SIMILAR PATTERNS OF AMINO ACIDS FOR 1NBH_A_SAMA293_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1byr PROTEIN
(ENDONUCLEASE)

(Salmonella
enterica) 		PF13091
(PLDc_2) 		3 ARG A 152
ASP A  55
ASN A 102
 None
 0.96A 1nbhA-1byrA:
2.1		 1nbhA-1byrA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 ARG A 590
ASP A  57
ASN A  48
 None
 0.92A 1nbhA-1c30A:
4.0		 1nbhA-1c30A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgj ALDEHYDE
OXIDOREDUCTASE

(Desulfovibrio
desulfuricans) 		PF00111
(Fer2)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2) 		3 ARG A 123
ASP A 805
ASN A 800
 None
 0.77A 1nbhA-1dgjA:
2.8		 1nbhA-1dgjA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hww ALPHA-MANNOSIDASE II

(Drosophila
melanogaster) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		3 ARG A 304
ASP A 278
ASN A  67
 None
 0.95A 1nbhA-1hwwA:
undetectable		 1nbhA-1hwwA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iy9 SPERMIDINE SYNTHASE

(Bacillus
subtilis) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		3 ARG A 247
ASP A 183
ASN A 148
 None
 0.95A 1nbhA-1iy9A:
10.9		 1nbhA-1iy9A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgw BEAN POD MOTTLE
VIRUS LARGE (L)
SUBUNIT

(Bean pod mottle
virus) 		PF02247
(Como_LCP) 		3 ARG 2 240
ASP 2 321
ASN 2 270
 None
 0.87A 1nbhA-1pgw2:
undetectable		 1nbhA-1pgw2:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1px8 BETA-XYLOSIDASE

(Thermoanaerobacterium
saccharolyticum) 		PF01229
(Glyco_hydro_39) 		3 ARG A 260
ASP A 223
ASN A 192
 None
 0.88A 1nbhA-1px8A:
undetectable		 1nbhA-1px8A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qaf PROTEIN (COPPER
AMINE OXIDASE)

(Escherichia
coli) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3)
PF07833
(Cu_amine_oxidN1) 		3 ARG A  92
ASP A 329
ASN A 327
 None
 0.83A 1nbhA-1qafA:
undetectable		 1nbhA-1qafA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcj POKEWEED ANTIVIRAL
PROTEIN

(Phytolacca
americana) 		PF00161
(RIP) 		3 ARG A 241
ASP A 248
ASN A 185
 None
 0.88A 1nbhA-1qcjA:
undetectable		 1nbhA-1qcjA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qrr SULFOLIPID
BIOSYNTHESIS (SQD1)
PROTEIN

(Arabidopsis
thaliana) 		PF01370
(Epimerase) 		3 ARG A 327
ASP A 231
ASN A 228
 UPG  A 402 (-2.7A)
None
None
 0.76A 1nbhA-1qrrA:
7.3		 1nbhA-1qrrA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP2)

(Rhinovirus A;
Rhinovirus A) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 ARG 2 165
ASP 1 198
ASN 2 219
 None
 0.94A 1nbhA-1r1a2:
undetectable		 1nbhA-1r1a2:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8w GLYCEROL DEHYDRATASE

(Clostridium
butyricum) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 ARG A 659
ASP A 466
ASN A 468
 None
 0.83A 1nbhA-1r8wA:
undetectable		 1nbhA-1r8wA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5c CHITOSANASE

(Bacillus sp.
(in: Bacteria)) 		PF01270
(Glyco_hydro_8) 		3 ARG A 411
ASP A 292
ASN A 314
 None
 0.70A 1nbhA-1v5cA:
undetectable		 1nbhA-1v5cA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xkh FERRIPYOVERDINE
RECEPTOR

(Pseudomonas
aeruginosa) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ARG A 227
ASP A 417
ASN A 401
 None
 0.80A 1nbhA-1xkhA:
undetectable		 1nbhA-1xkhA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzw PURPLE ACID
PHOSPHATASE

(Ipomoea batatas) 		PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N) 		3 ARG A 183
ASP A   8
ASN A   3
 None
 0.83A 1nbhA-1xzwA:
undetectable		 1nbhA-1xzwA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yw4 SUCCINYLGLUTAMATE
DESUCCINYLASE

(Chromobacterium
violaceum) 		PF04952
(AstE_AspA) 		3 ARG A 170
ASP A  47
ASN A 242
 None
 0.68A 1nbhA-1yw4A:
undetectable		 1nbhA-1yw4A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z68 FIBROBLAST
ACTIVATION PROTEIN,
ALPHA SUBUNIT

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		3 ARG A 311
ASP A 228
ASN A 190
 None
 0.92A 1nbhA-1z68A:
undetectable		 1nbhA-1z68A:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2akj FERREDOXIN--NITRITE
REDUCTASE,
CHLOROPLAST

(Spinacia
oleracea) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 ARG A 351
ASP A 196
ASN A 202
 None
 0.95A 1nbhA-2akjA:
undetectable		 1nbhA-2akjA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2atc ASPARTATE
CARBAMOYLTRANSFERASE
, CATALYTIC CHAIN

(Escherichia
coli) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 ARG A 113
ASP A  19
ASN A  21
 None
 0.84A 1nbhA-2atcA:
4.6		 1nbhA-2atcA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oz8 MLL7089 PROTEIN

(Mesorhizobium
japonicum) 		PF13378
(MR_MLE_C) 		3 ARG A  17
ASP A 194
ASN A 246
 None
 0.80A 1nbhA-2oz8A:
undetectable		 1nbhA-2oz8A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rmp MUCOROPEPSIN

(Rhizomucor
miehei) 		PF00026
(Asp) 		3 ARG A 230
ASP A 212
ASN A 140
 None
 0.95A 1nbhA-2rmpA:
undetectable		 1nbhA-2rmpA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x2i ALPHA-1,4-GLUCAN
LYASE ISOZYME 1

(Gracilariopsis
lemaneiformis) 		PF01055
(Glyco_hydro_31) 		3 ARG A 643
ASP A 900
ASN A1027
 None
GOL  A1541 (-3.5A)
None
 0.93A 1nbhA-2x2iA:
undetectable		 1nbhA-2x2iA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxq ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Bifidobacterium
longum) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		3 ARG A 549
ASP A 496
ASN A 927
 None
 0.94A 1nbhA-2zxqA:
undetectable		 1nbhA-2zxqA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a27 UNCHARACTERIZED
PROTEIN MJ1557

(Methanocaldococcus
jannaschii) 		PF02475
(Met_10) 		3 ARG A  89
ASP A 102
ASN A 155
 None
None
SAM  A 250 (-3.6A)
 0.90A 1nbhA-3a27A:
14.5		 1nbhA-3a27A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ak5 HEMOGLOBIN-BINDING
PROTEASE HBP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		3 ARG A 192
ASP A 106
ASN A 131
 None
 0.89A 1nbhA-3ak5A:
undetectable		 1nbhA-3ak5A:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b0h NITRITE REDUCTASE

(Nicotiana
tabacum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 ARG A 351
ASP A 196
ASN A 202
 None
 0.94A 1nbhA-3b0hA:
undetectable		 1nbhA-3b0hA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ed4 ARYLSULFATASE

(Escherichia
coli) 		PF00884
(Sulfatase) 		3 ARG A 345
ASP A  51
ASN A 170
 None
NA  A 519 (-3.3A)
None
 0.87A 1nbhA-3ed4A:
undetectable		 1nbhA-3ed4A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fah ALDEHYDE
OXIDOREDUCTASE

(Desulfovibrio
gigas) 		PF00111
(Fer2)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2) 		3 ARG A 123
ASP A 805
ASN A 800
 None
 0.81A 1nbhA-3fahA:
undetectable		 1nbhA-3fahA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhh OUTER MEMBRANE HEME
RECEPTOR SHUA

(Shigella
dysenteriae) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ARG A 104
ASP A 524
ASN A 554
 None
 0.88A 1nbhA-3fhhA:
undetectable		 1nbhA-3fhhA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3grh ACYL-COA THIOESTER
HYDROLASE YBGC

(Escherichia
coli) 		PF01095
(Pectinesterase) 		3 ARG A 387
ASP A 268
ASN A 215
 None
 0.88A 1nbhA-3grhA:
undetectable		 1nbhA-3grhA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h5c PROTEIN Z-DEPENDENT
PROTEASE INHIBITOR
VITAMIN K-DEPENDENT
PROTEIN Z

(Homo sapiens;
Homo sapiens) 		PF00079
(Serpin)
PF00008
(EGF)
PF00089
(Trypsin)
PF14670
(FXa_inhibition) 		3 ARG B  93
ASP A 238
ASN A 419
 None
 0.77A 1nbhA-3h5cB:
undetectable		 1nbhA-3h5cB:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbx GLUTAMATE
DECARBOXYLASE 1

(Arabidopsis
thaliana) 		PF00282
(Pyridoxal_deC) 		3 ARG A  29
ASP A  53
ASN A  59
 None
 0.92A 1nbhA-3hbxA:
2.4		 1nbhA-3hbxA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhm NISH2 P85ALPHA

(Homo sapiens) 		PF00017
(SH2)
PF16454
(PI3K_P85_iSH2) 		3 ARG B 348
ASP B 578
ASN B 453
 None
 0.73A 1nbhA-3hhmB:
undetectable		 1nbhA-3hhmB:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hje 704AA LONG
HYPOTHETICAL
GLYCOSYLTRANSFERASE

(Sulfurisphaera
tokodaii) 		PF00128
(Alpha-amylase)
PF09196
(DUF1953) 		3 ARG A 343
ASP A 115
ASN A 112
 None
 0.88A 1nbhA-3hjeA:
2.1		 1nbhA-3hjeA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjr EXTRACELLULAR SERINE
PROTEASE

(Aeromonas
sobria) 		PF00082
(Peptidase_S8)
PF01483
(P_proprotein) 		3 ARG A 362
ASP A 197
ASN A 189
 None
 0.91A 1nbhA-3hjrA:
2.1		 1nbhA-3hjrA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hxw ALANYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF01411
(tRNA-synt_2c) 		3 ARG A 311
ASP A 285
ASN A 253
 None
 0.71A 1nbhA-3hxwA:
undetectable		 1nbhA-3hxwA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j04 MYOSIN-11
MYOSIN LIGHT
POLYPEPTIDE 6

(Gallus gallus;
Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N)
PF13405
(EF-hand_6) 		3 ARG A 731
ASP C  96
ASN C 139
 None
 0.90A 1nbhA-3j04A:
undetectable		 1nbhA-3j04A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j1c CHAPERONIN ALPHA
SUBUNIT

(Acidianus
tengchongensis) 		PF00118
(Cpn60_TCP1) 		3 ARG A 406
ASP A  93
ASN A  61
 None
 0.85A 1nbhA-3j1cA:
undetectable		 1nbhA-3j1cA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		3 ARG X 795
ASP X 909
ASN X 903
 None
 0.68A 1nbhA-3jb9X:
undetectable		 1nbhA-3jb9X:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k6r PUTATIVE TRANSFERASE
PH0793

(Pyrococcus
horikoshii) 		PF02475
(Met_10) 		3 ARG A 118
ASP A 131
ASN A 184
 None
 0.78A 1nbhA-3k6rA:
14.7		 1nbhA-3k6rA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3keh GLUCOCEREBROSIDASE

(Homo sapiens) 		PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C) 		3 ARG A 285
ASP A 445
ASN A 462
 None
 0.96A 1nbhA-3kehA:
undetectable		 1nbhA-3kehA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3llc PUTATIVE HYDROLASE

(Agrobacterium
vitis) 		PF12697
(Abhydrolase_6) 		3 ARG A  22
ASP A 100
ASN A 132
 None
None
EDO  A 273 (-4.1A)
 0.94A 1nbhA-3llcA:
2.0		 1nbhA-3llcA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nyo G PROTEIN-COUPLED
RECEPTOR KINASE 6

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		3 ARG A 440
ASP A 301
ASN A 242
 None
None
SO4  A 582 (-3.7A)
 0.66A 1nbhA-3nyoA:
undetectable		 1nbhA-3nyoA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00365
(PFK) 		3 ARG B 867
ASP B 492
ASN B 214
 None
 0.93A 1nbhA-3o8oB:
2.9		 1nbhA-3o8oB:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron) 		PF01494
(FAD_binding_3) 		3 ARG A  54
ASP A 136
ASN A 155
 None
 0.90A 1nbhA-3p9uA:
3.3		 1nbhA-3p9uA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pps LACCASE

(Thielavia
arenaria) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 344
ASP A  19
ASN A  16
 None
 0.95A 1nbhA-3ppsA:
undetectable		 1nbhA-3ppsA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ro2 G-PROTEIN-SIGNALING
MODULATOR 2
PEPTIDE OF NUCLEAR
MITOTIC APPARATUS
PROTEIN 1

(Mus musculus;
Homo sapiens) 		PF13176
(TPR_7)
PF13424
(TPR_12)
no annotation 		3 ARG A 221
ASP B2005
ASN B2008
 None
 0.89A 1nbhA-3ro2A:
undetectable		 1nbhA-3ro2A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s3f TYROSINE-PROTEIN
PHOSPHATASE 10D

(Drosophila
melanogaster) 		PF00102
(Y_phosphatase) 		3 ARG A 193
ASP A 128
ASN A  70
 None
 0.80A 1nbhA-3s3fA:
undetectable		 1nbhA-3s3fA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT

(Campylobacter
jejuni) 		PF02091
(tRNA-synt_2e) 		3 ARG A 261
ASP A  61
ASN A  67
 None
ATP  A 288 (-3.7A)
None
 0.68A 1nbhA-3ufgA:
undetectable		 1nbhA-3ufgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzu OUTER MEMBRANE
PROTEIN

(Neisseria
meningitidis) 		PF00267
(Porin_1) 		3 ARG X  91
ASP X 104
ASN X 107
 None
ANP  X 401 (-4.0A)
None
 0.91A 1nbhA-3vzuX:
undetectable		 1nbhA-3vzuX:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wjp HYDROGENASE
EXPRESSION/FORMATION
PROTEIN HYPE

(Thermococcus
kodakarensis) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		3 ARG A 236
ASP A  43
ASN A  83
 None
MG  A 404 ( 3.1A)
None
 0.78A 1nbhA-3wjpA:
undetectable		 1nbhA-3wjpA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wxo CATALASE-PEROXIDASE

(Synechococcus
elongatus) 		PF00141
(peroxidase) 		3 ARG A 106
ASP A 573
ASN A 577
 None
 0.93A 1nbhA-3wxoA:
undetectable		 1nbhA-3wxoA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aie GLUCAN
1,6-ALPHA-GLUCOSIDAS
E

(Lactobacillus
acidophilus) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 ARG A 382
ASP A 272
ASN A 268
 None
 0.90A 1nbhA-4aieA:
undetectable		 1nbhA-4aieA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ajt PROTEIN Z-DEPENDENT
PROTEASE INHIBITOR

(Mus musculus) 		PF00079
(Serpin) 		3 ARG A  71
ASP A 263
ASN A 310
 None
 0.94A 1nbhA-4ajtA:
undetectable		 1nbhA-4ajtA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4awe ENDO-BETA-D-1,4-MANN
ANASE

(Neurospora
sitophila) 		PF00150
(Cellulase) 		3 ARG A 310
ASP A 359
ASN A 356
 None
CL  A1394 ( 4.5A)
None
 0.84A 1nbhA-4aweA:
undetectable		 1nbhA-4aweA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7p RALF

(Legionella
pneumophila) 		PF01369
(Sec7) 		3 ARG A 293
ASP A  60
ASN A  69
 None
 0.95A 1nbhA-4c7pA:
undetectable		 1nbhA-4c7pA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eay MANNONATE
DEHYDRATASE

(Escherichia
coli) 		PF03786
(UxuA) 		3 ARG A 239
ASP A 320
ASN A 318
 None
 0.90A 1nbhA-4eayA:
undetectable		 1nbhA-4eayA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4epa PESTICIN RECEPTOR

(Yersinia pestis) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ARG A 176
ASP A 192
ASN A 185
 None
 0.79A 1nbhA-4epaA:
undetectable		 1nbhA-4epaA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4h GLUTAMINE DEPENDENT
NAD+ SYNTHETASE

(Burkholderia
thailandensis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		3 ARG A 530
ASP A 500
ASN A  99
 None
 0.81A 1nbhA-4f4hA:
3.8		 1nbhA-4f4hA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f5x RNA-DIRECTED RNA
POLYMERASE

(Rotavirus A) 		PF02123
(RdRP_4)
PF12289
(Rotavirus_VP1) 		3 ARG W 723
ASP W 632
ASN W 604
 None
 0.94A 1nbhA-4f5xW:
undetectable		 1nbhA-4f5xW:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4il5 CYSTEINE SYNTHASE

(Entamoeba
histolytica) 		PF00291
(PALP) 		3 ARG A  10
ASP A  59
ASN A  88
 None
LLP  A  58 ( 4.7A)
LLP  A  58 (-3.9A)
 0.77A 1nbhA-4il5A:
3.0		 1nbhA-4il5A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l87 SERINE--TRNA LIGASE,
CYTOPLASMIC

(Homo sapiens) 		PF00587
(tRNA-synt_2b)
PF02403
(Seryl_tRNA_N) 		3 ARG A 317
ASP A 378
ASN A 363
 PO4  A 502 ( 3.8A)
MG  A 503 (-3.9A)
None
 0.96A 1nbhA-4l87A:
undetectable		 1nbhA-4l87A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4le4 BETA-GLUCANASE

(Podospora
anserina) 		no annotation 3 ARG A 131
ASP A 241
ASN A  63
 None
 0.80A 1nbhA-4le4A:
undetectable		 1nbhA-4le4A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]

(Synechocystis
sp. PCC 6803) 		PF02347
(GDC-P) 		3 ARG A 968
ASP A 853
ASN A 920
 CME  A 974 ( 4.3A)
None
None
 0.81A 1nbhA-4lglA:
3.9		 1nbhA-4lglA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0t U4/U6
SNRNA-ASSOCIATED-SPL
ICING FACTOR PRP24

(Saccharomyces
cerevisiae) 		PF00076
(RRM_1)
PF16842
(RRM_occluded) 		3 ARG A  38
ASP A 321
ASN A 353
 G  B  50 ( 3.6A)
A  B  51 ( 3.4A)
None
 0.91A 1nbhA-4n0tA:
undetectable		 1nbhA-4n0tA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tnb G PROTEIN-COUPLED
RECEPTOR KINASE 5

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		3 ARG A 388
ASP A 270
ASN A 267
 None
SGV  A 601 (-4.2A)
None
 0.91A 1nbhA-4tnbA:
undetectable		 1nbhA-4tnbA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uhi STEROL 14-ALPHA
DEMETHYLASE

(Homo sapiens) 		PF00067
(p450) 		3 ARG A 501
ASP A 330
ASN A 422
 None
 0.83A 1nbhA-4uhiA:
undetectable		 1nbhA-4uhiA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xee NEUROTENSIN RECEPTOR
TYPE 1, ENDOLYSIN
CHIMERA

(Rattus
norvegicus;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		3 ARG A 299
ASP A1010
ASN A1144
 None
 0.96A 1nbhA-4xeeA:
undetectable		 1nbhA-4xeeA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xz7 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
suis) 		PF01841
(Transglut_core) 		3 ARG A 173
ASP A 127
ASN A 101
 None
 0.96A 1nbhA-4xz7A:
undetectable		 1nbhA-4xz7A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a01 O-GLYCOSYLTRANSFERAS
E

(Drosophila
melanogaster) 		PF13374
(TPR_10)
PF13414
(TPR_11)
PF13844
(Glyco_transf_41) 		3 ARG A 530
ASP A 459
ASN A 454
 None
 0.90A 1nbhA-5a01A:
3.4		 1nbhA-5a01A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bp9 PUTATIVE
METHYLTRANSFERASE
PROTEIN

(Bacteroides
fragilis) 		PF13489
(Methyltransf_23) 		3 ARG A  64
ASP A 109
ASN A 130
 SAH  A 303 (-3.1A)
SAH  A 303 (-2.7A)
SAH  A 303 (-3.0A)
 0.36A 1nbhA-5bp9A:
13.0		 1nbhA-5bp9A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq9 UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		PF12252
(SidE) 		3 ARG A 373
ASP A 351
ASN A 347
 None
 0.87A 1nbhA-5bq9A:
undetectable		 1nbhA-5bq9A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu1 LPG1496

(Legionella
pneumophila) 		PF12252
(SidE) 		3 ARG A 373
ASP A 351
ASN A 347
 None
 0.83A 1nbhA-5bu1A:
undetectable		 1nbhA-5bu1A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu2 LPG1496

(Legionella
pneumophila) 		PF12252
(SidE) 		3 ARG A 373
ASP A 351
ASN A 347
 None
 0.96A 1nbhA-5bu2A:
undetectable		 1nbhA-5bu2A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2i ALR1585 PROTEIN

(Nostoc sp. PCC
7120) 		PF04261
(Dyp_perox) 		3 ARG A 121
ASP A 242
ASN A 246
 None
 0.89A 1nbhA-5c2iA:
undetectable		 1nbhA-5c2iA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d04 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE

(Neisseria
meningitidis) 		PF00793
(DAHP_synth_1) 		3 ARG C 349
ASP C 286
ASN C 272
 None
 0.96A 1nbhA-5d04C:
undetectable		 1nbhA-5d04C:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dyn PUTATIVE PEPTIDASE
PUTATIVE PEPTIDASE

(Bacteroides
fragilis;
Bacteroides
fragilis) 		PF03415
(Peptidase_C11)
PF03415
(Peptidase_C11) 		3 ARG A  81
ASP B 152
ASN B 154
 None
NA  A 401 (-2.3A)
None
 0.93A 1nbhA-5dynA:
undetectable		 1nbhA-5dynA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elp NRPS/PKS PROTEIN

(Bacillus
amyloliquefaciens) 		no annotation 3 ARG C 491
ASP C  26
ASN C  32
 None
 0.82A 1nbhA-5elpC:
undetectable		 1nbhA-5elpC:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5w GLYCINE--TRNA LIGASE
ALPHA SUBUNIT

(Aquifex
aeolicus) 		PF02091
(tRNA-synt_2e) 		3 ARG A 257
ASP A  61
ASN A  67
 None
G5A  A 300 (-3.9A)
None
 0.80A 1nbhA-5f5wA:
undetectable		 1nbhA-5f5wA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbu PHOSPHOENOLPYRUVATE
SYNTHASE

(Listeria
monocytogenes) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N) 		3 ARG A 666
ASP A 391
ASN A 752
 5WP  A 901 (-2.8A)
None
None
 0.90A 1nbhA-5fbuA:
undetectable		 1nbhA-5fbuA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fzp DISPASE
AUTOLYSIS-INDUCING
PROTEIN

(Streptomyces
mobaraensis) 		no annotation 3 ARG A 132
ASP A 175
ASN A 228
 None
None
GOL  A1346 (-4.1A)
 0.81A 1nbhA-5fzpA:
undetectable		 1nbhA-5fzpA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hvf CARBOXYPEPTIDASE B2
VHH-I83

(Homo sapiens;
Vicugna pacos) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14)
PF07686
(V-set) 		3 ARG B  70
ASP B 100
ASN A 328
 None
 0.91A 1nbhA-5hvfB:
undetectable		 1nbhA-5hvfB:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihe DNA POLYMERASE II
SMALL SUBUNIT

(Pyrococcus
abyssi) 		PF00149
(Metallophos) 		3 ARG A 570
ASP A 304
ASN A 332
 None
 0.88A 1nbhA-5iheA:
undetectable		 1nbhA-5iheA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kd5 METALLOPEPTIDASE

(Bacteroides
thetaiotaomicron) 		PF13402
(Peptidase_M60)
PF17291
(M60-like_N) 		3 ARG A 758
ASP A 641
ASN A 631
 None
 0.92A 1nbhA-5kd5A:
undetectable		 1nbhA-5kd5A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5knn ALANINE--TRNA
LIGASE, CYTOPLASMIC

(Homo sapiens) 		PF01411
(tRNA-synt_2c) 		3 ARG A 326
ASP A 300
ASN A 257
 None
 0.80A 1nbhA-5knnA:
undetectable		 1nbhA-5knnA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqi CATALASE-PEROXIDASE

(Burkholderia
pseudomallei) 		PF00141
(peroxidase) 		3 ARG A 123
ASP A 599
ASN A 603
 None
 0.94A 1nbhA-5kqiA:
undetectable		 1nbhA-5kqiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw CELL DIVISION CYCLE
PROTEIN 20 HOMOLOG
MITOTIC CHECKPOINT
SERINE/THREONINE-PRO
TEIN KINASE BUB1
BETA,MITOTIC
CHECKPOINT
SERINE/THREONINE-PRO
TEIN KINASE BUB1
BETA

(Homo sapiens;
Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40)
PF08311
(Mad3_BUB1_I) 		3 ARG S  36
ASP Q 184
ASN Q 188
 None
 0.76A 1nbhA-5lcwS:
undetectable		 1nbhA-5lcwS:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5med ARACHIDONATE
15-LIPOXYGENASE

(Cyanothece sp.
PCC 8801) 		PF00305
(Lipoxygenase) 		3 ARG A 103
ASP A  85
ASN A  72
 None
 0.94A 1nbhA-5medA:
undetectable		 1nbhA-5medA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpd 26S PROTEASOME
REGULATORY SUBUNIT
RPN8

(Saccharomyces
cerevisiae) 		PF01398
(JAB)
PF13012
(MitMem_reg) 		3 ARG U 254
ASP U 243
ASN U 238
 None
 0.74A 1nbhA-5mpdU:
undetectable		 1nbhA-5mpdU:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n94 CG9323, ISOFORM A

(Drosophila
melanogaster) 		no annotation 3 ARG A 688
ASP A 654
ASN A 751
 None
 0.63A 1nbhA-5n94A:
4.8		 1nbhA-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szs SPIKE GLYCOPROTEIN

(Human
coronavirus
NL63) 		PF01600
(Corona_S1)
PF01601
(Corona_S2) 		3 ARG A 530
ASP A 393
ASN A 240
 None
NAG  A1405 ( 4.8A)
NAG  A1404 ( 1.8A)
 0.91A 1nbhA-5szsA:
undetectable		 1nbhA-5szsA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 ARG A 708
ASP A 178
ASN A 175
 None
 0.95A 1nbhA-5tf0A:
undetectable		 1nbhA-5tf0A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tg8 HEMAGGLUTININ HA1
CHAIN

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		3 ARG A  91
ASP A 298
ASN A 296
 None
 0.64A 1nbhA-5tg8A:
undetectable		 1nbhA-5tg8A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5una 7SK SNRNA
METHYLPHOSPHATE
CAPPING ENZYME

(Homo sapiens) 		PF06859
(Bin3)
PF13847
(Methyltransf_31) 		3 ARG A 433
ASP A 474
ASN A 559
 SAH  A 701 (-3.1A)
SAH  A 701 (-2.8A)
SAH  A 701 (-3.6A)
 0.77A 1nbhA-5unaA:
14.5		 1nbhA-5unaA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5

(Sus scrofa) 		PF00149
(Metallophos) 		3 ARG A 157
ASP A  52
ASN A 243
 None
FE  A 403 ( 2.7A)
None
 0.94A 1nbhA-5uq6A:
undetectable		 1nbhA-5uq6A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wy8 INTERLEUKIN-1
RECEPTOR ACCESSORY
PROTEIN-LIKE 1

(Homo sapiens) 		no annotation 3 ARG B 106
ASP B 101
ASN B  63
 None
None
NAG  B 403 (-1.9A)
 0.54A 1nbhA-5wy8B:
undetectable		 1nbhA-5wy8B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x3j GLYCOSIDE HYDROLASE
FAMILY 31

(Kribbella
flavida) 		no annotation 3 ARG A 270
ASP A 256
ASN A 215
 None
 0.87A 1nbhA-5x3jA:
undetectable		 1nbhA-5x3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwb 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Colwellia
psychrerythraea) 		PF00275
(EPSP_synthase) 		3 ARG A 387
ASP A  49
ASN A  51
 None
 0.96A 1nbhA-5xwbA:
undetectable		 1nbhA-5xwbA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yj6 DOCKERIN TYPE I
REPEAT-CONTAINING
PROTEIN

(Ruminiclostridium
thermocellum) 		no annotation 3 ARG A 375
ASP A 165
ASN A 134
 None
 0.91A 1nbhA-5yj6A:
undetectable		 1nbhA-5yj6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6blj SERINE-TRNA LIGASE

(Naegleria
fowleri) 		no annotation 3 ARG A 321
ASP A 382
ASN A 367
 None
 0.78A 1nbhA-6bljA:
undetectable		 1nbhA-6bljA:
undetectable