SIMILAR PATTERNS OF AMINO ACIDS FOR 1QCA_A_FUAA221_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1cia CHLORAMPHENICOL
ACETYLTRANSFERASE

(Escherichia
coli) 		PF00302
(CAT) 		5 THR A  94
PHE A 103
SER A 107
PHE A 135
LEU A 160
 None
 0.26A 1qcaA-1ciaA:
36.5		 1qcaA-1ciaA:
97.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dlc DELTA-ENDOTOXIN
CRYIIIA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 PHE A 640
SER A 610
PHE A 584
LEU A 514
 None
 0.95A 1qcaA-1dlcA:
0.0		 1qcaA-1dlcA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f1z TNSA ENDONUCLEASE

(Escherichia
coli) 		PF08721
(Tn7_Tnp_TnsA_C)
PF08722
(Tn7_Tnp_TnsA_N) 		4 THR A 236
PHE A 243
SER A 230
LEU A  64
 None
 1.09A 1qcaA-1f1zA:
0.0		 1qcaA-1f1zA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h39 SQUALENE--HOPENE
CYCLASE

(Alicyclobacillus
acidocaldarius) 		PF13243
(SQHop_cyclase_C)
PF13249
(SQHop_cyclase_N) 		4 CYH A 435
PHE A 166
PHE A 434
LEU A 225
 R03  A 800 ( 4.6A)
None
None
None
 1.11A 1qcaA-1h39A:
undetectable		 1qcaA-1h39A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i4e CASPASE-8

(Homo sapiens) 		PF00656
(Peptidase_C14) 		5 CYH B2345
THR B2341
PHE B2399
SER B2347
PHE B2310
 None
 1.34A 1qcaA-1i4eB:
0.0		 1qcaA-1i4eB:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5j ACONITATE HYDRATASE
2

(Escherichia
coli) 		PF00330
(Aconitase)
PF06434
(Aconitase_2_N)
PF11791
(Aconitase_B_N) 		4 CYH A 710
SER A 709
PHE A 593
LEU A 487
 F3S  A 868 (-2.2A)
F3S  A 868 (-3.3A)
None
None
 1.13A 1qcaA-1l5jA:
0.0		 1qcaA-1l5jA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lns X-PROLYL DIPEPTIDYL
AMINOPEPTIDASE

(Lactococcus
lactis) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C)
PF09168
(PepX_N) 		4 THR A 736
PHE A 685
PHE A 586
LEU A 593
 None
 1.02A 1qcaA-1lnsA:
0.0		 1qcaA-1lnsA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)

(Tobacco etch
virus) 		PF00863
(Peptidase_C4) 		4 THR A 180
PHE A 139
SER A 153
LEU A 204
 None
 0.99A 1qcaA-1lvmA:
0.0		 1qcaA-1lvmA:
21.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pd5 CHLORAMPHENICOL
ACETYLTRANSFERASE

(Escherichia
coli) 		PF00302
(CAT) 		5 CYH A  91
THR A  93
PHE A 102
PHE A 144
LEU A 158
 None
 0.64A 1qcaA-1pd5A:
32.4		 1qcaA-1pd5A:
47.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pd5 CHLORAMPHENICOL
ACETYLTRANSFERASE

(Escherichia
coli) 		PF00302
(CAT) 		5 THR A  93
PHE A 102
PHE A 134
PHE A 144
LEU A 158
 None
 0.90A 1qcaA-1pd5A:
32.4		 1qcaA-1pd5A:
47.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE

(Leishmania
mexicana) 		PF00342
(PGI) 		4 THR A 483
SER A 521
PHE A  75
LEU A 100
 None
 1.14A 1qcaA-1q50A:
undetectable		 1qcaA-1q50A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qlb FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Wolinella
succinogenes) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 CYH A 150
THR A 152
SER A 138
LEU A  15
 None
 0.93A 1qcaA-1qlbA:
undetectable		 1qcaA-1qlbA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ule GALECTIN-2

(Coprinopsis
cinerea) 		PF00337
(Gal-bind_lectin) 		4 SER A  27
PHE A  84
PHE A  39
LEU A  50
 None
 0.99A 1qcaA-1uleA:
undetectable		 1qcaA-1uleA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vd0 HEAD DECORATION
PROTEIN

(Escherichia
virus Lambda) 		PF02924
(HDPD) 		4 THR A 104
PHE A 101
PHE A  80
LEU A  46
 None
 1.13A 1qcaA-1vd0A:
undetectable		 1qcaA-1vd0A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y2f CELL DIVISION
PROTEIN ZIPA

(Escherichia
coli) 		PF04354
(ZipA_C) 		4 THR A  79
PHE A  77
SER A  21
LEU A  61
 None
 1.10A 1qcaA-1y2fA:
undetectable		 1qcaA-1y2fA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7h HEMOGLOBIN ALPHA
CHAIN

(Cerdocyon thous) 		PF00042
(Globin) 		4 THR A  39
PHE A  33
PHE A  98
LEU A 105
 HEM  A 200 ( 4.5A)
None
HEM  A 200 (-3.8A)
None
 1.10A 1qcaA-2b7hA:
undetectable		 1qcaA-2b7hA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bht CYSTEINE SYNTHASE B

(Escherichia
coli) 		PF00291
(PALP) 		4 THR A 175
PHE A 141
SER A 172
LEU A  76
 PLP  A 320 (-3.5A)
None
None
None
 0.86A 1qcaA-2bhtA:
undetectable		 1qcaA-2bhtA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5c PREPHENATE
DEHYDROGENASE

(Aquifex
aeolicus) 		PF02153
(PDH) 		4 THR A 120
PHE A  94
PHE A 143
LEU A 172
 None
 1.00A 1qcaA-2g5cA:
undetectable		 1qcaA-2g5cA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE

(Clostridium
acetobutylicum) 		PF08942
(DUF1919) 		4 CYH A 289
SER A 288
PHE A 243
LEU A 107
 None
 1.04A 1qcaA-2g6tA:
undetectable		 1qcaA-2g6tA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g9b CALBINDIN

(Rattus
norvegicus) 		PF13405
(EF-hand_6)
PF13499
(EF-hand_7) 		4 THR A  84
PHE A  88
SER A   9
LEU A 153
 None
 1.00A 1qcaA-2g9bA:
undetectable		 1qcaA-2g9bA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jau 5'(3')-DEOXYRIBONUCL
EOTIDASE

(Homo sapiens) 		PF06941
(NT5C) 		4 SER A  78
PHE A  75
PHE A  49
LEU A 108
 ATM  A1230 (-3.6A)
ATM  A1230 (-4.9A)
ATM  A1230 (-4.3A)
None
 1.13A 1qcaA-2jauA:
undetectable		 1qcaA-2jauA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lrn THIOL:DISULFIDE
INTERCHANGE PROTEIN

(Bacteroides sp.
4_3_47FAA) 		PF00578
(AhpC-TSA) 		4 CYH A  41
SER A  42
PHE A  38
LEU A  93
 None
 1.06A 1qcaA-2lrnA:
undetectable		 1qcaA-2lrnA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ml3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6

(Azotobacter
vinelandii) 		PF00353
(HemolysinCabind) 		4 PHE A 137
SER A 150
PHE A  87
LEU A  55
 None
 1.04A 1qcaA-2ml3A:
undetectable		 1qcaA-2ml3A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nn6 EXOSOME COMPLEX
EXONUCLEASE RRP43

(Homo sapiens) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		4 CYH C 233
SER C 116
PHE C 108
LEU C 248
 None
 1.04A 1qcaA-2nn6C:
undetectable		 1qcaA-2nn6C:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rsh ZINC FINGER PROTEIN
ZFAT

(Homo sapiens) 		no annotation 4 CYH A  19
PHE A  10
SER A  21
PHE A  17
 None
 1.13A 1qcaA-2rshA:
undetectable		 1qcaA-2rshA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uyy N-PAC PROTEIN

(Homo sapiens) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 CYH A 413
PHE A 272
PHE A 417
LEU A 399
 None
 1.08A 1qcaA-2uyyA:
undetectable		 1qcaA-2uyyA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vc2 INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF13517
(VCBS) 		4 PHE A 204
SER A 144
PHE A 131
LEU A  68
 None
 1.08A 1qcaA-2vc2A:
undetectable		 1qcaA-2vc2A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wab ENDOGLUCANASE E

(Ruminiclostridium
thermocellum) 		PF00657
(Lipase_GDSL) 		4 THR A  46
SER A  49
PHE A  67
PHE A 104
 None
None
GOL  A1345 (-4.2A)
None
 1.13A 1qcaA-2wabA:
undetectable		 1qcaA-2wabA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wya HYDROXYMETHYLGLUTARY
L-COA SYNTHASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C) 		4 CYH A 389
THR A 368
SER A 392
LEU A 266
 None
 1.02A 1qcaA-2wyaA:
undetectable		 1qcaA-2wyaA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpi ANAPHASE-PROMOTING
COMPLEX SUBUNIT CUT9

(Schizosaccharomyces
pombe) 		PF12895
(ANAPC3)
PF13181
(TPR_8)
PF13424
(TPR_12) 		4 THR A 440
PHE A 437
PHE A 446
LEU A 344
 None
None
None
ACE  B   1 ( 4.0A)
 0.98A 1qcaA-2xpiA:
undetectable		 1qcaA-2xpiA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7c TYPE-1 RESTRICTION
ENZYME ECOKI
SPECIFICITY PROTEIN

(Escherichia
coli) 		PF01420
(Methylase_S) 		4 SER A 296
PHE A 299
PHE A 290
LEU A 232
 None
 0.99A 1qcaA-2y7cA:
undetectable		 1qcaA-2y7cA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yij PHOSPHOLIPASE
A1-IIGAMMA

(Arabidopsis
thaliana) 		PF01764
(Lipase_3) 		4 CYH A 233
THR A 231
SER A 152
LEU A  43
 None
 0.97A 1qcaA-2yijA:
undetectable		 1qcaA-2yijA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yuj UBIQUITIN FUSION
DEGRADATION 1-LIKE

(Homo sapiens) 		PF03152
(UFD1) 		4 CYH A 148
THR A 150
SER A 178
LEU A  99
 None
 1.02A 1qcaA-2yujA:
undetectable		 1qcaA-2yujA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z63 TOLL-LIKE RECEPTOR
4, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 SER A 368
PHE A 396
PHE A 387
LEU A 434
 None
 1.13A 1qcaA-2z63A:
undetectable		 1qcaA-2z63A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zhp BLEOMYCIN RESISTANCE
PROTEIN

(Streptoalloteichus
hindustanus) 		no annotation 4 THR A  95
PHE A  86
PHE A 118
LEU A  63
 BY6  A 301 ( 4.3A)
BY6  A 301 (-4.4A)
None
BY6  A 301 ( 4.8A)
 1.09A 1qcaA-2zhpA:
undetectable		 1qcaA-2zhpA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afo NADH KINASE POS5

(Saccharomyces
cerevisiae) 		PF01513
(NAD_kinase) 		4 THR A 267
PHE A 178
SER A 276
LEU A 202
 NAI  A1001 (-3.7A)
MPD  A2001 ( 3.8A)
None
MPD  A2001 ( 4.8A)
 1.11A 1qcaA-3afoA:
undetectable		 1qcaA-3afoA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c4a PROBABLE TRYPTOPHAN
HYDROXYLASE VIOD

(Chromobacterium
violaceum) 		no annotation 4 CYH A 205
SER A 206
PHE A 187
LEU A 240
 None
 1.09A 1qcaA-3c4aA:
undetectable		 1qcaA-3c4aA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmm UBIQUITIN-ACTIVATING
ENZYME E1 1

(Saccharomyces
cerevisiae) 		PF00899
(ThiF)
PF09358
(E1_UFD)
PF10585
(UBA_e1_thiolCys)
PF16190
(E1_FCCH)
PF16191
(E1_4HB) 		4 SER A 153
PHE A 296
PHE A 366
LEU A 879
 None
 1.09A 1qcaA-3cmmA:
undetectable		 1qcaA-3cmmA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxm URACIL-DNA
GLYCOSYLASE

(Leishmania
naiffi) 		PF03167
(UDG) 		4 THR A 239
PHE A 245
PHE A 347
LEU A 227
 None
 0.82A 1qcaA-3cxmA:
undetectable		 1qcaA-3cxmA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d12 EPHRIN-B3

(Mus musculus) 		PF00812
(Ephrin) 		4 SER B 121
PHE B 117
PHE B 113
LEU B  61
 None
 1.04A 1qcaA-3d12B:
undetectable		 1qcaA-3d12B:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxi TOLL-LIKE RECEPTOR 4

(Homo sapiens) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 SER A 368
PHE A 396
PHE A 387
LEU A 434
 None
 1.12A 1qcaA-3fxiA:
undetectable		 1qcaA-3fxiA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ggg PREPHENATE
DEHYDROGENASE

(Aquifex
aeolicus) 		no annotation 4 THR D 120
PHE D  94
PHE D 143
LEU D 172
 None
 0.98A 1qcaA-3gggD:
undetectable		 1qcaA-3gggD:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gqp HEMOGLOBIN SUBUNIT
ALPHA

(Felis catus) 		PF00042
(Globin) 		4 THR A  39
PHE A  33
PHE A  98
LEU A 105
 HEM  A 143 ( 4.5A)
None
HEM  A 143 (-3.9A)
None
 1.09A 1qcaA-3gqpA:
undetectable		 1qcaA-3gqpA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hx3 RETINALDEHYDE-BINDIN
G PROTEIN 1

(Homo sapiens) 		PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N) 		4 THR A 217
SER A 214
PHE A 173
LEU A 258
 None
None
RET  A 400 (-3.6A)
RET  A 400 ( 4.9A)
 1.08A 1qcaA-3hx3A:
undetectable		 1qcaA-3hx3A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3g N-ACETYLTRANSFERASE

(Trypanosoma
brucei) 		PF00583
(Acetyltransf_1) 		4 PHE A 136
SER A 124
PHE A 130
LEU A  69
 None
 0.93A 1qcaA-3i3gA:
undetectable		 1qcaA-3i3gA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb4 VP1

(Parechovirus B) 		no annotation 4 THR A  99
PHE A  97
SER A 138
LEU A 163
 None
 0.98A 1qcaA-3jb4A:
undetectable		 1qcaA-3jb4A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8u HEME-BINDING PROTEIN
A

(Glaesserella
parasuis) 		PF00496
(SBP_bac_5) 		4 THR A 206
PHE A  97
SER A  53
LEU A  91
 None
 1.09A 1qcaA-3m8uA:
undetectable		 1qcaA-3m8uA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 THR A 162
PHE A  73
SER A  31
LEU A  67
 None
None
None
GOL  A 514 ( 4.7A)
 1.10A 1qcaA-3mzbA:
undetectable		 1qcaA-3mzbA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qnw CASPASE-6

(Homo sapiens) 		PF00656
(Peptidase_C14) 		4 CYH A 148
PHE B 206
SER A 150
PHE A 114
 None
 1.09A 1qcaA-3qnwA:
undetectable		 1qcaA-3qnwA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rha PUTRESCINE OXIDASE

(Paenarthrobacter
aurescens) 		PF01593
(Amino_oxidase) 		4 THR A 100
SER A  90
PHE A 370
PHE A 107
 None
 1.11A 1qcaA-3rhaA:
undetectable		 1qcaA-3rhaA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s4u PHND, SUBUNIT OF
ALKYLPHOSPHONATE ABC
TRANSPORTER

(Escherichia
coli) 		PF12974
(Phosphonate-bd) 		4 PHE A  81
PHE A 246
PHE A 224
LEU A   7
 None
 1.07A 1qcaA-3s4uA:
undetectable		 1qcaA-3s4uA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3te7 RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE]

(Homo sapiens) 		PF02525
(Flavodoxin_2) 		4 THR A 148
PHE A 190
PHE A 106
LEU A 168
 FAD  A 232 (-4.1A)
None
FAD  A 232 ( 4.6A)
None
 1.01A 1qcaA-3te7A:
undetectable		 1qcaA-3te7A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1d ATLASTIN

(Drosophila
melanogaster) 		PF02263
(GBP) 		4 PHE A 189
SER A 146
PHE A 168
LEU A 228
 None
 1.00A 1qcaA-3x1dA:
undetectable		 1qcaA-3x1dA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zf8 MANNAN POLYMERASE
COMPLEXES SUBUNIT
MNN9

(Saccharomyces
cerevisiae) 		PF03452
(Anp1) 		4 THR A 121
PHE A 148
PHE A 126
LEU A 137
 None
 1.11A 1qcaA-3zf8A:
undetectable		 1qcaA-3zf8A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bhi GAMMA-BUTYROBETAINE
DIOXYGENASE

(Homo sapiens) 		PF02668
(TauD)
PF06155
(DUF971) 		4 PHE A 259
SER A 254
PHE A 310
LEU A 346
 None
 1.01A 1qcaA-4bhiA:
undetectable		 1qcaA-4bhiA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bkf EPHRIN-B3

(Homo sapiens) 		PF00812
(Ephrin) 		4 SER C 121
PHE C 117
PHE C 113
LEU C  61
 None
 1.04A 1qcaA-4bkfC:
undetectable		 1qcaA-4bkfC:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bmb GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 CYH A  78
PHE A  46
PHE A  64
LEU A 138
 None
 1.04A 1qcaA-4bmbA:
undetectable		 1qcaA-4bmbA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 PHE A 204
SER A 144
PHE A 131
LEU A  68
 None
 1.11A 1qcaA-4cakA:
undetectable		 1qcaA-4cakA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		4 CYH A 643
PHE A 666
PHE A 642
LEU A 659
 None
 1.06A 1qcaA-4ecnA:
undetectable		 1qcaA-4ecnA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f99 CELL DIVISION CYCLE
7-RELATED PROTEIN
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 CYH A 462
PHE A 151
SER A 409
PHE A 404
 None
 1.14A 1qcaA-4f99A:
undetectable		 1qcaA-4f99A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fb3 LARGE T ANTIGEN

(Mus musculus
polyomavirus 1) 		PF02217
(T_Ag_DNA_bind) 		4 CYH A 338
PHE A 394
PHE A 349
LEU A 300
 None
 1.02A 1qcaA-4fb3A:
undetectable		 1qcaA-4fb3A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fqz GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 CYH A  78
PHE A  46
PHE A  64
LEU A 138
 EDO  A 404 (-3.6A)
None
None
None
 1.06A 1qcaA-4fqzA:
undetectable		 1qcaA-4fqzA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwt ELONGATION FACTOR
TS, ELONGATION
FACTOR TU, LINKER, Q
BETA REPLICASE

(Escherichia
coli;
Escherichia
virus Qbeta) 		PF00009
(GTP_EFTU)
PF00889
(EF_TS)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2)
PF03431
(RNA_replicase_B) 		4 PHE A 890
SER A 864
PHE A 503
LEU A 562
 None
 0.97A 1qcaA-4fwtA:
undetectable		 1qcaA-4fwtA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hvt POST-PROLINE
CLEAVING ENZYME

(Rickettsia
typhi) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		4 THR A 357
SER A 402
PHE A 354
LEU A 322
 None
 1.12A 1qcaA-4hvtA:
undetectable		 1qcaA-4hvtA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ljp E3 UBIQUITIN-PROTEIN
LIGASE RNF31

(Homo sapiens) 		no annotation 4 CYH A 898
SER A 899
PHE A 932
PHE A 905
 ZN  A1102 (-2.4A)
None
None
None
 1.04A 1qcaA-4ljpA:
undetectable		 1qcaA-4ljpA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		4 THR D 354
PHE D 361
PHE D 420
LEU D 334
 None
 1.08A 1qcaA-4ngeD:
undetectable		 1qcaA-4ngeD:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nhy 2-OXOGLUTARATE AND
IRON-DEPENDENT
OXYGENASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF10637
(Ofd1_CTDD)
PF13661
(2OG-FeII_Oxy_4) 		4 CYH A 435
SER A 256
PHE A 538
LEU A 500
 None
 0.87A 1qcaA-4nhyA:
undetectable		 1qcaA-4nhyA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pii N-GLYCOSYLASE/DNA
LYASE

(Pyrococcus
furiosus) 		PF09171
(AGOG) 		4 SER A  72
PHE A  67
PHE A  42
LEU A 119
 None
 0.93A 1qcaA-4piiA:
undetectable		 1qcaA-4piiA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4png LD04004P

(Drosophila
melanogaster) 		PF00043
(GST_C)
PF13417
(GST_N_3) 		4 PHE A 174
SER A 166
PHE A 209
PHE A 108
 None
None
None
GSF  A2001 (-3.8A)
 1.01A 1qcaA-4pngA:
undetectable		 1qcaA-4pngA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qpk PHOSPHOTRANSFERASE

(Brucella
abortus) 		PF10090
(HPTransfase) 		4 THR A  89
PHE A  99
PHE A  64
LEU A 137
 None
None
GOL  A 301 (-4.5A)
None
 1.09A 1qcaA-4qpkA:
undetectable		 1qcaA-4qpkA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qts CRISPR TYPE
III-ASSOCIATED RAMP
PROTEIN CSM3

(Methanocaldococcus
jannaschii) 		PF03787
(RAMPs) 		4 PHE C 163
SER C  53
PHE C  92
LEU C 231
 None
 0.89A 1qcaA-4qtsC:
undetectable		 1qcaA-4qtsC:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4k UNCHARACTERIZED
PROTEIN

(Bacteroides
caccae) 		no annotation 4 THR A  51
PHE A  50
PHE A  43
LEU A 135
 None
None
ACT  A 202 ( 4.9A)
PEU  A 204 ( 4.0A)
 1.13A 1qcaA-4r4kA:
undetectable		 1qcaA-4r4kA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wvw GALECTIN

(Gallus gallus) 		PF00337
(Gal-bind_lectin) 		4 CYH A  77
PHE A  45
PHE A  63
LEU A 137
 None
 1.04A 1qcaA-4wvwA:
undetectable		 1qcaA-4wvwA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yte H(2)-FORMING
METHYLENETETRAHYDROM
ETHANOPTERIN
DEHYDROGENASE-RELATE
D PROTEIN MJ0715

(Methanocaldococcus
jannaschii) 		no annotation 4 CYH A 113
THR A 115
SER A 141
LEU A  48
 None
 0.92A 1qcaA-4yteA:
undetectable		 1qcaA-4yteA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amq RNA POLYMERASE L

(California
encephalitis
orthobunyavirus) 		PF04196
(Bunya_RdRp)
PF15518
(L_protein_N) 		4 THR A 649
SER A 644
PHE A 682
LEU A1257
 None
 1.10A 1qcaA-5amqA:
3.1		 1qcaA-5amqA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c3m PUTATIVE
6-PHOSPHO-BETA-GLUCO
SIDASE

(Geobacillus
stearothermophilus) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		4 THR A  85
PHE A 148
PHE A  83
LEU A  24
 None
 0.91A 1qcaA-5c3mA:
undetectable		 1qcaA-5c3mA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ctm BETA-LACTAMASE

(Bacillus
pumilus) 		PF00905
(Transpeptidase) 		4 THR A 264
PHE A  75
SER A 196
LEU A 236
 None
 1.07A 1qcaA-5ctmA:
undetectable		 1qcaA-5ctmA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e9j MRNA CAP GUANINE-N7
METHYLTRANSFERASE,MR
NA CAP GUANINE-N7
METHYLTRANSFERASE

(Homo sapiens) 		PF03291
(Pox_MCEL) 		4 CYH A 287
PHE A 375
SER A 290
LEU A 183
 None
 1.10A 1qcaA-5e9jA:
undetectable		 1qcaA-5e9jA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fif CARBOXYLASE

(Deinococcus
radiodurans) 		PF01039
(Carboxyl_trans) 		4 CYH A 369
PHE A 414
PHE A 365
LEU A 328
 None
 1.08A 1qcaA-5fifA:
undetectable		 1qcaA-5fifA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqr LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE TDR

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 PHE B 145
SER B 162
PHE B 141
LEU B 155
 None
 1.05A 1qcaA-5gqrB:
undetectable		 1qcaA-5gqrB:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzg GALECTIN-8

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 CYH A  78
PHE A  46
PHE A  64
LEU A 138
 None
 1.05A 1qcaA-5gzgA:
undetectable		 1qcaA-5gzgA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7t CLASS IV CHITINASE

(Cryptomeria
japonica) 		no annotation 4 PHE A  43
SER A  32
PHE A  11
LEU A 195
 None
 0.86A 1qcaA-5h7tA:
undetectable		 1qcaA-5h7tA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 THR B 272
SER B 252
PHE B 360
LEU B 385
 None
 1.08A 1qcaA-5ip9B:
undetectable		 1qcaA-5ip9B:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE

(Paecilomyces
sp.
'thermophila') 		no annotation 4 THR B 247
PHE B 285
PHE B  31
LEU B 271
 None
 0.92A 1qcaA-5jvvB:
undetectable		 1qcaA-5jvvB:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdm MAJOR TEGUMENT
PROTEIN

(Human
gammaherpesvirus
4) 		PF12818
(Tegument_dsDNA) 		4 CYH D 505
SER D 506
PHE D 400
LEU D 551
 None
 1.13A 1qcaA-5kdmD:
undetectable		 1qcaA-5kdmD:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kew VTRC PROTEIN

(Vibrio
parahaemolyticus) 		no annotation 4 PHE B 150
SER B 131
PHE B 101
LEU B 158
 6SB  B 301 (-2.6A)
None
None
None
 1.02A 1qcaA-5kewB:
undetectable		 1qcaA-5kewB:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kyu PROTEIN TRANSPORT
PROTEIN SEC24D

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 PHE B 581
SER B 632
PHE B 443
LEU B 470
 None
 0.86A 1qcaA-5kyuB:
undetectable		 1qcaA-5kyuB:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9g TRANSCRIPTION FACTOR
TFIIIB COMPONENT B''
HOMOLOG

(Homo sapiens) 		PF15963
(Myb_DNA-bind_7) 		4 THR C 320
PHE C 322
SER C 316
PHE C 311
 None
 0.98A 1qcaA-5n9gC:
undetectable		 1qcaA-5n9gC:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nlh GALECTIN

(Gallus gallus) 		no annotation 4 CYH A  60
PHE A  33
PHE A  47
LEU A 121
 None
 1.09A 1qcaA-5nlhA:
undetectable		 1qcaA-5nlhA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nsq AMINOPEPTIDASE,
PUTATIVE

(Trypanosoma
brucei) 		PF00883
(Peptidase_M17) 		4 CYH A 321
SER A 205
PHE A 320
LEU A 341
 None
 1.04A 1qcaA-5nsqA:
undetectable		 1qcaA-5nsqA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ntf AMINOPEPTIDASE

(Trypanosoma
cruzi) 		PF00883
(Peptidase_M17) 		4 CYH A 320
SER A 204
PHE A 319
LEU A 340
 None
 1.04A 1qcaA-5ntfA:
undetectable		 1qcaA-5ntfA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nth PUTATIVE
AMINOPEPTIDASE

(Leishmania
major) 		PF00883
(Peptidase_M17) 		4 CYH A 331
SER A 213
PHE A 330
LEU A 359
 None
 1.10A 1qcaA-5nthA:
undetectable		 1qcaA-5nthA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5twa BAK-2 PROTEIN
BCL-X HOMOLOGOUS
PROTEIN, BHP2

(Geodia
cydonium;
Lubomirskia
baicalensis) 		PF00452
(Bcl-2)
no annotation 		4 THR A 166
SER A 161
PHE A 146
LEU D  75
 None
None
None
EDO  D 102 ( 4.5A)
 1.09A 1qcaA-5twaA:
undetectable		 1qcaA-5twaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y30 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 4 THR A 134
PHE A 135
SER A  83
LEU A 151
 None
 1.04A 1qcaA-5y30A:
undetectable		 1qcaA-5y30A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1

(Homo sapiens) 		no annotation 4 THR B 134
PHE B 135
SER B  83
LEU B 151
 None
 1.03A 1qcaA-5y31B:
undetectable		 1qcaA-5y31B:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c1d UNCONVENTIONAL
MYOSIN-IB

(Rattus
norvegicus) 		no annotation 4 PHE P 251
PHE P 152
PHE P 208
LEU P 225
 None
 1.11A 1qcaA-6c1dP:
undetectable		 1qcaA-6c1dP:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dip NOCTURNIN

(Homo sapiens) 		no annotation 4 CYH A 273
SER A 276
PHE A 245
LEU A 238
 None
 0.84A 1qcaA-6dipA:
undetectable		 1qcaA-6dipA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6enz ACIDIC AMINO ACID
DECARBOXYLASE GADL1

(Mus musculus) 		no annotation 4 THR A 419
PHE A 394
PHE A 262
LEU A 316
 None
 0.98A 1qcaA-6enzA:
undetectable		 1qcaA-6enzA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIQ

(Salmonella
enterica) 		no annotation 4 THR A 188
PHE A 193
PHE G  81
LEU A 239
 None
 1.11A 1qcaA-6f2dA:
undetectable		 1qcaA-6f2dA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5d ATP SYNTHASE DELTA
SUBUNIT
ATP SYNTHASE EPSILON
SUBUNIT
ATP SYNTHASE GAMMA
SUBUNIT

(Trypanosoma
brucei) 		no annotation 4 THR G  49
PHE G  53
PHE H  98
LEU I  12
 None
 0.98A 1qcaA-6f5dG:
undetectable		 1qcaA-6f5dG:
16.10