SIMILAR PATTERNS OF AMINO ACIDS FOR 1RI4_A_SAMA299
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dkp | PHYTASE (Escherichiacoli) |
PF00328(His_Phos_2) | 5 | GLY A 59GLY A 103ILE A 55ALA A 99GLN A 64 | None | 1.04A | 1ri4A-1dkpA:undetectable | 1ri4A-1dkpA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gtm | GLUTAMATEDEHYDROGENASE (Pyrococcusfuriosus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | GLY A 224ILE A 230ALA A 191ASP A 234SER A 232 | SO4 A 421 ( 4.9A)NoneNoneNoneNone | 1.08A | 1ri4A-1gtmA:4.0 | 1ri4A-1gtmA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1idm | 3-ISOPROPYLMALATEDEHYDROGENASE (Thermusthermophilus) |
PF00180(Iso_dh) | 5 | GLY A 10GLY A 12ILE A 277ALA A 283ASP A 276 | None | 1.21A | 1ri4A-1idmA:undetectable | 1ri4A-1idmA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1im4 | DBH (Sulfolobussolfataricus) |
PF00817(IMS)PF11798(IMS_HHH) | 5 | GLY A 165GLY A 144ILE A 167ALA A 146SER A 159 | None | 1.15A | 1ri4A-1im4A:undetectable | 1ri4A-1im4A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqb | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Clostridiumbeijerinckii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A1158GLY A1182ILE A1164ALA A1186SER A1263 | None | 1.05A | 1ri4A-1jqbA:6.9 | 1ri4A-1jqbA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qwr | MANNOSE-6-PHOSPHATEISOMERASE (Bacillussubtilis) |
PF01238(PMI_typeI) | 5 | GLY A 19ILE A 16ASP A 201SER A 202PHE A 12 | None | 0.95A | 1ri4A-1qwrA:undetectable | 1ri4A-1qwrA:22.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ri3 | MRNA CAPPING ENZYME (Encephalitozooncuniculi) |
PF03291(Pox_MCEL) | 5 | GLY A 92ALA A 120ASP A 122SER A 123TYR A 124 | NoneNoneSAH A 299 (-3.2A)SAH A 299 (-3.1A)SAH A 299 (-4.0A) | 1.19A | 1ri4A-1ri3A:43.3 | 1ri4A-1ri3A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ri3 | MRNA CAPPING ENZYME (Encephalitozooncuniculi) |
PF03291(Pox_MCEL) | 12 | LYS A 54GLY A 72GLY A 74ILE A 95ALA A 96ASP A 122SER A 123TYR A 124GLN A 140PHE A 141SER A 142TYR A 145 | SAH A 299 (-3.0A)SAH A 299 (-3.3A)SAH A 299 (-3.5A)SAH A 299 (-3.8A)SAH A 299 ( 3.8A)SAH A 299 (-3.2A)SAH A 299 (-3.1A)SAH A 299 (-4.0A)NoneNoneSAH A 299 (-3.0A)SAH A 299 (-4.2A) | 0.41A | 1ri4A-1ri3A:43.3 | 1ri4A-1ri3A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u60 | PROBABLE GLUTAMINASEYBAS (Escherichiacoli) |
PF04960(Glutaminase) | 5 | GLY A 261GLY A 263ALA A 27TYR A 244SER A 66 | None | 0.94A | 1ri4A-1u60A:undetectable | 1ri4A-1u60A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uar | RHODANESE (Thermusthermophilus) |
PF00581(Rhodanese) | 5 | GLY A 178GLY A 283ILE A 280ALA A 281GLN A 174 | None | 1.03A | 1ri4A-1uarA:undetectable | 1ri4A-1uarA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ulv | GLUCODEXTRANASE (Arthrobacterglobiformis) |
PF00723(Glyco_hydro_15)PF09136(Glucodextran_B)PF09137(Glucodextran_N)PF09985(Glucodextran_C) | 5 | GLY A 10GLY A 7ILE A 212ALA A 207ASP A 146 | NoneNoneNoneNone CA A2001 (-3.0A) | 0.91A | 1ri4A-1ulvA:undetectable | 1ri4A-1ulvA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vdw | HYPOTHETICAL PROTEINPH1897 (Pyrococcushorikoshii) |
PF00459(Inositol_P) | 5 | GLY A 88ILE A 175ALA A 176ASP A 192TYR A 196 | NoneEDO A1002 (-4.0A)NoneNoneNone | 1.13A | 1ri4A-1vdwA:undetectable | 1ri4A-1vdwA:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zun | SULFATE ADENYLATETRANSFERASE, SUBUNIT1/ADENYLYLSULFATEKINASE (Pseudomonassyringae groupgenomosp. 3) |
PF00009(GTP_EFTU) | 5 | GLY B 406GLY B 414ILE B 433ALA B 337SER B 408 | None | 1.15A | 1ri4A-1zunB:2.9 | 1ri4A-1zunB:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cn3 | BETA-1,4-XYLOGLUCANHYDROLASE (Ruminiclostridiumthermocellum) |
PF02012(BNR) | 5 | GLY A 119GLY A 152ALA A 70SER A 97TYR A 96 | NoneNoneGLC A1769 (-3.5A)NoneXYS A1774 ( 4.7A) | 1.21A | 1ri4A-2cn3A:undetectable | 1ri4A-2cn3A:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hp3 | IDS-EPIMERASE (Agrobacteriumtumefaciens) |
PF03972(MmgE_PrpD) | 5 | GLY A 159GLY A 156ALA A 206PHE A 93TYR A 126 | None | 1.19A | 1ri4A-2hp3A:undetectable | 1ri4A-2hp3A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iu8 | UDP-3-O-[3-HYDROXYMYRISTOYL] GLUCOSAMINEN-ACYLTRANSFERASE (Chlamydiatrachomatis) |
PF00132(Hexapep)PF04613(LpxD) | 5 | GLY A 262GLY A 280ALA A 264ASP A 224GLN A 278 | PLM A1349 ( 4.2A)PLM A1349 (-3.7A)PLM A1349 (-3.2A)NoneNone | 1.14A | 1ri4A-2iu8A:undetectable | 1ri4A-2iu8A:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2myu | GLUTAREDOXINARSENATE REDUCTASE (Synechocystissp. PCC 6803) |
PF01451(LMWPc) | 5 | GLY A 26ILE A 30ALA A 31SER A 131PHE A 21 | None | 0.97A | 1ri4A-2myuA:undetectable | 1ri4A-2myuA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o57 | PUTATIVE SARCOSINEDIMETHYLGLYCINEMETHYLTRANSFERASE (Galdieriasulphuraria) |
PF08241(Methyltransf_11) | 5 | GLY A 90GLY A 92ILE A 113ALA A 114GLN A 157 | None | 0.95A | 1ri4A-2o57A:16.3 | 1ri4A-2o57A:25.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oap | TYPE II SECRETIONSYSTEM PROTEIN (Archaeoglobusfulgidus) |
PF00437(T2SSE) | 5 | GLY 1 357ILE 1 337PHE 1 261SER 1 262TYR 1 361 | None | 1.05A | 1ri4A-2oap1:undetectable | 1ri4A-2oap1:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oua | SERINE PROTEASE (Nocardiopsisalba) |
PF00089(Trypsin) | 6 | GLY A 19GLY A 44ILE A 17TYR A 120PHE A 199SER A 139 | None | 1.41A | 1ri4A-2ouaA:undetectable | 1ri4A-2ouaA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pnc | COPPER AMINEOXIDASE, LIVERISOZYME (Bos taurus) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 5 | GLY A 368ALA A 523SER A 643PHE A 388SER A 386 | None | 1.21A | 1ri4A-2pncA:undetectable | 1ri4A-2pncA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2po4 | VIRION RNAPOLYMERASE (Escherichiavirus N4) |
no annotation | 5 | GLY A 574GLY A1042ILE A 980SER A 808TYR A 811 | None | 1.20A | 1ri4A-2po4A:undetectable | 1ri4A-2po4A:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q27 | OXALYL-COADECARBOXYLASE (Escherichiacoli) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | GLY A 426ILE A 431ALA A 60PHE A 452SER A 453 | NoneNoneNoneTPP A3001 (-4.4A)None | 1.00A | 1ri4A-2q27A:3.5 | 1ri4A-2q27A:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qe6 | UNCHARACTERIZEDPROTEIN TFU_2867 (Thermobifidafusca) |
PF04672(Methyltransf_19) | 5 | GLY A 84GLY A 86ILE A 111ASP A 135TYR A 168 | SAM A 400 (-3.4A)SAM A 400 ( 3.2A)SAM A 400 (-3.7A)SAM A 400 (-3.4A)SAM A 400 ( 4.5A) | 0.60A | 1ri4A-2qe6A:13.7 | 1ri4A-2qe6A:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qua | EXTRACELLULAR LIPASE (Serratiamarcescens) |
no annotation | 5 | GLY A 198ILE A 136ALA A 135GLN A 230SER A 231 | None | 1.11A | 1ri4A-2quaA:undetectable | 1ri4A-2quaA:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v84 | SPERMIDINE/PUTRESCINE ABC TRANSPORTER,PERIPLASMIC BINDINGPROTEIN (Treponemapallidum) |
PF13416(SBP_bac_8) | 5 | LYS A 305GLY A 115GLY A 208ASP A 226TYR A 294 | MES A1326 (-2.9A)NoneNoneNoneNone | 1.20A | 1ri4A-2v84A:undetectable | 1ri4A-2v84A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdw | VACCINIA VIRUSCAPPING ENZYME D1SUBUNIT (Vaccinia virus) |
PF03291(Pox_MCEL) | 5 | LYS A 573GLY A 600GLN A 678PHE A 679TYR A 683 | SAH A1846 (-2.9A)SAH A1846 (-3.2A)NoneSAH A1846 (-4.9A)SAH A1846 ( 3.7A) | 0.45A | 1ri4A-2vdwA:27.1 | 1ri4A-2vdwA:25.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhl | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Bacillussubtilis) |
PF01979(Amidohydro_1) | 5 | GLY A 58GLY A 91ALA A 128ASP A 365SER A 344 | None | 1.11A | 1ri4A-2vhlA:undetectable | 1ri4A-2vhlA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsa | MOSQUITOCIDAL TOXIN (Lysinibacillussphaericus) |
PF05588(Botulinum_HA-17)PF14200(RicinB_lectin_2) | 5 | GLY A 178ILE A 173ALA A 175PHE A 140SER A 142 | None | 1.17A | 1ri4A-2vsaA:undetectable | 1ri4A-2vsaA:14.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wkn | FORMAMIDASE (Delftiaacidovorans) |
PF03069(FmdA_AmdA) | 5 | GLY A 106GLY A 264ILE A 52ASP A 60SER A 127 | None ZN A 412 ( 4.6A)NoneNoneNone | 1.14A | 1ri4A-2wknA:undetectable | 1ri4A-2wknA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yeq | ALKALINE PHOSPHATASED (Bacillussubtilis) |
PF09423(PhoD)PF16655(PhoD_N) | 5 | GLY A 416GLY A 414ASP A 500SER A 499PHE A 461 | NoneNoneNoneNoneEDO A 533 ( 4.2A) | 1.06A | 1ri4A-2yeqA:undetectable | 1ri4A-2yeqA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bkx | SAM-DEPENDENTMETHYLTRANSFERASE (Lactobacillusparacasei) |
PF13649(Methyltransf_25) | 6 | GLY A 50GLY A 52ILE A 75ALA A 76SER A 130TYR A 133 | None | 0.96A | 1ri4A-3bkxA:13.1 | 1ri4A-3bkxA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bus | METHYLTRANSFERASE (Lechevalieriaaerocolonigenes) |
PF08241(Methyltransf_11) | 5 | GLY A 69GLY A 71ILE A 92ASP A 119SER A 138 | SAH A 274 (-3.1A)SAH A 274 (-3.4A)SAH A 274 (-4.0A)SAH A 274 (-3.6A)None | 0.48A | 1ri4A-3busA:17.2 | 1ri4A-3busA:26.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bxo | N,N-DIMETHYLTRANSFERASE (Streptomycesvenezuelae) |
PF13649(Methyltransf_25) | 5 | GLY A 48ASP A 89PHE A 106SER A 108TYR A 111 | SAM A 238 ( 3.7A)SAM A 238 (-3.0A)UPP A 239 ( 3.6A)SAM A 238 (-3.2A)SAM A 238 ( 4.7A) | 0.98A | 1ri4A-3bxoA:18.3 | 1ri4A-3bxoA:24.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d2l | SAM-DEPENDENTMETHYLTRANSFERASE (Exiguobacteriumsibiricum) |
PF13649(Methyltransf_25) | 5 | GLY A 40GLY A 42ASP A 86SER A 105TYR A 108 | None | 1.08A | 1ri4A-3d2lA:19.2 | 1ri4A-3d2lA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d7n | FLAVODOXIN,WRBA-LIKE PROTEIN (Agrobacteriumfabrum) |
PF03358(FMN_red) | 5 | GLY A 96GLY A 61ALA A 24TYR A 176PHE A 94 | None | 1.13A | 1ri4A-3d7nA:undetectable | 1ri4A-3d7nA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ecq | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Streptococcuspneumoniae) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 5 | GLY A 656GLY A 619ILE A 671ALA A 622SER A 654 | None | 1.12A | 1ri4A-3ecqA:undetectable | 1ri4A-3ecqA:12.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ezo | MALONYL COA-ACYLCARRIER PROTEINTRANSACYLASE (Burkholderiapseudomallei) |
PF00698(Acyl_transf_1) | 5 | GLY A 168GLY A 128ILE A 166ALA A 130SER A 199 | None | 1.09A | 1ri4A-3ezoA:undetectable | 1ri4A-3ezoA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f6g | ALPHA-ISOPROPYLMALATE SYNTHASE (Leptospirainterrogans) |
no annotation | 5 | GLY B 428GLY B 426ILE B 399ALA B 409TYR B 430 | None | 0.87A | 1ri4A-3f6gB:undetectable | 1ri4A-3f6gB:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fsr | NADP-DEPENDENTALCOHOLDEHYDROGENASE (Clostridiumbeijerinckii;Thermoanaerobacterbrockii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 158GLY A 182ILE A 164ALA A 186SER A 263 | None | 1.02A | 1ri4A-3fsrA:7.7 | 1ri4A-3fsrA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4e | ISOCITRATE LYASE (Burkholderiapseudomallei) |
PF00463(ICL) | 5 | GLY A 273ALA A 228ASP A 281GLN A 305TYR A 279 | None | 1.19A | 1ri4A-3i4eA:undetectable | 1ri4A-3i4eA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3if6 | OXA-46 OXACILLINASE (Pseudomonasaeruginosa) |
PF00905(Transpeptidase) | 5 | GLY C 215GLY C 218ILE C 160ALA C 71ASP C 161 | None | 0.92A | 1ri4A-3if6C:undetectable | 1ri4A-3if6C:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k6r | PUTATIVE TRANSFERASEPH0793 (Pyrococcushorikoshii) |
PF02475(Met_10) | 5 | GLY A 135GLY A 137ILE A 154ALA A 153PHE A 163 | None | 1.07A | 1ri4A-3k6rA:14.4 | 1ri4A-3k6rA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3krt | CROTONYL COAREDUCTASE (Streptomycescoelicolor) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 6 | GLY A 122GLY A 179ILE A 34ALA A 33PHE A 174SER A 86 | None | 1.27A | 1ri4A-3krtA:6.3 | 1ri4A-3krtA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ksu | 3-OXOACYL-ACYLCARRIER PROTEINREDUCTASE (Oenococcus oeni) |
PF13561(adh_short_C2) | 5 | GLY A 139ILE A 92ALA A 93TYR A 4GLN A 181 | None | 1.21A | 1ri4A-3ksuA:7.2 | 1ri4A-3ksuA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8d | METHYLTRANSFERASE (Bacillusthuringiensis) |
PF08241(Methyltransf_11) | 5 | GLY A 61GLY A 63ILE A 83ASP A 106SER A 125 | None | 0.70A | 1ri4A-3l8dA:15.0 | 1ri4A-3l8dA:25.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mk3 | 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE (Salmonellaenterica) |
no annotation | 5 | GLY A 130GLY A 134ALA A 138ASP A 32SER A 29 | None | 1.08A | 1ri4A-3mk3A:undetectable | 1ri4A-3mk3A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pg5 | UNCHARACTERIZEDPROTEIN (Corynebacteriumdiphtheriae) |
PF13614(AAA_31) | 5 | GLY A 175ILE A 157ALA A 145PHE A 179SER A 5 | None | 1.10A | 1ri4A-3pg5A:undetectable | 1ri4A-3pg5A:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t2y | SULFIDE-QUINONEREDUCTASE, PUTATIVE (Acidithiobacillusferrooxidans) |
PF07992(Pyr_redox_2) | 5 | GLY A 10GLY A 12ALA A 17SER A 34PHE A 41 | FAD A 500 (-3.1A)FAD A 500 (-3.7A)NoneFAD A 500 (-3.4A)None | 1.10A | 1ri4A-3t2yA:2.8 | 1ri4A-3t2yA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsc | PUTATIVEOXIDOREDUCTASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | GLY A 14ILE A 39ALA A 40ASP A 77GLN A 19 | NAD A 274 (-3.2A)NAD A 274 (-3.8A)NoneNAD A 274 (-3.4A)NAD A 274 (-3.3A) | 1.15A | 1ri4A-3tscA:6.2 | 1ri4A-3tscA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u1k | POLYRIBONUCLEOTIDENUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL (Homo sapiens) |
PF00013(KH_1)PF01138(RNase_PH)PF03725(RNase_PH_C)PF03726(PNPase) | 5 | GLY A 553GLY A 549ILE A 236ALA A 233ASP A 240 | None | 1.10A | 1ri4A-3u1kA:undetectable | 1ri4A-3u1kA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vas | PUTATIVE ADENOSINEKINASE (Schistosomamansoni) |
PF00294(PfkB) | 5 | GLY A 221ILE A 218SER A 216PHE A 169TYR A 165 | NoneNoneNoneADN A 401 (-3.7A)None | 1.19A | 1ri4A-3vasA:2.6 | 1ri4A-3vasA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vxi | DYP (Bjerkanderaadusta) |
PF04261(Dyp_perox) | 5 | GLY A 424GLY A 425ALA A 98ASP A 104GLN A 150 | None | 0.99A | 1ri4A-3vxiA:undetectable | 1ri4A-3vxiA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ayi | LIPOPROTEIN GNA1870CCOMPND 7 (Neisseriameningitidis) |
PF08794(Lipoprot_C) | 5 | GLY D 318GLY D 219ILE D 316ALA D 221GLN D 320 | None | 1.06A | 1ri4A-4ayiD:undetectable | 1ri4A-4ayiD:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1o | BETA-XYLOSIDASE (Parageobacillusthermoglucosidasius) |
PF03512(Glyco_hydro_52) | 5 | GLY A 598GLY A 534ILE A 596ALA A 595PHE A 617 | None | 1.04A | 1ri4A-4c1oA:undetectable | 1ri4A-4c1oA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c4a | PROTEIN ARGININEN-METHYLTRANSFERASE7 (Mus musculus) |
PF06325(PrmA) | 5 | GLY A 72ILE A 119ALA A 92ASP A 133PHE A 96 | SAH A1689 (-3.0A)NoneNoneNoneNone | 1.17A | 1ri4A-4c4aA:8.9 | 1ri4A-4c4aA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ckb | MRNA-CAPPING ENZYMECATALYTIC SUBUNIT (Vaccinia virus) |
PF03291(Pox_MCEL)PF10640(Pox_ATPase-GT) | 5 | LYS A 573GLY A 600GLN A 678PHE A 679TYR A 683 | SAH A1845 (-2.8A)SAH A1845 (-3.4A)NoneNoneSAH A1845 (-3.5A) | 0.38A | 1ri4A-4ckbA:27.5 | 1ri4A-4ckbA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f4w | DNA POLYMERASE IV (Sulfolobusacidocaldarius;Sulfolobussolfataricus) |
PF00817(IMS)PF11798(IMS_HHH) | 5 | GLY A 165GLY A 144ILE A 167ALA A 146SER A 159 | None | 1.13A | 1ri4A-4f4wA:undetectable | 1ri4A-4f4wA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g68 | ABC TRANSPORTER (Caldanaerobius) |
PF01547(SBP_bac_1) | 5 | GLY B 304ILE B 302ALA B 377SER B 374TYR B 301 | NoneNoneXYP B 802 (-3.4A)NoneNone | 1.01A | 1ri4A-4g68B:undetectable | 1ri4A-4g68B:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hn3 | LMO1757 PROTEIN (Listeriamonocytogenes) |
PF07537(CamS) | 5 | GLY A 226GLY A 234ALA A 232ASP A 229SER A 170 | None | 1.18A | 1ri4A-4hn3A:undetectable | 1ri4A-4hn3A:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hyk | DNA POLYMERASE IV (Sulfolobusacidocaldarius) |
PF00817(IMS)PF11798(IMS_HHH) | 5 | GLY A 165GLY A 144ILE A 167ALA A 146SER A 159 | None | 1.15A | 1ri4A-4hykA:undetectable | 1ri4A-4hykA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jx8 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] FABI (Escherichiacoli) |
PF13561(adh_short_C2) | 5 | GLY A 93ILE A 115ALA A 95PHE A 124SER A 123 | NAD A 302 (-3.9A)NoneAE6 A 301 (-3.7A)NoneNone | 1.10A | 1ri4A-4jx8A:5.7 | 1ri4A-4jx8A:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ldq | METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE (Homo sapiens) |
PF01008(IF-2B) | 5 | GLY A 144GLY A 147ALA A 279TYR A 178SER A 187 | None | 0.99A | 1ri4A-4ldqA:6.0 | 1ri4A-4ldqA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lq1 | 1,4-ALPHA-GLUCANBRANCHING ENZYMEGLGB (Escherichiacoli) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C)PF02922(CBM_48) | 5 | GLY A 668GLY A 706ILE A 702ALA A 703ASP A 700 | None | 1.17A | 1ri4A-4lq1A:undetectable | 1ri4A-4lq1A:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m73 | METHYLTRANSFERASEMPPJ (Streptomyceshygroscopicus) |
PF13649(Methyltransf_25) | 5 | GLY A 166GLY A 168ILE A 190ALA A 191ASP A 217 | SAH A 401 (-3.4A)SAH A 401 (-3.5A)SAH A 401 (-3.8A)SAH A 401 (-3.5A)SAH A 401 ( 3.7A) | 0.33A | 1ri4A-4m73A:15.5 | 1ri4A-4m73A:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m85 | N-ACETYLTRANSFERASE (Staphylococcusaureus) |
PF00583(Acetyltransf_1) | 5 | ILE A 113TYR A 111GLN A 55PHE A 53TYR A 73 | None | 1.17A | 1ri4A-4m85A:undetectable | 1ri4A-4m85A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mwz | PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE,PUTATIVE (Plasmodiumvivax) |
PF13649(Methyltransf_25) | 5 | GLY A 60GLY A 62ILE A 83ASP A 107SER A 126 | SAM A 301 (-3.7A)SAM A 301 ( 3.8A)SAM A 301 (-3.7A)SAM A 301 (-3.5A)SAM A 301 (-3.2A) | 0.52A | 1ri4A-4mwzA:16.0 | 1ri4A-4mwzA:26.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n72 | PYRUVATEDEHYDROGENASE(DIHYDROLIPOYLTRANSACETYLASE COMPONENT) (Escherichiacoli) |
PF00198(2-oxoacid_dh) | 5 | GLY A 545GLY A 496ILE A 493TYR A 492GLN A 543 | None | 1.13A | 1ri4A-4n72A:undetectable | 1ri4A-4n72A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ofl | EXTRACYTOPLASMICNICKEL-BINDINGPROTEIN YPYNTA (Yersinia pestis) |
PF00496(SBP_bac_5) | 5 | GLY A 149GLY A 151ILE A 132ASP A 81PHE A 17 | None | 1.09A | 1ri4A-4oflA:undetectable | 1ri4A-4oflA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qed | ELXO (Staphylococcusepidermidis) |
PF13561(adh_short_C2) | 5 | GLY A 143GLY A 154ILE A 141ASP A 243SER A 139 | None | 1.20A | 1ri4A-4qedA:5.3 | 1ri4A-4qedA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rhh | BETA-XYLOSIDASE (Geobacillusstearothermophilus) |
PF03512(Glyco_hydro_52) | 5 | GLY A 576GLY A 512ILE A 574ALA A 573PHE A 595 | None | 1.07A | 1ri4A-4rhhA:undetectable | 1ri4A-4rhhA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ua3 | UNCHARACTERIZEDN-ACETYLTRANSFERASEC825.04C (Schizosaccharomycespombe) |
PF00583(Acetyltransf_1) | 5 | GLY A 100ILE A 88TYR A 41GLN A 51TYR A 87 | None | 1.20A | 1ri4A-4ua3A:undetectable | 1ri4A-4ua3A:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubt | ACETYL-COAACETYLTRANSFERASEFADA5 (Mycobacteriumtuberculosis) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 6 | GLY A 57GLY A 119ILE A 116ALA A 254GLN A 62SER A 71 | None | 0.98A | 1ri4A-4ubtA:undetectable | 1ri4A-4ubtA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udj | UHGB_MP (unculturedorganism) |
PF04041(Glyco_hydro_130) | 5 | GLY A 152ILE A 180ALA A 215SER A 183TYR A 182 | None | 0.98A | 1ri4A-4udjA:undetectable | 1ri4A-4udjA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uds | MBDR REGULATOR (Azoarcus sp.CIB) |
PF00440(TetR_N) | 5 | GLY A 46ILE A 52ALA A 42TYR A 55SER A 16 | None | 1.17A | 1ri4A-4udsA:undetectable | 1ri4A-4udsA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x33 | PROTEIN ATS1 (Saccharomycescerevisiae) |
PF00415(RCC1) | 5 | GLY B 16GLY B 18SER B 48GLN B 27SER B 29 | NoneDXE B 406 (-4.5A)NoneNoneNone | 1.12A | 1ri4A-4x33B:undetectable | 1ri4A-4x33B:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xb6 | ALPHA-D-RIBOSE1-METHYLPHOSPHONATE5-TRIPHOSPHATESYNTHASE SUBUNITPHNIALPHA-D-RIBOSE1-METHYLPHOSPHONATE5-PHOSPHATE C-PLYASE (Escherichiacoli;Escherichiacoli) |
PF05861(PhnI)PF06007(PhnJ) | 5 | ILE D 188ALA D 172ASP D 192TYR D 250PHE C 337 | None | 1.10A | 1ri4A-4xb6D:undetectable | 1ri4A-4xb6D:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xpu | ENDONUCLEASE V (Escherichiacoli) |
PF04493(Endonuclease_5) | 5 | GLY A 106GLY A 177ILE A 174ALA A 185SER A 108 | None | 1.19A | 1ri4A-4xpuA:undetectable | 1ri4A-4xpuA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yac | CALPHA-DEHYDROGENASE (Sphingobium sp.SYK-6) |
PF00106(adh_short) | 5 | GLY A 13GLY A 15ILE A 39ASP A 64GLN A 22 | NAI A 500 (-3.4A)NAI A 500 ( 4.2A)NAI A 500 (-3.8A)NAI A 500 (-3.6A)None | 0.91A | 1ri4A-4yacA:6.9 | 1ri4A-4yacA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zju | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Acinetobacterbaumannii) |
PF13561(adh_short_C2) | 5 | GLY A 95ILE A 117ALA A 97PHE A 126SER A 125 | NAD A 300 (-3.7A)NoneNoneNoneNone | 1.21A | 1ri4A-4zjuA:5.1 | 1ri4A-4zjuA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a55 | ENDO-ALPHA-N-ACETYLGALACTOSAMINIDASE (Streptococcuspneumoniae) |
PF12905(Glyco_hydro_101)PF17451(Glyco_hyd_101C) | 5 | GLY A 656GLY A 619ILE A 671ALA A 622SER A 654 | None | 1.13A | 1ri4A-5a55A:undetectable | 1ri4A-5a55A:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dz6 | POLYKETIDEBIOSYNTHESIS MALONYLCOA-ACYL CARRIERPROTEIN TRANSACYLASEPKSC (Bacillussubtilis) |
PF00698(Acyl_transf_1) | 5 | GLY A 162GLY A 123ILE A 160ALA A 125SER A 194 | None | 1.14A | 1ri4A-5dz6A:undetectable | 1ri4A-5dz6A:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dz7 | POLYKETIDEBIOSYNTHESIS PROTEINPKSE (Bacillussubtilis) |
PF00698(Acyl_transf_1) | 5 | GLY A 162GLY A 123ILE A 160ALA A 125SER A 194 | None | 1.12A | 1ri4A-5dz7A:undetectable | 1ri4A-5dz7A:19.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e9j | MRNA CAP GUANINE-N7METHYLTRANSFERASE,MRNA CAP GUANINE-N7METHYLTRANSFERASE (Homo sapiens) |
PF03291(Pox_MCEL) | 10 | LYS A 180GLY A 205GLY A 207ILE A 228ALA A 229ASP A 261SER A 262GLN A 284PHE A 285TYR A 289 | SAH A 501 (-2.3A)SAH A 501 (-3.4A)SAH A 501 (-3.4A)SAH A 501 (-3.8A)SAH A 501 ( 4.2A)SAH A 501 (-3.5A)SAH A 501 (-4.0A)NoneNoneSAH A 501 (-4.0A) | 0.52A | 1ri4A-5e9jA:31.7 | 1ri4A-5e9jA:32.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9w | MRNA CAP GUANINE-N7METHYLTRANSFERASE (Homo sapiens) |
PF03291(Pox_MCEL) | 10 | LYS A 180GLY A 205GLY A 207ILE A 228ALA A 229ASP A 261SER A 262GLN A 284PHE A 285TYR A 289 | SAH A 500 (-2.6A)SAH A 500 (-3.8A)SAH A 500 (-3.5A)SAH A 500 (-3.7A)SAH A 500 ( 3.9A)SAH A 500 (-3.6A)SAH A 500 (-4.1A)NoneNoneSAH A 500 (-4.0A) | 0.53A | 1ri4A-5e9wA:32.2 | 1ri4A-5e9wA:29.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i32 | AQUAPORIN TIP2-1 (Arabidopsisthaliana) |
PF00230(MIP) | 5 | GLY A 194SER A 201TYR A 217PHE A 191SER A 192 | None | 1.15A | 1ri4A-5i32A:undetectable | 1ri4A-5i32A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jvk | UNCHARACTERIZEDPROTEIN (Bacteroidescellulosilyticus) |
no annotation | 5 | GLY A 284GLY A 289ALA A 294SER A 312TYR A 311 | None | 1.02A | 1ri4A-5jvkA:undetectable | 1ri4A-5jvkA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kf7 | BIFUNCTIONAL PROTEINPUTA (Sinorhizobiummeliloti) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 5 | GLY A 259ILE A 247ALA A 250SER A 217TYR A 218 | None | 1.15A | 1ri4A-5kf7A:undetectable | 1ri4A-5kf7A:13.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lj6 | MACROLIDE EXPORTATP-BINDING/PERMEASEPROTEIN MACB (Aggregatibacteractinomycetemcomitans) |
no annotation | 5 | GLY A 532GLY A 535ILE A 277SER A 281SER A 617 | None | 1.14A | 1ri4A-5lj6A:undetectable | 1ri4A-5lj6A:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mg5 | 2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESISPROTEIN PHLC (Pseudomonasprotegens) |
no annotation | 5 | GLY C 114GLY C 216ALA C 214PHE C 95SER C 91 | None | 1.15A | 1ri4A-5mg5C:undetectable | 1ri4A-5mg5C:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5svc | ACETONE CARBOXYLASEALPHA SUBUNIT (Xanthobacterautotrophicus) |
PF02538(Hydantoinase_B) | 5 | GLY A 517GLY A 464ALA A 433SER A 508SER A 473 | None | 1.14A | 1ri4A-5svcA:undetectable | 1ri4A-5svcA:16.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uin | FORMYLTRANSFERASE (Salmonellaenterica) |
PF00551(Formyl_trans_N)PF13637(Ank_4) | 5 | LYS A 149GLY A 304ASP A 371TYR A 372PHE A 42 | None | 1.21A | 1ri4A-5uinA:undetectable | 1ri4A-5uinA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5was | HOMOSERINE KINASE (Corynebacteriumglutamicum) |
no annotation | 5 | GLY A 101GLY A 99ALA A 20SER A 144GLN A 96 | PO4 A 401 (-4.0A)PO4 A 401 ( 4.3A)NoneNoneNone | 0.89A | 1ri4A-5wasA:undetectable | 1ri4A-5wasA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wat | HOMOSERINE KINASE (Corynebacteriumglutamicum) |
no annotation | 5 | GLY A 101GLY A 99ALA A 20SER A 144GLN A 96 | PO4 A 401 (-3.9A)PO4 A 402 (-3.4A)PO4 A 403 ( 4.4A)NoneNone | 0.64A | 1ri4A-5watA:undetectable | 1ri4A-5watA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y10 | MEMBRANEGLYCOPROTEINPOLYPROTEIN (SFTSphlebovirus) |
PF07243(Phlebovirus_G1) | 5 | GLY C 76GLY C 28ILE C 55GLN C 79SER C 169 | None | 1.11A | 1ri4A-5y10C:undetectable | 1ri4A-5y10C:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z6o | PROTEASE (Penicilliumcyclopium) |
no annotation | 5 | GLY A 209GLY A 226ILE A 184SER A 187TYR A 206 | NonePMS A 302 (-3.6A)NoneNoneNone | 1.05A | 1ri4A-5z6oA:2.0 | 1ri4A-5z6oA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6apg | DISD PROTEIN (Sorangiumcellulosum) |
no annotation | 5 | GLY A 161GLY A 122ILE A 159ALA A 124SER A 192 | None | 1.17A | 1ri4A-6apgA:undetectable | 1ri4A-6apgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cbo | C-6'AMINOTRANSFERASE (Micromonosporaechinospora) |
no annotation | 5 | GLY A 244GLY A 102ILE A 229ALA A 110GLN A 93 | None | 1.10A | 1ri4A-6cboA:undetectable | 1ri4A-6cboA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dd6 | PHOTOLYASE PHRB (Agrobacteriumtumefaciens) |
no annotation | 5 | GLY A 275ALA A 234ASP A 281GLN A 11SER A 13 | None | 1.18A | 1ri4A-6dd6A:2.0 | 1ri4A-6dd6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 9wga | WHEAT GERM LECTIN (Triticumaestivum) |
PF00187(Chitin_bind_1) | 5 | GLY A 108GLY A 90ILE A 87GLN A 106SER A 105 | None | 0.99A | 1ri4A-9wgaA:undetectable | 1ri4A-9wgaA:20.88 |