A  71
THR A 200
TYR A 201
 None
 1.08A 1rmtB-5czzA:
undetectable		 1rmtB-5czzA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6n PROTEIN LGG-2

(Caenorhabditis
elegans) 		PF02991
(Atg8) 		4 PHE A  89
LEU A  83
THR A 124
TYR A 123
 None
 1.13A 1rmtB-5e6nA:
undetectable		 1rmtB-5e6nA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f75 THIOCYANATE
DEHYDROGENASE

(Thioalkalivibrio
paradoxus) 		no annotation 4 PHE A 338
GLU A 228
LEU A 316
LYS A 323
 None
 1.18A 1rmtB-5f75A:
undetectable		 1rmtB-5f75A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i70 PLASMEPSIN IV

(Plasmodium
falciparum) 		no annotation 4 LEU B 301
THR B 267
TYR B 266
LYS B 265
 None
 1.23A 1rmtB-5i70B:
undetectable		 1rmtB-5i70B:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ir6 BD-TYPE QUINOL
OXIDASE SUBUNIT I
BD-TYPE QUINOL
OXIDASE SUBUNIT II

(Geobacillus
stearothermophilus) 		PF01654
(Cyt_bd_oxida_I)
PF02322
(Cyt_bd_oxida_II) 		4 PHE B  67
GLU A 101
LEU A  98
THR A  73
 None
HEB  A 502 (-3.0A)
None
HEB  A 502 (-4.6A)
 0.96A 1rmtB-5ir6B:
undetectable		 1rmtB-5ir6B:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldt MOMP PORIN

(Campylobacter
jejuni) 		PF05538
(Campylo_MOMP) 		5 PHE A 303
TYR A 276
LEU A 310
THR A 305
TYR A 304
 None
 1.41A 1rmtB-5ldtA:
undetectable		 1rmtB-5ldtA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lol GLUTATHIONE
S-TRANSFERASE DHAR2

(Arabidopsis
thaliana) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 PHE A 141
TYR A 183
LEU A 187
THR A 148
 None
 1.10A 1rmtB-5lolA:
undetectable		 1rmtB-5lolA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lp8 E3 UBIQUITIN-PROTEIN
LIGASE HUWE1

(Homo sapiens) 		no annotation 4 PHE B4128
TYR B4133
THR B4090
TYR B4127
 None
 1.22A 1rmtB-5lp8B:
undetectable		 1rmtB-5lp8B:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oex -

(-) 		no annotation 4 PHE A 338
GLU A 228
LEU A 316
LYS A 323
 None
 1.24A 1rmtB-5oexA:
undetectable		 1rmtB-5oexA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5swi SUGAR HYDROLASE

(Streptococcus
pneumoniae) 		no annotation 4 PHE B 516
LEU B 506
THR B 515
TYR B 519
 None
 1.19A 1rmtB-5swiB:
undetectable		 1rmtB-5swiB:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tir SUPEROXIDE DISMUTASE

(Trichoderma
reesei) 		no annotation 4 PHE A 205
GLU A  83
LEU A  80
LYS A 209
 None
 1.05A 1rmtB-5tirA:
undetectable		 1rmtB-5tirA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tum TETRACYCLINE
DESTRUCTASE TET(56)

(Legionella
longbeachae) 		PF01494
(FAD_binding_3) 		4 PHE A 327
LEU A 316
THR A 328
TYR A 330
 None
 1.19A 1rmtB-5tumA:
undetectable		 1rmtB-5tumA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u56 STRINGENT STARVATION
PROTEIN A

(Francisella
tularensis) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		4 PHE C 142
TYR C 179
LEU C 183
THR C 149
 None
 0.91A 1rmtB-5u56C:
undetectable		 1rmtB-5u56C:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7w APYRASE

(Trifolium
repens) 		PF01150
(GDA1_CD39) 		4 PHE A 209
TYR A 362
LEU A 366
TYR A 206
 None
 1.25A 1rmtB-5u7wA:
undetectable		 1rmtB-5u7wA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u9z PHOSPHOGLYCEROL
TRANSFERASE

(Streptococcus
pyogenes) 		no annotation 4 PHE A 558
GLU A 534
TYR A 554
THR A 539
 None
 1.23A 1rmtB-5u9zA:
undetectable		 1rmtB-5u9zA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v3n MONOPOLIN COMPLEX
SUBUNIT CSM1
ULP2P,TOPOISOMERASE
1-ASSOCIATED FACTOR
2 CHIMERA

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae x
Saccharomyces
kudriavzevii) 		PF12539
(Csm1)
no annotation 		4 PHE B  59
TYR A 156
LEU A 157
LYS A 177
 None
 1.17A 1rmtB-5v3nB:
undetectable		 1rmtB-5v3nB:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vcs ALPHA-1,6-MANNOSYL-G
LYCOPROTEIN
2-BETA-N-ACETYLGLUCO
SAMINYLTRANSFERASE

(Homo sapiens) 		no annotation 4 PHE A 338
LEU A 353
THR A 340
TYR A 341
 None
 1.09A 1rmtB-5vcsA:
1.3		 1rmtB-5vcsA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vvw UDP-N-ACETYLMURAMATE
--L-ALANINE LIGASE

(Pseudomonas
aeruginosa) 		PF01225
(Mur_ligase)
PF08245
(Mur_ligase_M) 		4 GLU A 212
LEU A 179
TYR A 199
LYS A 205
 None
 1.11A 1rmtB-5vvwA:
undetectable		 1rmtB-5vvwA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xzb CYCLIC GMP-AMP
SYNTHASE

(Mus musculus) 		PF03281
(Mab-21) 		4 GLU A 479
LEU A 480
THR A 231
LYS A 472
 None
 1.07A 1rmtB-5xzbA:
undetectable		 1rmtB-5xzbA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y09 PROTEASE DO-LIKE 9

(Arabidopsis
thaliana) 		no annotation 4 PHE A 330
TYR A 327
THR A 412
TYR A 411
 None
 1.19A 1rmtB-5y09A:
undetectable		 1rmtB-5y09A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c6l V-TYPE PROTON ATPASE
SUBUNIT A, VACUOLAR
ISOFORM

(Saccharomyces
cerevisiae) 		no annotation 4 PHE A 236
GLU A 200
LEU A 203
THR A 215
 None
 1.26A 1rmtB-6c6lA:
undetectable		 1rmtB-6c6lA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c8s LOGANIC ACID
O-METHYLTRANSFERASE

(Catharanthus
roseus) 		no annotation 4 PHE A 236
GLU A 190
TYR A 197
LYS A 195
 None
 1.18A 1rmtB-6c8sA:
undetectable		 1rmtB-6c8sA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6du8 -

(-) 		no annotation 4 GLU A 252
LEU A 253
THR A 246
TYR A 247
 None
 1.04A 1rmtB-6du8A:
undetectable		 1rmtB-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gdg NANOBODY NB35

(Lama glama) 		no annotation 4 LEU E  81
THR E  61
TYR E  60
LYS E  65
 None
 1.17A 1rmtB-6gdgE:
undetectable		 1rmtB-6gdgE:
18.84