SIMILAR PATTERNS OF AMINO ACIDS FOR 1MZ9_D_VDYD1001_4

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a6j NITROGEN REGULATORY
IIA PROTEIN

(Escherichia
coli) 		PF00359
(PTS_EIIA_2) 		4 THR A 154
LEU A  10
VAL A 127
LEU A 124
 None
 0.90A 1mz9D-1a6jA:
undetectable		 1mz9D-1a6jA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1at3 HERPES SIMPLEX VIRUS
TYPE II PROTEASE

(Human
alphaherpesvirus
2) 		PF00716
(Peptidase_S21) 		4 THR A 210
LEU A 213
VAL A  59
LEU A 151
 None
 0.99A 1mz9D-1at3A:
undetectable		 1mz9D-1at3A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1awc PROTEIN (GA BINDING
PROTEIN BETA 1)

(Mus musculus) 		PF12796
(Ank_2)
PF13637
(Ank_4) 		4 THR B  54
LEU B  57
VAL B  22
LEU B  25
 None
 0.92A 1mz9D-1awcB:
undetectable		 1mz9D-1awcB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aye PROCARBOXYPEPTIDASE
A2

(Homo sapiens) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		4 THR A  54
LEU A  32
VAL A  33
LEU A  25
 None
 0.86A 1mz9D-1ayeA:
undetectable		 1mz9D-1ayeA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dtd CARBOXYPEPTIDASE A2

(Homo sapiens) 		PF00246
(Peptidase_M14) 		4 THR A 410
LEU A 388
VAL A 389
LEU A 381
 None
 0.87A 1mz9D-1dtdA:
undetectable		 1mz9D-1dtdA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fba FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE

(Drosophila
melanogaster) 		PF00274
(Glycolytic) 		4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.60A 1mz9D-1fbaA:
undetectable		 1mz9D-1fbaA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fdj FRUCTOSE
1,6-BISPHOSPHATE
ALDOLASE

(Oryctolagus
cuniculus) 		PF00274
(Glycolytic) 		4 THR A1205
LEU A1209
VAL A1212
LEU A1216
 None
 0.64A 1mz9D-1fdjA:
undetectable		 1mz9D-1fdjA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h0h FORMATE
DEHYDROGENASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 THR A 623
LEU A 619
VAL A 616
LEU A 612
 None
 0.99A 1mz9D-1h0hA:
undetectable		 1mz9D-1h0hA:
3.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6g TIP120 PROTEIN

(Homo sapiens) 		PF08623
(TIP120) 		4 THR C 611
LEU C 612
VAL C 647
LEU C 648
 None
 0.85A 1mz9D-1u6gC:
undetectable		 1mz9D-1u6gC:
3.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w55 ISPD/ISPF
BIFUNCTIONAL ENZYME

(Campylobacter
jejuni) 		PF01128
(IspD)
PF02542
(YgbB) 		4 THR A  38
LEU A  41
VAL A 102
LEU A 106
 None
 0.82A 1mz9D-1w55A:
undetectable		 1mz9D-1w55A:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wek HYPOTHETICAL PROTEIN
TT1465

(Thermus
thermophilus) 		PF03641
(Lysine_decarbox) 		4 THR A 144
LEU A 148
VAL A 151
LEU A 155
 PO4  A 501 (-3.9A)
None
None
None
 0.99A 1mz9D-1wekA:
undetectable		 1mz9D-1wekA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfb ALDOLASE C

(Homo sapiens) 		PF00274
(Glycolytic) 		4 THR A 206
LEU A 210
VAL A 213
LEU A 217
 None
 0.62A 1mz9D-1xfbA:
undetectable		 1mz9D-1xfbA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y3t HYPOTHETICAL PROTEIN
YXAG

(Bacillus
subtilis) 		PF07883
(Cupin_2) 		4 THR A  34
LEU A  50
VAL A 115
LEU A  72
 None
 0.98A 1mz9D-1y3tA:
undetectable		 1mz9D-1y3tA:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y9u PUTATIVE IRON
BINDING PROTEIN

(Bordetella
pertussis) 		PF13343
(SBP_bac_6) 		4 THR A 160
LEU A 164
VAL A 167
LEU A 171
 None
 0.86A 1mz9D-1y9uA:
undetectable		 1mz9D-1y9uA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF01467
(CTP_transf_like) 		4 THR A  85
LEU A  89
VAL A  92
LEU A  96
 None
 0.85A 1mz9D-1yulA:
undetectable		 1mz9D-1yulA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9s COMPETENCE/DAMAGE-IN
DUCIBLE PROTEIN CINA

(Agrobacterium
fabrum) 		PF02464
(CinA) 		4 THR A 146
LEU A 150
VAL A 153
LEU A 157
 None
 0.78A 1mz9D-2a9sA:
undetectable		 1mz9D-2a9sA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bl2 V-TYPE SODIUM ATP
SYNTHASE SUBUNIT K

(Enterococcus
hirae) 		PF00137
(ATP-synt_C) 		4 THR A 140
LEU A 144
VAL A 147
LEU A 151
 None
 0.79A 1mz9D-2bl2A:
undetectable		 1mz9D-2bl2A:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ekf ANCIENT UBIQUITOUS
PROTEIN 1

(Homo sapiens) 		PF02845
(CUE) 		4 THR A  15
LEU A  16
VAL A  42
LEU A  44
 None
 0.67A 1mz9D-2ekfA:
undetectable		 1mz9D-2ekfA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2huj LIN2004 PROTEIN

(Listeria
innocua) 		PF08807
(DUF1798) 		4 THR A 103
LEU A 107
VAL A 110
LEU A 114
 None
 0.85A 1mz9D-2hujA:
undetectable		 1mz9D-2hujA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l3t TRANSCRIPTION
ELONGATION FACTOR
SPT6

(Saccharomyces
cerevisiae) 		PF14633
(SH2_2) 		4 THR A 102
LEU A  98
VAL A  95
LEU A  91
 None
 0.81A 1mz9D-2l3tA:
undetectable		 1mz9D-2l3tA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nps SYNTAXIN-6

(Homo sapiens) 		no annotation 4 THR D 211
LEU D 215
VAL D 218
LEU D 222
 None
 0.65A 1mz9D-2npsD:
4.1		 1mz9D-2npsD:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okj GLUTAMATE
DECARBOXYLASE 1

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 THR A 113
LEU A 117
VAL A 120
LEU A 124
 None
 0.81A 1mz9D-2okjA:
undetectable		 1mz9D-2okjA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okk GLUTAMATE
DECARBOXYLASE 2

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		4 THR A 107
LEU A 111
VAL A 114
LEU A 118
 None
 0.87A 1mz9D-2okkA:
undetectable		 1mz9D-2okkA:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pl3 PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX10

(Homo sapiens) 		PF00270
(DEAD) 		4 THR A 120
LEU A 124
VAL A 127
LEU A 131
 ADP  A 300 (-3.6A)
None
None
None
 0.79A 1mz9D-2pl3A:
undetectable		 1mz9D-2pl3A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q0q ARYL ESTERASE

(Mycolicibacterium
smegmatis) 		PF13472
(Lipase_GDSL_2) 		4 THR A 161
LEU A 164
VAL A 167
LEU A 171
 None
 0.97A 1mz9D-2q0qA:
undetectable		 1mz9D-2q0qA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfv ISOCITRATE
DEHYDROGENASE [NADP]

(Saccharomyces
cerevisiae) 		PF00180
(Iso_dh) 		4 THR A 394
LEU A 398
VAL A 401
LEU A 405
 None
 0.76A 1mz9D-2qfvA:
undetectable		 1mz9D-2qfvA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w83 C-JUN-AMINO-TERMINAL
KINASE-INTERACTING
PROTEIN 4

(Homo sapiens) 		PF16471
(JIP_LZII) 		4 THR C 409
LEU C 413
VAL C 416
LEU C 420
 None
 0.75A 1mz9D-2w83C:
4.2		 1mz9D-2w83C:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y69 CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1

(Bos taurus) 		PF02238
(COX7a) 		4 THR J  27
LEU J  31
VAL J  34
LEU J  38
 None
 0.78A 1mz9D-2y69J:
3.1		 1mz9D-2y69J:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bb7 INTERPAIN A

(Prevotella
intermedia) 		PF01640
(Peptidase_C10)
PF13734
(Inhibitor_I69) 		4 THR A 130
LEU A 128
VAL A 308
LEU A 289
 None
 0.89A 1mz9D-3bb7A:
undetectable		 1mz9D-3bb7A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bba INTERPAIN A

(Prevotella
intermedia) 		PF01640
(Peptidase_C10) 		4 THR A 130
LEU A 128
VAL A 308
LEU A 289
 None
 0.91A 1mz9D-3bbaA:
undetectable		 1mz9D-3bbaA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdz P450CIN

(Citrobacter
braakii) 		PF00067
(p450) 		4 THR A 243
LEU A 247
VAL A 250
LEU A 254
 HEM  A 450 (-4.3A)
None
None
None
 0.79A 1mz9D-3bdzA:
undetectable		 1mz9D-3bdzA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bv4 FRUCTOSE-BISPHOSPHAT
E ALDOLASE A

(Oryctolagus
cuniculus) 		PF00274
(Glycolytic) 		4 THR A 205
LEU A 209
VAL A 212
LEU A 216
 None
 0.70A 1mz9D-3bv4A:
undetectable		 1mz9D-3bv4A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8t FUMARATE LYASE

(Chelativorans
sp. BNC1) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 THR A 247
LEU A 251
VAL A 254
LEU A 258
 None
 0.79A 1mz9D-3c8tA:
undetectable		 1mz9D-3c8tA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2

(Rattus
norvegicus) 		PF01150
(GDA1_CD39) 		4 THR A 136
LEU A 140
VAL A 143
LEU A 147
 None
 0.76A 1mz9D-3cj1A:
undetectable		 1mz9D-3cj1A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csk PROBABLE
DIPEPTIDYL-PEPTIDASE
3

(Saccharomyces
cerevisiae) 		PF03571
(Peptidase_M49) 		4 THR A  84
LEU A  88
VAL A  91
LEU A  95
 None
 0.68A 1mz9D-3cskA:
1.4		 1mz9D-3cskA:
4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3s L-2,4-DIAMINOBUTYRIC
ACID
ACETYLTRANSFERASE

(Bordetella
parapertussis) 		PF00583
(Acetyltransf_1) 		4 THR A  65
LEU A  63
VAL A  69
LEU A 106
 None
 0.87A 1mz9D-3d3sA:
undetectable		 1mz9D-3d3sA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3doc GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Brucella
abortus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 154
LEU A 158
VAL A 161
LEU A 165
 None
 0.95A 1mz9D-3docA:
undetectable		 1mz9D-3docA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e97 TRANSCRIPTIONAL
REGULATOR, CRP/FNR
FAMILY

(Deinococcus
geothermalis) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 THR A 147
LEU A 151
VAL A 154
LEU A 158
 None
 0.57A 1mz9D-3e97A:
undetectable		 1mz9D-3e97A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6p TRANSCRIPTIONAL
REGULATORY PROTEIN
YYCF

(Bacillus
subtilis) 		PF00072
(Response_reg) 		4 THR A 106
LEU A 110
VAL A 113
LEU A 117
 None
 0.80A 1mz9D-3f6pA:
undetectable		 1mz9D-3f6pA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE

(Ruegeria
pomeroyi) 		PF01380
(SIS) 		4 THR A 185
LEU A 182
VAL A  19
LEU A  22
 None
 0.98A 1mz9D-3fj1A:
undetectable		 1mz9D-3fj1A:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kol GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Nostoc
punctiforme) 		PF00903
(Glyoxalase) 		4 THR A  54
LEU A  55
VAL A  64
LEU A  77
 None
 0.99A 1mz9D-3kolA:
undetectable		 1mz9D-3kolA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksd GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1

(Staphylococcus
aureus) 		no annotation 4 THR Q 152
LEU Q 156
VAL Q 159
LEU Q 163
 None
 0.96A 1mz9D-3ksdQ:
undetectable		 1mz9D-3ksdQ:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx6 FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Babesia bovis) 		PF00274
(Glycolytic) 		4 THR A 204
LEU A 208
VAL A 211
LEU A 215
 None
 0.67A 1mz9D-3kx6A:
undetectable		 1mz9D-3kx6A:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE

(Klebsiella
pneumoniae) 		PF00266
(Aminotran_5) 		4 THR A 379
LEU A 383
VAL A 386
LEU A 390
 None
 0.92A 1mz9D-3nnkA:
undetectable		 1mz9D-3nnkA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvl 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Trypanosoma
brucei) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		4 THR A 435
LEU A 439
VAL A 442
LEU A 446
 None
 0.62A 1mz9D-3nvlA:
undetectable		 1mz9D-3nvlA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3odw RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 1

(Homo sapiens) 		PF00621
(RhoGEF) 		4 THR A 655
LEU A 654
VAL A 668
LEU A 670
 None
 0.96A 1mz9D-3odwA:
undetectable		 1mz9D-3odwA:
6.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens) 		PF00563
(EAL)
PF00990
(GGDEF) 		4 THR A 289
LEU A 293
VAL A 296
LEU A 300
 None
 0.63A 1mz9D-3pjxA:
undetectable		 1mz9D-3pjxA:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6k ACETYLGLUTAMATE
KINASE

(Xanthomonas
campestris) 		PF00696
(AA_kinase)
PF04768
(NAT) 		4 THR A 272
LEU A 213
VAL A  52
LEU A  53
 None
 0.94A 1mz9D-3s6kA:
undetectable		 1mz9D-3s6kA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sho TRANSCRIPTIONAL
REGULATOR, RPIR
FAMILY

(Sphaerobacter
thermophilus) 		PF01380
(SIS) 		4 THR A 235
LEU A 247
VAL A 250
LEU A 254
 None
 0.81A 1mz9D-3shoA:
undetectable		 1mz9D-3shoA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3thz DNA MISMATCH REPAIR
PROTEIN MSH2

(Homo sapiens) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		4 THR A 905
LEU A 908
VAL A 891
LEU A 888
 None
 0.95A 1mz9D-3thzA:
undetectable		 1mz9D-3thzA:
4.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3un1 PROBABLE
OXIDOREDUCTASE

(Sinorhizobium
meliloti) 		PF13561
(adh_short_C2) 		4 THR A 149
LEU A 153
VAL A 156
LEU A 160
 None
 0.97A 1mz9D-3un1A:
undetectable		 1mz9D-3un1A:
11.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v2p CARTILAGE
OLIGOMERIZATION
MATRIX PROTEIN
(COILED-COIL DOMAIN)

(Mus musculus) 		PF11598
(COMP) 		4 THR A  40
LEU A  44
VAL A  47
LEU A  51
 STE  A   1 (-4.0A)
STE  A   1 ( 4.5A)
None
STE  A   1 (-4.4A)
 0.39A 1mz9D-3v2pA:
5.7		 1mz9D-3v2pA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wc3 ENDO-1,
4-BETA-GLUCANASE

(Eisenia fetida) 		PF00759
(Glyco_hydro_9) 		4 THR A 288
LEU A 291
VAL A 294
LEU A 298
 GOL  A 506 (-4.7A)
GOL  A 506 ( 4.4A)
None
None
 0.96A 1mz9D-3wc3A:
undetectable		 1mz9D-3wc3A:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgx CHROMOSOME PARTITION
PROTEIN SMC

(Bacillus
subtilis) 		PF02463
(SMC_N) 		4 THR A 184
LEU A 188
VAL A 191
LEU A 195
 None
 0.56A 1mz9D-3zgxA:
1.7		 1mz9D-3zgxA:
5.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b4u BIFUNCTIONAL PROTEIN
FOLD

(Acinetobacter
baumannii) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		4 THR A  29
LEU A  25
VAL A  22
LEU A  18
 None
 0.98A 1mz9D-4b4uA:
undetectable		 1mz9D-4b4uA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8b GENERAL NEGATIVE
REGULATOR OF
TRANSCRIPTION
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF16417
(CNOT1_TTP_bind)
PF16418
(CNOT1_HEAT)
PF16419
(CNOT1_HEAT_N) 		4 THR A 465
LEU A 462
VAL A 471
LEU A 475
 None
 0.96A 1mz9D-4b8bA:
undetectable		 1mz9D-4b8bA:
6.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d2j FRUCTOSE-BISPHOSPHAT
E ALDOLASE

(Toxoplasma
gondii) 		PF00274
(Glycolytic) 		4 THR A 277
LEU A 281
VAL A 284
LEU A 288
 None
 0.71A 1mz9D-4d2jA:
undetectable		 1mz9D-4d2jA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dib GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Bacillus
anthracis) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 152
LEU A 156
VAL A 159
LEU A 163
 None
 0.80A 1mz9D-4dibA:
undetectable		 1mz9D-4dibA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gpd APO-D-GLYCERALDEHYDE
-3-PHOSPHATE
DEHYDROGENASE

(Homarus
americanus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR 1 149
LEU 1 153
VAL 1 156
LEU 1 160
 None
 0.96A 1mz9D-4gpd1:
undetectable		 1mz9D-4gpd1:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxb SORTING NEXIN-17

(Homo sapiens) 		no annotation 4 THR A 139
LEU A 143
VAL A 146
LEU A 150
 None
 0.80A 1mz9D-4gxbA:
undetectable		 1mz9D-4gxbA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h19 MANDELATE RACEMASE

(Agrobacterium
fabrum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 THR A 103
LEU A 107
VAL A 110
LEU A 114
 CL  A 403 (-3.1A)
None
None
None
 0.96A 1mz9D-4h19A:
undetectable		 1mz9D-4h19A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hkg PHOSPHOPANTETHEINE
ATTACHMENT SITE
FAMILY PROTEIN

(Acinetobacter
baumannii) 		PF00550
(PP-binding) 		4 THR A  34
LEU A  38
VAL A  16
LEU A  15
 MRD  A 100 (-4.2A)
None
None
None
 0.85A 1mz9D-4hkgA:
undetectable		 1mz9D-4hkgA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpm BCL-6
COREPRESSOR-LIKE
PROTEIN 1

(Homo sapiens) 		PF16553
(PUFD) 		4 THR A1667
LEU A1666
VAL A1660
LEU A1611
 None
 0.99A 1mz9D-4hpmA:
undetectable		 1mz9D-4hpmA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l9a PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1393C

(Streptococcus
mutans) 		no annotation 4 THR A 258
LEU A 262
VAL A 265
LEU A 269
 None
 0.67A 1mz9D-4l9aA:
undetectable		 1mz9D-4l9aA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxi MCP HYDROLASE

(Sphingomonas
wittichii) 		PF12697
(Abhydrolase_6) 		4 THR A  84
LEU A  87
VAL A  31
LEU A  30
 None
 0.92A 1mz9D-4lxiA:
undetectable		 1mz9D-4lxiA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ot9 NUCLEAR FACTOR
NF-KAPPA-B P100
SUBUNIT

(Homo sapiens) 		PF12796
(Ank_2) 		4 THR A 684
LEU A 687
VAL A 650
LEU A 653
 None
 0.93A 1mz9D-4ot9A:
undetectable		 1mz9D-4ot9A:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oy4 CHIMERA PROTEIN OF
CALMODULIN, GPF-LIKE
PROTEIN EOSFP, AND
MYOSIN LIGHT CHAIN
KINASE

(Gallus gallus;
Lobophyllia
hemprichii;
Rattus
norvegicus) 		PF01353
(GFP)
PF13499
(EF-hand_7) 		4 THR A  28
LEU A  31
VAL A  34
LEU A  38
 None
 0.84A 1mz9D-4oy4A:
undetectable		 1mz9D-4oy4A:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F

(Vibrio cholerae) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 THR F  12
LEU F  16
VAL F  19
LEU F  23
 None
 0.91A 1mz9D-4p6vF:
undetectable		 1mz9D-4p6vF:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pq0 FACT COMPLEX SUBUNIT
POB3

(Saccharomyces
cerevisiae) 		PF08512
(Rtt106) 		4 THR A 353
LEU A 357
VAL A 360
LEU A 364
 None
 0.97A 1mz9D-4pq0A:
undetectable		 1mz9D-4pq0A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxj C-JUN-AMINO-TERMINAL
KINASE-INTERACTING
PROTEIN 3

(Homo sapiens) 		PF16471
(JIP_LZII) 		4 THR A 433
LEU A 437
VAL A 440
LEU A 444
 None
 0.80A 1mz9D-4pxjA:
4.7		 1mz9D-4pxjA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q65 DIPEPTIDE PERMEASE D

(Escherichia
coli) 		PF00854
(PTR2) 		4 THR A 463
LEU A 467
VAL A 470
LEU A 474
 None
 0.71A 1mz9D-4q65A:
undetectable		 1mz9D-4q65A:
7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r94 NON-STRUCTURAL
PROTEIN NS1

(Rodent
protoparvovirus
1) 		PF12433
(PV_NSP1) 		4 THR A 166
LEU A 165
VAL A 158
LEU A 157
 None
 0.94A 1mz9D-4r94A:
undetectable		 1mz9D-4r94A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rlv ANKYRIN-1, ANKYRIN-2

(Homo sapiens;
Mus musculus) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5) 		4 THR A2381
LEU A2384
VAL A2348
LEU A2351
 None
 0.95A 1mz9D-4rlvA:
undetectable		 1mz9D-4rlvA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tpn PUTATIVE P450-LIKE
PROTEIN

(Streptomyces
scabiei) 		PF00067
(p450) 		4 THR A 235
LEU A 239
VAL A 242
LEU A 246
 None
None
HEM  A 501 ( 4.1A)
HEM  A 501 ( 4.8A)
 0.67A 1mz9D-4tpnA:
undetectable		 1mz9D-4tpnA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9i PERIPLASMIC [NIFE]
HYDROGENASE LARGE
SUBUNIT

(Desulfovibrio
vulgaris) 		PF00374
(NiFeSe_Hases) 		4 THR L 162
LEU L 167
VAL L 170
LEU L 174
 None
None
MPD  S2008 ( 4.4A)
None
 0.78A 1mz9D-4u9iL:
undetectable		 1mz9D-4u9iL:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uis GAMMA-SECRETASE

(Homo sapiens) 		PF05450
(Nicastrin) 		4 THR A 483
LEU A 487
VAL A 490
LEU A 494
 None
 0.74A 1mz9D-4uisA:
undetectable		 1mz9D-4uisA:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upk PHOSPHONATE
MONOESTER HYDROLASE

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase) 		4 THR A 276
LEU A 280
VAL A 283
LEU A 287
 None
 0.75A 1mz9D-4upkA:
undetectable		 1mz9D-4upkA:
4.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4utg SUGAR KINASE

(Burkholderia
pseudomallei) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 THR A 321
LEU A 318
VAL A 203
LEU A 202
 None
 0.97A 1mz9D-4utgA:
undetectable		 1mz9D-4utgA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbd BSHC

(Bacillus
subtilis) 		PF10079
(BshC) 		4 THR A 193
LEU A 197
VAL A 200
LEU A 204
 None
 0.59A 1mz9D-4wbdA:
undetectable		 1mz9D-4wbdA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xr9 CALS8

(Micromonospora
echinospora) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		4 THR A  47
LEU A  51
VAL A  67
LEU A  70
 NAD  A 501 ( 4.5A)
None
None
None
 0.85A 1mz9D-4xr9A:
undetectable		 1mz9D-4xr9A:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xtl SODIUM PUMPING
RHODOPSIN

(Dokdonia
eikasta) 		PF01036
(Bac_rhodopsin) 		4 THR A 216
LEU A 217
VAL A 246
LEU A 245
 LFA  A 330 (-3.6A)
LFA  A 330 ( 4.8A)
None
None
 0.90A 1mz9D-4xtlA:
undetectable		 1mz9D-4xtlA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y21 PROTEIN UNC-13
HOMOLOG A

(Rattus
norvegicus) 		PF06292
(DUF1041)
PF10540
(Membr_traf_MHD) 		4 THR A  58
LEU A  54
VAL A  51
LEU A  47
 None
 0.93A 1mz9D-4y21A:
undetectable		 1mz9D-4y21A:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z2a FURIN

(Homo sapiens) 		PF00082
(Peptidase_S8)
PF01483
(P_proprotein) 		4 THR A 340
LEU A 429
VAL A 397
LEU A 396
 None
 0.95A 1mz9D-4z2aA:
undetectable		 1mz9D-4z2aA:
6.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7d LYSR FAMILY
TRANSCRIPTIONAL
REGULATOR

(Vibrio
vulnificus) 		PF03466
(LysR_substrate) 		4 THR A 289
LEU A 293
VAL A 296
LEU A 300
 None
 0.78A 1mz9D-5b7dA:
undetectable		 1mz9D-5b7dA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c65 SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 3

(Homo sapiens) 		PF00083
(Sugar_tr) 		4 THR A 156
LEU A 160
VAL A 163
LEU A 167
 None
 0.73A 1mz9D-5c65A:
undetectable		 1mz9D-5c65A:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ck3 PUTATIVE SIGNAL
RECOGNITION PARTICLE
PROTEIN

(Chaetomium
thermophilum) 		PF09439
(SRPRB) 		4 THR B 216
LEU B 220
VAL B 223
LEU B 227
 None
 0.90A 1mz9D-5ck3B:
undetectable		 1mz9D-5ck3B:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cqs ELONGATOR COMPLEX
PROTEIN 1

(Saccharomyces
cerevisiae) 		PF04762
(IKI3) 		4 THR A1269
LEU A1266
VAL A1299
LEU A1302
 None
 0.94A 1mz9D-5cqsA:
undetectable		 1mz9D-5cqsA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cs4 ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF08326
(ACC_central) 		4 THR A1229
LEU A1183
VAL A1186
LEU A1190
 None
 0.94A 1mz9D-5cs4A:
undetectable		 1mz9D-5cs4A:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csa ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00364
(Biotin_lipoyl)
PF08326
(ACC_central) 		4 THR A1229
LEU A1183
VAL A1186
LEU A1190
 None
 0.97A 1mz9D-5csaA:
undetectable		 1mz9D-5csaA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csl ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF01039
(Carboxyl_trans)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
PF08326
(ACC_central) 		4 THR A1229
LEU A1183
VAL A1186
LEU A1190
 None
 0.88A 1mz9D-5cslA:
undetectable		 1mz9D-5cslA:
2.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzt CYLM

(Enterococcus
faecalis) 		PF05147
(LANC_like)
PF13575
(DUF4135) 		4 THR A 218
LEU A 222
VAL A 225
LEU A 229
 None
 0.60A 1mz9D-5dztA:
undetectable		 1mz9D-5dztA:
4.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ee5 BREFELDIN
A-INHIBITED GUANINE
NUCLEOTIDE-EXCHANGE
PROTEIN 1

(Homo sapiens) 		PF16213
(DCB) 		4 THR A 199
LEU A 202
VAL A 175
LEU A 172
 ALY  A 195 ( 3.5A)
CL  A 308 (-4.0A)
None
None
 0.91A 1mz9D-5ee5A:
undetectable		 1mz9D-5ee5A:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqi SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 1

(Homo sapiens) 		PF00083
(Sugar_tr) 		4 THR A 158
LEU A 162
VAL A 165
LEU A 169
 None
 0.80A 1mz9D-5eqiA:
undetectable		 1mz9D-5eqiA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f8e METHYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF13847
(Methyltransf_31) 		4 THR A  95
LEU A  37
VAL A  28
LEU A  27
 None
 0.89A 1mz9D-5f8eA:
undetectable		 1mz9D-5f8eA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fn4 NICASTRIN

(Homo sapiens) 		PF05450
(Nicastrin) 		4 THR A 483
LEU A 487
VAL A 490
LEU A 494
 None
 0.73A 1mz9D-5fn4A:
undetectable		 1mz9D-5fn4A:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqd DNA DAMAGE-BINDING
PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 THR A1125
LEU A1129
VAL A1132
LEU A1136
 None
 0.94A 1mz9D-5fqdA:
undetectable		 1mz9D-5fqdA:
5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN

(Streptococcus
suis) 		PF05670
(DUF814)
PF05833
(FbpA) 		4 THR A 117
LEU A 121
VAL A 124
LEU A 128
 None
 0.66A 1mz9D-5h3wA:
2.8		 1mz9D-5h3wA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h67 CHROMOSOME PARTITION
PROTEIN SMC

(Bacillus
subtilis) 		PF02463
(SMC_N) 		4 THR A 184
LEU A 188
VAL A 191
LEU A 195
 None
 0.94A 1mz9D-5h67A:
1.9		 1mz9D-5h67A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i51 TRANSKETOLASE

(Scheffersomyces
stipitis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 THR A 386
LEU A 363
VAL A 362
LEU A 343
 None
 0.88A 1mz9D-5i51A:
undetectable		 1mz9D-5i51A:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6e ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF08326
(ACC_central) 		4 THR A1229
LEU A1183
VAL A1186
LEU A1190
 None
 0.94A 1mz9D-5i6eA:
undetectable		 1mz9D-5i6eA:
4.17