SIMILAR PATTERNS OF AMINO ACIDS FOR 1PJ7_A_FFOA2887_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhw XYLOSE ISOMERASE

(Actinoplanes
missouriensis) 		PF01261
(AP_endonuc_2) 		3 ASP A  57
THR A  90
GLU A 181
 None
 0.85A 1pj7A-1bhwA:
undetectable		 1pj7A-1bhwA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bqc PROTEIN
(BETA-MANNANASE)

(Thermobifida
fusca) 		PF00150
(Cellulase) 		3 ASP A  87
THR A  89
GLU A 225
 None
 0.86A 1pj7A-1bqcA:
undetectable		 1pj7A-1bqcA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7t BETA-N-ACETYLHEXOSAM
INIDASE

(Serratia
marcescens) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b)
PF03173
(CHB_HEX)
PF03174
(CHB_HEX_C) 		3 ASP A 111
THR A 109
GLU A 405
 None
SO4  A2001 (-3.4A)
None
 0.80A 1pj7A-1c7tA:
0.7		 1pj7A-1c7tA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ed3 CLASS I MAJOR
HISTOCOMPATIBILITY
ANTIGEN RT1-AA

(Rattus
norvegicus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		3 ASP A 198
THR A 200
GLU A 229
 None
 0.80A 1pj7A-1ed3A:
undetectable		 1pj7A-1ed3A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fml RETINOL DEHYDRATASE

(Spodoptera
frugiperda) 		PF00685
(Sulfotransfer_1) 		3 ASP A 113
THR A  34
GLU A  15
 None
 0.73A 1pj7A-1fmlA:
1.9		 1pj7A-1fmlA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2d ATP SULFURYLASE

(Penicillium
chrysogenum) 		PF01583
(APS_kinase)
PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		3 ASP A  43
THR A  84
GLU A 130
 None
 0.69A 1pj7A-1i2dA:
2.3		 1pj7A-1i2dA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ifv PROTEIN LLR18B

(Lupinus luteus) 		PF00407
(Bet_v_1) 		3 ASP A  25
THR A  23
GLU A  75
 None
 0.71A 1pj7A-1ifvA:
undetectable		 1pj7A-1ifvA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jed SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		3 ASP A  44
THR A  85
GLU A 128
 None
 0.67A 1pj7A-1jedA:
undetectable		 1pj7A-1jedA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kjv MATURE ALPHA CHAIN
OF MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS I
ANTIGEN (HEAVY
CHAIN)

(Rattus
norvegicus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		3 ASP A 198
THR A 200
GLU A 229
 None
 0.86A 1pj7A-1kjvA:
undetectable		 1pj7A-1kjvA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ko0 DIAMINOPIMELATE
DECARBOXYLASE

(Escherichia
coli) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		3 ASP A 102
THR A 100
GLU A 268
 None
PLP  A 540 ( 4.5A)
PLP  A 540 (-3.5A)
 0.66A 1pj7A-1ko0A:
undetectable		 1pj7A-1ko0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhc MHC CLASS I ANTIGEN
H2-M3

(Mus musculus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		3 ASP A 198
THR A 200
GLU A 229
 None
 0.81A 1pj7A-1mhcA:
undetectable		 1pj7A-1mhcA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nt4 GLUCOSE-1-PHOSPHATAS
E

(Escherichia
coli) 		PF00328
(His_Phos_2) 		3 ASP A 301
THR A 298
GLU A 149
 None
 0.80A 1pj7A-1nt4A:
undetectable		 1pj7A-1nt4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q3b ENDONUCLEASE VIII

(Escherichia
coli) 		PF01149
(Fapy_DNA_glyco)
PF06827
(zf-FPG_IleRS)
PF06831
(H2TH) 		3 ASP A  61
THR A  63
GLU A  48
 None
 0.82A 1pj7A-1q3bA:
undetectable		 1pj7A-1q3bA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf7 PROTEIN (CATALASE
HPII)

(Escherichia
coli) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 ASP A 597
THR A 268
GLU A 321
 None
 0.85A 1pj7A-1qf7A:
undetectable		 1pj7A-1qf7A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxy METHIONYL
AMINOPEPTIDASE

(Staphylococcus
aureus) 		PF00557
(Peptidase_M24) 		3 ASP A  40
THR A  36
GLU A  73
 None
 0.82A 1pj7A-1qxyA:
undetectable		 1pj7A-1qxyA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6x ATP:SULFATE
ADENYLYLTRANSFERASE

(Saccharomyces
cerevisiae) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		3 ASP A  44
THR A  85
GLU A 128
 None
 0.62A 1pj7A-1r6xA:
2.3		 1pj7A-1r6xA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0b THUA-LIKE PROTEIN

(Geobacillus
stearothermophilus) 		PF06283
(ThuA) 		3 ASP A  19
THR A 201
GLU A 153
 None
None
ZN  A3001 (-3.3A)
 0.80A 1pj7A-1t0bA:
2.1		 1pj7A-1t0bA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmc CLASS I
HISTOCOMPATIBILITY
ANTIGEN (HLA-AW68)

(Homo sapiens) 		PF00129
(MHC_I) 		3 ASP A 122
THR A 134
GLU A 128
 None
 0.82A 1pj7A-1tmcA:
undetectable		 1pj7A-1tmcA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uxi MALATE DEHYDROGENASE

(Chloroflexus
aurantiacus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 ASP A 262
THR A 255
GLU A 138
 None
 0.86A 1pj7A-1uxiA:
6.1		 1pj7A-1uxiA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9d DIAPHANOUS PROTEIN
HOMOLOG 1

(Mus musculus) 		PF02181
(FH2) 		3 ASP A 992
THR A1001
GLU A1134
 None
 0.81A 1pj7A-1v9dA:
undetectable		 1pj7A-1v9dA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8o BACTERIAL SIALIDASE

(Micromonospora
viridifaciens) 		PF00754
(F5_F8_type_C)
PF10633
(NPCBM_assoc)
PF13088
(BNR_2) 		3 ASP A 412
THR A 500
GLU A 642
 None
 0.83A 1pj7A-1w8oA:
undetectable		 1pj7A-1w8oA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wky ENDO-BETA-1,4-MANNAN
ASE

(Bacillus sp.
JAMB-602) 		PF00150
(Cellulase) 		3 ASP A 120
THR A 122
GLU A 253
 None
None
NA  A 505 (-2.8A)
 0.82A 1pj7A-1wkyA:
undetectable		 1pj7A-1wkyA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ylo HYPOTHETICAL PROTEIN
SF2450

(Shigella
flexneri) 		PF05343
(Peptidase_M42) 		3 ASP A 149
THR A 147
GLU A  21
 None
 0.78A 1pj7A-1yloA:
2.2		 1pj7A-1yloA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		3 ASP A 403
THR A 698
GLU A 398
 None
 0.81A 1pj7A-2b5mA:
undetectable		 1pj7A-2b5mA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE

(Sulfurisphaera
tokodaii) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ASP A  45
THR A  76
GLU A 115
 None
 0.71A 1pj7A-2f7lA:
undetectable		 1pj7A-2f7lA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gks BIFUNCTIONAL SAT/APS
KINASE

(Aquifex
aeolicus) 		PF01583
(APS_kinase)
PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		3 ASP A  19
THR A  60
GLU A 103
 None
 0.76A 1pj7A-2gksA:
undetectable		 1pj7A-2gksA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gtx METHIONINE
AMINOPEPTIDASE

(Escherichia
coli) 		PF00557
(Peptidase_M24) 		3 ASP A 253
THR A 255
GLU A 131
 None
 0.82A 1pj7A-2gtxA:
undetectable		 1pj7A-2gtxA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2his CELLULOMONAS FIMI
FAMILY 10
BETA-1,4-GLYCANASE

(Cellulomonas
fimi) 		PF00331
(Glyco_hydro_10) 		3 ASP A 296
THR A 276
GLU A  26
 None
 0.78A 1pj7A-2hisA:
undetectable		 1pj7A-2hisA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5i UPF0249 PROTEIN
EF_3048

(Enterococcus
faecalis) 		PF04794
(YdjC) 		3 ASP A  12
THR A  36
GLU A 209
 None
 0.73A 1pj7A-2i5iA:
undetectable		 1pj7A-2i5iA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j1d DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1

(Homo sapiens) 		PF02181
(FH2) 		3 ASP G 845
THR G 855
GLU G 989
 None
 0.75A 1pj7A-2j1dG:
undetectable		 1pj7A-2j1dG:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ji4 PHOSPHORIBOSYL
PYROPHOSPHATE
SYNTHETASE-ASSOCIATE
D PROTEIN 2

(Homo sapiens) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		3 ASP A 340
THR A 338
GLU A 327
 None
 0.85A 1pj7A-2ji4A:
2.2		 1pj7A-2ji4A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oae DIPEPTIDYL PEPTIDASE
4

(Rattus
norvegicus) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		3 ASP A 375
THR A 399
GLU A 422
 None
 0.86A 1pj7A-2oaeA:
2.0		 1pj7A-2oaeA:
22.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ozu HISTONE
ACETYLTRANSFERASE
MYST3

(Homo sapiens) 		PF01853
(MOZ_SAS) 		3 ASP A 609
THR A 605
GLU A 680
 None
ALY  A 604 ( 3.9A)
None
 0.44A 1pj7A-2ozuA:
undetectable		 1pj7A-2ozuA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2whl BETA-MANNANASE

(Salipaludibacillus
agaradhaerens) 		PF00150
(Cellulase) 		3 ASP A  89
THR A  91
GLU A 222
 None
MAN  A1301 ( 4.4A)
None
 0.76A 1pj7A-2whlA:
undetectable		 1pj7A-2whlA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xka FTSZ/TUBULIN-RELATED
PROTEIN

(Bacillus
thuringiensis) 		PF00091
(Tubulin) 		3 ASP A  97
THR A  93
GLU A 185
 None
 0.56A 1pj7A-2xkaA:
3.3		 1pj7A-2xkaA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z6e DISHEVELED-ASSOCIATE
D ACTIVATOR OF
MORPHOGENESIS 1

(Homo sapiens) 		PF02181
(FH2) 		3 ASP A 845
THR A 855
GLU A 989
 None
 0.84A 1pj7A-2z6eA:
undetectable		 1pj7A-2z6eA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayt PUTATIVE
UNCHARACTERIZED
PROTEIN TTHB071

(Thermus
thermophilus) 		PF01261
(AP_endonuc_2) 		3 ASP A 174
THR A 172
GLU A 144
 None
 0.83A 1pj7A-3aytA:
undetectable		 1pj7A-3aytA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdk D-MANNONATE
DEHYDRATASE

(Streptococcus
suis) 		PF03786
(UxuA) 		3 ASP A 264
THR A 235
GLU A 191
 None
 0.74A 1pj7A-3bdkA:
undetectable		 1pj7A-3bdkA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgu PROTEIN GIANT-LENS

(Drosophila
melanogaster) 		PF11581
(Argos) 		3 ASP A 274
THR A 276
GLU A 373
 None
 0.83A 1pj7A-3cguA:
undetectable		 1pj7A-3cguA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cux MALATE SYNTHASE

(Bacillus
anthracis) 		PF01274
(Malate_synthase) 		3 ASP A 275
THR A 248
GLU A 218
 MG  A   1 (-3.3A)
None
None
 0.81A 1pj7A-3cuxA:
undetectable		 1pj7A-3cuxA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cv3 GLUCURONOSYLTRANSFER
ASE GUMK

(Xanthomonas
campestris) 		no annotation 3 ASP A 180
THR A 178
GLU A 140
 None
 0.73A 1pj7A-3cv3A:
2.8		 1pj7A-3cv3A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e8l SERINE PROTEINASE
INHIBITOR A

(Sagittaria
sagittifolia) 		PF00197
(Kunitz_legume) 		3 ASP C 113
THR C 110
GLU C  99
 None
 0.84A 1pj7A-3e8lC:
undetectable		 1pj7A-3e8lC:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase) 		3 ASP A 229
THR A 188
GLU A 152
 None
 0.75A 1pj7A-3f3zA:
undetectable		 1pj7A-3f3zA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hb0 EYES ABSENT HOMOLOG
2 (DROSOPHILA)

(Homo sapiens) 		PF00702
(Hydrolase) 		3 ASP A 525
THR A 278
GLU A 506
 None
None
MG  A 701 (-3.8A)
 0.87A 1pj7A-3hb0A:
undetectable		 1pj7A-3hb0A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbl NLR FAMILY CARD
DOMAIN-CONTAINING
PROTEIN 4

(Mus musculus) 		no annotation 3 ASP K 544
THR K 540
GLU K 824
 None
 0.52A 1pj7A-3jblK:
undetectable		 1pj7A-3jblK:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jrp FUSION PROTEIN OF
PROTEIN TRANSPORT
PROTEIN SEC13 AND
NUCLEOPORIN NUP145

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		3 ASP A 237
THR A 235
GLU A 283
 None
 0.73A 1pj7A-3jrpA:
undetectable		 1pj7A-3jrpA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jtm FORMATE
DEHYDROGENASE,
MITOCHONDRIAL

(Arabidopsis
thaliana) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 ASP A 221
THR A 196
GLU A 154
 GOL  A 387 (-2.9A)
None
None
 0.76A 1pj7A-3jtmA:
undetectable		 1pj7A-3jtmA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jug BETA-MANNANASE

(Bacillus sp.
N16-5) 		PF00150
(Cellulase) 		3 ASP A 120
THR A 122
GLU A 253
 None
 0.77A 1pj7A-3jugA:
undetectable		 1pj7A-3jugA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksd GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1

(Staphylococcus
aureus) 		no annotation 3 ASP Q 315
THR Q 287
GLU Q  23
 None
 0.56A 1pj7A-3ksdQ:
4.9		 1pj7A-3ksdQ:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lij CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		3 ASP A 265
THR A 224
GLU A 188
 None
 0.79A 1pj7A-3lijA:
undetectable		 1pj7A-3lijA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lkb PROBABLE
BRANCHED-CHAIN AMINO
ACID ABC
TRANSPORTER, AMINO
ACID BINDING PROTEIN

(Thermus
thermophilus) 		PF13458
(Peripla_BP_6) 		3 ASP A 344
THR A 351
GLU A 128
 NA  A 394 (-3.1A)
None
None
 0.83A 1pj7A-3lkbA:
4.5		 1pj7A-3lkbA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3luy PROBABLE CHORISMATE
MUTASE

(Bifidobacterium
adolescentis) 		PF00800
(PDT) 		3 ASP A 255
THR A 253
GLU A  62
 None
 0.82A 1pj7A-3luyA:
undetectable		 1pj7A-3luyA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m4a PUTATIVE TYPE I
TOPOISOMERASE

(Deinococcus
radiodurans) 		PF01028
(Topoisom_I) 		3 ASP A 208
THR A 206
GLU A 221
 None
 0.72A 1pj7A-3m4aA:
undetectable		 1pj7A-3m4aA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mkr COATOMER SUBUNIT
EPSILON

(Bos taurus) 		PF04733
(Coatomer_E) 		3 ASP A 200
THR A 186
GLU A 177
 None
 0.75A 1pj7A-3mkrA:
undetectable		 1pj7A-3mkrA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3obv PROTEIN DIAPHANOUS
HOMOLOG 1

(Mus musculus) 		PF02181
(FH2)
PF06345
(Drf_DAD) 		3 ASP E 992
THR E1001
GLU E1134
 None
 0.80A 1pj7A-3obvE:
undetectable		 1pj7A-3obvE:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t7v METHYLORNITHINE
SYNTHASE PYLB

(Methanosarcina
barkeri) 		PF04055
(Radical_SAM) 		3 ASP A 279
THR A 298
GLU A 205
 MD0  A 993 (-3.6A)
MD0  A 993 (-3.4A)
None
 0.71A 1pj7A-3t7vA:
undetectable		 1pj7A-3t7vA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiw GLYCOSYL HYDROLASE
FAMILY 88

(Pedobacter
heparinus) 		PF07470
(Glyco_hydro_88) 		3 ASP A 116
THR A  74
GLU A 369
 EPE  A 501 (-2.8A)
None
None
 0.69A 1pj7A-3wiwA:
undetectable		 1pj7A-3wiwA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wsu BETA-MANNANASE

(Streptomyces
thermolilacinus) 		PF00150
(Cellulase) 		3 ASP A 137
THR A 139
GLU A 273
 None
None
NA  A 402 (-2.8A)
 0.84A 1pj7A-3wsuA:
undetectable		 1pj7A-3wsuA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x27 CUCUMOPINE SYNTHASE

(Marinactinospora
thermotolerans) 		no annotation 3 ASP A  77
THR A  79
GLU A  70
 None
 0.87A 1pj7A-3x27A:
undetectable		 1pj7A-3x27A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aip FE-REGULATED PROTEIN
B

(Neisseria
meningitidis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ASP A 273
THR A 306
GLU A 283
 None
 0.83A 1pj7A-4aipA:
undetectable		 1pj7A-4aipA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4are COLLAGENASE G

(Hathewaya
histolytica) 		PF01752
(Peptidase_M9)
PF08453
(Peptidase_M9_N) 		3 ASP A 466
THR A 421
GLU A 710
 None
 0.79A 1pj7A-4areA:
2.5		 1pj7A-4areA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgy DNA TOPOISOMERASE
3-ALPHA

(Homo sapiens) 		PF01131
(Topoisom_bac)
PF01751
(Toprim) 		3 ASP A 429
THR A 347
GLU A 520
 None
 0.87A 1pj7A-4cgyA:
undetectable		 1pj7A-4cgyA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME,
C-TERMINAL DOMAIN
PROTEIN

(Paracoccus
denitrificans) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A 327
THR A 300
GLU A 249
 None
 0.80A 1pj7A-4dwdA:
undetectable		 1pj7A-4dwdA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwe UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF15421
(Polysacc_deac_3) 		3 ASP A 431
THR A 433
GLU A 456
 None
 0.84A 1pj7A-4dweA:
undetectable		 1pj7A-4dweA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eys MCCC FAMILY PROTEIN

(Streptococcus
pneumoniae) 		PF02016
(Peptidase_S66) 		3 ASP A 286
THR A 317
GLU A 137
 None
 0.84A 1pj7A-4eysA:
undetectable		 1pj7A-4eysA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fay MICROCOMPARTMENTS
PROTEIN

(Lactobacillus
reuteri) 		PF00936
(BMC) 		3 ASP A  53
THR A  84
GLU A 195
 None
GOL  A 304 ( 3.9A)
GOL  A 303 ( 2.9A)
 0.78A 1pj7A-4fayA:
3.2		 1pj7A-4fayA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fk9 CELLULOSE-BINDING
FAMILY II

(Streptomyces
sp. SirexAA-E) 		PF00150
(Cellulase) 		3 ASP A 137
THR A 139
GLU A 273
 None
 0.86A 1pj7A-4fk9A:
undetectable		 1pj7A-4fk9A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnm E3 ALPHA-ESTERASE-7
CARBOXYLESTERASE

(Lucilia cuprina) 		PF00135
(COesterase) 		3 ASP A 273
THR A 262
GLU A 302
 None
 0.83A 1pj7A-4fnmA:
undetectable		 1pj7A-4fnmA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0m C-PHYCOCYANIN ALPHA
CHAIN
C-PHYCOCYANIN BETA
CHAIN

(Synechococcus
elongatus;
Synechococcus
elongatus) 		PF00502
(Phycobilisome)
PF00502
(Phycobilisome) 		3 ASP B 101
THR B   6
GLU A 109
 None
 0.79A 1pj7A-4h0mB:
undetectable		 1pj7A-4h0mB:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjh PHOSPHOMANNOMUTASE

(Brucella
melitensis) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ASP A 421
THR A 281
GLU A 216
 None
EDO  A 548 (-4.6A)
G6Q  A 544 (-4.3A)
 0.77A 1pj7A-4hjhA:
2.9		 1pj7A-4hjhA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i59 CYCLOHEXYLAMINE
OXIDASE

(Microbacterium
oxydans) 		PF01593
(Amino_oxidase) 		3 ASP A 347
THR A 345
GLU A 187
 None
 0.76A 1pj7A-4i59A:
15.1		 1pj7A-4i59A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i5s PUTATIVE HISTIDINE
KINASE COVS
VICK-LIKE PROTEIN

(Streptococcus
mutans) 		PF00512
(HisKA)
PF00989
(PAS)
PF02518
(HATPase_c) 		3 ASP A 324
THR A 329
GLU A 253
 None
 0.65A 1pj7A-4i5sA:
undetectable		 1pj7A-4i5sA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ida RIPENING-INDUCED
PROTEIN

(Fragaria vesca) 		PF08240
(ADH_N)
PF13602
(ADH_zinc_N_2) 		3 ASP A 214
THR A 195
GLU A 236
 None
 0.80A 1pj7A-4idaA:
3.9		 1pj7A-4idaA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4keg MALTOSE-BINDING
PERIPLASMIC/PALATE
LUNG AND NASAL
EPITHELIUM CLONE
FUSION PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF01273
(LBP_BPI_CETP)
PF13416
(SBP_bac_8) 		3 ASP A  82
THR A  80
GLU A 274
 None
 0.86A 1pj7A-4kegA:
undetectable		 1pj7A-4kegA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyk CYCLIC DI-GMP
PHOSPHODIESTERASE
YAHA

(Escherichia
coli) 		PF00563
(EAL) 		3 ASP A 263
THR A 234
GLU A 164
 None
 0.86A 1pj7A-4lykA:
undetectable		 1pj7A-4lykA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxq D-GLUCURONYL C5
EPIMERASE B

(Danio rerio) 		PF06662
(C5-epim_C) 		3 ASP A 321
THR A 367
GLU A 197
 None
 0.84A 1pj7A-4pxqA:
undetectable		 1pj7A-4pxqA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ql9 ALKYLHYDROPEROXIDE
REDUCTASE SUBUNIT C

(Escherichia
coli) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		3 ASP A  42
THR A  44
GLU A 139
 None
 0.52A 1pj7A-4ql9A:
2.4		 1pj7A-4ql9A:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rm7 ACYL-COA
DEHYDROGENASE

(Slackia
heliotrinireducens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 ASP A 176
THR A 174
GLU A 221
 None
 0.83A 1pj7A-4rm7A:
undetectable		 1pj7A-4rm7A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis) 		no annotation 3 ASP A  12
THR A  73
GLU A 115
 INS  A 301 (-2.8A)
None
None
 0.84A 1pj7A-4xf7A:
5.3		 1pj7A-4xf7A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xia D-XYLOSE ISOMERASE

(Arthrobacter
sp. NRRL B3728) 		PF01261
(AP_endonuc_2) 		3 ASP A  56
THR A  89
GLU A 180
 None
SOR  A 400 (-3.3A)
MG  A 399 ( 2.5A)
 0.88A 1pj7A-4xiaA:
undetectable		 1pj7A-4xiaA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zmh UNCHARACTERIZED
PROTEIN

(Saccharophagus
degradans) 		PF15979
(Glyco_hydro_115) 		3 ASP A 403
THR A 880
GLU A 451
 None
 0.85A 1pj7A-4zmhA:
4.3		 1pj7A-4zmhA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b47 2-OXOACID--FERREDOXI
N OXIDOREDUCTASE
BETA SUBUNIT

(Sulfurisphaera
tokodaii) 		PF02775
(TPP_enzyme_C)
PF12367
(PFO_beta_C) 		3 ASP B 266
THR B 269
GLU B 277
 None
 0.63A 1pj7A-5b47B:
undetectable		 1pj7A-5b47B:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dmh UNCHARACTERIZED
PROTEIN CONSERVED IN
BACTERIA

(Cupriavidus
necator) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		3 ASP A  99
THR A  65
GLU A 348
 None
None
ADP  A 501 (-3.0A)
 0.80A 1pj7A-5dmhA:
2.3		 1pj7A-5dmhA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dx9 TREHALOSE-6-PHOSPHAT
E PHOSPHATASE

(Cryptococcus
neoformans) 		PF02358
(Trehalose_PPase) 		3 ASP A 210
THR A 213
GLU A 180
 MG  A 401 (-2.8A)
None
T6P  A 402 (-2.7A)
 0.75A 1pj7A-5dx9A:
undetectable		 1pj7A-5dx9A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g2v N-ACETYLGLUCOSAMINE-
6-SULFATASE

(Bacteroides
thetaiotaomicron) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 ASP A  38
THR A  40
GLU A 356
 CA  A1521 ( 2.8A)
None
None
 0.81A 1pj7A-5g2vA:
undetectable		 1pj7A-5g2vA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1) 		3 ASP b  85
THR b  62
GLU b 379
 None
 0.79A 1pj7A-5gw5b:
undetectable		 1pj7A-5gw5b:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4k MANGANESE-BINDING
LIPOPROTEIN MNTA

(Listeria
monocytogenes) 		PF01297
(ZnuA) 		3 ASP A 100
THR A  94
GLU A 136
 None
 0.88A 1pj7A-5i4kA:
2.0		 1pj7A-5i4kA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jbg LGP2

(Gallus gallus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF11648
(RIG-I_C-RD) 		3 ASP A 420
THR A 423
GLU A  65
 None
 0.81A 1pj7A-5jbgA:
undetectable		 1pj7A-5jbgA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k59 UNCHARACTERIZED
LEUKOCIDIN-LIKE
PROTEIN 1
UNCHARACTERIZED
LEUKOCIDIN-LIKE
PROTEIN 2

(Staphylococcus
aureus;
Staphylococcus
aureus) 		no annotation
no annotation 		3 ASP D 140
THR D 142
GLU B 139
 None
 0.84A 1pj7A-5k59D:
undetectable		 1pj7A-5k59D:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k7m N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14

(Homo sapiens) 		PF05063
(MT-A70) 		3 ASP B 350
THR B 352
GLU B 192
 None
 0.81A 1pj7A-5k7mB:
undetectable		 1pj7A-5k7mB:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l6e N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14

(Homo sapiens) 		PF05063
(MT-A70) 		3 ASP B 350
THR B 352
GLU B 192
 None
 0.86A 1pj7A-5l6eB:
undetectable		 1pj7A-5l6eB:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9w THEBAINE
6-O-DEMETHYLASE

(Papaver
somniferum) 		no annotation 3 ASP A 116
THR A 119
GLU A  14
 None
None
EDO  A 408 ( 4.2A)
 0.73A 1pj7A-5o9wA:
undetectable		 1pj7A-5o9wA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5olc GALACTONATE
DEHYDRATASE

(Zobellia
galactanivorans) 		no annotation 3 ASP A 339
THR A 342
GLU A  47
 None
 0.51A 1pj7A-5olcA:
2.1		 1pj7A-5olcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5swj PROBABLE ATP
SYNTHASE SPAL/MXIB

(Shigella
flexneri) 		PF00006
(ATP-synt_ab) 		3 ASP A 249
THR A 252
GLU A 307
 None
 0.77A 1pj7A-5swjA:
undetectable		 1pj7A-5swjA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tey N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14

(Homo sapiens) 		PF05063
(MT-A70) 		3 ASP B 350
THR B 352
GLU B 192
 None
UNX  B 406 ( 4.6A)
None
 0.87A 1pj7A-5teyB:
undetectable		 1pj7A-5teyB:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tjf ALLOPHYCOCYANIN
ALPHA SUBUNIT
ALLOPHYCOCYANIN BETA
SUBUNIT

(Gracilaria
chilensis;
Gracilaria
chilensis) 		PF00502
(Phycobilisome)
PF00502
(Phycobilisome) 		3 ASP B 100
THR B   6
GLU A 106
 None
 0.77A 1pj7A-5tjfB:
undetectable		 1pj7A-5tjfB:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x15 PUTATIVE TRANSFERASE

(Streptomyces
coelicolor) 		PF03737
(RraA-like) 		3 ASP A 209
THR A  50
GLU A 235
 None
 0.85A 1pj7A-5x15A:
undetectable		 1pj7A-5x15A:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyb -

(-) 		no annotation 3 ASP A 328
THR A 164
GLU A 132
 None
 0.86A 1pj7A-5xybA:
undetectable		 1pj7A-5xybA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y4j XYLOSE ISOMERASE

(Streptomyces
rubiginosus) 		PF01261
(AP_endonuc_2) 		3 ASP A  57
THR A  90
GLU A 181
 None
XYL  A 402 ( 4.1A)
XYL  A 402 ( 2.4A)
 0.79A 1pj7A-5y4jA:
undetectable		 1pj7A-5y4jA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ys9 ACYL-COENZYME A
OXIDASE 3

(Yarrowia
lipolytica) 		no annotation 3 ASP A  40
THR A  42
GLU A  56
 None
 0.83A 1pj7A-5ys9A:
undetectable		 1pj7A-5ys9A:
undetectable