SIMILAR PATTERNS OF AMINO ACIDS FOR 1N49_D_RITD401_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3o HYPOTHETICAL ABC
TRANSPORTER
ATP-BINDING PROTEIN
MJ0796


(Methanocaldococcus
jannaschii)
PF00005
(ABC_tran)
4 ASP A  83
GLY A  86
ILE A 167
ILE A  64
None
0.89A 1n49D-1f3oA:
undetectable
1n49D-1f3oA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fcu HYALURONOGLUCOSAMINI
DASE


(Apis mellifera)
PF01630
(Glyco_hydro_56)
4 ASN A  16
GLY A 182
ILE A 110
ILE A  51
None
0.89A 1n49D-1fcuA:
undetectable
1n49D-1fcuA:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g67 THIAMIN PHOSPHATE
SYNTHASE


(Bacillus
subtilis)
PF02581
(TMP-TENI)
4 ASP A 203
GLY A 185
ILE A 153
ILE A 228
None
0.89A 1n49D-1g67A:
undetectable
1n49D-1g67A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hcu ALPHA-1,2-MANNOSIDAS
E


(Trichoderma
reesei)
PF01532
(Glyco_hydro_47)
4 ASP A 114
GLY A 108
ILE A  59
ILE A  66
None
0.83A 1n49D-1hcuA:
undetectable
1n49D-1hcuA:
12.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
5 ASP A  29
GLY A  49
ILE A  50
PRO A  81
ILE A  84
A79  A 800 (-2.7A)
A79  A 800 (-3.4A)
A79  A 800 ( 4.0A)
A79  A 800 ( 3.4A)
A79  A 800 (-3.8A)
0.43A 1n49D-1hvcA:
13.9
1n49D-1hvcA:
47.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
5 ASP A  29
GLY A  49
ILE A  50
PRO A  81
ILE A  84
A79  A 800 (-2.8A)
A79  A 800 ( 3.7A)
A79  A 800 (-3.8A)
A79  A 800 ( 3.9A)
A79  A 800 (-3.6A)
0.41A 1n49D-1hvcA:
13.9
1n49D-1hvcA:
47.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ih5 AQUAPORIN-1

(Homo sapiens)
PF00230
(MIP)
4 ASN A 192
GLY A 173
ILE A 172
ILE A 191
None
0.93A 1n49D-1ih5A:
undetectable
1n49D-1ih5A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iwp GLYCEROL DEHYDRATASE
ALPHA SUBUNIT


(Klebsiella
pneumoniae)
PF02286
(Dehydratase_LU)
4 ASP A 372
GLY A 175
ILE A 176
ILE A 155
None
0.88A 1n49D-1iwpA:
undetectable
1n49D-1iwpA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jlx AGGLUTININ

(Amaranthus
caudatus)
PF07468
(Agglutinin)
4 ASN A 181
ASP A 226
GLY A 273
ILE A 180
None
0.89A 1n49D-1jlxA:
undetectable
1n49D-1jlxA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mld MALATE DEHYDROGENASE

(Sus scrofa)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ASN A  93
GLY A  10
ILE A  12
ILE A  96
None
0.93A 1n49D-1mldA:
undetectable
1n49D-1mldA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mld MALATE DEHYDROGENASE

(Sus scrofa)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ASN A 118
ASP A  87
GLY A 178
ILE A 181
CIT  A 375 (-3.2A)
None
None
None
0.90A 1n49D-1mldA:
undetectable
1n49D-1mldA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpt M-PROTEASE

(Bacillus
clausii)
PF00082
(Peptidase_S8)
4 ASP A  60
GLY A  70
ILE A  72
ILE A  44
None
0.93A 1n49D-1mptA:
undetectable
1n49D-1mptA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n61 CARBON MONOXIDE
DEHYDROGENASE MEDIUM
CHAIN


(Oligotropha
carboxidovorans)
PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C)
4 ASP C 124
GLY C 215
ILE C 214
ILE C  93
FAD  C3932 (-3.8A)
None
None
None
0.83A 1n49D-1n61C:
undetectable
1n49D-1n61C:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1r PUTIDAREDOXIN
REDUCTASE


(Pseudomonas
putida)
PF07992
(Pyr_redox_2)
PF14759
(Reductase_C)
4 ASP A 284
GLY A  11
ILE A   9
ILE A 266
FAD  A 749 (-2.7A)
FAD  A 749 (-3.0A)
None
None
0.86A 1n49D-1q1rA:
undetectable
1n49D-1q1rA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q50 GLUCOSE-6-PHOSPHATE
ISOMERASE


(Leishmania
mexicana)
PF00342
(PGI)
4 ASN A 381
GLY A 556
ILE A 557
ILE A 377
None
0.66A 1n49D-1q50A:
undetectable
1n49D-1q50A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rhx CONSERVED
HYPOTHETICAL PROTEIN
TM0979


(Thermotoga
maritima)
PF04077
(DsrH)
4 ASP A  54
GLY A  87
ILE A  86
PRO A  13
None
0.91A 1n49D-1rhxA:
undetectable
1n49D-1rhxA:
20.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1siv SIV PROTEASE

(Simian
immunodeficiency
virus)
PF00077
(RVP)
5 ASP A  29
GLY A  49
ILE A  50
PRO A  81
ILE A  84
None
0.33A 1n49D-1sivA:
18.8
1n49D-1sivA:
48.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1smk MALATE
DEHYDROGENASE,
GLYOXYSOMAL


(Citrullus
lanatus)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ASN A 137
GLY A  54
ILE A  56
ILE A 140
None
0.87A 1n49D-1smkA:
undetectable
1n49D-1smkA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t06 HYPOTHETICAL PROTEIN

(Bacillus cereus)
PF08713
(DNA_alkylation)
4 ASN A 176
GLY A 197
ILE A 198
ILE A 217
None
0.95A 1n49D-1t06A:
undetectable
1n49D-1t06A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tkk SIMILAR TO
CHLOROMUCONATE
CYCLOISOMERASE


(Bacillus
subtilis)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 ASP A 109
GLY A 303
ILE A 304
ILE A 275
None
0.78A 1n49D-1tkkA:
undetectable
1n49D-1tkkA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tww DHPS,
DIHYDROPTEROATE
SYNTHASE


(Bacillus
anthracis)
PF00809
(Pterin_bind)
4 ASP A 101
GLY A  24
ILE A  22
ILE A 118
HH2  A 282 (-3.4A)
None
None
None
0.90A 1n49D-1twwA:
undetectable
1n49D-1twwA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zor ISOCITRATE
DEHYDROGENASE


(Thermotoga
maritima)
PF00180
(Iso_dh)
4 ASP A 228
ILE A 185
PRO A 293
ILE A 193
None
0.83A 1n49D-1zorA:
undetectable
1n49D-1zorA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bf6 EXO-ALPHA-SIALIDASE

(Clostridium
perfringens)
PF13088
(BNR_2)
4 ASP A 335
ILE A 593
PRO A 483
ILE A 332
None
0.92A 1n49D-2bf6A:
undetectable
1n49D-2bf6A:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bih NITRATE REDUCTASE
[NADPH]


(Ogataea angusta)
PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer)
4 ASP A 129
GLY A 174
ILE A 177
ILE A 124
None
0.93A 1n49D-2bihA:
undetectable
1n49D-2bihA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d57 AQUAPORIN-4

(Rattus
norvegicus)
PF00230
(MIP)
4 ASN A 229
GLY A 209
PRO A 237
ILE A 232
None
0.85A 1n49D-2d57A:
undetectable
1n49D-2d57A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ec5 DERMONECROTIC TOXIN

(Pasteurella
multocida)
PF11647
(MLD)
4 ASP A 739
GLY A 803
ILE A 802
ILE A 734
None
0.71A 1n49D-2ec5A:
undetectable
1n49D-2ec5A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fj0 CARBOXYLIC ESTER
HYDROLASE


(Manduca sexta)
PF00135
(COesterase)
4 GLY A 352
ILE A 351
PRO A 517
ILE A 508
None
0.87A 1n49D-2fj0A:
undetectable
1n49D-2fj0A:
10.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2fmb EQUINE INFECTIOUS
ANEMIA VIRUS
PROTEASE


(Equine
infectious
anemia virus)
PF00077
(RVP)
4 ASP A  29
GLY A  55
PRO A  86
ILE A  89
LP1  A 201 (-3.6A)
LP1  A 201 (-3.4A)
LP1  A 201 (-3.9A)
LP1  A 201 (-4.2A)
0.40A 1n49D-2fmbA:
15.2
1n49D-2fmbA:
32.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggv NON-STRUCTURAL
PROTEIN 3


(West Nile virus)
PF00949
(Peptidase_S7)
4 ASP B  75
GLY B 148
ILE B 139
ILE B 123
None
0.93A 1n49D-2ggvB:
undetectable
1n49D-2ggvB:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i4c BICARBONATE
TRANSPORTER


(Synechocystis
sp. PCC 6803)
PF13379
(NMT1_2)
4 GLY A 380
ILE A 377
PRO A 123
ILE A 132
None
0.84A 1n49D-2i4cA:
undetectable
1n49D-2i4cA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ia2 PUTATIVE
TRANSCRIPTIONAL
REGULATOR


(Rhodococcus
jostii)
PF01614
(IclR)
PF09339
(HTH_IclR)
4 ASP A 120
GLY A 140
PRO A  93
ILE A 115
None
0.81A 1n49D-2ia2A:
undetectable
1n49D-2ia2A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jv2 PUTATIVE
UNCHARACTERIZED
PROTEIN PH1500


(Pyrococcus
horikoshii)
PF02933
(CDC48_2)
4 ASP A  46
GLY A  49
ILE A  50
PRO A  21
None
0.91A 1n49D-2jv2A:
undetectable
1n49D-2jv2A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kfk CELL DIVISION
CONTROL PROTEIN 24


(Saccharomyces
cerevisiae)
PF00564
(PB1)
4 ASN B 134
ASP B 127
GLY B 161
ILE B 133
None
0.88A 1n49D-2kfkB:
undetectable
1n49D-2kfkB:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2plc PHOSPHATIDYLINOSITOL
-SPECIFIC
PHOSPHOLIPASE C


(Listeria
monocytogenes)
PF00388
(PI-PLC-X)
4 ASP A 229
GLY A 273
ILE A  41
ILE A 162
None
0.93A 1n49D-2plcA:
undetectable
1n49D-2plcA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pun METHYLTHIORIBOSE
KINASE


(Bacillus
subtilis)
PF01636
(APH)
4 ASP A 250
GLY A  39
ILE A  38
ILE A 122
MG  A 401 ( 2.8A)
ACP  A 999 ( 4.1A)
None
ACP  A 999 (-4.5A)
0.88A 1n49D-2punA:
undetectable
1n49D-2punA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pwz MALATE DEHYDROGENASE

(Escherichia
coli)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ASN A  94
GLY A  10
ILE A  12
ILE A  97
None
0.93A 1n49D-2pwzA:
undetectable
1n49D-2pwzA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvl DIACYLGLYCEROL
KINASE DGKB


(Staphylococcus
aureus)
PF00781
(DAGK_cat)
4 ASP A 290
GLY A  88
ILE A  63
ILE A  78
None
0.77A 1n49D-2qvlA:
undetectable
1n49D-2qvlA:
15.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2rkf PROTEASE RETROPEPSIN

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
4 ASP A  29
GLY A  49
ILE A  50
ILE A  84
AB1  A 501 ( 3.3A)
AB1  A 501 (-3.5A)
AB1  A 501 (-3.8A)
AB1  A 501 ( 4.2A)
0.51A 1n49D-2rkfA:
20.4
1n49D-2rkfA:
83.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2rkf PROTEASE RETROPEPSIN

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
4 ASP A  29
ILE A  50
PRO A  81
ILE A  84
AB1  A 501 ( 3.3A)
AB1  A 501 (-3.8A)
AB1  A 501 (-4.2A)
AB1  A 501 ( 4.2A)
0.46A 1n49D-2rkfA:
20.4
1n49D-2rkfA:
83.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2voy CATION-TRANSPORTING
ATPASE
SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 1


(Archaeoglobus
fulgidus;
Oryctolagus
cuniculus)
PF00122
(E1-E2_ATPase)
PF00702
(Hydrolase)
4 ASP I 647
GLY I 619
ILE I 620
ILE H 332
None
0.85A 1n49D-2voyI:
undetectable
1n49D-2voyI:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w37 ORNITHINE
CARBAMOYLTRANSFERASE
, CATABOLIC


(Lactobacillus
hilgardii)
PF00185
(OTCace)
PF02729
(OTCace_N)
4 ASP A 147
GLY A 181
ILE A 183
ILE A  30
None
0.90A 1n49D-2w37A:
undetectable
1n49D-2w37A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv7 CG10997-PA

(Drosophila
melanogaster)
no annotation 4 ASP A  49
GLY A 110
PRO A  21
ILE A  23
None
0.83A 1n49D-2yv7A:
undetectable
1n49D-2yv7A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9s D-ARABINOSE
ISOMERASE


(Aeribacillus
pallidus)
PF02952
(Fucose_iso_C)
PF07881
(Fucose_iso_N1)
PF07882
(Fucose_iso_N2)
4 ASP A 486
GLY A 386
PRO A 373
ILE A 392
None
0.94A 1n49D-3a9sA:
undetectable
1n49D-3a9sA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3anx SPERMIDINE SYNTHASE

(Thermus
thermophilus)
PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N)
4 ASP A 140
GLY A  85
ILE A  83
ILE A 138
MTA  A 315 (-3.9A)
MTA  A 315 (-3.2A)
None
None
0.94A 1n49D-3anxA:
undetectable
1n49D-3anxA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dgz THIOREDOXIN
REDUCTASE 2


(Mus musculus)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 GLY A 172
ILE A 173
PRO A 159
ILE A 283
None
None
None
NA7  A 501 (-3.5A)
0.81A 1n49D-3dgzA:
undetectable
1n49D-3dgzA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dh9 THIOREDOXIN
REDUCTASE 1


(Drosophila
melanogaster)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 GLY A 174
ILE A 175
PRO A 162
ILE A 285
None
0.82A 1n49D-3dh9A:
undetectable
1n49D-3dh9A:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fd0 PUTATIVE
CYSTATHIONINE
BETA-LYASE INVOLVED
IN ALUMINUM
RESISTANCE


(Listeria
innocua)
PF06838
(Met_gamma_lyase)
4 ASP A 136
GLY A 163
ILE A 164
ILE A 155
None
None
None
EDO  A 424 (-4.2A)
0.89A 1n49D-3fd0A:
undetectable
1n49D-3fd0A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT B


(Sulfolobus
solfataricus)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
4 ASP B 907
GLY B 986
PRO B 912
ILE B 909
None
0.88A 1n49D-3hkzB:
undetectable
1n49D-3hkzB:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3if2 AMINOTRANSFERASE

(Psychrobacter
arcticus)
PF00155
(Aminotran_1_2)
4 GLY A  37
ILE A 392
PRO A 217
ILE A 155
None
0.73A 1n49D-3if2A:
undetectable
1n49D-3if2A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iv3 TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 2


(Streptococcus
mutans)
PF01791
(DeoC)
4 ASP A 157
GLY A 200
ILE A 201
ILE A 113
None
EDO  A 331 ( 3.7A)
None
None
0.72A 1n49D-3iv3A:
undetectable
1n49D-3iv3A:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jwp TRANSCRIPTIONAL
REGULATORY PROTEIN
SIR2 HOMOLOGUE


(Plasmodium
falciparum)
PF02146
(SIR2)
4 ASP A 109
GLY A 125
ILE A 171
ILE A  73
None
0.93A 1n49D-3jwpA:
undetectable
1n49D-3jwpA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k6q PUTATIVE LIGAND
BINDING PROTEIN


(Syntrophomonas
wolfei)
PF12910
(PHD_like)
4 ASP A  89
GLY A  65
ILE A  63
ILE A 133
None
0.87A 1n49D-3k6qA:
undetectable
1n49D-3k6qA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kum DIPEPTIDE EPIMERASE

(Enterococcus
faecalis)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 ASP A 108
GLY A 300
ILE A 301
ILE A 271
None
0.88A 1n49D-3kumA:
undetectable
1n49D-3kumA:
20.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mws HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
4 ASP A  29
GLY A  49
ILE A  50
ILE A  84
None
0.42A 1n49D-3mwsA:
19.6
1n49D-3mwsA:
74.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mws HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
4 ASP A  29
ILE A  50
PRO A  81
ILE A  84
None
0.61A 1n49D-3mwsA:
19.6
1n49D-3mwsA:
74.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o4v MTA/SAH NUCLEOSIDASE

(Escherichia
coli)
PF01048
(PNP_UDP_1)
4 ASN A  73
GLY A  51
ILE A  50
ILE A 178
None
None
4CT  A 233 (-3.7A)
None
0.89A 1n49D-3o4vA:
undetectable
1n49D-3o4vA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3obi FORMYLTETRAHYDROFOLA
TE DEFORMYLASE


(Rhodopseudomonas
palustris)
PF00551
(Formyl_trans_N)
4 ASP A 236
GLY A 219
ILE A 218
ILE A 193
None
0.82A 1n49D-3obiA:
undetectable
1n49D-3obiA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I


(Burkholderia
lata)
PF00117
(GATase)
PF00425
(Chorismate_bind)
4 ASP A 581
GLY A 537
ILE A 538
ILE A 516
None
0.62A 1n49D-3r75A:
undetectable
1n49D-3r75A:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swn U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM5


(Schizosaccharomyces
pombe)
PF01423
(LSM)
4 ASP A  46
GLY A  16
ILE A  15
PRO A  75
None
0.78A 1n49D-3swnA:
undetectable
1n49D-3swnA:
24.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ttp HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
4 ASP A  29
GLY A  49
ILE A  50
ILE A  84
017  A 201 (-3.3A)
017  A 201 (-3.0A)
017  A 201 (-3.3A)
017  A 201 (-4.7A)
0.49A 1n49D-3ttpA:
19.4
1n49D-3ttpA:
77.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ttp HIV-1 PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
4 ASP A  29
GLY A  49
PRO A  81
ILE A  84
017  A 201 (-3.3A)
017  A 201 (-3.0A)
017  A 201 (-4.1A)
017  A 201 (-4.7A)
0.51A 1n49D-3ttpA:
19.4
1n49D-3ttpA:
77.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aef NEOPULLULANASE
(ALPHA-AMYLASE II)


(Pyrococcus
furiosus)
PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16561
(AMPK1_CBM)
4 GLY A 452
ILE A 435
PRO A 201
ILE A 205
None
0.82A 1n49D-4aefA:
undetectable
1n49D-4aefA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bof ARGININE DEIMINASE

(Streptococcus
pyogenes)
PF02274
(Amidinotransf)
4 ASN A 178
ASP A 212
ILE A 252
ILE A 219
None
0.94A 1n49D-4bofA:
undetectable
1n49D-4bofA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bv6 APOPTOSIS-INDUCING
FACTOR 1,
MITOCHONDRIAL


(Homo sapiens)
PF07992
(Pyr_redox_2)
PF14721
(AIF_C)
4 GLY A 575
ILE A 576
PRO A 345
ILE A 343
None
0.72A 1n49D-4bv6A:
undetectable
1n49D-4bv6A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emk U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM5


(Schizosaccharomyces
pombe)
PF01423
(LSM)
4 ASP A  46
GLY A  16
ILE A  15
PRO A  75
None
0.71A 1n49D-4emkA:
undetectable
1n49D-4emkA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eyz CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES


(Ruminococcus
flavefaciens)
no annotation 4 ASP A  49
GLY A 190
ILE A 218
ILE A  38
None
0.92A 1n49D-4eyzA:
undetectable
1n49D-4eyzA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6x THIAZOLINE
OXIDASE/SUBTILISIN-L
IKE PROTEASE


(Prochloron
didemni)
PF00082
(Peptidase_S8)
4 ASN A 645
GLY A 628
PRO A 787
ILE A 546
None
0.91A 1n49D-4h6xA:
undetectable
1n49D-4h6xA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hdj OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMB


(Pseudomonas
aeruginosa)
PF13360
(PQQ_2)
4 ASP A 147
GLY A 160
PRO A 187
ILE A 189
None
0.94A 1n49D-4hdjA:
undetectable
1n49D-4hdjA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ic5 PROTEASE DO-LIKE 5,
CHLOROPLASTIC


(Arabidopsis
thaliana)
PF13365
(Trypsin_2)
4 ASN A 281
GLY A 234
ILE A 233
ILE A 261
None
0.78A 1n49D-4ic5A:
undetectable
1n49D-4ic5A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ixu ARGINASE-2,
MITOCHONDRIAL


(Homo sapiens)
PF00491
(Arginase)
4 ASP A 256
GLY A 276
ILE A 279
ILE A 252
None
0.94A 1n49D-4ixuA:
undetectable
1n49D-4ixuA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc5 TRANSMEMBRANE
PROTEIN 173


(Mus musculus)
PF15009
(TMEM173)
4 GLY A 165
ILE A 164
PRO A 172
ILE A 229
None
0.92A 1n49D-4jc5A:
undetectable
1n49D-4jc5A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l9a PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1393C


(Streptococcus
mutans)
no annotation 4 ASN A 237
GLY A 123
ILE A 122
ILE A 212
None
0.94A 1n49D-4l9aA:
undetectable
1n49D-4l9aA:
14.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4njv PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
5 ASP A  29
GLY A  49
ILE A  50
PRO A  81
ILE A  84
RIT  A 500 (-3.2A)
RIT  A 500 (-3.4A)
RIT  A 500 (-4.3A)
RIT  A 500 (-3.9A)
RIT  A 500 (-4.3A)
0.48A 1n49D-4njvA:
20.2
1n49D-4njvA:
83.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ogz PUTATIVE
ALPHA-GALACTOSIDASE/
MELIBIASE


(Bacteroides
fragilis)
PF10632
(He_PIG_assoc)
PF16499
(Melibiase_2)
PF17450
(Melibiase_2_C)
4 ASN A 131
GLY A 318
ILE A 319
ILE A 355
None
0.83A 1n49D-4ogzA:
undetectable
1n49D-4ogzA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pe5 GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B


(Rattus
norvegicus)
PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)
4 ASP B 306
ILE B  37
PRO B 317
ILE B 314
None
0.91A 1n49D-4pe5B:
undetectable
1n49D-4pe5B:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q3r ARGINASE

(Schistosoma
mansoni)
PF00491
(Arginase)
4 ASP A 267
GLY A 287
ILE A 290
ILE A 263
None
0.90A 1n49D-4q3rA:
undetectable
1n49D-4q3rA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvu UNCHARACTERIZED
PROTEIN


(Bacillus cereus)
PF16285
(DUF4931)
4 ASN A 169
ASP A 159
GLY A 164
ILE A 163
None
0.79A 1n49D-4qvuA:
undetectable
1n49D-4qvuA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3u 2-HYDROXYISOBUTYRYL-
COA MUTASE LARGE
SUBUNIT


(Aquincola
tertiaricarbonis)
PF01642
(MM_CoA_mutase)
4 GLY A 551
ILE A 552
PRO A 214
ILE A 212
None
0.87A 1n49D-4r3uA:
undetectable
1n49D-4r3uA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rsx TYPE III EFFECTOR
HOPA1


(Pseudomonas
syringae group
genomosp. 3)
no annotation 4 ASP A 278
GLY A 265
ILE A 221
ILE A 238
None
0.81A 1n49D-4rsxA:
undetectable
1n49D-4rsxA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w6z ALCOHOL
DEHYDROGENASE 1


(Saccharomyces
cerevisiae)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 ASP A 220
GLY A 199
ILE A 175
ILE A 227
None
0.94A 1n49D-4w6zA:
undetectable
1n49D-4w6zA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5af7 ACYL-COA
DEHYDROGENASE


(Advenella
mimigardefordensis)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
4 ASP A  67
GLY A  51
ILE A  94
ILE A  72
None
0.94A 1n49D-5af7A:
undetectable
1n49D-5af7A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bn4 NEQ263
V-TYPE ATP SYNTHASE
ALPHA CHAIN


(Nanoarchaeum
equitans)
PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF16886
(ATP-synt_ab_Xtn)
4 GLY A  82
ILE A 283
PRO B 101
ILE A  90
None
0.94A 1n49D-5bn4A:
undetectable
1n49D-5bn4A:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d86 PROBABLE SIDEROPHORE
BIOSYNTHESIS PROTEIN
SBNA


(Staphylococcus
aureus)
PF00291
(PALP)
4 ASP A 250
GLY A 257
ILE A 277
ILE A 229
None
0.77A 1n49D-5d86A:
undetectable
1n49D-5d86A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5enz UDP-GLCNAC
2-EPIMERASE


(Staphylococcus
aureus)
PF02350
(Epimerase_2)
4 ASN A 346
GLY A 284
ILE A 285
ILE A 175
None
UDP  A 401 (-3.5A)
None
None
0.78A 1n49D-5enzA:
undetectable
1n49D-5enzA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fva NUCLEOPROTEIN

(Sandfly fever
Naples
phlebovirus)
PF05733
(Tenui_N)
4 ASN A  28
GLY A 157
ILE A 158
PRO A  37
None
0.93A 1n49D-5fvaA:
undetectable
1n49D-5fvaA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikj CRYPTIC LOCI
REGULATOR 2
CRYPTIC LOCI
REGULATOR PROTEIN 1


(Schizosaccharomyces
pombe)
PF10383
(Clr2)
PF16761
(Clr2_transil)
no annotation
4 ASP A 223
GLY A 370
PRO B1221
ILE B1225
None
0.62A 1n49D-5ikjA:
undetectable
1n49D-5ikjA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jr9 NEQ131

(Nanoarchaeum
equitans)
PF01997
(Translin)
4 ASP B 167
GLY B 116
ILE B 115
ILE B 172
None
0.91A 1n49D-5jr9B:
undetectable
1n49D-5jr9B:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA


(Sinorhizobium
meliloti)
PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg)
4 ASP A 221
GLY A 261
ILE A 301
ILE A 201
None
0.88A 1n49D-5kf7A:
undetectable
1n49D-5kf7A:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m8j DIVALENT METAL
CATION TRANSPORTER
MNTH


(Eremococcus
coleocola)
PF01566
(Nramp)
4 ASP A  18
GLY A 166
ILE A 165
ILE A 349
None
0.94A 1n49D-5m8jA:
undetectable
1n49D-5m8jA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mju EXCITATORY AMINO
ACID TRANSPORTER
1,NEUTRAL AMINO ACID
TRANSPORTER
B(0),EXCITATORY
AMINO ACID
TRANSPORTER 1


(Homo sapiens)
PF00375
(SDF)
4 ASP A 174
GLY A 422
ILE A 423
ILE A 433
None
0.74A 1n49D-5mjuA:
undetectable
1n49D-5mjuA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msx PUTATIVE
ENDO-1,4-BETA-XYLANA
SE


(Bacteroides
thetaiotaomicron)
PF00754
(F5_F8_type_C)
PF04616
(Glyco_hydro_43)
4 ASP A 374
GLY A 453
ILE A 454
ILE A 334
None
0.85A 1n49D-5msxA:
undetectable
1n49D-5msxA:
13.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5t2z PROTEASE

(Human
immunodeficiency
virus 1)
PF00077
(RVP)
5 ASP A  29
GLY A  49
ILE A  50
PRO A  81
ILE A  84
None
0.57A 1n49D-5t2zA:
19.5
1n49D-5t2zA:
76.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1o GLUTATHIONE
REDUCTASE


(Vibrio
parahaemolyticus)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
4 GLY A 158
ILE A 159
PRO A 147
ILE A 265
None
0.91A 1n49D-5u1oA:
undetectable
1n49D-5u1oA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsx CHITINASE

(Thermococcus
chitonophagus)
no annotation 4 ASP A 487
GLY A 484
ILE A 483
ILE A 700
GOL  A1004 (-3.5A)
None
None
None
0.79A 1n49D-5xsxA:
undetectable
1n49D-5xsxA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1


(Homo sapiens)
no annotation 4 GLY A1596
ILE A1597
PRO A1626
ILE A1628
None
0.87A 1n49D-6bhcA:
undetectable
1n49D-6bhcA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bq6 THERMOSPERMINE
SYNTHASE


(Medicago
truncatula)
no annotation 4 ASP A 160
GLY A 106
ILE A 104
ILE A 158
None
TER  A 402 ( 4.1A)
None
None
0.94A 1n49D-6bq6A:
undetectable
1n49D-6bq6A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ci9 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE


(Mycolicibacterium
smegmatis)
no annotation 4 ASP A  43
GLY A  18
ILE A  19
ILE A  36
None
NAP  A 301 (-3.2A)
NAP  A 301 (-3.8A)
None
0.94A 1n49D-6ci9A:
undetectable
1n49D-6ci9A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fhw GLUCOAMYLASE P

(Amorphotheca
resinae)
no annotation 4 ASP A 155
GLY A 281
ILE A 283
ILE A 162
None
0.80A 1n49D-6fhwA:
undetectable
1n49D-6fhwA:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6upj HIV-2 PROTEASE

(Human
immunodeficiency
virus 2)
PF00077
(RVP)
4 ASP A  29
GLY A  48
PRO A  81
ILE A  84
None
0.93A 1n49D-6upjA:
18.0
1n49D-6upjA:
47.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7mdh PROTEIN (MALATE
DEHYDROGENASE)


(Sorghum bicolor)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 ASN A 147
GLY A  53
ILE A 129
ILE A 150
None
0.88A 1n49D-7mdhA:
undetectable
1n49D-7mdhA:
15.14