SIMILAR PATTERNS OF AMINO ACIDS FOR 1N49_B_RITB301_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1axn | ANNEXIN III (Homo sapiens) |
PF00191(Annexin) | 4 | ASP A 71ILE A 57ALA A 31ILE A 32 | None | 0.65A | 1n49A-1axnA:undetectable | 1n49A-1axnA:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bo4 | PROTEIN (SERRATIAMARCESCENSAMINOGLYCOSIDE-3-N-ACETYLTRANSFERASE) (Serratiamarcescens) |
PF00583(Acetyltransf_1) | 4 | GLY A 25ILE A 26ALA A 125ILE A 122 | NoneNoneNoneCOA A 300 ( 4.1A) | 0.73A | 1n49A-1bo4A:undetectable | 1n49A-1bo4A:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hcu | ALPHA-1,2-MANNOSIDASE (Trichodermareesei) |
PF01532(Glyco_hydro_47) | 5 | ASP A 114GLY A 108ILE A 59ALA A 65ILE A 66 | None | 0.92A | 1n49A-1hcuA:undetectable | 1n49A-1hcuA:12.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 29GLY A 49ILE A 50PRO A 81ILE A 84 | A79 A 800 (-2.7A)A79 A 800 (-3.4A)A79 A 800 ( 4.0A)A79 A 800 ( 3.4A)A79 A 800 (-3.8A) | 0.37A | 1n49A-1hvcA:14.0 | 1n49A-1hvcA:47.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 29GLY A 49ILE A 50PRO A 81ILE A 84 | A79 A 800 (-2.8A)A79 A 800 ( 3.7A)A79 A 800 (-3.8A)A79 A 800 ( 3.9A)A79 A 800 (-3.6A) | 0.61A | 1n49A-1hvcA:14.0 | 1n49A-1hvcA:47.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqk | CARBON MONOXIDEDEHYDROGENASE (Rhodospirillumrubrum) |
PF03063(Prismane) | 4 | GLY A 513ILE A 512PRO A 243ILE A 409 | None | 0.78A | 1n49A-1jqkA:undetectable | 1n49A-1jqkA:10.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n5x | XANTHINEDEHYDROGENASE (Bos taurus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 4 | ASP A 638GLY A 668ILE A 666ALA A 813 | None | 0.55A | 1n49A-1n5xA:undetectable | 1n49A-1n5xA:6.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q50 | GLUCOSE-6-PHOSPHATEISOMERASE (Leishmaniamexicana) |
PF00342(PGI) | 4 | ASN A 381GLY A 556ILE A 557ILE A 377 | None | 0.66A | 1n49A-1q50A:undetectable | 1n49A-1q50A:10.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sb8 | WBPP (Pseudomonasaeruginosa) |
PF01370(Epimerase) | 4 | ASP A 235ILE A 239PRO A 212ALA A 209 | NoneNoneNoneUD2 A 343 (-3.6A) | 0.76A | 1n49A-1sb8A:undetectable | 1n49A-1sb8A:15.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1siv | SIV PROTEASE (Simianimmunodeficiencyvirus) |
PF00077(RVP) | 5 | ASP A 29GLY A 49ILE A 50PRO A 81ILE A 84 | None | 0.36A | 1n49A-1sivA:18.6 | 1n49A-1sivA:48.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tkk | SIMILAR TOCHLOROMUCONATECYCLOISOMERASE (Bacillussubtilis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASP A 109GLY A 303ALA A 278ILE A 275 | None | 0.63A | 1n49A-1tkkA:undetectable | 1n49A-1tkkA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tkk | SIMILAR TOCHLOROMUCONATECYCLOISOMERASE (Bacillussubtilis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASP A 109GLY A 303ILE A 304ILE A 275 | None | 0.76A | 1n49A-1tkkA:undetectable | 1n49A-1tkkA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ttu | LIN-12 AND GLP-1TRANSCRIPTIONALREGULATOR (Caenorhabditiselegans) |
PF01833(TIG)PF09270(BTD)PF09271(LAG1-DNAbind) | 4 | GLY A 291ILE A 292PRO A 240ILE A 219 | None | 0.75A | 1n49A-1ttuA:undetectable | 1n49A-1ttuA:12.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ua2 | CELL DIVISIONPROTEIN KINASE 7 (Homo sapiens) |
PF00069(Pkinase) | 4 | ASP A 79GLY A 82ALA A 59ILE A 63 | None | 0.77A | 1n49A-1ua2A:undetectable | 1n49A-1ua2A:15.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ued | P450 MONOOXYGENASE (Amycolatopsisorientalis) |
PF00067(p450) | 4 | ASP A 327ILE A 67PRO A 295ALA A 294 | NoneNoneHEM A1430 (-4.6A)None | 0.68A | 1n49A-1uedA:undetectable | 1n49A-1uedA:14.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1woq | INORGANICPOLYPHOSPHATE/ATP-GLUCOMANNOKINASE (Arthrobactersp. KM) |
PF00480(ROK) | 4 | ASN A 122GLY A 152ILE A 153ALA A 127 | BGC A 290 (-3.2A)BGC A 290 ( 3.7A)NoneNone | 0.72A | 1n49A-1woqA:undetectable | 1n49A-1woqA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wue | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Enterococcusfaecalis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASP A1110GLY A1298ALA A1273ILE A1270 | None | 0.77A | 1n49A-1wueA:undetectable | 1n49A-1wueA:15.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bx7 | DIHYDROOROTATEDEHYDROGENASE (Lactococcuslactis) |
PF01180(DHO_dh) | 4 | GLY A 271ILE A 270ALA A 228ILE A 224 | FMN A1312 (-3.4A)NoneNoneFMN A1312 ( 4.9A) | 0.78A | 1n49A-2bx7A:undetectable | 1n49A-2bx7A:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bzn | GMP REDUCTASE 2 (Homo sapiens) |
PF00478(IMPDH) | 4 | ASP A 237ILE A 154ALA A 75ILE A 51 | None | 0.69A | 1n49A-2bznA:undetectable | 1n49A-2bznA:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ch1 | 3-HYDROXYKYNURENINETRANSAMINASE (Anophelesgambiae) |
PF00266(Aminotran_5) | 4 | ASP A 127GLY A 102ILE A 103ALA A 182 | NoneNoneNonePLP A1390 (-3.5A) | 0.79A | 1n49A-2ch1A:undetectable | 1n49A-2ch1A:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ckh | SENTRIN-SPECIFICPROTEASE 1 (Homo sapiens) |
PF02902(Peptidase_C48) | 4 | GLY A 554ILE A 555ALA A 537ILE A 528 | None | 0.68A | 1n49A-2ckhA:undetectable | 1n49A-2ckhA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2czc | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Pyrococcushorikoshii) |
PF01113(DapB_N)PF02800(Gp_dh_C) | 4 | ASN A 306ASP A 85GLY A 11ALA A 20 | NoneNoneNAD A 501 (-3.3A)None | 0.77A | 1n49A-2czcA:undetectable | 1n49A-2czcA:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d16 | HYPOTHETICAL PROTEINPH1918 (Pyrococcushorikoshii) |
PF04008(Adenosine_kin) | 4 | ASP A 8ILE A 4ALA A 79ILE A 77 | None | 0.72A | 1n49A-2d16A:undetectable | 1n49A-2d16A:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e0p | ENDOGLUCANASE (Ruminiclostridiumthermocellum) |
PF12891(Glyco_hydro_44) | 4 | ASP A 300GLY A 364PRO A 286ALA A 288 | None | 0.79A | 1n49A-2e0pA:undetectable | 1n49A-2e0pA:12.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ec5 | DERMONECROTIC TOXIN (Pasteurellamultocida) |
PF11647(MLD) | 4 | ASP A 739GLY A 803ILE A 802ILE A 734 | None | 0.73A | 1n49A-2ec5A:undetectable | 1n49A-2ec5A:9.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eij | CYTOCHROME C OXIDASESUBUNIT 1 (Bos taurus) |
PF00115(COX1) | 4 | GLY A 250ILE A 254ALA A 276ILE A 280 | None | 0.62A | 1n49A-2eijA:undetectable | 1n49A-2eijA:11.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f4e | ATFKBP42 (Arabidopsisthaliana) |
PF00254(FKBP_C) | 4 | ASP A 148GLY A 108ILE A 111ALA A 122 | None | 0.70A | 1n49A-2f4eA:undetectable | 1n49A-2f4eA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f5x | BUGD (Bordetellapertussis) |
PF03401(TctC) | 4 | ASN A 132GLY A 45PRO A 164ALA A 165 | None | 0.79A | 1n49A-2f5xA:undetectable | 1n49A-2f5xA:16.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fmb | EQUINE INFECTIOUSANEMIA VIRUSPROTEASE (Equineinfectiousanemia virus) |
PF00077(RVP) | 4 | ASP A 29GLY A 55PRO A 86ILE A 89 | LP1 A 201 (-3.6A)LP1 A 201 (-3.4A)LP1 A 201 (-3.9A)LP1 A 201 (-4.2A) | 0.39A | 1n49A-2fmbA:15.2 | 1n49A-2fmbA:32.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2if4 | ATFKBP42 (Arabidopsisthaliana) |
PF00254(FKBP_C)PF13181(TPR_8) | 4 | ASP A 148GLY A 108ILE A 111ALA A 122 | None | 0.58A | 1n49A-2if4A:undetectable | 1n49A-2if4A:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jbw | 2,6-DIHYDROXY-PSEUDO-OXYNICOTINEHYDROLASE (Paenarthrobacternicotinovorans) |
PF06500(DUF1100) | 4 | ASN A 50ASP A 43GLY A 94ALA A 75 | None | 0.75A | 1n49A-2jbwA:undetectable | 1n49A-2jbwA:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qpt | EH DOMAIN-CONTAININGPROTEIN-2 (Mus musculus) |
PF00350(Dynamin_N)PF12763(EF-hand_4)PF16880(EHD_N) | 4 | ASP A 198GLY A 205ALA A 64ILE A 157 | None | 0.75A | 1n49A-2qptA:undetectable | 1n49A-2qptA:10.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qvl | DIACYLGLYCEROLKINASE DGKB (Staphylococcusaureus) |
PF00781(DAGK_cat) | 4 | ASP A 290GLY A 88ILE A 63ILE A 78 | None | 0.77A | 1n49A-2qvlA:undetectable | 1n49A-2qvlA:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r44 | UNCHARACTERIZEDPROTEIN (Cytophagahutchinsonii) |
PF07726(AAA_3) | 5 | ASP A 147GLY A 105ILE A 88ALA A 114ILE A 112 | None | 1.28A | 1n49A-2r44A:undetectable | 1n49A-2r44A:16.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rkf | PROTEASE RETROPEPSIN (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 6 | ASP A 29GLY A 49ILE A 50PRO A 81ALA A 82ILE A 84 | AB1 A 501 ( 3.3A)AB1 A 501 (-3.5A)AB1 A 501 (-3.8A)AB1 A 501 (-4.2A)AB1 A 501 (-3.6A)AB1 A 501 ( 4.2A) | 0.44A | 1n49A-2rkfA:20.5 | 1n49A-2rkfA:83.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rkf | PROTEASE RETROPEPSIN (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | GLY A 48PRO A 81ALA A 82ILE A 84 | AB1 A 501 (-4.2A)AB1 A 501 (-4.2A)AB1 A 501 (-3.6A)AB1 A 501 ( 4.2A) | 0.76A | 1n49A-2rkfA:20.5 | 1n49A-2rkfA:83.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vvr | RIBOSE-5-PHOSPHATEISOMERASE B (Escherichiacoli) |
PF02502(LacAB_rpiB) | 4 | ASP A 42GLY A 71ILE A 74ALA A 51 | None | 0.63A | 1n49A-2vvrA:undetectable | 1n49A-2vvrA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w48 | SORBITOL OPERONREGULATOR (Klebsiellapneumoniae) |
PF04198(Sugar-bind)PF13936(HTH_38) | 4 | GLY A 293ILE A 251PRO A 215ALA A 216 | None | 0.72A | 1n49A-2w48A:undetectable | 1n49A-2w48A:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnw | ACTIVATED BYTRANSCRIPTION FACTORSSRB (Salmonellaenterica) |
PF02055(Glyco_hydro_30)PF17189(Glyco_hydro_30C) | 4 | GLY A 327ILE A 45ALA A 282ILE A 278 | None | 0.63A | 1n49A-2wnwA:undetectable | 1n49A-2wnwA:12.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xzo | REGULATOR OFNONSENSE TRANSCRIPTS1 (Homo sapiens) |
PF04851(ResIII)PF13086(AAA_11)PF13087(AAA_12) | 4 | GLY A 791ILE A 792ALA A 828ILE A 525 | NoneNone U D 4 ( 3.8A)None | 0.75A | 1n49A-2xzoA:undetectable | 1n49A-2xzoA:10.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yp6 | THIOREDOXIN FAMILYPROTEIN (Streptococcuspneumoniae) |
PF00578(AhpC-TSA) | 4 | ILE A 149PRO A 50ALA A 49ILE A 164 | None | 0.78A | 1n49A-2yp6A:undetectable | 1n49A-2yp6A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yyy | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Methanocaldococcusjannaschii) |
PF01113(DapB_N)PF02800(Gp_dh_C) | 4 | ASN A 315ASP A 87GLY A 11ALA A 20 | NoneNoneNAP A2001 (-3.2A)None | 0.77A | 1n49A-2yyyA:undetectable | 1n49A-2yyyA:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aqp | PROBABLE SECDFPROTEIN-EXPORTMEMBRANE PROTEIN (Thermusthermophilus) |
PF02355(SecD_SecF)PF07549(Sec_GG) | 4 | GLY A 429ILE A 431ALA A 362ILE A 363 | None | 0.75A | 1n49A-3aqpA:undetectable | 1n49A-3aqpA:9.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bf0 | PROTEASE 4 (Escherichiacoli) |
PF01343(Peptidase_S49) | 4 | GLY A 411PRO A 417ALA A 418ILE A 421 | None | 0.73A | 1n49A-3bf0A:undetectable | 1n49A-3bf0A:11.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckb | SUSD (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB) | 4 | GLY A 458ILE A 460ALA A 250ILE A 254 | None | 0.71A | 1n49A-3ckbA:undetectable | 1n49A-3ckbA:11.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dfh | MANDELATE RACEMASE (VibrionalesbacteriumSWAT-3) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASN A 322GLY A 94PRO A 291ALA A 292 | None | 0.75A | 1n49A-3dfhA:undetectable | 1n49A-3dfhA:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dfh | MANDELATE RACEMASE (VibrionalesbacteriumSWAT-3) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASP A 101GLY A 318ALA A 292ILE A 289 | None | 0.75A | 1n49A-3dfhA:undetectable | 1n49A-3dfhA:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewd | ADENOSINE DEAMINASE (Plasmodiumvivax) |
PF00962(A_deaminase) | 5 | ASP A 184GLY A 171ILE A 170ALA A 134ILE A 141 | None | 1.26A | 1n49A-3ewdA:undetectable | 1n49A-3ewdA:14.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hee | RIBOSE-5-PHOSPHATEISOMERASE (Ruminiclostridiumthermocellum) |
PF02502(LacAB_rpiB) | 4 | ASP A 41GLY A 70ILE A 73ALA A 50 | NoneR5P A 651 (-3.3A)NoneNone | 0.65A | 1n49A-3heeA:undetectable | 1n49A-3heeA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3igh | UNCHARACTERIZEDMETAL-DEPENDENTHYDROLASE (Pyrococcushorikoshii) |
PF07969(Amidohydro_3) | 4 | GLY X 121ILE X 147ALA X 188ILE X 192 | None | 0.79A | 1n49A-3ighX:undetectable | 1n49A-3ighX:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k8c | RIBOSE 5-PHOSPHATEISOMERASE (Trypanosomacruzi) |
PF02502(LacAB_rpiB) | 4 | ASP A 45GLY A 74ILE A 77ALA A 54 | NoneRES A 160 (-3.4A)NoneNone | 0.72A | 1n49A-3k8cA:undetectable | 1n49A-3k8cA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kum | DIPEPTIDE EPIMERASE (Enterococcusfaecalis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASP A 108GLY A 300ALA A 274ILE A 271 | None | 0.66A | 1n49A-3kumA:undetectable | 1n49A-3kumA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1p | RIBOSE 5-PHOSPHATEISOMERASE (Trypanosomacruzi) |
PF02502(LacAB_rpiB) | 4 | ASP A 45GLY A 74ILE A 77ALA A 54 | None | 0.74A | 1n49A-3m1pA:undetectable | 1n49A-3m1pA:19.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mws | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 29GLY A 49ILE A 50PRO A 81ILE A 84 | None | 0.46A | 1n49A-3mwsA:19.7 | 1n49A-3mwsA:74.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfe | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Legionellapneumophila) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | GLY A 211ILE A 372ALA A 357ILE A 245 | None | 0.79A | 1n49A-3pfeA:undetectable | 1n49A-3pfeA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ph3 | RIBOSE-5-PHOSPHATEISOMERASE (Ruminiclostridiumthermocellum) |
PF02502(LacAB_rpiB) | 4 | ASP A 41GLY A 70ILE A 73ALA A 50 | NoneRB5 A 150 (-3.5A)NoneNone | 0.67A | 1n49A-3ph3A:undetectable | 1n49A-3ph3A:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4d | POSSIBLECHLOROMUCONATECYCLOISOMERASEMANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY (Cytophagahutchinsonii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASP A 108GLY A 300ALA A 275ILE A 272 | None | 0.72A | 1n49A-3q4dA:undetectable | 1n49A-3q4dA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qtg | PYRUVATE KINASE (Pyrobaculumaerophilum) |
PF00224(PK)PF02887(PK_C) | 4 | ASP A 43ILE A 284ALA A 201ILE A 78 | None | 0.70A | 1n49A-3qtgA:undetectable | 1n49A-3qtgA:11.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r11 | ENZYME OF ENOLASESUPERFAMILY (Francisellaphilomiragia) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASP A 111GLY A 304ALA A 279ILE A 276 | None | 0.76A | 1n49A-3r11A:undetectable | 1n49A-3r11A:15.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r75 | ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI (Burkholderialata) |
PF00117(GATase)PF00425(Chorismate_bind) | 4 | ASP A 581GLY A 537ILE A 538ILE A 516 | None | 0.59A | 1n49A-3r75A:undetectable | 1n49A-3r75A:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sr6 | XANTHINEDEHYDROGENASE/OXIDASE (Bos taurus) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 4 | ASP C 638GLY C 668ILE C 666ALA C 813 | None | 0.74A | 1n49A-3sr6C:undetectable | 1n49A-3sr6C:10.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3t3c | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 29GLY A 49ILE A 50ALA A 82 | 017 A 201 (-3.5A)017 A 201 (-4.0A)017 A 201 (-3.3A)SO4 A 101 (-3.5A) | 0.57A | 1n49A-3t3cA:18.4 | 1n49A-3t3cA:76.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3t3c | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 4 | ASP A 29GLY A 49PRO A 81ALA A 82 | 017 A 201 (-3.5A)017 A 201 (-4.0A)NoneSO4 A 101 (-3.5A) | 0.70A | 1n49A-3t3cA:18.4 | 1n49A-3t3cA:76.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqd | 3-DEOXY-MANNO-OCTULOSONATECYTIDYLYLTRANSFERASE (Coxiellaburnetii) |
PF02348(CTP_transf_3) | 4 | ASP A 100ILE A 6ALA A 58ILE A 30 | None | 0.76A | 1n49A-3tqdA:undetectable | 1n49A-3tqdA:17.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ttp | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 29GLY A 49ILE A 50PRO A 81ILE A 84 | 017 A 201 (-3.3A)017 A 201 (-3.0A)017 A 201 (-3.3A)017 A 201 (-4.1A)017 A 201 (-4.7A) | 0.51A | 1n49A-3ttpA:19.3 | 1n49A-3ttpA:77.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aef | NEOPULLULANASE(ALPHA-AMYLASE II) (Pyrococcusfuriosus) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16561(AMPK1_CBM) | 4 | GLY A 452ILE A 435PRO A 201ILE A 205 | None | 0.78A | 1n49A-4aefA:undetectable | 1n49A-4aefA:10.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d2i | HERA (Sulfolobussolfataricus) |
PF01935(DUF87)PF05872(DUF853)PF09378(HAS-barrel) | 4 | GLY A 449ILE A 451ALA A 445ILE A 410 | None | 0.78A | 1n49A-4d2iA:undetectable | 1n49A-4d2iA:11.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6u | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Acinetobacterbaumannii) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 4 | ASP A 22ILE A 61ALA A 11ILE A 7 | None | 0.79A | 1n49A-4e6uA:undetectable | 1n49A-4e6uA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gis | ENOLASE (Vibrio harveyi) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASN A 320GLY A 92PRO A 289ALA A 290 | None | 0.79A | 1n49A-4gisA:undetectable | 1n49A-4gisA:12.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gtn | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Acinetobactersp. ADP1) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 4 | GLY A 59ILE A 58ALA A 26ILE A 30 | None | 0.60A | 1n49A-4gtnA:undetectable | 1n49A-4gtnA:13.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hdj | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMB (Pseudomonasaeruginosa) |
PF13360(PQQ_2) | 4 | ASP A 147GLY A 160PRO A 187ILE A 189 | None | 0.79A | 1n49A-4hdjA:undetectable | 1n49A-4hdjA:14.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hdj | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMB (Pseudomonasaeruginosa) |
PF13360(PQQ_2) | 4 | GLY A 160ILE A 159PRO A 187ALA A 196 | None | 0.78A | 1n49A-4hdjA:undetectable | 1n49A-4hdjA:14.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ihc | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Dickeyaparadisiaca) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLY A 62ILE A 61ALA A 75ILE A 71 | None | 0.75A | 1n49A-4ihcA:undetectable | 1n49A-4ihcA:10.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jgb | PUTATIVE EXPORTEDPROTEIN (Burkholderiapseudomallei) |
PF13460(NAD_binding_10) | 4 | GLY A 14PRO A 158ALA A 157ILE A 156 | None | 0.77A | 1n49A-4jgbA:undetectable | 1n49A-4jgbA:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kkm | POLYPRENYLSYNTHETASE (Zymomonasmobilis) |
PF00348(polyprenyl_synt) | 4 | GLY A 196ILE A 198ALA A 74ILE A 75 | None | 0.78A | 1n49A-4kkmA:undetectable | 1n49A-4kkmA:19.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4njv | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 29GLY A 49ILE A 50PRO A 81ILE A 84 | RIT A 500 (-3.2A)RIT A 500 (-3.4A)RIT A 500 (-4.3A)RIT A 500 (-3.9A)RIT A 500 (-4.3A) | 0.45A | 1n49A-4njvA:20.3 | 1n49A-4njvA:83.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p52 | HOMOSERINE KINASE (Cytophagahutchinsonii) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | GLY A 106ILE A 110ALA A 60ILE A 46 | None | 0.74A | 1n49A-4p52A:undetectable | 1n49A-4p52A:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qnl | TAIL FIBER PROTEIN (Escherichiavirus G7C) |
no annotation | 4 | ASN A 340GLY A 483ALA A 378ILE A 272 | None | 0.75A | 1n49A-4qnlA:undetectable | 1n49A-4qnlA:8.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3u | 2-HYDROXYISOBUTYRYL-COA MUTASE LARGESUBUNIT (Aquincolatertiaricarbonis) |
PF01642(MM_CoA_mutase) | 4 | GLY A 551ILE A 552PRO A 214ILE A 212 | None | 0.77A | 1n49A-4r3uA:undetectable | 1n49A-4r3uA:9.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z0n | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Streptobacillusmoniliformis) |
PF13407(Peripla_BP_4) | 4 | ASP A 325GLY A 321ALA A 265ILE A 269 | None | 0.77A | 1n49A-4z0nA:undetectable | 1n49A-4z0nA:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z9d | PERTUSSIS TOXIN-LIKESUBUNIT ARTA (Escherichiacoli) |
PF02917(Pertussis_S1) | 5 | ASN A 85GLY A 127ILE A 130ALA A 121ILE A 87 | None | 1.11A | 1n49A-4z9dA:undetectable | 1n49A-4z9dA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zgq | EUKARYOTICTRANSLATIONINITIATION FACTOR 2SUBUNIT GAMMA (Saccharomycescerevisiae) |
PF09173(eIF2_C) | 4 | GLY B 513ILE B 512ALA B 483ILE B 432 | None | 0.71A | 1n49A-4zgqB:undetectable | 1n49A-4zgqB:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bqn | BOTULINUM NEUROTOXINTYPE D,BOTULINUMNEUROTOXIN TYPE D (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07952(Toxin_trans) | 4 | ASP A 397GLY A 405PRO A 419ALA A 420 | None | 0.76A | 1n49A-5bqnA:undetectable | 1n49A-5bqnA:8.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cyu | CONSERVED MEMBRANEPROTEIN (Mycolicibacteriumsmegmatis) |
PF05108(T7SS_ESX1_EccB) | 4 | GLY A 421ILE A 422PRO A 137ILE A 133 | None | 0.75A | 1n49A-5cyuA:undetectable | 1n49A-5cyuA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6n | ACYL-COA SYNTHASE (Mycolicibacteriumsmegmatis) |
PF00501(AMP-binding) | 4 | ASP A 303GLY A 330ALA A 289ILE A 264 | None | 0.64A | 1n49A-5d6nA:undetectable | 1n49A-5d6nA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dmh | UNCHARACTERIZEDPROTEIN CONSERVED INBACTERIA (Cupriavidusnecator) |
PF07005(DUF1537)PF17042(DUF1357_C) | 4 | GLY A 233ILE A 236ALA A 110ILE A 106 | None | 0.64A | 1n49A-5dmhA:undetectable | 1n49A-5dmhA:13.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey8 | ACYL-COA SYNTHASE (Mycolicibacteriumsmegmatis) |
PF00501(AMP-binding) | 4 | ASP A 303GLY A 330ALA A 289ILE A 264 | None | 0.74A | 1n49A-5ey8A:undetectable | 1n49A-5ey8A:11.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fp2 | FERRIC ENTEROBACTINRECEPTOR PIRA (Pseudomonasaeruginosa) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | ASN A 373GLY A 145ALA A 412ILE A 410 | None | 0.73A | 1n49A-5fp2A:undetectable | 1n49A-5fp2A:10.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h9f | CRISPR SYSTEMCASCADE SUBUNIT CASE (Escherichiacoli) |
PF08798(CRISPR_assoc) | 4 | ILE K 123PRO K 92ALA K 90ILE K 183 | None | 0.75A | 1n49A-5h9fK:undetectable | 1n49A-5h9fK:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2t | PERIODIC TRYPTOPHANPROTEIN 2 (Saccharomycescerevisiae) |
PF00400(WD40) | 4 | GLY A 116ILE A 149ALA A 60ILE A 73 | None | 0.78A | 1n49A-5i2tA:undetectable | 1n49A-5i2tA:8.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikj | CRYPTIC LOCIREGULATOR 2CRYPTIC LOCIREGULATOR PROTEIN 1 (Schizosaccharomycespombe) |
PF10383(Clr2)PF16761(Clr2_transil)no annotation | 4 | ASP A 223GLY A 370PRO B1221ILE B1225 | None | 0.65A | 1n49A-5ikjA:undetectable | 1n49A-5ikjA:10.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j32 | 3-ISOPROPYLMALATEDEHYDROGENASE 2,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00180(Iso_dh) | 4 | GLY A 302ILE A 301ALA A 113ILE A 53 | None | 0.76A | 1n49A-5j32A:undetectable | 1n49A-5j32A:14.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l7v | GLYCOSIDE HYDROLASE (Bacteroidesvulgatus) |
PF13320(DUF4091) | 4 | ASP A 379ILE A 355ALA A 359ILE A 358 | None | 0.77A | 1n49A-5l7vA:undetectable | 1n49A-5l7vA:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mju | EXCITATORY AMINOACID TRANSPORTER1,NEUTRAL AMINO ACIDTRANSPORTERB(0),EXCITATORYAMINO ACIDTRANSPORTER 1 (Homo sapiens) |
PF00375(SDF) | 4 | ASP A 174GLY A 422ILE A 423ILE A 433 | None | 0.70A | 1n49A-5mjuA:undetectable | 1n49A-5mjuA:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sv0 | BIOPOLYMER TRANSPORTPROTEIN EXBB (Escherichiacoli) |
no annotation | 4 | GLY B 158ILE B 157ALA B 177ILE B 174 | None | 0.75A | 1n49A-5sv0B:undetectable | 1n49A-5sv0B:17.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5t2z | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | ASP A 29GLY A 49ILE A 50PRO A 81ILE A 84 | None | 0.47A | 1n49A-5t2zA:19.4 | 1n49A-5t2zA:76.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wue | UNCHARACTERIZEDPROTEIN (Sulfolobusacidocaldarius) |
PF03458(UPF0126) | 4 | GLY A 50ILE A 51ALA A 21ILE A 17 | None | 0.77A | 1n49A-5wueA:undetectable | 1n49A-5wueA:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsx | CHITINASE (Thermococcuschitonophagus) |
no annotation | 4 | ASP A 487GLY A 484ILE A 483ILE A 700 | GOL A1004 (-3.5A)NoneNoneNone | 0.78A | 1n49A-5xsxA:undetectable | 1n49A-5xsxA:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aoo | MALATE DEHYDROGENASE (Haemophilusinfluenzae) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | ASP A 150GLY A 145ILE A 116ALA A 235 | None | 0.75A | 1n49A-6aooA:undetectable | 1n49A-6aooA:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bz0 | DIHYDROLIPOYLDEHYDROGENASE (Acinetobacterbaumannii) |
no annotation | 4 | ASP A 425GLY A 420ILE A 419ALA A 460 | None | 0.79A | 1n49A-6bz0A:undetectable | 1n49A-6bz0A:22.64 |