SIMILAR PATTERNS OF AMINO ACIDS FOR 1OS6_A_DXCA75

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)

(Escherichia
coli) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain) 		4 ILE B1705
LEU B1709
PHE B1870
GLY B1735
 None
 0.98A 1os6A-1a9xB:
undetectable		 1os6A-1a9xB:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fp9 4-ALPHA-GLUCANOTRANS
FERASE

(Thermus
thermophilus) 		PF02446
(Glyco_hydro_77) 		4 ILE A 304
LEU A 262
PHE A 217
GLY A 297
 None
 0.79A 1os6A-1fp9A:
undetectable		 1os6A-1fp9A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5s URONATE ISOMERASE

(Thermotoga
maritima) 		PF02614
(UxaC) 		4 LEU A 289
PHE A 327
LYS A 278
GLY A 277
 None
 0.80A 1os6A-1j5sA:
undetectable		 1os6A-1j5sA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhd SULFATE
ADENYLYLTRANSFERASE

(Sulfur-oxidizing
endosymbiont of
Riftia
pachyptila) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		4 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.06A 1os6A-1jhdA:
undetectable		 1os6A-1jhdA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jjf ENDO-1,4-BETA-XYLANA
SE Z

(Ruminiclostridium
thermocellum) 		PF00756
(Esterase) 		4 ILE A 248
LEU A 222
PHE A 179
GLY A 236
 None
 0.90A 1os6A-1jjfA:
undetectable		 1os6A-1jjfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfi PHOSPHOGLUCOMUTASE 1

(Paramecium
tetraurelia) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 ILE A 178
LEU A 180
MET A  98
GLY A  64
 None
 0.78A 1os6A-1kfiA:
undetectable		 1os6A-1kfiA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfw CHITINASE B

(Arthrobacter
sp. TAD20) 		PF00704
(Glyco_hydro_18) 		4 ILE A  51
LEU A  39
PHE A  34
GLY A 416
 None
 0.87A 1os6A-1kfwA:
undetectable		 1os6A-1kfwA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kon PROTEIN YEBC

(Escherichia
coli) 		PF01709
(Transcrip_reg) 		4 ILE A 220
LEU A 223
PHE A 117
GLY A  89
 None
 1.08A 1os6A-1konA:
undetectable		 1os6A-1konA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ne3 30S RIBOSOMAL
PROTEIN S28E

(Methanothermococcus
thermolithotrophicus) 		PF01200
(Ribosomal_S28e) 		4 ILE A  52
LEU A  53
MET A  44
GLY A  45
 None
 0.97A 1os6A-1ne3A:
undetectable		 1os6A-1ne3A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pw4 GLYCEROL-3-PHOSPHATE
TRANSPORTER

(Escherichia
coli) 		PF07690
(MFS_1) 		4 ILE A 357
LEU A 268
MET A 418
GLY A 416
 None
 0.98A 1os6A-1pw4A:
undetectable		 1os6A-1pw4A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgo ANAEROBIC COBALAMIN
BIOSYNTHETIC COBALT
CHELATASE

(Salmonella
enterica) 		PF06180
(CbiK) 		4 ILE A 244
LEU A 127
MET A 143
GLY A 144
 None
 1.01A 1os6A-1qgoA:
undetectable		 1os6A-1qgoA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA

(Paracoccus
denitrificans) 		PF00115
(COX1) 		4 ILE A  33
LEU A  36
PHE A 111
GLY A 427
 None
 1.07A 1os6A-1qleA:
undetectable		 1os6A-1qleA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rk2 RIBOKINASE

(Escherichia
coli) 		PF00294
(PfkB) 		4 ILE A 301
LEU A 305
PHE A 243
GLY A 242
 None
 1.07A 1os6A-1rk2A:
undetectable		 1os6A-1rk2A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sql DIHYDRONEOPTERIN
ALDOLASE

(Arabidopsis
thaliana) 		PF02152
(FolB) 		4 ILE A  79
LEU A  97
MET A  27
GLY A  13
 None
 0.90A 1os6A-1sqlA:
undetectable		 1os6A-1sqlA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 ILE A 760
LEU A 764
LYS A 808
PHE A 711
 None
 1.02A 1os6A-1wz2A:
undetectable		 1os6A-1wz2A:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yi7 BETA-XYLOSIDASE,
FAMILY 43 GLYCOSYL
HYDROLASE

(Clostridium
acetobutylicum) 		PF04616
(Glyco_hydro_43) 		4 ILE A 516
LEU A 372
PHE A 380
GLY A 512
 None
 0.98A 1os6A-1yi7A:
undetectable		 1os6A-1yi7A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyc TYROSYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00579
(tRNA-synt_1b) 		4 ILE A 263
LEU A  52
LYS A 114
GLY A 110
 None
 0.94A 1os6A-2cycA:
undetectable		 1os6A-2cycA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dmg KIAA1228 PROTEIN

(Homo sapiens) 		PF00168
(C2) 		4 ILE A  37
LEU A 111
LYS A  68
GLY A 101
 None
 1.00A 1os6A-2dmgA:
undetectable		 1os6A-2dmgA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgc ACETOLACTATE
SYNTHASE, SMALL
SUBUNIT

(Thermotoga
maritima) 		PF01842
(ACT)
PF10369
(ALS_ss_C) 		4 ILE A 174
LYS A 158
PHE A 162
GLY A 138
 None
 0.74A 1os6A-2fgcA:
undetectable		 1os6A-2fgcA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE

(Clostridium
acetobutylicum) 		PF08942
(DUF1919) 		4 ILE A  31
LEU A  20
PHE A  66
GLY A  91
 None
 0.84A 1os6A-2g6tA:
undetectable		 1os6A-2g6tA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hig 6-PHOSPHO-1-FRUCTOKI
NASE

(Trypanosoma
brucei) 		PF00365
(PFK) 		4 ILE A 208
LEU A 185
PHE A 135
GLY A 134
 None
 1.04A 1os6A-2higA:
undetectable		 1os6A-2higA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hr7 INSULIN RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain) 		4 ILE A  13
LEU A  17
PHE A  46
GLY A  68
 None
None
GOL  A 610 (-4.9A)
None
 1.05A 1os6A-2hr7A:
undetectable		 1os6A-2hr7A:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6j SULFOLOBUS
SOLFATARICUS PROTEIN
TYROSINE PHOSPHATASE

(Sulfolobus
solfataricus) 		PF00102
(Y_phosphatase) 		4 ILE A  81
LEU A  85
LYS A   1
GLY A  10
 None
 1.08A 1os6A-2i6jA:
undetectable		 1os6A-2i6jA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0a BETA-1,3-N-ACETYLGLU
COSAMINYLTRANSFERASE
MANIC FRINGE

(Mus musculus) 		PF02434
(Fringe) 		4 ILE A  56
LEU A 156
LYS A 169
GLY A 168
 None
 1.04A 1os6A-2j0aA:
undetectable		 1os6A-2j0aA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ols PHOSPHOENOLPYRUVATE
SYNTHASE

(Neisseria
meningitidis) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 ILE A 739
LEU A 735
PHE A 762
GLY A 755
 None
 0.95A 1os6A-2olsA:
undetectable		 1os6A-2olsA:
6.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN

(Archaeoglobus
fulgidus) 		PF00005
(ABC_tran) 		4 ILE A  72
LEU A  57
MET A   1
GLY A  23
 None
 1.00A 1os6A-2onkA:
undetectable		 1os6A-2onkA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q27 OXALYL-COA
DECARBOXYLASE

(Escherichia
coli) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 ILE A  14
LEU A 147
MET A  99
GLY A  72
 None
 0.97A 1os6A-2q27A:
undetectable		 1os6A-2q27A:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qs8 XAA-PRO DIPEPTIDASE

(Alteromonas
macleodii) 		PF01979
(Amidohydro_1) 		4 LEU A  65
MET A 360
LYS A  20
GLY A  19
 None
 0.98A 1os6A-2qs8A:
undetectable		 1os6A-2qs8A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr2 DIHYDROPYRIMIDINASE

(Homo sapiens) 		PF01979
(Amidohydro_1) 		4 ILE A 405
LEU A  52
LYS A 392
GLY A 444
 None
 1.04A 1os6A-2vr2A:
undetectable		 1os6A-2vr2A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2woz KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 10

(Rattus
norvegicus) 		PF01344
(Kelch_1) 		4 ILE A 443
PHE A 488
LYS A 455
GLY A 454
 None
 1.04A 1os6A-2wozA:
undetectable		 1os6A-2wozA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x1w VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2

(Homo sapiens) 		PF00047
(ig) 		4 ILE L 192
LEU L 161
LYS L 183
GLY L 184
 None
 1.06A 1os6A-2x1wL:
undetectable		 1os6A-2x1wL:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xa2 TREHALOSE-SYNTHASE
TRET

(Pyrococcus
horikoshii) 		PF00534
(Glycos_transf_1) 		4 ILE A 289
LEU A 267
MET A 322
GLY A 245
 None
 1.03A 1os6A-2xa2A:
undetectable		 1os6A-2xa2A:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		5 ILE A 116
LEU A 114
LYS A 125
PHE A 126
GLY A  63
 None
 1.12A 1os6A-2xn6A:
undetectable		 1os6A-2xn6A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afe HYDROXYLASE,
PUTATIVE

(Mycobacterium
tuberculosis) 		PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		4 ILE A  16
LEU A  20
MET A 248
GLY A 247
 None
 0.94A 1os6A-3afeA:
undetectable		 1os6A-3afeA:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b0h NITRITE REDUCTASE

(Nicotiana
tabacum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.95A 1os6A-3b0hA:
undetectable		 1os6A-3b0hA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bji PROTO-ONCOGENE VAV

(Homo sapiens) 		PF00130
(C1_1)
PF00169
(PH)
PF00621
(RhoGEF) 		4 ILE A 433
LEU A 431
MET A 496
LYS A 492
 None
 0.99A 1os6A-3bjiA:
undetectable		 1os6A-3bjiA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3coi MITOGEN-ACTIVATED
PROTEIN KINASE 13

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 166
LEU A 156
MET A 213
GLY A 210
 None
 0.74A 1os6A-3coiA:
undetectable		 1os6A-3coiA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez1 AMINOTRANSFERASE
MOCR FAMILY

(Deinococcus
geothermalis) 		PF12897
(Aminotran_MocR) 		4 ILE A 253
LEU A 306
PHE A 295
GLY A  44
 None
 0.93A 1os6A-3ez1A:
undetectable		 1os6A-3ez1A:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5a FMN
ADENYLYLTRANSFERASE

([Candida]
glabrata) 		PF01507
(PAPS_reduct) 		4 ILE A 277
LYS A  65
PHE A 114
GLY A 224
 None
APC  A 305 (-2.9A)
None
None
 1.02A 1os6A-3g5aA:
undetectable		 1os6A-3g5aA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g85 TRANSCRIPTIONAL
REGULATOR (LACI
FAMILY)

(Clostridium
acetobutylicum) 		PF13377
(Peripla_BP_3) 		4 ILE A 219
LEU A 188
PHE A 247
GLY A 169
 None
 0.83A 1os6A-3g85A:
undetectable		 1os6A-3g85A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iic CHEC DOMAIN PROTEIN

(Shewanella
loihica) 		PF13690
(CheX) 		4 ILE A 150
LEU A  10
PHE A 139
GLY A  28
 None
 1.07A 1os6A-3iicA:
undetectable		 1os6A-3iicA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ixc HEXAPEPTIDE
TRANSFERASE FAMILY
PROTEIN

(Anaplasma
phagocytophilum) 		PF00132
(Hexapep) 		4 ILE A  77
LEU A  89
MET A 102
GLY A 101
 None
 0.95A 1os6A-3ixcA:
undetectable		 1os6A-3ixcA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j7y BL19

(Homo sapiens) 		PF01245
(Ribosomal_L19) 		4 ILE Q 136
LEU Q 190
LYS Q 241
GLY Q 242
 None
 1.02A 1os6A-3j7yQ:
undetectable		 1os6A-3j7yQ:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3js6 UNCHARACTERIZED PARM
PROTEIN

(Staphylococcus
aureus) 		no annotation 4 ILE A 100
PHE A 133
MET A 120
GLY A 119
 None
 1.05A 1os6A-3js6A:
undetectable		 1os6A-3js6A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ky9 PROTO-ONCOGENE VAV

(Homo sapiens) 		PF00130
(C1_1)
PF00169
(PH)
PF00621
(RhoGEF)
PF11971
(CAMSAP_CH) 		4 ILE A 433
LEU A 431
MET A 496
LYS A 492
 None
 1.01A 1os6A-3ky9A:
undetectable		 1os6A-3ky9A:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pua PHD FINGER PROTEIN 2

(Homo sapiens) 		PF02373
(JmjC) 		4 ILE A 239
LEU A 330
LYS A 235
PHE A 332
 None
 0.89A 1os6A-3puaA:
undetectable		 1os6A-3puaA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qb8 A654L PROTEIN

(Paramecium
bursaria
Chlorella virus
1) 		PF00583
(Acetyltransf_1) 		4 ILE A 133
LEU A 129
PHE A 157
GLY A 146
 None
 1.02A 1os6A-3qb8A:
undetectable		 1os6A-3qb8A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqr PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE

(Coxiella
burnetii) 		PF00551
(Formyl_trans_N) 		4 ILE A  79
LEU A  75
PHE A  92
MET A  93
 None
 1.08A 1os6A-3tqrA:
undetectable		 1os6A-3tqrA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4v TELOMERASE-ASSOCIATE
D PROTEIN 82

(Tetrahymena
thermophila) 		PF01336
(tRNA_anti-codon) 		4 LEU A 219
LYS A 211
PHE A 228
GLY A 287
 None
 0.52A 1os6A-3u4vA:
undetectable		 1os6A-3u4vA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ve2 TRANSFERRIN-BINDING
PROTEIN 2

(Neisseria
meningitidis) 		PF01298
(TbpB_B_D)
PF17483
(TbpB_C)
PF17484
(TbpB_A) 		4 ILE A 163
LEU A  47
LYS A 337
GLY A 209
 None
 1.01A 1os6A-3ve2A:
undetectable		 1os6A-3ve2A:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w04 DWARF 88 ESTERASE

(Oryza sativa) 		PF12697
(Abhydrolase_6) 		4 ILE A 132
LEU A 129
PHE A 143
GLY A 145
 None
 1.04A 1os6A-3w04A:
undetectable		 1os6A-3w04A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w1h L-SERYL-TRNA(SEC)
SELENIUM TRANSFERASE

(Aquifex
aeolicus) 		PF03841
(SelA) 		4 ILE A 123
LEU A 127
LYS A 286
GLY A 281
 None
None
LLP  A 285 ( 3.1A)
None
 1.04A 1os6A-3w1hA:
undetectable		 1os6A-3w1hA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w2i NADH-CYTOCHROME B5
REDUCTASE 3

(Sus scrofa) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 ILE A 162
LEU A 193
PHE A 179
GLY A 152
 None
None
None
NAD  A 302 (-3.3A)
 0.90A 1os6A-3w2iA:
undetectable		 1os6A-3w2iA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wzi UNCHARACTERIZED
PROTEIN AF_1864

(Archaeoglobus
fulgidus) 		PF09620
(Cas_csx3) 		4 ILE A  30
LEU A  55
PHE A  16
GLY A  47
 None
None
None
U  C   2 ( 3.6A)
 0.90A 1os6A-3wziA:
undetectable		 1os6A-3wziA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 LEU A 325
PHE A 501
MET A 447
GLY A 373
 None
 1.07A 1os6A-4av6A:
undetectable		 1os6A-4av6A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7g CATALASE

(Corynebacterium
glutamicum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 ILE A 350
LEU A 346
PHE A 215
GLY A 211
 None
 1.02A 1os6A-4b7gA:
undetectable		 1os6A-4b7gA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bf5 ALANINE RACEMASE

(Aeromonas
hydrophila) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 ILE A 176
LEU A 178
LYS A 232
GLY A 231
 None
 1.00A 1os6A-4bf5A:
undetectable		 1os6A-4bf5A:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4df9 PUTATIVE PEPTIDASE

(Bacteroides
fragilis) 		PF09471
(Peptidase_M64)
PF16217
(M64_N) 		4 ILE A 128
LEU A 130
PHE A  95
GLY A  39
 None
 0.96A 1os6A-4df9A:
undetectable		 1os6A-4df9A:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dnx SULFATE
ADENYLYLTRANSFERASE

(Allochromatium
vinosum) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		4 ILE A  99
LEU A 101
PHE A  58
GLY A  57
 None
 1.06A 1os6A-4dnxA:
undetectable		 1os6A-4dnxA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4en2 AP-1 COMPLEX SUBUNIT
MU-1

(Mus musculus) 		no annotation 4 ILE M 253
LEU M 214
LYS M 199
GLY M 196
 None
 0.84A 1os6A-4en2M:
undetectable		 1os6A-4en2M:
13.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hc3 PPCA

(Geobacter
sulfurreducens) 		no annotation 8 ILE A   4
LEU A   6
LYS A  33
LYS A  37
PHE A  41
MET A  45
LYS A  49
GLY A  50
 HEM  A  72 (-4.4A)
HEM  A  74 ( 3.7A)
DXC  A  75 ( 4.4A)
DXC  A  75 ( 2.6A)
DXC  A  75 ( 4.3A)
DXC  A  75 (-4.2A)
DXC  A  75 ( 4.1A)
DXC  A  75 ( 3.7A)
 0.39A 1os6A-4hc3A:
15.7		 1os6A-4hc3A:
98.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hcx ISOCITRATE
DEHYDROGENASE [NADP]

(Mycobacterium
tuberculosis) 		PF00180
(Iso_dh) 		4 ILE A  34
LEU A  38
LYS A 348
GLY A 347
 None
 0.92A 1os6A-4hcxA:
undetectable		 1os6A-4hcxA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hlu ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA

(Thermotoga
maritima) 		no annotation 4 ILE D1058
PHE D1152
LYS D 999
GLY D1001
 None
 1.05A 1os6A-4hluD:
undetectable		 1os6A-4hluD:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hu8 GH10 XYLANASE

(Globitermes
brachycerastes) 		PF00331
(Glyco_hydro_10)
PF02368
(Big_2) 		4 LEU A 148
LYS A 454
MET A 429
GLY A 431
 None
 1.01A 1os6A-4hu8A:
undetectable		 1os6A-4hu8A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwv PECTATE LYASE/AMB
ALLERGEN

(Acidovorax
citrulli) 		PF00544
(Pec_lyase_C) 		5 ILE A 417
LEU A 385
MET A 359
LYS A 337
GLY A 358
 None
 1.23A 1os6A-4hwvA:
undetectable		 1os6A-4hwvA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inl SERINE PROTEASE SPLD

(Staphylococcus
aureus) 		PF13365
(Trypsin_2) 		4 ILE A 160
LEU A 161
PHE A 103
GLY A  17
 None
 1.02A 1os6A-4inlA:
undetectable		 1os6A-4inlA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jyp HYDROLASE,
ALPHA/BETA FOLD
FAMILY PROTEIN

(Arabidopsis
thaliana) 		PF12697
(Abhydrolase_6) 		4 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 1.05A 1os6A-4jypA:
undetectable		 1os6A-4jypA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4laf NAD(P)H
DEHYDROGENASE
(QUINONE)

(Pseudomonas sp.
WBC-3) 		PF03358
(FMN_red) 		4 ILE A 145
LEU A 138
PHE A 134
GLY A  81
 None
 1.05A 1os6A-4lafA:
undetectable		 1os6A-4lafA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lr4 HYPOTHETICAL PROTEIN

([Eubacterium]
rectale) 		no annotation 4 ILE A 164
LEU A 219
PHE A 197
GLY A 192
 None
 1.07A 1os6A-4lr4A:
undetectable		 1os6A-4lr4A:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mup AMIDOHYDROLASE

(Agrobacterium
fabrum) 		PF04909
(Amidohydro_2) 		4 ILE A 165
LEU A 200
LYS A 176
GLY A 175
 None
 1.07A 1os6A-4mupA:
undetectable		 1os6A-4mupA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9n CARBOXYLESTERASE

(Sulfolobus
shibatae) 		PF07859
(Abhydrolase_3) 		4 ILE A 174
LEU A  74
PHE A 301
GLY A 144
 None
 1.08A 1os6A-4p9nA:
undetectable		 1os6A-4p9nA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rl3 CHITINASE A

(Pteris
ryukyuensis) 		PF00704
(Glyco_hydro_18) 		4 ILE A 261
LEU A 202
MET A 199
GLY A 241
 None
 1.00A 1os6A-4rl3A:
undetectable		 1os6A-4rl3A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rvh D-MYCAROSE
3-C-METHYLTRANSFERAS
E

(Streptomyces
argillaceus) 		PF08421
(Methyltransf_13)
PF08484
(Methyltransf_14)
PF13489
(Methyltransf_23) 		4 ILE A 322
LEU A 345
LYS A 330
GLY A 331
 None
None
3YN  A 503 (-2.9A)
None
 1.07A 1os6A-4rvhA:
undetectable		 1os6A-4rvhA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8g PUTATIVE
UNCHARACTERIZED
PROTEIN GBS1891

(Streptococcus
agalactiae) 		PF13561
(adh_short_C2) 		4 ILE A 250
LEU A 242
LYS A 171
GLY A 192
 None
 0.80A 1os6A-4u8gA:
undetectable		 1os6A-4u8gA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x6k ANHYDROSIALIDASE

([Ruminococcus]
gnavus) 		PF13088
(BNR_2) 		4 ILE A 642
LEU A 627
LYS A 299
GLY A 686
 None
 0.78A 1os6A-4x6kA:
undetectable		 1os6A-4x6kA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xjn NUCLEOCAPSID

(Mammalian
rubulavirus 5) 		PF00973
(Paramyxo_ncap) 		4 ILE A  99
LEU A  74
LYS A 225
GLY A 226
 None
 1.01A 1os6A-4xjnA:
undetectable		 1os6A-4xjnA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ziu UNCHARACTERIZED
LIPOPROTEIN YFHM

(Escherichia
coli) 		PF07678
(A2M_comp) 		4 ILE A1227
LEU A1231
PHE A1240
GLY A1279
 None
 1.01A 1os6A-4ziuA:
undetectable		 1os6A-4ziuA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aza MALTOSE-BINDING
PERIPLASMIC
PROTEIN,OLIGOSACCHAR
YL TRANSFERASE STT3
SUBUNIT RELATED
PROTEIN

(Escherichia
coli;
Pyrococcus
furiosus) 		PF13416
(SBP_bac_8) 		4 ILE A 132
LEU A 198
LYS A 256
GLY A 191
 None
 0.73A 1os6A-5azaA:
undetectable		 1os6A-5azaA:
6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bpt MGC81278 PROTEIN

(Xenopus laevis) 		PF12894
(ANAPC4_WD40)
PF12896
(ANAPC4) 		5 ILE A 103
LEU A  99
PHE A  97
MET A 185
GLY A 184
 None
 1.42A 1os6A-5bptA:
undetectable		 1os6A-5bptA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cbk SHHTL5

(Striga
hermonthica) 		PF12697
(Abhydrolase_6) 		4 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 0.98A 1os6A-5cbkA:
undetectable		 1os6A-5cbkA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cml OSMC FAMILY PROTEIN

(Rhodothermus
marinus) 		PF12146
(Hydrolase_4) 		4 ILE A 106
LEU A 104
LYS A   1
GLY A  58
 None
 1.02A 1os6A-5cmlA:
undetectable		 1os6A-5cmlA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d27 PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1 PROTEIN

(Homo sapiens) 		PF00169
(PH) 		4 ILE A 361
LEU A 298
LYS A 382
GLY A 276
 None
 0.84A 1os6A-5d27A:
undetectable		 1os6A-5d27A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dnw SHKAI2IB

(Striga
hermonthica) 		PF12697
(Abhydrolase_6) 		4 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 1.02A 1os6A-5dnwA:
undetectable		 1os6A-5dnwA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7r LMO0178 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 ILE E 321
LEU E 317
PHE E 346
GLY E 339
 None
 1.08A 1os6A-5f7rE:
undetectable		 1os6A-5f7rE:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9a ADHESIN BINDING
FUCOSYLATED
HISTO-BLOOD GROUP
ANTIGEN,ADHESIN,ADHE
SIN BINDING
FUCOSYLATED
HISTO-BLOOD GROUP
ANTIGEN

(Helicobacter
pylori) 		no annotation 4 ILE A 450
LEU A 454
PHE A 339
GLY A 332
 None
 0.78A 1os6A-5f9aA:
undetectable		 1os6A-5f9aA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fi0 PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1
PROTEIN,PHOSPHATIDYL
INOSITOL
3,4,5-TRISPHOSPHATE-
DEPENDENT RAC
EXCHANGER 1 PROTEIN

(Homo sapiens) 		PF00169
(PH)
PF00621
(RhoGEF) 		4 ILE A 361
LEU A 298
LYS A 382
GLY A 276
 None
 0.80A 1os6A-5fi0A:
undetectable		 1os6A-5fi0A:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gmx CARBOXYLESTERASE

(uncultured
bacterium) 		PF00144
(Beta-lactamase) 		4 ILE A 294
LEU A 282
PHE A 324
GLY A  75
 None
 0.96A 1os6A-5gmxA:
undetectable		 1os6A-5gmxA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jb3 30S RIBOSOMAL
PROTEIN S9

(Pyrococcus
abyssi) 		PF00380
(Ribosomal_S9) 		4 ILE K  45
LEU K  49
LYS K  23
GLY K  24
 None
None
G  21097 ( 3.7A)
None
 0.84A 1os6A-5jb3K:
undetectable		 1os6A-5jb3K:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jy5 THIOREDOXIN

(Cryptococcus
neoformans) 		PF00085
(Thioredoxin) 		4 ILE A  95
LEU A  99
PHE A  52
GLY A  45
 None
 1.05A 1os6A-5jy5A:
undetectable		 1os6A-5jy5A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k53 ALDEHYDE
DEFORMYLATING
OXYGENASE

(Oscillatoria
sp.) 		PF11266
(Ald_deCOase) 		4 ILE A 176
LEU A 180
PHE A  87
GLY A  31
 None
None
None
STE  A 502 ( 3.9A)
 1.07A 1os6A-5k53A:
undetectable		 1os6A-5k53A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksd ATPASE 2, PLASMA
MEMBRANE-TYPE

(Arabidopsis
thaliana) 		PF00122
(E1-E2_ATPase)
PF00690
(Cation_ATPase_N)
PF00702
(Hydrolase) 		4 ILE A 497
LEU A 625
MET A 585
GLY A 584
 None
 0.79A 1os6A-5ksdA:
undetectable		 1os6A-5ksdA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me3 SISTER CHROMATID
COHESION PROTEIN 2

(Eremothecium
gossypii) 		PF12765
(Cohesin_HEAT)
PF12830
(Nipped-B_C) 		4 ILE A 486
LEU A 490
PHE A 504
GLY A 555
 None
 0.79A 1os6A-5me3A:
undetectable		 1os6A-5me3A:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npy FLAGELLAR BASAL BODY
PROTEIN

(Helicobacter
pylori) 		no annotation 4 ILE A 352
LEU A 310
PHE A 224
GLY A 280
 None
 1.04A 1os6A-5npyA:
undetectable		 1os6A-5npyA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9g CHROMO
DOMAIN-CONTAINING
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 ILE W 691
LEU W 687
LYS W 708
GLY W 735
 None
 0.84A 1os6A-5o9gW:
undetectable		 1os6A-5o9gW:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oo7 SLA2

(Chaetomium
thermophilum) 		no annotation 4 ILE A 171
LEU A 167
PHE A 140
GLY A 138
 None
 0.87A 1os6A-5oo7A:
undetectable		 1os6A-5oo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vc7 VCP-LIKE ATPASE

(Thermoplasma
acidophilum) 		PF00004
(AAA) 		4 ILE A 599
LEU A 596
PHE A 627
GLY A 609
 None
 1.04A 1os6A-5vc7A:
undetectable		 1os6A-5vc7A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w75 ELONGATION FACTOR TU

(Thermotoga
neapolitana) 		no annotation 4 ILE A  32
LEU A 192
MET A 131
GLY A 101
 None
 1.07A 1os6A-5w75A:
undetectable		 1os6A-5w75A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6j NUCLEOPROTEIN

(Tomato spotted
wilt
orthotospovirus) 		PF01533
(Tospo_nucleocap) 		4 ILE A 100
LEU A  96
PHE A  74
GLY A  75
 None
 1.03A 1os6A-5y6jA:
undetectable		 1os6A-5y6jA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 4 ILE A  26
LEU A  39
PHE A  89
GLY A  88
 None
 0.92A 1os6A-5ze4A:
undetectable		 1os6A-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eki CARBONIC ANHYDRASE

(Persephonella
marina) 		no annotation 4 ILE A 162
LEU A 187
PHE A 116
GLY A  84
 None
 0.89A 1os6A-6ekiA:
undetectable		 1os6A-6ekiA:
undetectable