SIMILAR PATTERNS OF AMINO ACIDS FOR 1Q13_A_TESA501_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1br2 | MYOSIN (Gallus gallus) |
PF00063(Myosin_head)PF02736(Myosin_N) | 4 | TYR A 484HIS A 585PRO A 531VAL A 537 | None | 1.36A | 1q13A-1br2A:undetectable | 1q13A-1br2A:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d7a | PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE (Escherichiacoli) |
PF00731(AIRC) | 4 | TYR A 63HIS A 38PRO A 77VAL A 42 | None | 1.11A | 1q13A-1d7aA:undetectable | 1q13A-1d7aA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgp | ARISTOLOCHENESYNTHASE (Penicilliumroqueforti) |
no annotation | 4 | TYR A 129GLU A 149PRO A 148VAL A 110 | None | 1.34A | 1q13A-1dgpA:undetectable | 1q13A-1dgpA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8w | NADH PEROXIDASE (Enterococcusfaecalis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | TYR A 217GLU A 117PRO A 115VAL A 242 | None | 1.37A | 1q13A-1f8wA:undetectable | 1q13A-1f8wA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1glo | CATHEPSIN S (Homo sapiens) |
PF00112(Peptidase_C1) | 4 | TYR A 148HIS A 205GLU A 192VAL A 182 | None | 1.15A | 1q13A-1gloA:undetectable | 1q13A-1gloA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mda | METHYLAMINEDEHYDROGENASE (HEAVYSUBUNIT) (Paracoccusdenitrificans) |
PF06433(Me-amine-dh_H) | 4 | HIS H 169GLU H 360PRO H 39VAL H 122 | None | 1.43A | 1q13A-1mdaH:undetectable | 1q13A-1mdaH:21.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1q5m | PROSTAGLANDIN-E29-REDUCTASE (Oryctolaguscuniculus) |
PF00248(Aldo_ket_red) | 5 | TYR A 24TYR A 55HIS A 117GLU A 224VAL A 306 | NoneNDP A1003 (-4.9A)NDP A1003 (-4.3A)NoneNone | 0.19A | 1q13A-1q5mA:55.8 | 1q13A-1q5mA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1umb | 2-OXO ACIDDEHYDROGENASE ALPHASUBUNIT (Thermusthermophilus) |
PF00676(E1_dh) | 4 | TYR A 94TYR A 95HIS A 273GLU A 202 | TDP A1402 (-4.5A)TDP A1402 (-4.3A)TDP A1402 (-4.3A)None | 0.95A | 1q13A-1umbA:undetectable | 1q13A-1umbA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w07 | ACYL-COA OXIDASE (Arabidopsisthaliana) |
PF01756(ACOX)PF02770(Acyl-CoA_dh_M)PF14749(Acyl-CoA_ox_N) | 4 | TYR A 457GLU A 372PRO A 371VAL A 434 | None | 1.38A | 1q13A-1w07A:undetectable | 1q13A-1w07A:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wyt | GLYCINEDEHYDROGENASE(DECARBOXYLATING)SUBUNIT 1GLYCINEDEHYDROGENASESUBUNIT 2(P-PROTEIN) (Thermusthermophilus) |
PF02347(GDC-P) | 4 | TYR A 3HIS B 83PRO A 42VAL A 50 | None | 1.43A | 1q13A-1wytA:undetectable | 1q13A-1wytA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xzw | PURPLE ACIDPHOSPHATASE (Ipomoea batatas) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 4 | TYR A 289TYR A 378GLU A 307PRO A 308 | None | 1.37A | 1q13A-1xzwA:undetectable | 1q13A-1xzwA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8a | HYPOTHETICAL PROTEINAF1437 (Archaeoglobusfulgidus) |
no annotation | 4 | TYR A 53TYR A 49GLU A 185VAL A 178 | None | 1.25A | 1q13A-1y8aA:undetectable | 1q13A-1y8aA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yni | SUCCINYLARGININEDIHYDROLASE (Escherichiacoli) |
PF04996(AstB) | 4 | TYR A 18HIS A 16GLU A 324PRO A 322 | None | 1.29A | 1q13A-1yniA:undetectable | 1q13A-1yniA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ynq | OXIDOREDUCTASE (Bacillushalodurans) |
PF00248(Aldo_ket_red) | 4 | TYR A 243GLU A 180PRO A 179VAL A 195 | None | 1.25A | 1q13A-1ynqA:23.9 | 1q13A-1ynqA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ynq | OXIDOREDUCTASE (Bacillushalodurans) |
PF00248(Aldo_ket_red) | 4 | TYR A 243GLU A 180PRO A 179VAL A 250 | None | 1.11A | 1q13A-1ynqA:23.9 | 1q13A-1ynqA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2az4 | HYPOTHETICAL PROTEINEF2904 (Enterococcusfaecalis) |
PF12706(Lactamase_B_2) | 4 | TYR A 186HIS A 97PRO A 408VAL A 218 | None ZN A 602 (-3.3A)NoneNone | 1.20A | 1q13A-2az4A:undetectable | 1q13A-2az4A:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3o | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Desulfovibrioafricanus) |
PF01558(POR)PF01855(POR_N)PF02775(TPP_enzyme_C)PF10371(EKR)PF13484(Fer4_16)PF17147(PFOR_II) | 4 | TYR A 479HIS A 467GLU A 285PRO A 414 | None | 1.27A | 1q13A-2c3oA:undetectable | 1q13A-2c3oA:13.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f9g | MITOGEN-ACTIVATEDPROTEIN KINASE FUS3 (Saccharomycescerevisiae) |
PF00069(Pkinase) | 4 | TYR A 119TYR A 116GLU A 318PRO A 315 | None | 1.30A | 1q13A-2f9gA:undetectable | 1q13A-2f9gA:23.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fvl | ALDO-KETO REDUCTASEFAMILY 1, MEMBER C4 (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | TYR A 24TYR A 55HIS A 117VAL A 306 | NoneNAP A1001 (-4.7A)NAP A1001 (-4.4A)None | 0.58A | 1q13A-2fvlA:52.3 | 1q13A-2fvlA:78.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g3n | ALPHA-GLUCOSIDASE (Sulfolobussolfataricus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 4 | TYR A 186GLU A 489PRO A 490VAL A 206 | None | 1.13A | 1q13A-2g3nA:4.7 | 1q13A-2g3nA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hh8 | HYPOTHETICAL PROTEINYDFO (Escherichiacoli) |
PF07166(DUF1398) | 4 | TYR A 42TYR A 40GLU A 47VAL A 19 | None | 1.24A | 1q13A-2hh8A:undetectable | 1q13A-2hh8A:18.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ipj | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C2 (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | TYR A 55HIS A 117GLU A 224PRO A 226 | FFA A 325 ( 4.3A)FFA A 325 ( 3.8A)NoneNone | 0.85A | 1q13A-2ipjA:52.1 | 1q13A-2ipjA:78.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pg3 | QUEUOSINEBIOSYNTHESIS PROTEINQUEC (Pectobacteriumatrosepticum) |
PF06508(QueC) | 4 | TYR A 25GLU A 157PRO A 159VAL A 6 | None | 1.40A | 1q13A-2pg3A:undetectable | 1q13A-2pg3A:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qlv | PROTEIN SIP2 (Saccharomycescerevisiae) |
PF04739(AMPKBI)PF16561(AMPK1_CBM) | 4 | TYR B 323GLU B 320PRO B 316VAL B 312 | None | 1.42A | 1q13A-2qlvB:undetectable | 1q13A-2qlvB:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzc | TRANSCRIPTIONALACTIVATOR TENA-1 (Sulfolobussolfataricus) |
PF03070(TENA_THI-4) | 4 | TYR A 140TYR A 162HIS A 88GLU A 198 | GOL A 215 ( 3.5A)GOL A 215 (-4.7A)NoneIMD A 214 (-2.7A) | 1.24A | 1q13A-2qzcA:undetectable | 1q13A-2qzcA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wb7 | PT26-6P (Thermococcussp. 26-2) |
no annotation | 4 | TYR A 297GLU A 523PRO A 524VAL A 454 | None | 1.22A | 1q13A-2wb7A:undetectable | 1q13A-2wb7A:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xn8 | PUTATIVE CYTOCHROMEP450 125 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | TYR A 208GLU A 408PRO A 407VAL A 167 | None | 1.34A | 1q13A-2xn8A:undetectable | 1q13A-2xn8A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y4l | MANNOSYLGLYCERATESYNTHASE (Rhodothermusmarinus) |
no annotation | 4 | TYR A 207TYR A 122GLU A 254PRO A 256 | EDO A 502 ( 4.5A)EDO A 506 ( 3.7A)NoneNone | 1.37A | 1q13A-2y4lA:undetectable | 1q13A-2y4lA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bxw | CHITINASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
no annotation | 4 | HIS B 306GLU B 292PRO B 293VAL B 333 | None | 1.18A | 1q13A-3bxwB:9.0 | 1q13A-3bxwB:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dcd | GALACTOSE MUTAROTASERELATED ENZYME (Lactobacillusacidophilus) |
PF01263(Aldose_epim) | 4 | TYR A 207GLU A 253PRO A 144VAL A 250 | None | 1.36A | 1q13A-3dcdA:undetectable | 1q13A-3dcdA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dwb | ENDOTHELIN-CONVERTING ENZYME 1 (Homo sapiens) |
PF01431(Peptidase_M13)PF05649(Peptidase_M13_N) | 4 | TYR A 682TYR A 679HIS A 752PRO A 593 | None | 1.42A | 1q13A-3dwbA:undetectable | 1q13A-3dwbA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ekg | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Azotobactervinelandii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TYR A 23HIS A 320GLU A 362PRO A 363 | NoneTLA A 501 (-4.3A)NoneNone | 1.39A | 1q13A-3ekgA:5.5 | 1q13A-3ekgA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fg4 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | TYR A1054HIS A 752PRO A 593VAL A 997 | NoneNoneNoneACY A2203 (-4.5A) | 1.43A | 1q13A-3fg4A:undetectable | 1q13A-3fg4A:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fii | BOTULINUM NEUROTOXINTYPE F (Clostridiumbotulinum) |
PF01742(Peptidase_M27) | 4 | TYR A 349TYR A 345GLU A 265VAL A 242 | None | 1.20A | 1q13A-3fiiA:undetectable | 1q13A-3fiiA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hn7 | UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE (Psychrobacterarcticus) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | TYR A 35HIS A 491PRO A 432VAL A 462 | None | 1.28A | 1q13A-3hn7A:undetectable | 1q13A-3hn7A:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ipc | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN (AMINO ACID) (Agrobacteriumfabrum) |
PF13458(Peripla_BP_6) | 4 | TYR A 345TYR A 333GLU A 273PRO A 272 | None | 1.30A | 1q13A-3ipcA:undetectable | 1q13A-3ipcA:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j1u | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1, SERYLT-RNA SYNTHETASECHIMERA (Mus musculus) |
PF12777(MT) | 4 | TYR A3400GLU A3408PRO A3409VAL A3276 | None | 1.38A | 1q13A-3j1uA:undetectable | 1q13A-3j1uA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4j | TRANSLATIONINITIATION FACTORIF-2 (Thermusthermophilus) |
PF00009(GTP_EFTU)PF04760(IF2_N)PF11987(IF-2) | 4 | TYR A 206GLU A 190PRO A 189VAL A 212 | None | 1.43A | 1q13A-3j4jA:undetectable | 1q13A-3j4jA:21.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ln3 | DIHYDRODIOLDEHYDROGENASE (Mus musculus) |
PF00248(Aldo_ket_red) | 4 | TYR A 24TYR A 55HIS A 117GLU A 226 | MLY A 25 (-3.6A)NAD A 327 ( 4.7A)MRD A 328 ( 3.9A)MLY A 27 ( 3.3A) | 0.89A | 1q13A-3ln3A:50.6 | 1q13A-3ln3A:65.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mi6 | ALPHA-GALACTOSIDASE (Lactobacillusbrevis) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | TYR A 504GLU A 416PRO A 415VAL A 456 | None | 1.40A | 1q13A-3mi6A:9.7 | 1q13A-3mi6A:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mi6 | ALPHA-GALACTOSIDASE (Lactobacillusbrevis) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | TYR A 504GLU A 416PRO A 415VAL A 457 | None | 1.37A | 1q13A-3mi6A:9.7 | 1q13A-3mi6A:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n26 | AMINO ACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Chlamydiapneumoniae) |
PF00497(SBP_bac_3) | 4 | TYR A 41GLU A 186PRO A 187VAL A 192 | ARG A 500 (-3.5A)ARG A 500 (-2.9A)NoneNone | 1.14A | 1q13A-3n26A:undetectable | 1q13A-3n26A:23.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otl | PUTATIVEUNCHARACTERIZEDPROTEIN (Rhizobiumleguminosarum) |
PF08327(AHSA1) | 4 | TYR A 90TYR A 73GLU A 121VAL A 106 | NoneMES A 159 ( 4.9A)NoneNone | 0.91A | 1q13A-3otlA:undetectable | 1q13A-3otlA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oz6 | MITOGEN-ACTIVATEDPROTEIN KINASE 1,SERINE/THREONINEPROTEIN KINASE (Cryptosporidiumparvum) |
PF00069(Pkinase) | 4 | TYR A 116TYR A 113GLU A 341PRO A 338 | None | 1.37A | 1q13A-3oz6A:undetectable | 1q13A-3oz6A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qax | PROBABLE ABCTRANSPORTERARGININE-BINDINGPROTEIN ARTJ (Chlamydiapneumoniae) |
PF00497(SBP_bac_3) | 4 | TYR A 20GLU A 165PRO A 166VAL A 171 | ARG A 600 (-3.4A)ARG A 600 (-3.1A)NoneNone | 1.12A | 1q13A-3qaxA:undetectable | 1q13A-3qaxA:24.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qyj | ALR0039 PROTEIN (Nostoc sp. PCC7120) |
PF00561(Abhydrolase_1) | 4 | TYR A 34HIS A 32PRO A 168VAL A 203 | None | 1.39A | 1q13A-3qyjA:undetectable | 1q13A-3qyjA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sfy | CRYPTOCOCCUSNEOFORMANS PROTEINFARNESYLTRANSFERASEALPHA SUBUNIT (Cryptococcusneoformans) |
PF01239(PPTA) | 4 | TYR A 35TYR A 39HIS A 73PRO A 29 | None | 1.35A | 1q13A-3sfyA:undetectable | 1q13A-3sfyA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsd | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Bacillusanthracis) |
PF00478(IMPDH)PF00571(CBS) | 4 | TYR A 118HIS A 113PRO A 99VAL A 123 | None | 1.41A | 1q13A-3tsdA:10.5 | 1q13A-3tsdA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3txa | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcusagalactiae) |
PF00092(VWA) | 4 | TYR A 272HIS A 381PRO A 542VAL A 538 | None | 1.42A | 1q13A-3txaA:undetectable | 1q13A-3txaA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ueb | PUTATIVEUNCHARACTERIZEDPROTEIN (Thermococcusonnurineus) |
PF11419(DUF3194) | 4 | TYR A 69GLU A 71PRO A 73VAL A 80 | None | 1.42A | 1q13A-3uebA:undetectable | 1q13A-3uebA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uuf | LIP1, SECRETORYLIPASE (FAMILY 3) (Malasseziaglobosa) |
PF01764(Lipase_3) | 4 | TYR A 285HIS A 170GLU A 275VAL A 230 | None | 1.40A | 1q13A-3uufA:undetectable | 1q13A-3uufA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uzb | BRANCHED-CHAIN-AMINO-ACIDAMINOTRANSFERASE (Deinococcusradiodurans) |
PF01063(Aminotran_4) | 4 | TYR A 190HIS A 233GLU A 216VAL A 225 | None | 1.06A | 1q13A-3uzbA:undetectable | 1q13A-3uzbA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vot | L-AMINO ACID LIGASE,BL00235 (Bacilluslicheniformis) |
PF13535(ATP-grasp_4) | 4 | TYR A 339TYR A 404HIS A 394VAL A 358 | None | 1.35A | 1q13A-3votA:undetectable | 1q13A-3votA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wai | MALTOSE-BINDINGPERIPLASMIC PROTEIN,TRANSMEMBRANEOLIGOSACCHARYLTRANSFERASE (Archaeoglobusfulgidus;Escherichiacoli) |
PF13416(SBP_bac_8) | 4 | TYR A 708GLU A 727PRO A 738VAL A 745 | None | 1.40A | 1q13A-3waiA:undetectable | 1q13A-3waiA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3waj | TRANSMEMBRANEOLIGOSACCHARYLTRANSFERASE (Archaeoglobusfulgidus) |
PF02516(STT3) | 4 | TYR A 708GLU A 727PRO A 738VAL A 745 | None | 1.37A | 1q13A-3wajA:undetectable | 1q13A-3wajA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wqy | ALANINE--TRNA LIGASE (Archaeoglobusfulgidus) |
PF01411(tRNA-synt_2c)PF02272(DHHA1)PF07973(tRNA_SAD) | 4 | TYR A 84HIS A 151GLU A 673VAL A 108 | None | 1.29A | 1q13A-3wqyA:undetectable | 1q13A-3wqyA:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b99 | MITOGEN-ACTIVATEDPROTEIN KINASE 7 (Homo sapiens) |
PF00069(Pkinase) | 4 | TYR A 164TYR A 161GLU A 356PRO A 353 | None | 1.26A | 1q13A-4b99A:undetectable | 1q13A-4b99A:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bgd | PRE-MRNA-SPLICINGFACTOR 8 (Saccharomycescerevisiae) |
PF08084(PROCT) | 4 | TYR C2305HIS C2260PRO C2331VAL C2274 | None | 1.37A | 1q13A-4bgdC:undetectable | 1q13A-4bgdC:25.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c0d | CCR4-NOTTRANSCRIPTIONCOMPLEX SUBUNIT 1CCR4-NOTTRANSCRIPTIONCOMPLEX SUBUNIT 3 (Homo sapiens) |
PF04054(Not1)PF04153(NOT2_3_5) | 4 | TYR C 613HIS A1978PRO A2087VAL A2035 | None | 1.34A | 1q13A-4c0dC:undetectable | 1q13A-4c0dC:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cvu | BETA-MANNOSIDASE (Trichodermaharzianum) |
PF00703(Glyco_hydro_2) | 4 | TYR A 573TYR A 575HIS A 628GLU A 594 | None | 1.33A | 1q13A-4cvuA:6.7 | 1q13A-4cvuA:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fnq | ALPHA-GALACTOSIDASEAGAB (Geobacillusstearothermophilus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | TYR A 503GLU A 415PRO A 414VAL A 455 | None | 1.40A | 1q13A-4fnqA:7.4 | 1q13A-4fnqA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g56 | HSL7 PROTEIN (Xenopus laevis) |
PF05185(PRMT5)PF17285(PRMT5_TIM)PF17286(PRMT5_C) | 4 | TYR A 464HIS A 519GLU A 440PRO A 310 | NoneNoneSAH A 701 (-2.5A)None | 1.31A | 1q13A-4g56A:4.2 | 1q13A-4g56A:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gb7 | 6-AMINOHEXANOATE-DIMER HYDROLASE (Bacillusanthracis) |
PF00144(Beta-lactamase) | 4 | TYR A 123TYR A 127GLU A 121VAL A 387 | None | 1.30A | 1q13A-4gb7A:undetectable | 1q13A-4gb7A:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gqb | PROTEIN ARGININEN-METHYLTRANSFERASE5 (Homo sapiens) |
PF05185(PRMT5)PF17285(PRMT5_TIM)PF17286(PRMT5_C) | 4 | TYR A 468HIS A 523GLU A 444PRO A 314 | NoneNone0XU A 701 (-4.3A)None | 1.33A | 1q13A-4gqbA:3.1 | 1q13A-4gqbA:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hb9 | SIMILARITIES WITHPROBABLEMONOOXYGENASE (Photorhabduslaumondii) |
PF01494(FAD_binding_3) | 4 | TYR A 171HIS A 136GLU A 362VAL A 156 | EDO A 509 (-4.0A)NoneNoneNone | 1.39A | 1q13A-4hb9A:undetectable | 1q13A-4hb9A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4le5 | S-ADENOSYLMETHIONINESYNTHETASE (Campylobacterjejuni) |
PF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C) | 4 | TYR A 177TYR A 2GLU A 135PRO A 141 | None | 1.29A | 1q13A-4le5A:undetectable | 1q13A-4le5A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mea | PREDICTED PROTEIN (Acinetobacternosocomialis) |
PF00561(Abhydrolase_1) | 4 | TYR A 193HIS A 206GLU A 307VAL A 300 | None | 1.43A | 1q13A-4meaA:undetectable | 1q13A-4meaA:24.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nv7 | ARYLAMINEN-ACETYLTRANSFERASE (Mesorhizobiumjaponicum) |
PF00797(Acetyltransf_2) | 4 | TYR A 189HIS A 82PRO A 183VAL A 91 | None | 1.43A | 1q13A-4nv7A:undetectable | 1q13A-4nv7A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oby | ARGININE--TRNALIGASE (Escherichiacoli) |
PF00750(tRNA-synt_1d)PF03485(Arg_tRNA_synt_N)PF05746(DALR_1) | 4 | TYR A 323TYR A 261HIS A 158VAL A 116 | NoneNoneARG A 601 (-3.7A)None | 1.11A | 1q13A-4obyA:undetectable | 1q13A-4obyA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbn | NUCLEASE (Salmonellavirus SETP3) |
PF08774(VRR_NUC) | 4 | TYR A 28GLU A 50PRO A 59VAL A 77 | None | 1.43A | 1q13A-4qbnA:undetectable | 1q13A-4qbnA:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qs9 | HEXOKINASE-1 (Arabidopsisthaliana) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 4 | TYR A 240TYR A 241GLU A 93VAL A 112 | None | 1.39A | 1q13A-4qs9A:undetectable | 1q13A-4qs9A:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qtb | MITOGEN-ACTIVATEDPROTEIN KINASE 3 (Homo sapiens) |
PF00069(Pkinase) | 4 | TYR A 148TYR A 145GLU A 339PRO A 336 | NoneEDO A 407 (-3.8A)NoneNone | 1.35A | 1q13A-4qtbA:undetectable | 1q13A-4qtbA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4upi | SULFATASE FAMILYPROTEIN (Ruegeriapomeroyi) |
PF00884(Sulfatase) | 4 | TYR A 65HIS A 495GLU A 375VAL A 444 | None | 1.29A | 1q13A-4upiA:undetectable | 1q13A-4upiA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbd | BSHC (Bacillussubtilis) |
PF10079(BshC) | 4 | TYR A 511HIS A 104GLU A 384VAL A 537 | ADP A 601 (-4.7A)NoneADP A 601 (-3.1A)None | 1.10A | 1q13A-4wbdA:undetectable | 1q13A-4wbdA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd9 | NISIN BIOSYNTHESISPROTEIN NISB (Lactococcuslactis) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 4 | TYR A 442GLU A 682PRO A 613VAL A 408 | None | 1.39A | 1q13A-4wd9A:undetectable | 1q13A-4wd9A:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd9 | NISIN BIOSYNTHESISPROTEIN NISB (Lactococcuslactis) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 4 | TYR A 442GLU A 682PRO A 613VAL A 605 | None | 1.38A | 1q13A-4wd9A:undetectable | 1q13A-4wd9A:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xu4 | UNCHARACTERIZEDPROTEIN (Mycolicibacteriumvanbaalenii) |
no annotation | 4 | TYR A 150HIS A 26PRO A 103VAL A 108 | NoneDDQ A 303 (-4.3A)NoneNone | 1.00A | 1q13A-4xu4A:undetectable | 1q13A-4xu4A:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zsl | MITOGEN-ACTIVATEDPROTEIN KINASE 7 (Homo sapiens) |
PF00069(Pkinase) | 4 | TYR A 164TYR A 161GLU A 356PRO A 353 | None | 1.28A | 1q13A-4zslA:undetectable | 1q13A-4zslA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c8g | PP-BRD20 (Trypanosomabrucei) |
PF00439(Bromodomain) | 4 | TYR A 33TYR A 30GLU A 44PRO A 6 | None | 1.43A | 1q13A-5c8gA:undetectable | 1q13A-5c8gA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dud | YBGJYBGK (Escherichiacoli) |
PF02626(CT_A_B)PF02682(CT_C_D) | 4 | TYR B 7GLU A 181PRO A 256VAL A 233 | None | 1.39A | 1q13A-5dudB:undetectable | 1q13A-5dudB:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f2o | FATTY ACIDO-METHYLTRANSFERASE (Mycobacteriummarinum) |
PF03492(Methyltransf_7) | 4 | TYR A 63GLU A 202PRO A 140VAL A 59 | None | 1.27A | 1q13A-5f2oA:undetectable | 1q13A-5f2oA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hx0 | UNCHARACTERIZEDPROTEIN DFER_1899 (Dyadobacterfermentans) |
PF13088(BNR_2) | 4 | TYR A 365TYR A 381HIS A 54GLU A 262 | ACT A 402 (-4.5A)NoneNoneACT A 402 ( 4.6A) | 1.31A | 1q13A-5hx0A:undetectable | 1q13A-5hx0A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iig | VACUOLAR TRANSPORTERCHAPERONE 4 (Saccharomycescerevisiae) |
PF03105(SPX)PF09359(VTC) | 4 | HIS A 461GLU A 451PRO A 452VAL A 424 | None | 1.29A | 1q13A-5iigA:undetectable | 1q13A-5iigA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kg9 | ANTIBODY RE505-22FAB LIGHT CHAIN (Homo sapiens;Mus musculus) |
no annotation | 4 | TYR L 173HIS L 198GLU L 83PRO L 80 | None | 1.38A | 1q13A-5kg9L:undetectable | 1q13A-5kg9L:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lo9 | CYTOCHROME C (Marichromatiumpurpuratum) |
PF00034(Cytochrom_C)PF13442(Cytochrome_CBB3) | 4 | TYR A 398TYR A 469HIS A 473PRO A 422 | NoneNoneNoneHEC A1004 (-4.0A) | 1.36A | 1q13A-5lo9A:undetectable | 1q13A-5lo9A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ltm | PHENYLALANINEAMMONIA LYASE (Anabaena) |
no annotation | 4 | TYR B 66GLU B 75PRO B 76VAL B 80 | None | 0.96A | 1q13A-5ltmB:undetectable | 1q13A-5ltmB:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5msc | CARBOXYLIC ACIDREDUCTASE (Nocardiaiowensis) |
PF00501(AMP-binding) | 4 | TYR A 441GLU A 499PRO A 459VAL A 497 | None | 1.27A | 1q13A-5mscA:undetectable | 1q13A-5mscA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz2 | RUBISCO SMALLSUBUNIT (Thalassiosiraantarctica) |
no annotation | 4 | TYR I 79GLU I 106PRO I 107VAL I 130 | NoneNoneNoneEDO I 202 ( 4.2A) | 1.39A | 1q13A-5mz2I:undetectable | 1q13A-5mz2I:11.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5no8 | BACCELL_00875 (Bacteroidescellulosilyticus) |
no annotation | 4 | TYR A 634GLU A 576PRO A 573VAL A 568 | None | 0.82A | 1q13A-5no8A:undetectable | 1q13A-5no8A:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opj | RHAMNOGALACTURONANLYASE (Bacteroidesthetaiotaomicron) |
no annotation | 4 | TYR A 646HIS A 642PRO A 338VAL A 394 | None | 1.31A | 1q13A-5opjA:undetectable | 1q13A-5opjA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opq | 3,6-ANHYDRO-D-GALACTOSIDASE (Zobelliagalactanivorans) |
no annotation | 4 | TYR A 492HIS A 316GLU A 494VAL A 242 | None | 1.36A | 1q13A-5opqA:7.5 | 1q13A-5opqA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sy1 | STRA6 (Danio rerio) |
PF14752(RBP_receptor) | 4 | TYR A 200TYR A 150HIS A 145VAL A 78 | None | 1.41A | 1q13A-5sy1A:undetectable | 1q13A-5sy1A:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7a | ACYLOXYACYLHYDROLASE LARGESUBUNIT (Oryctolaguscuniculus) |
no annotation | 4 | TYR B 333TYR B 319HIS B 330PRO B 193 | None | 1.31A | 1q13A-5w7aB:undetectable | 1q13A-5w7aB:13.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7c | ACYLOXYACYLHYDROLASE (Homo sapiens) |
no annotation | 4 | TYR C 334TYR C 320HIS C 331PRO C 194 | None | 1.28A | 1q13A-5w7cC:undetectable | 1q13A-5w7cC:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7d | ACYLOXYACYLHYDROLASE (Mus musculus) |
no annotation | 4 | TYR A 333TYR A 319HIS A 330PRO A 193 | None | 1.33A | 1q13A-5w7dA:undetectable | 1q13A-5w7dA:13.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wfc | HISTONE-LYSINE-N-METHYLTRANSFERASE EZH2,POLYCOMB PROTEINSUZ12 CHIMERA (Chaetomiumthermophilum) |
no annotation | 4 | TYR B 809TYR B 878HIS B 307PRO B 299 | A97 B8009 (-4.7A)A97 B8009 (-4.9A)A97 B8009 (-4.4A)None | 1.40A | 1q13A-5wfcB:undetectable | 1q13A-5wfcB:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wug | BETA-GLUCOSIDASE (Paenibacillusbarengoltzii) |
no annotation | 4 | TYR A 605GLU A 611PRO A 32VAL A 87 | None | 1.11A | 1q13A-5wugA:undetectable | 1q13A-5wugA:11.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxu | RIBOSOMAL PROTEINUS7RIBOSOMAL PROTEINUS9 (Toxoplasmagondii) |
PF00177(Ribosomal_S7)PF00380(Ribosomal_S9) | 4 | TYR Q 84GLU F 58PRO F 55VAL F 37 | None | 1.43A | 1q13A-5xxuQ:undetectable | 1q13A-5xxuQ:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cip | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Moorellathermoacetica) |
no annotation | 4 | TYR A 476HIS A 464GLU A 283PRO A 411 | None | 1.27A | 1q13A-6cipA:undetectable | 1q13A-6cipA:14.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6frl | TRYPTOPHANHALOGENASESUPERFAMILY (Brevundimonassp. BAL3) |
no annotation | 4 | TYR A 399GLU A 346PRO A 347VAL A 268 | None | 1.23A | 1q13A-6frlA:undetectable | 1q13A-6frlA:13.67 |