SIMILAR PATTERNS OF AMINO ACIDS FOR 1QU2_A_MRCA1993_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d8c MALATE SYNTHASE G

(Escherichia
coli) 		PF01274
(Malate_synthase) 		3 GLU A 595
TRP A 645
LYS A 506
 None
 0.96A 1qu2A-1d8cA:
0.0		 1qu2A-1d8cA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ex0 COAGULATION FACTOR
XIII A CHAIN

(Homo sapiens) 		PF00868
(Transglut_N)
PF00927
(Transglut_C)
PF01841
(Transglut_core) 		3 GLU A 377
TRP A 392
LYS A 504
 None
 1.32A 1qu2A-1ex0A:
undetectable		 1qu2A-1ex0A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g38 MODIFICATION
METHYLASE TAQI

(Thermus
aquaticus) 		PF07669
(Eco57I)
PF12950
(TaqI_C) 		3 GLU A 355
TRP A 352
LYS A 137
 None
 1.04A 1qu2A-1g38A:
undetectable		 1qu2A-1g38A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hsj FUSION PROTEIN
CONSISTING OF
STAPHYLOCOCCUS
ACCESSORY REGULATOR
PROTEIN R AND
MALTOSE BINDING
PROTEIN

(Escherichia
coli;
Staphylococcus
aureus) 		PF01547
(SBP_bac_1) 		3 GLU A 111
TRP A 230
LYS A 273
 GLC  A 672 (-2.7A)
GLC  A 672 (-4.2A)
None
 1.24A 1qu2A-1hsjA:
0.0		 1qu2A-1hsjA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hz4 MALT REGULATORY
PROTEIN

(Escherichia
coli) 		no annotation 3 GLU A  13
TRP A  46
LYS A  64
 None
 1.37A 1qu2A-1hz4A:
2.2		 1qu2A-1hz4A:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k32 TRICORN PROTEASE

(Thermoplasma
acidophilum) 		PF03572
(Peptidase_S41)
PF07676
(PD40)
PF14684
(Tricorn_C1)
PF14685
(Tricorn_PDZ) 		3 GLU A 312
TRP A  62
LYS A 324
 None
 0.79A 1qu2A-1k32A:
0.0		 1qu2A-1k32A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II

(Escherichia
coli) 		PF01075
(Glyco_transf_9) 		3 GLU A 190
TRP A  10
LYS A 167
 None
 1.25A 1qu2A-1pswA:
1.5		 1qu2A-1pswA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qlb FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Wolinella
succinogenes) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		3 GLU A 412
TRP A 397
LYS A 471
 None
 1.35A 1qu2A-1qlbA:
3.1		 1qu2A-1qlbA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qsa PROTEIN (SOLUBLE
LYTIC
TRANSGLYCOSYLASE
SLT70)

(Escherichia
coli) 		PF01464
(SLT)
PF14718
(SLT_L) 		3 GLU A 577
TRP A 321
LYS A 605
 None
 1.37A 1qu2A-1qsaA:
undetectable		 1qu2A-1qsaA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6z CHIMERA OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND ARGONAUTE 2

(Drosophila
melanogaster;
Escherichia
coli) 		no annotation 3 GLU P 110
TRP P 229
LYS P 272
 MAL  P 727 (-2.8A)
MAL  P 727 ( 4.7A)
None
 1.21A 1qu2A-1r6zP:
undetectable		 1qu2A-1r6zP:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ril RIBONUCLEASE H

(Thermus
thermophilus) 		PF00075
(RNase_H) 		3 GLU A  54
TRP A  22
LYS A  87
 None
 1.35A 1qu2A-1rilA:
undetectable		 1qu2A-1rilA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw9 CHONDROITIN AC LYASE

(Paenarthrobacter
aurescens) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		3 GLU A 407
TRP A 465
LYS A 749
 None
 0.82A 1qu2A-1rw9A:
3.1		 1qu2A-1rw9A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryy ALPHA-AMINO ACID
ESTER HYDROLASE

(Acetobacter
pasteurianus) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		3 GLU A 333
TRP A 368
LYS A 153
 None
 1.30A 1qu2A-1ryyA:
undetectable		 1qu2A-1ryyA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3h T-CELL RECEPTOR
ALPHA-CHAIN

(Mus musculus) 		PF07686
(V-set) 		3 GLU A  16
TRP A  13
LYS A  72
 None
 1.43A 1qu2A-1u3hA:
undetectable		 1qu2A-1u3hA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x3w PEPTIDE:N-GLYCANASE

(Saccharomyces
cerevisiae) 		PF03835
(Rad4) 		3 GLU A 238
TRP A 251
LYS A  94
 SUC  A1001 ( 3.0A)
SUC  A1001 ( 4.3A)
None
 1.27A 1qu2A-1x3wA:
undetectable		 1qu2A-1x3wA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y4c MALTOSE BINDING
PROTEIN FUSED WITH
DESIGNED HELICAL
PROTEIN

(Escherichia
coli) 		PF13416
(SBP_bac_8) 		3 GLU A 111
TRP A 230
LYS A 273
 GLC  A 371 (-2.9A)
GLC  A 371 ( 4.6A)
None
 1.23A 1qu2A-1y4cA:
3.1		 1qu2A-1y4cA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amx ADENOSINE DEAMINASE

(Plasmodium
yoelii) 		PF00962
(A_deaminase) 		3 GLU A 128
TRP A 124
LYS A  96
 None
 0.95A 1qu2A-2amxA:
undetectable		 1qu2A-2amxA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2esn PROBABLE
TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF00126
(HTH_1)
PF03466
(LysR_substrate) 		3 GLU A  88
TRP A  89
LYS A 300
 None
 1.19A 1qu2A-2esnA:
undetectable		 1qu2A-2esnA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f3o PYRUVATE
FORMATE-LYASE 2

(Archaeoglobus
fulgidus) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 GLU A  80
TRP A 119
LYS A 310
 None
 1.15A 1qu2A-2f3oA:
undetectable		 1qu2A-2f3oA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE

(Sulfurisphaera
tokodaii) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 GLU A 356
TRP A 269
LYS A 414
 None
 1.39A 1qu2A-2f7lA:
undetectable		 1qu2A-2f7lA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2frv PERIPLASMIC
HYDROGENASE

(Desulfovibrio
gigas) 		no annotation 3 GLU L 365
TRP L 304
LYS L  31
 None
 1.22A 1qu2A-2frvL:
2.4		 1qu2A-2frvL:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gq3 MALATE SYNTHASE G

(Mycobacterium
tuberculosis) 		PF01274
(Malate_synthase) 		3 GLU A 597
TRP A 647
LYS A 513
 None
 1.06A 1qu2A-2gq3A:
undetectable		 1qu2A-2gq3A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k2o MYOFERLIN

(Homo sapiens) 		no annotation 3 GLU A 994
TRP A1008
LYS A 918
 None
 1.29A 1qu2A-2k2oA:
undetectable		 1qu2A-2k2oA:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qa1 POLYKETIDE OXYGENASE
PGAE

(Streptomyces
sp. PGA64) 		PF01494
(FAD_binding_3) 		3 GLU A  40
TRP A 251
LYS A 140
 None
 1.32A 1qu2A-2qa1A:
undetectable		 1qu2A-2qa1A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rvn CHROMOBOX PROTEIN
HOMOLOG 5

(Mus musculus) 		PF00385
(Chromo) 		3 GLU A  52
TRP A  41
LYS A  72
 None
 1.35A 1qu2A-2rvnA:
undetectable		 1qu2A-2rvnA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT GAMMA

(Desulfovibrio
vulgaris) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
PF04358
(DsrC) 		3 GLU A 204
TRP A 366
LYS C  48
 None
 0.75A 1qu2A-2v4jA:
undetectable		 1qu2A-2v4jA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wd9 ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL

(Homo sapiens) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 GLU A 503
TRP A 568
LYS A 141
 None
 1.39A 1qu2A-2wd9A:
undetectable		 1qu2A-2wd9A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z95 GDP-D-MANNOSE
DEHYDRATASE

(Aquifex
aeolicus) 		PF16363
(GDP_Man_Dehyd) 		3 GLU A 229
TRP A 232
LYS A 336
 None
 1.37A 1qu2A-2z95A:
1.9		 1qu2A-2z95A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a3c MALTOSE-BINDING
PERIPLASMIC PROTEIN,
LINKER,
MITOCHONDRIAL
INTERMEMBRANE SPACE
IMPORT AND ASSEMBLY
PROTEIN 40

(Escherichia
coli;
Saccharomyces
cerevisiae;
synthetic
construct) 		PF06747
(CHCH)
PF13416
(SBP_bac_8) 		3 GLU A 111
TRP A 230
LYS A 273
 MAL  A 466 (-3.1A)
MAL  A 466 (-3.7A)
None
 1.43A 1qu2A-3a3cA:
undetectable		 1qu2A-3a3cA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aoe GLUTAMATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		3 GLU A 161
TRP A 164
LYS A 102
 None
 1.26A 1qu2A-3aoeA:
undetectable		 1qu2A-3aoeA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bql ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF03011
(PFEMP)
PF05424
(Duffy_binding) 		3 GLU A1456
TRP A1249
LYS A1422
 None
 1.33A 1qu2A-3bqlA:
undetectable		 1qu2A-3bqlA:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cf4 ACETYL-COA
DECARBOXYLASE/SYNTHA
SE ALPHA SUBUNIT
ACETYL-COA
DECARBOXYLASE/SYNTHA
SE EPSILON SUBUNIT

(Methanosarcina
barkeri) 		PF02552
(CO_dh)
PF03063
(Prismane) 		3 GLU A 771
TRP A 746
LYS G  59
 None
 1.41A 1qu2A-3cf4A:
undetectable		 1qu2A-3cf4A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f2z UNCHARACTERIZED
PROTEIN BF3579

(Bacteroides
fragilis) 		PF00754
(F5_F8_type_C) 		3 GLU A 312
TRP A 335
LYS A 293
 None
 1.29A 1qu2A-3f2zA:
undetectable		 1qu2A-3f2zA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h3l PUTATIVE SUGAR
HYDROLASE

(Parabacteroides
distasonis) 		PF06439
(DUF1080) 		3 GLU A 111
TRP A  52
LYS A  86
 None
 1.40A 1qu2A-3h3lA:
undetectable		 1qu2A-3h3lA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j82 C-TYPE LECTIN DOMAIN
FAMILY 9 MEMBER A

(Mus musculus) 		PF00059
(Lectin_C) 		3 GLU A 212
TRP A 158
LYS A 134
 None
 0.85A 1qu2A-3j82A:
undetectable		 1qu2A-3j82A:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4z GLYCOSIDE HYDROLASE
FAMILY 9

(Ruminiclostridium
thermocellum) 		PF02018
(CBM_4_9)
PF02927
(CelD_N) 		3 GLU A 112
TRP A 118
LYS A 177
 XGP  A 295 ( 4.8A)
None
None
 1.02A 1qu2A-3k4zA:
undetectable		 1qu2A-3k4zA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kf6 PROTEIN STN1

(Schizosaccharomyces
pombe) 		PF10451
(Stn1) 		3 GLU A 132
TRP A 136
LYS A  65
 None
 1.42A 1qu2A-3kf6A:
undetectable		 1qu2A-3kf6A:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l2j FUSION PROTEIN OF
MALTOSE-BINDING
PERIPLASMIC PROTEIN
AND PARATHYROID
HORMONE/PARATHYROID
HORMONE-RELATED
PEPTIDE RECEPTOR

(Escherichia
coli;
Homo sapiens) 		PF02793
(HRM)
PF13416
(SBP_bac_8) 		3 GLU A-233
TRP A-114
LYS A -71
 MAL  A 194 (-2.9A)
MAL  A 194 ( 4.6A)
None
 1.20A 1qu2A-3l2jA:
undetectable		 1qu2A-3l2jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lm3 UNCHARACTERIZED
PROTEIN

(Parabacteroides
distasonis) 		PF12979
(DUF3863)
PF12980
(DUF3864) 		3 GLU A 294
TRP A 342
LYS A 129
 None
 1.34A 1qu2A-3lm3A:
undetectable		 1qu2A-3lm3A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o98 BIFUNCTIONAL
GLUTATHIONYLSPERMIDI
NE
SYNTHETASE/AMIDASE

(Escherichia
coli) 		PF03738
(GSP_synth)
PF05257
(CHAP) 		3 GLU A  83
TRP A  82
LYS A 374
 None
 1.40A 1qu2A-3o98A:
undetectable		 1qu2A-3o98A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3or2 SULFITE REDCUTASE
SUBUNIT ALPHA
SULFITE REDCUTASE
SUBUNIT GAMA

(Desulfovibrio
gigas) 		PF01077
(NIR_SIR)
PF04358
(DsrC) 		3 GLU A 204
TRP A 366
LYS C  48
 None
 0.89A 1qu2A-3or2A:
undetectable		 1qu2A-3or2A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p6b CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Ruminiclostridium
thermocellum) 		PF02018
(CBM_4_9) 		3 GLU A 132
TRP A 138
LYS A 197
 None
 1.05A 1qu2A-3p6bA:
undetectable		 1qu2A-3p6bA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rh9 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
(NAD(P)(+))

(Marinobacter
hydrocarbonoclasticus) 		PF00171
(Aldedh) 		3 GLU A  87
TRP A 101
LYS A 120
 None
 1.41A 1qu2A-3rh9A:
undetectable		 1qu2A-3rh9A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sbg PRE-MRNA-SPLICING
FACTOR 8

(Saccharomyces
cerevisiae) 		PF08084
(PROCT)
PF12134
(PRP8_domainIV) 		3 GLU A2052
TRP A2048
LYS A2279
 None
 1.23A 1qu2A-3sbgA:
undetectable		 1qu2A-3sbgA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3szb ALDEHYDE
DEHYDROGENASE

(Homo sapiens) 		PF00171
(Aldedh) 		3 GLU A  61
TRP A  56
LYS A 137
 None
 1.26A 1qu2A-3szbA:
undetectable		 1qu2A-3szbA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tb5 METHIONINE
AMINOPEPTIDASE

(Enterococcus
faecalis) 		PF00557
(Peptidase_M24) 		3 GLU A  41
TRP A  38
LYS A 127
 None
 1.38A 1qu2A-3tb5A:
undetectable		 1qu2A-3tb5A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/DEOXYRIBONU
CLEASE SUBUNIT B

(Bacillus
subtilis) 		PF12705
(PDDEXK_1) 		3 GLU B1147
TRP B1155
LYS B1036
 None
 1.20A 1qu2A-3u44B:
undetectable		 1qu2A-3u44B:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vd8 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
INTERFERON-INDUCIBLE
PROTEIN AIM2

(Escherichia
coli;
Homo sapiens) 		PF02758
(PYRIN)
PF13416
(SBP_bac_8) 		3 GLU A 111
TRP A 230
LYS A 273
 MTT  A1205 (-2.9A)
MTT  A1205 (-4.3A)
None
 1.29A 1qu2A-3vd8A:
undetectable		 1qu2A-3vd8A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dag FUSION GLYCOPROTEIN
F0

(Human
metapneumovirus) 		PF00523
(Fusion_gly) 		3 GLU A 431
TRP A 309
LYS A 401
 None
 1.39A 1qu2A-4dagA:
undetectable		 1qu2A-4dagA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwq TRNA-SPLICING LIGASE
RTCB

(Pyrococcus
horikoshii) 		PF01139
(RtcB) 		3 GLU A 253
TRP A 263
LYS A 413
 None
 1.12A 1qu2A-4dwqA:
undetectable		 1qu2A-4dwqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4edq MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MYOSIN-BINDI
NG PROTEIN C,
CARDIAC-TYPE
CHIMERIC PROTEIN

(Escherichia
coli;
Mus musculus) 		PF07679
(I-set)
PF13416
(SBP_bac_8) 		3 GLU A 112
TRP A 231
LYS A 274
 MLR  A 500 (-2.2A)
MLR  A 500 (-4.2A)
None
 1.20A 1qu2A-4edqA:
undetectable		 1qu2A-4edqA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eqv INVERTASE 2

(Saccharomyces
cerevisiae) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		3 GLU A 370
TRP A 343
LYS A  34
 None
 1.40A 1qu2A-4eqvA:
undetectable		 1qu2A-4eqvA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ikm MALTOSE-BINDING
PERIPLASMIC PROTEIN,
CASPASE RECRUITMENT
DOMAIN-CONTAINING
PROTEIN 8

(Escherichia
coli;
Homo sapiens) 		PF00619
(CARD)
PF13416
(SBP_bac_8) 		3 GLU A 112
TRP A 231
LYS A 274
 MAL  A 501 (-2.9A)
MAL  A 501 ( 4.6A)
None
 1.31A 1qu2A-4ikmA:
undetectable		 1qu2A-4ikmA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jen CMP N-GLYCOSIDASE

(Clostridium
botulinum) 		no annotation 3 GLU A  92
TRP A  95
LYS A 141
 None
 1.32A 1qu2A-4jenA:
undetectable		 1qu2A-4jenA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l22 PHOSPHORYLASE

(Streptococcus
mutans) 		PF00343
(Phosphorylase) 		3 GLU A 582
TRP A 420
LYS A   6
 None
 1.40A 1qu2A-4l22A:
undetectable		 1qu2A-4l22A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4my2 MALTOSE-BINDING
PERIPLASMIC PROTEIN,
NORRIN FUSION
PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF00007
(Cys_knot)
PF13416
(SBP_bac_8) 		3 GLU A 113
TRP A 232
LYS A 275
 MAL  A1201 (-3.1A)
MAL  A1201 ( 4.6A)
None
 1.20A 1qu2A-4my2A:
undetectable		 1qu2A-4my2A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nuf MALTOSE ABC
TRANSPORTER
PERIPLASMIC PROTEIN,
NUCLEAR RECEPTOR
SUBFAMILY 0 GROUP B
MEMBER 2 CHIMERIC
CONSTRUCT

(Escherichia
coli;
Mus musculus) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8) 		3 GLU A 113
TRP A 232
LYS A 275
 MAL  A1301 (-2.8A)
MAL  A1301 (-4.6A)
None
 1.34A 1qu2A-4nufA:
undetectable		 1qu2A-4nufA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6d NS1

(West Nile virus) 		PF00948
(Flavi_NS1) 		3 GLU B 270
TRP B 330
LYS B  33
 None
 1.04A 1qu2A-4o6dB:
undetectable		 1qu2A-4o6dB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1t ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF03011
(PFEMP)
PF05424
(Duffy_binding) 		3 GLU A1456
TRP A1249
LYS A1422
 None
 1.22A 1qu2A-4p1tA:
undetectable		 1qu2A-4p1tA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1t ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF03011
(PFEMP)
PF05424
(Duffy_binding) 		3 GLU A1855
TRP A1802
LYS A1523
 None
 1.30A 1qu2A-4p1tA:
undetectable		 1qu2A-4p1tA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p72 PHENYLALANINE--TRNA
LIGASE BETA SUBUNIT

(Pseudomonas
aeruginosa) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		3 GLU A 258
TRP A  11
LYS A  88
 None
 1.00A 1qu2A-4p72A:
undetectable		 1qu2A-4p72A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfy ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		3 GLU A 152
TRP A 129
LYS A 502
 BMA  A 603 ( 3.2A)
BMA  A 603 ( 4.2A)
None
 1.39A 1qu2A-4pfyA:
undetectable		 1qu2A-4pfyA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxg TYPE-2 RESTRICTION
ENZYME SAU3AI

(Staphylococcus
aureus) 		PF02976
(MutH) 		3 GLU A 152
TRP A 151
LYS A 244
 None
 0.96A 1qu2A-4pxgA:
undetectable		 1qu2A-4pxgA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN

(Escherichia
coli;
Homo sapiens) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		3 GLU A 135
TRP A 254
LYS A 297
 MAL  A 801 (-2.8A)
MAL  A 801 ( 3.6A)
None
 1.05A 1qu2A-4wrnA:
undetectable		 1qu2A-4wrnA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xa2 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MBP-PILA: C

(Acinetobacter
baumannii;
Escherichia
coli) 		PF00114
(Pilin)
PF13416
(SBP_bac_8) 		3 GLU A 111
TRP A 230
LYS A 273
 MLR  A1201 (-3.1A)
MLR  A1201 (-4.4A)
None
 1.19A 1qu2A-4xa2A:
undetectable		 1qu2A-4xa2A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG

(Escherichia
coli;
Tribolium
castaneum) 		PF00104
(Hormone_recep)
PF13416
(SBP_bac_8) 		3 GLU A 113
TRP A 232
LYS A 275
 MAL  A1401 (-3.0A)
MAL  A1401 (-4.3A)
None
 1.37A 1qu2A-4xaiA:
2.2		 1qu2A-4xaiA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yjf D-AMINO-ACID OXIDASE

(Sus scrofa) 		PF01266
(DAO) 		3 GLU B  64
TRP B  67
LYS B 116
 None
 1.25A 1qu2A-4yjfB:
undetectable		 1qu2A-4yjfB:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1
ANAPHASE-PROMOTING
COMPLEX SUBUNIT 2

(Homo sapiens) 		PF00888
(Cullin)
PF08672
(ANAPC2)
PF12859
(ANAPC1) 		3 GLU A1782
TRP A1674
LYS N 320
 None
 1.36A 1qu2A-5a31A:
3.8		 1qu2A-5a31A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1
ANAPHASE-PROMOTING
COMPLEX SUBUNIT 5

(Homo sapiens) 		PF12859
(ANAPC1)
PF12862
(ANAPC5) 		3 GLU A  91
TRP A 128
LYS O 573
 None
 1.32A 1qu2A-5a31A:
3.8		 1qu2A-5a31A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN

(Thauera
aromatica) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 GLU A 132
TRP A 161
LYS A 369
 None
 1.33A 1qu2A-5bwdA:
undetectable		 1qu2A-5bwdA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9l PLL LECTIN

(Photorhabdus
luminescens) 		PF03984
(DUF346) 		3 GLU A  88
TRP A 102
LYS A 273
 None
 1.31A 1qu2A-5c9lA:
undetectable		 1qu2A-5c9lA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9l PLL LECTIN

(Photorhabdus
luminescens) 		PF03984
(DUF346) 		3 GLU A 136
TRP A 150
LYS A 320
 None
None
PG4  A 407 ( 4.7A)
 1.41A 1qu2A-5c9lA:
undetectable		 1qu2A-5c9lA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,MALTOSE-BIND
ING PERIPLASMIC
PROTEIN,PILA FUSION
PROTEIN

(Acinetobacter
nosocomialis;
Escherichia
coli) 		PF00114
(Pilin)
PF01547
(SBP_bac_1) 		3 GLU A 111
TRP A 230
LYS A 273
 MAL  A1201 (-3.0A)
MAL  A1201 ( 4.5A)
None
 1.24A 1qu2A-5cfvA:
undetectable		 1qu2A-5cfvA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dfm MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TELOMERASE-A
SSOCIATED PROTEIN 19

(Escherichia
coli;
Tetrahymena
thermophila) 		PF13416
(SBP_bac_8) 		3 GLU A 111
TRP A 230
LYS A 273
 MAL  A 601 (-3.0A)
MAL  A 601 ( 4.9A)
None
 1.28A 1qu2A-5dfmA:
undetectable		 1qu2A-5dfmA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fav CHOLINE
TRIMETHYLAMINE-LYASE

(Desulfovibrio
alaskensis) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 GLU A 137
TRP A 176
LYS A 373
 None
 1.06A 1qu2A-5favA:
undetectable		 1qu2A-5favA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fuu HIV-1 ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		3 GLU A  91
TRP A  45
LYS A 282
 None
 1.44A 1qu2A-5fuuA:
undetectable		 1qu2A-5fuuA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzv MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		3 GLU A 478
TRP A 597
LYS A 640
 MAL  A1001 (-3.1A)
MAL  A1001 (-4.8A)
None
 1.18A 1qu2A-5hzvA:
undetectable		 1qu2A-5hzvA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ii5 MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		3 GLU A3778
TRP A3897
LYS A3940
 MAL  A4201 (-3.0A)
MAL  A4201 ( 3.3A)
None
 1.24A 1qu2A-5ii5A:
undetectable		 1qu2A-5ii5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iic MALTOSE-BINDING
PERIPLASMIC
PROTEIN,VITELLINE
ENVELOPE SPERM LYSIN
RECEPTOR

(Escherichia
coli;
Haliotis
rufescens) 		PF11386
(VERL)
PF13416
(SBP_bac_8) 		3 GLU A4080
TRP A4199
LYS A4242
 MAL  A4501 (-2.7A)
MAL  A4501 ( 3.7A)
None
 1.34A 1qu2A-5iicA:
undetectable		 1qu2A-5iicA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jon MALTOSE-BINDING
PERIPLASMIC
PROTEIN,POTASSIUM/SO
DIUM
HYPERPOLARIZATION-AC
TIVATED CYCLIC
NUCLEOTIDE-GATED
CHANNEL 2

(Escherichia
coli;
Mus musculus) 		PF00027
(cNMP_binding)
PF13416
(SBP_bac_8) 		3 GLU A-258
TRP A-139
LYS A -96
 MAL  A 701 (-2.9A)
MAL  A 701 ( 4.5A)
None
 1.24A 1qu2A-5jonA:
undetectable		 1qu2A-5jonA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxr CHROMATIN-REMODELING
COMPLEX ATPASE-LIKE
PROTEIN

(Thermothelomyces
thermophila) 		PF00176
(SNF2_N)
PF00271
(Helicase_C) 		3 GLU A 165
TRP A 588
LYS A 137
 None
 1.36A 1qu2A-5jxrA:
undetectable		 1qu2A-5jxrA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5loq PUTATIVE
HEME-DEPENDENT
PEROXIDASE LMO2113

(Listeria
monocytogenes) 		PF06778
(Chlor_dismutase) 		3 GLU A  57
TRP A  11
LYS A  67
 None
 1.41A 1qu2A-5loqA:
undetectable		 1qu2A-5loqA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msn DCC1 PROTEIN

(Saccharomyces
cerevisiae) 		PF09724
(Dcc1) 		3 GLU A 232
TRP A 250
LYS A 134
 None
 1.38A 1qu2A-5msnA:
undetectable		 1qu2A-5msnA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL

(Photorhabdus
asymbiotica) 		PF03984
(DUF346) 		3 GLU A  93
TRP A 107
LYS A 277
 None
 1.41A 1qu2A-5mxfA:
undetectable		 1qu2A-5mxfA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6v AMYLOSUCRASE

(Neisseria
polysaccharea) 		no annotation 3 GLU A 271
TRP A 194
LYS A 113
 None
1PE  A 709 ( 4.4A)
None
 1.33A 1qu2A-5n6vA:
undetectable		 1qu2A-5n6vA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oas MALATE SYNTHASE G

(Pseudomonas
aeruginosa) 		no annotation 3 GLU A 595
TRP A 645
LYS A 511
 None
 1.06A 1qu2A-5oasA:
undetectable		 1qu2A-5oasA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t8v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C) 		3 GLU A1686
TRP A1762
LYS A1622
 None
 1.30A 1qu2A-5t8vA:
1.6		 1qu2A-5t8vA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF04598
(Gasdermin)
PF13416
(SBP_bac_8) 		3 GLU A 111
TRP A 230
LYS A 273
 MAL  A1501 (-3.0A)
MAL  A1501 ( 4.6A)
None
 1.20A 1qu2A-5tj2A:
undetectable		 1qu2A-5tj2A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tqi PYRIDOXAL KINASE
PDXY

(Burkholderia
multivorans) 		PF08543
(Phos_pyr_kin) 		3 GLU A 242
TRP A 203
LYS A  -1
 None
 1.42A 1qu2A-5tqiA:
undetectable		 1qu2A-5tqiA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ttd MALTOSE-BINDING
PERIPLASMIC
PROTEIN,PILIN
ISOPEPTIDE LINKAGE
DOMAIN PROTEIN

(Escherichia
coli;
Streptococcus
pyogenes) 		PF12892
(FctA)
PF13416
(SBP_bac_8) 		3 GLU A 117
TRP A 236
LYS A 279
 MLR  A 501 (-2.8A)
MLR  A 501 ( 4.6A)
None
 1.30A 1qu2A-5ttdA:
undetectable		 1qu2A-5ttdA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
US5

(Toxoplasma
gondii) 		PF00333
(Ribosomal_S5)
PF03719
(Ribosomal_S5_C) 		3 GLU C  67
TRP C  37
LYS C 127
 None
None
U  21285 ( 3.1A)
 1.41A 1qu2A-5xxuC:
undetectable		 1qu2A-5xxuC:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yf0 -

(-) 		no annotation 3 GLU A 217
TRP A 216
LYS A 395
 None
 1.32A 1qu2A-5yf0A:
undetectable		 1qu2A-5yf0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axe MALATE SYNTHASE G

(Mycobacterium
marinum) 		PF01274
(Malate_synthase) 		3 GLU A 601
TRP A 651
LYS A 517
 None
 1.04A 1qu2A-6axeA:
undetectable		 1qu2A-6axeA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c66 CRISPR-ASSOCIATED
HELICASE, CAS3
FAMILY

(Thermobifida
fusca) 		no annotation 3 GLU G  24
TRP G  21
LYS G 411
 None
 1.29A 1qu2A-6c66G:
undetectable		 1qu2A-6c66G:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN

(Homo sapiens) 		no annotation 3 GLU A 428
TRP A 401
LYS A 481
 None
 1.42A 1qu2A-6ei1A:
1.3		 1qu2A-6ei1A:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8z ALPHA-1,2-MANNOSIDAS
E, PUTATIVE

(Bacteroides
thetaiotaomicron) 		no annotation 3 GLU A 595
TRP A 352
LYS A 295
 CA  A 801 (-2.9A)
None
None
 1.32A 1qu2A-6f8zA:
3.3		 1qu2A-6f8zA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fik POLYKETIDE SYNTHASE

(Cercospora
nicotianae) 		no annotation 3 GLU A 618
TRP A 444
LYS A 751
 None
 1.01A 1qu2A-6fikA:
undetectable		 1qu2A-6fikA:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 5
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
4, MITOCHONDRIAL

(Mus musculus) 		no annotation 3 GLU C  91
TRP V 111
LYS Q 108
 None
 1.31A 1qu2A-6g2jC:
undetectable		 1qu2A-6g2jC:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gne -

(-) 		no annotation 3 GLU A 113
TRP A 122
LYS A  52
 None
 1.09A 1qu2A-6gneA:
2.3		 1qu2A-6gneA:
undetectable