SIMILAR PATTERNS OF AMINO ACIDS FOR 1MZ9_A_VDYA1002_5
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a3x | PYRUVATE KINASE (Saccharomycescerevisiae) |
PF00224(PK)PF02887(PK_C) | 4 | LEU A 267VAL A 262CYH A 296ALA A 321 | None | 1.21A | 1mz9E-1a3xA:0.0 | 1mz9E-1a3xA:7.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gq7 | PROCLAVAMINATEAMIDINO HYDROLASE (Streptomycesclavuligerus) |
PF00491(Arginase) | 4 | LEU A 301VAL A 267CYH A 266ALA A 218 | None | 1.08A | 1mz9E-1gq7A:0.0 | 1mz9E-1gq7A:9.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ig0 | THIAMINPYROPHOSPHOKINASE (Saccharomycescerevisiae) |
PF04263(TPK_catalytic)PF04265(TPK_B1_binding) | 4 | LEU A 64VAL A 66CYH A 67ALA A 72 | None | 1.20A | 1mz9E-1ig0A:0.0 | 1mz9E-1ig0A:8.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jax | CONSERVEDHYPOTHETICAL PROTEIN (Archaeoglobusfulgidus) |
PF03807(F420_oxidored) | 4 | LEU A 167VAL A 3CYH A 65ALA A 62 | None | 1.05A | 1mz9E-1jaxA:0.0 | 1mz9E-1jaxA:12.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kol | FORMALDEHYDEDEHYDROGENASE (Pseudomonasputida) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 250VAL A 255CYH A 257ALA A 181 | None | 1.22A | 1mz9E-1kolA:0.0 | 1mz9E-1kolA:7.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m54 | CYSTATHIONINEBETA-SYNTHASE (Homo sapiens) |
PF00291(PALP) | 4 | LEU A 374VAL A 372CYH A 370ALA A 361 | None | 1.28A | 1mz9E-1m54A:0.0 | 1mz9E-1m54A:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mo2 | ERYTHRONOLIDESYNTHASE, MODULES 5AND 6 (Saccharopolysporaerythraea) |
PF00975(Thioesterase) | 4 | LEU A 56VAL A 101CYH A 73ALA A 148 | None | 1.29A | 1mz9E-1mo2A:0.0 | 1mz9E-1mo2A:9.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rw9 | CHONDROITIN AC LYASE (Paenarthrobacteraurescens) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 4 | LEU A 246VAL A 185CYH A 188ALA A 207 | None | 1.17A | 1mz9E-1rw9A:0.0 | 1mz9E-1rw9A:4.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tjr | BX1 (Zea mays) |
PF00290(Trp_syntA) | 4 | LEU A 170VAL A 181CYH A 179ALA A 130 | None | 1.21A | 1mz9E-1tjrA:0.0 | 1mz9E-1tjrA:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vm6 | DIHYDRODIPICOLINATEREDUCTASE (Thermotogamaritima) |
PF01113(DapB_N)PF05173(DapB_C) | 4 | LEU A 54VAL A 58CYH A 61ALA A 66 | None | 1.12A | 1mz9E-1vm6A:undetectable | 1mz9E-1vm6A:12.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wl4 | ACETYL-COENZYME AACETYLTRANSFERASE 2 (Homo sapiens) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | LEU A 370VAL A 394CYH A 393ALA A 304 | None | 1.29A | 1mz9E-1wl4A:undetectable | 1mz9E-1wl4A:9.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a2d | N-ACETYLGALACTOSAMINE KINASE (Homo sapiens) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 4 | LEU A 382VAL A 386CYH A 389ALA A 394 | None | 1.28A | 1mz9E-2a2dA:undetectable | 1mz9E-2a2dA:7.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2af4 | PHOSPHATEACETYLTRANSFERASE (Methanosarcinathermophila) |
PF01515(PTA_PTB) | 4 | LEU C 21VAL C 321CYH C 325ALA C 12 | None | 1.29A | 1mz9E-2af4C:undetectable | 1mz9E-2af4C:9.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2af4 | PHOSPHATEACETYLTRANSFERASE (Methanosarcinathermophila) |
PF01515(PTA_PTB) | 4 | LEU C 197VAL C 326CYH C 325ALA C 42 | None | 1.13A | 1mz9E-2af4C:undetectable | 1mz9E-2af4C:9.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b7h | HEMOGLOBIN ALPHACHAINHEMOGLOBIN BETACHAIN (Cerdocyon thous) |
PF00042(Globin) | 4 | LEU B 105VAL B 109CYH B 112ALA A 110 | None | 1.11A | 1mz9E-2b7hB:undetectable | 1mz9E-2b7hB:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fk6 | RIBONUCLEASE Z (Bacillussubtilis) |
PF12706(Lactamase_B_2) | 4 | LEU A 3VAL A 206CYH A 225ALA A 222 | None | 1.13A | 1mz9E-2fk6A:undetectable | 1mz9E-2fk6A:10.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hfs | MEVALONATE KINASE,PUTATIVE (Leishmaniamajor) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | LEU A 263VAL A 267CYH A 270ALA A 275 | None | 1.10A | 1mz9E-2hfsA:undetectable | 1mz9E-2hfsA:8.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hwk | HELICASE NSP2 (Venezuelanequineencephalitisvirus) |
PF01707(Peptidase_C9) | 4 | LEU A 758VAL A 718CYH A 717ALA A 707 | None | 1.25A | 1mz9E-2hwkA:undetectable | 1mz9E-2hwkA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2irw | CORTICOSTEROID11-BETA-DEHYDROGENASE ISOZYME 1 (Homo sapiens) |
PF00106(adh_short) | 4 | LEU A 71VAL A 75CYH A 78ALA A 55 | None | 1.08A | 1mz9E-2irwA:undetectable | 1mz9E-2irwA:12.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2irw | CORTICOSTEROID11-BETA-DEHYDROGENASE ISOZYME 1 (Homo sapiens) |
PF00106(adh_short) | 4 | LEU A 71VAL A 75CYH A 78ALA A 83 | None | 1.08A | 1mz9E-2irwA:undetectable | 1mz9E-2irwA:12.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ji4 | PHOSPHORIBOSYLPYROPHOSPHATESYNTHETASE-ASSOCIATED PROTEIN 2 (Homo sapiens) |
PF13793(Pribosyltran_N)PF14572(Pribosyl_synth) | 4 | LEU A 89VAL A 93CYH A 96ALA A 101 | None | 0.94A | 1mz9E-2ji4A:undetectable | 1mz9E-2ji4A:9.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l7b | APOLIPOPROTEIN E (Homo sapiens) |
PF01442(Apolipoprotein) | 4 | LEU A 37VAL A 111CYH A 112ALA A 193 | None | 1.25A | 1mz9E-2l7bA:undetectable | 1mz9E-2l7bA:9.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2le1 | UNCHARACTERIZEDPROTEIN (Thermobifidafusca) |
PF10604(Polyketide_cyc2) | 4 | LEU A 93VAL A 95CYH A 103ALA A 12 | None | 1.23A | 1mz9E-2le1A:undetectable | 1mz9E-2le1A:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odf | HYPOTHETICAL PROTEINATU2144 (Agrobacteriumfabrum) |
PF05013(FGase) | 4 | LEU A 28VAL A 30CYH A 31ALA A 34 | None | 1.22A | 1mz9E-2odfA:undetectable | 1mz9E-2odfA:9.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2prd | PYROPHOSPHATEPHOSPHOHYDROLASE (Thermusthermophilus) |
PF00719(Pyrophosphatase) | 4 | LEU A 162VAL A 165CYH A 168ALA A 63 | None | 1.08A | 1mz9E-2prdA:undetectable | 1mz9E-2prdA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uzg | UBIQUITINCARBOXYL-TERMINALHYDROLASE 33 (Homo sapiens) |
PF02148(zf-UBP) | 4 | LEU A 123VAL A 121CYH A 114ALA A 116 | NoneNone ZN A 131 (-2.3A) ZN A 131 ( 4.4A) | 1.29A | 1mz9E-2uzgA:undetectable | 1mz9E-2uzgA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vgi | PYRUVATE KINASEISOZYMES R/L (Homo sapiens) |
PF00224(PK)PF02887(PK_C) | 4 | LEU A 340VAL A 335CYH A 369ALA A 394 | None | 1.04A | 1mz9E-2vgiA:undetectable | 1mz9E-2vgiA:6.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vgi | PYRUVATE KINASEISOZYMES R/L (Homo sapiens) |
PF00224(PK)PF02887(PK_C) | 4 | LEU A 340VAL A 335CYH A 369ALA A 399 | None | 1.20A | 1mz9E-2vgiA:undetectable | 1mz9E-2vgiA:6.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wnr | PROBABLE EXOSOMECOMPLEX EXONUCLEASE2 (Methanothermobacterthermautotrophicus) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 4 | LEU A 107VAL A 111CYH A 114ALA A 193 | None | 0.94A | 1mz9E-2wnrA:undetectable | 1mz9E-2wnrA:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x3e | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Pseudomonasaeruginosa) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | LEU A 176VAL A 7CYH A 8ALA A 67 | None | 0.93A | 1mz9E-2x3eA:undetectable | 1mz9E-2x3eA:8.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ynm | LIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT N (Prochlorococcusmarinus) |
PF00148(Oxidored_nitro) | 4 | LEU C 288VAL C 360CYH C 361ALA C 366 | None | 1.28A | 1mz9E-2ynmC:undetectable | 1mz9E-2ynmC:7.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zm2 | 6-AMINOHEXANOATE-DIMER HYDROLASE (Flavobacteriumsp.) |
PF00144(Beta-lactamase) | 4 | LEU A 125VAL A 121CYH A 118ALA A 265 | None | 1.09A | 1mz9E-2zm2A:undetectable | 1mz9E-2zm2A:7.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bcv | PUTATIVEGLYCOSYLTRANSFERASEPROTEIN (Bacteroidesfragilis) |
PF00535(Glycos_transf_2) | 4 | LEU A 208VAL A 214CYH A 114ALA A 109 | None | 1.26A | 1mz9E-3bcvA:undetectable | 1mz9E-3bcvA:8.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cos | ALCOHOLDEHYDROGENASE 4 (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 206VAL A 214CYH A 217ALA A 222 | None | 1.13A | 1mz9E-3cosA:undetectable | 1mz9E-3cosA:7.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dwf | 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 (Cavia porcellus) |
PF00106(adh_short) | 4 | LEU A 71VAL A 75CYH A 78ALA A 55 | None | 1.08A | 1mz9E-3dwfA:undetectable | 1mz9E-3dwfA:10.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dwf | 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 (Cavia porcellus) |
PF00106(adh_short) | 4 | LEU A 71VAL A 75CYH A 78ALA A 83 | None | 1.14A | 1mz9E-3dwfA:undetectable | 1mz9E-3dwfA:10.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9k | INTEGRASE (Humanimmunodeficiencyvirus 2) |
PF00665(rve)PF02022(Integrase_Zn) | 4 | LEU A 22VAL A 37CYH A 40ALA A 41 | NoneNone ZN A 210 (-2.1A)None | 1.25A | 1mz9E-3f9kA:undetectable | 1mz9E-3f9kA:14.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fcj | NITROALKANE OXIDASE (Fusariumoxysporum) |
PF00441(Acyl-CoA_dh_1)PF02771(Acyl-CoA_dh_N) | 4 | LEU A 131VAL A 187CYH A 188ALA A 154 | None | 1.27A | 1mz9E-3fcjA:undetectable | 1mz9E-3fcjA:7.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fcn | AN ALPHA-HELICALPROTEIN OF UNKNOWNFUNCTION (PFAM01724) (Rhodospirillumrubrum) |
PF01724(DUF29) | 4 | LEU A 146VAL A 61CYH A 65ALA A 115 | None | 1.17A | 1mz9E-3fcnA:undetectable | 1mz9E-3fcnA:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fj1 | PUTATIVEPHOSPHOSUGARISOMERASE (Ruegeriapomeroyi) |
PF01380(SIS) | 4 | LEU A 123VAL A 121CYH A 120ALA A 118 | None | 1.20A | 1mz9E-3fj1A:undetectable | 1mz9E-3fj1A:8.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hba | PUTATIVEPHOSPHOSUGARISOMERASE (Shewanelladenitrificans) |
PF01380(SIS) | 4 | LEU A 122VAL A 120CYH A 119ALA A 117 | None | 1.15A | 1mz9E-3hbaA:undetectable | 1mz9E-3hbaA:11.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ipi | GERANYLTRANSTRANSFERASE (Methanosarcinamazei) |
PF00348(polyprenyl_synt) | 4 | LEU A 280VAL A 61CYH A 65ALA A 192 | NoneNoneMLA A 309 (-4.4A)None | 1.14A | 1mz9E-3ipiA:undetectable | 1mz9E-3ipiA:10.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jzd | IRON-CONTAININGALCOHOLDEHYDROGENASE (Cupriaviduspinatubonensis) |
PF00465(Fe-ADH) | 4 | LEU A 158VAL A 95CYH A 42ALA A 66 | None | 0.82A | 1mz9E-3jzdA:undetectable | 1mz9E-3jzdA:6.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1j | ATP-DEPENDENTPROTEASE LON (Thermococcusonnurineus) |
PF01078(Mg_chelatase)PF05362(Lon_C)PF13654(AAA_32) | 4 | LEU A 185VAL A 286CYH A 288ALA A 261 | None | 1.17A | 1mz9E-3k1jA:undetectable | 1mz9E-3k1jA:7.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n23 | SODIUM/POTASSIUM-TRANSPORTING ATPASESUBUNIT ALPHA-1 (Sus scrofa) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF13246(Cation_ATPase) | 4 | LEU A 330VAL A 333CYH A 336ALA A 816 | None | 1.29A | 1mz9E-3n23A:undetectable | 1mz9E-3n23A:4.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ngw | MOLYBDOPTERIN-GUANINE DINUCLEOTIDEBIOSYNTHESIS PROTEINA (MOBA) (Archaeoglobusfulgidus) |
PF12804(NTP_transf_3) | 4 | LEU A 153VAL A 158CYH A 113ALA A 111 | None | 0.89A | 1mz9E-3ngwA:undetectable | 1mz9E-3ngwA:11.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3om9 | LACTATEDEHYDROGENASE (Toxoplasmagondii) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | LEU A 202VAL A 191CYH A 165ALA A 164 | NoneNoneNoneNAD A 701 (-3.7A) | 1.19A | 1mz9E-3om9A:undetectable | 1mz9E-3om9A:11.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pl0 | UNCHARACTERIZEDPROTEIN (Methylibiumpetroleiphilum) |
PF10014(2OG-Fe_Oxy_2) | 4 | LEU A 202VAL A 25CYH A 24ALA A 14 | None | 1.19A | 1mz9E-3pl0A:undetectable | 1mz9E-3pl0A:12.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t8q | MANDELATERACEMASE/MUCONATELACTONIZING ENZYMEFAMILY PROTEIN (Hoefleaphototrophica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 85VAL A 17CYH A 15ALA A 10 | None | 1.15A | 1mz9E-3t8qA:undetectable | 1mz9E-3t8qA:7.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tmq | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE 2 (Burkholderiapseudomallei) |
PF00793(DAHP_synth_1) | 4 | LEU A 146VAL A 150CYH A 153ALA A 127 | None | 1.20A | 1mz9E-3tmqA:undetectable | 1mz9E-3tmqA:10.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zt9 | SERINE PHOSPHATASE (Moorellathermoacetica) |
PF07228(SpoIIE) | 4 | LEU A 4VAL A 89CYH A 87ALA A 98 | None | 1.06A | 1mz9E-3zt9A:undetectable | 1mz9E-3zt9A:13.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4axg | EUKARYOTICTRANSLATIONINITIATION FACTOR 4E (Drosophilamelanogaster) |
PF01652(IF4E) | 4 | LEU A 161VAL A 165CYH A 168ALA A 173 | None | 0.99A | 1mz9E-4axgA:undetectable | 1mz9E-4axgA:13.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b0n | POLYKETIDE SYNTHASEIII (Ectocarpussiliculosus) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | LEU A 135VAL A 221CYH A 220ALA A 197 | None | 1.28A | 1mz9E-4b0nA:undetectable | 1mz9E-4b0nA:11.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c90 | ALPHA-GLUCURONIDASEGH115 (Bacteroidesovatus) |
PF15979(Glyco_hydro_115) | 4 | LEU A 466VAL A 232CYH A 233ALA A 264 | None | 1.25A | 1mz9E-4c90A:undetectable | 1mz9E-4c90A:4.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ci8 | ECHINODERMMICROTUBULE-ASSOCIATED PROTEIN-LIKE 1 (Homo sapiens) |
PF00400(WD40)PF03451(HELP) | 4 | LEU A 405VAL A 355CYH A 343ALA A 332 | None | 1.28A | 1mz9E-4ci8A:undetectable | 1mz9E-4ci8A:6.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cv5 | PROTEIN CAF40 (Saccharomycescerevisiae) |
PF04078(Rcd1) | 4 | LEU B 245VAL B 250CYH B 253ALA B 268 | None | 1.10A | 1mz9E-4cv5B:undetectable | 1mz9E-4cv5B:11.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ecn | LEUCINE-RICH REPEATPROTEIN (Bacteroidesthetaiotaomicron) |
PF14660(DUF4458) | 4 | LEU A 853VAL A 872CYH A 897ALA A 899 | None | 1.13A | 1mz9E-4ecnA:undetectable | 1mz9E-4ecnA:5.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3n | UNCHARACTERIZED ACR,COG1565 SUPERFAMILY (Burkholderiathailandensis) |
PF02636(Methyltransf_28) | 4 | LEU A 195VAL A 260CYH A 264ALA A 333 | None | 0.99A | 1mz9E-4f3nA:undetectable | 1mz9E-4f3nA:7.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzw | 1,2-EPOXYPHENYLACETYL-COA ISOMERASE (Escherichiacoli) |
PF00378(ECH_1) | 4 | LEU C 95VAL C 102CYH C 50ALA C 198 | None | 1.14A | 1mz9E-4fzwC:undetectable | 1mz9E-4fzwC:11.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g1u | HEMIN TRANSPORTSYSTEM PERMEASEPROTEIN HMUU (Yersinia pestis) |
PF01032(FecCD) | 4 | LEU A 60VAL A 64CYH A 67ALA A 284 | None | 1.29A | 1mz9E-4g1uA:undetectable | 1mz9E-4g1uA:8.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4glf | RSFP (unculturedbacterium) |
PF01048(PNP_UDP_1) | 4 | LEU A 151VAL A 147CYH A 144ALA A 269 | None | 1.00A | 1mz9E-4glfA:undetectable | 1mz9E-4glfA:10.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hyv | PYRUVATE KINASE 1 (Trypanosomabrucei) |
PF00224(PK)PF02887(PK_C) | 4 | LEU A 266VAL A 261CYH A 295ALA A 320 | None | 1.15A | 1mz9E-4hyvA:undetectable | 1mz9E-4hyvA:6.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jlw | GLUTATHIONE-INDEPENDENT FORMALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 251VAL A 256CYH A 258ALA A 182 | None | 1.24A | 1mz9E-4jlwA:undetectable | 1mz9E-4jlwA:7.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jmu | GAG-POL POLYPROTEIN (Humanimmunodeficiencyvirus 1) |
PF00540(Gag_p17) | 4 | LEU A 8VAL A 88CYH A 87ALA A 100 | None | 1.20A | 1mz9E-4jmuA:undetectable | 1mz9E-4jmuA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jn7 | ENOLASE (Agrobacteriumtumefaciens) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 261VAL A 237CYH A 236ALA A 208 | None | 1.29A | 1mz9E-4jn7A:undetectable | 1mz9E-4jn7A:7.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k26 | CORTICOSTEROID11-BETA-DEHYDROGENASE ISOZYME 1 (Mus musculus) |
PF00106(adh_short) | 4 | LEU A 71VAL A 75CYH A 78ALA A 83 | None | 1.16A | 1mz9E-4k26A:undetectable | 1mz9E-4k26A:10.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l15 | FIDGETIN-LIKEPROTEIN 1 (Caenorhabditiselegans) |
PF00004(AAA)PF09336(Vps4_C) | 4 | LEU A 457VAL A 369CYH A 368ALA A 316 | None | 0.95A | 1mz9E-4l15A:undetectable | 1mz9E-4l15A:9.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ofx | CYSTATHIONINEBETA-SYNTHASE (Coxiellaburnetii) |
PF00291(PALP) | 4 | LEU A 293VAL A 291CYH A 289ALA A 280 | None | 1.22A | 1mz9E-4ofxA:undetectable | 1mz9E-4ofxA:8.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4per | RIBONUCLEASEINHIBITOR (Gallus gallus) |
PF13516(LRR_6) | 4 | LEU A 120VAL A 125CYH A 129ALA A 160 | None | 1.21A | 1mz9E-4perA:undetectable | 1mz9E-4perA:8.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4per | RIBONUCLEASEINHIBITOR (Gallus gallus) |
PF13516(LRR_6) | 4 | LEU A 332VAL A 328CYH A 325ALA A 322 | None | 1.26A | 1mz9E-4perA:undetectable | 1mz9E-4perA:8.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdk | MAGNESIUM-PROTOPORPHYRINO-METHYLTRANSFERASE (Synechocystissp. PCC 6803) |
PF07109(Mg-por_mtran_C) | 4 | LEU A 64VAL A 66CYH A 67ALA A 69 | None | 1.24A | 1mz9E-4qdkA:undetectable | 1mz9E-4qdkA:10.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiu | NITRONATEMONOOXYGENASE FAMILYPROTEIN (Pseudomonasaeruginosa) |
PF03060(NMO) | 4 | LEU A 258VAL A 243CYH A 245ALA A 338 | None | 1.26A | 1mz9E-4qiuA:undetectable | 1mz9E-4qiuA:9.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rlt | (3R)-HYDROXYACYL-ACPDEHYDRATASE SUBUNITHADA (Mycobacteriumtuberculosis) |
PF13452(MaoC_dehydrat_N) | 4 | LEU A 134VAL A 127CYH A 105ALA A 67 | None | 1.12A | 1mz9E-4rltA:undetectable | 1mz9E-4rltA:14.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uar | PROTEIN CBBY (Rhodobactersphaeroides) |
PF13419(HAD_2) | 4 | LEU A 210VAL A 193CYH A 191ALA A 184 | None | 1.29A | 1mz9E-4uarA:undetectable | 1mz9E-4uarA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w4t | MXAA (Stigmatellaaurantiaca) |
PF07993(NAD_binding_4) | 4 | LEU A1509VAL A1363CYH A1362ALA A1368 | None | 1.11A | 1mz9E-4w4tA:undetectable | 1mz9E-4w4tA:7.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xr9 | CALS8 (Micromonosporaechinospora) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | LEU A 441VAL A 426CYH A 424ALA A 396 | None | 1.28A | 1mz9E-4xr9A:undetectable | 1mz9E-4xr9A:7.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yj5 | PYRUVATE KINASE PKM (Homo sapiens) |
PF00224(PK)PF02887(PK_C) | 4 | LEU A 297VAL A 292CYH A 326ALA A 351 | None | 1.19A | 1mz9E-4yj5A:undetectable | 1mz9E-4yj5A:5.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zht | BIFUNCTIONALUDP-N-ACETYLGLUCOSAMINE2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE (Homo sapiens) |
PF02350(Epimerase_2) | 4 | LEU A 10VAL A 12CYH A 13ALA A 15 | None | 1.29A | 1mz9E-4zhtA:undetectable | 1mz9E-4zhtA:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zpx | ATP-DEPENDENTPROTEASE LON (Thermococcusonnurineus) |
PF01078(Mg_chelatase)PF13654(AAA_32) | 4 | LEU A 185VAL A 286CYH A 288ALA A 261 | None | 1.08A | 1mz9E-4zpxA:undetectable | 1mz9E-4zpxA:8.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwe | DEOXYNUCLEOSIDETRIPHOSPHATETRIPHOSPHOHYDROLASESAMHD1 (Homo sapiens) |
PF01966(HD) | 4 | LEU A 182VAL A 340CYH A 341ALA A 529 | None | 1.25A | 1mz9E-4zweA:undetectable | 1mz9E-4zweA:7.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ahk | ACETOLACTATESYNTHASE II, LARGESUBUNIT (Pseudomonasprotegens) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | LEU A 261VAL A 273CYH A 276ALA A 302 | None | 1.22A | 1mz9E-5ahkA:undetectable | 1mz9E-5ahkA:6.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aw4 | NA, K-ATPASE ALPHASUBUNIT (Squalusacanthias) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF13246(Cation_ATPase) | 4 | LEU A 337VAL A 340CYH A 343ALA A 823 | None | 1.19A | 1mz9E-5aw4A:undetectable | 1mz9E-5aw4A:4.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5czc | MALONYL-COA-[ACYL-CARRIER-PROTEIN]TRANSACYLASE (Streptomyceshalstedii) |
no annotation | 4 | LEU A 280VAL A 288CYH A 289ALA A 312 | None | 1.26A | 1mz9E-5czcA:undetectable | 1mz9E-5czcA:11.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5flz | SPINDLE POLE BODYCOMPONENT SPC97 (Saccharomycescerevisiae) |
PF04130(Spc97_Spc98) | 4 | LEU A 390VAL A 394CYH A 397ALA A 401 | None | 0.90A | 1mz9E-5flzA:undetectable | 1mz9E-5flzA:5.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8f | ACETYL-COENZYME ASYNTHETASE (Cryptococcusneoformans) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 4 | LEU A 198VAL A 202CYH A 205ALA A 161 | None | 1.03A | 1mz9E-5k8fA:undetectable | 1mz9E-5k8fA:5.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3x | NEGATIVE ELONGATIONFACTOR C/D (Homo sapiens) |
PF04858(TH1) | 4 | LEU B 205VAL B 231CYH B 232ALA B 269 | None | 1.28A | 1mz9E-5l3xB:undetectable | 1mz9E-5l3xB:7.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mms | CYSTATHIONINEBETA-SYNTHASE (Homo sapiens) |
PF00291(PALP) | 4 | LEU A 374VAL A 372CYH A 370ALA A 361 | None | 1.17A | 1mz9E-5mmsA:undetectable | 1mz9E-5mmsA:9.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nla | PUTATIVETRANSCRIPTIONALREGULATORTRANSCRIPTIONREGULATOR PROTEIN (Sinorhizobiummeliloti) |
PF12833(HTH_18)PF14525(AraC_binding_2) | 4 | LEU A 185VAL A 235CYH A 234ALA A 198 | None | 1.23A | 1mz9E-5nlaA:undetectable | 1mz9E-5nlaA:10.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oc9 | - (-) |
no annotation | 4 | LEU A 429VAL A 514CYH A 513ALA A 247 | NoneNoneNone79M A 707 ( 3.7A) | 1.29A | 1mz9E-5oc9A:undetectable | 1mz9E-5oc9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t47 | EUKARYOTICTRANSLATIONINITIATION FACTOR 4E (Drosophilamelanogaster) |
PF01652(IF4E) | 4 | LEU A 161VAL A 165CYH A 168ALA A 173 | None | 0.93A | 1mz9E-5t47A:undetectable | 1mz9E-5t47A:10.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ud6 | DIHYDRODIPICOLINATESYNTHASE (Cyanidioschyzonmerolae) |
no annotation | 4 | LEU A 108VAL A 84CYH A 82ALA A 42 | None | 1.26A | 1mz9E-5ud6A:undetectable | 1mz9E-5ud6A:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v10 | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF03061(4HBT) | 4 | LEU A 80VAL A 100CYH A 110ALA A 68 | None | 1.08A | 1mz9E-5v10A:undetectable | 1mz9E-5v10A:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v57 | SMOOTHENEDHOMOLOG,FLAVODOXIN,SMOOTHENED HOMOLOG (Desulfovibriovulgaris;Homo sapiens) |
PF00258(Flavodoxin_1)PF01392(Fz)PF01534(Frizzled) | 4 | LEU A 267VAL A 270CYH A 273ALA A 327 | None | 1.25A | 1mz9E-5v57A:undetectable | 1mz9E-5v57A:7.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vxc | CITRATE LYASESUBUNIT BETA-LIKEPROTEIN,MITOCHONDRIAL (Homo sapiens) |
no annotation | 4 | LEU A 133VAL A 108CYH A 74ALA A 86 | None | 1.20A | 1mz9E-5vxcA:undetectable | 1mz9E-5vxcA:10.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w19 | TRYPTOPHANASE (Proteusvulgaris) |
no annotation | 4 | LEU A 339VAL A 357CYH A 359ALA A 373 | None | 1.18A | 1mz9E-5w19A:undetectable | 1mz9E-5w19A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xso | RESPONSE REGULATORFIXJ (Bradyrhizobiumjaponicum) |
no annotation | 4 | LEU A 20VAL A 53CYH A 51ALA A 119 | None | 1.23A | 1mz9E-5xsoA:undetectable | 1mz9E-5xsoA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yje | PROTEIN HIRA (Homo sapiens) |
no annotation | 4 | LEU A 768VAL A 759CYH A 749ALA A 742 | None | 0.98A | 1mz9E-5yjeA:undetectable | 1mz9E-5yjeA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ykh | PUMILIO HOMOLOG 1 (Homo sapiens) |
no annotation | 4 | LEU A 173VAL A 183CYH A 186ALA A 190 | None | 1.18A | 1mz9E-5ykhA:undetectable | 1mz9E-5ykhA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c49 | ALCOHOLDEHYDROGENASE (Acinetobacterbaumannii) |
no annotation | 4 | LEU A 237VAL A 173CYH A 194ALA A 169 | None | 1.05A | 1mz9E-6c49A:undetectable | 1mz9E-6c49A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cdd | NPL4 ZINC FINGER (Chaetomiumthermophilum) |
no annotation | 4 | LEU A 272VAL A 406CYH A 404ALA A 418 | None | 1.26A | 1mz9E-6cddA:undetectable | 1mz9E-6cddA:16.67 |