SIMILAR PATTERNS OF AMINO ACIDS FOR 1MUI_B_AB1B100_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1b4e	PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE) (Escherichia coli)	PF00490 (ALAD)	5	GLY A 305 ALA A 306 ASP A 307 ILE A 255 ILE A 301	None	0.95A	1muiA-1b4eA: undetectable	1muiA-1b4eA: 13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1bu8	PROTEIN (PANCREATIC LIPASE RELATED PROTEIN 2) (Rattus norvegicus)	PF00151 (Lipase) PF01477 (PLAT)	5	ALA A 161 VAL A 124 GLY A 150 ILE A 149 ILE A 128	None	0.94A	1muiA-1bu8A: undetectable	1muiA-1bu8A: 14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1czi	CHYMOSIN (Bos taurus)	PF00026 (Asp)	5	ASP E 215 GLY E 217 VAL E 222 GLY E 76 ILE E 300	None	0.84A	1muiA-1cziE: 6.8	1muiA-1cziE: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ea6	PMS1 PROTEIN HOMOLOG 2 (Homo sapiens)	PF01119 (DNA_mis_repair) PF13589 (HATPase_c_3)	5	GLY A 50 ALA A 51 ASP A 70 VAL A 200 ILE A 198	None None ADP A1366 (-3.4A) None None	0.97A	1muiA-1ea6A: undetectable	1muiA-1ea6A: 14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1fob	BETA-1,4-GALACTANASE (Aspergillus aculeatus)	PF07745 (Glyco_hydro_53)	6	GLY A 40 ALA A 39 ASP A 38 VAL A 324 ILE A 44 ILE A 328	None	1.11A	1muiA-1fobA: undetectable	1muiA-1fobA: 14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1hrd	GLUTAMATE DEHYDROGENASE ([Clostridium] symbiosum)	PF00208 (ELFV_dehydrog) PF02812 (ELFV_dehydrog_N)	6	GLY A 300 ALA A 296 ASP A 297 ASP A 294 VAL A 292 ILE A 266	None	1.46A	1muiA-1hrdA: undetectable	1muiA-1hrdA: 11.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1hvc	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	6	ASP A 25 ALA A 28 ASP A 29 GLY A 49 ILE A 50 ILE A 84	A79 A 800 (-2.7A) A79 A 800 (-3.1A) A79 A 800 (-2.8A) A79 A 800 ( 3.7A) A79 A 800 (-3.8A) A79 A 800 (-3.6A)	1.22A	1muiA-1hvcA: 13.7	1muiA-1hvcA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1hvc	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	10	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 VAL A 32 GLY A 49 ILE A 50 PRO A 81 ILE A 84	A79 A 800 (-2.7A) A79 A 800 (-3.0A) A79 A 800 (-3.1A) A79 A 800 (-2.8A) A79 A 800 ( 4.9A) A79 A 800 ( 4.4A) A79 A 800 ( 3.7A) A79 A 800 (-3.8A) A79 A 800 ( 3.9A) A79 A 800 (-3.6A)	0.56A	1muiA-1hvcA: 13.7	1muiA-1hvcA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1hvc	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	10	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 VAL A 32 GLY A 49 ILE A 50 PRO A 81 ILE A 84	A79 A 800 (-2.8A) A79 A 800 (-3.0A) A79 A 800 (-3.2A) A79 A 800 (-2.7A) A79 A 800 ( 4.7A) A79 A 800 ( 4.3A) A79 A 800 (-3.4A) A79 A 800 ( 4.0A) A79 A 800 ( 3.4A) A79 A 800 (-3.8A)	0.46A	1muiA-1hvcA: 13.7	1muiA-1hvcA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1hvc	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	7	ASP A 25 GLY A 27 ALA A 28 ASP A 29 GLY A 48 PRO A 81 ILE A 84	A79 A 800 (-2.8A) A79 A 800 (-3.0A) A79 A 800 (-3.2A) A79 A 800 (-2.7A) A79 A 800 (-4.1A) A79 A 800 ( 3.4A) A79 A 800 (-3.8A)	0.89A	1muiA-1hvcA: 13.7	1muiA-1hvcA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1hvc	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	7	ASP A 25 GLY A 27 ALA A 28 ASP A 29 VAL A 32 GLY A 48 ILE A 84	A79 A 800 (-2.7A) A79 A 800 (-3.0A) A79 A 800 (-3.1A) A79 A 800 (-2.8A) A79 A 800 ( 4.4A) A79 A 800 (-3.6A) A79 A 800 (-3.6A)	0.81A	1muiA-1hvcA: 13.7	1muiA-1hvcA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1kae	HISTIDINOL DEHYDROGENASE (Escherichia coli)	PF00815 (Histidinol_dh)	5	GLY A 227 ALA A 228 ASP A 204 GLY A 196 ILE A 206	None	0.87A	1muiA-1kaeA: undetectable	1muiA-1kaeA: 13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1l5j	ACONITATE HYDRATASE 2 (Escherichia coli)	PF00330 (Aconitase) PF06434 (Aconitase_2_N) PF11791 (Aconitase_B_N)	5	GLY A 721 ALA A 720 GLY A 715 ILE A 714 ILE A 707	None	0.95A	1muiA-1l5jA: undetectable	1muiA-1l5jA: 9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1lk5	D-RIBOSE-5-PHOSPHATE ISOMERASE (Pyrococcus horikoshii)	PF06026 (Rib_5-P_isom_A)	5	GLY A 101 ALA A 102 GLY A 207 ILE A 97 ILE A 179	CL A1001 (-3.4A) None None None None	0.90A	1muiA-1lk5A: undetectable	1muiA-1lk5A: 18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1m0s	RIBOSE-5-PHOSPHATE ISOMERASE A (Haemophilus influenzae)	PF06026 (Rib_5-P_isom_A)	5	GLY A 97 ALA A 98 GLY A 197 ILE A 93 ILE A 169	CIT A 501 (-3.1A) None None None None	0.98A	1muiA-1m0sA: undetectable	1muiA-1m0sA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1orf	GRANZYME A (Homo sapiens)	PF00089 (Trypsin)	5	GLY A 44 ALA A 45 GLY A 211 ILE A 229 ILE A 47	None	0.96A	1muiA-1orfA: undetectable	1muiA-1orfA: 16.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1q9p	HIV-1 PROTEASE (Homo sapiens)	PF00077 (RVP)	8	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 VAL A 32 PRO A 81 ILE A 84	None	0.79A	1muiA-1q9pA: 10.4	1muiA-1q9pA: 94.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1siv	SIV PROTEASE (Simian immunodeficiency virus)	PF00077 (RVP)	6	ASP A 25 ALA A 28 ASP A 29 GLY A 49 PRO A 81 ILE A 84	None	1.36A	1muiA-1sivA: 18.2	1muiA-1sivA: 50.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1siv	SIV PROTEASE (Simian immunodeficiency virus)	PF00077 (RVP)	9	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 GLY A 49 ILE A 50 PRO A 81 ILE A 84	None	0.52A	1muiA-1sivA: 18.2	1muiA-1sivA: 50.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1siv	SIV PROTEASE (Simian immunodeficiency virus)	PF00077 (RVP)	7	ASP A 25 GLY A 27 ALA A 28 ASP A 29 GLY A 48 PRO A 81 ILE A 84	None	0.85A	1muiA-1sivA: 18.2	1muiA-1sivA: 50.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1v43	SUGAR-BINDING TRANSPORT ATP-BINDING PROTEIN (Pyrococcus horikoshii)	PF00005 (ABC_tran) PF08402 (TOBE_2)	5	ALA A 206 ASP A 202 VAL A 215 GLY A 244 ILE A 213	None	0.89A	1muiA-1v43A: undetectable	1muiA-1v43A: 14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1xi3	THIAMINE PHOSPHATE PYROPHOSPHORYLASE (Pyrococcus furiosus)	PF02581 (TMP-TENI)	5	GLY A 127 ALA A 126 VAL A 150 GLY A 178 ILE A 179	None	0.93A	1muiA-1xi3A: undetectable	1muiA-1xi3A: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1xtz	RIBOSE-5-PHOSPHATE ISOMERASE (Saccharomyces cerevisiae)	PF06026 (Rib_5-P_isom_A)	5	GLY A 123 ALA A 124 GLY A 235 ILE A 119 ILE A 207	None	0.98A	1muiA-1xtzA: undetectable	1muiA-1xtzA: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1yg0	COP ASSOCIATED PROTEIN (Helicobacter pylori)	PF00403 (HMA)	5	GLY A 62 ALA A 61 ASP A 60 VAL A 23 ILE A 19	None	0.93A	1muiA-1yg0A: undetectable	1muiA-1yg0A: 19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2bc0	NADH OXIDASE (Streptococcus pyogenes)	PF02852 (Pyr_redox_dim) PF07992 (Pyr_redox_2)	5	GLY A 453 ALA A 454 ASP A 456 ILE A 387 ILE A 426	None	0.77A	1muiA-2bc0A: undetectable	1muiA-2bc0A: 12.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2fmb	EQUINE INFECTIOUS ANEMIA VIRUS PROTEASE (Equine infectious anemia virus)	PF00077 (RVP)	7	ASP A 25 GLY A 27 ALA A 28 ASP A 29 VAL A 32 GLY A 54 ILE A 89	LP1 A 201 (-2.3A) LP1 A 201 (-3.8A) LP1 A 201 (-3.5A) LP1 A 201 (-3.6A) None LP1 A 201 (-3.6A) LP1 A 201 (-4.2A)	0.84A	1muiA-2fmbA: 15.3	1muiA-2fmbA: 30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2fmb	EQUINE INFECTIOUS ANEMIA VIRUS PROTEASE (Equine infectious anemia virus)	PF00077 (RVP)	8	ASP A 25 GLY A 27 ALA A 28 ASP A 29 VAL A 32 GLY A 55 PRO A 86 ILE A 89	LP1 A 201 (-2.3A) LP1 A 201 (-3.8A) LP1 A 201 (-3.5A) LP1 A 201 (-3.6A) None LP1 A 201 (-3.4A) LP1 A 201 (-3.9A) LP1 A 201 (-4.2A)	0.52A	1muiA-2fmbA: 15.3	1muiA-2fmbA: 30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2g4r	MOLYBDOPTERIN BIOSYNTHESIS MOG PROTEIN (Mycobacterium tuberculosis)	PF00994 (MoCF_biosynth)	5	GLY A 115 ASP A 97 GLY A 118 ILE A 125 ILE A 99	None TRS A 301 (-2.8A) None None None	0.88A	1muiA-2g4rA: undetectable	1muiA-2g4rA: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2isq	CYSTEINE SYNTHASE (Arabidopsis thaliana)	PF00291 (PALP)	5	GLY A 190 ALA A 189 GLY A 183 ILE A 180 PRO A 296	None None PLP A 400 (-3.4A) PLP A 400 (-4.9A) PLP A 400 (-4.0A)	0.81A	1muiA-2isqA: undetectable	1muiA-2isqA: 15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2it1	362AA LONG HYPOTHETICAL MALTOSE/MALTODEXTRIN TRANSPORT ATP-BINDING PROTEIN (Pyrococcus horikoshii)	PF00005 (ABC_tran)	5	ALA A 197 ASP A 193 VAL A 206 GLY A 235 ILE A 204	None	0.93A	1muiA-2it1A: undetectable	1muiA-2it1A: 13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2odp	COMPLEMENT C2 (Homo sapiens)	PF00089 (Trypsin) PF00092 (VWA)	5	GLY A 474 ALA A 475 GLY A 675 ILE A 710 ILE A 477	None	0.96A	1muiA-2odpA: undetectable	1muiA-2odpA: 10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2p3e	DIAMINOPIMELATE DECARBOXYLASE (Aquifex aeolicus)	PF00278 (Orn_DAP_Arg_deC) PF02784 (Orn_Arg_deC_N)	5	ALA A 355 VAL A 371 GLY A 345 ILE A 308 ILE A 328	None	0.84A	1muiA-2p3eA: undetectable	1muiA-2p3eA: 13.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2rkf	PROTEASE RETROPEPSIN (Human immunodeficiency virus 1)	PF00077 (RVP)	6	ASP A 25 ALA A 28 ASP A 29 GLY A 49 PRO A 81 ILE A 84	AB1 A 501 (-2.4A) AB1 A 501 (-3.5A) AB1 A 501 ( 3.3A) AB1 A 501 (-3.5A) AB1 A 501 (-4.2A) AB1 A 501 ( 4.2A)	1.42A	1muiA-2rkfA: 20.7	1muiA-2rkfA: 87.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2rkf	PROTEASE RETROPEPSIN (Human immunodeficiency virus 1)	PF00077 (RVP)	9	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 GLY A 49 ILE A 50 PRO A 81 ILE A 84	AB1 A 501 (-2.4A) AB1 A 501 (-3.9A) AB1 A 501 (-3.5A) AB1 A 501 ( 3.3A) AB1 A 501 (-3.8A) AB1 A 501 (-3.5A) AB1 A 501 (-3.8A) AB1 A 501 (-4.2A) AB1 A 501 ( 4.2A)	0.45A	1muiA-2rkfA: 20.7	1muiA-2rkfA: 87.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2rkf	PROTEASE RETROPEPSIN (Human immunodeficiency virus 1)	PF00077 (RVP)	6	GLY A 27 ALA A 28 ASP A 29 GLY A 48 PRO A 81 ILE A 84	AB1 A 501 (-3.9A) AB1 A 501 (-3.5A) AB1 A 501 ( 3.3A) AB1 A 501 (-4.2A) AB1 A 501 (-4.2A) AB1 A 501 ( 4.2A)	0.80A	1muiA-2rkfA: 20.7	1muiA-2rkfA: 87.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2rsp	RSV PROTEASE (Rous sarcoma virus)	PF00077 (RVP)	5	ASP A 37 GLY A 39 ALA A 40 ASP A 41 ILE A 108	None	0.32A	1muiA-2rspA: 13.0	1muiA-2rspA: 32.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2w45	ALKALINE EXONUCLEASE (Human gammaherpesvirus 4)	PF01771 (Herpes_alk_exo)	5	GLY A 442 ALA A 441 GLY A 461 PRO A 42 ILE A 197	None	0.98A	1muiA-2w45A: undetectable	1muiA-2w45A: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2w58	PRIMOSOME COMPONENT (HELICASE LOADER) (Geobacillus kaustophilus)	PF01695 (IstB_IS21)	5	GLY A 232 ASP A 230 ASP A 229 GLY A 168 PRO A 300	None None MG A1311 ( 3.9A) None None	0.89A	1muiA-2w58A: undetectable	1muiA-2w58A: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3a0f	XYLOGLUCANASE (Geotrichum sp. M128)	no annotation	5	GLY A 119 ALA A 120 ASP A 34 GLY A 127 ILE A 177	None	0.96A	1muiA-3a0fA: undetectable	1muiA-3a0fA: 8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3b8b	CYSQ, SULFITE SYNTHESIS PATHWAY PROTEIN (Bacteroides thetaiotaomicron)	PF00459 (Inositol_P)	6	ALA A 6 ASP A 5 VAL A 112 GLY A 11 ILE A 14 ILE A 100	None	1.42A	1muiA-3b8bA: undetectable	1muiA-3b8bA: 16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3g1u	ADENOSYLHOMOCYSTEINA SE (Leishmania major)	PF00670 (AdoHcyase_NAD) PF05221 (AdoHcyase)	5	GLY A 383 ALA A 386 VAL A 388 GLY A 151 ILE A 149	None	0.98A	1muiA-3g1uA: undetectable	1muiA-3g1uA: 14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3g7r	PUTATIVE TRANSCRIPTIONAL REGULATOR (Streptomyces coelicolor)	PF00440 (TetR_N)	5	GLY A 166 ALA A 167 VAL A 99 GLY A 186 ILE A 98	None None None None EDO A 960 ( 4.8A)	0.96A	1muiA-3g7rA: undetectable	1muiA-3g7rA: 18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3gve	YFKN PROTEIN (Bacillus subtilis)	PF00149 (Metallophos)	5	GLY A 121 ALA A 122 ASP A 123 ILE A 89 ILE A 126	None	0.76A	1muiA-3gveA: undetectable	1muiA-3gveA: 14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3i5g	MYOSIN HEAVY CHAIN ISOFORM A (Doryteuthis pealeii)	PF00063 (Myosin_head) PF00612 (IQ) PF02736 (Myosin_N)	6	GLY A 264 ALA A 265 ASP A 266 GLY A 460 ILE A 459 ILE A 224	None	1.03A	1muiA-3i5gA: undetectable	1muiA-3i5gA: 8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ifu	NON-STRUCTURAL PROTEIN (Porcine reproductive and respiratory syndrome virus)	PF05410 (Peptidase_C31)	5	GLY A 154 ALA A 155 VAL A 158 PRO A 134 ILE A 131	None	0.96A	1muiA-3ifuA: undetectable	1muiA-3ifuA: 23.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3mws	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	6	ASP A 25 ALA A 28 ASP A 29 GLY A 49 PRO A 81 ILE A 84	None	1.47A	1muiA-3mwsA: 19.3	1muiA-3mwsA: 78.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3mws	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	9	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 VAL A 32 GLY A 48 PRO A 81 ILE A 84	None	0.84A	1muiA-3mwsA: 19.3	1muiA-3mwsA: 78.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3mws	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	10	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 VAL A 32 GLY A 49 ILE A 50 PRO A 81 ILE A 84	None	0.64A	1muiA-3mwsA: 19.3	1muiA-3mwsA: 78.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3pv2	DEGQ (Legionella fallonii)	PF13180 (PDZ_2) PF13365 (Trypsin_2)	5	GLY A 287 ALA A 286 VAL A 321 GLY A 249 ILE A 323	None	0.88A	1muiA-3pv2A: undetectable	1muiA-3pv2A: 12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3rmg	OCTAPRENYL-DIPHOSPHA TE SYNTHASE (Bacteroides thetaiotaomicron)	PF00348 (polyprenyl_synt)	5	ASP A 212 ASP A 213 GLY A 205 ILE A 204 ILE A 289	None	0.96A	1muiA-3rmgA: undetectable	1muiA-3rmgA: 12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3slz	GAG-PRO-POL POLYPROTEIN (Murine leukemia virus)	PF00077 (RVP)	5	ASP A 32 GLY A 34 ALA A 35 VAL A 39 GLY A 56	3TL A 126 (-2.4A) 3TL A 126 (-3.1A) 3TL A 126 ( 4.0A) None 3TL A 126 (-3.4A)	0.56A	1muiA-3slzA: 11.2	1muiA-3slzA: 27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3slz	GAG-PRO-POL POLYPROTEIN (Murine leukemia virus)	PF00077 (RVP)	5	ASP A 32 GLY A 34 ALA A 35 VAL A 39 PRO A 89	3TL A 126 (-2.4A) 3TL A 126 (-3.1A) 3TL A 126 ( 4.0A) None 3TL A 126 (-4.0A)	0.67A	1muiA-3slzA: 11.2	1muiA-3slzA: 27.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3t3c	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	9	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 VAL A 32 GLY A 49 ILE A 50 PRO A 81	017 A 201 (-2.6A) 017 A 201 (-3.4A) 017 A 201 (-3.5A) 017 A 201 (-3.5A) 017 A 201 (-4.2A) None 017 A 201 (-4.0A) 017 A 201 (-3.3A) None	0.79A	1muiA-3t3cA: 18.2	1muiA-3t3cA: 77.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ttp	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	6	ASP A 25 ALA A 28 ASP A 29 GLY A 49 PRO A 81 ILE A 84	017 A 201 (-2.6A) 017 A 201 (-3.4A) 017 A 201 (-3.3A) 017 A 201 (-3.0A) 017 A 201 (-4.1A) 017 A 201 (-4.7A)	1.46A	1muiA-3ttpA: 19.4	1muiA-3ttpA: 79.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ttp	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	9	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 GLY A 49 ILE A 50 PRO A 81 ILE A 84	017 A 201 (-2.6A) 017 A 201 (-3.6A) 017 A 201 (-3.4A) 017 A 201 (-3.3A) 017 A 201 (-4.6A) 017 A 201 (-3.0A) 017 A 201 (-3.3A) 017 A 201 (-4.1A) 017 A 201 (-4.7A)	0.46A	1muiA-3ttpA: 19.4	1muiA-3ttpA: 79.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ttp	HIV-1 PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	6	GLY A 27 ALA A 28 ASP A 29 GLY A 48 PRO A 81 ILE A 84	017 A 201 (-3.6A) 017 A 201 (-3.4A) 017 A 201 (-3.3A) None 017 A 201 (-4.1A) 017 A 201 (-4.7A)	0.88A	1muiA-3ttpA: 19.4	1muiA-3ttpA: 79.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3u7s	POL POLYPROTEIN (Human immunodeficiency virus 1)	PF00077 (RVP)	8	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 GLY A 49 ILE A 50 PRO A 81	017 A 202 ( 2.5A) 017 A 201 ( 3.5A) 017 A 201 (-3.4A) 017 A 201 (-3.2A) 017 A 201 ( 4.0A) 017 A 202 (-2.9A) 017 A 201 ( 3.5A) 017 A 202 (-4.0A)	0.49A	1muiA-3u7sA: 19.5	1muiA-3u7sA: 79.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3uhl	PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	5	ASP A 25 GLY A 27 ALA A 28 ASP A 29 PRO A 81	None	0.60A	1muiA-3uhlA: 16.2	1muiA-3uhlA: 77.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3wgp	VITAMIN D3 RECEPTOR (Homo sapiens)	PF00104 (Hormone_recep)	5	GLY A 304 ASP A 299 VAL A 297 GLY A 164 ILE A 310	None	0.94A	1muiA-3wgpA: undetectable	1muiA-3wgpA: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4aip	FE-REGULATED PROTEIN B (Neisseria meningitidis)	PF00593 (TonB_dep_Rec) PF07715 (Plug)	5	GLY A 165 ALA A 166 ASP A 118 GLY A 159 ILE A 168	None	0.97A	1muiA-4aipA: undetectable	1muiA-4aipA: 9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ao7	ESTERASE (unidentified)	PF12146 (Hydrolase_4)	5	ALA A 125 VAL A 31 ILE A 119 PRO A 82 ILE A 79	None	0.75A	1muiA-4ao7A: undetectable	1muiA-4ao7A: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4c3y	3-KETOSTEROID DEHYDROGENASE (Rhodococcus erythropolis)	PF00890 (FAD_binding_2)	5	ALA A 180 GLY A 175 ILE A 174 PRO A 134 ILE A 109	None	0.98A	1muiA-4c3yA: undetectable	1muiA-4c3yA: 12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4db1	MYOSIN-7 (Homo sapiens)	PF00063 (Myosin_head) PF02736 (Myosin_N)	5	ALA A 261 ASP A 262 GLY A 458 ILE A 457 ILE A 220	None	0.97A	1muiA-4db1A: undetectable	1muiA-4db1A: 7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4hjh	PHOSPHOMANNOMUTASE (Brucella melitensis)	PF00408 (PGM_PMM_IV) PF02878 (PGM_PMM_I) PF02879 (PGM_PMM_II) PF02880 (PGM_PMM_III)	5	GLY A 272 ALA A 273 VAL A 293 GLY A 264 ILE A 266	None	0.95A	1muiA-4hjhA: undetectable	1muiA-4hjhA: 12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4io1	RIBOSE-5-PHOSPHATE ISOMERASE A (Francisella tularensis)	PF06026 (Rib_5-P_isom_A)	5	GLY A 103 ALA A 104 GLY A 202 ILE A 99 ILE A 174	CL A 301 (-3.5A) None None None None	0.94A	1muiA-4io1A: undetectable	1muiA-4io1A: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4iqy	O-ACETYL-ADP-RIBOSE DEACETYLASE MACROD2 (Homo sapiens)	PF01661 (Macro)	5	GLY A 191 ALA A 149 GLY A 146 ILE A 185 ILE A 153	None	0.97A	1muiA-4iqyA: undetectable	1muiA-4iqyA: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4jlw	GLUTATHIONE-INDEPEND ENT FORMALDEHYDE DEHYDROGENASE (Pseudomonas aeruginosa)	PF00107 (ADH_zinc_N) PF08240 (ADH_N)	6	GLY A 175 ALA A 202 VAL A 190 GLY A 298 ILE A 299 ILE A 192	None	1.50A	1muiA-4jlwA: undetectable	1muiA-4jlwA: 13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4kpn	NUCLEOSIDE N-RIBOHYDROLASE 1 (Physcomitrella patens)	PF01156 (IU_nuc_hydro)	5	GLY A 27 ASP A 29 GLY A 142 ILE A 51 ILE A 34	None CA A 400 ( 4.5A) CA A 400 ( 4.4A) None None	0.93A	1muiA-4kpnA: undetectable	1muiA-4kpnA: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4kpo	NUCLEOSIDE N-RIBOHYDROLASE 3 (Zea mays)	PF01156 (IU_nuc_hydro)	5	GLY A 10 ASP A 12 GLY A 124 ILE A 34 ILE A 17	None CA A 401 ( 4.8A) CA A 401 ( 4.3A) None None	0.90A	1muiA-4kpoA: undetectable	1muiA-4kpoA: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4moz	FRUCTOSE-BISPHOSPHAT E ALDOLASE (Slackia heliotrinireducens)	PF01791 (DeoC)	5	GLY A 242 ALA A 241 VAL A 211 GLY A 266 ILE A 259	None	0.98A	1muiA-4mozA: undetectable	1muiA-4mozA: 17.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4njv	PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	9	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 VAL A 32 GLY A 48 PRO A 81 ILE A 84	RIT A 500 (-2.4A) RIT A 500 (-3.9A) RIT A 500 (-3.6A) RIT A 500 (-3.2A) RIT A 500 (-4.8A) None RIT A 500 (-4.8A) RIT A 500 (-3.9A) RIT A 500 (-4.3A)	0.77A	1muiA-4njvA: 20.1	1muiA-4njvA: 87.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4njv	PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	10	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 VAL A 32 GLY A 49 ILE A 50 PRO A 81 ILE A 84	RIT A 500 (-2.4A) RIT A 500 (-3.9A) RIT A 500 (-3.6A) RIT A 500 (-3.2A) RIT A 500 (-4.8A) None RIT A 500 (-3.4A) RIT A 500 (-4.3A) RIT A 500 (-3.9A) RIT A 500 (-4.3A)	0.54A	1muiA-4njvA: 20.1	1muiA-4njvA: 87.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4o1e	DIHYDROPTEROATE SYNTHASE DHPS (Desulfitobacterium hafniense)	PF00809 (Pterin_bind)	5	ASP A 170 GLY A 172 ALA A 173 PRO A 131 ILE A 165	None	0.87A	1muiA-4o1eA: undetectable	1muiA-4o1eA: 16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4pcg	VP1 (Human polyomavirus 6)	PF00718 (Polyoma_coat)	6	ALA A 194 ASP A 144 VAL A 182 GLY A 147 ILE A 148 PRO A 188	None	1.39A	1muiA-4pcgA: undetectable	1muiA-4pcgA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4pcg	VP1 (Human polyomavirus 6)	PF00718 (Polyoma_coat)	6	ALA A 194 ASP A 195 ASP A 144 VAL A 182 GLY A 147 PRO A 188	None	1.38A	1muiA-4pcgA: undetectable	1muiA-4pcgA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4pch	VP1 (Human polyomavirus 7)	PF00718 (Polyoma_coat)	6	ALA A 191 ASP A 144 VAL A 179 GLY A 147 ILE A 148 PRO A 185	None	1.33A	1muiA-4pchA: undetectable	1muiA-4pchA: 17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4pyr	PUTATIVE BRANCHED-CHAIN AMINO ACID ABC TRANSPORTER (Chromobacterium violaceum)	PF04348 (LppC)	5	ALA A 343 VAL A 88 GLY A 336 ILE A 337 ILE A 86	None	0.88A	1muiA-4pyrA: undetectable	1muiA-4pyrA: 12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4qnn	PHOSPHOLIPASE A 1 FROM HORNET(VESPA BASALIS) VENOM (Vespa basalis)	PF00151 (Lipase)	5	ALA A 146 VAL A 109 GLY A 135 ILE A 134 ILE A 113	None	0.96A	1muiA-4qnnA: undetectable	1muiA-4qnnA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4rxt	SUGAR ABC TRANSPORTER (Agrobacterium tumefaciens)	PF13407 (Peripla_BP_4)	5	GLY A 269 ALA A 270 GLY A 255 ILE A 254 ILE A 242	None	0.98A	1muiA-4rxtA: undetectable	1muiA-4rxtA: 17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4tqk	LECTIN 2 (Agrocybe aegerita)	PF13517 (VCBS)	5	ASP A 345 GLY A 350 ASP A 290 VAL A 343 GLY A 371	None	0.88A	1muiA-4tqkA: undetectable	1muiA-4tqkA: 15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4x9n	L-ALPHA-GLYCEROPHOSP HATE OXIDASE (Mycoplasma pneumoniae)	PF01266 (DAO)	5	GLY A 344 ASP A 207 VAL A 358 GLY A 12 ILE A 357	None None None FAD A 401 (-3.2A) None	0.98A	1muiA-4x9nA: undetectable	1muiA-4x9nA: 14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4xr9	CALS8 (Micromonospora echinospora)	PF00984 (UDPG_MGDP_dh) PF03720 (UDPG_MGDP_dh_C) PF03721 (UDPG_MGDP_dh_N)	5	ASP A 248 VAL A 249 GLY A 452 ILE A 451 ILE A 250	None	0.95A	1muiA-4xr9A: undetectable	1muiA-4xr9A: 13.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4ydf	HTLV-1 PROTEASE (Primate T-lymphotropic virus 1)	PF00077 (RVP)	7	ASP A 32 GLY A 34 ALA A 35 ASP A 36 VAL A 39 GLY A 58 ILE A 100	4B1 A 201 (-2.9A) 4B1 A 201 ( 4.6A) 4B1 A 201 (-3.6A) 4B1 A 201 (-4.4A) None 4B1 A 201 (-3.4A) 4B1 A 201 (-4.8A)	0.53A	1muiA-4ydfA: 13.1	1muiA-4ydfA: 31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4yzg	PROTEIN PHOSPHATASE 2C 57 (Arabidopsis thaliana)	PF00481 (PP2C)	5	ASP A 238 GLY A 160 GLY A 179 ILE A 178 ILE A 230	None	0.96A	1muiA-4yzgA: undetectable	1muiA-4yzgA: 17.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5b18	PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	5	GLY A 27 ALA A 28 ASP A 29 ASP A 30 ILE A 84	None	0.28A	1muiA-5b18A: 17.9	1muiA-5b18A: 76.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5b18	PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	5	GLY A 27 ALA A 28 ASP A 29 GLY A 49 ILE A 84	None	0.69A	1muiA-5b18A: 17.9	1muiA-5b18A: 76.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5g5g	PUTATIVE XANTHINE DEHYDROGENASE YAGT IRON-SULFUR-BINDING SUBUNIT (Escherichia coli)	PF00111 (Fer2) PF01799 (Fer2_2)	5	GLY A 211 ALA A 212 ASP A 154 GLY A 159 ILE A 216	None None None FES A 230 (-4.2A) None	0.85A	1muiA-5g5gA: undetectable	1muiA-5g5gA: 24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5i3s	INOSITOL MONOPHOSPHATASE FAMILY PROTEIN (Staphylococcus aureus)	PF00459 (Inositol_P)	5	GLY A 131 ALA A 132 VAL A 189 GLY A 135 ILE A 215	None	0.90A	1muiA-5i3sA: undetectable	1muiA-5i3sA: 18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5j1k	TOXR-ACTIVATED GENE (TAGE) (Helicobacter pylori)	PF01551 (Peptidase_M23)	5	GLY A 230 ALA A 180 VAL A 186 GLY A 234 ILE A 227	None	0.89A	1muiA-5j1kA: undetectable	1muiA-5j1kA: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5j1l	TOXR-ACTIVATED GENE (TAGE) (Helicobacter pylori)	PF01551 (Peptidase_M23)	5	GLY B 230 ALA B 180 VAL B 186 GLY B 234 ILE B 227	None	0.87A	1muiA-5j1lB: undetectable	1muiA-5j1lB: 19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5jxk	ASP/GLU-SPECIFIC DIPEPTIDYL-PEPTIDASE (Porphyromonas endodontalis)	PF10459 (Peptidase_S46)	5	GLY A 583 ALA A 594 VAL A 263 ILE A 689 ILE A 581	None	0.90A	1muiA-5jxkA: undetectable	1muiA-5jxkA: 8.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5t2z	PROTEASE (Human immunodeficiency virus 1)	PF00077 (RVP)	10	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 VAL A 32 GLY A 49 ILE A 50 PRO A 81 ILE A 84	None	0.50A	1muiA-5t2zA: 19.8	1muiA-5t2zA: 80.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5w1a	MYOSIN HEAVY CHAIN, MUSCLE (Drosophila melanogaster)	no annotation	6	GLY A 259 ALA A 260 ASP A 261 VAL A 219 GLY A 457 ILE A 456	None	1.31A	1muiA-5w1aA: undetectable	1muiA-5w1aA: 19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5x1n	VANILLATE/3-O-METHYL GALLATE O-DEMETHYLASE (Sphingobium sp. SYK-6)	PF01571 (GCV_T) PF08669 (GCV_T_C)	6	GLY A 168 ALA A 171 ASP A 173 GLY A 238 ILE A 240 ILE A 166	None	1.25A	1muiA-5x1nA: undetectable	1muiA-5x1nA: 15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5y6q	ALDEHYDE OXIDASE SMALL SUBUNIT (Methylobacillus sp. KY4400)	no annotation	5	GLY A 141 ALA A 142 ASP A 99 GLY A 104 ILE A 146	None None None FES A 202 (-4.1A) None	0.97A	1muiA-5y6qA: undetectable	1muiA-5y6qA: 19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6f8l	- (-)	no annotation	5	ASP G 401 GLY G 403 ALA G 404 VAL G 429 GLY G 425	None	0.90A	1muiA-6f8lG: undetectable	1muiA-6f8lG: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6fiv	RETROPEPSIN (Feline immunodeficiency virus)	PF00077 (RVP)	5	ASP A 30 GLY A 32 ALA A 33 ASP A 34 GLY A 58	3TL A 201 (-3.5A) 3TL A 201 (-3.4A) 3TL A 201 (-4.0A) 3TL A 201 (-3.9A) 3TL A 201 (-3.4A)	0.30A	1muiA-6fivA: 15.7	1muiA-6fivA: 29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6upj	HIV-2 PROTEASE (Human immunodeficiency virus 2)	PF00077 (RVP)	6	ASP A 25 ALA A 28 ASP A 29 GLY A 48 PRO A 81 ILE A 84	NIU A 100 (-2.8A) NIU A 100 (-3.6A) None None None None	0.91A	1muiA-6upjA: 18.1	1muiA-6upjA: 48.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6upj	HIV-2 PROTEASE (Human immunodeficiency virus 2)	PF00077 (RVP)	8	ASP A 25 GLY A 27 ALA A 28 ASP A 29 ASP A 30 GLY A 49 PRO A 81 ILE A 84	NIU A 100 (-2.8A) NIU A 100 (-4.5A) NIU A 100 (-3.6A) None None NIU A 100 ( 3.8A) None None	0.62A	1muiA-6upjA: 18.1	1muiA-6upjA: 48.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6upj	HIV-2 PROTEASE (Human immunodeficiency virus 2)	PF00077 (RVP)	8	ASP A 25 GLY A 27 ASP A 29 ASP A 30 GLY A 49 ILE A 50 PRO A 81 ILE A 84	NIU A 100 (-2.8A) NIU A 100 (-4.5A) None None NIU A 100 ( 3.8A) NIU A 100 (-3.9A) None None	0.78A	1muiA-6upjA: 18.1	1muiA-6upjA: 48.48

[["1MUI_B_AB1B100_1","1b4e","Escherichia coli","PROTEIN (5-AMINOLEVULINIC ACID DEHYDRATASE)","PF00490(ALAD)",5,"GLY A 305;ALA A 306;ASP A 307;ILE A 255;ILE A 301","None","0.95A","1muiA-1b4eA:undetectable","1muiA-1b4eA:13.18"],["1MUI_B_AB1B100_1","1bu8","Rattus norvegicus","PROTEIN (PANCREATIC LIPASE RELATED PROTEIN 2)","PF00151(Lipase);PF01477(PLAT)",5,"ALA A 161;VAL A 124;GLY A 150;ILE A 149;ILE A 128","None","0.94A","1muiA-1bu8A:undetectable","1muiA-1bu8A:14.05"],["1MUI_B_AB1B100_1","1czi","Bos taurus","CHYMOSIN","PF00026(Asp)",5,"ASP E 215;GLY E 217;VAL E 222;GLY E  76;ILE E 300","None","0.84A","1muiA-1cziE:6.8","1muiA-1cziE:18.15"],["1MUI_B_AB1B100_1","1ea6","Homo sapiens","PMS1 PROTEIN HOMOLOG 2","PF01119(DNA_mis_repair);PF13589(HATPase_c_3)",5,"GLY A  50;ALA A  51;ASP A  70;VAL A 200;ILE A 198","None;None;ADP A1366 (-3.4A);None;None","0.97A","1muiA-1ea6A:undetectable","1muiA-1ea6A:14.45"],["1MUI_B_AB1B100_1","1fob","Aspergillus aculeatus","BETA-1,4-GALACTANASE","PF07745(Glyco_hydro_53)",6,"GLY A  40;ALA A  39;ASP A  38;VAL A 324;ILE A  44;ILE A 328","None","1.11A","1muiA-1fobA:undetectable","1muiA-1fobA:14.58"],["1MUI_B_AB1B100_1","1hrd","[Clostridium] symbiosum","GLUTAMATE DEHYDROGENASE","PF00208(ELFV_dehydrog);PF02812(ELFV_dehydrog_N)",6,"GLY A 300;ALA A 296;ASP A 297;ASP A 294;VAL A 292;ILE A 266","None","1.46A","1muiA-1hrdA:undetectable","1muiA-1hrdA:11.03"],["1MUI_B_AB1B100_1","1hvc","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",6,"ASP A  25;ALA A  28;ASP A  29;GLY A  49;ILE A  50;ILE A  84","A79 A 800 (-2.7A);A79 A 800 (-3.1A);A79 A 800 (-2.8A);A79 A 800 ( 3.7A);A79 A 800 (-3.8A);A79 A 800 (-3.6A)","1.22A","1muiA-1hvcA:13.7","1muiA-1hvcA:100.00"],["1MUI_B_AB1B100_1","1hvc","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",10,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;VAL A  32;GLY A  49;ILE A  50;PRO A  81;ILE A  84","A79 A 800 (-2.7A);A79 A 800 (-3.0A);A79 A 800 (-3.1A);A79 A 800 (-2.8A);A79 A 800 ( 4.9A);A79 A 800 ( 4.4A);A79 A 800 ( 3.7A);A79 A 800 (-3.8A);A79 A 800 ( 3.9A);A79 A 800 (-3.6A)","0.56A","1muiA-1hvcA:13.7","1muiA-1hvcA:100.00"],["1MUI_B_AB1B100_1","1hvc","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",10,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;VAL A  32;GLY A  49;ILE A  50;PRO A  81;ILE A  84","A79 A 800 (-2.8A);A79 A 800 (-3.0A);A79 A 800 (-3.2A);A79 A 800 (-2.7A);A79 A 800 ( 4.7A);A79 A 800 ( 4.3A);A79 A 800 (-3.4A);A79 A 800 ( 4.0A);A79 A 800 ( 3.4A);A79 A 800 (-3.8A)","0.46A","1muiA-1hvcA:13.7","1muiA-1hvcA:100.00"],["1MUI_B_AB1B100_1","1hvc","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",7,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;GLY A  48;PRO A  81;ILE A  84","A79 A 800 (-2.8A);A79 A 800 (-3.0A);A79 A 800 (-3.2A);A79 A 800 (-2.7A);A79 A 800 (-4.1A);A79 A 800 ( 3.4A);A79 A 800 (-3.8A)","0.89A","1muiA-1hvcA:13.7","1muiA-1hvcA:100.00"],["1MUI_B_AB1B100_1","1hvc","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",7,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;VAL A  32;GLY A  48;ILE A  84","A79 A 800 (-2.7A);A79 A 800 (-3.0A);A79 A 800 (-3.1A);A79 A 800 (-2.8A);A79 A 800 ( 4.4A);A79 A 800 (-3.6A);A79 A 800 (-3.6A)","0.81A","1muiA-1hvcA:13.7","1muiA-1hvcA:100.00"],["1MUI_B_AB1B100_1","1kae","Escherichia coli","HISTIDINOL DEHYDROGENASE","PF00815(Histidinol_dh)",5,"GLY A 227;ALA A 228;ASP A 204;GLY A 196;ILE A 206","None","0.87A","1muiA-1kaeA:undetectable","1muiA-1kaeA:13.23"],["1MUI_B_AB1B100_1","1l5j","Escherichia coli","ACONITATE HYDRATASE 2","PF00330(Aconitase);PF06434(Aconitase_2_N);PF11791(Aconitase_B_N)",5,"GLY A 721;ALA A 720;GLY A 715;ILE A 714;ILE A 707","None","0.95A","1muiA-1l5jA:undetectable","1muiA-1l5jA:9.25"],["1MUI_B_AB1B100_1","1lk5","Pyrococcus horikoshii","D-RIBOSE-5-PHOSPHATE ISOMERASE","PF06026(Rib_5-P_isom_A)",5,"GLY A 101;ALA A 102;GLY A 207;ILE A  97;ILE A 179"," CL A1001 (-3.4A);None;None;None;None","0.90A","1muiA-1lk5A:undetectable","1muiA-1lk5A:18.07"],["1MUI_B_AB1B100_1","1m0s","Haemophilus influenzae","RIBOSE-5-PHOSPHATE ISOMERASE A","PF06026(Rib_5-P_isom_A)",5,"GLY A  97;ALA A  98;GLY A 197;ILE A  93;ILE A 169","CIT A 501 (-3.1A);None;None;None;None","0.98A","1muiA-1m0sA:undetectable","1muiA-1m0sA:22.40"],["1MUI_B_AB1B100_1","1orf","Homo sapiens","GRANZYME A","PF00089(Trypsin)",5,"GLY A  44;ALA A  45;GLY A 211;ILE A 229;ILE A  47","None","0.96A","1muiA-1orfA:undetectable","1muiA-1orfA:16.89"],["1MUI_B_AB1B100_1","1q9p","Homo sapiens","HIV-1 PROTEASE","PF00077(RVP)",8,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;VAL A  32;PRO A  81;ILE A  84","None","0.79A","1muiA-1q9pA:10.4","1muiA-1q9pA:94.74"],["1MUI_B_AB1B100_1","1siv","Simian immunodeficiency virus","SIV PROTEASE","PF00077(RVP)",6,"ASP A  25;ALA A  28;ASP A  29;GLY A  49;PRO A  81;ILE A  84","None","1.36A","1muiA-1sivA:18.2","1muiA-1sivA:50.51"],["1MUI_B_AB1B100_1","1siv","Simian immunodeficiency virus","SIV PROTEASE","PF00077(RVP)",9,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;GLY A  49;ILE A  50;PRO A  81;ILE A  84","None","0.52A","1muiA-1sivA:18.2","1muiA-1sivA:50.51"],["1MUI_B_AB1B100_1","1siv","Simian immunodeficiency virus","SIV PROTEASE","PF00077(RVP)",7,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;GLY A  48;PRO A  81;ILE A  84","None","0.85A","1muiA-1sivA:18.2","1muiA-1sivA:50.51"],["1MUI_B_AB1B100_1","1v43","Pyrococcus horikoshii","SUGAR-BINDING TRANSPORT ATP-BINDING PROTEIN","PF00005(ABC_tran);PF08402(TOBE_2)",5,"ALA A 206;ASP A 202;VAL A 215;GLY A 244;ILE A 213","None","0.89A","1muiA-1v43A:undetectable","1muiA-1v43A:14.05"],["1MUI_B_AB1B100_1","1xi3","Pyrococcus furiosus","THIAMINE PHOSPHATE PYROPHOSPHORYLASE","PF02581(TMP-TENI)",5,"GLY A 127;ALA A 126;VAL A 150;GLY A 178;ILE A 179","None","0.93A","1muiA-1xi3A:undetectable","1muiA-1xi3A:18.98"],["1MUI_B_AB1B100_1","1xtz","Saccharomyces cerevisiae","RIBOSE-5-PHOSPHATE ISOMERASE","PF06026(Rib_5-P_isom_A)",5,"GLY A 123;ALA A 124;GLY A 235;ILE A 119;ILE A 207","None","0.98A","1muiA-1xtzA:undetectable","1muiA-1xtzA:21.55"],["1MUI_B_AB1B100_1","1yg0","Helicobacter pylori","COP ASSOCIATED PROTEIN","PF00403(HMA)",5,"GLY A  62;ALA A  61;ASP A  60;VAL A  23;ILE A  19","None","0.93A","1muiA-1yg0A:undetectable","1muiA-1yg0A:19.00"],["1MUI_B_AB1B100_1","2bc0","Streptococcus pyogenes","NADH OXIDASE","PF02852(Pyr_redox_dim);PF07992(Pyr_redox_2)",5,"GLY A 453;ALA A 454;ASP A 456;ILE A 387;ILE A 426","None","0.77A","1muiA-2bc0A:undetectable","1muiA-2bc0A:12.87"],["1MUI_B_AB1B100_1","2fmb","Equine infectious anemia virus","EQUINE INFECTIOUS ANEMIA VIRUS PROTEASE","PF00077(RVP)",7,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;VAL A  32;GLY A  54;ILE A  89","LP1 A 201 (-2.3A);LP1 A 201 (-3.8A);LP1 A 201 (-3.5A);LP1 A 201 (-3.6A);None;LP1 A 201 (-3.6A);LP1 A 201 (-4.2A)","0.84A","1muiA-2fmbA:15.3","1muiA-2fmbA:30.77"],["1MUI_B_AB1B100_1","2fmb","Equine infectious anemia virus","EQUINE INFECTIOUS ANEMIA VIRUS PROTEASE","PF00077(RVP)",8,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;VAL A  32;GLY A  55;PRO A  86;ILE A  89","LP1 A 201 (-2.3A);LP1 A 201 (-3.8A);LP1 A 201 (-3.5A);LP1 A 201 (-3.6A);None;LP1 A 201 (-3.4A);LP1 A 201 (-3.9A);LP1 A 201 (-4.2A)","0.52A","1muiA-2fmbA:15.3","1muiA-2fmbA:30.77"],["1MUI_B_AB1B100_1","2g4r","Mycobacterium tuberculosis","MOLYBDOPTERIN BIOSYNTHESIS MOG PROTEIN","PF00994(MoCF_biosynth)",5,"GLY A 115;ASP A  97;GLY A 118;ILE A 125;ILE A  99","None;TRS A 301 (-2.8A);None;None;None","0.88A","1muiA-2g4rA:undetectable","1muiA-2g4rA:20.37"],["1MUI_B_AB1B100_1","2isq","Arabidopsis thaliana","CYSTEINE SYNTHASE","PF00291(PALP)",5,"GLY A 190;ALA A 189;GLY A 183;ILE A 180;PRO A 296","None;None;PLP A 400 (-3.4A);PLP A 400 (-4.9A);PLP A 400 (-4.0A)","0.81A","1muiA-2isqA:undetectable","1muiA-2isqA:15.94"],["1MUI_B_AB1B100_1","2it1","Pyrococcus horikoshii","362AA LONG HYPOTHETICAL MALTOSE\/MALTODEXTRIN TRANSPORT ATP-BINDING PROTEIN","PF00005(ABC_tran)",5,"ALA A 197;ASP A 193;VAL A 206;GLY A 235;ILE A 204","None","0.93A","1muiA-2it1A:undetectable","1muiA-2it1A:13.93"],["1MUI_B_AB1B100_1","2odp","Homo sapiens","COMPLEMENT C2","PF00089(Trypsin);PF00092(VWA)",5,"GLY A 474;ALA A 475;GLY A 675;ILE A 710;ILE A 477","None","0.96A","1muiA-2odpA:undetectable","1muiA-2odpA:10.87"],["1MUI_B_AB1B100_1","2p3e","Aquifex aeolicus","DIAMINOPIMELATE DECARBOXYLASE","PF00278(Orn_DAP_Arg_deC);PF02784(Orn_Arg_deC_N)",5,"ALA A 355;VAL A 371;GLY A 345;ILE A 308;ILE A 328","None","0.84A","1muiA-2p3eA:undetectable","1muiA-2p3eA:13.60"],["1MUI_B_AB1B100_1","2rkf","Human immunodeficiency virus 1","PROTEASE RETROPEPSIN","PF00077(RVP)",6,"ASP A  25;ALA A  28;ASP A  29;GLY A  49;PRO A  81;ILE A  84","AB1 A 501 (-2.4A);AB1 A 501 (-3.5A);AB1 A 501 ( 3.3A);AB1 A 501 (-3.5A);AB1 A 501 (-4.2A);AB1 A 501 ( 4.2A)","1.42A","1muiA-2rkfA:20.7","1muiA-2rkfA:87.88"],["1MUI_B_AB1B100_1","2rkf","Human immunodeficiency virus 1","PROTEASE RETROPEPSIN","PF00077(RVP)",9,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;GLY A  49;ILE A  50;PRO A  81;ILE A  84","AB1 A 501 (-2.4A);AB1 A 501 (-3.9A);AB1 A 501 (-3.5A);AB1 A 501 ( 3.3A);AB1 A 501 (-3.8A);AB1 A 501 (-3.5A);AB1 A 501 (-3.8A);AB1 A 501 (-4.2A);AB1 A 501 ( 4.2A)","0.45A","1muiA-2rkfA:20.7","1muiA-2rkfA:87.88"],["1MUI_B_AB1B100_1","2rkf","Human immunodeficiency virus 1","PROTEASE RETROPEPSIN","PF00077(RVP)",6,"GLY A  27;ALA A  28;ASP A  29;GLY A  48;PRO A  81;ILE A  84","AB1 A 501 (-3.9A);AB1 A 501 (-3.5A);AB1 A 501 ( 3.3A);AB1 A 501 (-4.2A);AB1 A 501 (-4.2A);AB1 A 501 ( 4.2A)","0.80A","1muiA-2rkfA:20.7","1muiA-2rkfA:87.88"],["1MUI_B_AB1B100_1","2rsp","Rous sarcoma virus","RSV PROTEASE","PF00077(RVP)",5,"ASP A  37;GLY A  39;ALA A  40;ASP A  41;ILE A 108","None","0.32A","1muiA-2rspA:13.0","1muiA-2rspA:32.80"],["1MUI_B_AB1B100_1","2w45","Human gammaherpesvirus 4","ALKALINE EXONUCLEASE","PF01771(Herpes_alk_exo)",5,"GLY A 442;ALA A 441;GLY A 461;PRO A  42;ILE A 197","None","0.98A","1muiA-2w45A:undetectable","1muiA-2w45A:13.45"],["1MUI_B_AB1B100_1","2w58","Geobacillus kaustophilus","PRIMOSOME COMPONENT (HELICASE LOADER)","PF01695(IstB_IS21)",5,"GLY A 232;ASP A 230;ASP A 229;GLY A 168;PRO A 300","None;None; MG A1311 ( 3.9A);None;None","0.89A","1muiA-2w58A:undetectable","1muiA-2w58A:20.25"],["1MUI_B_AB1B100_1","3a0f","Geotrichum sp. M128","XYLOGLUCANASE","no annotation",5,"GLY A 119;ALA A 120;ASP A  34;GLY A 127;ILE A 177","None","0.96A","1muiA-3a0fA:undetectable","1muiA-3a0fA:8.40"],["1MUI_B_AB1B100_1","3b8b","Bacteroides thetaiotaomicron","CYSQ, SULFITE SYNTHESIS PATHWAY PROTEIN","PF00459(Inositol_P)",6,"ALA A   6;ASP A   5;VAL A 112;GLY A  11;ILE A  14;ILE A 100","None","1.42A","1muiA-3b8bA:undetectable","1muiA-3b8bA:16.55"],["1MUI_B_AB1B100_1","3g1u","Leishmania major","ADENOSYLHOMOCYSTEINASE","PF00670(AdoHcyase_NAD);PF05221(AdoHcyase)",5,"GLY A 383;ALA A 386;VAL A 388;GLY A 151;ILE A 149","None","0.98A","1muiA-3g1uA:undetectable","1muiA-3g1uA:14.19"],["1MUI_B_AB1B100_1","3g7r","Streptomyces coelicolor","PUTATIVE TRANSCRIPTIONAL REGULATOR","PF00440(TetR_N)",5,"GLY A 166;ALA A 167;VAL A  99;GLY A 186;ILE A  98","None;None;None;None;EDO A 960 ( 4.8A)","0.96A","1muiA-3g7rA:undetectable","1muiA-3g7rA:18.69"],["1MUI_B_AB1B100_1","3gve","Bacillus subtilis","YFKN PROTEIN","PF00149(Metallophos)",5,"GLY A 121;ALA A 122;ASP A 123;ILE A  89;ILE A 126","None","0.76A","1muiA-3gveA:undetectable","1muiA-3gveA:14.80"],["1MUI_B_AB1B100_1","3i5g","Doryteuthis pealeii","MYOSIN HEAVY CHAIN ISOFORM A","PF00063(Myosin_head);PF00612(IQ);PF02736(Myosin_N)",6,"GLY A 264;ALA A 265;ASP A 266;GLY A 460;ILE A 459;ILE A 224","None","1.03A","1muiA-3i5gA:undetectable","1muiA-3i5gA:8.00"],["1MUI_B_AB1B100_1","3ifu","Porcine reproductive and respiratory syndrome virus","NON-STRUCTURAL PROTEIN","PF05410(Peptidase_C31)",5,"GLY A 154;ALA A 155;VAL A 158;PRO A 134;ILE A 131","None","0.96A","1muiA-3ifuA:undetectable","1muiA-3ifuA:23.78"],["1MUI_B_AB1B100_1","3mws","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",6,"ASP A  25;ALA A  28;ASP A  29;GLY A  49;PRO A  81;ILE A  84","None","1.47A","1muiA-3mwsA:19.3","1muiA-3mwsA:78.79"],["1MUI_B_AB1B100_1","3mws","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",9,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;VAL A  32;GLY A  48;PRO A  81;ILE A  84","None","0.84A","1muiA-3mwsA:19.3","1muiA-3mwsA:78.79"],["1MUI_B_AB1B100_1","3mws","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",10,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;VAL A  32;GLY A  49;ILE A  50;PRO A  81;ILE A  84","None","0.64A","1muiA-3mwsA:19.3","1muiA-3mwsA:78.79"],["1MUI_B_AB1B100_1","3pv2","Legionella fallonii","DEGQ","PF13180(PDZ_2);PF13365(Trypsin_2)",5,"GLY A 287;ALA A 286;VAL A 321;GLY A 249;ILE A 323","None","0.88A","1muiA-3pv2A:undetectable","1muiA-3pv2A:12.81"],["1MUI_B_AB1B100_1","3rmg","Bacteroides thetaiotaomicron","OCTAPRENYL-DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"ASP A 212;ASP A 213;GLY A 205;ILE A 204;ILE A 289","None","0.96A","1muiA-3rmgA:undetectable","1muiA-3rmgA:12.69"],["1MUI_B_AB1B100_1","3slz","Murine leukemia virus","GAG-PRO-POL POLYPROTEIN","PF00077(RVP)",5,"ASP A  32;GLY A  34;ALA A  35;VAL A  39;GLY A  56","3TL A 126 (-2.4A);3TL A 126 (-3.1A);3TL A 126 ( 4.0A);None;3TL A 126 (-3.4A)","0.56A","1muiA-3slzA:11.2","1muiA-3slzA:27.41"],["1MUI_B_AB1B100_1","3slz","Murine leukemia virus","GAG-PRO-POL POLYPROTEIN","PF00077(RVP)",5,"ASP A  32;GLY A  34;ALA A  35;VAL A  39;PRO A  89","3TL A 126 (-2.4A);3TL A 126 (-3.1A);3TL A 126 ( 4.0A);None;3TL A 126 (-4.0A)","0.67A","1muiA-3slzA:11.2","1muiA-3slzA:27.41"],["1MUI_B_AB1B100_1","3t3c","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",9,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;VAL A  32;GLY A  49;ILE A  50;PRO A  81","017 A 201 (-2.6A);017 A 201 (-3.4A);017 A 201 (-3.5A);017 A 201 (-3.5A);017 A 201 (-4.2A);None;017 A 201 (-4.0A);017 A 201 (-3.3A);None","0.79A","1muiA-3t3cA:18.2","1muiA-3t3cA:77.78"],["1MUI_B_AB1B100_1","3ttp","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",6,"ASP A  25;ALA A  28;ASP A  29;GLY A  49;PRO A  81;ILE A  84","017 A 201 (-2.6A);017 A 201 (-3.4A);017 A 201 (-3.3A);017 A 201 (-3.0A);017 A 201 (-4.1A);017 A 201 (-4.7A)","1.46A","1muiA-3ttpA:19.4","1muiA-3ttpA:79.80"],["1MUI_B_AB1B100_1","3ttp","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",9,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;GLY A  49;ILE A  50;PRO A  81;ILE A  84","017 A 201 (-2.6A);017 A 201 (-3.6A);017 A 201 (-3.4A);017 A 201 (-3.3A);017 A 201 (-4.6A);017 A 201 (-3.0A);017 A 201 (-3.3A);017 A 201 (-4.1A);017 A 201 (-4.7A)","0.46A","1muiA-3ttpA:19.4","1muiA-3ttpA:79.80"],["1MUI_B_AB1B100_1","3ttp","Human immunodeficiency virus 1","HIV-1 PROTEASE","PF00077(RVP)",6,"GLY A  27;ALA A  28;ASP A  29;GLY A  48;PRO A  81;ILE A  84","017 A 201 (-3.6A);017 A 201 (-3.4A);017 A 201 (-3.3A);None;017 A 201 (-4.1A);017 A 201 (-4.7A)","0.88A","1muiA-3ttpA:19.4","1muiA-3ttpA:79.80"],["1MUI_B_AB1B100_1","3u7s","Human immunodeficiency virus 1","POL POLYPROTEIN","PF00077(RVP)",8,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;GLY A  49;ILE A  50;PRO A  81","017 A 202 ( 2.5A);017 A 201 ( 3.5A);017 A 201 (-3.4A);017 A 201 (-3.2A);017 A 201 ( 4.0A);017 A 202 (-2.9A);017 A 201 ( 3.5A);017 A 202 (-4.0A)","0.49A","1muiA-3u7sA:19.5","1muiA-3u7sA:79.80"],["1MUI_B_AB1B100_1","3uhl","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP)",5,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;PRO A  81","None","0.60A","1muiA-3uhlA:16.2","1muiA-3uhlA:77.78"],["1MUI_B_AB1B100_1","3wgp","Homo sapiens","VITAMIN D3 RECEPTOR","PF00104(Hormone_recep)",5,"GLY A 304;ASP A 299;VAL A 297;GLY A 164;ILE A 310","None","0.94A","1muiA-3wgpA:undetectable","1muiA-3wgpA:17.50"],["1MUI_B_AB1B100_1","4aip","Neisseria meningitidis","FE-REGULATED PROTEIN B","PF00593(TonB_dep_Rec);PF07715(Plug)",5,"GLY A 165;ALA A 166;ASP A 118;GLY A 159;ILE A 168","None","0.97A","1muiA-4aipA:undetectable","1muiA-4aipA:9.04"],["1MUI_B_AB1B100_1","4ao7","unidentified","ESTERASE","PF12146(Hydrolase_4)",5,"ALA A 125;VAL A  31;ILE A 119;PRO A  82;ILE A  79","None","0.75A","1muiA-4ao7A:undetectable","1muiA-4ao7A:21.11"],["1MUI_B_AB1B100_1","4c3y","Rhodococcus erythropolis","3-KETOSTEROID DEHYDROGENASE","PF00890(FAD_binding_2)",5,"ALA A 180;GLY A 175;ILE A 174;PRO A 134;ILE A 109","None","0.98A","1muiA-4c3yA:undetectable","1muiA-4c3yA:12.03"],["1MUI_B_AB1B100_1","4db1","Homo sapiens","MYOSIN-7","PF00063(Myosin_head);PF02736(Myosin_N)",5,"ALA A 261;ASP A 262;GLY A 458;ILE A 457;ILE A 220","None","0.97A","1muiA-4db1A:undetectable","1muiA-4db1A:7.39"],["1MUI_B_AB1B100_1","4hjh","Brucella melitensis","PHOSPHOMANNOMUTASE","PF00408(PGM_PMM_IV);PF02878(PGM_PMM_I);PF02879(PGM_PMM_II);PF02880(PGM_PMM_III)",5,"GLY A 272;ALA A 273;VAL A 293;GLY A 264;ILE A 266","None","0.95A","1muiA-4hjhA:undetectable","1muiA-4hjhA:12.33"],["1MUI_B_AB1B100_1","4io1","Francisella tularensis","RIBOSE-5-PHOSPHATE ISOMERASE A","PF06026(Rib_5-P_isom_A)",5,"GLY A 103;ALA A 104;GLY A 202;ILE A  99;ILE A 174"," CL A 301 (-3.5A);None;None;None;None","0.94A","1muiA-4io1A:undetectable","1muiA-4io1A:20.36"],["1MUI_B_AB1B100_1","4iqy","Homo sapiens","O-ACETYL-ADP-RIBOSE DEACETYLASE MACROD2","PF01661(Macro)",5,"GLY A 191;ALA A 149;GLY A 146;ILE A 185;ILE A 153","None","0.97A","1muiA-4iqyA:undetectable","1muiA-4iqyA:19.01"],["1MUI_B_AB1B100_1","4jlw","Pseudomonas aeruginosa","GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE","PF00107(ADH_zinc_N);PF08240(ADH_N)",6,"GLY A 175;ALA A 202;VAL A 190;GLY A 298;ILE A 299;ILE A 192","None","1.50A","1muiA-4jlwA:undetectable","1muiA-4jlwA:13.73"],["1MUI_B_AB1B100_1","4kpn","Physcomitrella patens","NUCLEOSIDE N-RIBOHYDROLASE 1","PF01156(IU_nuc_hydro)",5,"GLY A  27;ASP A  29;GLY A 142;ILE A  51;ILE A  34","None; CA A 400 ( 4.5A); CA A 400 ( 4.4A);None;None","0.93A","1muiA-4kpnA:undetectable","1muiA-4kpnA:15.69"],["1MUI_B_AB1B100_1","4kpo","Zea mays","NUCLEOSIDE N-RIBOHYDROLASE 3","PF01156(IU_nuc_hydro)",5,"GLY A  10;ASP A  12;GLY A 124;ILE A  34;ILE A  17","None; CA A 401 ( 4.8A); CA A 401 ( 4.3A);None;None","0.90A","1muiA-4kpoA:undetectable","1muiA-4kpoA:17.39"],["1MUI_B_AB1B100_1","4moz","Slackia heliotrinireducens","FRUCTOSE-BISPHOSPHATE ALDOLASE","PF01791(DeoC)",5,"GLY A 242;ALA A 241;VAL A 211;GLY A 266;ILE A 259","None","0.98A","1muiA-4mozA:undetectable","1muiA-4mozA:17.10"],["1MUI_B_AB1B100_1","4njv","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP)",9,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;VAL A  32;GLY A  48;PRO A  81;ILE A  84","RIT A 500 (-2.4A);RIT A 500 (-3.9A);RIT A 500 (-3.6A);RIT A 500 (-3.2A);RIT A 500 (-4.8A);None;RIT A 500 (-4.8A);RIT A 500 (-3.9A);RIT A 500 (-4.3A)","0.77A","1muiA-4njvA:20.1","1muiA-4njvA:87.88"],["1MUI_B_AB1B100_1","4njv","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP)",10,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;VAL A  32;GLY A  49;ILE A  50;PRO A  81;ILE A  84","RIT A 500 (-2.4A);RIT A 500 (-3.9A);RIT A 500 (-3.6A);RIT A 500 (-3.2A);RIT A 500 (-4.8A);None;RIT A 500 (-3.4A);RIT A 500 (-4.3A);RIT A 500 (-3.9A);RIT A 500 (-4.3A)","0.54A","1muiA-4njvA:20.1","1muiA-4njvA:87.88"],["1MUI_B_AB1B100_1","4o1e","Desulfitobacterium hafniense","DIHYDROPTEROATE SYNTHASE DHPS","PF00809(Pterin_bind)",5,"ASP A 170;GLY A 172;ALA A 173;PRO A 131;ILE A 165","None","0.87A","1muiA-4o1eA:undetectable","1muiA-4o1eA:16.73"],["1MUI_B_AB1B100_1","4pcg","Human polyomavirus 6","VP1","PF00718(Polyoma_coat)",6,"ALA A 194;ASP A 144;VAL A 182;GLY A 147;ILE A 148;PRO A 188","None","1.39A","1muiA-4pcgA:undetectable","1muiA-4pcgA:18.56"],["1MUI_B_AB1B100_1","4pcg","Human polyomavirus 6","VP1","PF00718(Polyoma_coat)",6,"ALA A 194;ASP A 195;ASP A 144;VAL A 182;GLY A 147;PRO A 188","None","1.38A","1muiA-4pcgA:undetectable","1muiA-4pcgA:18.56"],["1MUI_B_AB1B100_1","4pch","Human polyomavirus 7","VP1","PF00718(Polyoma_coat)",6,"ALA A 191;ASP A 144;VAL A 179;GLY A 147;ILE A 148;PRO A 185","None","1.33A","1muiA-4pchA:undetectable","1muiA-4pchA:17.18"],["1MUI_B_AB1B100_1","4pyr","Chromobacterium violaceum","PUTATIVE BRANCHED-CHAIN AMINO ACID ABC TRANSPORTER","PF04348(LppC)",5,"ALA A 343;VAL A  88;GLY A 336;ILE A 337;ILE A  86","None","0.88A","1muiA-4pyrA:undetectable","1muiA-4pyrA:12.88"],["1MUI_B_AB1B100_1","4qnn","Vespa basalis","PHOSPHOLIPASE A 1  FROM HORNET(VESPA BASALIS) VENOM","PF00151(Lipase)",5,"ALA A 146;VAL A 109;GLY A 135;ILE A 134;ILE A 113","None","0.96A","1muiA-4qnnA:undetectable","1muiA-4qnnA:18.57"],["1MUI_B_AB1B100_1","4rxt","Agrobacterium tumefaciens","SUGAR ABC TRANSPORTER","PF13407(Peripla_BP_4)",5,"GLY A 269;ALA A 270;GLY A 255;ILE A 254;ILE A 242","None","0.98A","1muiA-4rxtA:undetectable","1muiA-4rxtA:17.99"],["1MUI_B_AB1B100_1","4tqk","Agrocybe aegerita","LECTIN 2","PF13517(VCBS)",5,"ASP A 345;GLY A 350;ASP A 290;VAL A 343;GLY A 371","None","0.88A","1muiA-4tqkA:undetectable","1muiA-4tqkA:15.05"],["1MUI_B_AB1B100_1","4x9n","Mycoplasma pneumoniae","L-ALPHA-GLYCEROPHOSPHATE OXIDASE","PF01266(DAO)",5,"GLY A 344;ASP A 207;VAL A 358;GLY A  12;ILE A 357","None;None;None;FAD A 401 (-3.2A);None","0.98A","1muiA-4x9nA:undetectable","1muiA-4x9nA:14.77"],["1MUI_B_AB1B100_1","4xr9","Micromonospora echinospora","CALS8","PF00984(UDPG_MGDP_dh);PF03720(UDPG_MGDP_dh_C);PF03721(UDPG_MGDP_dh_N)",5,"ASP A 248;VAL A 249;GLY A 452;ILE A 451;ILE A 250","None","0.95A","1muiA-4xr9A:undetectable","1muiA-4xr9A:13.83"],["1MUI_B_AB1B100_1","4ydf","Primate T-lymphotropic virus 1","HTLV-1 PROTEASE","PF00077(RVP)",7,"ASP A  32;GLY A  34;ALA A  35;ASP A  36;VAL A  39;GLY A  58;ILE A 100","4B1 A 201 (-2.9A);4B1 A 201 ( 4.6A);4B1 A 201 (-3.6A);4B1 A 201 (-4.4A);None;4B1 A 201 (-3.4A);4B1 A 201 (-4.8A)","0.53A","1muiA-4ydfA:13.1","1muiA-4ydfA:31.30"],["1MUI_B_AB1B100_1","4yzg","Arabidopsis thaliana","PROTEIN PHOSPHATASE 2C 57","PF00481(PP2C)",5,"ASP A 238;GLY A 160;GLY A 179;ILE A 178;ILE A 230","None","0.96A","1muiA-4yzgA:undetectable","1muiA-4yzgA:17.17"],["1MUI_B_AB1B100_1","5b18","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP)",5,"GLY A  27;ALA A  28;ASP A  29;ASP A  30;ILE A  84","None","0.28A","1muiA-5b18A:17.9","1muiA-5b18A:76.77"],["1MUI_B_AB1B100_1","5b18","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP)",5,"GLY A  27;ALA A  28;ASP A  29;GLY A  49;ILE A  84","None","0.69A","1muiA-5b18A:17.9","1muiA-5b18A:76.77"],["1MUI_B_AB1B100_1","5g5g","Escherichia coli","PUTATIVE XANTHINE DEHYDROGENASE YAGT IRON-SULFUR-BINDING SUBUNIT","PF00111(Fer2);PF01799(Fer2_2)",5,"GLY A 211;ALA A 212;ASP A 154;GLY A 159;ILE A 216","None;None;None;FES A 230 (-4.2A);None","0.85A","1muiA-5g5gA:undetectable","1muiA-5g5gA:24.86"],["1MUI_B_AB1B100_1","5i3s","Staphylococcus aureus","INOSITOL MONOPHOSPHATASE FAMILY PROTEIN","PF00459(Inositol_P)",5,"GLY A 131;ALA A 132;VAL A 189;GLY A 135;ILE A 215","None","0.90A","1muiA-5i3sA:undetectable","1muiA-5i3sA:18.32"],["1MUI_B_AB1B100_1","5j1k","Helicobacter pylori","TOXR-ACTIVATED GENE (TAGE)","PF01551(Peptidase_M23)",5,"GLY A 230;ALA A 180;VAL A 186;GLY A 234;ILE A 227","None","0.89A","1muiA-5j1kA:undetectable","1muiA-5j1kA:18.88"],["1MUI_B_AB1B100_1","5j1l","Helicobacter pylori","TOXR-ACTIVATED GENE (TAGE)","PF01551(Peptidase_M23)",5,"GLY B 230;ALA B 180;VAL B 186;GLY B 234;ILE B 227","None","0.87A","1muiA-5j1lB:undetectable","1muiA-5j1lB:19.15"],["1MUI_B_AB1B100_1","5jxk","Porphyromonas endodontalis","ASP\/GLU-SPECIFIC DIPEPTIDYL-PEPTIDASE","PF10459(Peptidase_S46)",5,"GLY A 583;ALA A 594;VAL A 263;ILE A 689;ILE A 581","None","0.90A","1muiA-5jxkA:undetectable","1muiA-5jxkA:8.46"],["1MUI_B_AB1B100_1","5t2z","Human immunodeficiency virus 1","PROTEASE","PF00077(RVP)",10,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;VAL A  32;GLY A  49;ILE A  50;PRO A  81;ILE A  84","None","0.50A","1muiA-5t2zA:19.8","1muiA-5t2zA:80.81"],["1MUI_B_AB1B100_1","5w1a","Drosophila melanogaster","MYOSIN HEAVY CHAIN, MUSCLE","no annotation",6,"GLY A 259;ALA A 260;ASP A 261;VAL A 219;GLY A 457;ILE A 456","None","1.31A","1muiA-5w1aA:undetectable","1muiA-5w1aA:19.42"],["1MUI_B_AB1B100_1","5x1n","Sphingobium sp. SYK-6","VANILLATE\/3-O-METHYLGALLATE O-DEMETHYLASE","PF01571(GCV_T);PF08669(GCV_T_C)",6,"GLY A 168;ALA A 171;ASP A 173;GLY A 238;ILE A 240;ILE A 166","None","1.25A","1muiA-5x1nA:undetectable","1muiA-5x1nA:15.67"],["1MUI_B_AB1B100_1","5y6q","Methylobacillus sp. KY4400","ALDEHYDE OXIDASE SMALL SUBUNIT","no annotation",5,"GLY A 141;ALA A 142;ASP A  99;GLY A 104;ILE A 146","None;None;None;FES A 202 (-4.1A);None","0.97A","1muiA-5y6qA:undetectable","1muiA-5y6qA:19.59"],["1MUI_B_AB1B100_1","6f8l","-","-","no annotation",5,"ASP G 401;GLY G 403;ALA G 404;VAL G 429;GLY G 425","None","0.90A","1muiA-6f8lG:undetectable","1muiA-6f8lG:undetectable"],["1MUI_B_AB1B100_1","6fiv","Feline immunodeficiency virus","RETROPEPSIN","PF00077(RVP)",5,"ASP A  30;GLY A  32;ALA A  33;ASP A  34;GLY A  58","3TL A 201 (-3.5A);3TL A 201 (-3.4A);3TL A 201 (-4.0A);3TL A 201 (-3.9A);3TL A 201 (-3.4A)","0.30A","1muiA-6fivA:15.7","1muiA-6fivA:29.91"],["1MUI_B_AB1B100_1","6upj","Human immunodeficiency virus 2","HIV-2 PROTEASE","PF00077(RVP)",6,"ASP A  25;ALA A  28;ASP A  29;GLY A  48;PRO A  81;ILE A  84","NIU A 100 (-2.8A);NIU A 100 (-3.6A);None;None;None;None","0.91A","1muiA-6upjA:18.1","1muiA-6upjA:48.48"],["1MUI_B_AB1B100_1","6upj","Human immunodeficiency virus 2","HIV-2 PROTEASE","PF00077(RVP)",8,"ASP A  25;GLY A  27;ALA A  28;ASP A  29;ASP A  30;GLY A  49;PRO A  81;ILE A  84","NIU A 100 (-2.8A);NIU A 100 (-4.5A);NIU A 100 (-3.6A);None;None;NIU A 100 ( 3.8A);None;None","0.62A","1muiA-6upjA:18.1","1muiA-6upjA:48.48"],["1MUI_B_AB1B100_1","6upj","Human immunodeficiency virus 2","HIV-2 PROTEASE","PF00077(RVP)",8,"ASP A  25;GLY A  27;ASP A  29;ASP A  30;GLY A  49;ILE A  50;PRO A  81;ILE A  84","NIU A 100 (-2.8A);NIU A 100 (-4.5A);None;None;NIU A 100 ( 3.8A);NIU A 100 (-3.9A);None;None","0.78A","1muiA-6upjA:18.1","1muiA-6upjA:48.48"]]