SIMILAR PATTERNS OF AMINO ACIDS FOR 1QOM_A_H4BA902_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a80 | 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE A (Corynebacteriumsp.) |
PF00248(Aldo_ket_red) | 3 | ARG A 171ILE A 255TRP A 221 | None | 0.99A | 1qomA-1a80A:undetectable | 1qomA-1a80A:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g5b | SERINE/THREONINEPROTEIN PHOSPHATASE (Escherichiavirus Lambda) |
PF00149(Metallophos) | 3 | ARG A 162ILE A 159TRP A 160 | SO4 A3001 (-3.3A)NoneNone | 0.90A | 1qomA-1g5bA:undetectable | 1qomA-1g5bA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gff | BACTERIOPHAGE G4CAPSID PROTEINS GPF,GPG, GPJ (Escherichiavirus G4) |
PF02305(Phage_F) | 3 | ARG 1 382ILE 1 168TRP 1 169 | None | 1.09A | 1qomA-1gff1:0.0 | 1qomA-1gff1:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hpl | LIPASE (Equus caballus) |
PF00151(Lipase)PF01477(PLAT) | 3 | ARG A 439ILE A 401TRP A 402 | None | 1.12A | 1qomA-1hplA:0.2 | 1qomA-1hplA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iir | GLYCOSYLTRANSFERASEGTFB (Amycolatopsisorientalis) |
PF03033(Glyco_transf_28) | 3 | ARG A 157ILE A 151TRP A 155 | None | 1.15A | 1qomA-1iirA:0.0 | 1qomA-1iirA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iiw | SLR1257 PROTEIN (Synechocystissp. PCC 6803) |
PF00497(SBP_bac_3) | 3 | ARG A 36ILE A 30TRP A 224 | None | 1.12A | 1qomA-1iiwA:0.0 | 1qomA-1iiwA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqg | CARBOXYPEPTIDASE A (Helicoverpaarmigera) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 3 | ARG A 302ILE A 100TRP A 105 | None | 1.01A | 1qomA-1jqgA:undetectable | 1qomA-1jqgA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kb0 | QUINOHEMOPROTEINALCOHOLDEHYDROGENASE (Comamonastestosteroni) |
PF13360(PQQ_2)PF13442(Cytochrome_CBB3) | 3 | ARG A 67ILE A 107TRP A 136 | HEC A 802 (-4.2A)NoneNone | 1.17A | 1qomA-1kb0A:undetectable | 1qomA-1kb0A:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ltm | 36 KDA SOLUBLE LYTICTRANSGLYCOSYLASE (Escherichiacoli) |
PF13406(SLT_2) | 3 | ARG A 167ILE A 159TRP A 165 | None | 1.19A | 1qomA-1ltmA:0.0 | 1qomA-1ltmA:19.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qw5 | NITRIC OXIDESYNTHASE, INDUCIBLE (Mus musculus) |
PF02898(NO_synthase) | 3 | ARG A 375ILE A 456TRP A 457 | H4B A 901 (-3.4A)H4B A 901 (-4.7A)H4B A 901 ( 3.7A) | 0.47A | 1qomA-1qw5A:60.1 | 1qomA-1qw5A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v10 | LACCASE (Rigidoporusmicroporus) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 3 | ARG A 121ILE A 454TRP A 456 | None CU A1503 (-3.4A)None | 1.06A | 1qomA-1v10A:undetectable | 1qomA-1v10A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wlt | 176AA LONGHYPOTHETICALDTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE (Sulfurisphaeratokodaii) |
PF00908(dTDP_sugar_isom) | 3 | ARG A 40ILE A 13TRP A 111 | None | 0.98A | 1qomA-1wltA:undetectable | 1qomA-1wltA:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wms | RAS-RELATED PROTEINRAB-9A (Homo sapiens) |
PF00071(Ras) | 3 | ARG A 78ILE A 11TRP A 61 | None | 1.15A | 1qomA-1wmsA:undetectable | 1qomA-1wmsA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z06 | RAS-RELATED PROTEINRAB-33B (Mus musculus) |
PF00071(Ras) | 3 | ARG A 105ILE A 37TRP A 87 | None | 1.04A | 1qomA-1z06A:undetectable | 1qomA-1z06A:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a46 | GFP-LIKE FLUORESCENTCHROMOPROTEINAMFP486 (Anemonia majano) |
PF01353(GFP) | 3 | ARG A 72ILE A 113TRP A 111 | CR7 A 68 ( 4.4A)NoneCR7 A 68 ( 4.1A) | 0.93A | 1qomA-2a46A:undetectable | 1qomA-2a46A:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ayu | NUCLEOSOME ASSEMBLYPROTEIN (Saccharomycescerevisiae) |
PF00956(NAP) | 3 | ARG A 355ILE A 131TRP A 132 | None | 0.90A | 1qomA-2ayuA:undetectable | 1qomA-2ayuA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b24 | NAPHTHALENEDIOXYGENASE LARGESUBUNIT (Rhodococcus sp.NCIMB 12038) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 3 | ARG A 324ILE A 199TRP A 197 | None | 1.03A | 1qomA-2b24A:undetectable | 1qomA-2b24A:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cw3 | IRON SUPEROXIDEDISMUTASE (Perkinsusmarinus) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 3 | ARG A 101ILE A 163TRP A 137 | None | 1.18A | 1qomA-2cw3A:undetectable | 1qomA-2cw3A:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fa8 | HYPOTHETICAL PROTEINATU0228 (Agrobacteriumfabrum) |
PF10262(Rdx) | 3 | ARG A 64ILE A 52TRP A 60 | None | 1.13A | 1qomA-2fa8A:undetectable | 1qomA-2fa8A:14.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fkn | UROCANATE HYDRATASE (Bacillussubtilis) |
PF01175(Urocanase)PF17391(Urocanase_N)PF17392(Urocanase_C) | 3 | ARG A 414ILE A 406TRP A 408 | None | 0.98A | 1qomA-2fknA:undetectable | 1qomA-2fknA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hen | EPHRIN TYPE-BRECEPTOR 2 (Mus musculus) |
PF07714(Pkinase_Tyr) | 3 | ARG A 833ILE A 822TRP A 800 | None | 1.14A | 1qomA-2henA:undetectable | 1qomA-2henA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inc | TOLUENE, O-XYLENEMONOOXYGENASEOXYGENASE SUBUNIT (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox)PF04945(YHS) | 3 | ARG A 116ILE B 145TRP B 57 | None | 1.21A | 1qomA-2incA:undetectable | 1qomA-2incA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jaq | DEOXYGUANOSINEKINASE (Mycoplasmamycoides) |
PF01712(dNK) | 3 | ARG A 145ILE A 139TRP A 158 | DCP A1202 (-2.8A)NoneNone | 1.02A | 1qomA-2jaqA:undetectable | 1qomA-2jaqA:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ljr | GLUTATHIONES-TRANSFERASE (Homo sapiens) |
PF00043(GST_C)PF02798(GST_N) | 3 | ARG A 107ILE A 112TRP A 115 | None | 1.13A | 1qomA-2ljrA:undetectable | 1qomA-2ljrA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nba | PREPILIN-TYPECLEAVAGE/METHYLATIONN-TERMINAL DOMAINPROTEIN (Neisseriasubflava) |
PF16732(ComP_DUS) | 3 | ARG A 113ILE A 64TRP A 42 | None | 1.12A | 1qomA-2nbaA:undetectable | 1qomA-2nbaA:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pes | URICASE (Aspergillusflavus) |
PF01014(Uricase) | 3 | ARG A 128ILE A 142TRP A 188 | None | 0.87A | 1qomA-2pesA:undetectable | 1qomA-2pesA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qi2 | CELL DIVISIONPROTEIN PELOTARELATED PROTEIN (Thermoplasmaacidophilum) |
PF03463(eRF1_1)PF03465(eRF1_3) | 3 | ARG A 293ILE A 70TRP A 24 | None | 1.04A | 1qomA-2qi2A:undetectable | 1qomA-2qi2A:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v7g | UROCANATE HYDRATASE (Pseudomonasputida) |
PF01175(Urocanase)PF17391(Urocanase_N)PF17392(Urocanase_C) | 3 | ARG A 418ILE A 410TRP A 412 | None | 0.94A | 1qomA-2v7gA:undetectable | 1qomA-2v7gA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2r | NUCLEOSOME ASSEMBLYPROTEIN (Saccharomycescerevisiae) |
PF00956(NAP) | 3 | ARG A 355ILE A 131TRP A 132 | None | 1.04A | 1qomA-2z2rA:undetectable | 1qomA-2z2rA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cji | POLYPROTEIN (Senecavirus A) |
no annotation | 3 | ARG A 169ILE A 217TRP A 140 | None | 1.16A | 1qomA-3cjiA:undetectable | 1qomA-3cjiA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dfr | DIHYDROFOLATEREDUCTASE (Lactobacilluscasei) |
PF00186(DHFR_1) | 3 | ARG A 117ILE A 13TRP A 5 | NoneNDP A 163 (-3.8A)None | 0.97A | 1qomA-3dfrA:undetectable | 1qomA-3dfrA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dko | EPHRIN TYPE-ARECEPTOR 7 (Homo sapiens) |
PF07714(Pkinase_Tyr)PF14575(EphA2_TM) | 3 | ARG A 835ILE A 824TRP A 802 | None | 1.02A | 1qomA-3dkoA:undetectable | 1qomA-3dkoA:21.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3e7g | NITRIC OXIDESYNTHASE, INDUCIBLE (Homo sapiens) |
PF02898(NO_synthase) | 3 | ARG A 381ILE A 462TRP A 463 | H4B A 902 (-3.9A)H4B A 902 (-4.9A)H4B A 902 ( 3.6A) | 0.39A | 1qomA-3e7gA:58.3 | 1qomA-3e7gA:87.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9k | INTEGRASE (Humanimmunodeficiencyvirus 2) |
PF00665(rve)PF02022(Integrase_Zn) | 3 | ARG A 107ILE A 110TRP A 61 | None | 0.95A | 1qomA-3f9kA:undetectable | 1qomA-3f9kA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6s | SUBTILISIN-LIKEPROTEASE (Solanumlycopersicum) |
PF00082(Peptidase_S8) | 3 | ARG A 165ILE A 162TRP A 166 | None | 1.12A | 1qomA-3i6sA:undetectable | 1qomA-3i6sA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iy7 | FRAGMENT FROMNEUTRALIZINGANTIBODY F (HEAVYCHAIN) (Rattusnorvegicus) |
PF07686(V-set) | 3 | ARG B 164ILE B 148TRP B 147 | None | 1.09A | 1qomA-3iy7B:undetectable | 1qomA-3iy7B:13.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j81 | US2 (Kluyveromyceslactis) |
PF00318(Ribosomal_S2) | 3 | ARG A 183ILE A 57TRP A 54 | None | 1.20A | 1qomA-3j81A:undetectable | 1qomA-3j81A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR SPP42 (Schizosaccharomycespombe) |
PF08082(PRO8NT)PF08083(PROCN)PF10596(U6-snRNA_bdg)PF10597(U5_2-snRNA_bdg)PF10598(RRM_4)PF12134(PRP8_domainIV) | 3 | ARG A1055ILE A1115TRP A1064 | None | 1.18A | 1qomA-3jb9A:undetectable | 1qomA-3jb9A:10.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jq3 | LOMBRICINE KINASE (Urechis caupo) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 3 | ARG A 117ILE A 214TRP A 215 | ADP A 400 (-2.6A)NoneNone | 0.91A | 1qomA-3jq3A:undetectable | 1qomA-3jq3A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k30 | HISTAMINEDEHYDROGENASE (Pimelobactersimplex) |
PF00724(Oxidored_FMN)PF07992(Pyr_redox_2) | 3 | ARG A 429ILE A 349TRP A 442 | NoneSF4 A 801 (-4.1A)None | 1.19A | 1qomA-3k30A:undetectable | 1qomA-3k30A:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwd | 6-PHOSPHOGLUCONOLACTONASE (Chromohalobactersalexigens) |
PF01182(Glucosamine_iso) | 3 | ARG A 9ILE A 188TRP A 223 | None | 0.90A | 1qomA-3lwdA:undetectable | 1qomA-3lwdA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m6m | RPFF PROTEIN (Xanthomonascampestris) |
PF00378(ECH_1) | 3 | ARG A 24ILE A 19TRP A 28 | None | 1.13A | 1qomA-3m6mA:undetectable | 1qomA-3m6mA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opy | 6-PHOSPHOFRUCTO-1-KINASE ALPHA-SUBUNIT (Komagataellapastoris) |
PF00365(PFK) | 3 | ARG A 230ILE A 237TRP A 265 | SO4 A 996 (-4.3A)NoneNone | 1.09A | 1qomA-3opyA:undetectable | 1qomA-3opyA:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pqs | TRANSFERRIN-BINDINGPROTEIN (Actinobacilluspleuropneumoniae) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 3 | ARG A 221ILE A 193TRP A 152 | GOL A3968 (-3.5A)NoneNone | 1.21A | 1qomA-3pqsA:undetectable | 1qomA-3pqsA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s95 | LIM DOMAIN KINASE 1 (Homo sapiens) |
PF07714(Pkinase_Tyr) | 3 | ARG A 422ILE A 537TRP A 515 | TRS A 640 (-3.9A)NoneNone | 1.12A | 1qomA-3s95A:undetectable | 1qomA-3s95A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s9v | ABIETADIENESYNTHASE,CHLOROPLASTIC (Abies grandis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | ARG A 749ILE A 685TRP A 689 | None | 1.05A | 1qomA-3s9vA:undetectable | 1qomA-3s9vA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6w | LACCASE (Steccherinumochraceum) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 3 | ARG A 122ILE A 455TRP A 457 | None CU A 501 (-3.8A)None | 0.94A | 1qomA-3t6wA:undetectable | 1qomA-3t6wA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tw5 | TRANSGLUTAMINASEELICITOR (Phytophthorasojae) |
PF16683(TGase_elicitor) | 3 | ARG A 438ILE A 442TRP A 441 | None | 1.07A | 1qomA-3tw5A:undetectable | 1qomA-3tw5A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w36 | NAPH1 (Streptomycessp. CNQ525) |
no annotation | 3 | ARG A 385ILE A 406TRP A 411 | None | 0.71A | 1qomA-3w36A:undetectable | 1qomA-3w36A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zhc | PHYTASE (Citrobacterbraakii) |
PF00328(His_Phos_2) | 3 | ARG A 158ILE A 152TRP A 210 | None | 1.03A | 1qomA-3zhcA:undetectable | 1qomA-3zhcA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ano | ESSB (Geobacillusthermodenitrificans) |
PF10140(YukC) | 3 | ARG A 102ILE A 104TRP A 136 | None | 0.91A | 1qomA-4anoA:undetectable | 1qomA-4anoA:18.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxs | VENOM PROTHROMBINACTIVATORPSEUTARIN-CNON-CATALYTICSUBUNIT (Pseudonajatextilis) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 3 | ARG V 926ILE V 961TRP V 939 | None | 0.95A | 1qomA-4bxsV:undetectable | 1qomA-4bxsV:15.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4czx | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN2PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN3 (Neurosporacrassa) |
no annotation | 3 | ARG A 104ILE A 64TRP B 566 | PO4 A 401 (-4.0A)NoneNone | 0.95A | 1qomA-4czxA:undetectable | 1qomA-4czxA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ddw | REVERSE GYRASE (Thermotogamaritima) |
PF00270(DEAD)PF01131(Topoisom_bac)PF01751(Toprim) | 3 | ARG A 931ILE A 859TRP A 885 | None | 1.07A | 1qomA-4ddwA:undetectable | 1qomA-4ddwA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g0j | NON-STRUCTURALPROTEIN 2 (Rotavirus A) |
PF02509(Rota_NS35) | 3 | ARG A 227ILE A 265TRP A 269 | None | 0.90A | 1qomA-4g0jA:undetectable | 1qomA-4g0jA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iig | BETA-GLUCOSIDASE 1 (Aspergillusaculeatus) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 3 | ARG A 521ILE A 548TRP A 570 | None | 1.20A | 1qomA-4iigA:undetectable | 1qomA-4iigA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kh8 | HYPOTHETICAL PROTEIN (Enterococcusfaecalis) |
PF16103(DUF4822) | 3 | ARG A 190ILE A 89TRP A 65 | None | 1.20A | 1qomA-4kh8A:undetectable | 1qomA-4kh8A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mwf | FAB AR3C HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 3 | ARG A 94ILE A 69TRP A 36 | None | 1.14A | 1qomA-4mwfA:undetectable | 1qomA-4mwfA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4okj | 3'-5'EXORIBONUCLEASERV2179C/MT2234.1 (Mycobacteriumtuberculosis) |
PF16473(DUF5051) | 3 | ARG A 135ILE A 156TRP A 124 | None | 1.02A | 1qomA-4okjA:undetectable | 1qomA-4okjA:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p2k | EPHRIN TYPE-ARECEPTOR 2 (Homo sapiens) |
PF07714(Pkinase_Tyr)PF14575(EphA2_TM) | 3 | ARG A 816ILE A 805TRP A 783 | None | 1.17A | 1qomA-4p2kA:undetectable | 1qomA-4p2kA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tsk | KETOL-ACIDREDUCTOISOMERASE (Alicyclobacillusacidocaldarius) |
PF01450(IlvC)PF07991(IlvN) | 3 | ARG A 84ILE A 291TRP A 290 | None | 1.10A | 1qomA-4tskA:undetectable | 1qomA-4tskA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uri | CHITINASE-RELATEDAGGLUTININ (Robiniapseudoacacia) |
PF00704(Glyco_hydro_18) | 3 | ARG A 135ILE A 100TRP A 134 | NA A 502 ( 4.4A)NoneNone | 1.20A | 1qomA-4uriA:undetectable | 1qomA-4uriA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zb3 | NUDIX HYDROLASE 7 (Arabidopsisthaliana) |
PF00293(NUDIX) | 3 | ARG A 74ILE A 53TRP A 54 | None | 1.05A | 1qomA-4zb3A:undetectable | 1qomA-4zb3A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zkt | BOTULINUM NEUROTOXINTYPE E,NONTOXIC-NONHEMAGGLUTININ COMPONENT,NTNH (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07953(Toxin_R_bind_N)PF08470(NTNH_C) | 3 | ARG B 24ILE B 168TRP B 169 | None | 1.19A | 1qomA-4zktB:undetectable | 1qomA-4zktB:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxi | TYROCIDINESYNTHETASE 3 (Acinetobacterbaumannii) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 3 | ARG A1164ILE A1161TRP A1134 | None | 0.88A | 1qomA-4zxiA:undetectable | 1qomA-4zxiA:15.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxi | TYROCIDINESYNTHETASE 3 (Acinetobacterbaumannii) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 3 | ARG A1164ILE A1298TRP A1134 | None | 0.99A | 1qomA-4zxiA:undetectable | 1qomA-4zxiA:15.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a01 | O-GLYCOSYLTRANSFERASE (Drosophilamelanogaster) |
PF13374(TPR_10)PF13414(TPR_11)PF13844(Glyco_transf_41) | 3 | ARG A 852ILE A 921TRP A 894 | None | 1.16A | 1qomA-5a01A:undetectable | 1qomA-5a01A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5an9 | 60S RIBOSOMALPROTEIN L24 (Dictyosteliumdiscoideum) |
PF01246(Ribosomal_L24e) | 3 | ARG G 56ILE G 49TRP G 51 | None | 1.04A | 1qomA-5an9G:undetectable | 1qomA-5an9G:9.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c2v | HYDRAZINE SYNTHASEALPHA SUBUNIT (CandidatusKueneniastuttgartiensis) |
no annotation | 3 | ARG A 227ILE A 163TRP A 423 | None | 1.09A | 1qomA-5c2vA:undetectable | 1qomA-5c2vA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cs4 | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF08326(ACC_central) | 3 | ARG A1173ILE A1115TRP A1131 | None | 1.04A | 1qomA-5cs4A:1.3 | 1qomA-5cs4A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csa | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF00364(Biotin_lipoyl)PF08326(ACC_central) | 3 | ARG A1173ILE A1115TRP A1131 | None | 1.20A | 1qomA-5csaA:1.7 | 1qomA-5csaA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ehf | LACCASE (Antrodiellafaginea) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 3 | ARG A 121ILE A 453TRP A 455 | None CU A 510 (-3.7A)None | 0.98A | 1qomA-5ehfA:undetectable | 1qomA-5ehfA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f2v | GTPPYROPHOSPHOKINASEYJBM (Bacillussubtilis) |
no annotation | 3 | ARG V 143ILE V 153TRP V 150 | APC V 301 ( 4.9A)NoneNone | 0.93A | 1qomA-5f2vV:undetectable | 1qomA-5f2vV:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5flz | TUBULIN GAMMA CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 3 | ARG C 114ILE C 119TRP C 93 | None | 1.09A | 1qomA-5flzC:undetectable | 1qomA-5flzC:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fn4 | GAMMA-SECRETASESUBUNIT APH-1A (Homo sapiens) |
PF06105(Aph-1) | 3 | ARG C 186ILE C 230TRP C 227 | None | 1.15A | 1qomA-5fn4C:undetectable | 1qomA-5fn4C:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fsy | MACRODOMAIN (Trypanosomabrucei) |
PF01661(Macro) | 3 | ARG A 169ILE A 57TRP A 76 | None | 1.04A | 1qomA-5fsyA:undetectable | 1qomA-5fsyA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzu | CHITINASE (Paenibacillussp. FPU-7) |
PF00704(Glyco_hydro_18) | 3 | ARG A1190ILE A1187TRP A1176 | None | 1.01A | 1qomA-5gzuA:undetectable | 1qomA-5gzuA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1k | GEM-ASSOCIATEDPROTEIN 5 (Homo sapiens) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 3 | ARG A 260ILE A 253TRP A 254 | None | 1.11A | 1qomA-5h1kA:undetectable | 1qomA-5h1kA:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibv | CAPSID POLYPROTEINVP90 (Mamastrovirus 1) |
PF03115(Astro_capsid_N) | 3 | ARG A 179ILE A 102TRP A 350 | None | 1.18A | 1qomA-5ibvA:undetectable | 1qomA-5ibvA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ja1 | ENTEROBACTINSYNTHASE COMPONENT F (Escherichiacoli) |
PF00501(AMP-binding)PF00550(PP-binding)PF00668(Condensation)PF00975(Thioesterase)PF13193(AMP-binding_C) | 3 | ARG A 623ILE A 659TRP A 656 | None | 1.19A | 1qomA-5ja1A:undetectable | 1qomA-5ja1A:15.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3z | POLYKETIDEKETOREDUCTASE SIMC7 (Streptomycesantibioticus) |
PF13460(NAD_binding_10) | 3 | ARG A 130ILE A 119TRP A 126 | None | 1.17A | 1qomA-5l3zA:undetectable | 1qomA-5l3zA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l46 | DIMETHYLGLYCINEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF01266(DAO)PF01571(GCV_T)PF08669(GCV_T_C)PF16350(FAO_M) | 3 | ARG A 605ILE A 607TRP A 606 | None | 1.19A | 1qomA-5l46A:undetectable | 1qomA-5l46A:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mew | LACCASE 2 (Steccherinummurashkinskyi) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 3 | ARG A 122ILE A 455TRP A 457 | None CU A 504 (-3.8A)None | 0.99A | 1qomA-5mewA:undetectable | 1qomA-5mewA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n77 | MAGNESIUM TRANSPORTPROTEIN CORA (Escherichiacoli) |
PF01544(CorA) | 3 | ARG A 14ILE A 29TRP A 28 | None | 1.05A | 1qomA-5n77A:undetectable | 1qomA-5n77A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5npr | UDP-N-ACETYLGLUCOSAMINE--PEPTIDEN-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDASUBUNIT (Homo sapiens) |
no annotation | 3 | ARG A 822ILE A 891TRP A 864 | None | 1.15A | 1qomA-5nprA:undetectable | 1qomA-5nprA:10.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojr | - (-) |
no annotation | 3 | ARG A 82ILE A 64TRP A 70 | None | 1.08A | 1qomA-5ojrA:undetectable | 1qomA-5ojrA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqj | RNA POLYMERASE IITRANSCRIPTION FACTORB SUBUNIT 1 (Saccharomycescerevisiae) |
no annotation | 3 | ARG 1 30ILE 1 16TRP 1 29 | None | 0.91A | 1qomA-5oqj1:undetectable | 1qomA-5oqj1:11.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqm | GENERALTRANSCRIPTION ANDDNA REPAIR FACTORIIH SUBUNIT TFB1 (Saccharomycescerevisiae) |
no annotation | 3 | ARG 1 30ILE 1 16TRP 1 29 | None | 0.90A | 1qomA-5oqm1:undetectable | 1qomA-5oqm1:11.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t89 | VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 1 (Homo sapiens) |
PF00047(ig)PF07679(I-set)PF13927(Ig_3) | 3 | ARG X 546ILE X 464TRP X 466 | None | 1.17A | 1qomA-5t89X:undetectable | 1qomA-5t89X:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tey | N6-ADENOSINE-METHYLTRANSFERASE 70 KDASUBUNIT (Homo sapiens) |
PF05063(MT-A70) | 3 | ARG A 508ILE A 503TRP A 457 | None | 0.83A | 1qomA-5teyA:undetectable | 1qomA-5teyA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u6o | POTASSIUM/SODIUMHYPERPOLARIZATION-ACTIVATED CYCLICNUCLEOTIDE-GATEDCHANNEL 1 (Homo sapiens) |
PF00027(cNMP_binding)PF00520(Ion_trans)PF08412(Ion_trans_N) | 3 | ARG A 267ILE A 176TRP A 175 | None | 1.20A | 1qomA-5u6oA:undetectable | 1qomA-5u6oA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uhe | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA' (Mycobacteriumtuberculosis) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 3 | ARG D 113ILE D 104TRP D 105 | None | 0.98A | 1qomA-5uheD:undetectable | 1qomA-5uheD:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vk2 | PRE-GLYCOPROTEINPOLYPROTEIN GPCOMPLEX (Lassamammarenavirus) |
PF00798(Arena_glycoprot) | 3 | ARG A 193ILE A 239TRP A 196 | None | 1.10A | 1qomA-5vk2A:undetectable | 1qomA-5vk2A:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ygh | CAPSID PROTEIN (Zika virus) |
no annotation | 3 | ARG A 55ILE A 66TRP A 69 | None | 1.03A | 1qomA-5yghA:undetectable | 1qomA-5yghA:12.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yqw | PEPTIDE ABCTRANSPORTER,PERIPLASMICPEPTIDE-BINDINGPROTEIN (Vibrio harveyi) |
no annotation | 3 | ARG A 509ILE A 512TRP A 513 | NoneNoneCBS A 604 (-3.8A) | 1.15A | 1qomA-5yqwA:undetectable | 1qomA-5yqwA:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z5d | BETA-XYLOSIDASE (Geobacillusthermoleovorans) |
no annotation | 3 | ARG A 142ILE A 114TRP A 117 | None | 1.16A | 1qomA-5z5dA:undetectable | 1qomA-5z5dA:8.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6byk | 14-3-3 PROTEINBETA/ALPHA (Homo sapiens) |
no annotation | 3 | ARG A 58ILE A 88TRP A 61 | None | 1.13A | 1qomA-6bykA:undetectable | 1qomA-6bykA:10.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c7v | - (-) |
no annotation | 3 | ARG A 202ILE A 11TRP A 50 | None | 1.19A | 1qomA-6c7vA:undetectable | 1qomA-6c7vA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfz | ASK1DAD4 (Chaetomiumthermophilum) |
no annotation | 3 | ARG A 59ILE E 44TRP A 62 | None | 1.00A | 1qomA-6cfzA:undetectable | 1qomA-6cfzA:10.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ei1 | ZINC FINGER WITHUFM1-SPECIFICPEPTIDASE DOMAINPROTEIN (Homo sapiens) |
no annotation | 3 | ARG A 338ILE A 498TRP A 341 | None | 1.01A | 1qomA-6ei1A:undetectable | 1qomA-6ei1A:11.43 |