SIMILAR PATTERNS OF AMINO ACIDS FOR 1N4F_A_ASRA140_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bf2 ISOAMYLASE

(Pseudomonas
amyloderamosa) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 ASN A 593
ALA A 523
ASN A 541
 None
 0.75A 1n4fA-1bf2A:
0.0		 1n4fA-1bf2A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dxy D-2-HYDROXYISOCAPROA
TE DEHYDROGENASE

(Lactobacillus
casei) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 ASN A 216
ALA A 242
ASN A 246
 None
 0.68A 1n4fA-1dxyA:
undetectable		 1n4fA-1dxyA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1exh EXO-1,4-BETA-D-GLYCA
NASE

(Cellulomonas
fimi) 		PF00553
(CBM_2) 		3 ASN A  29
ALA A  82
ASN A  69
 None
 0.62A 1n4fA-1exhA:
0.0		 1n4fA-1exhA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz0 HYPOTHETICAL
TRNA/RRNA
METHYLTRANSFERASE
YJFH

(Escherichia
coli) 		PF00588
(SpoU_methylase)
PF08032
(SpoU_sub_bind) 		3 ASN A 108
ALA A 132
ASN A 135
 None
 0.78A 1n4fA-1gz0A:
0.0		 1n4fA-1gz0A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h17 FORMATE
ACETYLTRANSFERASE 1

(Escherichia
coli) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 ASN A 609
ALA A 527
ASN A 437
 None
 0.77A 1n4fA-1h17A:
0.0		 1n4fA-1h17A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1it5 PHOSPHOLIPASE A2

(Streptomyces
violaceoruber) 		PF09056
(Phospholip_A2_3) 		3 ASN A  58
ALA A  62
ASN A  27
 None
 0.83A 1n4fA-1it5A:
0.0		 1n4fA-1it5A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itk CATALASE-PEROXIDASE

(Haloarcula
marismortui) 		PF00141
(peroxidase) 		3 ASN A 227
ALA A 232
ASN A 236
 None
None
CL  A2001 (-4.2A)
 0.79A 1n4fA-1itkA:
0.0		 1n4fA-1itkA:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcl CYCLODEXTRIN
GLYCOSYLTRANSFERASE

(Bacillus
circulans) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		3 ASN A 120
ALA A 124
ASN A  62
 None
 0.70A 1n4fA-1kclA:
0.0		 1n4fA-1kclA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kyw CAFFEIC ACID
3-O-METHYLTRANSFERAS
E

(Medicago sativa) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		3 ASN A 324
ALA A 162
ASN A 155
 None
 0.74A 1n4fA-1kywA:
undetectable		 1n4fA-1kywA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mf1 ADENYLOSUCCINATE
SYNTHETASE

(Mus musculus) 		PF00709
(Adenylsucc_synt) 		3 ASN A  67
ALA A  69
ASN A 256
 None
None
AMP  A 459 (-3.9A)
 0.78A 1n4fA-1mf1A:
undetectable		 1n4fA-1mf1A:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rlm PHOSPHATASE

(Escherichia
coli) 		PF08282
(Hydrolase_3) 		3 ASN A 218
ALA A 220
ASN A 238
 GOL  A 804 ( 4.7A)
None
None
 0.72A 1n4fA-1rlmA:
undetectable		 1n4fA-1rlmA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1taf TFIID TBP ASSOCIATED
FACTOR 42
TFIID TBP ASSOCIATED
FACTOR 62

(Drosophila
melanogaster;
Drosophila
melanogaster) 		PF02291
(TFIID-31kDa)
PF02969
(TAF) 		3 ASN A  33
ALA B  48
ASN B  52
 None
 0.79A 1n4fA-1tafA:
undetectable		 1n4fA-1tafA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1un9 DIHYDROXYACETONE
KINASE

(Citrobacter
freundii) 		PF02733
(Dak1)
PF02734
(Dak2) 		3 ASN A 326
ALA A 292
ASN A 259
 None
 0.73A 1n4fA-1un9A:
undetectable		 1n4fA-1un9A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uww ENDOGLUCANASE

(Bacillus akibai) 		PF03424
(CBM_17_28) 		3 ASN A  67
ALA A 171
ASN A 108
 None
 0.79A 1n4fA-1uwwA:
undetectable		 1n4fA-1uwwA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6u ENDO-1,4-BETA-D-XYLA
NASE

(Streptomyces
olivaceoviridis) 		PF00331
(Glyco_hydro_10)
PF00652
(Ricin_B_lectin) 		3 ASN A 298
ALA A 248
ASN A 252
 None
 0.79A 1n4fA-1v6uA:
undetectable		 1n4fA-1v6uA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zem XYLITOL
DEHYDROGENASE

(Gluconobacter
oxydans) 		PF13561
(adh_short_C2) 		3 ASN A  18
ALA A  22
ASN A 235
 NAD  A2263 (-3.6A)
None
None
 0.79A 1n4fA-1zemA:
undetectable		 1n4fA-1zemA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zu4 FTSY

(Mycoplasma
mycoides) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		3 ASN A 253
ALA A 221
ASN A 218
 None
 0.78A 1n4fA-1zu4A:
undetectable		 1n4fA-1zu4A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvs MHC CLASS I ANTIGEN

(Macaca mulatta) 		PF00129
(MHC_I)
PF07654
(C1-set) 		3 ASN A  86
ALA A 139
ASN A 142
 None
 0.81A 1n4fA-1zvsA:
undetectable		 1n4fA-1zvsA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a38 TITIN

(Homo sapiens) 		PF07679
(I-set) 		3 ASN A 105
ALA A 102
ASN A 180
 None
 0.78A 1n4fA-2a38A:
undetectable		 1n4fA-2a38A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2afh NITROGENASE
MOLYBDENUM-IRON
PROTEIN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		3 ASN B  65
ALA B  67
ASN B 445
 None
 0.77A 1n4fA-2afhB:
undetectable		 1n4fA-2afhB:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cjl SECRETED CHITINASE

(Streptomyces
coelicolor) 		PF00182
(Glyco_hydro_19) 		3 ASN A 113
ALA A  97
ASN A 129
 None
 0.78A 1n4fA-2cjlA:
4.5		 1n4fA-2cjlA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0o DIOL
DEHYDRATASE-REACTIVA
TING FACTOR LARGE
SUBUNIT

(Klebsiella
oxytoca) 		PF08841
(DDR) 		3 ASN A 173
ALA A 145
ASN A 149
 None
 0.83A 1n4fA-2d0oA:
undetectable		 1n4fA-2d0oA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d16 HYPOTHETICAL PROTEIN
PH1918

(Pyrococcus
horikoshii) 		PF04008
(Adenosine_kin) 		3 ASN A  73
ALA A  48
ASN A  50
 None
 0.76A 1n4fA-2d16A:
undetectable		 1n4fA-2d16A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgj HYPOTHETICAL PROTEIN
EBHA

(Staphylococcus
aureus) 		PF01468
(GA) 		3 ASN A 202
ALA A 206
ASN A 242
 None
 0.69A 1n4fA-2dgjA:
undetectable		 1n4fA-2dgjA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ful EUKARYOTIC
TRANSLATION
INITIATION FACTOR 5

(Saccharomyces
cerevisiae) 		PF02020
(W2) 		3 ASN A 352
ALA A 305
ASN A 308
 None
 0.81A 1n4fA-2fulA:
undetectable		 1n4fA-2fulA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iyf OLEANDOMYCIN
GLYCOSYLTRANSFERASE

(Streptomyces
antibioticus) 		PF00201
(UDPGT) 		3 ASN A 133
ALA A 308
ASN A 333
 ERY  A1400 (-3.6A)
UDP  A1401 (-4.3A)
None
 0.71A 1n4fA-2iyfA:
undetectable		 1n4fA-2iyfA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lf6 EFFECTOR PROTEIN
HOPAB1

(Pseudomonas
savastanoi) 		PF16847
(AvrPtoB_bdg) 		3 ASN A 303
ALA A 307
ASN A 243
 None
 0.69A 1n4fA-2lf6A:
undetectable		 1n4fA-2lf6A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqt HYPOTHETICAL PROTEIN
SPY0176

(Streptococcus
pyogenes) 		PF00359
(PTS_EIIA_2) 		3 ASN A  78
ALA A   6
ASN A  10
 None
 0.65A 1n4fA-2oqtA:
undetectable		 1n4fA-2oqtA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13

(Homo sapiens) 		PF01852
(START) 		3 ASN A 936
ALA A1095
ASN A1099
 None
 0.82A 1n4fA-2psoA:
undetectable		 1n4fA-2psoA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qy1 PECTATE LYASE II

(Xanthomonas
campestris) 		PF00544
(Pec_lyase_C) 		3 ASN A 291
ALA A 334
ASN A 243
 None
 0.80A 1n4fA-2qy1A:
undetectable		 1n4fA-2qy1A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rs5 HUMAN RHINOVIRUS 14
COAT PROTEIN
(SUBUNIT VP2)

(Rhinovirus B) 		PF00073
(Rhv) 		3 ASN 2  30
ALA 2  28
ASN 2 194
 None
 0.83A 1n4fA-2rs52:
undetectable		 1n4fA-2rs52:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ver AFIMBRIAL ADHESIN
AFA-III
ARCINOEMBRYONIC
ANTIGEN-RELATED CELL
ADHESION MOLECULE 5

(Escherichia
coli;
Homo sapiens) 		PF04619
(Adhesin_Dr)
PF07686
(V-set) 		3 ASN A  87
ALA A  76
ASN N  42
 None
 0.81A 1n4fA-2verA:
undetectable		 1n4fA-2verA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vjh PHYCOERYTHRIN BETA
SUBUNIT

(Gloeobacter
violaceus) 		PF00502
(Phycobilisome) 		3 ASN B 144
ALA B  43
ASN B  47
 None
 0.72A 1n4fA-2vjhB:
undetectable		 1n4fA-2vjhB:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xq1 PEROXISOMAL CATALASE

(Ogataea angusta) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 ASN A 394
ALA A 398
ASN A 400
 None
 0.76A 1n4fA-2xq1A:
undetectable		 1n4fA-2xq1A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3atg GLUCANASE

(Cellulosimicrobium
cellulans) 		PF00722
(Glyco_hydro_16) 		3 ASN A  35
ALA A 211
ASN A 209
 None
None
GOL  A 262 ( 4.7A)
 0.83A 1n4fA-3atgA:
undetectable		 1n4fA-3atgA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Salmonella
enterica) 		PF00171
(Aldedh) 		3 ASN A 137
ALA A 311
ASN A 164
 NAD  A 463 (-3.3A)
None
None
 0.74A 1n4fA-3efvA:
undetectable		 1n4fA-3efvA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f41 PHYTASE

(Mitsuokella
multacida) 		PF14566
(PTPlike_phytase) 		3 ASN A 456
ALA A 516
ASN A 527
 None
 0.83A 1n4fA-3f41A:
undetectable		 1n4fA-3f41A:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fnb ACYLAMINOACYL
PEPTIDASE SMU_737

(Streptococcus
mutans) 		PF12146
(Hydrolase_4) 		3 ASN A 382
ALA A 376
ASN A  27
 None
 0.77A 1n4fA-3fnbA:
undetectable		 1n4fA-3fnbA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g67 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN

(Thermotoga
maritima) 		PF00015
(MCPsignal) 		3 ASN A 159
ALA A 137
ASN A 134
 None
 0.77A 1n4fA-3g67A:
undetectable		 1n4fA-3g67A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB11

(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF13656
(RNA_pol_L_2) 		3 ASN A 550
ALA K  46
ASN K  43
 None
 0.74A 1n4fA-3h0gA:
undetectable		 1n4fA-3h0gA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA

(Moorella
thermoacetica) 		PF03063
(Prismane) 		3 ASN A 284
ALA A 375
ASN A 377
 None
 0.65A 1n4fA-3i04A:
undetectable		 1n4fA-3i04A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9w SENSOR PROTEIN TORS

(Escherichia
coli) 		no annotation 3 ASN A  58
ALA A  62
ASN A  64
 None
 0.81A 1n4fA-3i9wA:
undetectable		 1n4fA-3i9wA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ira CONSERVED PROTEIN

(Methanosarcina
mazei) 		PF03190
(Thioredox_DsbH) 		3 ASN A  19
ALA A  67
ASN A  71
 None
 0.74A 1n4fA-3iraA:
undetectable		 1n4fA-3iraA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jau HEAVY CHAIN OF FAB
FRAGMENT VARIABLE
REGION OF ANTIBODY
D5

(Mus musculus) 		PF07686
(V-set) 		3 ASN H  28
ALA H  24
ASN H  98
 None
 0.66A 1n4fA-3jauH:
undetectable		 1n4fA-3jauH:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k5h PHOSPHORIBOSYL-AMINO
IMIDAZOLE
CARBOXYLASE

(Aspergillus
clavatus) 		PF01262
(AlaDh_PNT_C)
PF02222
(ATP-grasp) 		3 ASN A 225
ALA A 223
ASN A 231
 None
 0.64A 1n4fA-3k5hA:
undetectable		 1n4fA-3k5hA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ktn CARBOHYDRATE KINASE,
PFKB FAMILY

(Enterococcus
faecalis) 		PF00294
(PfkB) 		3 ASN A  37
ALA A 282
ASN A 304
 None
 0.81A 1n4fA-3ktnA:
undetectable		 1n4fA-3ktnA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l22 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ASN A  49
ALA A  53
ASN A 282
 None
 0.70A 1n4fA-3l22A:
undetectable		 1n4fA-3l22A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lm3 UNCHARACTERIZED
PROTEIN

(Parabacteroides
distasonis) 		PF12979
(DUF3863)
PF12980
(DUF3864) 		3 ASN A 184
ALA A 197
ASN A 242
 None
 0.64A 1n4fA-3lm3A:
undetectable		 1n4fA-3lm3A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwa ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1) 		no annotation 3 ASN B 108
ALA B 111
ASN B 621
 None
 0.82A 1n4fA-3nwaB:
undetectable		 1n4fA-3nwaB:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ssz MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME,
N-TERMINAL DOMAIN
PROTEIN

(Rhodobacteraceae
bacterium KLH11) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASN A 370
ALA A  88
ASN A 314
 SO4  A 414 (-4.8A)
None
None
 0.51A 1n4fA-3sszA:
undetectable		 1n4fA-3sszA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		3 ASN A 681
ALA A 474
ASN A 142
 None
 0.80A 1n4fA-3szeA:
undetectable		 1n4fA-3szeA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ttl POLYAMINE TRANSPORT
PROTEIN

(Pseudomonas
aeruginosa) 		PF13416
(SBP_bac_8) 		3 ASN A  83
ALA A 127
ASN A 124
 None
 0.73A 1n4fA-3ttlA:
undetectable		 1n4fA-3ttlA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzb SPHINGOSINE KINASE 1

(Homo sapiens) 		PF00781
(DAGK_cat) 		3 ASN A  22
ALA A 110
ASN A 114
 None
 0.79A 1n4fA-3vzbA:
undetectable		 1n4fA-3vzbA:
13.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3zvq LYSOZYME C

(Gallus gallus) 		PF00062
(Lys) 		3 ASN A  37
ALA A  42
ASN A  44
 None
 0.26A 1n4fA-3zvqA:
10.7		 1n4fA-3zvqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bom ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1) 		PF00606
(Glycoprotein_B)
PF17416
(Glycoprot_B_PH1)
PF17417
(Glycoprot_B_PH2) 		3 ASN A 108
ALA A 111
ASN A 621
 None
 0.79A 1n4fA-4bomA:
undetectable		 1n4fA-4bomA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4crq ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16

(Zobellia
galactanivorans) 		PF00722
(Glyco_hydro_16) 		3 ASN A  54
ALA A 225
ASN A 223
 None
 0.78A 1n4fA-4crqA:
undetectable		 1n4fA-4crqA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dfs GLYCOSIDE HYDROLASE,
FAMILY 16

(Thermotoga
petrophila) 		PF00722
(Glyco_hydro_16) 		3 ASN A  45
ALA A 227
ASN A 225
 None
 0.67A 1n4fA-4dfsA:
undetectable		 1n4fA-4dfsA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		3 ASN A  95
ALA A 175
ASN A 179
 None
 0.80A 1n4fA-4djhA:
2.5		 1n4fA-4djhA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eca L-ASPARAGINE
AMIDOHYDROLASE

(Escherichia
coli) 		PF00710
(Asparaginase) 		3 ASN A  34
ALA A  14
ASN A  55
 None
 0.79A 1n4fA-4ecaA:
undetectable		 1n4fA-4ecaA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fys AMINOPEPTIDASE N

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 ASN A 900
ALA A 904
ASN A 868
 None
 0.66A 1n4fA-4fysA:
undetectable		 1n4fA-4fysA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ita SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Synechococcus
sp. PCC 7002) 		PF00171
(Aldedh) 		3 ASN A 131
ALA A 305
ASN A 158
 NDP  A 501 (-3.2A)
None
None
 0.73A 1n4fA-4itaA:
undetectable		 1n4fA-4itaA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jn6 ACETALDEHYDE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF01118
(Semialdhyde_dh)
PF09290
(AcetDehyd-dimer) 		3 ASN B  14
ALA B 275
ASN B 277
 None
 0.82A 1n4fA-4jn6B:
undetectable		 1n4fA-4jn6B:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k1c VACUOLAR CALCIUM ION
TRANSPORTER

(Saccharomyces
cerevisiae) 		PF01699
(Na_Ca_ex) 		3 ASN A  41
ALA A  76
ASN A  80
 None
 0.82A 1n4fA-4k1cA:
undetectable		 1n4fA-4k1cA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ktp GLYCOSIDE HYDROLASE
FAMILY 65 CENTRAL
CATALYTIC

([Bacillus]
selenitireducens) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		3 ASN A 301
ALA A 305
ASN A 339
 None
 0.63A 1n4fA-4ktpA:
undetectable		 1n4fA-4ktpA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lq6 N-ACETYMURAMYL-L-ALA
NINE AMIDASE-RELATED
PROTEIN

(Mycobacterium
tuberculosis) 		PF01520
(Amidase_3) 		3 ASN A 166
ALA A  86
ASN A  90
 None
 0.75A 1n4fA-4lq6A:
undetectable		 1n4fA-4lq6A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m02 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		PF05345
(He_PIG) 		3 ASN A 519
ALA A 495
ASN A 562
 None
 0.76A 1n4fA-4m02A:
undetectable		 1n4fA-4m02A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1r CELLULASE 5

(soil metagenome) 		PF00150
(Cellulase) 		3 ASN A 257
ALA A 265
ASN A 253
 None
 0.80A 1n4fA-4m1rA:
undetectable		 1n4fA-4m1rA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7g TRYPSIN-LIKE
PROTEASE

(Saccharopolyspora
erythraea) 		PF00089
(Trypsin) 		3 ASN A 223
ALA A  33
ASN A  35
 None
 0.68A 1n4fA-4m7gA:
undetectable		 1n4fA-4m7gA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8u OLIGO-1,6-GLUCOSIDAS
E 1

(Bacillus
subtilis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 ASN A 512
ALA A 353
ASN A 537
 None
 0.83A 1n4fA-4m8uA:
undetectable		 1n4fA-4m8uA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mna LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8) 		3 ASN A 370
ALA A 391
ASN A 418
 None
 0.81A 1n4fA-4mnaA:
undetectable		 1n4fA-4mnaA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mwf ENVELOPE
GLYCOPROTEIN E2

(Hepacivirus C) 		PF01560
(HCV_NS1) 		3 ASN C 532
ALA C 499
ASN C 428
 NAG  C 711 (-1.7A)
None
None
 0.81A 1n4fA-4mwfC:
undetectable		 1n4fA-4mwfC:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nhb TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Desulfovibrio
desulfuricans) 		PF03480
(DctP) 		3 ASN A 131
ALA A 102
ASN A 319
 None
IOD  A 402 (-4.1A)
None
 0.79A 1n4fA-4nhbA:
undetectable		 1n4fA-4nhbA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ntl LIPOPROTEIN, YAEC
FAMILY

(Enterococcus
faecalis) 		PF03180
(Lipoprotein_9) 		3 ASN A  69
ALA A  86
ASN A  84
 None
 0.66A 1n4fA-4ntlA:
undetectable		 1n4fA-4ntlA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1t ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF03011
(PFEMP)
PF05424
(Duffy_binding) 		3 ASN A1911
ALA A1914
ASN A1893
 None
 0.79A 1n4fA-4p1tA:
undetectable		 1n4fA-4p1tA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pgh CAFFEIC ACID
O-METHYLTRANSFERASE

(Sorghum bicolor) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		3 ASN A 323
ALA A 159
ASN A 152
 None
 0.80A 1n4fA-4pghA:
undetectable		 1n4fA-4pghA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r94 NON-STRUCTURAL
PROTEIN NS1

(Rodent
protoparvovirus
1) 		PF12433
(PV_NSP1) 		3 ASN A  32
ALA A 177
ASN A 150
 None
 0.67A 1n4fA-4r94A:
undetectable		 1n4fA-4r94A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Pisum sativum;
Pisum sativum) 		PF00223
(PsaA_PsaB)
PF00223
(PsaA_PsaB) 		3 ASN B 641
ALA B 647
ASN A 650
 None
 0.79A 1n4fA-4rkuB:
undetectable		 1n4fA-4rkuB:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rxt SUGAR ABC
TRANSPORTER

(Agrobacterium
tumefaciens) 		PF13407
(Peripla_BP_4) 		3 ASN A 212
ALA A 241
ASN A 245
 None
 0.83A 1n4fA-4rxtA:
undetectable		 1n4fA-4rxtA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u10 POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Aggregatibacter
actinomycetemcomitans) 		PF01522
(Polysacc_deac_1) 		3 ASN A 146
ALA A 102
ASN A 106
 None
 0.80A 1n4fA-4u10A:
undetectable		 1n4fA-4u10A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb3 GLUCAN
1,6-ALPHA-GLUCOSIDAS
E

(Streptococcus
mutans) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 ASN A 492
ALA A 334
ASN A 513
 None
 0.82A 1n4fA-4xb3A:
undetectable		 1n4fA-4xb3A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgo ANOPHELES
PLASMODIUM-RESPONSIV
E LEUCINE-RICH
REPEAT PROTEIN 1B

(Anopheles
gambiae) 		PF13855
(LRR_8) 		3 ASN A 170
ALA A 186
ASN A 210
 None
 0.83A 1n4fA-4xgoA:
undetectable		 1n4fA-4xgoA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zfm PUTATIVE
6-PHOSPHO-BETA-GALAC
TOBIOSIDASE

(Geobacillus
stearothermophilus) 		PF00232
(Glyco_hydro_1) 		3 ASN A 309
ALA A 242
ASN A 239
 None
 0.81A 1n4fA-4zfmA:
undetectable		 1n4fA-4zfmA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zv9 UNCHARACTERIZED
PROTEIN

(Escherichia
coli) 		PF01738
(DLH) 		3 ASN A 268
ALA A 279
ASN A  -1
 None
 0.82A 1n4fA-4zv9A:
undetectable		 1n4fA-4zv9A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5az0 UNCHARACTERIZED
PROTEIN

(Bombyx mori) 		PF00248
(Aldo_ket_red) 		3 ASN A 132
ALA A 171
ASN A  13
 None
 0.83A 1n4fA-5az0A:
undetectable		 1n4fA-5az0A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5az4 FLAGELLAR HOOK
SUBUNIT PROTEIN

(Campylobacter
jejuni) 		PF07196
(Flagellin_IN)
PF07559
(FlaE) 		3 ASN A 248
ALA A 594
ASN A 241
 None
 0.71A 1n4fA-5az4A:
undetectable		 1n4fA-5az4A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwf DESIGNED HELICAL
REPEAT PROTEIN

(synthetic
construct) 		no annotation 3 ASN A 112
ALA A 118
ASN A  68
 None
 0.82A 1n4fA-5cwfA:
undetectable		 1n4fA-5cwfA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5esx PURINE/PYRIMIDINE
PHOSPHORIBOSYLTRANSF
ERASE

(Legionella
pneumophila) 		PF00156
(Pribosyltran) 		3 ASN A 144
ALA A 115
ASN A 119
 None
 0.74A 1n4fA-5esxA:
undetectable		 1n4fA-5esxA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fre EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF02973
(Sialidase) 		3 ASN A 152
ALA A  17
ASN A 161
 CA  A 212 (-3.3A)
None
None
 0.82A 1n4fA-5freA:
undetectable		 1n4fA-5freA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jw6 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Aspergillus
fumigatus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 ASN A  88
ALA A 110
ASN A 112
 None
 0.79A 1n4fA-5jw6A:
undetectable		 1n4fA-5jw6A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxl FLAGELLAR HOOK
PROTEIN FLGE

(Campylobacter
jejuni) 		PF00460
(Flg_bb_rod)
PF06429
(Flg_bbr_C)
PF07196
(Flagellin_IN)
PF07559
(FlaE) 		3 ASN A 247
ALA A 580
ASN A 240
 None
 0.74A 1n4fA-5jxlA:
undetectable		 1n4fA-5jxlA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxl FLAGELLAR HOOK
PROTEIN FLGE

(Campylobacter
jejuni) 		PF00460
(Flg_bb_rod)
PF06429
(Flg_bbr_C)
PF07196
(Flagellin_IN)
PF07559
(FlaE) 		3 ASN A 538
ALA A 521
ASN A 519
 None
 0.79A 1n4fA-5jxlA:
undetectable		 1n4fA-5jxlA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koh NITROGENASE FEMO
BETA SUBUNIT PROTEIN
NIFK

(Gluconacetobacter
diazotrophicus) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		3 ASN B  64
ALA B  66
ASN B 440
 None
 0.66A 1n4fA-5kohB:
undetectable		 1n4fA-5kohB:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l22 ABC TRANSPORTER
(HLYB SUBFAMILY)

(Aquifex
aeolicus) 		no annotation 3 ASN B 120
ALA B 304
ASN B 187
 None
 0.80A 1n4fA-5l22B:
undetectable		 1n4fA-5l22B:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm8 'MULTICOPPER OXIDASE

(Aspergillus
niger) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ASN A 335
ALA A 333
ASN A 303
 None
 0.83A 1n4fA-5lm8A:
undetectable		 1n4fA-5lm8A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nkz PEROXIN 22

(Ogataea angusta) 		no annotation 3 ASN D  95
ALA D  68
ASN D  72
 None
 0.77A 1n4fA-5nkzD:
undetectable		 1n4fA-5nkzD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nl6 CALPONIN DOMAIN
FAMILY PROTEIN

(Entamoeba
histolytica) 		no annotation 3 ASN A 349
ALA A 353
ASN A 277
 None
 0.57A 1n4fA-5nl6A:
undetectable		 1n4fA-5nl6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5thk PUTATIVE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF13561
(adh_short_C2) 		3 ASN A 120
ALA A 124
ASN A  95
 None
 0.75A 1n4fA-5thkA:
undetectable		 1n4fA-5thkA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5twt PEROXIDASE PVI9

(Panicum
virgatum) 		PF00141
(peroxidase) 		3 ASN A  64
ALA A 129
ASN A 133
 None
 0.74A 1n4fA-5twtA:
undetectable		 1n4fA-5twtA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4u MGC81300 PROTEIN

(Xenopus laevis) 		no annotation 3 ASN A 742
ALA A 730
ASN A 699
 None
 0.76A 1n4fA-5u4uA:
undetectable		 1n4fA-5u4uA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vbf NAD-DEPENDENT
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Burkholderia
vietnamiensis) 		PF00171
(Aldedh) 		3 ASN A 426
ALA A 419
ASN A 442
 None
 0.66A 1n4fA-5vbfA:
undetectable		 1n4fA-5vbfA:
15.61