SIMILAR PATTERNS OF AMINO ACIDS FOR 1RJD_B_SAMB802_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dnp | DNA PHOTOLYASE (Escherichiacoli) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7) | 5 | GLN A 369GLY A 362SER A 368LEU A 313LEU A 351 | None | 1.03A | 1rjdB-1dnpA:undetectable | 1rjdB-1dnpA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8f | BENZYL ALCOHOLDEHYDROGENASE (Acinetobactercalcoaceticus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ILE A 218ALA A 181GLY A 203LEU A 234LEU A 208 | None | 0.99A | 1rjdB-1f8fA:3.6 | 1rjdB-1f8fA:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fcd | FLAVOCYTOCHROME CSULFIDEDEHYDROGENASE(FLAVIN-BINDINGSUBUNIT) (Allochromatiumvinosum) |
PF07992(Pyr_redox_2)PF09242(FCSD-flav_bind) | 5 | ILE A 187ALA A 156GLY A 222SER A 225TYR A 166 | None | 1.05A | 1rjdB-1fcdA:undetectable | 1rjdB-1fcdA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nbw | GLYCEROL DEHYDRATASEREACTIVASE ALPHASUBUNIT (Klebsiellapneumoniae) |
PF08841(DDR) | 5 | ILE A 341THR A 86ALA A 263GLY A 360LEU A 447 | None | 1.09A | 1rjdB-1nbwA:undetectable | 1rjdB-1nbwA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o3t | CATABOLITE GENEACTIVATOR PROTEIN (Escherichiacoli) |
PF00027(cNMP_binding)PF00325(Crp) | 5 | ILE A 70GLY A 74LEU A 116LEU A 39TYR A 40 | CMP A 762 (-4.9A)CMP A 762 ( 4.9A)NoneNoneNone | 1.02A | 1rjdB-1o3tA:undetectable | 1rjdB-1o3tA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p0c | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Pelophylaxperezi) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A1153GLY A1121GLY A1142SER A1144LEU A1122 | None | 1.06A | 1rjdB-1p0cA:3.8 | 1rjdB-1p0cA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qor | QUINONEOXIDOREDUCTASE (Escherichiacoli) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ILE A 101ALA A 119GLY A 62SER A 96LEU A 92 | None | 1.07A | 1rjdB-1qorA:4.9 | 1rjdB-1qorA:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qrz | PLASMINOGEN (Homo sapiens) |
PF00089(Trypsin) | 5 | ILE A 682THR A 759ALA A 601GLY A 590LEU A 697 | None | 1.08A | 1rjdB-1qrzA:undetectable | 1rjdB-1qrzA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r8w | GLYCEROL DEHYDRATASE (Clostridiumbutyricum) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | ILE A 48GLY A 533GLY A 540SER A 523LEU A 205 | None | 0.96A | 1rjdB-1r8wA:undetectable | 1rjdB-1r8wA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rrm | LACTALDEHYDEREDUCTASE (Escherichiacoli) |
PF00465(Fe-ADH) | 5 | THR A 103ASP A 102GLY A 96GLY A 98LEU A 42 | NoneAPR A 389 ( 4.5A)NoneAPR A 389 (-3.2A)APR A 389 (-4.9A) | 1.05A | 1rjdB-1rrmA:2.1 | 1rjdB-1rrmA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vft | ALANINE RACEMASE (Streptomyceslavendulae) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 6 | ASP A 13ALA A 249GLY A 378LEU A 379CYH A 49TYR A 375 | None | 1.46A | 1rjdB-1vftA:undetectable | 1rjdB-1vftA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xtz | RIBOSE-5-PHOSPHATEISOMERASE (Saccharomycescerevisiae) |
PF06026(Rib_5-P_isom_A) | 5 | ASP A 110ALA A 109GLY A 235GLY A 121LEU A 236 | None | 1.07A | 1rjdB-1xtzA:undetectable | 1rjdB-1xtzA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yif | BETA-1,4-XYLOSIDASE (Bacillussubtilis) |
PF04616(Glyco_hydro_43) | 5 | GLN A 244THR A 265GLY A 309SER A 235LEU A 311 | None | 1.10A | 1rjdB-1yifA:undetectable | 1rjdB-1yifA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yrz | XYLANBETA-1,4-XYLOSIDASE (Bacillushalodurans) |
PF04616(Glyco_hydro_43) | 6 | ILE A1284GLN A1285THR A1282GLY A1251GLY A1249LEU A1253 | None | 1.17A | 1rjdB-1yrzA:undetectable | 1rjdB-1yrzA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zzw | DUAL SPECIFICITYPROTEIN PHOSPHATASE10 (Homo sapiens) |
PF00782(DSPc) | 5 | ILE A 325GLY A 332GLY A 411LEU A 405LEU A 322 | NoneNoneSO4 A 501 (-4.2A)NoneNone | 1.04A | 1rjdB-1zzwA:undetectable | 1rjdB-1zzwA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b0t | NADP ISOCITRATEDEHYDROGENASE (Corynebacteriumglutamicum) |
PF03971(IDH) | 5 | GLN A 590THR A 706ASP A 707LEU A 14LEU A 719 | None | 1.08A | 1rjdB-2b0tA:undetectable | 1rjdB-2b0tA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dch | PUTATIVE HOMINGENDONUCLEASE (Thermoproteus) |
PF14528(LAGLIDADG_3) | 5 | ILE X 25GLN X 27GLY X 101LEU X 39LEU X 7 | None | 1.10A | 1rjdB-2dchX:undetectable | 1rjdB-2dchX:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eh6 | ACETYLORNITHINEAMINOTRANSFERASE (Aquifexaeolicus) |
PF00202(Aminotran_3) | 5 | ASP A 212ALA A 238GLY A 129SER A 126LEU A 135 | PLP A1001 (-2.9A)NonePLP A1001 ( 4.2A)NoneNone | 1.07A | 1rjdB-2eh6A:2.6 | 1rjdB-2eh6A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fzw | ALCOHOLDEHYDROGENASE CLASSIII CHI CHAIN (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 152GLY A 120GLY A 141SER A 143LEU A 121 | None | 0.99A | 1rjdB-2fzwA:2.9 | 1rjdB-2fzwA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gr8 | ADHESIN (Haemophilusinfluenzae) |
PF03895(YadA_anchor) | 5 | GLN A1058THR A1028ALA A1031GLY A1060SER A1084 | None | 1.06A | 1rjdB-2gr8A:undetectable | 1rjdB-2gr8A:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hey | TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER 4 (Mus musculus) |
no annotation | 5 | ILE F 168GLY F 65SER F 78LEU F 154LEU F 106 | None | 1.09A | 1rjdB-2heyF:undetectable | 1rjdB-2heyF:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i3o | GAMMA-GLUTAMYLTRANSFERASE RELATEDPROTEIN (Thermoplasmaacidophilum) |
PF01019(G_glu_transpept) | 5 | ILE A 347GLN A 348GLY A 77GLY A 111LEU A 75 | None | 1.09A | 1rjdB-2i3oA:undetectable | 1rjdB-2i3oA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kzt | PROGRAMMED CELLDEATH PROTEIN 4 (Homo sapiens) |
PF02847(MA3) | 5 | ILE A 273THR A 233ASP A 235SER A 239LEU A 222 | None | 0.99A | 1rjdB-2kztA:undetectable | 1rjdB-2kztA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nrr | UVRABC SYSTEMPROTEIN C (Thermotogamaritima) |
PF08459(UvrC_HhH_N) | 5 | ILE A 483GLN A 482THR A 487LEU A 477LEU A 454 | None | 0.97A | 1rjdB-2nrrA:undetectable | 1rjdB-2nrrA:20.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ob1 | LEUCINE CARBOXYLMETHYLTRANSFERASE 1 (Saccharomycescerevisiae) |
PF04072(LCM) | 7 | ALA A 12GLY A 105GLY A 107LEU A 176CYH A 202LEU A 203TYR A 206 | None | 0.26A | 1rjdB-2ob1A:53.0 | 1rjdB-2ob1A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ob1 | LEUCINE CARBOXYLMETHYLTRANSFERASE 1 (Saccharomycescerevisiae) |
PF04072(LCM) | 7 | ALA A 12GLY A 105SER A 132LEU A 176CYH A 202LEU A 203TYR A 206 | None | 0.66A | 1rjdB-2ob1A:53.0 | 1rjdB-2ob1A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oud | DUAL SPECIFICITYPROTEIN PHOSPHATASE10 (Homo sapiens) |
PF00782(DSPc) | 5 | ILE A 325GLY A 332GLY A 411LEU A 405LEU A 322 | None | 1.01A | 1rjdB-2oudA:undetectable | 1rjdB-2oudA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pa6 | ENOLASE (Methanocaldococcusjannaschii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ILE A 173ALA A 395GLY A 215LEU A 229LEU A 195 | None | 1.00A | 1rjdB-2pa6A:undetectable | 1rjdB-2pa6A:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pke | HALOACIDDELAHOGENASE-LIKEFAMILY HYDROLASE (Xanthomonascampestris) |
PF13419(HAD_2) | 5 | ILE A 184THR A 205GLY A 19LEU A 131LEU A 23 | None | 0.89A | 1rjdB-2pkeA:2.7 | 1rjdB-2pkeA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uyo | HYPOTHETICAL PROTEINML2640 (Mycobacteriumleprae) |
PF04072(LCM) | 5 | THR A 17GLY A 112LEU A 162LEU A 188TYR A 191 | None | 0.78A | 1rjdB-2uyoA:23.3 | 1rjdB-2uyoA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) |
PF00310(GATase_2)PF01493(GXGXG)PF01645(Glu_synthase)PF04898(Glu_syn_central) | 5 | GLN A 187ALA A 33GLY A 43GLY A 41CYH A 1 | NoneNoneNoneNoneOMT A2473 (-3.8A) | 1.07A | 1rjdB-2vdcA:undetectable | 1rjdB-2vdcA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y05 | PROSTAGLANDINREDUCTASE 1 (Homo sapiens) |
PF00107(ADH_zinc_N)PF16884(ADH_N_2) | 5 | ALA A 153GLY A 123GLY A 120LEU A 284LEU A 127 | NAP A 701 (-3.3A)NoneNoneNoneEDO A1332 (-3.9A) | 1.07A | 1rjdB-2y05A:5.8 | 1rjdB-2y05A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zwa | LEUCINE CARBOXYLMETHYLTRANSFERASE 2 (Saccharomycescerevisiae) |
PF04072(LCM)PF13418(Kelch_4) | 7 | ILE A 27GLN A 28THR A 30GLY A 115GLY A 117LEU A 197TYR A 229 | SAH A 801 (-4.4A)NoneSAH A 801 (-4.5A)SAH A 801 (-3.5A)SAH A 801 (-3.4A)SAH A 801 (-3.7A)None | 0.42A | 1rjdB-2zwaA:31.4 | 1rjdB-2zwaA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ce9 | GLYCEROLDEHYDROGENASE (Clostridiumacetobutylicum) |
PF13685(Fe-ADH_2) | 5 | THR A 146ALA A 144GLY A 125SER A 116LEU A 229 | None | 1.05A | 1rjdB-3ce9A:undetectable | 1rjdB-3ce9A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eh2 | PROTEIN TRANSPORTPROTEIN SEC24C (Homo sapiens) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 5 | THR A 487ASP A 423ALA A 424GLY A 310GLY A 364 | None | 1.09A | 1rjdB-3eh2A:undetectable | 1rjdB-3eh2A:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3guw | UNCHARACTERIZEDPROTEIN AF_1765 (Archaeoglobusfulgidus) |
PF01026(TatD_DNase) | 5 | THR A 130ASP A 159GLY A 177LEU A 170LEU A 166 | None | 1.10A | 1rjdB-3guwA:undetectable | 1rjdB-3guwA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic9 | DIHYDROLIPOAMIDEDEHYDROGENASE (Colwelliapsychrerythraea) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | GLN A 388ALA A 422GLY A 399SER A 391LEU A 400 | None | 1.01A | 1rjdB-3ic9A:undetectable | 1rjdB-3ic9A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ifr | CARBOHYDRATE KINASE,FGGY (Rhodospirillumrubrum) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | ILE A 419ALA A 406GLY A 410SER A 413LEU A 379 | None | 1.07A | 1rjdB-3ifrA:undetectable | 1rjdB-3ifrA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j1e | CHAPERONIN BETASUBUNIT (Acidianustengchongensis) |
PF00118(Cpn60_TCP1) | 5 | ILE A 383THR A 220ASP A 219GLY A 386GLY A 215 | None | 1.04A | 1rjdB-3j1eA:undetectable | 1rjdB-3j1eA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kif | 5-BLADEDBETA-PROPELLERLECTIN (syntheticconstruct) |
PF14517(Tachylectin) | 5 | GLN A 30ASP A 46GLY A 72LEU A 48TYR A 49 | None | 1.02A | 1rjdB-3kifA:undetectable | 1rjdB-3kifA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ky7 | TRNA(GUANINE-N(1)-)-METHYLTRANSFERASE (Staphylococcusaureus) |
PF01746(tRNA_m1G_MT) | 5 | ILE A 33THR A 147ASP A 148ALA A 149SER A 20 | None | 1.11A | 1rjdB-3ky7A:undetectable | 1rjdB-3ky7A:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6c | SERINE RACEMASE (Rattusnorvegicus) |
PF00291(PALP) | 5 | ILE A 57THR A 52ALA A 117GLY A 85LEU A 91 | NoneNoneNoneMLI A 341 ( 4.9A)None | 1.07A | 1rjdB-3l6cA:undetectable | 1rjdB-3l6cA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ldo | 78 KDAGLUCOSE-REGULATEDPROTEIN (Homo sapiens) |
PF00012(HSP70) | 5 | ILE A 371GLY A 254GLY A 227LEU A 334LEU A 253 | NoneNoneANP A 408 (-3.4A)NoneNone | 1.10A | 1rjdB-3ldoA:undetectable | 1rjdB-3ldoA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o7w | LEUCINE CARBOXYLMETHYLTRANSFERASE 1 (Homo sapiens) |
PF04072(LCM) | 5 | ALA A 33GLY A 98GLY A 100CYH A 199TYR A 203 | SAM A 801 (-3.6A)SAM A 801 (-3.5A)SAM A 801 ( 3.7A)SAM A 801 (-4.9A)SAM A 801 (-4.6A) | 0.54A | 1rjdB-3o7wA:30.3 | 1rjdB-3o7wA:29.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o7w | LEUCINE CARBOXYLMETHYLTRANSFERASE 1 (Homo sapiens) |
PF04072(LCM) | 5 | ALA A 33GLY A 98GLY A 100LEU A 172CYH A 199 | SAM A 801 (-3.6A)SAM A 801 (-3.5A)SAM A 801 ( 3.7A)SAM A 801 (-3.7A)SAM A 801 (-4.9A) | 0.51A | 1rjdB-3o7wA:30.3 | 1rjdB-3o7wA:29.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oxn | PUTATIVETRANSCRIPTIONALREGULATOR, LYSRFAMILY (Vibrioparahaemolyticus) |
PF03466(LysR_substrate) | 5 | ILE A 170THR A 123ALA A 219LEU A 319TYR A 291 | None | 0.99A | 1rjdB-3oxnA:undetectable | 1rjdB-3oxnA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfe | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Legionellapneumophila) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ILE A 29ASP A 98ALA A 160GLY A 131LEU A 23 | None | 1.07A | 1rjdB-3pfeA:undetectable | 1rjdB-3pfeA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qn3 | ENOLASE (Campylobacterjejuni) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ILE A 166ALA A 388GLY A 206LEU A 220LEU A 188 | None | 1.01A | 1rjdB-3qn3A:undetectable | 1rjdB-3qn3A:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqz | PUTATIVEUNCHARACTERIZEDPROTEIN YJIK (Escherichiacoli) |
PF06977(SdiA-regulated) | 5 | ILE A 143ALA A 195GLY A 296GLY A 245LEU A 100 | NoneNoneNone CA A 327 ( 4.9A)None | 0.99A | 1rjdB-3qqzA:undetectable | 1rjdB-3qqzA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t9w | SMALL LACCASE,MULTI-COPPER OXIDASE (Amycolatopsissp. ATCC 39116) |
PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 5 | ILE A 188ASP A 185GLY A 213GLY A 215LEU A 251 | None | 0.87A | 1rjdB-3t9wA:undetectable | 1rjdB-3t9wA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u5z | DNA POLYMERASEACCESSORY PROTEIN 44 (Escherichiavirus T4) |
PF00004(AAA) | 5 | THR B 207ASP B 203GLY B 55GLY B 53LEU B 25 | NoneNone08T B 700 (-3.1A)08T B 700 (-3.0A)None | 1.09A | 1rjdB-3u5zB:2.9 | 1rjdB-3u5zB:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uca | GERANYLTRANSTRANSFERASE (Clostridiumperfringens) |
PF00348(polyprenyl_synt) | 5 | ILE A 54ALA A 194GLY A 221GLY A 189LEU A 220 | None | 0.98A | 1rjdB-3ucaA:undetectable | 1rjdB-3ucaA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3va1 | MEDIATOR OF DNADAMAGE CHECKPOINTPROTEIN 1 (Mus musculus) |
PF00498(FHA) | 5 | ILE A 100ASP A 91ALA A 76GLY A 97LEU A 122 | None | 0.98A | 1rjdB-3va1A:undetectable | 1rjdB-3va1A:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1n | CARBON MONOXIDEDEHYDROGENASECORRINOID/IRON-SULFUR PROTEIN, GAMMASUBUNIT (Carboxydothermushydrogenoformans) |
PF03599(CdhD)PF04060(FeS) | 5 | ILE A 159ALA A 146GLY A 162GLY A 135LEU A 167 | None | 1.07A | 1rjdB-4c1nA:undetectable | 1rjdB-4c1nA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dn7 | ABC TRANSPORTER,ATP-BINDING PROTEIN (Methanosarcinamazei) |
PF01458(UPF0051) | 5 | ILE A 265THR A 403GLY A 374LEU A 322LEU A 324 | NoneNoneNone1PE A 501 (-4.7A)None | 0.99A | 1rjdB-4dn7A:undetectable | 1rjdB-4dn7A:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gmk | RIBOSE-5-PHOSPHATEISOMERASE A (Lactobacillussalivarius) |
PF06026(Rib_5-P_isom_A) | 5 | ASP A 87ALA A 86GLY A 204GLY A 98LEU A 205 | PO4 A 301 (-2.6A)NoneNonePO4 A 301 (-4.0A)None | 1.04A | 1rjdB-4gmkA:2.7 | 1rjdB-4gmkA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hac | MEVALONATE KINASE (Methanosarcinamazei) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | ILE A 10THR A 257ALA A 259GLY A 93GLY A 89 | None | 1.07A | 1rjdB-4hacA:undetectable | 1rjdB-4hacA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hds | ARSB (Sporomusa ovata) |
PF02277(DBI_PRT) | 5 | ILE B 167ALA B 98GLY B 170GLY B 304LEU B 232 | None | 1.01A | 1rjdB-4hdsB:undetectable | 1rjdB-4hdsB:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hea | NADH-QUINONEOXIDOREDUCTASESUBUNIT 13 (Thermusthermophilus) |
PF00361(Proton_antipo_M) | 5 | ILE M 360ALA M 317GLY M 370GLY M 444LEU M 368 | None | 1.06A | 1rjdB-4heaM:undetectable | 1rjdB-4heaM:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j72 | PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE (Aquifexaeolicus) |
PF00953(Glycos_transf_4)PF10555(MraY_sig1) | 5 | ILE A 271ASP A 265GLY A 111GLY A 114LEU A 82 | None MG A 403 (-2.7A)NoneNoneNone | 1.10A | 1rjdB-4j72A:undetectable | 1rjdB-4j72A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jgb | PUTATIVE EXPORTEDPROTEIN (Burkholderiapseudomallei) |
PF13460(NAD_binding_10) | 5 | THR A 206ALA A 204GLY A 105GLY A 103LEU A 115 | None | 1.01A | 1rjdB-4jgbA:3.7 | 1rjdB-4jgbA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ki9 | DUAL SPECIFICITYPROTEIN PHOSPHATASE12 (Homo sapiens) |
PF00782(DSPc) | 5 | ILE A 125ALA A 152GLY A 37GLY A 118LEU A 112 | NoneNoneNonePO4 A 201 (-3.8A)None | 1.09A | 1rjdB-4ki9A:undetectable | 1rjdB-4ki9A:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kpg | MEMBRANE-ANCHOREDMYCOSIN MYCP1 (Mycolicibacteriumsmegmatis) |
PF00082(Peptidase_S8) | 5 | ILE A 363THR A 366ASP A 384LEU A 346LEU A 389 | None | 1.08A | 1rjdB-4kpgA:2.2 | 1rjdB-4kpgA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n5i | ESTERASE/LIPASE (Lactobacillusrhamnosus) |
PF07859(Abhydrolase_3) | 5 | THR X 143GLY X 74GLY X 148LEU X 84TYR X 88 | None2HD X 401 (-3.9A)NoneNoneNone | 1.11A | 1rjdB-4n5iX:2.6 | 1rjdB-4n5iX:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nml | RIBULOSE 5-PHOSPHATEISOMERASE (Toxoplasmagondii) |
PF06026(Rib_5-P_isom_A) | 5 | ILE A 135ASP A 91ALA A 90GLY A 233GLY A 103 | NoneMLT A 303 (-4.5A)NoneNone CL A 301 (-3.5A) | 1.02A | 1rjdB-4nmlA:undetectable | 1rjdB-4nmlA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p6y | AMINOPEPTIDASE (Thermotogamaritima) |
PF05343(Peptidase_M42) | 5 | ILE A 95ASP A 130GLY A 106LEU A 91LEU A 127 | None | 1.06A | 1rjdB-4p6yA:undetectable | 1rjdB-4p6yA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4re2 | BETA-MANNOSIDASE/BETA-GLUCOSIDASE (Oryza sativa) |
PF00232(Glyco_hydro_1) | 5 | ILE A 219GLY A 242SER A 309LEU A 275LEU A 245 | None | 1.01A | 1rjdB-4re2A:2.1 | 1rjdB-4re2A:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w7s | PRE-MRNA-SPLICINGATP-DEPENDENT RNAHELICASE PRP28 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | ILE A 270GLN A 269GLY A 226GLY A 224LEU A 229 | None | 1.11A | 1rjdB-4w7sA:5.0 | 1rjdB-4w7sA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8f | RIBOKINASE (Vibrio cholerae) |
PF00294(PfkB) | 5 | ILE A 218ALA A 279GLY A 225GLY A 239LEU A 221 | None | 1.06A | 1rjdB-4x8fA:2.7 | 1rjdB-4x8fA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xcg | THERMOSOME SUBUNITBETA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 5 | ILE B 385THR B 222ASP B 221GLY B 388GLY B 217 | None | 0.94A | 1rjdB-4xcgB:undetectable | 1rjdB-4xcgB:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzg | PROTEIN PHOSPHATASE2C 57 (Arabidopsisthaliana) |
PF00481(PP2C) | 5 | ILE A 178ASP A 93GLY A 160GLY A 94LEU A 145 | None MN A 402 ( 2.6A)None MN A 401 (-4.2A)None | 1.08A | 1rjdB-4yzgA:undetectable | 1rjdB-4yzgA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a22 | VESICULAR STOMATITISVIRUS L POLYMERASE (Vesicularstomatitisvirus) |
PF00946(Mononeg_RNA_pol)PF14314(Methyltrans_Mon)PF14318(Mononeg_mRNAcap) | 5 | ASP A 772ALA A 301GLY A 784GLY A 589LEU A 584 | None | 1.06A | 1rjdB-5a22A:8.4 | 1rjdB-5a22A:9.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e84 | 78 KDAGLUCOSE-REGULATEDPROTEIN (Homo sapiens) |
PF00012(HSP70) | 5 | ILE A 371GLY A 254GLY A 227LEU A 334LEU A 253 | NoneNoneATP A 801 (-3.8A)NoneNone | 1.07A | 1rjdB-5e84A:undetectable | 1rjdB-5e84A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5es2 | UNCHARACTERIZEDPROTEIN LPG0634 (Legionellapneumophila) |
PF16848(SoDot-IcmSS) | 5 | ILE A 298THR A 301GLY A 282SER A 308TYR A 288 | NoneSO4 A 507 (-3.3A)NoneNoneNone | 1.07A | 1rjdB-5es2A:undetectable | 1rjdB-5es2A:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fbz | ENZYME SUBTILASESUBHAL FROM BACILLUSHALMAPALUS (Bacillushalmapalus) |
PF00082(Peptidase_S8)PF04151(PPC) | 5 | ALA A 86GLY A 78SER A 228LEU A 33LEU A 91 | NoneNone5VV A 1 ( 3.0A)NoneNone | 1.10A | 1rjdB-5fbzA:2.2 | 1rjdB-5fbzA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h36 | UNCHARACTERIZEDPROTEIN TRIC (Rhodobactersphaeroides) |
no annotation | 5 | ILE E 16GLY E 21GLY E 39LEU E 92LEU E 23 | None | 1.06A | 1rjdB-5h36E:undetectable | 1rjdB-5h36E:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hn4 | HOMOISOCITRATEDEHYDROGENASE (Thermococcuskodakarensis) |
PF00180(Iso_dh) | 5 | ILE A 82ALA A 267GLY A 9GLY A 13SER A 252 | None | 1.05A | 1rjdB-5hn4A:undetectable | 1rjdB-5hn4A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikl | GERANYL-COACARBOXYLASE,BETA-SUBUNIT (Pseudomonasaeruginosa) |
PF01039(Carboxyl_trans) | 5 | ILE B 172GLN B 169LEU B 130CYH B 105LEU B 106 | None | 1.06A | 1rjdB-5iklB:undetectable | 1rjdB-5iklB:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jay | 8-AMINO-7-OXONONANOATE SYNTHASE (Paraburkholderiaxenovorans) |
PF00155(Aminotran_1_2) | 5 | ILE A 340THR A 343ALA A 347LEU A 312LEU A 386 | None | 1.10A | 1rjdB-5jayA:undetectable | 1rjdB-5jayA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjc | CYSTEINE SYNTHASE (Brucellaabortus) |
PF00291(PALP) | 5 | GLN A 157THR A 162ALA A 164GLY A 186GLY A 190 | NoneNoneNoneLLP A 42 ( 3.7A)None | 1.10A | 1rjdB-5jjcA:undetectable | 1rjdB-5jjcA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxu | DYP-TYPE PEROXIDASEFAMILY (Thermomonosporacurvata) |
PF04261(Dyp_perox) | 5 | ILE A 167THR A 182ALA A 186GLY A 72LEU A 164 | None | 1.02A | 1rjdB-5jxuA:undetectable | 1rjdB-5jxuA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jyg | ACTIN-LIKE ATPASE (Magnetospirillummagneticum) |
PF06723(MreB_Mbl) | 5 | ILE A 261THR A 167ASP A 161GLY A 290GLY A 288 | NoneNone MG A 401 (-3.8A)NoneADP A 402 ( 4.2A) | 0.99A | 1rjdB-5jygA:undetectable | 1rjdB-5jygA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kt0 | 4-HYDROXY-TETRAHYDRODIPICOLINATEREDUCTASE (Trichormusvariabilis) |
PF01113(DapB_N)PF05173(DapB_C) | 5 | GLN A 61GLY A 83GLY A 87LEU A 67LEU A 92 | None | 1.10A | 1rjdB-5kt0A:3.9 | 1rjdB-5kt0A:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m32 | PROTEASOME SUBUNITBETA TYPE-2 (Homo sapiens) |
PF00227(Proteasome) | 5 | ILE J 183ALA J 156GLY J 6LEU J 103LEU J 115 | None | 1.10A | 1rjdB-5m32J:undetectable | 1rjdB-5m32J:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mdh | MALATE DEHYDROGENASE (Sus scrofa) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | GLN A 33GLY A 24GLY A 26LEU A 37LEU A 64 | None | 0.96A | 1rjdB-5mdhA:4.4 | 1rjdB-5mdhA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mm7 | - (-) |
no annotation | 5 | ILE K 234THR K 232ALA K 290GLY K 304LEU K 244 | None | 0.98A | 1rjdB-5mm7K:undetectable | 1rjdB-5mm7K:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 5 | ALA B 99GLY B 150GLY B 148SER B 190LEU B 137 | G2P B 501 ( 4.6A)NoneNoneNoneNone | 1.02A | 1rjdB-5n5nB:undetectable | 1rjdB-5n5nB:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n9y | ZINC TRANSPORTPROTEIN ZNTB (Escherichiacoli) |
no annotation | 5 | ILE A 230THR A 155GLY A 235GLY A 237TYR A 208 | None | 0.98A | 1rjdB-5n9yA:undetectable | 1rjdB-5n9yA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5na2 | CAPSID PROTEIN (P24) (Felineimmunodeficiencyvirus) |
no annotation | 5 | ILE A 135ASP A 64GLY A 32GLY A 29SER A 180 | None | 1.08A | 1rjdB-5na2A:undetectable | 1rjdB-5na2A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5np9 | TRNATHREONYLCARBAMOYLADENOSINE BIOSYNTHESISPROTEIN TSAE (Bacillussubtilis) |
no annotation | 5 | ILE A 17THR A 21ALA A 25GLY A 47GLY A 51 | None | 1.07A | 1rjdB-5np9A:undetectable | 1rjdB-5np9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5och | - (-) |
no annotation | 5 | GLN B 379ALA B 385GLY B 307SER B 429LEU B 311 | NoneNoneY01 B1003 ( 4.3A)Y01 B1003 ( 3.8A)None | 1.05A | 1rjdB-5ochB:2.4 | 1rjdB-5ochB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t8v | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF12765(Cohesin_HEAT)PF12830(Nipped-B_C) | 5 | GLN A 489ASP A 496GLY A 493LEU A 557LEU A 570 | None | 1.08A | 1rjdB-5t8vA:undetectable | 1rjdB-5t8vA:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tc3 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Eremotheciumgossypii) |
PF00478(IMPDH)PF00571(CBS) | 5 | ILE A 202GLN A 201THR A 206LEU A 196LEU A 224 | NoneNoneNoneGDP A 603 ( 4.6A)GDP A 603 ( 4.3A) | 1.04A | 1rjdB-5tc3A:undetectable | 1rjdB-5tc3A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tpw | GLUTAMATE RECEPTORIONOTROPIC, NMDA 2A (Rattusnorvegicus) |
PF01094(ANF_receptor) | 6 | ILE B 116THR B 120ALA B 316GLY B 97LEU B 39LEU B 89 | None | 1.33A | 1rjdB-5tpwB:undetectable | 1rjdB-5tpwB:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9p | GLUCONATE5-DEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 5 | ILE A 39GLY A 21GLY A 19LEU A 52LEU A 26 | NoneNAP A 301 ( 4.2A)NAP A 301 (-3.7A)NoneNone | 1.06A | 1rjdB-5u9pA:5.8 | 1rjdB-5u9pA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxu | RIBOSOMAL PROTEINUS5 (Toxoplasmagondii) |
PF00333(Ribosomal_S5)PF03719(Ribosomal_S5_C) | 5 | ILE C 137ASP C 87GLY C 113LEU C 144LEU C 84 | None | 1.07A | 1rjdB-5xxuC:undetectable | 1rjdB-5xxuC:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z9s | GLYCOSYL HYDROLASEFAMILY 3 PROTEIN (Bifidobacteriumlongum) |
no annotation | 5 | GLN A 565THR A 155ALA A 152SER A 561LEU A 389 | None | 1.10A | 1rjdB-5z9sA:undetectable | 1rjdB-5z9sA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT B (Pyrococcusfuriosus) |
no annotation | 5 | ILE F 27GLN F 40THR F 44ALA F 46GLY F 126 | None | 1.10A | 1rjdB-6cfwF:undetectable | 1rjdB-6cfwF:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6e2q | - (-) |
no annotation | 5 | ILE A 289THR A 267GLY A 294GLY A 292LEU A 316 | None | 0.92A | 1rjdB-6e2qA:undetectable | 1rjdB-6e2qA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eoe | 78 KDAGLUCOSE-REGULATEDPROTEIN (Cricetulusgriseus) |
no annotation | 5 | ILE A 371GLY A 254GLY A 227LEU A 334LEU A 253 | NoneNoneADP A 603 ( 2.9A)NoneNone | 1.10A | 1rjdB-6eoeA:undetectable | 1rjdB-6eoeA:19.78 |