SIMILAR PATTERNS OF AMINO ACIDS FOR 1MZ9_A_VDYA1002_3

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0i D-AMINO ACID OXIDASE

(Rhodotorula
toruloides) 		PF01266
(DAO) 		4 ILE A1022
LEU A1023
VAL A1009
ALA A1168
 None
 0.96A 1mz9C-1c0iA:
0.0		 1mz9C-1c0iA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4o DNA NUCLEOTIDE
EXCISION REPAIR
ENZYME UVRB

(Thermus
thermophilus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF12344
(UvrB) 		4 LEU A 515
VAL A 445
ALA A 467
CYH A 493
 None
 0.92A 1mz9C-1c4oA:
0.0		 1mz9C-1c4oA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ce7 PROTEIN
(RIBOSOME-INACTIVATI
NG PROTEIN TYPE II)

(Viscum album) 		PF00161
(RIP) 		4 ILE A 128
LEU A 131
VAL A 135
ALA A  81
 None
 0.90A 1mz9C-1ce7A:
undetectable		 1mz9C-1ce7A:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dj2 ADENYLOSUCCINATE
SYNTHETASE

(Arabidopsis
thaliana) 		PF00709
(Adenylsucc_synt) 		4 ILE A  40
LEU A  41
VAL A  24
ALA A 263
 None
 0.83A 1mz9C-1dj2A:
0.0		 1mz9C-1dj2A:
10.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dkr PHOSPHORIBOSYL
PYROPHOSPHATE
SYNTHETASE

(Bacillus
subtilis) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		4 ILE A  72
LEU A  75
VAL A  79
ALA A  87
 None
 0.58A 1mz9C-1dkrA:
undetectable		 1mz9C-1dkrA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ece ENDOCELLULASE E1

(Acidothermus
cellulolyticus) 		PF00150
(Cellulase) 		4 ILE A 198
LEU A 196
VAL A 154
ALA A 102
 None
 0.91A 1mz9C-1eceA:
undetectable		 1mz9C-1eceA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1efy POLY (ADP-RIBOSE)
POLYMERASE

(Gallus gallus) 		PF00644
(PARP)
PF02877
(PARP_reg) 		4 ILE A 673
LEU A 672
ALA A 905
CYH A 908
 None
 0.96A 1mz9C-1efyA:
0.0		 1mz9C-1efyA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1esc ESTERASE

(Streptomyces
scabiei) 		PF13472
(Lipase_GDSL_2) 		4 ILE A 291
LEU A 245
VAL A 243
ALA A 240
 None
 0.96A 1mz9C-1escA:
0.0		 1mz9C-1escA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gr0 INOSITOL-3-PHOSPHATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF01658
(Inos-1-P_synth) 		4 ILE A  20
LEU A  30
VAL A  34
ALA A  40
 None
 0.91A 1mz9C-1gr0A:
0.0		 1mz9C-1gr0A:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h2s SENSORY RHODOPSIN II
TRANSDUCER

(Natronomonas
pharaonis) 		no annotation 4 ILE B  68
LEU B  65
VAL B  61
ALA B  54
 None
 0.97A 1mz9C-1h2sB:
2.6		 1mz9C-1h2sB:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htw HI0065

(Haemophilus
influenzae) 		PF02367
(TsaE) 		4 ILE A 131
LEU A  38
VAL A  36
ALA A  33
 None
 0.84A 1mz9C-1htwA:
undetectable		 1mz9C-1htwA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfi PHOSPHOGLUCOMUTASE 1

(Paramecium
tetraurelia) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 LEU A 415
VAL A 411
ALA A 311
CYH A 307
 None
 0.91A 1mz9C-1kfiA:
undetectable		 1mz9C-1kfiA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mu2 HIV-2 RT

(Human
immunodeficiency
virus 2) 		PF00075
(RNase_H)
PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		4 ILE A 364
LEU A 367
VAL A 371
ALA A 378
 None
 0.72A 1mz9C-1mu2A:
undetectable		 1mz9C-1mu2A:
5.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mu2 HIV-2 RT

(Human
immunodeficiency
virus 2) 		PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		4 ILE B 364
LEU B 367
VAL B 371
ALA B 378
 None
 0.83A 1mz9C-1mu2B:
undetectable		 1mz9C-1mu2B:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oy0 KETOPANTOATE
HYDROXYMETHYLTRANSFE
RASE

(Mycobacterium
tuberculosis) 		PF02548
(Pantoate_transf) 		4 ILE A  79
LEU A  82
VAL A  86
ALA A  93
 None
 0.94A 1mz9C-1oy0A:
undetectable		 1mz9C-1oy0A:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q3k CREATININASE

(Pseudomonas
putida) 		PF02633
(Creatininase) 		4 ILE A 103
LEU A 106
VAL A 111
ALA A  21
 None
 0.98A 1mz9C-1q3kA:
undetectable		 1mz9C-1q3kA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r03 MITOCHONDRIAL
FERRITIN

(Homo sapiens) 		PF00210
(Ferritin) 		4 ILE A 145
LEU A 148
VAL A 152
ALA A 160
 None
 0.78A 1mz9C-1r03A:
undetectable		 1mz9C-1r03A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4n AMYLOID BETA
PRECURSOR
PROTEIN-BINDING
PROTEIN 1

(Homo sapiens) 		PF00899
(ThiF) 		4 ILE A 368
LEU A 365
VAL A 361
ALA A 354
 None
 0.87A 1mz9C-1r4nA:
undetectable		 1mz9C-1r4nA:
6.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r76 PECTATE LYASE

(Niveispirillum
irakense) 		PF09492
(Pec_lyase) 		4 ILE A 179
LEU A 182
VAL A 186
ALA A 190
 None
 0.84A 1mz9C-1r76A:
undetectable		 1mz9C-1r76A:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rzm PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE

(Thermotoga
maritima) 		PF00793
(DAHP_synth_1) 		4 ILE A  83
LEU A  85
VAL A 124
ALA A 114
 None
 0.95A 1mz9C-1rzmA:
undetectable		 1mz9C-1rzmA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s0u TRANSLATION
INITIATION FACTOR 2
GAMMA SUBUNIT

(Methanocaldococcus
jannaschii) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF09173
(eIF2_C) 		4 ILE A 221
LEU A 217
VAL A 170
ALA A 143
 None
 0.91A 1mz9C-1s0uA:
undetectable		 1mz9C-1s0uA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t11 TRIGGER FACTOR

(Vibrio cholerae) 		PF00254
(FKBP_C)
PF05697
(Trigger_N)
PF05698
(Trigger_C) 		4 ILE A  35
LEU A  32
VAL A  28
ALA A  21
 None
 0.90A 1mz9C-1t11A:
undetectable		 1mz9C-1t11A:
7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1taf TFIID TBP ASSOCIATED
FACTOR 62

(Drosophila
melanogaster) 		PF02969
(TAF) 		4 ILE B  43
LEU B  40
VAL B  36
ALA B  29
 None
 0.97A 1mz9C-1tafB:
2.3		 1mz9C-1tafB:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tcd TRIOSEPHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF00121
(TIM) 		4 ILE A 209
LEU A 207
VAL A 163
CYH A 118
 None
 0.98A 1mz9C-1tcdA:
undetectable		 1mz9C-1tcdA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdj BIOSYNTHETIC
THREONINE DEAMINASE

(Escherichia
coli) 		PF00291
(PALP)
PF00585
(Thr_dehydrat_C) 		4 ILE A 395
LEU A 399
VAL A 343
ALA A 377
 None
 0.94A 1mz9C-1tdjA:
undetectable		 1mz9C-1tdjA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tkn AMYLOID BETA A4
PROTEIN

(Homo sapiens) 		PF12925
(APP_E2) 		4 ILE A 537
LEU A 534
VAL A 530
ALA A 524
 None
 0.95A 1mz9C-1tknA:
undetectable		 1mz9C-1tknA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9l GLUTAMATE
DEHYDROGENASE

(Pyrobaculum
islandicum) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ILE A 332
LEU A 333
VAL A 340
ALA A 346
 None
 0.95A 1mz9C-1v9lA:
undetectable		 1mz9C-1v9lA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vc2 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 ILE A  18
LEU A  19
VAL A  26
ALA A  85
 None
 0.91A 1mz9C-1vc2A:
undetectable		 1mz9C-1vc2A:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vdk FUMARATE HYDRATASE
CLASS II

(Thermus
thermophilus) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 ILE A 373
LEU A 376
VAL A 380
ALA A 388
 None
 0.98A 1mz9C-1vdkA:
undetectable		 1mz9C-1vdkA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b9c STRIATED-MUSCLE
ALPHA TROPOMYOSIN

(Rattus
norvegicus) 		PF00261
(Tropomyosin) 		4 ILE A 172
LEU A 169
VAL A 165
ALA A 158
 None
 0.98A 1mz9C-2b9cA:
3.8		 1mz9C-2b9cA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bex RIBONUCLEASE
INHIBITOR

(Homo sapiens) 		PF13516
(LRR_6) 		4 ILE A 262
LEU A 233
VAL A 210
ALA A 184
 None
 0.94A 1mz9C-2bexA:
undetectable		 1mz9C-2bexA:
7.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cit ENDOGLUCANASE H

(Ruminiclostridium
thermocellum) 		PF02156
(Glyco_hydro_26) 		4 ILE A  11
LEU A   9
VAL A 250
ALA A 212
 None
 0.85A 1mz9C-2citA:
undetectable		 1mz9C-2citA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwc 433AA LONG
HYPOTHETICAL
PHOSPHORIBOSYLGLYCIN
AMIDE FORMYL
TRANSFERASE

(Pyrococcus
horikoshii) 		PF02222
(ATP-grasp) 		4 ILE A  86
LEU A  23
VAL A  48
ALA A  52
 None
 0.98A 1mz9C-2dwcA:
undetectable		 1mz9C-2dwcA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f3o PYRUVATE
FORMATE-LYASE 2

(Archaeoglobus
fulgidus) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		4 ILE A 555
LEU A 552
VAL A 548
ALA A 542
 None
 0.88A 1mz9C-2f3oA:
undetectable		 1mz9C-2f3oA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f95 SENSORY RHODOPSIN II
TRANSDUCER

(Natronomonas
pharaonis) 		no annotation 4 ILE B  68
LEU B  65
VAL B  61
ALA B  54
 None
 0.98A 1mz9C-2f95B:
undetectable		 1mz9C-2f95B:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fhg PROTEASOME, BETA
SUBUNIT

(Mycobacterium
tuberculosis) 		no annotation 4 ILE H 380
LEU H 383
VAL H 387
ALA H 393
 None
 0.82A 1mz9C-2fhgH:
undetectable		 1mz9C-2fhgH:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gdu SUCROSE
PHOSPHORYLASE

(Bifidobacterium
adolescentis) 		PF00128
(Alpha-amylase)
PF09244
(DUF1964) 		4 ILE A 229
LEU A 227
VAL A 186
ALA A  72
 None
 0.88A 1mz9C-2gduA:
undetectable		 1mz9C-2gduA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gq3 MALATE SYNTHASE G

(Mycobacterium
tuberculosis) 		PF01274
(Malate_synthase) 		4 ILE A 581
LEU A 579
VAL A 440
ALA A 444
 None
 0.92A 1mz9C-2gq3A:
undetectable		 1mz9C-2gq3A:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		4 ILE A 647
LEU A 644
VAL A 640
ALA A 633
 None
 0.97A 1mz9C-2h4tA:
undetectable		 1mz9C-2h4tA:
5.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jay PROTEASOME

(Mycobacterium
tuberculosis) 		PF00227
(Proteasome) 		4 ILE A 137
LEU A 140
VAL A 144
ALA A 150
 None
 0.73A 1mz9C-2jayA:
undetectable		 1mz9C-2jayA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ji4 PHOSPHORIBOSYL
PYROPHOSPHATE
SYNTHETASE-ASSOCIATE
D PROTEIN 2

(Homo sapiens) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		4 ILE A  86
LEU A  89
VAL A  93
ALA A 101
 None
 0.58A 1mz9C-2ji4A:
undetectable		 1mz9C-2ji4A:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k9a ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
2-BINDING PROTEIN

(Homo sapiens) 		PF11527
(ARL2_Bind_BART) 		4 ILE A  31
LEU A  28
VAL A  24
ALA A  16
 None
 0.77A 1mz9C-2k9aA:
undetectable		 1mz9C-2k9aA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ntb PECTINESTERASE A

(Dickeya
dadantii) 		PF01095
(Pectinesterase) 		4 ILE A 201
LEU A 180
VAL A 159
ALA A 119
 None
 0.88A 1mz9C-2ntbA:
undetectable		 1mz9C-2ntbA:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pn1 CARBAMOYLPHOSPHATE
SYNTHASE LARGE
SUBUNIT

(Exiguobacterium
sibiricum) 		PF02655
(ATP-grasp_3) 		4 ILE A   8
LEU A  76
ALA A 107
CYH A 108
 None
 0.87A 1mz9C-2pn1A:
undetectable		 1mz9C-2pn1A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q6z UROPORPHYRINOGEN
DECARBOXYLASE

(Homo sapiens) 		PF01208
(URO-D) 		4 LEU A 131
VAL A 134
ALA A  64
CYH A  65
 None
 0.94A 1mz9C-2q6zA:
undetectable		 1mz9C-2q6zA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v55 RHO-ASSOCIATED
PROTEIN KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 ILE A 189
LEU A 186
VAL A 182
ALA A 175
 None
 0.70A 1mz9C-2v55A:
undetectable		 1mz9C-2v55A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xal INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Arabidopsis
thaliana) 		PF06090
(Ins_P5_2-kin) 		4 ILE A 307
LEU A 304
VAL A 300
ALA A 294
 None
 0.83A 1mz9C-2xalA:
undetectable		 1mz9C-2xalA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3adc L-SERYL-TRNA(SEC)
KINASE

(Methanocaldococcus
jannaschii) 		PF08433
(KTI12) 		4 ILE A  23
LEU A  24
VAL A  31
ALA A  65
 None
 0.96A 1mz9C-3adcA:
undetectable		 1mz9C-3adcA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3afb PUTATIVE CHITINASE

(Pyrococcus
furiosus) 		no annotation 4 ILE A 613
LEU A 610
VAL A 606
ALA A 599
 None
 0.73A 1mz9C-3afbA:
undetectable		 1mz9C-3afbA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3auf GLYCINAMIDE
RIBONUCLEOTIDE
TRANSFORMYLASE 1

(Symbiobacterium
toebii) 		PF00551
(Formyl_trans_N) 		5 ILE A 105
LEU A 106
VAL A 137
ALA A 153
CYH A 135
 None
 1.41A 1mz9C-3aufA:
undetectable		 1mz9C-3aufA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c2g SYS-1 PROTEIN

(Caenorhabditis
elegans) 		no annotation 5 ILE A 618
LEU A 619
VAL A 661
ALA A 717
CYH A 715
 None
 1.10A 1mz9C-3c2gA:
undetectable		 1mz9C-3c2gA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cje OSMC-LIKE PROTEIN

(Jannaschia sp.
CCS1) 		PF02566
(OsmC) 		4 ILE A  66
LEU A  69
VAL A  73
ALA A 136
 None
 0.87A 1mz9C-3cjeA:
undetectable		 1mz9C-3cjeA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmn PUTATIVE HYDROLASE

(Chloroflexus
aurantiacus) 		PF10103
(Zincin_2) 		4 ILE A 293
LEU A 292
VAL A 353
ALA A 359
 None
 0.75A 1mz9C-3cmnA:
undetectable		 1mz9C-3cmnA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cpg UNCHARACTERIZED
PROTEIN

(Bifidobacterium
adolescentis) 		PF01168
(Ala_racemase_N) 		4 ILE A  36
LEU A  33
VAL A  29
ALA A  22
 None
 0.97A 1mz9C-3cpgA:
undetectable		 1mz9C-3cpgA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d0c DIHYDRODIPICOLINATE
SYNTHASE

(Oceanobacillus
iheyensis) 		PF00701
(DHDPS) 		4 ILE A  28
LEU A  33
VAL A  72
ALA A  80
 None
 0.94A 1mz9C-3d0cA:
undetectable		 1mz9C-3d0cA:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d8l ORF12

(Lactococcus
virus P2) 		no annotation 4 ILE A  37
LEU A  40
VAL A  44
ALA A  51
 None
 0.96A 1mz9C-3d8lA:
undetectable		 1mz9C-3d8lA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3edv SPECTRIN BETA CHAIN,
BRAIN 1

(Homo sapiens) 		PF00435
(Spectrin) 		4 ILE A1853
LEU A1856
VAL A1860
ALA A1867
 None
 0.82A 1mz9C-3edvA:
undetectable		 1mz9C-3edvA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ehk PRUNIN

(Prunus dulcis) 		PF00190
(Cupin_1) 		4 ILE A 438
LEU A 439
VAL A 428
ALA A 461
 None
 0.97A 1mz9C-3ehkA:
undetectable		 1mz9C-3ehkA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ek5 URIDYLATE KINASE

(Xanthomonas
campestris) 		PF00696
(AA_kinase) 		4 ILE A  31
LEU A  34
VAL A  38
ALA A  46
 None
 0.64A 1mz9C-3ek5A:
undetectable		 1mz9C-3ek5A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f3z CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase) 		4 ILE A 168
LEU A 167
VAL A 132
ALA A 276
 DRK  A   1 ( 4.2A)
None
None
None
 0.95A 1mz9C-3f3zA:
undetectable		 1mz9C-3f3zA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7p NITROGEN FIXATION
PROTEIN

(Acidithiobacillus
ferrooxidans) 		PF03270
(DUF269) 		4 ILE A 146
LEU A 143
VAL A 139
ALA A 132
 None
 0.80A 1mz9C-3g7pA:
undetectable		 1mz9C-3g7pA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h3j L-LACTATE
DEHYDROGENASE 1

(Staphylococcus
aureus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A 243
LEU A 240
VAL A 236
ALA A 231
 None
None
NAD  A 500 (-4.2A)
NAD  A 500 ( 4.5A)
 0.81A 1mz9C-3h3jA:
undetectable		 1mz9C-3h3jA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvy CYSTATHIONINE
BETA-LYASE FAMILY
PROTEIN, YNBB
B.SUBTILIS ORTHOLOG

(Clostridium
acetobutylicum) 		PF06838
(Met_gamma_lyase) 		4 ILE A 345
LEU A 344
ALA A 311
CYH A 310
 None
 0.67A 1mz9C-3hvyA:
undetectable		 1mz9C-3hvyA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcl SPIKE GLYCOPROTEIN

(Murine
coronavirus) 		PF01601
(Corona_S2)
PF09408
(Spike_rec_bind)
PF16451
(Spike_NTD) 		4 ILE A 764
LEU A1110
VAL A1103
ALA A 933
 None
 0.79A 1mz9C-3jclA:
undetectable		 1mz9C-3jclA:
3.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9d ALDEHYDE
DEHYDROGENASE

(Listeria
monocytogenes) 		PF00171
(Aldedh) 		4 ILE A 195
VAL A 217
ALA A 252
CYH A 251
 None
 0.86A 1mz9C-3k9dA:
undetectable		 1mz9C-3k9dA:
6.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l2z BIRA BIFUNCTIONAL
PROTEIN

(Mycobacterium
tuberculosis) 		PF02237
(BPL_C)
PF03099
(BPL_LplA_LipB) 		4 ILE A 186
LEU A 190
VAL A 155
ALA A 144
 None
 0.91A 1mz9C-3l2zA:
undetectable		 1mz9C-3l2zA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lki FRUCTOKINASE

(Xylella
fastidiosa) 		PF00294
(PfkB) 		4 ILE A 224
LEU A 227
VAL A 202
ALA A 143
 None
 0.96A 1mz9C-3lkiA:
undetectable		 1mz9C-3lkiA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pg8 PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE

(Thermotoga
maritima) 		PF00793
(DAHP_synth_1) 		4 ILE A  83
LEU A  85
VAL A 124
ALA A 114
 None
 0.96A 1mz9C-3pg8A:
undetectable		 1mz9C-3pg8A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pqd L-LACTATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A 243
LEU A 240
VAL A 236
ALA A 231
 None
 0.84A 1mz9C-3pqdA:
undetectable		 1mz9C-3pqdA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1i DOUBLE-STRAND BREAK
REPAIR PROTEIN
MRE11A

(Homo sapiens) 		PF00149
(Metallophos)
PF04152
(Mre11_DNA_bind) 		4 ILE A 395
LEU A 365
VAL A 367
ALA A 315
 None
 0.94A 1mz9C-3t1iA:
undetectable		 1mz9C-3t1iA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tv2 FUMARATE HYDRATASE,
CLASS II

(Burkholderia
pseudomallei) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 ILE A 431
LEU A 428
VAL A 424
ALA A 417
 None
 0.90A 1mz9C-3tv2A:
undetectable		 1mz9C-3tv2A:
8.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v2p CARTILAGE
OLIGOMERIZATION
MATRIX PROTEIN
(COILED-COIL DOMAIN)

(Mus musculus) 		PF11598
(COMP) 		4 ILE A  58
LEU A  61
VAL A  65
ALA A  70
 None
 0.23A 1mz9C-3v2pA:
undetectable		 1mz9C-3v2pA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wnw FERRITIN HEAVY CHAIN

(Mus musculus) 		PF00210
(Ferritin) 		4 ILE A 145
LEU A 148
VAL A 152
ALA A 160
 None
 0.79A 1mz9C-3wnwA:
undetectable		 1mz9C-3wnwA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ac1 ENDO-N-ACETYL-BETA-D
-GLUCOSAMINIDASE

(Trichoderma
reesei) 		PF00704
(Glyco_hydro_18) 		4 ILE X 234
LEU X 239
VAL X 279
ALA X  36
 None
None
None
ACT  X1290 (-4.4A)
 0.79A 1mz9C-4ac1X:
undetectable		 1mz9C-4ac1X:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4av6 K(+)-STIMULATED
PYROPHOSPHATE-ENERGI
ZED SODIUM PUMP

(Thermotoga
maritima) 		PF03030
(H_PPase) 		4 ILE A  70
LEU A  67
VAL A  63
ALA A  56
 None
 0.98A 1mz9C-4av6A:
undetectable		 1mz9C-4av6A:
4.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg5 BBA65

(Borreliella
burgdorferi) 		PF05714
(Borrelia_lipo_1) 		4 ILE A 100
LEU A 103
VAL A 107
ALA A 116
 None
 0.85A 1mz9C-4bg5A:
undetectable		 1mz9C-4bg5A:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7v TRANSKETOLASE

(Lactobacillus
salivarius) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 ILE A 528
LEU A 526
VAL A 562
ALA A 614
 None
 0.98A 1mz9C-4c7vA:
undetectable		 1mz9C-4c7vA:
5.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dmm 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE

(Synechococcus
elongatus) 		PF13561
(adh_short_C2) 		4 ILE A 208
LEU A 246
VAL A 146
ALA A 163
 None
 0.95A 1mz9C-4dmmA:
undetectable		 1mz9C-4dmmA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyx FERRITIN HEAVY CHAIN

(Homo sapiens) 		PF00210
(Ferritin) 		4 ILE A 145
LEU A 148
VAL A 152
ALA A 160
 None
 0.84A 1mz9C-4dyxA:
undetectable		 1mz9C-4dyxA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e0b MALATE DEHYDROGENASE

(Vibrio
vulnificus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ILE A  49
LEU A  46
VAL A  42
ALA A  36
 None
 0.98A 1mz9C-4e0bA:
undetectable		 1mz9C-4e0bA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6e CELL DIVISION
PROTEIN FTSZ

(Thermobifida
fusca) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 ILE A 148
LEU A 151
VAL A 155
ALA A 123
 None
 0.72A 1mz9C-4e6eA:
undetectable		 1mz9C-4e6eA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ebj AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Pseudomonas
aeruginosa) 		PF01909
(NTP_transf_2) 		4 ILE A 165
LEU A 162
VAL A 158
ALA A 151
 None
 0.81A 1mz9C-4ebjA:
undetectable		 1mz9C-4ebjA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gji L-RHAMNOSE ISOMERASE

(Pseudomonas
stutzeri) 		no annotation 4 ILE A 165
LEU A 162
VAL A 158
ALA A 151
 None
 0.73A 1mz9C-4gjiA:
undetectable		 1mz9C-4gjiA:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gs1 DYP-TYPE PEROXIDASE

(Thermobifida
cellulosilytica) 		PF04261
(Dyp_perox) 		4 ILE A  87
LEU A 184
VAL A 140
ALA A  68
 None
 0.88A 1mz9C-4gs1A:
undetectable		 1mz9C-4gs1A:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gyc SENSORY RHODOPSIN II
TRANSDUCER

(Natronomonas
pharaonis) 		no annotation 4 ILE B  68
LEU B  65
VAL B  61
ALA B  54
 None
 0.96A 1mz9C-4gycB:
undetectable		 1mz9C-4gycB:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyq PHOSPHOLIPASE A1

(Streptomyces
albidoflavus) 		PF13472
(Lipase_GDSL_2) 		4 ILE A 189
LEU A 140
VAL A 138
ALA A 135
 None
 0.90A 1mz9C-4hyqA:
undetectable		 1mz9C-4hyqA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i59 CYCLOHEXYLAMINE
OXIDASE

(Microbacterium
oxydans) 		PF01593
(Amino_oxidase) 		4 ILE A  97
LEU A  96
VAL A 464
ALA A 290
 None
 0.99A 1mz9C-4i59A:
undetectable		 1mz9C-4i59A:
6.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN

(Viscum album) 		PF00161
(RIP) 		4 ILE A 132
LEU A 135
VAL A 139
ALA A  82
 None
 0.96A 1mz9C-4jkxA:
undetectable		 1mz9C-4jkxA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kng LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 5

(Homo sapiens) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8) 		4 ILE A 198
LEU A 174
VAL A 153
CYH A 157
 None
 0.79A 1mz9C-4kngA:
undetectable		 1mz9C-4kngA:
7.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpg MEMBRANE-ANCHORED
MYCOSIN MYCP1

(Mycolicibacterium
smegmatis) 		PF00082
(Peptidase_S8) 		4 ILE A 181
LEU A 184
VAL A 188
ALA A 196
 None
 0.67A 1mz9C-4kpgA:
undetectable		 1mz9C-4kpgA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l1k D-ALANINE--D-ALANINE
LIGASE

(Xanthomonas
oryzae) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ILE A 175
LEU A 174
VAL A 220
ALA A 187
 None
 0.83A 1mz9C-4l1kA:
undetectable		 1mz9C-4l1kA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m0x CHLOROMUCONATE
CYCLOISOMERASE

(Rhodococcus
opacus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 187
LEU A 184
VAL A 180
ALA A 173
 None
 0.92A 1mz9C-4m0xA:
undetectable		 1mz9C-4m0xA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1z MEMBRANE-ANCHORED
MYCOSIN MYCP1

(Mycolicibacterium
smegmatis) 		PF00082
(Peptidase_S8) 		4 ILE A 181
LEU A 184
VAL A 188
ALA A 196
 None
 0.87A 1mz9C-4m1zA:
undetectable		 1mz9C-4m1zA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m7a U6 SNRNA-ASSOCIATED
SM-LIKE PROTEIN LSM7

(Saccharomyces
cerevisiae) 		PF01423
(LSM) 		4 ILE F  98
LEU F  42
VAL F  40
ALA F 105
 None
 0.79A 1mz9C-4m7aF:
undetectable		 1mz9C-4m7aF:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n18 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN

(Klebsiella
pneumoniae) 		PF02826
(2-Hacid_dh_C) 		4 ILE A 270
LEU A 262
VAL A 234
ALA A 208
 None
 0.98A 1mz9C-4n18A:
undetectable		 1mz9C-4n18A:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6

(Oryza sativa) 		PF00481
(PP2C) 		4 ILE B 450
LEU B 388
VAL B 382
CYH B 380
 None
 0.99A 1mz9C-4oicB:
undetectable		 1mz9C-4oicB:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A

(Pseudomonas
mendocina) 		PF02332
(Phenol_Hydrox) 		4 ILE A 246
LEU A 242
VAL A 258
ALA A 265
 None
 0.90A 1mz9C-4p1cA:
undetectable		 1mz9C-4p1cA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pzv 2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE/DI
HYDROPTEROATE
SYNTHASE

(Francisella
tularensis) 		PF00809
(Pterin_bind)
PF01288
(HPPK) 		4 ILE A 201
LEU A 197
VAL A 176
ALA A 212
 None
 0.97A 1mz9C-4pzvA:
undetectable		 1mz9C-4pzvA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4y COXSACKIEVIRUS
CAPSID PROTEIN VP2
COXSACKIEVIRUS
CAPSID PROTEIN VP3

(Enterovirus C) 		PF00073
(Rhv) 		4 ILE 3 102
LEU 3  46
VAL 2 191
ALA 2 126
 None
 0.97A 1mz9C-4q4y3:
undetectable		 1mz9C-4q4y3:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r10 PROTEIN HUMPBACK-2

(Caenorhabditis
elegans) 		PF00514
(Arm) 		4 ILE A 333
LEU A 336
ALA A 420
CYH A 418
 None
 0.82A 1mz9C-4r10A:
undetectable		 1mz9C-4r10A:
7.24