SIMILAR PATTERNS OF AMINO ACIDS FOR 1ONI_G_BEZG513
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1abr | ABRIN-A (Abrusprecatorius) |
PF00161(RIP) | 4 | PHE A 185ILE A 192PRO A 187GLU A 195 | None | 1.35A | 1oniG-1abrA:0.01oniH-1abrA:0.0 | 1oniG-1abrA:21.031oniH-1abrA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cf5 | PROTEIN(BETA-MOMORCHARIN) (Momordicacharantia) |
PF00161(RIP) | 4 | PHE A 177ILE A 184PRO A 179GLU A 187 | None | 1.29A | 1oniG-1cf5A:0.01oniH-1cf5A:0.0 | 1oniG-1cf5A:20.081oniH-1cf5A:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpl | RP2 LIPASE (Cavia porcellus) |
PF00151(Lipase)PF01477(PLAT) | 4 | PHE A 11ARG A 164ILE A 34GLU A 127 | None | 1.38A | 1oniG-1gplA:0.81oniH-1gplA:0.7 | 1oniG-1gplA:16.671oniH-1gplA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iqp | RFCS (Pyrococcusfuriosus) |
PF00004(AAA)PF08542(Rep_fac_C) | 4 | PHE A 228ILE A 239PRO A 236GLU A 279 | None | 1.49A | 1oniG-1iqpA:0.01oniH-1iqpA:0.0 | 1oniG-1iqpA:17.991oniH-1iqpA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1llp | LIGNIN PEROXIDASE (Phanerochaetechrysosporium) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 4 | PHE A 62ILE A 77PRO A 138GLU A 78 | NoneNoneNone CA A 351 ( 4.5A) | 1.47A | 1oniG-1llpA:0.01oniH-1llpA:0.0 | 1oniG-1llpA:18.921oniH-1llpA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qd1 | FORMIMINOTRANSFERASE-CYCLODEAMINASE (Sus scrofa) |
PF02971(FTCD)PF07837(FTCD_N) | 4 | PHE A 241ILE A 322PRO A 274GLU A 323 | None | 1.19A | 1oniG-1qd1A:2.51oniH-1qd1A:2.4 | 1oniG-1qd1A:19.941oniH-1qd1A:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qnr | ENDO-1,4-B-D-MANNANASE (Trichodermareesei) |
PF00150(Cellulase) | 4 | PHE A 58ILE A 107PRO A 109GLU A 165 | None | 1.50A | 1oniG-1qnrA:0.01oniH-1qnrA:0.0 | 1oniG-1qnrA:17.631oniH-1qnrA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w27 | PHENYLALANINEAMMONIA-LYASE 1 (Petroselinumcrispum) |
PF00221(Lyase_aromatic) | 4 | ARG A 376ILE A 405PRO A 404GLU A 377 | None | 1.15A | 1oniG-1w27A:0.01oniH-1w27A:0.0 | 1oniG-1w27A:12.301oniH-1w27A:12.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g17 | N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATEREDUCTASE (Salmonellaenterica) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | ARG A 213ILE A 218PRO A 156GLU A 217 | SO4 A 410 (-3.0A)NoneNoneNone | 1.00A | 1oniG-2g17A:0.01oniH-2g17A:0.0 | 1oniG-2g17A:19.531oniH-2g17A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j66 | BTRK (Bacilluscirculans) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | PHE A 145ILE A 139PRO A 141GLU A 163 | None | 1.10A | 1oniG-2j66A:1.71oniH-2j66A:undetectable | 1oniG-2j66A:16.461oniH-2j66A:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jcs | DEOXYNUCLEOSIDEKINASE (Drosophilamelanogaster) |
PF01712(dNK) | 4 | PHE A 114ARG A 105ILE A 164GLU A 172 | TTP A1210 (-3.5A)TTP A1210 (-3.7A)NoneTTP A1210 (-3.6A) | 1.42A | 1oniG-2jcsA:undetectable1oniH-2jcsA:undetectable | 1oniG-2jcsA:17.671oniH-2jcsA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jh9 | VP4 CORE PROTEIN (Bluetonguevirus) |
PF05059(Orbi_VP4) | 4 | PHE A 170ARG A 378ILE A 166PRO A 158 | None | 1.30A | 1oniG-2jh9A:undetectable1oniH-2jh9A:undetectable | 1oniG-2jh9A:12.851oniH-2jh9A:12.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qn0 | NEUROTOXIN (Clostridiumbotulinum) |
PF01742(Peptidase_M27) | 4 | ARG A 372ILE A 194PRO A 168GLU A 230 | NoneNoneNone ZN A 431 ( 4.0A) | 1.42A | 1oniG-2qn0A:undetectable1oniH-2qn0A:undetectable | 1oniG-2qn0A:16.621oniH-2qn0A:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2van | DNA POLYMERSE BETA (Rattusnorvegicus) |
PF10391(DNA_pol_lambd_f)PF14791(DNA_pol_B_thumb)PF14792(DNA_pol_B_palm) | 4 | PHE A 278ARG A 328ILE A 319GLU A 316 | None | 1.30A | 1oniG-2vanA:undetectable1oniH-2vanA:undetectable | 1oniG-2vanA:22.441oniH-2vanA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w55 | XANTHINEDEHYDROGENASE (Rhodobactercapsulatus) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 4 | PHE B 733ARG B 269ILE B 698GLU B 678 | None | 1.10A | 1oniG-2w55B:1.11oniH-2w55B:undetectable | 1oniG-2w55B:11.341oniH-2w55B:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3auf | GLYCINAMIDERIBONUCLEOTIDETRANSFORMYLASE 1 (Symbiobacteriumtoebii) |
PF00551(Formyl_trans_N) | 4 | ARG A 167ILE A 108PRO A 110GLU A 174 | None | 1.37A | 1oniG-3aufA:undetectable1oniH-3aufA:undetectable | 1oniG-3aufA:21.551oniH-3aufA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bww | PROTEIN OF UNKNOWNFUNCTIONDUF692/COG3220 (Histophilussomni) |
PF05114(DUF692) | 4 | PHE A 91ILE A 37PRO A 33GLU A 34 | None | 1.10A | 1oniG-3bwwA:undetectable1oniH-3bwwA:undetectable | 1oniG-3bwwA:20.071oniH-3bwwA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cjp | PREDICTEDAMIDOHYDROLASE,DIHYDROOROTASEFAMILY (Clostridiumacetobutylicum) |
PF04909(Amidohydro_2) | 4 | PHE A 230ILE A 12PRO A 229GLU A 40 | None | 1.29A | 1oniG-3cjpA:undetectable1oniH-3cjpA:undetectable | 1oniG-3cjpA:21.051oniH-3cjpA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmn | PUTATIVE HYDROLASE (Chloroflexusaurantiacus) |
PF10103(Zincin_2) | 4 | ARG A 67ILE A 189PRO A 187GLU A 186 | None | 1.48A | 1oniG-3cmnA:undetectable1oniH-3cmnA:undetectable | 1oniG-3cmnA:17.381oniH-3cmnA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ezo | MALONYL COA-ACYLCARRIER PROTEINTRANSACYLASE (Burkholderiapseudomallei) |
PF00698(Acyl_transf_1) | 4 | PHE A 158ARG A 141ILE A 229PRO A 251 | None | 1.49A | 1oniG-3ezoA:undetectable1oniH-3ezoA:undetectable | 1oniG-3ezoA:22.951oniH-3ezoA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h35 | UNCHARACTERIZEDPROTEIN ABO_0056 (Alcanivoraxborkumensis) |
no annotation | 4 | PHE A 122ARG A 127ILE A 155GLU A 134 | None | 1.23A | 1oniG-3h35A:undetectable1oniH-3h35A:undetectable | 1oniG-3h35A:25.001oniH-3h35A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iwt | 178AA LONGHYPOTHETICALMOLYBDENUM COFACTORBIOSYNTHESIS PROTEINB (Sulfurisphaeratokodaii) |
PF00994(MoCF_biosynth) | 4 | ARG A 27ILE A 44PRO A 154GLU A 40 | None | 1.46A | 1oniG-3iwtA:0.91oniH-3iwtA:0.9 | 1oniG-3iwtA:22.701oniH-3iwtA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j2s | COAGULATION FACTORVIII LIGHT CHAIN (Homo sapiens) |
PF00754(F5_F8_type_C)PF07731(Cu-oxidase_2) | 4 | ARG B1764ILE B1700PRO B1761GLU B1737 | None | 1.25A | 1oniG-3j2sB:undetectable1oniH-3j2sB:undetectable | 1oniG-3j2sB:13.181oniH-3j2sB:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxw | SAFRAMYCIN MX1SYNTHETASE B (Legionellapneumophila) |
PF00501(AMP-binding) | 4 | ARG A 560ILE A 471PRO A 468GLU A 472 | None | 1.10A | 1oniG-3kxwA:undetectable1oniH-3kxwA:undetectable | 1oniG-3kxwA:13.601oniH-3kxwA:13.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lqc | DNA POLYMERASE BETA (Rattusnorvegicus) |
PF14791(DNA_pol_B_thumb)PF14792(DNA_pol_B_palm) | 4 | PHE B 278ARG B 328ILE B 319GLU B 316 | None | 1.39A | 1oniG-3lqcB:undetectable1oniH-3lqcB:undetectable | 1oniG-3lqcB:24.441oniH-3lqcB:24.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nva | CTP SYNTHASE (Sulfolobussolfataricus) |
PF00117(GATase)PF06418(CTP_synth_N) | 4 | ARG A 465ILE A 312PRO A 358GLU A 513 | None | 1.27A | 1oniG-3nvaA:undetectable1oniH-3nvaA:undetectable | 1oniG-3nvaA:15.781oniH-3nvaA:15.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3u | LIGNIN PEROXIDASE (Trametopsiscervina) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 4 | PHE A 62ILE A 77PRO A 138GLU A 78 | MPD A 339 (-4.0A)NoneMPD A 339 ( 4.3A) CA A 340 ( 4.5A) | 1.45A | 1oniG-3q3uA:undetectable1oniH-3q3uA:undetectable | 1oniG-3q3uA:18.581oniH-3q3uA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qn3 | ENOLASE (Campylobacterjejuni) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | PHE A 171ARG A 233ILE A 166PRO A 168 | None | 1.46A | 1oniG-3qn3A:0.81oniH-3qn3A:undetectable | 1oniG-3qn3A:16.151oniH-3qn3A:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x1l | CRISPR SYSTEM CMRSUBUNIT CMR2 (Pyrococcusfuriosus) |
PF12469(DUF3692) | 4 | ARG A 655ILE A 289PRO A 278GLU A 292 | None | 1.30A | 1oniG-3x1lA:undetectable1oniH-3x1lA:undetectable | 1oniG-3x1lA:13.581oniH-3x1lA:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4auk | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE M (Escherichiacoli) |
PF01728(FtsJ) | 4 | PHE A 61ARG A 339ILE A 20GLU A 19 | NoneEDO A1368 (-3.5A)NoneNone | 1.48A | 1oniG-4aukA:1.11oniH-4aukA:undetectable | 1oniG-4aukA:15.631oniH-4aukA:15.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bm1 | MANGANESE PEROXIDASE4 (Pleurotusostreatus) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 4 | PHE A 63ILE A 78PRO A 139GLU A 79 | NoneNoneNone CA A 401 ( 4.5A) | 1.49A | 1oniG-4bm1A:undetectable1oniH-4bm1A:undetectable | 1oniG-4bm1A:17.861oniH-4bm1A:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f5x | RNA-DIRECTED RNAPOLYMERASE (Rotavirus A) |
PF02123(RdRP_4)PF12289(Rotavirus_VP1) | 4 | ARG W 814ILE W 471PRO W 435GLU W 390 | None | 1.06A | 1oniG-4f5xW:undetectable1oniH-4f5xW:undetectable | 1oniG-4f5xW:8.951oniH-4f5xW:8.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kxr | PPE41ESPG5 (Mycobacteriumtuberculosis;Mycobacteriumtuberculosis) |
PF00823(PPE)PF14011(ESX-1_EspG) | 4 | ARG C 109ILE B 109PRO B 8GLU B 9 | None | 1.46A | 1oniG-4kxrC:undetectable1oniH-4kxrC:undetectable | 1oniG-4kxrC:20.131oniH-4kxrC:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nox | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT B (Chaetomiumthermophilum) |
PF08662(eIF2A) | 4 | PHE A 182ARG A 175PRO A 190GLU A 622 | None | 1.31A | 1oniG-4noxA:undetectable1oniH-4noxA:undetectable | 1oniG-4noxA:11.111oniH-4noxA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8y | CRISPR SYSTEM CMRSUBUNIT CMR2 (Pyrococcusfuriosus) |
PF12469(DUF3692) | 4 | ARG A 655ILE A 289PRO A 278GLU A 292 | None | 1.28A | 1oniG-4w8yA:undetectable1oniH-4w8yA:undetectable | 1oniG-4w8yA:11.491oniH-4w8yA:11.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5awp | ISOMALTODEXTRANASE (Arthrobacterglobiformis) |
no annotation | 4 | ARG A 195ILE A 308PRO A 34GLU A 238 | None | 1.45A | 1oniG-5awpA:undetectable1oniH-5awpA:0.9 | 1oniG-5awpA:13.141oniH-5awpA:13.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp8 | ENT-COPALYLDIPHOSPHATE SYNTHASE (Streptomycesplatensis) |
PF00432(Prenyltrans)PF13243(SQHop_cyclase_C) | 4 | PHE A 267ILE A 512PRO A 508GLU A 455 | None | 1.18A | 1oniG-5bp8A:undetectable1oniH-5bp8A:undetectable | 1oniG-5bp8A:15.371oniH-5bp8A:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dd4 | TRANSCRIPTIONALREGULATOR ARAR (Bacteroidesthetaiotaomicron) |
PF00293(NUDIX) | 4 | ARG A 218ILE A 151PRO A 150GLU A 149 | None | 1.35A | 1oniG-5dd4A:undetectable1oniH-5dd4A:undetectable | 1oniG-5dd4A:21.141oniH-5dd4A:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h3c | PROTEIN SUPPRESSOROF NPR1-1,CONSTITUTIVE 1 (Arabidopsisthaliana) |
PF01582(TIR) | 4 | PHE A 27ARG A 33ILE A 52PRO A 25 | None | 1.31A | 1oniG-5h3cA:undetectable1oniH-5h3cA:undetectable | 1oniG-5h3cA:23.601oniH-5h3cA:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k5a | PARB DOMAIN PROTEINNUCLEASE (Sulfolobussolfataricus) |
PF02195(ParBc) | 4 | PHE B 223ARG B 194ILE B 201GLU B 159 | None | 1.14A | 1oniG-5k5aB:undetectable1oniH-5k5aB:undetectable | 1oniG-5k5aB:17.491oniH-5k5aB:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sv6 | EXTRACELLULARSOLUTE-BINDINGPROTEIN, FAMILY 3 (Methylophagaaminisulfidivorans) |
PF00497(SBP_bac_3) | 4 | PHE A 175ILE A 146PRO A 148GLU A 153 | None | 1.36A | 1oniG-5sv6A:undetectable1oniH-5sv6A:undetectable | 1oniG-5sv6A:19.311oniH-5sv6A:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6at7 | PHENYLALANINEAMMONIA-LYASE (Sorghum bicolor) |
no annotation | 4 | ARG A 363ILE A 392PRO A 391GLU A 364 | None | 1.15A | 1oniG-6at7A:undetectable1oniH-6at7A:undetectable | 1oniG-6at7A:undetectable1oniH-6at7A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6em0 | 2-HYDROXYBIPHENYL-3-MONOOXYGENASE (Pseudomonasnitroreducens) |
no annotation | 4 | ARG A 245ILE A 251PRO A 45GLU A 207 | None | 1.41A | 1oniG-6em0A:undetectable1oniH-6em0A:undetectable | 1oniG-6em0A:undetectable1oniH-6em0A:undetectable |