SIMILAR PATTERNS OF AMINO ACIDS FOR 1MT1_C_AG2C7004_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a0f | GLUTATHIONES-TRANSFERASE (Escherichiacoli) |
PF00043(GST_C)PF13409(GST_N_2) | 4 | ALA A 68LEU A 62GLU A 65LEU A 3 | NoneNoneGTS A 203 (-3.1A)None | 1.00A | 1mt1D-1a0fA:0.01mt1E-1a0fA:undetectable | 1mt1D-1a0fA:19.211mt1E-1a0fA:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cnt | CILIARY NEUROTROPHICFACTOR (Homo sapiens) |
PF01110(CNTF) | 4 | LEU 1 130GLU 1 125LEU 1 16LEU 1 176 | None | 0.73A | 1mt1D-1cnt1:undetectable1mt1E-1cnt1:undetectable | 1mt1D-1cnt1:20.151mt1E-1cnt1:15.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fkm | PROTEIN (GYP1P) (Saccharomycescerevisiae) |
PF00566(RabGAP-TBC) | 4 | ALA A 581LEU A 488LEU A 454LEU A 602 | None | 0.98A | 1mt1D-1fkmA:undetectable1mt1E-1fkmA:undetectable | 1mt1D-1fkmA:13.281mt1E-1fkmA:10.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fp2 | ISOFLAVONEO-METHYLTRANSFERASE (Medicago sativa) |
PF00891(Methyltransf_2)PF08100(Dimerisation) | 4 | ALA A 167LEU A 123LEU A 154LEU A 314 | NoneHMO A2000 (-3.8A)NoneNone | 0.89A | 1mt1D-1fp2A:undetectable1mt1E-1fp2A:undetectable | 1mt1D-1fp2A:13.071mt1E-1fp2A:9.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gyt | CYTOSOLAMINOPEPTIDASE (Escherichiacoli) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 4 | ALA A 409LEU A 402LEU A 466LEU A 267 | None | 0.90A | 1mt1D-1gytA:0.01mt1E-1gytA:0.0 | 1mt1D-1gytA:12.031mt1E-1gytA:9.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j9a | OLIGORIBONUCLEASE (Haemophilusinfluenzae) |
PF00929(RNase_T) | 4 | ALA A 44GLU A 45LEU A 164LEU A 49 | None | 1.00A | 1mt1D-1j9aA:0.01mt1E-1j9aA:undetectable | 1mt1D-1j9aA:23.531mt1E-1j9aA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lpe | APOLIPOPROTEIN E3 (Homo sapiens) |
PF01442(Apolipoprotein) | 4 | LEU A 52GLU A 121LEU A 133LEU A 43 | None | 0.84A | 1mt1D-1lpeA:undetectable1mt1E-1lpeA:undetectable | 1mt1D-1lpeA:20.001mt1E-1lpeA:13.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lql | OSMOTICAL INDUCIBLEPROTEIN C LIKEFAMILY (Mycoplasmapneumoniae) |
PF02566(OsmC) | 4 | ALA A 121LEU A 46GLU A 53LEU A 95 | None | 0.77A | 1mt1D-1lqlA:0.01mt1E-1lqlA:undetectable | 1mt1D-1lqlA:20.251mt1E-1lqlA:13.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n21 | (+)-BORNYLDIPHOSPHATE SYNTHASE (Salviaofficinalis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | LEU A 118GLU A 277LEU A 89LEU A 96 | None | 0.99A | 1mt1D-1n21A:undetectable1mt1E-1n21A:undetectable | 1mt1D-1n21A:11.661mt1E-1n21A:8.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t1e | KUMAMOLISIN (Bacillus sp.MN-32) |
PF00082(Peptidase_S8)PF09286(Pro-kuma_activ) | 4 | ALA A 76LEU A 54LEU A 343ASP A 339 | None | 0.91A | 1mt1D-1t1eA:0.01mt1E-1t1eA:0.0 | 1mt1D-1t1eA:10.261mt1E-1t1eA:7.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 1 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | ALA A 238LEU A 354GLU A 239LEU A 26 | None | 0.93A | 1mt1D-1tqyA:0.31mt1E-1tqyA:0.0 | 1mt1D-1tqyA:14.151mt1E-1tqyA:9.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u5u | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
no annotation | 4 | ALA A 162LEU A 180ASP A 115LEU A 106 | None | 0.90A | 1mt1D-1u5uA:0.01mt1E-1u5uA:0.0 | 1mt1D-1u5uA:13.371mt1E-1u5uA:9.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1upx | HYDROXYLAMINEREDUCTASE (Desulfovibriodesulfuricans) |
PF03063(Prismane) | 4 | ALA A 100LEU A 108LEU A 51LEU A 44 | None | 1.00A | 1mt1D-1upxA:0.01mt1E-1upxA:undetectable | 1mt1D-1upxA:13.091mt1E-1upxA:7.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vi6 | 30S RIBOSOMALPROTEIN S2P (Archaeoglobusfulgidus) |
PF00318(Ribosomal_S2) | 4 | ALA A 59GLU A 177LEU A 9LEU A 51 | None | 1.00A | 1mt1D-1vi6A:undetectable1mt1E-1vi6A:undetectable | 1mt1D-1vi6A:19.311mt1E-1vi6A:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdt | ELONGATION FACTOR GHOMOLOG (Thermusthermophilus) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03764(EFG_IV)PF14492(EFG_II) | 4 | ALA A 104LEU A 78LEU A 264LEU A 272 | None | 0.89A | 1mt1D-1wdtA:undetectable1mt1E-1wdtA:undetectable | 1mt1D-1wdtA:10.021mt1E-1wdtA:5.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ywf | PHOSPHOTYROSINEPROTEIN PHOSPHATASEPTPB (Mycobacteriumtuberculosis) |
PF13350(Y_phosphatase3) | 4 | ALA A 16LEU A 275LEU A 175LEU A 150 | None | 0.89A | 1mt1D-1ywfA:undetectable1mt1E-1ywfA:undetectable | 1mt1D-1ywfA:17.331mt1E-1ywfA:13.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zan | FAB AD11 HEAVY CHAIN (Rattusnorvegicus) |
PF07654(C1-set)PF07686(V-set) | 4 | ALA H 88LEU H 82LEU H 20LEU H 67 | None | 0.97A | 1mt1D-1zanH:undetectable1mt1E-1zanH:0.0 | 1mt1D-1zanH:17.761mt1E-1zanH:10.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2agj | YVO FAB, HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | ALA H 93LEU H 87LEU H 20LEU H 69 | None | 0.88A | 1mt1D-2agjH:undetectable1mt1E-2agjH:0.0 | 1mt1D-2agjH:18.141mt1E-2agjH:12.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eta | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY VMEMBER 2 (Rattusnorvegicus) |
PF12796(Ank_2) | 4 | ALA A 167LEU A 140ASP A 143LEU A 106 | None | 0.87A | 1mt1D-2etaA:undetectable1mt1E-2etaA:undetectable | 1mt1D-2etaA:17.721mt1E-2etaA:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f37 | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY VMEMBER 2 (Homo sapiens) |
PF12796(Ank_2) | 4 | ALA A 166LEU A 139ASP A 142LEU A 105 | None | 0.88A | 1mt1D-2f37A:undetectable1mt1E-2f37A:undetectable | 1mt1D-2f37A:17.651mt1E-2f37A:17.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g0t | CONSERVEDHYPOTHETICAL PROTEIN (Thermotogamaritima) |
PF07755(DUF1611)PF17396(DUF1611_N) | 4 | ALA A 26LEU A 114LEU A 92LEU A 99 | None | 0.99A | 1mt1D-2g0tA:undetectable1mt1E-2g0tA:0.0 | 1mt1D-2g0tA:17.571mt1E-2g0tA:8.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hjs | USG-1 PROTEINHOMOLOG (Pseudomonasaeruginosa) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | ALA A 122LEU A 69LEU A 126LEU A 330 | None | 0.79A | 1mt1D-2hjsA:undetectable1mt1E-2hjsA:undetectable | 1mt1D-2hjsA:16.121mt1E-2hjsA:11.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nsa | TRIGGER FACTOR (Thermotogamaritima) |
PF05698(Trigger_C) | 4 | ALA A 391LEU A 384GLU A 359LEU A 363 | SO4 A 415 (-3.8A)NoneSO4 A 415 (-3.0A)None | 0.84A | 1mt1D-2nsaA:undetectable1mt1E-2nsaA:undetectable | 1mt1D-2nsaA:22.221mt1E-2nsaA:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nw0 | PLYB (unidentifiedphage) |
PF01183(Glyco_hydro_25) | 4 | ALA A 69LEU A 110GLU A 72LEU A 120 | None | 0.95A | 1mt1D-2nw0A:undetectable1mt1E-2nw0A:undetectable | 1mt1D-2nw0A:19.891mt1E-2nw0A:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p35 | TRANS-ACONITATE2-METHYLTRANSFERASE (Agrobacteriumfabrum) |
PF13489(Methyltransf_23) | 4 | ALA A 126LEU A 28LEU A 119ASP A 94 | None | 0.87A | 1mt1D-2p35A:undetectable1mt1E-2p35A:undetectable | 1mt1D-2p35A:16.991mt1E-2p35A:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p8u | HYDROXYMETHYLGLUTARYL-COA SYNTHASE,CYTOPLASMIC (Homo sapiens) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 4 | ALA A 185LEU A 179LEU A 386LEU A 357 | None | 0.97A | 1mt1D-2p8uA:0.41mt1E-2p8uA:undetectable | 1mt1D-2p8uA:13.221mt1E-2p8uA:8.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q80 | GERANYLGERANYLPYROPHOSPHATESYNTHETASE (Homo sapiens) |
PF00348(polyprenyl_synt) | 4 | LEU A 62GLU A 54LEU A 20LEU A 13 | None | 0.85A | 1mt1D-2q80A:undetectable1mt1E-2q80A:undetectable | 1mt1D-2q80A:16.271mt1E-2q80A:10.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wfh | SLIT HOMOLOG 2PROTEIN C-PRODUCT (Homo sapiens) |
PF01462(LRRNT)PF01463(LRRCT)PF13855(LRR_8) | 4 | LEU A 779GLU A 772LEU A 748LEU A 784 | None | 0.83A | 1mt1D-2wfhA:undetectable1mt1E-2wfhA:undetectable | 1mt1D-2wfhA:18.811mt1E-2wfhA:13.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y0e | UDP-GLUCOSEDEHYDROGENASE (Burkholderiacepacia) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 4 | ALA A 394LEU A 385LEU A 328LEU A 345 | None | 0.93A | 1mt1D-2y0eA:undetectable1mt1E-2y0eA:undetectable | 1mt1D-2y0eA:12.761mt1E-2y0eA:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ykf | PROBABLE SENSORHISTIDINE KINASEPDTAS (Mycobacteriumtuberculosis) |
PF12282(H_kinase_N) | 4 | ALA A 197LEU A 260LEU A 215LEU A 222 | None | 1.00A | 1mt1D-2ykfA:undetectable1mt1E-2ykfA:undetectable | 1mt1D-2ykfA:17.571mt1E-2ykfA:12.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zat | DEHYDROGENASE/REDUCTASE SDR FAMILYMEMBER 4 (Sus scrofa) |
PF13561(adh_short_C2) | 4 | ALA A 231LEU A 28GLU A 228LEU A 63 | None | 0.77A | 1mt1D-2zatA:undetectable1mt1E-2zatA:undetectable | 1mt1D-2zatA:16.411mt1E-2zatA:11.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bg2 | DGTPTRIPHOSPHOHYDROLASE (Leeuwenhoekiellablandensis) |
PF01966(HD) | 4 | ALA A 111LEU A 29ASP A 104LEU A 8 | None | 0.98A | 1mt1D-3bg2A:undetectable1mt1E-3bg2A:undetectable | 1mt1D-3bg2A:13.961mt1E-3bg2A:9.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cwv | DNA GYRASE, BSUBUNIT, TRUNCATED (Myxococcusxanthus) |
PF00204(DNA_gyraseB) | 4 | ALA A 274LEU A 342LEU A 242LEU A 352 | None | 0.91A | 1mt1D-3cwvA:undetectable1mt1E-3cwvA:undetectable | 1mt1D-3cwvA:14.841mt1E-3cwvA:9.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3da8 | PROBABLE5'-PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASEPURN (Mycobacteriumtuberculosis) |
PF00551(Formyl_trans_N) | 4 | ALA A 193LEU A 187LEU A 92LEU A 148 | None | 0.75A | 1mt1D-3da8A:undetectable1mt1E-3da8A:undetectable | 1mt1D-3da8A:20.091mt1E-3da8A:12.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3djb | HYDROLASE, HD FAMILY (Bacillusthuringiensis) |
PF01966(HD) | 4 | GLU A 192LEU A 124ASP A 120LEU A 117 | None | 0.89A | 1mt1D-3djbA:undetectable1mt1E-3djbA:undetectable | 1mt1D-3djbA:19.631mt1E-3djbA:11.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | ALA A 162LEU A 180ASP A 115LEU A 106 | None | 0.79A | 1mt1D-3dy5A:undetectable1mt1E-3dy5A:undetectable | 1mt1D-3dy5A:8.601mt1E-3dy5A:4.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dyj | TALIN-1 (Mus musculus) |
no annotation | 4 | ALA A1981LEU A2033ASP A2029LEU A2026 | None | 0.63A | 1mt1D-3dyjA:undetectable1mt1E-3dyjA:undetectable | 1mt1D-3dyjA:16.171mt1E-3dyjA:11.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e05 | PRECORRIN-6YC5,15-METHYLTRANSFERASE(DECARBOXYLATING) (Geobactermetallireducens) |
no annotation | 4 | ALA A 307LEU A 314GLU A 309LEU A 302 | None | 0.98A | 1mt1D-3e05A:undetectable1mt1E-3e05A:undetectable | 1mt1D-3e05A:20.111mt1E-3e05A:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ejn | SUSD HOMOLOG (Bacteroidesfragilis) |
PF12771(SusD-like_2) | 4 | ALA A 46LEU A 106LEU A 187LEU A 157 | None | 0.83A | 1mt1D-3ejnA:undetectable1mt1E-3ejnA:undetectable | 1mt1D-3ejnA:12.921mt1E-3ejnA:7.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fyq | CG6831-PA (TALIN) (Drosophilamelanogaster) |
no annotation | 4 | ALA A1990LEU A2042ASP A2038LEU A2035 | None | 0.67A | 1mt1D-3fyqA:undetectable1mt1E-3fyqA:undetectable | 1mt1D-3fyqA:19.801mt1E-3fyqA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gu0 | TRIGGER FACTOR (Thermotogamaritima) |
PF05697(Trigger_N)PF05698(Trigger_C) | 4 | ALA A 391LEU A 384GLU A 359LEU A 363 | None | 0.74A | 1mt1D-3gu0A:undetectable1mt1E-3gu0A:undetectable | 1mt1D-3gu0A:15.661mt1E-3gu0A:8.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7l | ENDOGLUCANASE (Vibrioparahaemolyticus) |
PF00759(Glyco_hydro_9)PF02927(CelD_N) | 4 | ALA A 47LEU A 27GLU A 49LEU A 3 | None | 0.98A | 1mt1D-3h7lA:undetectable1mt1E-3h7lA:undetectable | 1mt1D-3h7lA:11.131mt1E-3h7lA:6.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmc | PUTATIVE PROPHAGELAMBDABA04, GLYCOSYLHYDROLASE, FAMILY 25 (Bacillusanthracis) |
PF01183(Glyco_hydro_25) | 4 | ALA A 72LEU A 113GLU A 75LEU A 123 | None | 0.96A | 1mt1D-3hmcA:undetectable1mt1E-3hmcA:undetectable | 1mt1D-3hmcA:19.131mt1E-3hmcA:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic1 | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Haemophilusinfluenzae) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | ALA A 112LEU A 105GLU A 113LEU A 51 | None | 1.00A | 1mt1D-3ic1A:undetectable1mt1E-3ic1A:undetectable | 1mt1D-3ic1A:15.831mt1E-3ic1A:8.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ico | 6-PHOSPHOGLUCONOLACTONASE (Mycobacteriumtuberculosis) |
PF01182(Glucosamine_iso) | 4 | ALA A 25LEU A 144LEU A 53LEU A 67 | None | 0.95A | 1mt1D-3icoA:undetectable1mt1E-3icoA:undetectable | 1mt1D-3icoA:18.491mt1E-3icoA:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jru | PROBABLE CYTOSOLAMINOPEPTIDASE (Xanthomonasoryzae) |
no annotation | 4 | ALA B 401LEU B 394LEU B 458LEU B 259 | None | 0.81A | 1mt1D-3jruB:undetectable1mt1E-3jruB:undetectable | 1mt1D-3jruB:12.791mt1E-3jruB:7.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obk | DELTA-AMINOLEVULINICACID DEHYDRATASE (Toxoplasmagondii) |
PF00490(ALAD) | 4 | ALA A 121LEU A 114LEU A 92LEU A 70 | NoneNoneNoneEDO A 385 (-4.3A) | 1.00A | 1mt1D-3obkA:undetectable1mt1E-3obkA:undetectable | 1mt1D-3obkA:17.051mt1E-3obkA:9.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obk | DELTA-AMINOLEVULINICACID DEHYDRATASE (Toxoplasmagondii) |
PF00490(ALAD) | 4 | ALA A 121LEU A 115LEU A 131LEU A 50 | None | 0.76A | 1mt1D-3obkA:undetectable1mt1E-3obkA:undetectable | 1mt1D-3obkA:17.051mt1E-3obkA:9.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8c | PROBABLE PROTEINBRICK1WISKOTT-ALDRICHSYNDROME PROTEINFAMILY MEMBER 1 (Homo sapiens) |
PF02205(WH2)no annotation | 4 | ALA E 66GLU E 65LEU D 76LEU D 83 | None | 0.91A | 1mt1D-3p8cE:undetectable1mt1E-3p8cE:undetectable | 1mt1D-3p8cE:24.551mt1E-3p8cE:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pei | CYTOSOLAMINOPEPTIDASE (Francisellatularensis) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 4 | ALA A 389LEU A 382LEU A 447LEU A 247 | EDO A 510 (-4.0A)EDO A 502 (-4.1A)NoneNone | 0.87A | 1mt1D-3peiA:undetectable1mt1E-3peiA:undetectable | 1mt1D-3peiA:13.541mt1E-3peiA:8.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3skv | SSFX3 (Streptomycessp. SF2575) |
PF13472(Lipase_GDSL_2) | 4 | ALA A 192GLU A 196LEU A 361LEU A 313 | None | 0.80A | 1mt1D-3skvA:undetectable1mt1E-3skvA:undetectable | 1mt1D-3skvA:13.871mt1E-3skvA:12.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tni | CYCLIN-T1 (Homo sapiens) |
PF00134(Cyclin_N) | 4 | ALA B 91GLU B 95LEU B 57LEU B 182 | None | 0.98A | 1mt1D-3tniB:undetectable1mt1E-3tniB:undetectable | 1mt1D-3tniB:16.601mt1E-3tniB:10.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u7r | NADPH-DEPENDENT FMNREDUCTASE (Paracoccusdenitrificans) |
PF03358(FMN_red) | 4 | ALA A 143LEU A 72LEU A 21LEU A 28 | None | 0.83A | 1mt1D-3u7rA:undetectable1mt1E-3u7rA:undetectable | 1mt1D-3u7rA:22.781mt1E-3u7rA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x1o | ROQUIN-1 (Homo sapiens) |
no annotation | 4 | ALA A 252LEU A 204GLU A 282LEU A 307 | None | 0.90A | 1mt1D-3x1oA:undetectable1mt1E-3x1oA:undetectable | 1mt1D-3x1oA:18.841mt1E-3x1oA:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cp6 | CHOLINE BINDINGPROTEIN PCPA (Streptococcuspneumoniae) |
PF13306(LRR_5) | 4 | ALA A 335LEU A 342LEU A 324LEU A 368 | None | 0.98A | 1mt1D-4cp6A:undetectable1mt1E-4cp6A:undetectable | 1mt1D-4cp6A:11.091mt1E-4cp6A:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h2k | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Haemophilusinfluenzae) |
PF01546(Peptidase_M20) | 4 | ALA A 112LEU A 105GLU A 113LEU A 51 | None | 1.02A | 1mt1D-4h2kA:undetectable1mt1E-4h2kA:undetectable | 1mt1D-4h2kA:20.451mt1E-4h2kA:12.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hj3 | LOV PROTEIN (Rhodobactersphaeroides) |
PF13426(PAS_9) | 4 | ALA A 167LEU A 161LEU A 98LEU A 81 | None | 0.71A | 1mt1D-4hj3A:undetectable1mt1E-4hj3A:undetectable | 1mt1D-4hj3A:22.991mt1E-4hj3A:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwv | PECTATE LYASE/AMBALLERGEN (Acidovoraxcitrulli) |
PF00544(Pec_lyase_C) | 4 | ALA A 393GLU A 394LEU A 478LEU A 484 | None | 0.92A | 1mt1D-4hwvA:undetectable1mt1E-4hwvA:undetectable | 1mt1D-4hwvA:12.631mt1E-4hwvA:9.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4igl | YENB (Yersiniaentomophaga) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 4 | ALA A 460LEU A 533LEU A 501LEU A 525 | None | 0.96A | 1mt1D-4iglA:undetectable1mt1E-4iglA:undetectable | 1mt1D-4iglA:5.241mt1E-4iglA:3.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdq | SLR1964 PROTEIN (Synechocystissp. PCC 6803) |
no annotation | 4 | ALA A 89LEU A 95GLU A 91LEU A 20 | None | 0.86A | 1mt1D-4jdqA:undetectable1mt1E-4jdqA:undetectable | 1mt1D-4jdqA:20.831mt1E-4jdqA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jw1 | EFFECTOR PROTEIN B (Legionellapneumophila) |
no annotation | 4 | LEU A 147GLU A 298LEU A 242LEU A 65 | None | 0.79A | 1mt1D-4jw1A:undetectable1mt1E-4jw1A:undetectable | 1mt1D-4jw1A:11.671mt1E-4jw1A:5.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ler | PUTATIVE OUTERMEMBRANE PROTEIN,PROBABLY INVOLVED INNUTRIENT BINDING (Bacteroidesvulgatus) |
PF12771(SusD-like_2) | 4 | ALA A 50LEU A 109LEU A 190LEU A 160 | None | 0.95A | 1mt1D-4lerA:undetectable1mt1E-4lerA:undetectable | 1mt1D-4lerA:13.621mt1E-4lerA:10.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mnr | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Eggerthellalenta) |
PF00905(Transpeptidase) | 4 | ALA A 231LEU A 245GLU A 200LEU A 193 | None | 0.95A | 1mt1D-4mnrA:undetectable1mt1E-4mnrA:undetectable | 1mt1D-4mnrA:14.101mt1E-4mnrA:9.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n8g | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Chromohalobactersalexigens) |
PF03480(DctP) | 4 | ALA A 144LEU A 245GLU A 145LEU A 31 | None | 0.93A | 1mt1D-4n8gA:undetectable1mt1E-4n8gA:undetectable | 1mt1D-4n8gA:15.251mt1E-4n8gA:10.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ofz | TREHALOSE-PHOSPHATASE (Brugia malayi) |
no annotation | 4 | ALA A 267LEU A 100ASP A 96LEU A 92 | None | 0.93A | 1mt1D-4ofzA:undetectable1mt1E-4ofzA:undetectable | 1mt1D-4ofzA:12.651mt1E-4ofzA:7.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qik | ROQUIN-1 (Homo sapiens) |
no annotation | 4 | ALA A 252LEU A 204GLU A 282LEU A 307 | None | 0.92A | 1mt1D-4qikA:undetectable1mt1E-4qikA:undetectable | 1mt1D-4qikA:16.041mt1E-4qikA:11.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4txa | ROQUIN-1 (Mus musculus) |
PF13445(zf-RING_UBOX) | 4 | ALA A 252LEU A 204GLU A 282LEU A 307 | None | 1.00A | 1mt1D-4txaA:undetectable1mt1E-4txaA:undetectable | 1mt1D-4txaA:12.291mt1E-4txaA:10.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uqg | DNA POLYMERASE (Geobacillusstearothermophilus) |
PF00476(DNA_pol_A) | 4 | LEU A 474GLU A 464LEU A 401LEU A 394 | None | 0.99A | 1mt1D-4uqgA:1.81mt1E-4uqgA:undetectable | 1mt1D-4uqgA:10.541mt1E-4uqgA:6.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z31 | ROQUIN-2 (Homo sapiens) |
no annotation | 4 | ALA A 249LEU A 201GLU A 279LEU A 304 | None | 0.88A | 1mt1D-4z31A:undetectable1mt1E-4z31A:undetectable | 1mt1D-4z31A:13.611mt1E-4z31A:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z8z | UNCHARACTERIZEDPROTEIN (Ruminiclostridiumthermocellum) |
no annotation | 4 | ALA A 168LEU A 71GLU A 167LEU A 43 | None | 0.86A | 1mt1D-4z8zA:undetectable1mt1E-4z8zA:undetectable | 1mt1D-4z8zA:15.481mt1E-4z8zA:13.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zlc | ROQUIN-2 (Homo sapiens) |
no annotation | 4 | ALA A 249LEU A 201GLU A 279LEU A 304 | None | 0.88A | 1mt1D-4zlcA:undetectable1mt1E-4zlcA:undetectable | 1mt1D-4zlcA:21.121mt1E-4zlcA:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c05 | PUTATIVEGAMMA-TERPINENESYNTHASE (Thymus vulgaris) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | LEU A 195GLU A 223LEU A 243LEU A 236 | LEU A 195 ( 0.6A)GLU A 223 ( 0.5A)LEU A 243 ( 0.5A)LEU A 236 ( 0.6A) | 1.00A | 1mt1D-5c05A:undetectable1mt1E-5c05A:undetectable | 1mt1D-5c05A:11.271mt1E-5c05A:6.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cx8 | LIPOPROTEIN RAGB (Porphyromonasgingivalis) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 4 | LEU A 408GLU A 383LEU A 432LEU A 424 | None | 1.01A | 1mt1D-5cx8A:undetectable1mt1E-5cx8A:undetectable | 1mt1D-5cx8A:11.851mt1E-5cx8A:9.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ddb | MENIN (Homo sapiens) |
PF05053(Menin) | 4 | ALA A 25GLU A 26LEU A 36LEU A 83 | None | 0.92A | 1mt1D-5ddbA:undetectable1mt1E-5ddbA:undetectable | 1mt1D-5ddbA:12.811mt1E-5ddbA:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ddb | MENIN (Homo sapiens) |
PF05053(Menin) | 4 | ALA A 25LEU A 13GLU A 26LEU A 36 | None | 1.02A | 1mt1D-5ddbA:undetectable1mt1E-5ddbA:undetectable | 1mt1D-5ddbA:12.811mt1E-5ddbA:7.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f5f | ROQUIN-1 (Mus musculus) |
no annotation | 4 | ALA A 252LEU A 204GLU A 282LEU A 307 | None | 0.98A | 1mt1D-5f5fA:undetectable1mt1E-5f5fA:undetectable | 1mt1D-5f5fA:18.041mt1E-5f5fA:12.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f96 | HEAVY CHAIN OFANTIBODY CH235.12 (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | ALA H 88LEU H 82LEU H 20LEU H 67 | None | 0.90A | 1mt1D-5f96H:undetectable1mt1E-5f96H:undetectable | 1mt1D-5f96H:16.671mt1E-5f96H:14.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fyr | PHOSPHOINOSITOL-SPECIFIC PHOSPHOLIPASE C (Pseudomonas sp.) |
PF16670(PI-PLC-C1) | 4 | ALA A 96GLU A 95LEU A 139LEU A 118 | None | 0.91A | 1mt1D-5fyrA:undetectable1mt1E-5fyrA:undetectable | 1mt1D-5fyrA:16.611mt1E-5fyrA:11.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5goo | ALKALINE INVERTASE (Nostoc sp. PCC7120) |
PF12899(Glyco_hydro_100) | 4 | ALA A 207LEU A 168LEU A 232LEU A 225 | None | 0.81A | 1mt1D-5gooA:undetectable1mt1E-5gooA:undetectable | 1mt1D-5gooA:13.111mt1E-5gooA:7.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw5 | T-COMPLEX PROTEIN 1SUBUNIT THETA (Saccharomycescerevisiae) |
PF00118(Cpn60_TCP1) | 4 | ALA q 527LEU q 521LEU q 139LEU q 430 | None | 0.95A | 1mt1D-5gw5q:undetectable1mt1E-5gw5q:undetectable | 1mt1D-5gw5q:13.881mt1E-5gw5q:7.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5v | FLAGELLARHOOK-ASSOCIATEDPROTEIN 2 (Escherichiacoli) |
PF02465(FliD_N)PF07195(FliD_C) | 4 | ALA A 156LEU A 201LEU A 178LEU A 193 | None | 0.93A | 1mt1D-5h5vA:undetectable1mt1E-5h5vA:undetectable | 1mt1D-5h5vA:11.411mt1E-5h5vA:9.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5w | FLAGELLARHOOK-ASSOCIATEDPROTEIN 2 (Escherichiacoli) |
PF07195(FliD_C)PF07196(Flagellin_IN) | 4 | ALA A 156LEU A 201LEU A 178LEU A 193 | None | 0.92A | 1mt1D-5h5wA:undetectable1mt1E-5h5wA:undetectable | 1mt1D-5h5wA:15.921mt1E-5h5wA:14.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ifg | ANTITOXIN HIGAMRNA INTERFERASEHIGB (Escherichiacoli) |
PF01381(HTH_3)PF09907(HigB_toxin) | 4 | ALA A 8LEU B 34ASP B 38LEU B 41 | None | 0.95A | 1mt1D-5ifgA:undetectable1mt1E-5ifgA:undetectable | 1mt1D-5ifgA:24.191mt1E-5ifgA:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iki | CYTOCHROME P450(MEG) (Bacillusmegaterium) |
PF00067(p450) | 4 | LEU A 154GLU A 116LEU A 363LEU A 146 | None | 0.92A | 1mt1D-5ikiA:undetectable1mt1E-5ikiA:undetectable | 1mt1D-5ikiA:13.301mt1E-5ikiA:9.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jj7 | ADENOSINEMONOPHOSPHATE-PROTEIN TRANSFERASE FICDHOMOLOG (Caenorhabditiselegans) |
PF02661(Fic) | 4 | ALA A 414LEU A 402LEU A 444LEU A 452 | None | 0.91A | 1mt1D-5jj7A:undetectable1mt1E-5jj7A:undetectable | 1mt1D-5jj7A:15.191mt1E-5jj7A:10.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jr3 | CARMINOMYCIN4-O-METHYLTRANSFERASE DNRK (Streptomycespeucetius) |
PF00891(Methyltransf_2) | 4 | ALA A 35LEU A 54LEU A 78LEU A 45 | None | 0.99A | 1mt1D-5jr3A:undetectable1mt1E-5jr3A:undetectable | 1mt1D-5jr3A:15.521mt1E-5jr3A:7.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lfd | ALLANTOIN RACEMASE (Pseudomonasfluorescens) |
no annotation | 4 | ALA A 41GLU A 42LEU A 147LEU A 116 | None | 0.92A | 1mt1D-5lfdA:undetectable1mt1E-5lfdA:undetectable | 1mt1D-5lfdA:18.991mt1E-5lfdA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m59 | PRE-MRNA SPLICINGHELICASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | ALA A1411LEU A1478GLU A1412LEU A1448 | None | 0.86A | 1mt1D-5m59A:undetectable1mt1E-5m59A:undetectable | 1mt1D-5m59A:5.221mt1E-5m59A:2.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mmh | HTH-TYPETRANSCRIPTIONALACTIVATOR AMPR (Pseudomonasaeruginosa) |
PF03466(LysR_substrate) | 4 | ALA A 100LEU A 113LEU A 285LEU A 96 | None | 0.97A | 1mt1D-5mmhA:undetectable1mt1E-5mmhA:undetectable | 1mt1D-5mmhA:15.601mt1E-5mmhA:12.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u2g | PENICILLIN-BINDINGPROTEIN 1A (Haemophilusinfluenzae) |
PF00905(Transpeptidase)PF00912(Transgly)PF17092(PCB_OB) | 4 | ALA A 81LEU A 188LEU A 164LEU A 169 | None | 1.01A | 1mt1D-5u2gA:undetectable1mt1E-5u2gA:undetectable | 1mt1D-5u2gA:8.731mt1E-5u2gA:6.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wi9 | - (-) |
no annotation | 4 | LEU A 463LEU A 141ASP A 137LEU A 134 | None | 0.99A | 1mt1D-5wi9A:undetectable1mt1E-5wi9A:undetectable | 1mt1D-5wi9A:undetectable1mt1E-5wi9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wwt | PUTATIVEMETHYLTRANSFERASENSUN6 (Homo sapiens) |
PF01189(Methyltr_RsmB-F) | 4 | ALA A 411LEU A 388GLU A 381LEU A 421 | None | 0.82A | 1mt1D-5wwtA:undetectable1mt1E-5wwtA:undetectable | 1mt1D-5wwtA:13.921mt1E-5wwtA:7.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wy4 | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
no annotation | 4 | ALA A 270LEU A 201LEU A 255LEU A 193 | None | 0.93A | 1mt1D-5wy4A:undetectable1mt1E-5wy4A:undetectable | 1mt1D-5wy4A:18.971mt1E-5wy4A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y9s | VV2_1132 (Vibriovulnificus) |
no annotation | 4 | LEU A 61GLU A 73LEU A 14LEU A 43 | None | 0.92A | 1mt1D-5y9sA:undetectable1mt1E-5y9sA:undetectable | 1mt1D-5y9sA:21.051mt1E-5y9sA:27.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yqw | PEPTIDE ABCTRANSPORTER,PERIPLASMICPEPTIDE-BINDINGPROTEIN (Vibrio harveyi) |
no annotation | 4 | LEU A 196GLU A 181LEU A 191LEU A 520 | None | 0.89A | 1mt1D-5yqwA:undetectable1mt1E-5yqwA:undetectable | 1mt1D-5yqwA:18.521mt1E-5yqwA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bwm | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY VMEMBER 2 (Oryctolaguscuniculus) |
no annotation | 4 | ALA A 165LEU A 138ASP A 141LEU A 104 | None | 0.86A | 1mt1D-6bwmA:undetectable1mt1E-6bwmA:undetectable | 1mt1D-6bwmA:17.241mt1E-6bwmA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6by9 | HISTONE-LYSINEN-METHYLTRANSFERASEEHMT1 (Homo sapiens) |
no annotation | 4 | ALA A 927LEU A 910GLU A 923LEU A 957 | None | 1.00A | 1mt1D-6by9A:undetectable1mt1E-6by9A:undetectable | 1mt1D-6by9A:28.161mt1E-6by9A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC1DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC2 (Saccharomycescerevisiae) |
no annotation | 4 | LEU A 473GLU B1066LEU B1062LEU B1079 | None | 0.59A | 1mt1D-6f42A:undetectable1mt1E-6f42A:undetectable | 1mt1D-6f42A:20.721mt1E-6f42A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ffv | - (-) |
no annotation | 4 | ALA A 172LEU A 3LEU A 116LEU A 108 | BNG A 307 ( 3.7A)NonePG4 A 305 (-4.5A)PG4 A 304 ( 4.6A) | 1.00A | 1mt1D-6ffvA:undetectable1mt1E-6ffvA:undetectable | 1mt1D-6ffvA:undetectable1mt1E-6ffvA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fyd | PUTATIVEFAD-DEPENDENTOXYGENASE ENCM (Streptomycesmaritimus) |
no annotation | 4 | ALA A 232LEU A 332LEU A 248LEU A 341 | None | 0.90A | 1mt1D-6fydA:undetectable1mt1E-6fydA:undetectable | 1mt1D-6fydA:16.811mt1E-6fydA:18.75 |