SIMILAR PATTERNS OF AMINO ACIDS FOR 1ONI_I_BEZI517
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a5c | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE (Plasmodiumfalciparum) |
PF00274(Glycolytic) | 4 | ILE A 45GLU A 40PHE A 69ALA A 38 | None | 1.02A | 1oniG-1a5cA:undetectable1oniI-1a5cA:undetectable | 1oniG-1a5cA:16.901oniI-1a5cA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dqp | GUANINEPHOSPHORIBOSYLTRANSFERASE (Giardiaintestinalis) |
PF00156(Pribosyltran) | 4 | ILE A 219GLU A 40PHE A 150ALA A 36 | None | 1.11A | 1oniG-1dqpA:undetectable1oniI-1dqpA:undetectable | 1oniG-1dqpA:18.471oniI-1dqpA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fhe | GLUTATHIONETRANSFERASE (Fasciolahepatica) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | ILE A 70PRO A 55ARG A 17ALA A 13 | None | 1.11A | 1oniG-1fheA:undetectable1oniI-1fheA:undetectable | 1oniG-1fheA:20.671oniI-1fheA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fui | L-FUCOSE ISOMERASE (Escherichiacoli) |
PF02952(Fucose_iso_C)PF07881(Fucose_iso_N1)PF07882(Fucose_iso_N2) | 4 | ILE A 391PRO A 500PHE A 450ALA A 396 | None | 0.91A | 1oniG-1fuiA:undetectable1oniI-1fuiA:undetectable | 1oniG-1fuiA:13.541oniI-1fuiA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8x | MYOSIN II HEAVYCHAIN FUSED TOALPHA-ACTININ 3 (Dictyosteliumdiscoideum) |
PF00063(Myosin_head)PF00435(Spectrin)PF02736(Myosin_N) | 4 | TYR A 135ILE A 115PRO A 128ARG A 131 | NoneNoneADP A1100 ( 4.6A)ADP A1100 ( 4.0A) | 1.11A | 1oniG-1g8xA:undetectable1oniI-1g8xA:undetectable | 1oniG-1g8xA:8.621oniI-1g8xA:8.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1j7h | HYPOTHETICAL PROTEINHI0719 (Haemophilusinfluenzae) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 18ILE A 34PRO A 116GLU A 122 | None | 0.56A | 1oniG-1j7hA:18.81oniI-1j7hA:18.8 | 1oniG-1j7hA:42.961oniI-1j7hA:42.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jd1 | HYPOTHETICAL 13.9KDA PROTEIN INFCY2-PET117INTERGENIC REGION (Saccharomycescerevisiae) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 20ILE A 36PRO A 114GLU A 120 | None | 0.39A | 1oniG-1jd1A:23.11oniI-1jd1A:22.7 | 1oniG-1jd1A:38.641oniI-1jd1A:38.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m22 | PEPTIDE AMIDASE (Stenotrophomonasmaltophilia) |
PF01425(Amidase) | 4 | PRO A 527PHE A 529ARG A 74ALA A 212 | None | 1.03A | 1oniG-1m22A:undetectable1oniI-1m22A:undetectable | 1oniG-1m22A:16.851oniI-1m22A:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odo | PUTATIVE CYTOCHROMEP450 154A1 (Streptomycescoelicolor) |
PF00067(p450) | 4 | ILE A 150PRO A 149ARG A 141ALA A 145 | None | 1.10A | 1oniG-1odoA:undetectable1oniI-1odoA:undetectable | 1oniG-1odoA:19.551oniI-1odoA:19.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1oni | 14.5 KDATRANSLATIONALINHIBITOR PROTEIN (Homo sapiens) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 21ILE A 37PRO A 116GLU A 122 | None | 0.45A | 1oniG-1oniA:26.31oniI-1oniA:27.3 | 1oniG-1oniA:100.001oniI-1oniA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qah | PERCHLORIC ACIDSOLUBLE PROTEIN (Rattusnorvegicus) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 20ILE A 36PRO A 115GLU A 121 | None | 0.21A | 1oniG-1qahA:26.41oniI-1qahA:25.9 | 1oniG-1qahA:87.501oniI-1qahA:87.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qd1 | FORMIMINOTRANSFERASE-CYCLODEAMINASE (Sus scrofa) |
PF02971(FTCD)PF07837(FTCD_N) | 4 | ILE A 322PRO A 274GLU A 323PHE A 241 | None | 1.05A | 1oniG-1qd1A:2.51oniI-1qd1A:undetectable | 1oniG-1qd1A:19.941oniI-1qd1A:19.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qd9 | PURINE REGULATORYPROTEIN YABJ (Bacillussubtilis) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 17ILE A 33PRO A 111GLU A 117 | None | 0.54A | 1oniG-1qd9A:23.21oniI-1qd9A:23.2 | 1oniG-1qd9A:42.221oniI-1qd9A:42.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qu9 | YJGF PROTEIN (Escherichiacoli) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 17ILE A 33PRO A 114GLU A 120 | None | 0.44A | 1oniG-1qu9A:21.81oniI-1qu9A:21.9 | 1oniG-1qu9A:44.781oniI-1qu9A:44.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 1 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | TYR A 305ILE A 340GLU A 355ALA A 308 | NoneNone MG A1095 (-2.8A)None | 1.11A | 1oniG-1tqyA:undetectable1oniI-1tqyA:undetectable | 1oniG-1tqyA:15.491oniI-1tqyA:15.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vjk | MOLYBDOPTERINCONVERTING FACTOR,SUBUNIT 1 (Pyrococcusfuriosus) |
PF02597(ThiS) | 4 | ILE A 23GLU A 21PHE A 45ALA A 16 | None | 1.10A | 1oniG-1vjkA:undetectable1oniI-1vjkA:undetectable | 1oniG-1vjkA:21.091oniI-1vjkA:21.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1x25 | HYPOTHETICAL UPF0076PROTEIN ST0811 (Sulfurisphaeratokodaii) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 16ILE A 32PRO A 111GLU A 117 | None | 0.49A | 1oniG-1x25A:24.01oniI-1x25A:24.0 | 1oniG-1x25A:43.611oniI-1x25A:43.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xpg | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Thermotogamaritima) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | TYR A 232ILE A 148PHE A 106ALA A 202 | NoneNoneMRY A1890 (-3.7A)None | 1.12A | 1oniG-1xpgA:undetectable1oniI-1xpgA:undetectable | 1oniG-1xpgA:11.991oniI-1xpgA:11.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xrg | PUTATIVE TRANSLATIONINITIATIONINHIBITOR, YJGFFAMILY (Ruminiclostridiumthermocellum) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 18ILE A 34PRO A 113GLU A 119 | UNX A 509 (-3.7A)NoneNoneNone | 0.47A | 1oniG-1xrgA:23.81oniI-1xrgA:23.8 | 1oniG-1xrgA:44.521oniI-1xrgA:44.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a1a | INTERFERON-INDUCED,DOUBLE-STRANDEDRNA-ACTIVATEDPROTEIN KINASE (Homo sapiens) |
PF00069(Pkinase) | 4 | TYR B 454ILE B 378PHE B 494ALA B 479 | None | 1.06A | 1oniG-2a1aB:undetectable1oniI-2a1aB:undetectable | 1oniG-2a1aB:18.281oniI-2a1aB:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2abj | BRANCHED-CHAIN-AMINO-ACIDAMINOTRANSFERASE,CYTOSOLIC (Homo sapiens) |
PF01063(Aminotran_4) | 4 | PRO A 357GLU A 325PHE A 197ALA A 360 | None | 1.11A | 1oniG-2abjA:undetectable1oniI-2abjA:undetectable | 1oniG-2abjA:20.861oniI-2abjA:20.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2b33 | PROTEIN SYNTHESISINHIBITOR, PUTATIVE (Thermotogamaritima) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 17ILE A 33PRO A 112GLU A 118 | None | 0.45A | 1oniG-2b33A:23.01oniI-2b33A:23.3 | 1oniG-2b33A:42.141oniI-2b33A:42.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2cwj | PUTATIVEENDONUCLEASE (Aeropyrumpernix) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 11ILE A 27PRO A 106GLU A 112 | None | 0.77A | 1oniG-2cwjA:19.31oniI-2cwjA:19.2 | 1oniG-2cwjA:39.861oniI-2cwjA:39.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2etv | IRON(III) ABCTRANSPORTER,PERIPLASMICIRON-BINDINGPROTEIN, PUTATIVE (Thermotogamaritima) |
PF01497(Peripla_BP_2) | 4 | ILE A 302PRO A 214PHE A 144ALA A 295 | None | 0.93A | 1oniG-2etvA:undetectable1oniI-2etvA:undetectable | 1oniG-2etvA:18.811oniI-2etvA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fja | ADENYLYLSULFATEREDUCTASE, SUBUNIT AADENYLYLSULFATEREDUCTASE, SUBUNIT B (Archaeoglobusfulgidus;Archaeoglobusfulgidus) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C)PF12139(APS-reductase_C)PF13187(Fer4_9) | 4 | ILE B 724PRO B 726PHE A 238ALA A 67 | None | 1.11A | 1oniG-2fjaB:undetectable1oniI-2fjaB:undetectable | 1oniG-2fjaB:19.381oniI-2fjaB:19.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fpg | SUCCINYL-COA LIGASE[GDP-FORMING]ALPHA-CHAIN,MITOCHONDRIALSUCCINYL-COA LIGASE[GDP-FORMING]BETA-CHAIN,MITOCHONDRIAL (Sus scrofa;Sus scrofa) |
PF00549(Ligase_CoA)PF02629(CoA_binding)PF00549(Ligase_CoA)PF08442(ATP-grasp_2) | 4 | ILE A 218GLU A 217PHE B 293ALA B 273 | NoneNoneNonePO4 A 401 (-3.8A) | 1.05A | 1oniG-2fpgA:undetectable1oniI-2fpgA:undetectable | 1oniG-2fpgA:22.351oniI-2fpgA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g17 | N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATEREDUCTASE (Salmonellaenterica) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | ILE A 218PRO A 156GLU A 217ARG A 213 | NoneNoneNoneSO4 A 410 (-3.0A) | 0.96A | 1oniG-2g17A:undetectable1oniI-2g17A:undetectable | 1oniG-2g17A:19.531oniI-2g17A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hcu | 3-ISOPROPYLMALATEDEHYDRATASE SMALLSUBUNIT (Streptococcusmutans) |
PF00694(Aconitase_C) | 4 | TYR A 48PRO A 26GLU A 45PHE A 29 | None | 1.08A | 1oniG-2hcuA:undetectable1oniI-2hcuA:undetectable | 1oniG-2hcuA:20.851oniI-2hcuA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hi1 | 4-HYDROXYTHREONINE-4-PHOSPHATEDEHYDROGENASE 2 (Salmonellaenterica) |
PF04166(PdxA) | 4 | TYR A 267PRO A 248PHE A 252ALA A 208 | None | 1.10A | 1oniG-2hi1A:2.71oniI-2hi1A:undetectable | 1oniG-2hi1A:18.771oniI-2hi1A:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iod | DIHYDROFLAVONOL4-REDUCTASE (Vitis vinifera) |
PF01370(Epimerase) | 4 | ILE A 213PRO A 212PHE A 280ALA A 264 | None | 1.12A | 1oniG-2iodA:undetectable1oniI-2iodA:undetectable | 1oniG-2iodA:16.081oniI-2iodA:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j66 | BTRK (Bacilluscirculans) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | ILE A 139PRO A 141GLU A 163PHE A 145 | None | 1.01A | 1oniG-2j66A:undetectable1oniI-2j66A:undetectable | 1oniG-2j66A:16.461oniI-2j66A:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qag | SEPTIN-2SEPTIN-6 (Homo sapiens;Homo sapiens) |
PF00735(Septin)PF00735(Septin) | 4 | ILE B 183PRO B 157PHE A 156ALA B 188 | None | 0.81A | 1oniG-2qagB:undetectable1oniI-2qagB:undetectable | 1oniG-2qagB:15.281oniI-2qagB:15.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qp2 | UNKNOWN PROTEIN (Photorhabduslaumondii) |
PF01823(MACPF) | 4 | ILE A 70PRO A 90ARG A 28ALA A 41 | None | 0.92A | 1oniG-2qp2A:undetectable1oniI-2qp2A:undetectable | 1oniG-2qp2A:21.991oniI-2qp2A:21.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2uyk | PROTEIN TDCF (Escherichiacoli) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 17ILE A 33PRO A 114GLU A 120 | None | 0.23A | 1oniG-2uykA:22.31oniI-2uykA:22.2 | 1oniG-2uykA:39.011oniI-2uykA:39.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8o | LIPOPOLYSACCHARIDEBIOSYNTHESIS PROTEINWZZE (Escherichiacoli) |
no annotation | 4 | TYR A 102ILE A 61PHE A 154ARG A 64 | None | 0.77A | 1oniG-3b8oA:undetectable1oniI-3b8oA:undetectable | 1oniG-3b8oA:20.461oniI-3b8oA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bc1 | RAS-RELATED PROTEINRAB-27A (Mus musculus) |
PF00071(Ras) | 4 | TYR A 122ILE A 181PHE A 95ALA A 92 | None | 1.06A | 1oniG-3bc1A:undetectable1oniI-3bc1A:undetectable | 1oniG-3bc1A:22.501oniI-3bc1A:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bzm | MENAQUINONE-SPECIFICISOCHORISMATESYNTHASE (Escherichiacoli) |
PF00425(Chorismate_bind) | 4 | TYR A 368ILE A 417PHE A 363ALA A 196 | None | 1.09A | 1oniG-3bzmA:undetectable1oniI-3bzmA:undetectable | 1oniG-3bzmA:15.941oniI-3bzmA:15.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3do6 | FORMATE--TETRAHYDROFOLATE LIGASE (Thermotogamaritima) |
PF01268(FTHFS) | 4 | ILE A 193GLU A 189ARG A 222ALA A 503 | None | 1.10A | 1oniG-3do6A:undetectable1oniI-3do6A:undetectable | 1oniG-3do6A:14.811oniI-3do6A:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fmy | HTH-TYPETRANSCRIPTIONALREGULATOR MQSA(YGIT/B3021) (Escherichiacoli) |
PF15731(MqsA_antitoxin) | 4 | ILE A 74PRO A 109ARG A 101ALA A 107 | NoneMEQ A 108 ( 2.6A)NoneMEQ A 108 ( 3.1A) | 0.87A | 1oniG-3fmyA:undetectable1oniI-3fmyA:undetectable | 1oniG-3fmyA:20.141oniI-3fmyA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gnl | UNCHARACTERIZEDPROTEIN, DUF633,LMOF2365_1472 (Listeriamonocytogenes) |
PF04816(TrmK) | 4 | ILE A 108PRO A 129ARG A 137ALA A 133 | None | 1.12A | 1oniG-3gnlA:undetectable1oniI-3gnlA:undetectable | 1oniG-3gnlA:20.081oniI-3gnlA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gs6 | BETA-HEXOSAMINIDASE (Vibrio cholerae) |
PF00933(Glyco_hydro_3) | 4 | TYR A 223ILE A 184PRO A 163ALA A 218 | None | 0.91A | 1oniG-3gs6A:undetectable1oniI-3gs6A:undetectable | 1oniG-3gs6A:18.241oniI-3gs6A:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iiw | POLYCOMB PROTEIN EED (Homo sapiens) |
PF00400(WD40) | 4 | TYR A 186ILE A 183PHE A 198ALA A 164 | None | 0.98A | 1oniG-3iiwA:undetectable1oniI-3iiwA:undetectable | 1oniG-3iiwA:16.211oniI-3iiwA:16.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3k0t | ENDORIBONUCLEASEL-PSP, PUTATIVE (Pseudomonassyringae groupgenomosp. 3) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 18ILE A 34PRO A 112GLU A 118 | BGC A 127 (-3.1A)BGC A 127 (-4.0A)NoneBGC A 127 (-3.5A) | 0.63A | 1oniG-3k0tA:23.11oniI-3k0tA:23.0 | 1oniG-3k0tA:40.941oniI-3k0tA:40.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kx6 | FRUCTOSE-BISPHOSPHATE ALDOLASE (Babesia bovis) |
PF00274(Glycolytic) | 4 | ILE A 37GLU A 32PHE A 61ALA A 30 | None | 0.92A | 1oniG-3kx6A:undetectable1oniI-3kx6A:undetectable | 1oniG-3kx6A:20.111oniI-3kx6A:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l22 | SUSD SUPERFAMILYPROTEIN (Bacteroidesfragilis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | ILE A 262GLU A 271PHE A 412ALA A 351 | None | 1.05A | 1oniG-3l22A:undetectable1oniI-3l22A:undetectable | 1oniG-3l22A:18.801oniI-3l22A:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ll7 | PUTATIVEMETHYLTRANSFERASE (Porphyromonasgingivalis) |
no annotation | 4 | ILE A 279GLU A 276PHE A 269ALA A 303 | None | 1.10A | 1oniG-3ll7A:undetectable1oniI-3ll7A:undetectable | 1oniG-3ll7A:16.631oniI-3ll7A:16.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mmt | FRUCTOSE-BISPHOSPHATE ALDOLASE (Bartonellahenselae) |
PF00274(Glycolytic) | 4 | ILE A 29GLU A 24PHE A 53ALA A 22 | None2FP A 350 ( 4.9A)NoneNone | 0.98A | 1oniG-3mmtA:undetectable1oniI-3mmtA:undetectable | 1oniG-3mmtA:19.881oniI-3mmtA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mnf | PAC2 FAMILY PROTEIN (Streptomycesavermitilis) |
PF09754(PAC2) | 4 | ILE A 98PRO A 75PHE A 56ALA A 50 | None | 1.09A | 1oniG-3mnfA:undetectable1oniI-3mnfA:undetectable | 1oniG-3mnfA:21.631oniI-3mnfA:21.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mqw | PUTATIVEENDORIBONUCLEASEL-PSP (Entamoebahistolytica) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 19ILE A 35PRO A 114GLU A 120 | FLC A 140 (-4.0A)FLC A 140 (-4.8A)FLC A 140 (-4.5A)FLC A 140 (-2.8A) | 0.46A | 1oniG-3mqwA:22.81oniI-3mqwA:23.0 | 1oniG-3mqwA:42.751oniI-3mqwA:42.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ouh | EGL NINE HOMOLOG 1 (Homo sapiens) |
PF13640(2OG-FeII_Oxy_3) | 4 | TYR A 303ILE A 256ARG A 383ALA A 385 | NoneNone014 A 417 (-3.1A)014 A 417 ( 3.9A) | 1.00A | 1oniG-3ouhA:undetectable1oniI-3ouhA:undetectable | 1oniG-3ouhA:20.001oniI-3ouhA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oui | EGL NINE HOMOLOG 1 (Homo sapiens) |
PF13640(2OG-FeII_Oxy_3) | 4 | TYR A 303ILE A 256ARG A 383ALA A 385 | NoneNone42Z A 393 (-2.9A)42Z A 393 ( 4.3A) | 0.94A | 1oniG-3ouiA:undetectable1oniI-3ouiA:undetectable | 1oniG-3ouiA:21.231oniI-3ouiA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qnk | PUTATIVE LIPOPROTEIN (Bacteroidesfragilis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | ILE A 251GLU A 261PHE A 471ALA A 416 | None | 1.02A | 1oniG-3qnkA:undetectable1oniI-3qnkA:undetectable | 1oniG-3qnkA:14.861oniI-3qnkA:14.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3quw | PROTEIN MMF1 (Saccharomycescerevisiae) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 36ILE A 52PRO A 130GLU A 136 | None | 0.41A | 1oniG-3quwA:22.51oniI-3quwA:22.4 | 1oniG-3quwA:32.681oniI-3quwA:32.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3r0p | L-PSP PUTATIVEENDORIBONUCLEASE (unculturedorganism) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 19ILE A 35PRO A 114GLU A 120 | None | 0.57A | 1oniG-3r0pA:23.31oniI-3r0pA:23.4 | 1oniG-3r0pA:43.181oniI-3r0pA:43.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u9r | METHYLCROTONYL-COACARBOXYLASE,BETA-SUBUNIT (Pseudomonasaeruginosa) |
PF01039(Carboxyl_trans) | 4 | ILE B 553PRO B 435PHE B 437ALA B 548 | None | 0.63A | 1oniG-3u9rB:undetectable1oniI-3u9rB:undetectable | 1oniG-3u9rB:13.651oniI-3u9rB:13.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uat | DISKS LARGE HOMOLOG1 (Rattusnorvegicus) |
PF00625(Guanylate_kin)PF07653(SH3_2) | 4 | ILE A 845PRO A 839PHE A 836ALA A 864 | None | 1.10A | 1oniG-3uatA:undetectable1oniI-3uatA:undetectable | 1oniG-3uatA:20.271oniI-3uatA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3umv | DEOXYRIBODIPYRIMIDINE PHOTO-LYASE (Oryza sativa) |
PF00875(DNA_photolyase) | 4 | ILE A 121PRO A 118PHE A 77ALA A 146 | NoneNoneURE A 904 (-4.6A)None | 0.94A | 1oniG-3umvA:undetectable1oniI-3umvA:undetectable | 1oniG-3umvA:16.891oniI-3umvA:16.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vcz | ENDORIBONUCLEASEL-PSP (Vibriovulnificus) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 17ILE A 33PRO A 115GLU A 121 | None | 0.39A | 1oniG-3vczA:21.41oniI-3vczA:21.5 | 1oniG-3vczA:37.011oniI-3vczA:37.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aah | METHANOLDEHYDROGENASE (Methylophilusmethylotrophus) |
PF13360(PQQ_2) | 4 | ILE A 508PRO A 532PHE A 553ALA A 465 | None | 1.10A | 1oniG-4aahA:undetectable1oniI-4aahA:undetectable | 1oniG-4aahA:13.391oniI-4aahA:13.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aio | LIMIT DEXTRINASE (Hordeum vulgare) |
PF02922(CBM_48)PF11852(DUF3372) | 4 | TYR A 766PRO A 681PHE A 683ALA A 675 | None | 0.83A | 1oniG-4aioA:undetectable1oniI-4aioA:undetectable | 1oniG-4aioA:10.251oniI-4aioA:10.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bn5 | NAD-DEPENDENTPROTEIN DEACETYLASESIRTUIN-3,MITOCHONDRIAL (Homo sapiens) |
PF02146(SIR2) | 4 | ILE A 268PRO A 289PHE A 192ALA A 196 | None | 1.11A | 1oniG-4bn5A:undetectable1oniI-4bn5A:undetectable | 1oniG-4bn5A:19.351oniI-4bn5A:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d2j | FRUCTOSE-BISPHOSPHATE ALDOLASE (Toxoplasmagondii) |
PF00274(Glycolytic) | 4 | ILE A 110GLU A 105PHE A 134ALA A 103 | None | 0.83A | 1oniG-4d2jA:undetectable1oniI-4d2jA:undetectable | 1oniG-4d2jA:17.751oniI-4d2jA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4egw | MAGNESIUM TRANSPORTPROTEIN CORA (Methanocaldococcusjannaschii) |
PF01544(CorA) | 4 | ILE A 143PRO A 81PHE A 83ARG A 149 | None | 1.05A | 1oniG-4egwA:undetectable1oniI-4egwA:undetectable | 1oniG-4egwA:19.861oniI-4egwA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f5x | RNA-DIRECTED RNAPOLYMERASE (Rotavirus A) |
PF02123(RdRP_4)PF12289(Rotavirus_VP1) | 4 | ILE W 471PRO W 435GLU W 390ARG W 814 | None | 0.99A | 1oniG-4f5xW:undetectable1oniI-4f5xW:undetectable | 1oniG-4f5xW:8.951oniI-4f5xW:8.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fn7 | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Mycobacteriumtuberculosis) |
PF00378(ECH_1) | 4 | TYR A 154ILE A 137PHE A 174ALA A 157 | None | 1.11A | 1oniG-4fn7A:undetectable1oniI-4fn7A:undetectable | 1oniG-4fn7A:23.811oniI-4fn7A:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gvf | BETA-HEXOSAMINIDASE (Salmonellaenterica) |
PF00933(Glyco_hydro_3) | 4 | TYR A 229ILE A 189PRO A 166ALA A 224 | None | 1.00A | 1oniG-4gvfA:undetectable1oniI-4gvfA:undetectable | 1oniG-4gvfA:15.341oniI-4gvfA:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hkx | HEMAGGLUTININ HA1 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | TYR E 195ILE E 217PRO E 215ALA E 200 | None | 1.09A | 1oniG-4hkxE:undetectable1oniI-4hkxE:undetectable | 1oniG-4hkxE:20.391oniI-4hkxE:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k0e | HEAVY METAL CATIONTRICOMPONENT EFFLUXPUMP ZNEA(CZCA-LIKE) (Cupriavidusmetallidurans) |
PF00873(ACR_tran) | 4 | TYR A 458ILE A 382PHE A 451ALA A 465 | None | 1.06A | 1oniG-4k0eA:undetectable1oniI-4k0eA:undetectable | 1oniG-4k0eA:9.301oniI-4k0eA:9.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4klz | GTP-BINDING PROTEINRIT1 (Homo sapiens) |
PF00071(Ras) | 4 | PRO A 159GLU A 181PHE A 161ALA A 177 | None | 0.94A | 1oniG-4klzA:undetectable1oniI-4klzA:undetectable | 1oniG-4klzA:23.121oniI-4klzA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lyp | EXO-BETA-1,4-MANNOSIDASE (Rhizomucormiehei) |
no annotation | 4 | TYR A 319PRO A 266GLU A 259ALA A 305 | None | 1.12A | 1oniG-4lypA:undetectable1oniI-4lypA:undetectable | 1oniG-4lypA:16.191oniI-4lypA:16.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4myd | 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATESYNTHASE (Escherichiacoli) |
PF12697(Abhydrolase_6) | 4 | ILE A 107PHE A 37ARG A 251ALA A 247 | None | 1.10A | 1oniG-4mydA:undetectable1oniI-4mydA:undetectable | 1oniG-4mydA:20.921oniI-4mydA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n30 | PROTEIN DISULFIDEISOMERASE (Pseudomonasaeruginosa) |
PF13462(Thioredoxin_4) | 4 | ILE A 172PRO A 94ARG A 107ALA A 106 | None | 1.05A | 1oniG-4n30A:undetectable1oniI-4n30A:undetectable | 1oniG-4n30A:17.891oniI-4n30A:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9u | NAD(P)TRANSHYDROGENASESUBUNIT BETA (Thermusthermophilus) |
PF02233(PNTB) | 4 | ILE B 99GLU B 221PHE B 109ALA B 118 | None | 0.99A | 1oniG-4o9uB:undetectable1oniI-4o9uB:undetectable | 1oniG-4o9uB:16.921oniI-4o9uB:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9x | TCDB2, TCCC3 (Photorhabdusluminescens) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 4 | TYR A2086ILE A1784GLU A1798ALA A2064 | None | 1.06A | 1oniG-4o9xA:undetectable1oniI-4o9xA:undetectable | 1oniG-4o9xA:5.071oniI-4o9xA:5.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qaw | XYN30D (Paenibacillusbarcinonensis) |
PF03422(CBM_6)PF17189(Glyco_hydro_30C) | 4 | TYR A 212ILE A 181PRO A 172ALA A 200 | None | 1.03A | 1oniG-4qawA:2.21oniI-4qawA:undetectable | 1oniG-4qawA:14.771oniI-4qawA:14.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rml | LATROPHILIN-3 (Mus musculus) |
PF02191(OLF) | 4 | TYR A 389PRO A 204GLU A 337PHE A 459 | None | 1.10A | 1oniG-4rmlA:undetectable1oniI-4rmlA:undetectable | 1oniG-4rmlA:18.011oniI-4rmlA:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w66 | GLUTATHIONES-TRANSFERASE DOMAINPROTEIN (Haliangiumochraceum) |
PF14497(GST_C_3) | 4 | ILE A 71PRO A 56ARG A 20ALA A 16 | None | 1.09A | 1oniG-4w66A:undetectable1oniI-4w66A:undetectable | 1oniG-4w66A:21.491oniI-4w66A:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wsp | PROTEIN DL-RV1738 (Mycobacteriumtuberculosis) |
PF08962(DUF1876) | 4 | ILE A 57PRO A 49ARG A 65ALA A 45 | NoneNone CL A 101 ( 3.5A) CL A 101 ( 4.0A) | 1.03A | 1oniG-4wspA:undetectable1oniI-4wspA:undetectable | 1oniG-4wspA:26.091oniI-4wspA:26.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5anb | 60S RIBOSOMALPROTEIN L10 (Dictyosteliumdiscoideum) |
PF00252(Ribosomal_L16) | 4 | ILE F 65PRO F 93ARG F 32ALA F 29 | NoneNone U N1222 ( 3.3A)None | 0.92A | 1oniG-5anbF:undetectable1oniI-5anbF:undetectable | 1oniG-5anbF:20.911oniI-5anbF:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp8 | ENT-COPALYLDIPHOSPHATE SYNTHASE (Streptomycesplatensis) |
PF00432(Prenyltrans)PF13243(SQHop_cyclase_C) | 4 | ILE A 512PRO A 508GLU A 455PHE A 267 | None | 1.07A | 1oniG-5bp8A:undetectable1oniI-5bp8A:undetectable | 1oniG-5bp8A:15.371oniI-5bp8A:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ch6 | FRIGIDA (Vitis vinifera) |
PF07899(Frigida) | 4 | TYR A 346ILE A 373PHE A 319ALA A 349 | None | 1.06A | 1oniG-5ch6A:undetectable1oniI-5ch6A:undetectable | 1oniG-5ch6A:19.861oniI-5ch6A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey5 | LBCATS-A (syntheticconstruct) |
PF00290(Trp_syntA) | 4 | ILE A 236PRO A 21ARG A 261ALA A 45 | None | 1.08A | 1oniG-5ey5A:undetectable1oniI-5ey5A:undetectable | 1oniG-5ey5A:22.751oniI-5ey5A:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5o | NUCLEOPROTEIN (Marburgmarburgvirus) |
PF05505(Ebola_NP) | 4 | ILE A 191PHE A 72ARG A 82ALA A 78 | None | 1.11A | 1oniG-5f5oA:undetectable1oniI-5f5oA:undetectable | 1oniG-5f5oA:18.091oniI-5f5oA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | PUTATIVE LIPOPROTEINSUSC/RAGA FAMILYTONB-LINKED OUTERMEMBRANE PROTEIN (Bacteroidesthetaiotaomicron;Bacteroidesthetaiotaomicron) |
PF12771(SusD-like_2)PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | ILE B 614PRO A 235PHE A 226ALA A 31 | None | 0.75A | 1oniG-5fq6B:undetectable1oniI-5fq6B:undetectable | 1oniG-5fq6B:10.581oniI-5fq6B:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h8w | ATP-DEPENDENT DNAHELICASE TA0057 (Thermoplasmaacidophilum) |
PF06733(DEAD_2)PF06777(HBB)PF13307(Helicase_C_2) | 4 | ILE A 68PRO A 84GLU A 64ALA A 151 | None | 1.12A | 1oniG-5h8wA:undetectable1oniI-5h8wA:undetectable | 1oniG-5h8wA:15.151oniI-5h8wA:15.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kn5 | EPIREGULIN ANTIBODYLY3016859 FAB HEAVYCHAINPROTRANSFORMINGGROWTH FACTOR ALPHA (Homo sapiens;Homo sapiens) |
PF07654(C1-set)PF07686(V-set)PF00008(EGF) | 4 | ILE A 57PRO A 55ARG C 22ALA C 31 | None | 0.86A | 1oniG-5kn5A:undetectable1oniI-5kn5A:undetectable | 1oniG-5kn5A:24.061oniI-5kn5A:24.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m3c | DIGUANYLATE CYCLASE (Pseudomonasaeruginosa) |
no annotation | 4 | ILE A1158PHE A1203ARG A1177ALA A1173 | None | 1.05A | 1oniG-5m3cA:undetectable1oniI-5m3cA:undetectable | 1oniG-5m3cA:undetectable1oniI-5m3cA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n8n | EVPB FAMILY TYPE VISECRETION PROTEIN (Pseudomonasaeruginosa) |
no annotation | 4 | ILE B 337PRO B 352GLU B 342ALA B 346 | None | 1.06A | 1oniG-5n8nB:undetectable1oniI-5n8nB:undetectable | 1oniG-5n8nB:undetectable1oniI-5n8nB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nlm | INDOXYLUDP-GLUCOSYLTRANSFERASE (Persicariatinctoria) |
no annotation | 4 | ILE A 248PRO A 246PHE A 220ALA A 452 | None | 0.89A | 1oniG-5nlmA:undetectable1oniI-5nlmA:undetectable | 1oniG-5nlmA:undetectable1oniI-5nlmA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ods | CLATHRIN HEAVY CHAIN1 (Mus musculus) |
no annotation | 4 | ILE A 391PRO A 388GLU A 361ALA A 358 | None | 1.10A | 1oniG-5odsA:undetectable1oniI-5odsA:undetectable | 1oniG-5odsA:undetectable1oniI-5odsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uni | NAD(P)TRANSHYDROGENASESUBUNIT BETA (Thermusthermophilus) |
PF02233(PNTB) | 4 | ILE B 99GLU B 221PHE B 109ALA B 118 | NoneNoneBEN B 310 ( 4.2A)None | 1.01A | 1oniG-5uniB:undetectable1oniI-5uniB:undetectable | 1oniG-5uniB:19.171oniI-5uniB:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur2 | BIFUNCTIONAL PROTEINPUTA (Bdellovibriobacteriovorus) |
PF00171(Aldedh)PF01619(Pro_dh) | 4 | ILE A 343PRO A 348PHE A 350ALA A 336 | None | 1.03A | 1oniG-5ur2A:undetectable1oniI-5ur2A:undetectable | 1oniG-5ur2A:10.161oniI-5ur2A:10.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur2 | BIFUNCTIONAL PROTEINPUTA (Bdellovibriobacteriovorus) |
PF00171(Aldedh)PF01619(Pro_dh) | 4 | ILE A 807PRO A 857PHE A 844ALA A 802 | None | 1.08A | 1oniG-5ur2A:undetectable1oniI-5ur2A:undetectable | 1oniG-5ur2A:10.161oniI-5ur2A:10.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5v4d | PUTATIVETRANSLATIONALINHIBITOR PROTEIN (Yersinia pestis) |
PF01042(Ribonuc_L-PSP) | 4 | TYR A 17ILE A 33PRO A 113GLU A 119 | None | 0.35A | 1oniG-5v4dA:24.21oniI-5v4dA:23.8 | 1oniG-5v4dA:45.381oniI-5v4dA:45.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vad | BIFUNCTIONALGLUTAMATE/PROLINE--TRNA LIGASE (Homo sapiens) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF09180(ProRS-C_1) | 4 | TYR A1127ILE A1142PHE A1078ALA A1129 | None | 1.07A | 1oniG-5vadA:undetectable1oniI-5vadA:undetectable | 1oniG-5vadA:15.481oniI-5vadA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vvh | OCTOPINECATABOLISM/UPTAKEOPERON REGULATORYPROTEIN OCCR (Agrobacteriumtumefaciens) |
PF03466(LysR_substrate) | 4 | ILE A 210PRO A 182PHE A 254ALA A 206 | None | 1.08A | 1oniG-5vvhA:undetectable1oniI-5vvhA:undetectable | 1oniG-5vvhA:22.861oniI-5vvhA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w4x | UDP-GLUCOSE6-DEHYDROGENASE (Homo sapiens) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | ILE A 52PRO A 18GLU A 54ALA A 168 | None | 1.12A | 1oniG-5w4xA:undetectable1oniI-5w4xA:undetectable | 1oniG-5w4xA:14.771oniI-5w4xA:14.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y31 | DISINTEGRIN ANDMETALLOPROTEINASEDOMAIN-CONTAININGPROTEIN 22 (Homo sapiens) |
no annotation | 4 | TYR A 422ILE A 241PHE A 414ALA A 375 | None | 1.10A | 1oniG-5y31A:undetectable1oniI-5y31A:undetectable | 1oniG-5y31A:undetectable1oniI-5y31A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6e85 | - (-) |
no annotation | 4 | TYR A 266PRO A 247PHE A 251ALA A 207 | NoneNoneFMT A 402 (-4.8A)None | 1.05A | 1oniG-6e85A:2.51oniI-6e85A:undetectable | 1oniG-6e85A:undetectable1oniI-6e85A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gng | - (-) |
no annotation | 4 | ILE A 495PRO A 430PHE A 353ALA A 363 | None | 1.12A | 1oniG-6gngA:undetectable1oniI-6gngA:undetectable | 1oniG-6gngA:undetectable1oniI-6gngA:undetectable |