SIMILAR PATTERNS OF AMINO ACIDS FOR 1R15_F_NCAF369
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ciy | CRYIA(A) (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 3 | GLU A 274ASN A 270TRP A 226 | None | 1.19A | 1r15F-1ciyA:undetectable | 1r15F-1ciyA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1coy | CHOLESTEROL OXIDASE (Brevibacteriumsterolicum) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 3 | GLU A 384ASN A 382TRP A 401 | None | 0.80A | 1r15F-1coyA:undetectable | 1r15F-1coyA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fok | PROTEIN (FOKIRESTRICTIONENDONUCLEASE) (Planomicrobiumokeanokoites) |
PF02980(FokI_C)PF02981(FokI_N)PF09254(Endonuc-FokI_C)PF16902(Type2_restr_D3) | 3 | GLU A 214ASN A 218TRP A 219 | None | 0.94A | 1r15F-1fokA:2.8 | 1r15F-1fokA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h0h | FORMATEDEHYDROGENASESUBUNIT ALPHAFORMATEDEHYDROGENASESUBUNIT BETA (Desulfovibriogigas;Desulfovibriogigas) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4)PF13247(Fer4_11) | 3 | GLU A 41ASN A 39TRP B 24 | None | 0.92A | 1r15F-1h0hA:undetectable | 1r15F-1h0hA:13.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h67 | CALPONIN ALPHA (Gallus gallus) |
PF00307(CH) | 3 | GLU A 86ASN A 76TRP A 82 | None | 1.20A | 1r15F-1h67A:undetectable | 1r15F-1h67A:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqe | HISTAMINEN-METHYLTRANSFERASE (Homo sapiens) |
PF13489(Methyltransf_23) | 3 | GLU A 86ASN A 84TRP A 136 | None | 1.23A | 1r15F-1jqeA:undetectable | 1r15F-1jqeA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lwu | FIBRINOGEN GAMMACHAIN (Petromyzonmarinus) |
PF00147(Fibrinogen_C) | 3 | GLU C 271ASN C 317TRP C 208 | None | 1.06A | 1r15F-1lwuC:undetectable | 1r15F-1lwuC:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q9h | CELLOBIOHYDROLASE ICATALYTIC DOMAIN (Rasamsoniaemersonii) |
PF00840(Glyco_hydro_7) | 3 | GLU A 214ASN A 138TRP A 380 | None | 1.24A | 1r15F-1q9hA:undetectable | 1r15F-1q9hA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qnr | ENDO-1,4-B-D-MANNANASE (Trichodermareesei) |
PF00150(Cellulase) | 3 | GLU A 276ASN A 25TRP A 56 | GOL A 410 (-3.8A)NoneGOL A 411 (-4.0A) | 1.26A | 1r15F-1qnrA:2.0 | 1r15F-1qnrA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qqf | PROTEIN (COMPLEMENTC3DG) (Rattusnorvegicus) |
PF07678(A2M_comp)PF10569(Thiol-ester_cl) | 3 | GLU A1221ASN A1229TRP A1255 | None | 1.22A | 1r15F-1qqfA:undetectable | 1r15F-1qqfA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rh9 | ENDO-BETA-MANNANASE (Solanumlycopersicum) |
PF00150(Cellulase) | 3 | GLU A 318ASN A 53TRP A 88 | None | 1.23A | 1r15F-1rh9A:undetectable | 1r15F-1rh9A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sr4 | CYTOLETHALDISTENDING TOXINPROTEIN B ([Haemophilus]ducreyi) |
PF03372(Exo_endo_phos) | 3 | GLU B 42ASN B 46TRP B 93 | None | 1.25A | 1r15F-1sr4B:undetectable | 1r15F-1sr4B:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tmo | TRIMETHYLAMINEN-OXIDE REDUCTASE (Shewanellamassilia) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 3 | GLU A 662ASN A 470TRP A 727 | None | 1.25A | 1r15F-1tmoA:undetectable | 1r15F-1tmoA:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u5u | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
no annotation | 3 | GLU A 178ASN A 5TRP A 3 | None | 1.11A | 1r15F-1u5uA:undetectable | 1r15F-1u5uA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wtd | ECOO109IR (Escherichiacoli) |
PF14511(RE_EcoO109I) | 3 | GLU A 211ASN A 208TRP A 217 | None | 1.22A | 1r15F-1wtdA:2.6 | 1r15F-1wtdA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xc6 | BETA-GALACTOSIDASE (Penicillium sp.) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 3 | GLU A 323ASN A 321TRP A 273 | MAN A3007 (-3.5A)NoneNone | 1.17A | 1r15F-1xc6A:1.7 | 1r15F-1xc6A:12.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xkn | PUTATIVEPEPTIDYL-ARGININEDEIMINASE (Chlorobaculumtepidum) |
PF04371(PAD_porph) | 3 | GLU A 227ASN A 163TRP A 12 | None | 1.00A | 1r15F-1xknA:undetectable | 1r15F-1xknA:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a3l | AMP DEAMINASE (Arabidopsisthaliana) |
PF00962(A_deaminase) | 3 | GLU A 539ASN A 540TRP A 787 | None | 0.95A | 1r15F-2a3lA:undetectable | 1r15F-2a3lA:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cly | ATP SYNTHASE DCHAIN, MITOCHONDRIAL (Bos taurus) |
PF05873(Mt_ATP-synt_D) | 3 | GLU B 35ASN B 34TRP B 12 | None | 1.20A | 1r15F-2clyB:undetectable | 1r15F-2clyB:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d13 | HYPOTHETICAL PROTEINPH1257 (Pyrococcushorikoshii) |
PF01902(Diphthami_syn_2) | 3 | GLU A 168ASN A 165TRP A 156 | None | 1.10A | 1r15F-2d13A:2.9 | 1r15F-2d13A:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ejv | L-THREONINE3-DEHYDROGENASE (Thermusthermophilus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 3 | GLU A 130ASN A 131TRP A 292 | None | 1.28A | 1r15F-2ejvA:2.3 | 1r15F-2ejvA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ong | 4S-LIMONENE SYNTHASE (Mentha spicata) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | GLU A 430ASN A 448TRP A 433 | MN A 601 ( 4.9A)NoneNone | 1.26A | 1r15F-2ongA:undetectable | 1r15F-2ongA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rdy | BH0842 PROTEIN (Bacillushalodurans) |
PF14498(Glyco_hyd_65N_2) | 3 | GLU A 506ASN A 372TRP A 626 | None | 1.22A | 1r15F-2rdyA:undetectable | 1r15F-2rdyA:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rfz | CELLULOSE1,4-BETA-CELLOBIOSIDASE (Melanocarpusalbomyces) |
PF00840(Glyco_hydro_7) | 3 | GLU A 217ASN A 141TRP A 375 | CTR A 431 (-3.1A)NoneCTR A 431 (-4.0A) | 0.98A | 1r15F-2rfzA:undetectable | 1r15F-2rfzA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vyc | BIODEGRADATIVEARGININEDECARBOXYLASE (Escherichiacoli) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 3 | GLU A 332ASN A 329TRP A 528 | None | 1.14A | 1r15F-2vycA:undetectable | 1r15F-2vycA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wan | PULLULANASE (Bacillusacidopullulyticus) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 3 | GLU A 855ASN A 867TRP A 888 | None | 1.01A | 1r15F-2wanA:undetectable | 1r15F-2wanA:14.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wv9 | FLAVIVIRIN PROTEASENS2B REGULATORYSUBUNIT, FLAVIVIRINPROTEASE NS3CATALYTIC SUBUNIT (Murray Valleyencephalitisvirus) |
PF00271(Helicase_C)PF00949(Peptidase_S7)PF01002(Flavi_NS2B)PF07652(Flavi_DEAD) | 3 | GLU A 74ASN A 71TRP A 69 | None | 1.07A | 1r15F-2wv9A:undetectable | 1r15F-2wv9A:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xwb | COMPLEMENT C3BALPHA' CHAIN (Homo sapiens) |
PF00207(A2M)PF01759(NTR)PF07677(A2M_recep)PF07678(A2M_comp)PF10569(Thiol-ester_cl) | 3 | GLU B1199ASN B1207TRP B1233 | None | 1.25A | 1r15F-2xwbB:undetectable | 1r15F-2xwbB:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3j | PBP5 (Haemophilusinfluenzae) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 3 | GLU A 268ASN A 217TRP A 221 | None | 1.25A | 1r15F-3a3jA:undetectable | 1r15F-3a3jA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3act | CELLOBIOSEPHOSPHORYLASE (Cellulomonasgilvus) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 3 | GLU A 659ASN A 489TRP A 488 | BGC A2901 (-2.8A)None K A2903 (-4.0A) | 1.00A | 1r15F-3actA:undetectable | 1r15F-3actA:15.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bf0 | PROTEASE 4 (Escherichiacoli) |
PF01343(Peptidase_S49) | 3 | GLU A 292ASN A 307TRP A 301 | None | 1.07A | 1r15F-3bf0A:2.2 | 1r15F-3bf0A:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bma | D-ALANYL-LIPOTEICHOIC ACID SYNTHETASE (Streptococcuspneumoniae) |
PF04914(DltD) | 3 | GLU A 273ASN A 264TRP A 382 | None | 1.16A | 1r15F-3bmaA:1.5 | 1r15F-3bmaA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d3a | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF01301(Glyco_hydro_35) | 3 | GLU A 125ASN A 81TRP A 308 | None | 0.90A | 1r15F-3d3aA:2.9 | 1r15F-3d3aA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 3 | GLU A 178ASN A 5TRP A 3 | None | 1.09A | 1r15F-3dy5A:undetectable | 1r15F-3dy5A:13.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fzg | 16S RRNA METHYLASE (Escherichiacoli) |
PF07091(FmrO) | 3 | GLU A 129ASN A 126TRP A 125 | None | 1.01A | 1r15F-3fzgA:undetectable | 1r15F-3fzgA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i10 | PUTATIVEGLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Bacteroidesthetaiotaomicron) |
PF03009(GDPD)PF16387(DUF4996) | 3 | GLU A 73ASN A 144TRP A 245 | None | 1.05A | 1r15F-3i10A:undetectable | 1r15F-3i10A:21.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3i9k | ADP-RIBOSYL CYCLASE (Aplysiacalifornica) |
PF02267(Rib_hydrolayse) | 3 | GLU A 98ASN A 107TRP A 140 | None | 0.20A | 1r15F-3i9kA:39.4 | 1r15F-3i9kA:99.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0g | ISOPRENE SYNTHASE (Populus tremulax Populus alba) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | GLU A 423ASN A 441TRP A 426 | DST A 601 ( 3.3A)NoneNone | 1.13A | 1r15F-3n0gA:undetectable | 1r15F-3n0gA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ogr | BETA-GALACTOSIDASE (Trichodermareesei) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 3 | GLU A 322ASN A 320TRP A 272 | MAN A1029 (-3.5A)MAN A1031 (-3.9A)None | 1.22A | 1r15F-3ogrA:undetectable | 1r15F-3ogrA:13.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pz9 | MANNANENDO-1,4-BETA-MANNOSIDASE. GLYCOSYLHYDROLASE FAMILY 5 (Thermotogapetrophila) |
PF00150(Cellulase) | 3 | GLU A 317ASN A 43TRP A 73 | None | 1.18A | 1r15F-3pz9A:undetectable | 1r15F-3pz9A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qde | CELLOBIOSEPHOSPHORYLASE (Ruminiclostridiumthermocellum) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 3 | GLU A 646ASN A 482TRP A 481 | 144 A 813 (-3.5A)144 A 813 ( 4.9A)144 A 813 (-3.9A) | 1.07A | 1r15F-3qdeA:undetectable | 1r15F-3qdeA:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r1j | ALPHA-KETOGLUTARATE-DEPENDENT TAURINEDIOXYGENASE (Mycobacteriumavium) |
PF02668(TauD) | 3 | GLU A 282ASN A 278TRP A 150 | None | 1.18A | 1r15F-3r1jA:undetectable | 1r15F-3r1jA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rao | PUTATIVELUCIFERASE-LIKEMONOOXYGENASE (Bacillus cereus) |
PF00296(Bac_luciferase) | 3 | GLU A 278ASN A 296TRP A 252 | None | 1.19A | 1r15F-3raoA:undetectable | 1r15F-3raoA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rb9 | DNA POLYMERASE IIISUBUNIT BETA (Mycobacteriumtuberculosis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 3 | GLU A 213ASN A 32TRP A 28 | None | 1.28A | 1r15F-3rb9A:undetectable | 1r15F-3rb9A:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s9v | ABIETADIENESYNTHASE,CHLOROPLASTIC (Abies grandis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | GLU A 699ASN A 717TRP A 702 | None | 0.99A | 1r15F-3s9vA:undetectable | 1r15F-3s9vA:15.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sr7 | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Streptococcusmutans) |
PF01070(FMN_dh) | 3 | GLU A 147ASN A 143TRP A 160 | None | 1.07A | 1r15F-3sr7A:undetectable | 1r15F-3sr7A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t63 | PROTOCATECHUATE3,4-DIOXYGENASE BETACHAIN (Pseudomonasputida) |
PF00775(Dioxygenase_C)PF12391(PCDO_beta_N) | 3 | GLU M 499ASN M 497TRP M 315 | None | 1.24A | 1r15F-3t63M:undetectable | 1r15F-3t63M:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tlm | SARCOPLASMIC/ENDOPLASMIC RETICULUMCALCIUM ATPASE 1 (Bos taurus) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF08282(Hydrolase_3)PF13246(Cation_ATPase) | 3 | GLU A 917ASN A 918TRP A 831 | None | 1.25A | 1r15F-3tlmA:undetectable | 1r15F-3tlmA:12.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wfl | BETA-MANNANASE (Talaromycestrachyspermus) |
PF00150(Cellulase) | 3 | GLU A 309ASN A 57TRP A 88 | TRS A 402 (-2.8A)NoneGOL A 404 (-4.0A) | 1.19A | 1r15F-3wflA:2.0 | 1r15F-3wflA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wh9 | ENDO-BETA-1,4-MANNANASE (Aspergillusniger) |
PF00150(Cellulase) | 3 | GLU A 276ASN A 23TRP A 54 | TRS A 404 (-2.8A)NoneNone | 1.19A | 1r15F-3wh9A:2.0 | 1r15F-3wh9A:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ziz | GH5ENDO-BETA-1,4-MANNANASE (Podosporaanserina) |
PF00150(Cellulase) | 3 | GLU A 276ASN A 25TRP A 56 | TRS A1352 (-2.8A)NoneGOL A1351 (-3.9A) | 1.17A | 1r15F-3zizA:undetectable | 1r15F-3zizA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aq2 | HOMOGENTISATE1,2-DIOXYGENASE (Pseudomonasputida) |
PF04209(HgmA) | 3 | GLU A 200ASN A 146TRP A 114 | None | 1.21A | 1r15F-4aq2A:undetectable | 1r15F-4aq2A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4arx | PESTICIDAL CRYSTALPROTEIN CRY1AC (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 3 | GLU A 274ASN A 270TRP A 226 | None | 1.28A | 1r15F-4arxA:undetectable | 1r15F-4arxA:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4awe | ENDO-BETA-D-1,4-MANNANASE (Neurosporasitophila) |
PF00150(Cellulase) | 3 | GLU A 301ASN A 27TRP A 57 | TRS A1391 (-2.8A)NoneNone | 1.21A | 1r15F-4aweA:undetectable | 1r15F-4aweA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bko | PUTATIVE REDUCTASEBURPS305_1051 (Burkholderiapseudomallei) |
PF07055(Eno-Rase_FAD_bd)PF12241(Enoyl_reductase)PF12242(Eno-Rase_NADH_b) | 3 | GLU A 397ASN A 109TRP A 88 | None | 1.19A | 1r15F-4bkoA:2.5 | 1r15F-4bkoA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d5g | CYCLOHEXANE-1,2-DIONE HYDROLASE (Azoarcus sp.BH72) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 3 | GLU A 89ASN A 60TRP A 57 | None | 1.28A | 1r15F-4d5gA:2.3 | 1r15F-4d5gA:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4djh | KAPPA-TYPE OPIOIDRECEPTOR, LYSOZYME (Homo sapiens;Escherichiavirus T4) |
PF00001(7tm_1)PF00959(Phage_lysozyme) | 3 | GLU A1005ASN A1002TRP A1158 | None | 1.29A | 1r15F-4djhA:undetectable | 1r15F-4djhA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e9o | IMV MEMBRANE PROTEIN (Vaccinia virus) |
PF00194(Carb_anhydrase) | 3 | GLU X 90ASN X 92TRP X 182 | None | 1.21A | 1r15F-4e9oX:undetectable | 1r15F-4e9oX:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gbf | PHIKZ131 (Pseudomonasvirus phiKZ) |
no annotation | 3 | GLU A 406ASN A 422TRP A 424 | None | 1.28A | 1r15F-4gbfA:undetectable | 1r15F-4gbfA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4haq | GH7 FAMILY PROTEIN (Limnoriaquadripunctata) |
PF00840(Glyco_hydro_7) | 3 | GLU A 238ASN A 162TRP A 401 | CBI A 501 ( 4.3A)NoneCBI A 501 ( 3.8A) | 1.25A | 1r15F-4haqA:undetectable | 1r15F-4haqA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iug | BETA-GALACTOSIDASE A (Aspergillusoryzae) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 3 | GLU A 322ASN A 320TRP A 272 | CD A1114 ( 2.5A)MAN A1142 (-3.8A)None | 1.12A | 1r15F-4iugA:2.0 | 1r15F-4iugA:13.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j5t | MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE (Saccharomycescerevisiae) |
PF03200(Glyco_hydro_63)PF16923(Glyco_hydro_63N) | 3 | GLU A 771ASN A 772TRP A 710 | None | 1.01A | 1r15F-4j5tA:undetectable | 1r15F-4j5tA:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m1r | CELLULASE 5 (soil metagenome) |
PF00150(Cellulase) | 3 | GLU A 132ASN A 131TRP A 28 | TRS A 301 (-2.7A)TRS A 301 (-3.3A)TRS A 301 ( 4.8A) | 1.11A | 1r15F-4m1rA:undetectable | 1r15F-4m1rA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n02 | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Streptococcuspneumoniae) |
PF01070(FMN_dh) | 3 | GLU A 148ASN A 144TRP A 161 | NoneSO4 A 403 (-4.4A)None | 1.18A | 1r15F-4n02A:1.1 | 1r15F-4n02A:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nmn | REPLICATIVE DNAHELICASE (Aquifexaeolicus) |
PF00772(DnaB)PF03796(DnaB_C) | 3 | GLU A 26ASN A 61TRP A 56 | None | 1.24A | 1r15F-4nmnA:undetectable | 1r15F-4nmnA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o5p | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF09994(DUF2235) | 3 | GLU A 141ASN A 145TRP A 247 | None | 0.99A | 1r15F-4o5pA:undetectable | 1r15F-4o5pA:14.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oky | RESTRICTIONENDONUCLEASE PVURTS1I (Proteusvulgaris) |
no annotation | 3 | GLU C 228ASN C 217TRP C 205 | None | 1.08A | 1r15F-4okyC:undetectable | 1r15F-4okyC:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qp0 | ENDO-BETA-MANNANASE (Rhizomucormiehei) |
PF00150(Cellulase) | 3 | GLU A 293ASN A 25TRP A 55 | None | 1.23A | 1r15F-4qp0A:2.6 | 1r15F-4qp0A:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r2f | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Pseudarthrobacterchlorophenolicus) |
PF01547(SBP_bac_1) | 3 | GLU A 253ASN A 233TRP A 193 | None | 1.23A | 1r15F-4r2fA:undetectable | 1r15F-4r2fA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uqg | DNA POLYMERASE (Geobacillusstearothermophilus) |
PF00476(DNA_pol_A) | 3 | GLU A 340ASN A 339TRP A 455 | None | 1.03A | 1r15F-4uqgA:undetectable | 1r15F-4uqgA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x04 | SOLUTE BINDINGPROTEIN (Citrobacterkoseri) |
PF03480(DctP) | 3 | GLU A 240ASN A 42TRP A 275 | BDP A 401 (-2.9A)NoneNone | 1.26A | 1r15F-4x04A:undetectable | 1r15F-4x04A:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x28 | ACYL-COADEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 3 | GLU A 343ASN A 288TRP A 284 | None | 1.04A | 1r15F-4x28A:undetectable | 1r15F-4x28A:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zzq | CELLULOSE1,4-BETA-CELLOBIOSIDASE (Dictyosteliumdiscoideum) |
PF00840(Glyco_hydro_7) | 3 | GLU A 216ASN A 140TRP A 382 | None | 1.20A | 1r15F-4zzqA:undetectable | 1r15F-4zzqA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5apa | ASPARTYL/ASPARAGINYLBETA-HYDROXYLASE (Homo sapiens) |
PF05118(Asp_Arg_Hydrox) | 3 | GLU A 617ASN A 618TRP A 625 | LMR A1760 ( 4.7A) NI A1759 ( 4.7A)LMR A1760 (-4.2A) | 1.22A | 1r15F-5apaA:undetectable | 1r15F-5apaA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c05 | PUTATIVEGAMMA-TERPINENESYNTHASE (Thymus vulgaris) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | GLU A 427ASN A 445TRP A 430 | GLU A 427 ( 0.6A)ASN A 445 ( 0.6A)TRP A 430 ( 0.5A) | 1.16A | 1r15F-5c05A:undetectable | 1r15F-5c05A:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5diz | PROTEINACEOUS RNASEP 2 (Arabidopsisthaliana) |
PF16953(PRORP)PF17177(PPR_long) | 3 | GLU A 405ASN A 409TRP A 380 | None | 1.25A | 1r15F-5dizA:undetectable | 1r15F-5dizA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dze | ENDO-GLUCANASE (Vitis vinifera) |
PF00722(Glyco_hydro_16) | 3 | GLU A 93ASN A 73TRP A 181 | BGC A 305 ( 2.5A)GLC A 301 (-3.3A)BGC A 305 (-3.2A) | 1.00A | 1r15F-5dzeA:undetectable | 1r15F-5dzeA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7v | LMO0181 PROTEIN (Listeriamonocytogenes) |
PF01547(SBP_bac_1) | 3 | GLU A 228ASN A 207TRP A 171 | None | 1.14A | 1r15F-5f7vA:undetectable | 1r15F-5f7vA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fui | ENDO-1,3-BETA-GLUCANASE, FAMILY GH16 (Zobelliagalactanivorans) |
PF03422(CBM_6) | 3 | GLU A 280ASN A 377TRP A 351 | GOL A 131 (-2.8A)GOL A 131 (-2.9A)None | 1.25A | 1r15F-5fuiA:undetectable | 1r15F-5fuiA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gsl | 778AA LONGHYPOTHETICALBETA-GALACTOSIDASE (Pyrococcushorikoshii) |
PF02449(Glyco_hydro_42) | 3 | GLU A 105ASN A 396TRP A 400 | PO4 A 802 (-2.8A)NoneNone | 1.22A | 1r15F-5gslA:1.9 | 1r15F-5gslA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gsm | EXO-BETA-D-GLUCOSAMINIDASE (Thermococcuskodakarensis) |
PF02449(Glyco_hydro_42) | 3 | GLU A 103ASN A 394TRP A 398 | GCS A 801 (-2.9A)NoneNone | 1.24A | 1r15F-5gsmA:2.5 | 1r15F-5gsmA:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gy0 | GLUCANASE (Ruminiclostridiumthermocellum) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 3 | GLU A 45ASN A 56TRP A 55 | None | 1.26A | 1r15F-5gy0A:undetectable | 1r15F-5gy0A:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2u | CELLULASE (soil metagenome) |
PF00150(Cellulase) | 3 | GLU A 143ASN A 142TRP A 43 | GOL A 402 (-2.9A)GOL A 402 (-3.5A)GOL A 401 (-4.3A) | 1.07A | 1r15F-5i2uA:undetectable | 1r15F-5i2uA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihr | PROBABLEBETA-GALACTOSIDASE A (Aspergillusniger) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 3 | GLU A 322ASN A 320TRP A 272 | MAN A1626 (-3.7A)MAN A1627 (-3.7A)None | 1.21A | 1r15F-5ihrA:undetectable | 1r15F-5ihrA:12.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iy9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1 (Homo sapiens) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 3 | GLU A 631ASN A 601TRP A 988 | None | 1.19A | 1r15F-5iy9A:undetectable | 1r15F-5iy9A:10.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jrl | DIPEPTIDYLAMINOPEPTIDASES/ACYLAMINOACYL-PEPTIDASES-LIKE PROTEIN (Sphingopyxisalaskensis) |
PF00326(Peptidase_S9) | 3 | GLU A 214ASN A 212TRP A 170 | None | 1.27A | 1r15F-5jrlA:3.5 | 1r15F-5jrlA:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mnd | GRANULIN (Cydia pomonellagranulovirus) |
PF00738(Polyhedrin) | 3 | GLU A 195ASN A 193TRP A 102 | None | 1.19A | 1r15F-5mndA:undetectable | 1r15F-5mndA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mpd | 26S PROTEASOMEREGULATORY SUBUNITRPN5 (Saccharomycescerevisiae) |
PF01399(PCI) | 3 | GLU P 319ASN P 323TRP P 338 | None | 0.99A | 1r15F-5mpdP:undetectable | 1r15F-5mpdP:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mx9 | PHOSPHATIDYLETHANOLAMINE TRANSFERASEMCR-2 (Escherichiacoli) |
PF00884(Sulfatase) | 3 | GLU A 453ASN A 499TRP A 497 | None | 1.26A | 1r15F-5mx9A:undetectable | 1r15F-5mx9A:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o5d | GLUCANASE (Trichodermaatroviride) |
no annotation | 3 | GLU A 217ASN A 141TRP A 376 | BTB A 604 ( 3.0A)BTB A 604 (-3.7A)BTB A 604 (-4.9A) | 1.27A | 1r15F-5o5dA:undetectable | 1r15F-5o5dA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u22 | N2152 (Neocallimastixfrontalis) |
PF01229(Glyco_hydro_39) | 3 | GLU A 155ASN A 154TRP A 118 | BTB A 501 (-2.8A)BTB A 501 (-3.4A)BTB A 501 (-3.6A) | 1.03A | 1r15F-5u22A:undetectable | 1r15F-5u22A:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur2 | BIFUNCTIONAL PROTEINPUTA (Bdellovibriobacteriovorus) |
PF00171(Aldedh)PF01619(Pro_dh) | 3 | GLU A 503ASN A 496TRP A 673 | None | 1.01A | 1r15F-5ur2A:undetectable | 1r15F-5ur2A:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5usl | IMV MEMBRANE PROTEIN (Vaccinia virus) |
no annotation | 3 | GLU X 90ASN X 92TRP X 182 | None | 1.18A | 1r15F-5uslX:undetectable | 1r15F-5uslX:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v89 | DCN1-LIKE PROTEIN 4 (Homo sapiens) |
PF03556(Cullin_binding) | 3 | GLU A 257ASN A 254TRP A 275 | None | 1.11A | 1r15F-5v89A:undetectable | 1r15F-5v89A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyb | - (-) |
no annotation | 3 | GLU A 247ASN A 245TRP A 281 | None | 1.07A | 1r15F-5xybA:undetectable | 1r15F-5xybA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z9s | GLYCOSYL HYDROLASEFAMILY 3 PROTEIN (Bifidobacteriumlongum) |
no annotation | 3 | GLU A 725ASN A 636TRP A 229 | None | 1.04A | 1r15F-5z9sA:undetectable | 1r15F-5z9sA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zu5 | ALGINATE LYASE (Vibriosplendidus) |
no annotation | 3 | GLU A 47ASN A 130TRP A 40 | None | 1.21A | 1r15F-5zu5A:undetectable | 1r15F-5zu5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zu6 | CBM32 DOMAIN (Vibrio) |
no annotation | 3 | GLU A 47ASN A 130TRP A 40 | None | 1.12A | 1r15F-5zu6A:undetectable | 1r15F-5zu6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eon | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
no annotation | 3 | GLU A 125ASN A 81TRP A 308 | None | 0.91A | 1r15F-6eonA:1.4 | 1r15F-6eonA:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gh2 | LAMINARIBIOSEPHOSPHORYLASE (Paenibacillussp. YM1) |
no annotation | 3 | GLU A 732ASN A 525TRP A 524 | G1P A1002 (-3.7A)NoneG1P A1002 (-3.3A) | 1.05A | 1r15F-6gh2A:undetectable | 1r15F-6gh2A:undetectable |