SIMILAR PATTERNS OF AMINO ACIDS FOR 1QHS_A_CLMA999_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyt CYTOSOL
AMINOPEPTIDASE

(Escherichia
coli) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		5 SER A   9
VAL A  20
ILE A  73
ILE A  43
GLN A  34
 None
 1.02A 1qhsA-1gytA:
undetectable		 1qhsA-1gytA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg8 ENDOPOLYGALACTURONAS
E

(Fusarium
verticillioides) 		PF00295
(Glyco_hydro_28) 		5 ILE A  88
ILE A 105
PHE A  71
ILE A 146
LEU A 167
 None
 0.92A 1qhsA-1hg8A:
undetectable		 1qhsA-1hg8A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ig0 THIAMIN
PYROPHOSPHOKINASE

(Saccharomyces
cerevisiae) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		5 ILE A 117
ILE A 147
PHE A 143
VAL A  66
LEU A  64
 None
 1.00A 1qhsA-1ig0A:
undetectable		 1qhsA-1ig0A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lxy ARGININE DEIMINASE

(Mycoplasma
arginini) 		PF02274
(Amidinotransf) 		5 SER A 187
ILE A  11
PHE A   8
VAL A 190
LEU A  78
 None
 0.94A 1qhsA-1lxyA:
undetectable		 1qhsA-1lxyA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mw9 DNA TOPOISOMERASE I

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		6 VAL X   8
ILE X 142
ILE X 147
PHE X 139
VAL X  27
LEU X  21
 None
 1.22A 1qhsA-1mw9X:
undetectable		 1qhsA-1mw9X:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nhc POLYGALACTURONASE I

(Aspergillus
niger) 		PF00295
(Glyco_hydro_28) 		5 VAL A 247
ILE A 249
ILE A 210
ILE A 190
VAL A 244
 None
 0.95A 1qhsA-1nhcA:
undetectable		 1qhsA-1nhcA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ny5 TRANSCRIPTIONAL
REGULATOR (NTRC
FAMILY)

(Aquifex
aeolicus) 		PF00072
(Response_reg)
PF00158
(Sigma54_activat) 		5 VAL A 362
ILE A 363
ILE A 375
PHE A 339
VAL A 384
 None
 0.94A 1qhsA-1ny5A:
3.8		 1qhsA-1ny5A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oal SUPEROXIDE DISMUTASE

(Photobacterium
leiognathi) 		PF00080
(Sod_Cu) 		6 ILE A  19
ILE A 122
PHE A  44
ILE A  46
VAL A  28
LEU A 112
 None
 1.43A 1qhsA-1oalA:
undetectable		 1qhsA-1oalA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1odu PUTATIVE
ALPHA-L-FUCOSIDASE

(Thermotoga
maritima) 		PF01120
(Alpha_L_fucos) 		5 ILE A 398
ILE A 374
PHE A 376
PHE A 387
VAL A 408
 None
 0.97A 1qhsA-1oduA:
undetectable		 1qhsA-1oduA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ps9 2,4-DIENOYL-COA
REDUCTASE

(Escherichia
coli) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		5 VAL A 621
ILE A 499
ILE A 505
VAL A 486
LEU A 487
 None
None
NAP  A 703 (-3.4A)
None
FAD  A 701 (-4.7A)
 0.96A 1qhsA-1ps9A:
2.2		 1qhsA-1ps9A:
14.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qhx PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)

(Streptomyces
venezuelae) 		PF07931
(CPT) 		11 SER A  12
VAL A  36
ILE A  40
ILE A  54
PHE A  56
ILE A  64
PHE A  68
VAL A  94
LEU A  96
MET A 140
GLN A 144
 ATP  A 501 (-2.6A)
None
None
None
None
None
None
None
None
None
None
 0.59A 1qhsA-1qhxA:
33.8		 1qhsA-1qhxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qhx PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)

(Streptomyces
venezuelae) 		PF07931
(CPT) 		11 VAL A  36
ILE A  40
ILE A  54
PHE A  56
ILE A  64
PHE A  68
VAL A  94
LEU A  96
ARG A 136
MET A 140
GLN A 144
 None
None
None
None
None
None
None
None
ATP  A 501 (-1.8A)
None
None
 0.81A 1qhsA-1qhxA:
33.8		 1qhsA-1qhxA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1spp MAJOR SEMINAL PLASMA
GLYCOPROTEIN PSP-II

(Sus scrofa) 		PF00431
(CUB) 		5 SER B  83
VAL B  60
ILE B  90
ILE B 105
ILE B  46
 None
 0.77A 1qhsA-1sppB:
undetectable		 1qhsA-1sppB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tye INTEGRIN BETA-3

(Homo sapiens) 		PF00362
(Integrin_beta)
PF17205
(PSI_integrin) 		5 VAL B 359
ILE B 416
ILE B 399
PHE B 100
PHE B 370
 None
 0.89A 1qhsA-1tyeB:
2.2		 1qhsA-1tyeB:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vft ALANINE RACEMASE

(Streptomyces
lavendulae) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		5 VAL A 303
ILE A 338
ILE A 293
ILE A 316
VAL A 323
 None
 0.98A 1qhsA-1vftA:
undetectable		 1qhsA-1vftA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhe AMINOPEPTIDASE/GLUCA
NASE HOMOLOG

(Bacillus
subtilis) 		PF05343
(Peptidase_M42) 		5 VAL A 346
ILE A 347
ILE A  63
VAL A 279
LEU A 275
 None
 0.87A 1qhsA-1vheA:
2.3		 1qhsA-1vheA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wlf PEROXISOME
BIOGENESIS FACTOR 1

(Mus musculus) 		PF09262
(PEX-1N)
PF09263
(PEX-2N) 		6 VAL A 108
ILE A 155
ILE A 145
ILE A 134
VAL A 106
LEU A 169
 None
 1.41A 1qhsA-1wlfA:
undetectable		 1qhsA-1wlfA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ylo HYPOTHETICAL PROTEIN
SF2450

(Shigella
flexneri) 		PF05343
(Peptidase_M42) 		5 VAL A 125
ILE A  79
ILE A 140
ILE A 107
VAL A  97
 None
 1.00A 1qhsA-1yloA:
2.1		 1qhsA-1yloA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zv9 CELLULOSOMAL
SCAFFOLDIN ADAPTOR
PROTEIN B

(Acetivibrio
cellulolyticus) 		PF00963
(Cohesin) 		6 SER A   6
VAL A 113
ILE A  26
PHE A 130
PHE A  91
LEU A 145
 None
 1.44A 1qhsA-1zv9A:
undetectable		 1qhsA-1zv9A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bco SUCCINYLGLUTAMATE
DESUCCINYLASE

(Vibrio
parahaemolyticus) 		PF04952
(AstE_AspA) 		5 VAL A  87
ILE A 245
ILE A  76
PHE A  93
VAL A  32
 None
 1.03A 1qhsA-2bcoA:
undetectable		 1qhsA-2bcoA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2btv PROTEIN (VP7 CORE
PROTEIN)

(Bluetongue
virus) 		no annotation 5 ILE P 174
ILE P 159
PHE P 129
ILE P 245
LEU P 186
 None
 0.95A 1qhsA-2btvP:
undetectable		 1qhsA-2btvP:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eke SUMO-CONJUGATING
ENZYME UBC9

(Saccharomyces
cerevisiae) 		PF00179
(UQ_con) 		5 ILE A  45
ILE A  60
ILE A  92
PHE A  77
LEU A  94
 None
 0.94A 1qhsA-2ekeA:
undetectable		 1qhsA-2ekeA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g39 ACETYL-COA HYDROLASE

(Pseudomonas
aeruginosa) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		5 SER A  34
ILE A 127
ILE A  25
ILE A  60
LEU A  62
 None
 0.86A 1qhsA-2g39A:
undetectable		 1qhsA-2g39A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gai DNA TOPOISOMERASE I

(Thermotoga
maritima) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		5 VAL A  11
ILE A 114
ILE A 119
PHE A 111
VAL A  30
 None
 0.95A 1qhsA-2gaiA:
undetectable		 1qhsA-2gaiA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2he9 NK-TUMOR RECOGNITION
PROTEIN

(Homo sapiens) 		PF00160
(Pro_isomerase) 		6 SER A 145
ILE A  13
ILE A 153
ILE A  73
PHE A  64
VAL A 143
 None
 1.34A 1qhsA-2he9A:
undetectable		 1qhsA-2he9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hj1 HYPOTHETICAL PROTEIN

(Haemophilus
influenzae) 		PF03658
(Ub-RnfH) 		5 ILE A  17
ILE A  47
ILE A  54
LEU A  56
GLN A  39
 None
 0.93A 1qhsA-2hj1A:
undetectable		 1qhsA-2hj1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i00 ACETYLTRANSFERASE,
GNAT FAMILY

(Enterococcus
faecalis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		5 SER A 147
ILE A  84
ILE A 127
ILE A 299
PHE A 305
 None
 0.90A 1qhsA-2i00A:
undetectable		 1qhsA-2i00A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o04 PECTATE LYASE

(Bacillus
subtilis) 		PF00544
(Pec_lyase_C) 		5 ILE A 154
ILE A 157
PHE A 159
ILE A  58
LEU A  41
 None
 0.92A 1qhsA-2o04A:
undetectable		 1qhsA-2o04A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r44 UNCHARACTERIZED
PROTEIN

(Cytophaga
hutchinsonii) 		PF07726
(AAA_3) 		5 VAL A 214
ILE A 217
ILE A  17
PHE A 278
LEU A  65
 None
 0.98A 1qhsA-2r44A:
undetectable		 1qhsA-2r44A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rad SUCCINOGLYCAN
BIOSYNTHESIS PROTEIN

(Bacillus cereus) 		PF05139
(Erythro_esteras) 		5 ILE A 234
ILE A 184
ILE A 255
LEU A 245
ARG A 198
 None
 0.92A 1qhsA-2radA:
5.0		 1qhsA-2radA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x4f MYOSIN LIGHT CHAIN
KINASE FAMILY MEMBER
4

(Homo sapiens) 		PF00069
(Pkinase) 		5 ILE A 243
ILE A 233
PHE A 189
VAL A 289
LEU A 228
 None
 0.95A 1qhsA-2x4fA:
undetectable		 1qhsA-2x4fA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2b SERINE
PALMITOYLTRANSFERASE

(Sphingobacterium
multivorum) 		PF00155
(Aminotran_1_2) 		5 VAL A 351
ILE A 366
ILE A 329
PHE A 390
VAL A 349
 None
 1.00A 1qhsA-3a2bA:
undetectable		 1qhsA-3a2bA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Plasmodium
vivax) 		PF02542
(YgbB) 		5 VAL A  52
ILE A 140
ILE A  68
VAL A  54
LEU A  47
 None
 0.99A 1qhsA-3b6nA:
undetectable		 1qhsA-3b6nA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bf8 ESTERASE YBFF

(Escherichia
coli) 		PF12697
(Abhydrolase_6) 		5 ILE A 229
ILE A 201
ILE A 112
LEU A  35
ARG A 246
 None
 0.96A 1qhsA-3bf8A:
2.4		 1qhsA-3bf8A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cq0 PUTATIVE
TRANSALDOLASE
YGR043C

(Saccharomyces
cerevisiae) 		PF00923
(TAL_FSA) 		5 ILE A  64
ILE A  89
ILE A  51
PHE A  93
LEU A  52
 None
 1.03A 1qhsA-3cq0A:
undetectable		 1qhsA-3cq0A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3daf 5,10-METHENYLTETRAHY
DROMETHANOPTERIN
HYDROGENASE

(Methanocaldococcus
jannaschii) 		PF03201
(HMD) 		6 SER A  63
VAL A 145
ILE A 166
ILE A 159
PHE A 187
LEU A 149
 FEG  A 501 (-4.4A)
None
None
None
None
FEG  A 501 (-4.9A)
 1.37A 1qhsA-3dafA:
undetectable		 1qhsA-3dafA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dea CUTINASE

(Colletotrichum
gloeosporioides) 		PF01083
(Cutinase) 		6 ILE A 157
ILE A 146
ILE A 175
PHE A 178
VAL A 161
LEU A 162
 None
 1.07A 1qhsA-3deaA:
3.5		 1qhsA-3deaA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3erv PUTATIVE C39-LIKE
PEPTIDASE

(Bacillus
anthracis) 		PF13529
(Peptidase_C39_2) 		5 VAL A 167
ILE A 169
PHE A 231
ILE A 154
VAL A 161
 None
 0.95A 1qhsA-3ervA:
undetectable		 1qhsA-3ervA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep) 		5 SER A 256
VAL A 178
ILE A 175
ILE A 349
ILE A 346
 MYR  A 500 ( 4.1A)
None
None
None
MYR  A 500 (-4.7A)
 0.97A 1qhsA-3fs1A:
undetectable		 1qhsA-3fs1A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwm HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE

(Mycolicibacterium
smegmatis) 		PF01648
(ACPS) 		6 VAL A  60
ILE A  61
ILE A  79
ILE A 101
VAL A  95
LEU A  97
 VAL  A  60 ( 0.6A)
ILE  A  61 ( 0.7A)
ILE  A  79 (-0.6A)
ILE  A 101 ( 0.7A)
VAL  A  95 ( 0.6A)
LEU  A  97 ( 0.6A)
 1.40A 1qhsA-3gwmA:
undetectable		 1qhsA-3gwmA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hp7 HEMOLYSIN, PUTATIVE

(Streptococcus
thermophilus) 		PF01479
(S4)
PF01728
(FtsJ) 		5 ILE A  87
ILE A  89
ILE A 164
PHE A 136
LEU A 165
 None
 1.00A 1qhsA-3hp7A:
undetectable		 1qhsA-3hp7A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3im9 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE

(Staphylococcus
aureus) 		PF00698
(Acyl_transf_1) 		5 SER A  89
ILE A 110
ILE A 214
PHE A 210
GLN A 248
 None
None
None
CA  A 601 ( 4.9A)
CA  A 601 (-3.5A)
 0.97A 1qhsA-3im9A:
undetectable		 1qhsA-3im9A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kbe SUPEROXIDE DISMUTASE
[CU-ZN]

(Caenorhabditis
elegans) 		PF00080
(Sod_Cu) 		5 ILE A  17
ILE A  96
PHE A  44
VAL A  13
LEU A  37
 None
 1.00A 1qhsA-3kbeA:
undetectable		 1qhsA-3kbeA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kbg 30S RIBOSOMAL
PROTEIN S4E

(Thermoplasma
acidophilum) 		PF00900
(Ribosomal_S4e)
PF01479
(S4) 		5 VAL A  68
ILE A  43
ILE A  44
VAL A  73
LEU A  61
 None
 1.04A 1qhsA-3kbgA:
undetectable		 1qhsA-3kbgA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kzw CYTOSOL
AMINOPEPTIDASE

(Staphylococcus
aureus) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		5 SER A 297
VAL A 485
ILE A 481
ILE A 176
ILE A 129
 None
 1.01A 1qhsA-3kzwA:
undetectable		 1qhsA-3kzwA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxf FERREDOXIN

(Novosphingobium
aromaticivorans) 		PF00111
(Fer2) 		6 VAL A  99
ILE A   4
ILE A  16
ILE A  33
VAL A  51
LEU A  36
 None
 1.17A 1qhsA-3lxfA:
undetectable		 1qhsA-3lxfA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3msu CITRATE SYNTHASE

(Francisella
tularensis) 		PF00285
(Citrate_synt) 		5 ILE A  45
ILE A  19
ILE A  21
VAL A  37
LEU A  23
 None
 0.88A 1qhsA-3msuA:
undetectable		 1qhsA-3msuA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qjp PUTATIVE
UNCHARACTERIZED
PROTEIN PH0350

(Pyrococcus
horikoshii) 		PF01881
(Cas_Cas6) 		5 VAL A   5
ILE A   3
ILE A  90
ILE A  28
VAL A 109
 None
 0.94A 1qhsA-3qjpA:
undetectable		 1qhsA-3qjpA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpc CUTINASE

(Fusarium solani) 		PF01083
(Cutinase) 		5 ILE A 141
ILE A 130
ILE A 159
VAL A 145
LEU A 146
 None
 1.04A 1qhsA-3qpcA:
3.5		 1qhsA-3qpcA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpd CUTINASE 1

(Aspergillus
oryzae) 		PF01083
(Cutinase) 		6 ILE A 136
PHE A 108
ILE A 165
PHE A 168
VAL A 151
LEU A 152
 None
 1.35A 1qhsA-3qpdA:
3.1		 1qhsA-3qpdA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qpd CUTINASE 1

(Aspergillus
oryzae) 		PF01083
(Cutinase) 		6 ILE A 147
ILE A 136
ILE A 165
PHE A 168
VAL A 151
LEU A 152
 None
 1.03A 1qhsA-3qpdA:
3.1		 1qhsA-3qpdA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg1 CD180 MOLECULE

(Bos taurus) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		5 SER A 226
ILE A 188
PHE A 206
ILE A 214
LEU A 242
 None
 0.99A 1qhsA-3rg1A:
undetectable		 1qhsA-3rg1A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5k FALCILYSIN

(Plasmodium
falciparum) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		5 VAL A 430
ILE A 460
PHE A 458
ILE A 486
LEU A 490
 None
 1.03A 1qhsA-3s5kA:
undetectable		 1qhsA-3s5kA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t32 AMINOTRANSFERASE,
CLASS I/II

(Bacillus
anthracis) 		PF00155
(Aminotran_1_2) 		5 SER A 255
VAL A  86
ILE A 244
ILE A 223
PHE A 102
 None
 0.98A 1qhsA-3t32A:
undetectable		 1qhsA-3t32A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsy FUSION PROTEIN
4-COUMARATE--COA
LIGASE 1,
RESVERATROL SYNTHASE

(Arabidopsis
thaliana;
Vitis vinifera) 		PF00195
(Chal_sti_synt_N)
PF00501
(AMP-binding)
PF02797
(Chal_sti_synt_C)
PF13193
(AMP-binding_C) 		5 VAL A 295
ILE A 273
VAL A 258
LEU A 265
GLN A 257
 None
 0.96A 1qhsA-3tsyA:
undetectable		 1qhsA-3tsyA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tw0 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF00092
(VWA) 		5 ILE A 509
ILE A 393
PHE A 395
ILE A 420
LEU A 411
 None
 1.04A 1qhsA-3tw0A:
undetectable		 1qhsA-3tw0A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zz1 BETA-D-GLUCOSIDE
GLUCOHYDROLASE

(Trichoderma
reesei) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		5 ILE A 399
ILE A 432
PHE A 434
ILE A 477
VAL A 517
 None
 0.92A 1qhsA-3zz1A:
undetectable		 1qhsA-3zz1A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2p RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		5 VAL A 297
ILE A 347
ILE A 341
ILE A 368
LEU A 366
 None
 0.93A 1qhsA-4a2pA:
undetectable		 1qhsA-4a2pA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		5 VAL A 297
ILE A 347
ILE A 341
ILE A 368
LEU A 366
 None
 1.04A 1qhsA-4a2qA:
2.6		 1qhsA-4a2qA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2w RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		5 VAL A 297
ILE A 347
ILE A 341
ILE A 368
LEU A 366
 None
 0.99A 1qhsA-4a2wA:
undetectable		 1qhsA-4a2wA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a9a RIBOSOME-INTERACTING
GTPASE 1

(Saccharomyces
cerevisiae) 		PF01926
(MMR_HSR1)
PF02824
(TGS)
PF16897
(MMR_HSR1_Xtn) 		5 VAL A 209
ILE A 206
ILE A 220
PHE A 222
ILE A 182
 None
 0.82A 1qhsA-4a9aA:
3.0		 1qhsA-4a9aA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		5 ILE A 317
ILE A 387
PHE A 389
VAL A 202
LEU A 420
 None
 0.98A 1qhsA-4bjuA:
undetectable		 1qhsA-4bjuA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN BETA-3

(Homo sapiens) 		PF00362
(Integrin_beta)
PF07965
(Integrin_B_tail)
PF07974
(EGF_2)
PF17205
(PSI_integrin) 		5 VAL B 359
ILE B 416
ILE B 399
PHE B 100
PHE B 370
 None
 1.02A 1qhsA-4cakB:
undetectable		 1qhsA-4cakB:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0o A-KINASE ANCHOR
PROTEIN 13

(Homo sapiens) 		PF00621
(RhoGEF) 		5 ILE A2078
ILE A2003
ILE A2164
VAL A2084
LEU A2085
 None
 1.01A 1qhsA-4d0oA:
undetectable		 1qhsA-4d0oA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fmz INTERNALIN

(Listeria
monocytogenes) 		PF12354
(Internalin_N)
PF12799
(LRR_4)
PF13855
(LRR_8) 		5 ILE A 244
ILE A 261
ILE A 283
LEU A 272
MET A 253
 None
 0.94A 1qhsA-4fmzA:
undetectable		 1qhsA-4fmzA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwi ABC-TYPE
DIPEPTIDE/OLIGOPEPTI
DE/NICKEL TRANSPORT
SYSTEM, ATPASE
COMPONENT

(Caldanaerobacter
subterraneus) 		PF00005
(ABC_tran)
PF08352
(oligo_HPY) 		5 ILE B 177
ILE B  51
ILE B  50
VAL B  69
LEU B  10
 None
 1.01A 1qhsA-4fwiB:
2.3		 1qhsA-4fwiB:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h09 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN

(Eubacterium
ventriosum) 		PF13306
(LRR_5) 		6 VAL A 239
ILE A 232
ILE A 255
ILE A 278
LEU A 289
MET A 270
 None
 1.39A 1qhsA-4h09A:
undetectable		 1qhsA-4h09A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hbs PUTATIVE HYDROLASE

(Bacteroides
ovatus) 		PF16396
(DUF5005) 		5 VAL A 420
ILE A 391
ILE A 328
VAL A  55
LEU A 426
 None
 0.91A 1qhsA-4hbsA:
undetectable		 1qhsA-4hbsA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwv PECTATE LYASE/AMB
ALLERGEN

(Acidovorax
citrulli) 		PF00544
(Pec_lyase_C) 		5 ILE A 211
ILE A 214
PHE A 216
ILE A  97
LEU A  67
 None
 0.97A 1qhsA-4hwvA:
undetectable		 1qhsA-4hwvA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxi KELCH-LIKE PROTEIN 3

(Homo sapiens) 		PF00651
(BTB)
PF07707
(BACK) 		5 VAL A  96
ILE A  93
ILE A  54
PHE A  75
ILE A  61
 None
 0.97A 1qhsA-4hxiA:
undetectable		 1qhsA-4hxiA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iqr HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep)
PF00105
(zf-C4) 		5 SER A 256
VAL A 178
ILE A 175
ILE A 349
ILE A 346
 MYR  A 401 ( 4.8A)
None
None
None
None
 0.90A 1qhsA-4iqrA:
undetectable		 1qhsA-4iqrA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jdz SER-ASP RICH
FIBRINOGEN/BONE
SIALOPROTEIN-BINDING
PROTEIN SDRD

(Staphylococcus
aureus) 		PF10425
(SdrG_C_C)
PF17210
(SdrD_B) 		5 VAL A 274
ILE A 272
ILE A 308
ILE A 317
VAL A 278
 None
 1.02A 1qhsA-4jdzA:
undetectable		 1qhsA-4jdzA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knc ALGINATE
BIOSYNTHESIS PROTEIN
ALGX

(Pseudomonas
aeruginosa) 		no annotation 5 ILE B 399
PHE B 425
ILE B 459
PHE B 438
VAL B 367
 None
 1.03A 1qhsA-4kncB:
undetectable		 1qhsA-4kncB:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l4u TRANSCRIPTIONAL
REGULATOR (NTRC
FAMILY)

(Aquifex
aeolicus) 		PF00072
(Response_reg)
PF00158
(Sigma54_activat) 		5 VAL A 362
ILE A 363
ILE A 375
PHE A 339
VAL A 384
 None
 1.01A 1qhsA-4l4uA:
3.5		 1qhsA-4l4uA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oja SUPEROXIDE DISMUTASE
[CU-ZN]

(Hydra vulgaris) 		PF00080
(Sod_Cu) 		5 ILE A  46
ILE A 148
PHE A  19
VAL A 118
LEU A   9
 None
 0.97A 1qhsA-4ojaA:
undetectable		 1qhsA-4ojaA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8p E3 UBIQUITIN-PROTEIN
LIGASE RING2,
UBIQUITIN-CONJUGATIN
G ENZYME E2 D3

(Homo sapiens) 		PF00179
(UQ_con)
PF13923
(zf-C3HC4_2) 		5 VAL L 302
ILE L 299
ILE L 254
PHE L 256
ARG L 205
 None
 1.04A 1qhsA-4r8pL:
undetectable		 1qhsA-4r8pL:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rul DNA TOPOISOMERASE 1

(Escherichia
coli) 		PF01131
(Topoisom_bac)
PF01396
(zf-C4_Topoisom)
PF01751
(Toprim)
PF08272
(Topo_Zn_Ribbon) 		6 VAL A   8
ILE A 142
ILE A 147
PHE A 139
VAL A  27
LEU A  21
 None
 1.24A 1qhsA-4rulA:
undetectable		 1qhsA-4rulA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xn3 TAIL SPIKE PROTEIN

(Salmonella
virus HK620) 		no annotation 5 VAL A 483
ILE A 480
ILE A 467
ILE A 502
VAL A 444
 None
 1.02A 1qhsA-4xn3A:
undetectable		 1qhsA-4xn3A:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dud YBGK

(Escherichia
coli) 		PF02626
(CT_A_B) 		6 VAL A 244
ILE A 261
ILE A 174
ILE A 278
PHE A 280
LEU A 200
 None
 1.16A 1qhsA-5dudA:
undetectable		 1qhsA-5dudA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e84 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo sapiens) 		PF00012
(HSP70) 		6 VAL A 342
ILE A 359
ILE A 356
PHE A 379
VAL A 345
LEU A 234
 None
 1.38A 1qhsA-5e84A:
undetectable		 1qhsA-5e84A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fds PROFILIN-2

(Hevea
brasiliensis) 		PF00235
(Profilin) 		5 VAL A  94
ILE A 103
ILE A  67
PHE A  42
LEU A  60
 None
 0.96A 1qhsA-5fdsA:
undetectable		 1qhsA-5fdsA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4i PHOSPHOLYASE

(Paenarthrobacter
aurescens) 		PF00202
(Aminotran_3) 		5 SER A 194
VAL A 237
ILE A 234
PHE A 221
VAL A 198
 None
 1.00A 1qhsA-5g4iA:
2.3		 1qhsA-5g4iA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzs GGDEF FAMILY PROTEIN

(Vibrio cholerae) 		PF00497
(SBP_bac_3) 		5 ILE A 227
ILE A 213
PHE A  66
VAL A 236
LEU A 240
 None
 0.99A 1qhsA-5gzsA:
undetectable		 1qhsA-5gzsA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5j THIOREDOXIN
REDUCTASE

(Giardia
intestinalis) 		PF07992
(Pyr_redox_2) 		5 VAL A 278
ILE A 112
ILE A  12
PHE A 249
ILE A  96
 None
None
None
FAD  A1001 ( 4.7A)
None
 0.99A 1qhsA-5m5jA:
undetectable		 1qhsA-5m5jA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN

(Rhodobacter
sphaeroides) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		5 VAL A 314
ILE A 123
PHE A 127
ILE A 122
ARG A 136
 None
 1.01A 1qhsA-5nv3A:
undetectable		 1qhsA-5nv3A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5thh TYROSINE--TRNA
LIGASE, CYTOPLASMIC

(Homo sapiens) 		PF00579
(tRNA-synt_1b) 		5 ILE A 101
ILE A  71
PHE A 117
VAL A 110
LEU A  63
 None
 0.95A 1qhsA-5thhA:
undetectable		 1qhsA-5thhA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj1 DNA TOPOISOMERASE 1

(Mycobacterium
tuberculosis) 		no annotation 6 VAL A  23
ILE A 141
ILE A 146
PHE A 138
VAL A  42
ARG A  30
 None
 1.11A 1qhsA-5uj1A:
undetectable		 1qhsA-5uj1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj1 DNA TOPOISOMERASE 1

(Mycobacterium
tuberculosis) 		no annotation 6 VAL A  23
ILE A 141
ILE A 146
PHE A 138
VAL A  42
LEU A  36
 None
 1.30A 1qhsA-5uj1A:
undetectable		 1qhsA-5uj1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v5x MCG133388, ISOFORM
CRA_Y

(Mus musculus) 		no annotation 5 VAL A 339
ILE A 315
ILE A 390
ILE A 362
VAL A 350
 None
 1.04A 1qhsA-5v5xA:
undetectable		 1qhsA-5v5xA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wch PROBABLE UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE FAF-X

(Homo sapiens) 		no annotation 6 SER A1692
ILE A1572
ILE A1585
PHE A1651
VAL A1694
LEU A1697
 None
 1.43A 1qhsA-5wchA:
undetectable		 1qhsA-5wchA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wxv ISOCHORISMATE LYASE

(Vibrio
anguillarum) 		no annotation 5 VAL A 108
ILE A 107
ILE A  37
ILE A  62
LEU A  58
 None
 0.95A 1qhsA-5wxvA:
undetectable		 1qhsA-5wxvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7u TREHALOSE SYNTHASE

(Thermobaculum
terrenum) 		no annotation 5 SER A 107
VAL A 102
ILE A 187
ILE A 184
LEU A 173
 None
 1.01A 1qhsA-5x7uA:
undetectable		 1qhsA-5x7uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x88 CUTINASE

(Malbranchea
cinnamomea) 		no annotation 6 ILE A 122
PHE A  94
ILE A 151
PHE A 154
VAL A 137
LEU A 138
 None
 1.35A 1qhsA-5x88A:
4.3		 1qhsA-5x88A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x88 CUTINASE

(Malbranchea
cinnamomea) 		no annotation 6 ILE A 133
ILE A 122
ILE A 151
PHE A 154
VAL A 137
LEU A 138
 None
 1.05A 1qhsA-5x88A:
4.3		 1qhsA-5x88A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xvn CRISPR-ASSOCIATED
ENDONUCLEASE CAS1

(Enterococcus
faecalis) 		PF01867
(Cas_Cas1) 		5 VAL A   6
ILE A  37
ILE A  62
VAL A   8
LEU A  42
 None
 0.89A 1qhsA-5xvnA:
undetectable		 1qhsA-5xvnA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi RIBOSOMAL PROTEIN
S24E, PUTATIVE

(Trichomonas
vaginalis) 		PF01282
(Ribosomal_S24e) 		5 VAL Y  54
ILE Y  56
ILE Y  24
ILE Y   8
PHE Y  22
 None
None
None
A  2 628 ( 4.5A)
None
 0.98A 1qhsA-5xyiY:
undetectable		 1qhsA-5xyiY:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yba PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Trichomonas
vaginalis) 		no annotation 5 ILE A  11
ILE A 150
ILE A  70
PHE A  61
VAL A 140
 None
 0.99A 1qhsA-5ybaA:
undetectable		 1qhsA-5ybaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6djw RBR-TYPE E3
UBIQUITIN
TRANSFERASE,RBR-TYPE
E3 UBIQUITIN
TRANSFERASE

(Bactrocera
dorsalis) 		no annotation 5 ILE A  72
ILE A  52
ILE A  85
VAL A  44
LEU A  46
 None
 1.02A 1qhsA-6djwA:
undetectable		 1qhsA-6djwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6djx RBR-TYPE E3
UBIQUITIN
TRANSFERASE,RBR-TYPE
E3 UBIQUITIN
TRANSFERASE

(Bactrocera
dorsalis) 		no annotation 5 ILE A  72
ILE A  52
ILE A  85
VAL A  44
LEU A  46
 None
 1.00A 1qhsA-6djxA:
undetectable		 1qhsA-6djxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eon BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 5 VAL A 557
ILE A 368
ILE A 371
PHE A 535
VAL A 555
 None
 0.92A 1qhsA-6eonA:
undetectable		 1qhsA-6eonA:
12.63