SIMILAR PATTERNS OF AMINO ACIDS FOR 1OSV_B_CHCB201_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhq | PROTEIN KINASE SPK1 (Saccharomycescerevisiae) |
PF00498(FHA) | 5 | LEU A 618PHE A 601ILE A 678PHE A 692ILE A 613 | None | 1.39A | 1osvB-1fhqA:undetectable | 1osvB-1fhqA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7k | CATALASE (Proteusmirabilis) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | LEU A 258MET A 124ILE A 322PHE A 201ILE A 260 | None | 1.48A | 1osvB-1h7kA:0.0 | 1osvB-1h7kA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ri3 | MRNA CAPPING ENZYME (Encephalitozooncuniculi) |
PF03291(Pox_MCEL) | 5 | LEU A 71PHE A 147ILE A 155ILE A 160MET A 233 | None | 1.38A | 1osvB-1ri3A:0.0 | 1osvB-1ri3A:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s1e | KV CHANNELINTERACTING PROTEIN1 (Homo sapiens) |
PF13499(EF-hand_7)PF13833(EF-hand_8) | 5 | LEU A 192MET A 182PHE A 178TYR A 134MET A 147 | None | 1.45A | 1osvB-1s1eA:undetectable | 1osvB-1s1eA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2grm | PRGX (Enterococcusfaecalis) |
PF01381(HTH_3) | 5 | LEU A 163ILE A 155PHE A 110ILE A 134TYR A 113 | None | 1.43A | 1osvB-2grmA:undetectable | 1osvB-2grmA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ipc | PREPROTEINTRANSLOCASE SECASUBUNIT (Thermusthermophilus) |
PF01043(SecA_PP_bind)PF07516(SecA_SW)PF07517(SecA_DEAD) | 5 | PHE A 375ILE A 96PHE A 395ILE A 216TYR A 399 | None | 1.23A | 1osvB-2ipcA:0.1 | 1osvB-2ipcA:13.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lf8 | TRANSCRIPTION FACTORETV6 (Mus musculus) |
PF00178(Ets) | 5 | LEU A 394MET A 390ILE A 354PHE A 364ILE A 403 | None | 1.46A | 1osvB-2lf8A:0.0 | 1osvB-2lf8A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vn2 | CHROMOSOMEREPLICATIONINITIATION PROTEIN (Geobacilluskaustophilus) |
no annotation | 5 | LEU A 76MET A 41PHE A 45PHE A 51ILE A 83 | None | 1.40A | 1osvB-2vn2A:undetectable | 1osvB-2vn2A:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzs | PUTATIVEALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 5 | LEU A 311SER A 649MET A 30TYR A 639TRP A 282 | None | 1.47A | 1osvB-2wzsA:0.0 | 1osvB-2wzsA:14.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xa7 | AP-2 COMPLEX SUBUNITBETA (Homo sapiens) |
PF01602(Adaptin_N) | 5 | LEU B 396ILE B 417PHE B 418ILE B 428MET B 448 | None | 1.37A | 1osvB-2xa7B:0.0 | 1osvB-2xa7B:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zsk | 226AA LONGHYPOTHETICALASPARTATE RACEMASE (Pyrococcushorikoshii) |
PF01177(Asp_Glu_race) | 5 | LEU A 38PHE A 34SER A 26ILE A 25ILE A 4 | None | 1.47A | 1osvB-2zskA:0.0 | 1osvB-2zskA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dqp | OXIDOREDUCTASE YLBE (Lactococcuslactis) |
PF13460(NAD_binding_10) | 5 | LEU A 16ILE A 148ILE A 68TYR A 25MET A 186 | None | 1.46A | 1osvB-3dqpA:undetectable | 1osvB-3dqpA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3edi | TOLLOID-LIKE PROTEIN1 (Homo sapiens) |
PF01400(Astacin) | 5 | LEU A 94MET A 34MET A 29ILE A 19ILE A 77 | NoneDMS A 215 ( 3.9A)NoneNoneNone | 1.29A | 1osvB-3ediA:undetectable | 1osvB-3ediA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i1e | LIN2157 PROTEIN (Listeriainnocua) |
PF13180(PDZ_2) | 5 | LEU A 19ILE A 28PHE A 39ILE A 82TYR A 5 | None | 1.39A | 1osvB-3i1eA:undetectable | 1osvB-3i1eA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kg4 | UNCHARACTERIZEDPROTEIN ([Mannheimia]succiniciproducens) |
PF09704(Cas_Cas5d) | 5 | LEU A 186PHE A 16SER A 27PHE A 64TYR A 114 | None | 1.38A | 1osvB-3kg4A:undetectable | 1osvB-3kg4A:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kg4 | UNCHARACTERIZEDPROTEIN ([Mannheimia]succiniciproducens) |
PF09704(Cas_Cas5d) | 5 | PHE A 16SER A 27PHE A 64ILE A 62TYR A 114 | None | 1.30A | 1osvB-3kg4A:undetectable | 1osvB-3kg4A:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r5g | CYAB (Pseudomonasaeruginosa) |
PF00211(Guanylate_cyc) | 5 | MET A 330ILE A 304ILE A 264TYR A 257MET A 310 | None | 1.16A | 1osvB-3r5gA:undetectable | 1osvB-3r5gA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sg1 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE 1 (Bacillusanthracis) |
PF00275(EPSP_synthase) | 5 | MET A 271SER A 263ILE A 264ILE A 295MET A 298 | None | 1.45A | 1osvB-3sg1A:undetectable | 1osvB-3sg1A:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6q | CD180 ANTIGEN (Mus musculus) |
PF13855(LRR_8) | 5 | LEU A 196MET A 193SER A 163ILE A 185PHE A 180 | GOL A 3 (-3.6A)NoneNoneNoneNone | 1.49A | 1osvB-3t6qA:undetectable | 1osvB-3t6qA:17.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tjz | COATOMER SUBUNITGAMMA (Bos taurus) |
PF01602(Adaptin_N) | 5 | LEU B 109MET B 73ILE B 104ILE B 131MET B 95 | None | 1.40A | 1osvB-3tjzB:undetectable | 1osvB-3tjzB:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u4j | NAD-DEPENDENTALDEHYDEDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 5 | LEU A 318SER A 326ILE A 325ILE A 290TYR A 295 | None | 1.16A | 1osvB-3u4jA:undetectable | 1osvB-3u4jA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vzi | CRISPR-ASSOCIATEDPROTEIN CAS5, DVULGSUBTYPE (Xanthomonasoryzae) |
PF09704(Cas_Cas5d) | 5 | PHE A 16SER A 27PHE A 64ILE A 62TYR A 114 | None | 1.31A | 1osvB-3vziA:undetectable | 1osvB-3vziA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxo | CATALASE-PEROXIDASE (Synechococcuselongatus) |
PF00141(peroxidase) | 5 | LEU A 151MET A 89ILE A 158ILE A 138TRP A 148 | None | 1.47A | 1osvB-3wxoA:undetectable | 1osvB-3wxoA:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b3i | FATTY ACIDBETA-OXIDATIONCOMPLEX ALPHA-CHAINFADB (Mycobacteriumtuberculosis) |
PF00378(ECH_1)PF00725(3HCDH)PF02737(3HCDH_N) | 5 | LEU A 559PHE A 509SER A 512ILE A 515ILE A 563 | None | 1.07A | 1osvB-4b3iA:undetectable | 1osvB-4b3iA:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bfr | PHOSPHATIDYLINOSITOL4,5-BISPHOSPHATE3-KINASE CATALYTIC SSUBUNIT BETA ISOFORM (Mus musculus) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka)PF00792(PI3K_C2)PF00794(PI3K_rbd) | 5 | LEU A 927PHE A 952SER A 906ILE A 911ILE A 919 | None | 1.36A | 1osvB-4bfrA:undetectable | 1osvB-4bfrA:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4crm | EUKARYOTIC PEPTIDECHAIN RELEASE FACTORSUBUNIT 1 (Saccharomycescerevisiae) |
PF03464(eRF1_2)PF03465(eRF1_3) | 5 | LEU X 284MET X 407PHE X 298ILE X 404TYR X 300 | None | 1.47A | 1osvB-4crmX:undetectable | 1osvB-4crmX:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cua | BETA-GALACTOSIDASE (Streptococcuspneumoniae) |
no annotation | 5 | LEU A1541SER A1471ILE A1470PHE A1527ILE A1620 | NoneNoneEDO A2650 ( 4.8A)NoneNone | 1.40A | 1osvB-4cuaA:undetectable | 1osvB-4cuaA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e2a | PUTATIVEACETYLTRANSFERASE (Streptococcusmutans) |
PF13673(Acetyltransf_10) | 5 | LEU A 51PHE A 25ILE A 20PHE A 74TYR A 98 | None | 1.42A | 1osvB-4e2aA:undetectable | 1osvB-4e2aA:23.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fch | OUTER MEMBRANEPROTEIN SUSE (Bacteroidesthetaiotaomicron) |
PF16411(SusF_SusE) | 5 | MET A 181PHE A 208ILE A 183PHE A 263ILE A 278 | None | 1.28A | 1osvB-4fchA:undetectable | 1osvB-4fchA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fym | OROTATEPHOSPHORIBOSYLTRANSFERASE (Plasmodiumfalciparum) |
PF00156(Pribosyltran) | 5 | LEU A 116MET A 140PHE A 19ILE A 270MET A 67 | None | 1.03A | 1osvB-4fymA:undetectable | 1osvB-4fymA:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gsn | GLUTATHIONES-TRANSFERASE E2 (Anophelesgambiae) |
PF00043(GST_C)PF13417(GST_N_3) | 5 | LEU A 175MET A 170PHE A 102ILE A 163ILE A 183 | None | 1.16A | 1osvB-4gsnA:undetectable | 1osvB-4gsnA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jr7 | CASEIN KINASE IISUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00069(Pkinase) | 5 | PHE A 220ILE A 85TYR A 185MET A 189TYR A 23 | None | 1.40A | 1osvB-4jr7A:undetectable | 1osvB-4jr7A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nky | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE (Homo sapiens) |
PF00067(p450) | 5 | LEU A 195SER A 180ILE A 179PHE A 300ILE A 198 | None | 1.29A | 1osvB-4nkyA:1.4 | 1osvB-4nkyA:19.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4oiv | BILE ACID RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 291ILE A 339ILE A 356MET A 369TYR A 373 | XX9 A 501 (-4.1A)NoneXX9 A 501 ( 4.6A)XX9 A 501 (-4.5A)None | 1.03A | 1osvB-4oivA:24.8 | 1osvB-4oivA:93.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4oiv | BILE ACID RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 291MET A 294ILE A 356MET A 369TYR A 373 | XX9 A 501 (-4.1A)XX9 A 501 ( 4.3A)XX9 A 501 ( 4.6A)XX9 A 501 (-4.5A)None | 0.83A | 1osvB-4oivA:24.8 | 1osvB-4oivA:93.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4oiv | BILE ACID RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 291MET A 294PHE A 333ILE A 356MET A 369 | XX9 A 501 (-4.1A)XX9 A 501 ( 4.3A)XX9 A 501 (-4.7A)XX9 A 501 ( 4.6A)XX9 A 501 (-4.5A) | 0.81A | 1osvB-4oivA:24.8 | 1osvB-4oivA:93.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4oiv | BILE ACID RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 291MET A 294PHE A 333SER A 336ILE A 356 | XX9 A 501 (-4.1A)XX9 A 501 ( 4.3A)XX9 A 501 (-4.7A)XX9 A 501 (-4.2A)XX9 A 501 ( 4.6A) | 0.66A | 1osvB-4oivA:24.8 | 1osvB-4oivA:93.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4oiv | BILE ACID RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 291MET A 294SER A 336ILE A 356TYR A 373 | XX9 A 501 (-4.1A)XX9 A 501 ( 4.3A)XX9 A 501 (-4.2A)XX9 A 501 ( 4.6A)None | 0.94A | 1osvB-4oivA:24.8 | 1osvB-4oivA:93.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4oiv | BILE ACID RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 291PHE A 333ILE A 339ILE A 356MET A 369 | XX9 A 501 (-4.1A)XX9 A 501 (-4.7A)NoneXX9 A 501 ( 4.6A)XX9 A 501 (-4.5A) | 0.80A | 1osvB-4oivA:24.8 | 1osvB-4oivA:93.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4oiv | BILE ACID RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 291PHE A 333SER A 336ILE A 339ILE A 356 | XX9 A 501 (-4.1A)XX9 A 501 (-4.7A)XX9 A 501 (-4.2A)NoneXX9 A 501 ( 4.6A) | 0.79A | 1osvB-4oivA:24.8 | 1osvB-4oivA:93.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4oiv | BILE ACID RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 291SER A 336ILE A 339ILE A 356TYR A 373 | XX9 A 501 (-4.1A)XX9 A 501 (-4.2A)NoneXX9 A 501 ( 4.6A)None | 0.93A | 1osvB-4oivA:24.8 | 1osvB-4oivA:93.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6r | SPHINGOSINE-1-PHOSPHATE LYASE 1 (Homo sapiens) |
PF00282(Pyridoxal_deC) | 5 | LEU A 453MET A 467SER A 507ILE A 511ILE A 440 | NoneNoneNoneGOL A 902 ( 4.7A)None | 1.44A | 1osvB-4q6rA:undetectable | 1osvB-4q6rA:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qvu | UNCHARACTERIZEDPROTEIN (Bacillus cereus) |
PF16285(DUF4931) | 5 | LEU A 205SER A 88ILE A 89ILE A 185TYR A 76 | None | 1.15A | 1osvB-4qvuA:undetectable | 1osvB-4qvuA:24.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6i | ANTHRAX TOXINEXPRESSIONTRANS-ACTINGPOSITIVE REGULATOR (Bacillusanthracis) |
PF00874(PRD)PF05043(Mga)PF08279(HTH_11) | 5 | PHE A 338SER A 374ILE A 373ILE A 319TYR A 371 | None | 1.32A | 1osvB-4r6iA:undetectable | 1osvB-4r6iA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rku | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1 (Pisum sativum) |
PF00223(PsaA_PsaB) | 5 | LEU A 346PHE A 417ILE A 349TYR A 428TYR A 422 | CLA A1122 ( 4.7A)BCR A6007 ( 4.3A)NoneNoneNone | 1.46A | 1osvB-4rkuA:undetectable | 1osvB-4rkuA:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y23 | GAMMA GLUTAMYLTRANSPEPTIDASE,GAMMA-GLUTAMYLTRANSPEPTIDASE (Bacilluslicheniformis) |
PF01019(G_glu_transpept) | 5 | LEU A 435ILE A 87PHE A 236ILE A 245TYR A 237 | None | 1.04A | 1osvB-4y23A:undetectable | 1osvB-4y23A:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5amq | RNA POLYMERASE L (Californiaencephalitisorthobunyavirus) |
PF04196(Bunya_RdRp)PF15518(L_protein_N) | 5 | LEU A1083MET A 937PHE A1094ILE A 930ILE A 977 | None | 1.40A | 1osvB-5amqA:2.9 | 1osvB-5amqA:7.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c4t | NUCLEAR RECEPTORROR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 454SER A 413ILE A 417PHE A 412ILE A 462 | None | 1.36A | 1osvB-5c4tA:19.8 | 1osvB-5c4tA:29.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dlq | EXPORTIN-4 (Mus musculus) |
no annotation | 5 | LEU B 164ILE B 137PHE B 138ILE B 198TRP B 236 | None | 1.31A | 1osvB-5dlqB:2.0 | 1osvB-5dlqB:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f0o | COHESIN SUBUNITPDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P (Lachanceathermotolerans) |
no annotation | 5 | LEU A 737SER A 707ILE A 706PHE A 714TYR A 783 | None | 1.29A | 1osvB-5f0oA:undetectable | 1osvB-5f0oA:13.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j3p | TYROSYL-DNAPHOSPHODIESTERASE 2 (Homo sapiens) |
PF03372(Exo_endo_phos) | 5 | LEU A 337ILE A 117MET A 183TYR A 168TRP A 119 | None | 1.48A | 1osvB-5j3pA:undetectable | 1osvB-5j3pA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k9t | PROTEIN TRANSLOCASESUBUNIT SECA (Escherichiacoli) |
PF01043(SecA_PP_bind)PF07517(SecA_DEAD) | 5 | PHE A 381ILE A 99PHE A 401ILE A 216TYR A 405 | None | 1.38A | 1osvB-5k9tA:undetectable | 1osvB-5k9tA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o8x | SOLUBLE LYTICTRANSGLYCOSYLASE B (Pseudomonasaeruginosa) |
no annotation | 5 | SER A 101ILE A 304ILE A 66TYR A 61TRP A 58 | None | 1.35A | 1osvB-5o8xA:undetectable | 1osvB-5o8xA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oge | GDP-MANNOSETRANSPORTER 1 (Saccharomycescerevisiae) |
no annotation | 5 | LEU A 200MET A 98ILE A 193ILE A 125TYR A 281 | None | 1.50A | 1osvB-5ogeA:undetectable | 1osvB-5ogeA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uto | EDD DOMAIN PROTEIN,DEGV FAMILY (Staphylococcusaureus) |
no annotation | 5 | LEU A 149MET A 152ILE A 124ILE A 88TYR A 98 | NoneNonePLM A 301 ( 4.9A)NoneNone | 1.13A | 1osvB-5utoA:undetectable | 1osvB-5utoA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ape | BIFUNCTIONAL PROTEINFOLD (Helicobacterpylori) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 5 | LEU A 275MET A 66ILE A 58ILE A 271TYR A 16 | None | 1.45A | 1osvB-6apeA:undetectable | 1osvB-6apeA:22.33 |