SIMILAR PATTERNS OF AMINO ACIDS FOR 1QFI_A_DVAA8
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c3l | SUBTILISIN-CARLSBERG (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 3 | THR A 211THR A 213PRO A 210 | None | 0.83A | 1qfiA-1c3lA:undetectable | 1qfiA-1c3lA:4.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cpt | CYTOCHROME P450-TERP (Pseudomonas sp.) |
PF00067(p450) | 3 | THR A 111THR A 109PRO A 107 | None | 0.76A | 1qfiA-1cptA:undetectable | 1qfiA-1cptA:5.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3d | [NIFE] HYDROGENASELARGE SUBUNIT (Desulfovibriodesulfuricans) |
PF00374(NiFeSe_Hases) | 3 | THR B 492THR B 493PRO B 491 | FNE B 543 (-3.8A)NoneFNE B 543 (-3.7A) | 0.75A | 1qfiA-1e3dB:undetectable | 1qfiA-1e3dB:4.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eu1 | DIMETHYL SULFOXIDEREDUCTASE (Rhodobactersphaeroides) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 3 | THR A 107THR A 109PRO A 106 | None | 0.82A | 1qfiA-1eu1A:undetectable | 1qfiA-1eu1A:1.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ffv | CUTL, MOLYBDOPROTEINOF CARBON MONOXIDEDEHYDROGENASE (Hydrogenophagapseudoflava) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 3 | THR B 766THR B 768PRO B 765 | None | 0.85A | 1qfiA-1ffvB:undetectable | 1qfiA-1ffvB:5.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7w | DIHYDROPYRIMIDINEDEHYDROGENASE (Sus scrofa) |
PF01180(DHO_dh)PF07992(Pyr_redox_2)PF14691(Fer4_20)PF14697(Fer4_21) | 3 | THR A 554THR A 555PRO A 553 | None | 0.71A | 1qfiA-1h7wA:undetectable | 1qfiA-1h7wA:1.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3u | ASPARTASE (Bacillus sp.YM55-1) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 3 | THR A 147THR A 149PRO A 146 | None | 0.81A | 1qfiA-1j3uA:undetectable | 1qfiA-1j3uA:2.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jio | CYTOCHROME P450107A1 (Saccharopolysporaerythraea) |
PF00067(p450) | 3 | THR A 99THR A 97PRO A 95 | None | 0.79A | 1qfiA-1jioA:undetectable | 1qfiA-1jioA:7.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qaf | PROTEIN (COPPERAMINE OXIDASE) (Escherichiacoli) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3)PF07833(Cu_amine_oxidN1) | 3 | THR A 688THR A 687PRO A 614 | None | 0.80A | 1qfiA-1qafA:undetectable | 1qfiA-1qafA:2.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tf1 | NEGATIVE REGULATOROF ALLANTOIN ANDGLYOXYLATEUTILIZATION OPERONS (Escherichiacoli) |
PF01614(IclR) | 3 | THR A 99THR A 100PRO A 98 | None | 0.80A | 1qfiA-1tf1A:undetectable | 1qfiA-1tf1A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tg5 | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (Arabidopsisthaliana) |
PF00903(Glyoxalase) | 3 | THR A 94THR A 95PRO A 93 | None | 0.77A | 1qfiA-1tg5A:undetectable | 1qfiA-1tg5A:3.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ux6 | THROMBOSPONDIN-1 (Homo sapiens) |
PF02412(TSP_3)PF05735(TSP_C) | 3 | THR A1035THR A1032PRO A1034 | None | 0.80A | 1qfiA-1ux6A:undetectable | 1qfiA-1ux6A:4.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w5d | PENICILLIN-BINDINGPROTEIN (Bacillussubtilis) |
PF02113(Peptidase_S13) | 3 | THR A 204THR A 203PRO A 230 | None | 0.80A | 1qfiA-1w5dA:undetectable | 1qfiA-1w5dA:3.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zlr | COAGULATION FACTORXI (Homo sapiens) |
PF00089(Trypsin) | 3 | THR A 37THR A 36PRO A 37 | None | 0.81A | 1qfiA-1zlrA:undetectable | 1qfiA-1zlrA:4.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b42 | XYLANASE INHIBITOR-I (Triticumaestivum) |
PF14541(TAXi_C)PF14543(TAXi_N) | 3 | THR A 107THR A 106PRO A 2 | None | 0.81A | 1qfiA-2b42A:undetectable | 1qfiA-2b42A:3.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c34 | INHIBITOR OFCYSTEINE PEPTIDASES (Leishmaniamexicana) |
PF09394(Inhibitor_I42) | 3 | THR A 31THR A 32PRO A 30 | None | 0.78A | 1qfiA-2c34A:undetectable | 1qfiA-2c34A:8.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c6r | DNA-BINDING STRESSRESPONSE PROTEIN,DPS FAMILY (Deinococcusradiodurans) |
PF00210(Ferritin) | 3 | THR A 164THR A 165PRO A 163 | None | 0.84A | 1qfiA-2c6rA:undetectable | 1qfiA-2c6rA:3.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4y | FLAGELLARHOOK-ASSOCIATEDPROTEIN 1 (Salmonellaenterica) |
no annotation | 3 | THR A 255THR A 256PRO A 247 | None | 0.84A | 1qfiA-2d4yA:undetectable | 1qfiA-2d4yA:3.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kgy | POSSIBLE EXPORTEDPROTEIN (Mycobacteriumtuberculosis) |
no annotation | 3 | THR A 16THR A 17PRO A 15 | None | 0.80A | 1qfiA-2kgyA:undetectable | 1qfiA-2kgyA:10.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ksk | SUGARCANE DEFENSIN 5 (Saccharumofficinarum) |
PF00304(Gamma-thionin) | 3 | THR A 4THR A 2PRO A 5 | None | 0.83A | 1qfiA-2kskA:undetectable | 1qfiA-2kskA:8.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ljp | RIBONUCLEASE PPROTEIN COMPONENT (Escherichiacoli) |
PF00825(Ribonuclease_P) | 3 | THR A 30THR A 34PRO A 31 | None | 0.84A | 1qfiA-2ljpA:undetectable | 1qfiA-2ljpA:8.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lvc | OBSCURIN-LIKEPROTEIN 1 (Homo sapiens) |
PF13927(Ig_3) | 3 | THR A 19THR A 67PRO A 69 | None | 0.85A | 1qfiA-2lvcA:undetectable | 1qfiA-2lvcA:6.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nnu | REGULATORY PROTEINE2 (Alphapapillomavirus9) |
PF00508(PPV_E2_N) | 3 | THR A 107THR A 104PRO A 106 | None | 0.78A | 1qfiA-2nnuA:undetectable | 1qfiA-2nnuA:5.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pff | FATTY ACID SYNTHASESUBUNIT BETA (Saccharomycescerevisiae) |
PF00698(Acyl_transf_1)PF16073(SAT) | 3 | THR B 55THR B 56PRO B 54 | None | 0.70A | 1qfiA-2pffB:undetectable | 1qfiA-2pffB:1.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r6f | EXCINUCLEASE ABCSUBUNIT A (Geobacillusstearothermophilus) |
PF00005(ABC_tran) | 3 | THR A 856THR A 857PRO A 855 | None | 0.78A | 1qfiA-2r6fA:undetectable | 1qfiA-2r6fA:2.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rfq | 3-HSA HYDROXYLASE,OXYGENASE (Rhodococcusjostii) |
PF02771(Acyl-CoA_dh_N)PF08028(Acyl-CoA_dh_2) | 3 | THR A 236THR A 237PRO A 235 | None | 0.77A | 1qfiA-2rfqA:undetectable | 1qfiA-2rfqA:3.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rs5 | HUMAN RHINOVIRUS 14COAT PROTEIN(SUBUNIT VP2) (Rhinovirus B) |
PF00073(Rhv) | 3 | THR 2 147THR 2 145PRO 2 149 | None | 0.81A | 1qfiA-2rs52:undetectable | 1qfiA-2rs52:7.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v7z | HEAT SHOCK COGNATE71 KDA PROTEIN (Rattusnorvegicus) |
PF00012(HSP70) | 3 | THR A 64THR A 66PRO A 63 | None | 0.83A | 1qfiA-2v7zA:undetectable | 1qfiA-2v7zA:3.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v9q | ROUNDABOUT HOMOLOG 1 (Homo sapiens) |
PF07679(I-set)PF13927(Ig_3) | 3 | THR A 228THR A 230PRO A 186 | None | 0.69A | 1qfiA-2v9qA:undetectable | 1qfiA-2v9qA:10.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vf8 | EXCINUCLEASE ABCSUBUNIT A (Deinococcusradiodurans) |
PF00005(ABC_tran) | 3 | THR A 761THR A 762PRO A 760 | None | 0.82A | 1qfiA-2vf8A:undetectable | 1qfiA-2vf8A:1.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wgr | GLUTATHIONEPEROXIDASE (Schistosomamansoni) |
PF00255(GSHPx) | 3 | THR A 152THR A 153PRO A 151 | NoneNonePOP A1170 (-4.4A) | 0.79A | 1qfiA-2wgrA:undetectable | 1qfiA-2wgrA:10.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xwb | COMPLEMENT FACTOR B (Homo sapiens) |
PF00084(Sushi)PF00089(Trypsin)PF00092(VWA) | 3 | THR F 587THR F 588PRO F 586 | None | 0.82A | 1qfiA-2xwbF:undetectable | 1qfiA-2xwbF:2.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z5l | TYLACTONE SYNTHASESTARTER MODULE ANDMODULES 1 & 2 (Streptomycesfradiae) |
PF08659(KR) | 3 | THR A 36THR A 37PRO A 35 | None | 0.75A | 1qfiA-2z5lA:undetectable | 1qfiA-2z5lA:6.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9x | SELENOCYSTEINE LYASE (Rattusnorvegicus) |
PF00266(Aminotran_5) | 3 | THR A 175THR A 176PRO A 174 | None | 0.84A | 1qfiA-3a9xA:undetectable | 1qfiA-3a9xA:2.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayx | MEMBRANE-BOUNDHYDROGENASE LARGESUBUNIT (Hydrogenovibriomarinus) |
PF00374(NiFeSe_Hases) | 3 | THR A 546THR A 547PRO A 545 | CYN A 605 (-3.7A)NoneCYN A 605 ( 3.6A) | 0.72A | 1qfiA-3ayxA:undetectable | 1qfiA-3ayxA:1.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bb8 | CDP-4-KETO-6-DEOXY-D-GLUCOSE-3-DEHYDRASE (Yersiniapseudotuberculosis) |
PF01041(DegT_DnrJ_EryC1) | 3 | THR A 122THR A 123PRO A 121 | PLP A 500 (-4.5A)PLP A 500 (-4.6A)None | 0.84A | 1qfiA-3bb8A:undetectable | 1qfiA-3bb8A:2.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gzd | SELENOCYSTEINE LYASE (Homo sapiens) |
PF00266(Aminotran_5) | 3 | THR C 187THR C 188PRO C 186 | None | 0.84A | 1qfiA-3gzdC:undetectable | 1qfiA-3gzdC:4.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1q | ETHANOLAMINEUTILIZATION PROTEINEUTJ (Carboxydothermushydrogenoformans) |
PF14450(FtsA) | 3 | THR A 147THR A 166PRO A 165 | None | 0.83A | 1qfiA-3h1qA:undetectable | 1qfiA-3h1qA:4.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hd8 | XYLANASE INHIBITOR (Triticumaestivum) |
PF14541(TAXi_C)PF14543(TAXi_N) | 3 | THR A 109THR A 108PRO A 4 | None | 0.82A | 1qfiA-3hd8A:undetectable | 1qfiA-3hd8A:3.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ik4 | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Herpetosiphonaurantiacus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | THR A 3THR A 4PRO A 2 | None | 0.81A | 1qfiA-3ik4A:undetectable | 1qfiA-3ik4A:3.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ikm | DNA POLYMERASESUBUNIT GAMMA-1 (Homo sapiens) |
PF00476(DNA_pol_A) | 3 | THR A 636THR A 638PRO A 635 | None | 0.78A | 1qfiA-3ikmA:undetectable | 1qfiA-3ikmA:0.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k9d | ALDEHYDEDEHYDROGENASE (Listeriamonocytogenes) |
PF00171(Aldedh) | 3 | THR A 122THR A 124PRO A 121 | CL A 465 (-4.1A)None CL A 465 (-4.1A) | 0.82A | 1qfiA-3k9dA:undetectable | 1qfiA-3k9dA:3.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kh5 | PROTEIN MJ1225 (Methanocaldococcusjannaschii) |
PF00571(CBS) | 3 | THR A 20THR A 21PRO A 19 | None | 0.80A | 1qfiA-3kh5A:undetectable | 1qfiA-3kh5A:3.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxm | ASPARTATECARBAMOYLTRANSFERASE (Yersinia pestis) |
PF00185(OTCace)PF02729(OTCace_N) | 3 | THR A 137THR A 139PRO A 136 | None | 0.79A | 1qfiA-3lxmA:undetectable | 1qfiA-3lxmA:3.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m8l | CAPSID PROTEIN (Felinecalicivirus) |
PF00915(Calici_coat) | 3 | THR A 132THR A 131PRO A 133 | None | 0.84A | 1qfiA-3m8lA:undetectable | 1qfiA-3m8lA:3.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mgg | METHYLTRANSFERASE (Methanosarcinamazei) |
PF13847(Methyltransf_31) | 3 | THR A 248THR A 254PRO A 150 | None | 0.84A | 1qfiA-3mggA:undetectable | 1qfiA-3mggA:7.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mpg | DIHYDROOROTASE (Bacillusanthracis) |
PF01979(Amidohydro_1) | 3 | THR A 390THR A 391PRO A 389 | None | 0.82A | 1qfiA-3mpgA:undetectable | 1qfiA-3mpgA:2.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3my7 | ALCOHOLDEHYDROGENASE/ACETALDEHYDE DEHYDROGENASE (Vibrioparahaemolyticus) |
PF00171(Aldedh) | 3 | THR A 117THR A 119PRO A 116 | CL A 453 ( 4.4A)None CL A 453 ( 4.6A) | 0.82A | 1qfiA-3my7A:undetectable | 1qfiA-3my7A:3.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nz4 | PHENYLALANINEAMMONIA-LYASE (Taxuscanadensis) |
PF00221(Lyase_aromatic) | 3 | THR A 127THR A 129PRO A 125 | None | 0.81A | 1qfiA-3nz4A:undetectable | 1qfiA-3nz4A:1.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3op7 | AMINOTRANSFERASECLASS I AND II (Streptococcussuis) |
PF00155(Aminotran_1_2) | 3 | THR A 153THR A 154PRO A 152 | None | 0.78A | 1qfiA-3op7A:undetectable | 1qfiA-3op7A:2.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pdm | COAT PROTEIN (Hibiscus latentSingapore virus) |
PF00721(TMV_coat) | 3 | THR P 103THR P 104PRO P 102 | None | 0.80A | 1qfiA-3pdmP:undetectable | 1qfiA-3pdmP:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rgw | MEMBRANE-BOUNDHYDROGENASE (NIFE)LARGE SUBUNIT HOXG (Cupriavidusnecator) |
PF00374(NiFeSe_Hases) | 3 | THR L 553THR L 554PRO L 552 | NFU L1004 (-3.8A)NoneNFU L1004 (-3.6A) | 0.73A | 1qfiA-3rgwL:undetectable | 1qfiA-3rgwL:1.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sc2 | SERINECARBOXYPEPTIDASE II(CPDW-II) (Triticumaestivum) |
PF00450(Peptidase_S10) | 3 | THR B 344THR B 346PRO B 342 | None | 0.76A | 1qfiA-3sc2B:undetectable | 1qfiA-3sc2B:7.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3usc | HYDROGENASE-1 LARGECHAIN (Escherichiacoli) |
PF00374(NiFeSe_Hases) | 3 | THR L 532THR L 533PRO L 531 | FCO L 601 (-3.7A)NoneFCO L 601 (-3.5A) | 0.70A | 1qfiA-3uscL:undetectable | 1qfiA-3uscL:2.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zqj | UVRABC SYSTEMPROTEIN A (Mycobacteriumtuberculosis) |
PF00005(ABC_tran) | 3 | THR A 873THR A 874PRO A 872 | None | 0.84A | 1qfiA-3zqjA:undetectable | 1qfiA-3zqjA:1.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zsu | TLL2057 PROTEIN (Thermosynechococcuselongatus) |
no annotation | 3 | THR A 103THR A 105PRO A 102 | None | 0.83A | 1qfiA-3zsuA:undetectable | 1qfiA-3zsuA:7.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a1r | LIP (Serratiamarcescens) |
PF12790(T6SS-SciN) | 3 | THR A 143THR A 145PRO A 142 | None | 0.83A | 1qfiA-4a1rA:undetectable | 1qfiA-4a1rA:5.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4av6 | K(+)-STIMULATEDPYROPHOSPHATE-ENERGIZED SODIUM PUMP (Thermotogamaritima) |
PF03030(H_PPase) | 3 | THR A 421THR A 423PRO A 420 | None | 0.78A | 1qfiA-4av6A:undetectable | 1qfiA-4av6A:2.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b2o | YMDBPHOSPHODIESTERASE (Bacillussubtilis) |
PF13277(YmdB) | 3 | THR A 232THR A 233PRO A 201 | None | 0.84A | 1qfiA-4b2oA:undetectable | 1qfiA-4b2oA:3.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btp | P1 (Pseudomonasphage phi8) |
no annotation | 3 | THR A 295THR A 297PRO A 299 | None | 0.66A | 1qfiA-4btpA:undetectable | 1qfiA-4btpA:3.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4byf | UNCONVENTIONALMYOSIN-IC (Homo sapiens) |
PF00063(Myosin_head)PF00612(IQ) | 3 | THR A 650THR A 647PRO A 649 | None | 0.78A | 1qfiA-4byfA:undetectable | 1qfiA-4byfA:1.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3o | HYDROGENASE-1 LARGESUBUNIT (Salmonellaenterica) |
PF00374(NiFeSe_Hases) | 3 | THR A 535THR A 536PRO A 534 | NFU A1004 (-3.7A)NoneNFU A1004 (-3.8A) | 0.74A | 1qfiA-4c3oA:undetectable | 1qfiA-4c3oA:2.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eog | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrococcusfuriosus) |
PF09455(Cas_DxTHG) | 3 | THR A 174THR A 176PRO A 173 | None | 0.81A | 1qfiA-4eogA:undetectable | 1qfiA-4eogA:5.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f1h | TYROSYL-DNAPHOSPHODIESTERASE 2 (Danio rerio) |
PF03372(Exo_endo_phos) | 3 | THR A 210THR A 211PRO A 209 | None | 0.64A | 1qfiA-4f1hA:undetectable | 1qfiA-4f1hA:29.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fnq | ALPHA-GALACTOSIDASEAGAB (Geobacillusstearothermophilus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 3 | THR A 187THR A 268PRO A 186 | None | 0.80A | 1qfiA-4fnqA:undetectable | 1qfiA-4fnqA:1.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h16 | SHORT CHAIN ALCOHOLDEHYDROGENASE-RELATED DEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 3 | THR A 149THR A 148PRO A 145 | NoneP6G A 305 ( 4.5A)None | 0.78A | 1qfiA-4h16A:undetectable | 1qfiA-4h16A:3.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k24 | ANTI-UPAR ANTIBODY,HEAVY CHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | THR H 116THR H 117PRO H 147 | None | 0.71A | 1qfiA-4k24H:undetectable | 1qfiA-4k24H:7.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pmh | PECTINESTERASE (Sitophilusoryzae) |
PF01095(Pectinesterase) | 3 | THR A 143THR A 111PRO A 113 | None | 0.80A | 1qfiA-4pmhA:undetectable | 1qfiA-4pmhA:3.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s3j | CORTICAL-LYTICENZYME (Bacillus cereus) |
PF00704(Glyco_hydro_18)PF01476(LysM) | 3 | THR A 162THR A 166PRO A 168 | None | 0.84A | 1qfiA-4s3jA:undetectable | 1qfiA-4s3jA:2.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tps | CHROMOSOMALREPLICATIONINITIATOR PROTEINDNAA (Bacillussubtilis) |
PF11638(DnaA_N) | 3 | THR B 31THR B 44PRO B 46 | None | 0.85A | 1qfiA-4tpsB:undetectable | 1qfiA-4tpsB:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uz1 | NOTUM (Homo sapiens) |
PF03283(PAE) | 3 | THR A 284THR A 282PRO A 287 | None | 0.81A | 1qfiA-4uz1A:undetectable | 1qfiA-4uz1A:2.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wzb | NITROGENASEMOLYBDENUM-IRONPROTEIN ALPHA CHAIN (Azotobactervinelandii) |
PF00148(Oxidored_nitro) | 3 | THR A 303THR A 305PRO A 302 | None | 0.83A | 1qfiA-4wzbA:undetectable | 1qfiA-4wzbA:4.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xvh | CARBOHYDRATEESTERASE FAMILY 2(CE2) (Chaetomium) |
PF13472(Lipase_GDSL_2) | 3 | THR A 288THR A 285PRO A 287 | None | 0.69A | 1qfiA-4xvhA:undetectable | 1qfiA-4xvhA:3.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zfm | PUTATIVE6-PHOSPHO-BETA-GALACTOBIOSIDASE (Geobacillusstearothermophilus) |
PF00232(Glyco_hydro_1) | 3 | THR A 303THR A 304PRO A 229 | None | 0.85A | 1qfiA-4zfmA:undetectable | 1qfiA-4zfmA:3.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6f | GATING RING OFPOTASSIUM CHANNELSUBFAMILY T MEMBER 1 (Gallus gallus) |
PF03493(BK_channel_a) | 3 | THR C 974THR C 973PRO C 975 | None | 0.85A | 1qfiA-5a6fC:undetectable | 1qfiA-5a6fC:1.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bw8 | UBIQUITIN-LIKEPROTEIN MDY2 (Saccharomycescerevisiae) |
PF16843(Get5_bdg) | 3 | THR D 21THR D 23PRO D 25 | None | 0.79A | 1qfiA-5bw8D:undetectable | 1qfiA-5bw8D:17.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bwy | PLASMEPSIN-2 (Plasmodiumfalciparum) |
PF00026(Asp) | 3 | THR A 114THR A 116PRO A 113 | None | 0.80A | 1qfiA-5bwyA:undetectable | 1qfiA-5bwyA:2.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dac | PUTATIVEUNCHARACTERIZEDPROTEIN,PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF13476(AAA_23) | 3 | THR A1240THR A1241PRO A1239 | None | 0.81A | 1qfiA-5dacA:undetectable | 1qfiA-5dacA:7.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dis | MALTOSE-BINDINGPERIPLASMICPROTEIN,NUCLEAR PORECOMPLEX PROTEINNUP214 (Escherichiacoli;Homo sapiens) |
PF13416(SBP_bac_8) | 3 | THR D1944THR D1946PRO D1943 | None | 0.68A | 1qfiA-5disD:undetectable | 1qfiA-5disD:2.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dyn | PUTATIVE PEPTIDASE (Bacteroidesfragilis) |
PF03415(Peptidase_C11) | 3 | THR B 388THR B 282PRO B 278 | None | 0.77A | 1qfiA-5dynB:undetectable | 1qfiA-5dynB:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eod | COAGULATION FACTORXI (Homo sapiens) |
PF00024(PAN_1)PF00089(Trypsin) | 3 | THR A 393THR A 390PRO A 392 | None | 0.71A | 1qfiA-5eodA:undetectable | 1qfiA-5eodA:1.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f3j | ANTIBODY 2D10 SINGLECHAIN VARIABLEFRAGMENT (Mus musculus) |
PF07686(V-set) | 3 | THR C 284THR C 283PRO C 178 | None | 0.84A | 1qfiA-5f3jC:undetectable | 1qfiA-5f3jC:4.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5foh | POLYSACCHARIDEMONOOXYGENASE (Neurosporacrassa) |
PF03443(Glyco_hydro_61) | 3 | THR A 46THR A 47PRO A 23 | None | 0.79A | 1qfiA-5fohA:undetectable | 1qfiA-5fohA:6.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5has | SEC7 (Thielaviaterrestris) |
PF12783(Sec7_N)PF16213(DCB) | 3 | THR A 66THR A 64PRO A 62 | None | 0.78A | 1qfiA-5hasA:undetectable | 1qfiA-5hasA:2.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hs8 | HTH-TYPETRANSCRIPTIONALREGULATOR YODB (Bacillussubtilis) |
PF01638(HxlR) | 3 | THR A 41THR A 39PRO A 43 | None | 0.71A | 1qfiA-5hs8A:undetectable | 1qfiA-5hs8A:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j78 | ACETALDEHYDEDEHYDROGENASE(ACETYLATING) (Parageobacillusthermoglucosidasius) |
PF00171(Aldedh) | 3 | THR A 144THR A 146PRO A 143 | ACT A1005 (-3.3A)NoneACT A1005 (-3.9A) | 0.79A | 1qfiA-5j78A:undetectable | 1qfiA-5j78A:2.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jfm | ALDEHYDEDEHYDROGENASE (Rhodopseudomonaspalustris) |
PF00171(Aldedh) | 3 | THR A 201THR A 203PRO A 200 | None | 0.79A | 1qfiA-5jfmA:undetectable | 1qfiA-5jfmA:3.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k9x | TRYPTOPHAN SYNTHASEALPHA CHAIN (Legionellapneumophila) |
PF00290(Trp_syntA) | 3 | THR A 157THR A 158PRO A 156 | None | 0.83A | 1qfiA-5k9xA:undetectable | 1qfiA-5k9xA:3.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l82 | ENTEROCOCCIN K1 (Enterococcusfaecium) |
no annotation | 3 | THR A 8THR A 10PRO A 7 | None | 0.85A | 1qfiA-5l82A:undetectable | 1qfiA-5l82A:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lj3 | PRE-MRNA-SPLICINGFACTOR BUD31 (Saccharomycescerevisiae) |
PF01125(G10) | 3 | THR L 22THR L 24PRO L 21 | None | 0.83A | 1qfiA-5lj3L:undetectable | 1qfiA-5lj3L:7.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqz | PUTATIVEBRANCHED-CHAIN-AMINO-ACIDAMINOTRANSFERASE (Archaeoglobusfulgidus) |
no annotation | 3 | THR A 228THR A 199PRO A 201 | TAM A 303 (-3.9A)NoneNone | 0.84A | 1qfiA-5mqzA:undetectable | 1qfiA-5mqzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ngk | GLUCOSYLCERAMIDASE (Bacteroidesthetaiotaomicron) |
PF02055(Glyco_hydro_30)PF17189(Glyco_hydro_30C) | 3 | THR A 68THR A 69PRO A 67 | None | 0.81A | 1qfiA-5ngkA:undetectable | 1qfiA-5ngkA:1.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5of4 | GENERALTRANSCRIPTION FACTORIIH SUBUNIT4,P52,GENERALTRANSCRIPTION FACTORIIH SUBUNIT 4 (Homo sapiens) |
no annotation | 3 | THR D 386THR D 388PRO D 385 | None | 0.74A | 1qfiA-5of4D:undetectable | 1qfiA-5of4D:10.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tte | E3 UBIQUITIN-PROTEINLIGASE ARIH1 (Homo sapiens) |
PF01485(IBR) | 3 | THR B 129THR B 131PRO B 127 | None | 0.83A | 1qfiA-5tteB:undetectable | 1qfiA-5tteB:9.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u03 | CTP SYNTHASE 1 (Homo sapiens) |
PF00117(GATase)PF06418(CTP_synth_N) | 3 | THR A 427THR A 428PRO A 426 | None | 0.85A | 1qfiA-5u03A:undetectable | 1qfiA-5u03A:2.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w1u | CARBOXYLIC ESTERHYDROLASE (Culexquinquefasciatus) |
PF00135(COesterase) | 3 | THR A 505THR A 502PRO A 504 | None | 0.62A | 1qfiA-5w1uA:undetectable | 1qfiA-5w1uA:2.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyn | PLATINUM SENSITIVITYPROTEIN 3 (Saccharomycescerevisiae) |
no annotation | 3 | THR A 182THR A 209PRO A 181 | None | 0.80A | 1qfiA-5xynA:undetectable | 1qfiA-5xynA:3.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6a8m | - (-) |
no annotation | 3 | THR A 63THR A 64PRO A 62 | None | 0.84A | 1qfiA-6a8mA:undetectable | 1qfiA-6a8mA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bq1 | PHOSPHATIDYLINOSITOL4-KINASE III ALPHA(PI4KA) (Homo sapiens) |
no annotation | 3 | THR A1074THR A1076PRO A1073 | None | 0.78A | 1qfiA-6bq1A:undetectable | 1qfiA-6bq1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fb3 | TENEURIN-2 (Gallus gallus) |
no annotation | 3 | THR A1826THR A1828PRO A1820 | None | 0.84A | 1qfiA-6fb3A:undetectable | 1qfiA-6fb3A:undetectable |