SIMILAR PATTERNS OF AMINO ACIDS FOR 1P91_B_SAMB2401_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d9z | EXCINUCLEASE UVRABCCOMPONENT UVRB ([Bacillus]caldotenax) |
PF00271(Helicase_C)PF04851(ResIII)PF12344(UvrB) | 5 | GLY A 44GLY A 42ILE A 411LEU A 401THR A 36 | ATP A 700 (-3.0A)ATP A 700 (-3.4A)NoneNoneNone | 1.07A | 1p91B-1d9zA:2.3 | 1p91B-1d9zA:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj3 | ADENYLOSUCCINATESYNTHETASE (Triticumaestivum) |
PF00709(Adenylsucc_synt) | 5 | TYR A 429GLY A 435GLY A 433LEU A 17PRO A 42 | NoneNoneGDP A 500 (-3.2A)NoneNone | 0.91A | 1p91B-1dj3A:undetectable | 1p91B-1dj3A:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nff | PUTATIVEOXIDOREDUCTASERV2002 (Mycobacteriumtuberculosis) |
PF13561(adh_short_C2) | 5 | ARG A 177GLY A 175GLY A 172ILE A 135LEU A 215 | None | 0.98A | 1p91B-1nffA:5.0 | 1p91B-1nffA:23.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p91 | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE A (Escherichiacoli) |
PF13847(Methyltransf_31) | 8 | TYR A 67GLY A 95GLY A 97TYR A 98TYR A 99LEU A 184THR A 234PRO A 235 | NoneSAM A1401 (-3.4A)SAM A1401 (-3.3A)NoneSAM A1401 (-4.4A)SAM A1401 (-4.6A)NoneNone | 0.64A | 1p91B-1p91A:37.8 | 1p91B-1p91A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p91 | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE A (Escherichiacoli) |
PF13847(Methyltransf_31) | 5 | TYR A 67LEU A 70GLY A 93TYR A 99LEU A 184 | NoneNoneNoneSAM A1401 (-4.4A)SAM A1401 (-4.6A) | 1.00A | 1p91B-1p91A:37.8 | 1p91B-1p91A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p91 | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE A (Escherichiacoli) |
PF13847(Methyltransf_31) | 8 | TYR A 67LEU A 70GLY A 95GLY A 97TYR A 98TYR A 99ILE A 155LEU A 184 | NoneNoneSAM A1401 (-3.4A)SAM A1401 (-3.3A)NoneSAM A1401 (-4.4A)SAM A1401 (-4.2A)SAM A1401 (-4.6A) | 0.41A | 1p91B-1p91A:37.8 | 1p91B-1p91A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p91 | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE A (Escherichiacoli) |
PF13847(Methyltransf_31) | 8 | TYR A 67LEU A 70GLY A 95GLY A 97TYR A 98TYR A 99LEU A 184THR A 234 | NoneNoneSAM A1401 (-3.4A)SAM A1401 (-3.3A)NoneSAM A1401 (-4.4A)SAM A1401 (-4.6A)None | 0.61A | 1p91B-1p91A:37.8 | 1p91B-1p91A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1p91 | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE A (Escherichiacoli) |
PF13847(Methyltransf_31) | 5 | TYR A 67LEU A 70GLY A 95TYR A 99ILE A 155 | NoneNoneSAM A1401 (-3.4A)SAM A1401 (-4.4A)SAM A1401 (-4.2A) | 1.09A | 1p91B-1p91A:37.8 | 1p91B-1p91A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ryy | ALPHA-AMINO ACIDESTER HYDROLASE (Acetobacterpasteurianus) |
PF02129(Peptidase_S15)PF08530(PepX_C) | 5 | LEU A 532GLY A 466GLY A 653ILE A 650LEU A 587 | None | 1.03A | 1p91B-1ryyA:undetectable | 1p91B-1ryyA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t3d | SERINEACETYLTRANSFERASE (Escherichiacoli) |
PF00132(Hexapep)PF06426(SATase_N) | 5 | LEU A 182GLY A 217GLY A 215ILE A 202LEU A 111 | None | 1.02A | 1p91B-1t3dA:undetectable | 1p91B-1t3dA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tmo | TRIMETHYLAMINEN-OXIDE REDUCTASE (Shewanellamassilia) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | LEU A 185GLY A 357GLY A 359ILE A 183LEU A 194 | None | 1.03A | 1p91B-1tmoA:undetectable | 1p91B-1tmoA:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ton | TONIN (Rattus rattus) |
PF00089(Trypsin) | 5 | LEU A 67GLY A 193GLY A 142ILE A 34LEU A 108 | None | 1.10A | 1p91B-1tonA:undetectable | 1p91B-1tonA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tyd | TYROSYL-TRNASYNTHETASE (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 5 | LEU E 44GLY E 71GLY E 74ILE E 101LEU E 109 | None | 1.09A | 1p91B-1tydE:2.4 | 1p91B-1tydE:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uek | 4-(CYTIDINE5'-DIPHOSPHO)-2C-METHYL-D-ERYTHRITOLKINASE (Thermusthermophilus) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | LEU A 265GLY A 232GLY A 90LEU A 187PRO A 182 | None | 1.04A | 1p91B-1uekA:undetectable | 1p91B-1uekA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wwk | PHOSPHOGLYCERATEDEHYDROGENASE (Pyrococcushorikoshii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 187GLY A 151GLY A 148ILE A 145THR A 141 | NoneNoneNAD A1001 (-3.2A)NoneNone | 1.08A | 1p91B-1wwkA:6.2 | 1p91B-1wwkA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wza | ALPHA-AMYLASE A (Halothermothrixorenii) |
PF00128(Alpha-amylase) | 5 | TYR A 62LEU A 63GLY A 51ILE A 37LEU A 418 | NoneNone CA A 601 ( 4.9A)NoneNone | 1.09A | 1p91B-1wzaA:undetectable | 1p91B-1wzaA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zov | MONOMERIC SARCOSINEOXIDASE (Bacillus sp.NS-129) |
PF01266(DAO) | 5 | LEU A 71GLY A 15GLY A 19TYR A 20TYR A 21 | None | 1.08A | 1p91B-1zovA:undetectable | 1p91B-1zovA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zud | ADENYLYLTRANSFERASETHIF (Escherichiacoli) |
PF00899(ThiF) | 5 | LEU 1 107GLY 1 40GLY 1 37ILE 1 34THR 1 54 | None | 1.10A | 1p91B-1zud1:3.8 | 1p91B-1zud1:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2avt | DNA POLYMERASE IIIBETA SUBUNIT (Streptococcuspyogenes) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | LEU A 292GLY A 322ILE A 299LEU A 338THR A 268 | None | 1.10A | 1p91B-2avtA:undetectable | 1p91B-2avtA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ayn | UBIQUITINCARBOXYL-TERMINALHYDROLASE 14 (Homo sapiens) |
PF00443(UCH) | 5 | LEU A 285GLY A 480TYR A 479ILE A 325THR A 424 | None | 1.09A | 1p91B-2aynA:undetectable | 1p91B-2aynA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bqp | PROTEIN (PEA LECTIN) (Pisum sativum) |
PF00139(Lectin_legB) | 5 | GLY A 102GLY A 97TYR A 100ILE A 144THR A 112 | None | 1.12A | 1p91B-2bqpA:undetectable | 1p91B-2bqpA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dbr | GLYOXYLATE REDUCTASE (Pyrococcushorikoshii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | LEU A 198GLY A 162GLY A 159ILE A 156THR A 152 | NoneNoneNAP A 401 (-3.5A)NoneNone | 1.09A | 1p91B-2dbrA:5.9 | 1p91B-2dbrA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dh3 | 4F2 CELL-SURFACEANTIGEN HEAVY CHAIN (Homo sapiens) |
PF00128(Alpha-amylase) | 5 | TYR A 149LEU A 150GLY A 138ILE A 126LEU A 419 | None | 1.04A | 1p91B-2dh3A:undetectable | 1p91B-2dh3A:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g3n | ALPHA-GLUCOSIDASE (Sulfolobussolfataricus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 5 | LEU A 556GLY A 583ILE A 600LEU A 533THR A 571 | None | 1.10A | 1p91B-2g3nA:undetectable | 1p91B-2g3nA:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gjn | HYPOTHETICAL PROTEINPA1024 (Pseudomonasaeruginosa) |
PF03060(NMO) | 5 | LEU A 187GLY A 21GLY A 201ILE A 18PRO A 174 | NoneFMN A1904 (-4.0A)FMN A1904 (-3.3A)NoneNone | 0.97A | 1p91B-2gjnA:undetectable | 1p91B-2gjnA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h0b | NEUREXIN-1-ALPHA (Bos taurus) |
PF02210(Laminin_G_2) | 5 | GLY A 349GLY A 347ILE A 344LEU A 320PRO A 436 | None CA A1000 ( 4.4A)NoneNoneNone | 1.02A | 1p91B-2h0bA:undetectable | 1p91B-2h0bA:23.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h3g | BIOSYNTHETIC PROTEIN (Bacillusanthracis) |
PF03309(Pan_kinase) | 5 | LEU X 223GLY X 191GLY X 195TYR X 196ILE X 173 | None | 1.09A | 1p91B-2h3gX:undetectable | 1p91B-2h3gX:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnz | REVERSETRANSCRIPTASE/RIBONUCLEASE H (Humanimmunodeficiencyvirus 1) |
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb) | 5 | LEU A 368GLY A 352TYR A 354ILE A 329THR A 386 | None | 0.84A | 1p91B-2hnzA:undetectable | 1p91B-2hnzA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iut | DNA TRANSLOCASE FTSK (Pseudomonasaeruginosa) |
PF01580(FtsK_SpoIIIE) | 5 | LEU A 462GLY A 676GLY A 471ILE A 650TYR A 680 | NoneAGS A1723 (-3.6A)AGS A1723 (-3.1A)NoneNone | 1.04A | 1p91B-2iutA:2.5 | 1p91B-2iutA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kbf | ATP-DEPENDENT RNAHELICASE DBP5 (Saccharomycescerevisiae) |
PF00271(Helicase_C) | 5 | TYR A 325LEU A 324GLY A 434ILE A 437LEU A 350 | None | 1.11A | 1p91B-2kbfA:undetectable | 1p91B-2kbfA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mhf | UNCHARACTERIZEDPROTEIN (Danio rerio) |
PF00027(cNMP_binding) | 5 | GLY A 70GLY A 68ILE A 73TYR A 48THR A 28 | None | 1.02A | 1p91B-2mhfA:undetectable | 1p91B-2mhfA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vii | PSP OPERONTRANSCRIPTIONALACTIVATOR (Escherichiacoli) |
PF00158(Sigma54_activat) | 5 | LEU A 229TYR A 220ILE A 186LEU A 247THR A 210 | None | 1.01A | 1p91B-2viiA:undetectable | 1p91B-2viiA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x5f | ASPARTATE_TYROSINE_PHENYLALANINEPYRIDOXAL-5'PHOSPHATE-DEPENDENTAMINOTRANSFERASE (Staphylococcusaureus) |
PF00155(Aminotran_1_2) | 5 | GLY A 146TYR A 148ILE A 192THR A 203PRO A 204 | None | 0.96A | 1p91B-2x5fA:2.9 | 1p91B-2x5fA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yet | GH61 ISOZYME A (Thermoascusaurantiacus) |
PF03443(Glyco_hydro_61) | 5 | LEU A 181GLY A 187GLY A 185ILE A 145LEU A 109 | None | 1.09A | 1p91B-2yetA:undetectable | 1p91B-2yetA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yfn | ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK ([Ruminococcus]gnavus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 5 | TYR A 150LEU A 14GLY A 113ILE A 3LEU A 31 | None | 1.11A | 1p91B-2yfnA:undetectable | 1p91B-2yfnA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yjv | REGULATOR OFRIBONUCLEASEACTIVITY A (Escherichiacoli) |
PF03737(RraA-like) | 5 | LEU A 51GLY A 34GLY A 58ILE A 37LEU A 73 | None | 1.07A | 1p91B-2yjvA:undetectable | 1p91B-2yjvA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yw9 | ENOYL-[ACYL CARRIERPROTEIN] REDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 5 | ARG A 184GLY A 182GLY A 179ILE A 142LEU A 229 | None | 0.98A | 1p91B-2yw9A:4.5 | 1p91B-2yw9A:25.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ze5 | ISOPENTENYLTRANSFERASE (Agrobacteriumtumefaciens) |
PF01745(IPT) | 5 | TYR A 211GLY A 97GLY A 8LEU A 152THR A 43 | None | 0.89A | 1p91B-2ze5A:undetectable | 1p91B-2ze5A:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aih | PROTEIN OS-9 (Homo sapiens) |
PF07915(PRKCSH) | 5 | GLY A 178GLY A 176TYR A 175LEU A 112THR A 119 | None | 1.12A | 1p91B-3aihA:undetectable | 1p91B-3aihA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b74 | UNCHARACTERIZEDPROTEIN YKL091C (Saccharomycescerevisiae) |
PF00650(CRAL_TRIO)PF03765(CRAL_TRIO_N) | 5 | TYR A 195TYR A 137ILE A 131TYR A 109LEU A 149 | PEE A 311 (-4.0A)PEE A 311 (-3.8A)PEE A 311 ( 4.4A)PEE A 311 ( 4.8A)None | 1.13A | 1p91B-3b74A:undetectable | 1p91B-3b74A:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bop | BETA-NEUREXIN 2D4 (Mus musculus) |
PF02210(Laminin_G_2) | 5 | LEU A 241GLY A 95GLY A 92ILE A 98LEU A 115 | None | 1.12A | 1p91B-3bopA:undetectable | 1p91B-3bopA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c8f | PYRUVATEFORMATE-LYASE1-ACTIVATING ENZYME (Escherichiacoli) |
PF04055(Radical_SAM)PF13353(Fer4_12) | 5 | LEU A 183GLY A 240TYR A 239ILE A 196THR A 228 | None | 1.04A | 1p91B-3c8fA:undetectable | 1p91B-3c8fA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e73 | LANC-LIKE PROTEIN 1 (Homo sapiens) |
PF05147(LANC_like) | 5 | ARG A 155LEU A 228GLY A 154GLY A 157ILE A 224 | None | 1.09A | 1p91B-3e73A:undetectable | 1p91B-3e73A:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f7o | SERINE PROTEASE (Purpureocilliumlilacinum) |
PF00082(Peptidase_S8) | 5 | GLY A 235GLY A 237TYR A 239ILE A 15THR A 84 | None | 1.12A | 1p91B-3f7oA:undetectable | 1p91B-3f7oA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3few | COLICIN S4 (Escherichiacoli) |
PF01024(Colicin) | 5 | GLY X 104GLY X 92TYR X 91ILE X 107LEU X 228 | None | 1.10A | 1p91B-3fewX:undetectable | 1p91B-3fewX:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fxi | TOLL-LIKE RECEPTOR 4 (Homo sapiens) |
PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 315GLY A 343GLY A 363ILE A 320LEU A 350 | None | 1.04A | 1p91B-3fxiA:undetectable | 1p91B-3fxiA:17.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gb0 | PEPTIDASE T (Bacillus cereus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | GLY A 167GLY A 340TYR A 341ILE A 344LEU A 144 | None | 1.10A | 1p91B-3gb0A:undetectable | 1p91B-3gb0A:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gvd | SERINEACETYLTRANSFERASE (Yersinia pestis) |
PF00132(Hexapep)PF06426(SATase_N) | 5 | LEU A 182GLY A 217GLY A 215ILE A 202LEU A 111 | None | 0.98A | 1p91B-3gvdA:undetectable | 1p91B-3gvdA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h09 | IMMUNOGLOBULIN A1PROTEASE (Haemophilusinfluenzae) |
PF02395(Peptidase_S6)PF03212(Pertactin) | 5 | TYR A 520GLY A 546GLY A 660ILE A 543THR A 175 | None | 1.04A | 1p91B-3h09A:undetectable | 1p91B-3h09A:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h2d | CHEC-LIKESUPERFAMILY PROTEIN (Shewanellaoneidensis) |
PF13690(CheX) | 5 | GLY A 123GLY A 121ILE A 126LEU A 13PRO A 138 | None | 1.10A | 1p91B-3h2dA:undetectable | 1p91B-3h2dA:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjv | MALONYL COA-ACYLCARRIER PROTEINTRANSACYLASE (Vibrio cholerae) |
PF00698(Acyl_transf_1) | 5 | TYR A 101GLY A 108ILE A 248LEU A 217THR A 220 | None | 1.02A | 1p91B-3hjvA:undetectable | 1p91B-3hjvA:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hlm | ASPARTATEAMINOTRANSFERASE,MITOCHONDRIAL (Mus musculus) |
PF00155(Aminotran_1_2) | 5 | LEU A 358GLY A 218GLY A 379ILE A 374LEU A 394 | None | 1.04A | 1p91B-3hlmA:3.2 | 1p91B-3hlmA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hrp | UNCHARACTERIZEDPROTEIN (Bacteroidesthetaiotaomicron) |
PF01833(TIG) | 5 | LEU A 254GLY A 235ILE A 209THR A 229PRO A 228 | None | 1.06A | 1p91B-3hrpA:undetectable | 1p91B-3hrpA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hyv | SULFIDE-QUINONEREDUCTASE (Aquifexaeolicus) |
PF07992(Pyr_redox_2) | 5 | GLY A 13GLY A 11ILE A 398LEU A 407PRO A 415 | FAD A 441 (-3.4A)FAD A 441 (-3.3A)NoneLMT A 600 ( 4.9A)None | 0.99A | 1p91B-3hyvA:3.0 | 1p91B-3hyvA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibx | PUTATIVE THIAMINASEII (Helicobacterpylori) |
PF03070(TENA_THI-4) | 5 | TYR A 165GLY A 26GLY A 28ILE A 142LEU A 48 | None | 1.11A | 1p91B-3ibxA:undetectable | 1p91B-3ibxA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kcx | HYPOXIA-INDUCIBLEFACTOR 1-ALPHAINHIBITOR (Homo sapiens) |
PF13621(Cupin_8) | 5 | LEU A 187GLY A 266GLY A 268ILE A 291THR A 196 | NoneNoneNoneNoneCQL A 1 (-3.8A) | 1.05A | 1p91B-3kcxA:undetectable | 1p91B-3kcxA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kw3 | ALANINE RACEMASE (Bartonellahenselae) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 5 | GLY A 54GLY A 52TYR A 51TYR A 232ILE A 26 | NoneNoneLLP A 47 ( 4.6A)NoneNone | 0.91A | 1p91B-3kw3A:undetectable | 1p91B-3kw3A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lg5 | EPI-ISOZIZAENESYNTHASE (Streptomycescoelicolor) |
no annotation | 6 | LEU A 206GLY A 75TYR A 76TYR A 77ILE A 88TYR A 91 | None | 1.11A | 1p91B-3lg5A:undetectable | 1p91B-3lg5A:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3poy | NEUREXIN-1-ALPHA (Bos taurus) |
PF00008(EGF)PF02210(Laminin_G_2) | 5 | GLY A 365GLY A 363ILE A 360LEU A 336PRO A 452 | None | 1.12A | 1p91B-3poyA:undetectable | 1p91B-3poyA:14.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rgq | PROTEIN-TYROSINEPHOSPHATASEMITOCHONDRIAL 1 (Mus musculus) |
PF00782(DSPc) | 5 | LEU A 215GLY A 116GLY A 203ILE A 109LEU A 187 | NoneNone5P5 A 300 (-3.8A)NoneNone | 1.11A | 1p91B-3rgqA:undetectable | 1p91B-3rgqA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tcr | MOLYBDOPTERINBIOSYNTHESIS PROTEIN (Mycobacteroidesabscessus) |
PF00994(MoCF_biosynth) | 5 | ARG A 119LEU A 162GLY A 131GLY A 122ILE A 148 | None | 1.11A | 1p91B-3tcrA:undetectable | 1p91B-3tcrA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tzq | SHORT-CHAIN TYPEDEHYDROGENASE/REDUCTASE (Mycobacteriummarinum) |
no annotation | 5 | ARG B 179GLY B 177GLY B 174ILE B 137LEU B 223 | None | 1.09A | 1p91B-3tzqB:4.9 | 1p91B-3tzqB:24.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpx | LEUCINEDEHYDROGENASE (Sporosarcinapsychrophila) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | LEU A 106GLY A 77GLY A 37ILE A 31THR A 43 | None | 0.96A | 1p91B-3vpxA:4.9 | 1p91B-3vpxA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxy | PUTATIVEUNCHARACTERIZEDPROTEIN CSYB (Aspergillusoryzae) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 5 | LEU A 372GLY A 154GLY A 376ILE A 349LEU A 222 | None | 0.95A | 1p91B-3wxyA:undetectable | 1p91B-3wxyA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wzf | ASPARTATEAMINOTRANSFERASE,CYTOPLASMIC (Homo sapiens) |
PF00155(Aminotran_1_2) | 5 | LEU A 337GLY A 197GLY A 358ILE A 353LEU A 373 | None | 1.07A | 1p91B-3wzfA:3.2 | 1p91B-3wzfA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuq | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07952(Toxin_trans) | 5 | LEU A 119GLY A 241GLY A 186LEU A 546PRO A 25 | None | 1.10A | 1p91B-3zuqA:undetectable | 1p91B-3zuqA:13.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ain | GLYCINE BETAINETRANSPORTER BETP (Corynebacteriumglutamicum) |
PF02028(BCCT) | 5 | GLY A 128GLY A 391ILE A 394LEU A 536PRO A 223 | None | 1.04A | 1p91B-4ainA:undetectable | 1p91B-4ainA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ber | PHOSPHOCHOLINETRANSFERASE ANKX (Legionellapneumophila) |
PF02661(Fic)PF12796(Ank_2) | 5 | LEU A 76GLY A 236TYR A 225ILE A 80LEU A 8 | NoneC5P A1000 (-3.3A)NoneNoneNone | 1.09A | 1p91B-4berA:undetectable | 1p91B-4berA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxs | VENOM PROTHROMBINACTIVATORPSEUTARIN-CNON-CATALYTICSUBUNIT (Pseudonajatextilis) |
PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 5 | LEU V1329GLY V1282GLY V1278ILE V1289THR V1315 | None | 1.08A | 1p91B-4bxsV:undetectable | 1p91B-4bxsV:10.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d7u | ENDOGLUCANASE II (Neurosporacrassa) |
PF03443(Glyco_hydro_61) | 5 | GLY A 213GLY A 205TYR A 204ILE A 201LEU A 151 | None | 1.08A | 1p91B-4d7uA:undetectable | 1p91B-4d7uA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e8d | GLYCOSYL HYDROLASE,FAMILY 35 (Streptococcuspneumoniae) |
PF01301(Glyco_hydro_35) | 5 | LEU A 364GLY A 537ILE A 495LEU A 446THR A 571 | None | 1.01A | 1p91B-4e8dA:undetectable | 1p91B-4e8dA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eff | AROMATIC-AMINO-ACIDAMINOTRANSFERASE (Burkholderiapseudomallei) |
PF00155(Aminotran_1_2) | 5 | LEU A 327GLY A 188GLY A 348ILE A 343LEU A 363 | None | 1.02A | 1p91B-4effA:undetectable | 1p91B-4effA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f1n | KPAGO (Vanderwaltozymapolyspora) |
PF02171(Piwi) | 5 | LEU A 398GLY A 480GLY A 249TYR A 402ILE A 401 | None | 1.07A | 1p91B-4f1nA:undetectable | 1p91B-4f1nA:11.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h7o | SERINEACETYLTRANSFERASE (Vibrio cholerae) |
PF00132(Hexapep)PF06426(SATase_N) | 5 | LEU A 182GLY A 217GLY A 215ILE A 202LEU A 111 | None | 1.01A | 1p91B-4h7oA:undetectable | 1p91B-4h7oA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hzu | PREDICTED MEMBRANEPROTEINENERGY-COUPLINGFACTOR TRANSPORTERTRANSMEMBRANEPROTEIN ECFT (Lactobacillusbrevis;Lactobacillusbrevis) |
PF07155(ECF-ribofla_trS)PF02361(CbiQ) | 5 | LEU T 171GLY S 60GLY S 64LEU T 219THR S 10 | None | 1.03A | 1p91B-4hzuT:undetectable | 1p91B-4hzuT:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jge | RED FLUORESCENTPROTEIN BLFP-R5 (Branchiostomalanceolatum) |
PF01353(GFP) | 5 | TYR A 75GLY A 179GLY A 82ILE A 182THR A 174 | None | 1.05A | 1p91B-4jgeA:undetectable | 1p91B-4jgeA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3j | HEPATOCYTE GROWTHFACTOR BETA CHAIN (Homo sapiens) |
PF01403(Sema)PF01437(PSI) | 5 | ARG B 521LEU B 481GLY B 517GLY B 519ILE B 513 | None | 1.03A | 1p91B-4k3jB:undetectable | 1p91B-4k3jB:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kt1 | LEUCINE-RICHREPEAT-CONTAININGG-PROTEIN COUPLEDRECEPTOR 4 (Homo sapiens) |
PF01462(LRRNT)PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 62GLY A 47GLY A 45LEU A 101PRO A 73 | NoneNAG A 601 (-4.2A)NoneNoneNone | 0.97A | 1p91B-4kt1A:undetectable | 1p91B-4kt1A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ozx | ALGINATE LYASE (Klebsiellapneumoniae) |
PF08787(Alginate_lyase2) | 5 | GLY A 156TYR A 174ILE A 159TYR A 280THR A 90 | None | 1.04A | 1p91B-4ozxA:undetectable | 1p91B-4ozxA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r1i | AMINOBENZOYL-GLUTAMATE TRANSPORTER (Neisseriagonorrhoeae) |
PF03806(ABG_transport) | 5 | TYR A 234LEU A 231GLY A 139GLY A 178PRO A 127 | None | 1.08A | 1p91B-4r1iA:undetectable | 1p91B-4r1iA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rv3 | 1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE (Staphylococcusaureus) |
PF00388(PI-PLC-X) | 5 | LEU A 100GLY A 60ILE A 108THR A 153PRO A 152 | None | 1.07A | 1p91B-4rv3A:undetectable | 1p91B-4rv3A:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udr | GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE (Methylovorussp. MP688) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | LEU A 269GLY A 463TYR A 89ILE A 73THR A 376 | None | 1.12A | 1p91B-4udrA:undetectable | 1p91B-4udrA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w5k | ASPARTATEAMINOTRANSFERASE,MITOCHONDRIAL (Trypanosomabrucei) |
PF00155(Aminotran_1_2) | 5 | LEU A 316GLY A 176GLY A 337ILE A 332LEU A 352 | None | 1.11A | 1p91B-4w5kA:2.5 | 1p91B-4w5kA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zr5 | NEPRILYSIN (Oryctolaguscuniculus) |
PF01431(Peptidase_M13)PF05649(Peptidase_M13_N) | 5 | GLY A 654GLY A 656TYR A 659LEU A 69PRO A 563 | None | 1.10A | 1p91B-4zr5A:undetectable | 1p91B-4zr5A:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6a | PREDICTED ATPASE OFTHE ABC CLASS (Vibriovulnificus) |
PF09818(ABC_ATPase) | 5 | LEU A 366GLY A 387GLY A 389TYR A 391ILE A 383 | None | 1.08A | 1p91B-5d6aA:undetectable | 1p91B-5d6aA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e25 | BRANCHED-CHAINAMINOTRANSFERASE (Geoglobusacetivorans) |
PF01063(Aminotran_4) | 5 | TYR A 238LEU A 237GLY A 266GLY A 264ILE A 243 | None | 1.04A | 1p91B-5e25A:undetectable | 1p91B-5e25A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eo7 | PREDICTED PROTEIN (Aspergillusoryzae) |
PF07938(Fungal_lectin) | 5 | TYR A 139GLY A 162TYR A 128ILE A 112THR A 132 | None | 1.12A | 1p91B-5eo7A:undetectable | 1p91B-5eo7A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h68 | CHROMOSOME PARTITIONPROTEIN SMC (Geobacillusstearothermophilus) |
PF02463(SMC_N) | 5 | TYR A1131LEU A1123GLY A1049GLY A1053LEU A1116 | None | 0.99A | 1p91B-5h68A:undetectable | 1p91B-5h68A:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j1d | PHOSPHATE BINDINGPROTEIN (Stenotrophomonasmaltophilia) |
PF12849(PBP_like_2) | 5 | GLY A 325GLY A 315TYR A 314ILE A 23LEU A 11 | NoneNoneNoneNonePO4 A 401 (-4.1A) | 1.07A | 1p91B-5j1dA:undetectable | 1p91B-5j1dA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kkg | ANCMT E72A (syntheticconstruct) |
PF04587(ADP_PFK_GK) | 5 | LEU A 106GLY A 96ILE A 102LEU A 382THR A 369 | None | 1.11A | 1p91B-5kkgA:3.1 | 1p91B-5kkgA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oc1 | ARYL-ALCOHOL OXIDASE (Pleurotuseryngii) |
no annotation | 5 | LEU A 316GLY A 70TYR A 71ILE A 493TYR A 492 | None | 1.12A | 1p91B-5oc1A:undetectable | 1p91B-5oc1A:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5us1 | AMINOGLYCOSIDE2'-N-ACETYLTRANSFERASE (Providenciastuartii) |
PF13673(Acetyltransf_10) | 5 | GLY A 111GLY A 155TYR A 123LEU A 25THR A 41 | None | 1.11A | 1p91B-5us1A:undetectable | 1p91B-5us1A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v0s | PREPHENATEDEHYDROGENASE (Bacillusanthracis) |
PF01842(ACT) | 5 | LEU A 320GLY A 345ILE A 339LEU A 367THR A 374 | None | 0.99A | 1p91B-5v0sA:undetectable | 1p91B-5v0sA:14.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w8o | HOMOSERINEO-ACETYLTRANSFERASE (Mycolicibacteriumhassiacum) |
PF00561(Abhydrolase_1) | 5 | GLY A 216GLY A 214TYR A 213TYR A 212LEU A 273 | None | 1.04A | 1p91B-5w8oA:undetectable | 1p91B-5w8oA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w95 | CONSERVED MEMBRANEPROTEIN OFUNCHARACTERISEDFUNCTION (Mycobacteriumtuberculosis) |
no annotation | 5 | LEU A 290GLY A 177GLY A 82ILE A 270THR A 244 | 1PE A 401 (-4.4A)NoneNone1PE A 401 (-4.3A)None | 1.06A | 1p91B-5w95A:undetectable | 1p91B-5w95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xkt | UREASE ACCESSORYPROTEIN UREG (Klebsiellapneumoniae) |
no annotation | 5 | LEU A 110GLY A 19GLY A 17ILE A 126THR A 122 | NoneGNP A 301 (-3.3A)GNP A 301 (-3.3A)NoneNone | 1.13A | 1p91B-5xktA:undetectable | 1p91B-5xktA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | RIBOSOMAL PROTEINS3, PUTATIVE (Trichomonasvaginalis) |
PF00189(Ribosomal_S3_C)PF07650(KH_2) | 5 | LEU D 67GLY D 36GLY D 34ILE D 89LEU D 85 | None | 0.94A | 1p91B-5xyiD:undetectable | 1p91B-5xyiD:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yo8 | TETRAPRENYL-BETA-CURCUMENE SYNTHASE (Bacillusalcalophilus) |
no annotation | 5 | LEU A 211GLY A 63TYR A 62ILE A 302THR A 292 | None | 1.06A | 1p91B-5yo8A:undetectable | 1p91B-5yo8A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zh5 | LYSINE--TRNA LIGASE (Plasmodiumfalciparum) |
no annotation | 5 | LEU A 133GLY A 156GLY A 137ILE A 110LEU A 122 | None | 1.05A | 1p91B-5zh5A:undetectable | 1p91B-5zh5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d3u | ULVAN LYASE (Nonlabensulvanivorans) |
no annotation | 5 | TYR A 281GLY A 285GLY A 146ILE A 101THR A 113 | 83Y A 404 ( 4.0A)NoneNoneNoneNone | 1.02A | 1p91B-6d3uA:undetectable | 1p91B-6d3uA:undetectable |