SIMILAR PATTERNS OF AMINO ACIDS FOR 1MRJ_A_ADNA300

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1abr ABRIN-A

(Abrus
precatorius) 		PF00161
(RIP) 		5 GLY A 111
TYR A 113
ILE A 159
GLU A 164
ARG A 167
 None
 0.39A 1mrjA-1abrA:
34.1		 1mrjA-1abrA:
36.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1aha ALPHA-MOMORCHARIN

(Momordica
charantia) 		PF00161
(RIP) 		6 ILE A  71
GLY A 109
TYR A 111
ILE A 155
GLU A 160
ARG A 163
 ADE  A 339 (-3.9A)
ADE  A 339 (-4.1A)
ADE  A 339 ( 3.6A)
ADE  A 339 (-4.1A)
ADE  A 339 (-4.5A)
ADE  A 339 ( 2.9A)
 0.28A 1mrjA-1ahaA:
41.4		 1mrjA-1ahaA:
65.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1aha ALPHA-MOMORCHARIN

(Momordica
charantia) 		PF00161
(RIP) 		4 TYR A  70
ILE A  71
TYR A 111
ILE A 155
 ADE  A 339 ( 3.8A)
ADE  A 339 (-3.9A)
ADE  A 339 ( 3.6A)
ADE  A 339 (-4.1A)
 0.86A 1mrjA-1ahaA:
41.4		 1mrjA-1ahaA:
65.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1apa POKEWEED ANTIVIRAL
PROTEIN

(Phytolacca
americana) 		PF00161
(RIP) 		5 TYR A 128
ILE A 175
SER A 179
GLU A 180
ARG A 183
 None
 0.48A 1mrjA-1apaA:
30.2		 1mrjA-1apaA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1avq LAMBDA EXONUCLEASE

(Escherichia
virus Lambda) 		PF09588
(YqaJ) 		4 ILE A  41
ILE A 202
SER A 198
GLU A 201
 None
None
ACT  A 228 (-3.6A)
None
 0.69A 1mrjA-1avqA:
undetectable		 1mrjA-1avqA:
21.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bry BRYODIN I

(Bryonia dioica) 		PF00161
(RIP) 		6 ILE Y  71
GLY Y 109
TYR Y 111
ILE Y 155
GLU Y 160
ARG Y 163
 None
 0.27A 1mrjA-1bryY:
43.2		 1mrjA-1bryY:
86.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ce7 PROTEIN
(RIBOSOME-INACTIVATI
NG PROTEIN TYPE II)

(Viscum album) 		PF00161
(RIP) 		5 GLY A 109
TYR A 111
ILE A 155
SER A 159
GLU A 160
 None
 0.53A 1mrjA-1ce7A:
31.6		 1mrjA-1ce7A:
35.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ce7 PROTEIN
(RIBOSOME-INACTIVATI
NG PROTEIN TYPE II)

(Viscum album) 		PF00161
(RIP) 		4 TYR A  75
TYR A 111
SER A 159
GLU A 160
 None
 0.85A 1mrjA-1ce7A:
31.6		 1mrjA-1ce7A:
35.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ce7 PROTEIN
(RIBOSOME-INACTIVATI
NG PROTEIN TYPE II)

(Viscum album) 		PF00161
(RIP) 		5 TYR A 111
ILE A 155
SER A 159
GLU A 160
ARG A 163
 None
 0.44A 1mrjA-1ce7A:
31.6		 1mrjA-1ce7A:
35.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1cf5 PROTEIN
(BETA-MOMORCHARIN)

(Momordica
charantia) 		PF00161
(RIP) 		5 GLY A 107
TYR A 109
ILE A 153
GLU A 158
ARG A 161
 None
 0.52A 1mrjA-1cf5A:
39.0		 1mrjA-1cf5A:
61.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hwn EBULIN

(Sambucus ebulus) 		PF00161
(RIP) 		5 GLY A 114
TYR A 116
ILE A 158
GLU A 163
ARG A 166
 None
 0.76A 1mrjA-1hwnA:
33.1		 1mrjA-1hwnA:
38.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lpc DIANTHIN 30

(Dianthus
caryophyllus) 		PF00161
(RIP) 		4 TYR A 121
ILE A 172
GLU A 177
ARG A 180
 CMP  A 901 (-4.3A)
CMP  A 901 (-4.1A)
CMP  A 901 (-3.9A)
CMP  A 901 (-3.0A)
 0.20A 1mrjA-1lpcA:
27.6		 1mrjA-1lpcA:
22.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nio B-LUFFIN

(Luffa
aegyptiaca) 		PF00161
(RIP) 		6 ILE A  72
GLY A 109
TYR A 111
ILE A 155
GLU A 160
ARG A 163
 None
 0.27A 1mrjA-1nioA:
40.6		 1mrjA-1nioA:
60.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nnh ASPARAGINYL-TRNA
SYNTHETASE-RELATED
PEPTIDE

(Pyrococcus
furiosus) 		PF00152
(tRNA-synt_2) 		4 ILE A  77
GLY A 219
SER A  75
ARG A  99
 None
 0.86A 1mrjA-1nnhA:
undetectable		 1mrjA-1nnhA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcj POKEWEED ANTIVIRAL
PROTEIN

(Phytolacca
americana) 		PF00161
(RIP) 		4 TYR A 123
ILE A 171
GLU A 176
ARG A 179
 APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 ( 3.6A)
APT  A 901 (-3.0A)
 0.33A 1mrjA-1qcjA:
30.4		 1mrjA-1qcjA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcj POKEWEED ANTIVIRAL
PROTEIN

(Phytolacca
americana) 		PF00161
(RIP) 		4 TYR A 123
ILE A 171
SER A 175
ARG A 179
 APT  A 901 (-4.7A)
APT  A 901 (-3.7A)
APT  A 901 (-1.7A)
APT  A 901 (-3.0A)
 0.65A 1mrjA-1qcjA:
30.4		 1mrjA-1qcjA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qi7 PROTEIN
(N-GLYCOSIDASE)

(Saponaria
officinalis) 		PF00161
(RIP) 		4 TYR A 120
ILE A 171
GLU A 176
ARG A 179
 None
 0.27A 1mrjA-1qi7A:
27.6		 1mrjA-1qi7A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qyc PHENYLCOUMARAN
BENZYLIC ETHER
REDUCTASE PT1

(Pinus taeda) 		PF05368
(NmrA) 		4 ILE A 146
TYR A 150
ILE A 141
GLU A 142
 None
 0.83A 1mrjA-1qycA:
undetectable		 1mrjA-1qycA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N) 		4 ILE B 222
GLY B 246
TYR B 248
GLU B 101
 None
 0.87A 1mrjA-1skyB:
undetectable		 1mrjA-1skyB:
20.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tcs TRICHOSANTHIN

(Trichosanthes
kirilowii) 		PF00161
(RIP) 		7 ILE A  71
GLY A 109
TYR A 111
ILE A 155
SER A 159
GLU A 160
ARG A 163
 NDP  A 280 (-4.5A)
NDP  A 280 (-3.9A)
NDP  A 280 ( 3.7A)
NDP  A 280 (-3.9A)
NDP  A 280 (-3.3A)
NDP  A 280 ( 2.7A)
NDP  A 280 ( 2.6A)
 0.11A 1mrjA-1tcsA:
43.9		 1mrjA-1tcsA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1un1 XYLOGLUCAN
ENDOTRANSGLYCOSYLASE

(Populus tremula) 		PF00722
(Glyco_hydro_16)
PF06955
(XET_C) 		4 TYR A  51
GLY A  49
TYR A  15
ILE A 169
 None
 0.90A 1mrjA-1un1A:
undetectable		 1mrjA-1un1A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vya NUCLEOSIDE
DIPHOSPHATE KINASE

(Zea mays) 		PF00334
(NDK) 		4 ILE A 127
GLY A 134
SER A   3
GLU A  76
 None
 0.90A 1mrjA-1vyaA:
undetectable		 1mrjA-1vyaA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyd HYPOTHETICAL
ASPARTYL-TRNA
SYNTHETASE

(Sulfurisphaera
tokodaii) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 ILE A 294
GLY A 297
ILE A 284
GLU A 285
 None
 0.83A 1mrjA-1wydA:
undetectable		 1mrjA-1wydA:
20.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4

(Viscum album) 		PF00161
(RIP) 		4 GLY A 108
ILE A 154
SER A 158
GLU A 159
 None
None
None
P6C  A1001 ( 4.4A)
 0.56A 1mrjA-1yf8A:
31.4		 1mrjA-1yf8A:
35.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4

(Viscum album) 		PF00161
(RIP) 		4 ILE A 154
SER A 158
GLU A 159
ARG A 162
 None
None
P6C  A1001 ( 4.4A)
P6C  A1001 (-2.6A)
 0.48A 1mrjA-1yf8A:
31.4		 1mrjA-1yf8A:
35.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4

(Viscum album) 		PF00161
(RIP) 		4 TYR A  75
ILE A 154
SER A 158
GLU A 159
 P6C  A1001 (-4.6A)
None
None
P6C  A1001 ( 4.4A)
 0.88A 1mrjA-1yf8A:
31.4		 1mrjA-1yf8A:
35.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yqd SINAPYL ALCOHOL
DEHYDROGENASE

(Populus
tremuloides) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ILE A 303
GLY A  97
TYR A 148
GLU A 114
 NAP  A 500 (-4.3A)
None
None
None
 0.82A 1mrjA-1yqdA:
undetectable		 1mrjA-1yqdA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bvm TOXIN B

(Clostridioides
difficile) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 TYR A 407
ILE A 403
ILE A 271
SER A 251
 None
 0.91A 1mrjA-2bvmA:
undetectable		 1mrjA-2bvmA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4m GLYCOGEN
PHOSPHORYLASE

(Corynebacterium
callunae) 		PF00343
(Phosphorylase) 		4 ILE A 558
GLY A 560
ILE A 610
SER A 614
 None
 0.87A 1mrjA-2c4mA:
undetectable		 1mrjA-2c4mA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d9s CBL E3 UBIQUITIN
PROTEIN LIGASE

(Mus musculus) 		PF00627
(UBA) 		4 TYR A  23
ILE A  26
ILE A  13
GLU A  14
 None
 0.65A 1mrjA-2d9sA:
undetectable		 1mrjA-2d9sA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii) 		PF00440
(TetR_N)
PF13977
(TetR_C_6) 		4 GLY A  23
ILE A  21
SER A 107
GLU A 111
 None
 0.87A 1mrjA-2g3bA:
undetectable		 1mrjA-2g3bA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5x RIBOSOME-INACTIVATIN
G PROTEIN

(Silene
chalcedonica) 		PF00161
(RIP) 		5 TYR A  69
TYR A 119
ILE A 165
GLU A 170
ARG A 173
 None
 0.64A 1mrjA-2g5xA:
24.9		 1mrjA-2g5xA:
27.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h88 SUCCINATE
DEHYDROGENASE
FLAVOPROTEIN SUBUNIT

(Gallus gallus) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 TYR A 287
ILE A 306
GLU A 307
ARG A 312
 None
 0.65A 1mrjA-2h88A:
undetectable		 1mrjA-2h88A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hne L-FUCONATE
DEHYDRATASE

(Xanthomonas
campestris) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 323
GLY A 300
ILE A 337
GLU A 333
 None
 0.83A 1mrjA-2hneA:
undetectable		 1mrjA-2hneA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hpi DNA POLYMERASE III
ALPHA SUBUNIT

(Thermus
aquaticus) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		4 ILE A 127
GLY A 120
ILE A 131
GLU A 130
 None
 0.84A 1mrjA-2hpiA:
undetectable		 1mrjA-2hpiA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipc PREPROTEIN
TRANSLOCASE SECA
SUBUNIT

(Thermus
thermophilus) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 ILE A 154
GLY A 152
SER A 158
GLU A 162
 None
 0.90A 1mrjA-2ipcA:
undetectable		 1mrjA-2ipcA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ob1 LEUCINE CARBOXYL
METHYLTRANSFERASE 1

(Saccharomyces
cerevisiae) 		PF04072
(LCM) 		4 GLY A  84
TYR A  79
ILE A 294
GLU A 298
 None
 0.79A 1mrjA-2ob1A:
undetectable		 1mrjA-2ob1A:
22.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2oqa LUFFACULIN 1

(Luffa
acutangula) 		PF00161
(RIP) 		6 ILE A  71
GLY A 108
TYR A 110
ILE A 154
GLU A 159
ARG A 162
 None
 0.31A 1mrjA-2oqaA:
39.9		 1mrjA-2oqaA:
62.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pqi RIBOSOME-INACTIVATIN
G PROTEIN 3

(Zea mays) 		PF00161
(RIP) 		5 TYR A  94
GLY A 128
TYR A 130
GLU A 207
ARG A 210
 None
 0.48A 1mrjA-2pqiA:
24.5		 1mrjA-2pqiA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q8w POKEWEED ANTIVIRAL
PROTEIN

(Phytolacca
acinosa) 		PF00161
(RIP) 		5 GLY A 120
TYR A 122
ILE A 170
GLU A 175
ARG A 178
 None
 0.25A 1mrjA-2q8wA:
30.5		 1mrjA-2q8wA:
28.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qes RIBOSOME-INACTIVATIN
G PROTEIN PD-L4

(Phytolacca
dioica) 		PF00161
(RIP) 		4 TYR A 122
ILE A 170
GLU A 175
ARG A 178
 ADE  A 501 (-3.7A)
ADE  A 501 (-4.0A)
ADE  A 501 ( 4.7A)
ADE  A 501 (-2.9A)
 0.18A 1mrjA-2qesA:
30.6		 1mrjA-2qesA:
30.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qes RIBOSOME-INACTIVATIN
G PROTEIN PD-L4

(Phytolacca
dioica) 		PF00161
(RIP) 		4 TYR A 122
ILE A 170
SER A 174
GLU A 175
 ADE  A 501 (-3.7A)
ADE  A 501 (-4.0A)
ADE  A 501 (-3.6A)
ADE  A 501 ( 4.7A)
 0.67A 1mrjA-2qesA:
30.6		 1mrjA-2qesA:
30.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vdc GLUTAMATE SYNTHASE
[NADPH] LARGE CHAIN

(Azospirillum
brasilense) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		4 GLY A 361
ILE A 380
GLU A 381
ARG A 402
 None
 0.88A 1mrjA-2vdcA:
undetectable		 1mrjA-2vdcA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III

(Cinnamomum
camphora) 		PF00161
(RIP)
PF00652
(Ricin_B_lectin) 		5 GLY A 113
TYR A 115
ILE A 162
GLU A 167
ARG A 170
 None
 0.16A 1mrjA-2vlcA:
30.9		 1mrjA-2vlcA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vlc TYPE 2
RIBOSOME-INACTIVATIN
G PROTEIN CINNAMOMIN
III

(Cinnamomum
camphora) 		PF00161
(RIP)
PF00652
(Ricin_B_lectin) 		4 TYR A  75
TYR A 115
GLU A 167
ARG A 170
 None
 0.89A 1mrjA-2vlcA:
30.9		 1mrjA-2vlcA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vwk DNA POLYMERASE

(Thermococcus
gorgonarius) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 ILE A 693
TYR A 673
ILE A 666
GLU A 664
 None
 0.88A 1mrjA-2vwkA:
undetectable		 1mrjA-2vwkA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbm RIBOSOME MATURATION
PROTEIN SDO1 HOMOLOG

(Methanothermobacter
thermautotrophicus) 		PF01172
(SBDS)
PF09377
(SBDS_C) 		4 TYR A 180
ILE A 183
ILE A 189
GLU A 192
 None
None
None
GOL  A1235 (-3.5A)
 0.81A 1mrjA-2wbmA:
undetectable		 1mrjA-2wbmA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu5 SUCCINATE
DEHYDROGENASE
FLAVOPROTEIN SUBUNIT

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 TYR A 276
ILE A 295
GLU A 296
ARG A 301
 None
 0.62A 1mrjA-2wu5A:
undetectable		 1mrjA-2wu5A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN

(Prochlorococcus
marinus) 		PF00142
(Fer4_NifH) 		4 ILE A 238
GLY A 257
ILE A 248
SER A 241
 ADP  A1300 (-3.6A)
None
None
None
 0.92A 1mrjA-2ynmA:
undetectable		 1mrjA-2ynmA:
22.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zr1 AGGLUTININ-1 CHAIN A

(Abrus
precatorius) 		PF00161
(RIP) 		5 GLY A 110
TYR A 112
ILE A 158
GLU A 163
ARG A 166
 None
 0.27A 1mrjA-2zr1A:
33.7		 1mrjA-2zr1A:
35.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3bwh CUCURMOSIN

(Cucurbita
moschata) 		PF00161
(RIP) 		7 ILE A  71
GLY A 107
TYR A 109
ILE A 153
SER A 157
GLU A 158
ARG A 161
 None
EDO  A 253 (-4.5A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 ( 4.6A)
EDO  A 253 (-2.9A)
 0.28A 1mrjA-3bwhA:
40.8		 1mrjA-3bwhA:
61.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3bwh CUCURMOSIN

(Cucurbita
moschata) 		PF00161
(RIP) 		4 TYR A  70
TYR A 109
SER A 157
GLU A 158
 EDO  A 253 ( 4.5A)
EDO  A 253 ( 4.1A)
EDO  A 253 ( 4.6A)
EDO  A 253 ( 4.6A)
 0.83A 1mrjA-3bwhA:
40.8		 1mrjA-3bwhA:
61.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctk RRNA N-GLYCOSIDASE

(Bougainvillea
spectabilis) 		PF00161
(RIP) 		6 GLY A 112
TYR A 114
ILE A 160
SER A 164
GLU A 165
ARG A 168
 None
 0.22A 1mrjA-3ctkA:
32.6		 1mrjA-3ctkA:
29.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dkh LACCASE-1

(Melanocarpus
albomyces) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ILE A  97
GLY A 437
SER A 135
ARG A 272
 None
 0.84A 1mrjA-3dkhA:
undetectable		 1mrjA-3dkhA:
18.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3h5k RIBOSOME-INACTIVATIN
G PROTEIN
PD-L1/PD-L2

(Phytolacca
dioica) 		PF00161
(RIP) 		5 TYR A 122
ILE A 170
SER A 174
GLU A 175
ARG A 178
 EDO  A 264 (-3.5A)
EDO  A 264 (-4.0A)
None
None
None
 0.23A 1mrjA-3h5kA:
30.7		 1mrjA-3h5kA:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdo HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Geobacter
metallireducens) 		PF00155
(Aminotran_1_2) 		4 TYR A 109
GLY A 118
ILE A 107
GLU A 106
 None
 0.82A 1mrjA-3hdoA:
undetectable		 1mrjA-3hdoA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hig AMILORIDE-SENSITIVE
AMINE OXIDASE

(Homo sapiens) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 GLY A 375
TYR A 638
GLU A 113
ARG A  98
 None
 0.91A 1mrjA-3higA:
undetectable		 1mrjA-3higA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi) 		PF01182
(Glucosamine_iso) 		4 TYR A   9
ILE A  12
GLY A  47
ILE A 202
 None
 0.90A 1mrjA-3hn6A:
undetectable		 1mrjA-3hn6A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iv3 TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 2

(Streptococcus
mutans) 		PF01791
(DeoC) 		5 TYR A 145
ILE A 146
TYR A  91
ILE A 149
GLU A 152
 EDO  A 336 (-4.1A)
None
None
None
None
 1.20A 1mrjA-3iv3A:
undetectable		 1mrjA-3iv3A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jrk TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 2

(Streptococcus
pyogenes) 		PF01791
(DeoC) 		5 TYR A 141
ILE A 142
TYR A  87
ILE A 145
GLU A 148
 None
 1.24A 1mrjA-3jrkA:
undetectable		 1mrjA-3jrkA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kao TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE

(Staphylococcus
aureus) 		PF01791
(DeoC) 		5 TYR A 145
ILE A 146
TYR A  91
ILE A 149
GLU A 152
 None
 1.24A 1mrjA-3kaoA:
undetectable		 1mrjA-3kaoA:
23.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN

(Suregada
multiflora) 		PF00161
(RIP) 		7 TYR A  74
GLY A 111
TYR A 113
ILE A 161
SER A 165
GLU A 166
ARG A 169
 ADE  A 800 (-3.5A)
ADE  A 800 (-4.1A)
ADE  A 800 (-3.5A)
ADE  A 800 (-4.0A)
ADE  A 800 ( 3.7A)
ADE  A 800 ( 4.5A)
ADE  A 800 (-2.7A)
 0.25A 1mrjA-3ku0A:
33.7		 1mrjA-3ku0A:
37.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN

(Iris x
hollandica) 		PF00161
(RIP) 		5 GLY A 106
TYR A 108
ILE A 156
GLU A 161
ARG A 164
 GOL  A 284 ( 4.9A)
GOL  A 281 (-4.4A)
None
None
GOL  A 284 (-3.1A)
 0.45A 1mrjA-3mvgA:
32.4		 1mrjA-3mvgA:
32.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mvg RIBOSOME
INACTIVATING TYPE 1
PROTEIN

(Iris x
hollandica) 		PF00161
(RIP) 		5 GLY A 106
TYR A 108
ILE A 156
SER A 160
GLU A 161
 GOL  A 284 ( 4.9A)
GOL  A 281 (-4.4A)
None
None
None
 0.28A 1mrjA-3mvgA:
32.4		 1mrjA-3mvgA:
32.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1

(Streptococcus
pyogenes) 		PF01791
(DeoC) 		5 TYR A 144
ILE A 145
TYR A  90
ILE A 148
GLU A 151
 None
 1.22A 1mrjA-3myoA:
undetectable		 1mrjA-3myoA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8t ASNS-LIKE
ASPARAGINYL-TRNA
SYNTHETASE RELATED
PROTEIN

(Pyrococcus
abyssi) 		PF00152
(tRNA-synt_2) 		4 ILE A  77
GLY A 219
SER A  75
ARG A  99
 None
 0.86A 1mrjA-3p8tA:
undetectable		 1mrjA-3p8tA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppc 5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE

(Candida
albicans) 		PF01717
(Meth_synt_2)
PF08267
(Meth_synt_1) 		4 ILE A 168
TYR A 238
ILE A 217
GLU A 219
 None
 0.86A 1mrjA-3ppcA:
undetectable		 1mrjA-3ppcA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rv6 ISOCHORISMATE
SYNTHASE/ISOCHORISMA
TE-PYRUVATE LYASE
MBTI

(Mycobacterium
tuberculosis) 		PF00425
(Chorismate_bind) 		5 ILE A 365
GLY A 370
TYR A 119
SER A 304
GLU A 308
 RVA  A 454 (-4.0A)
None
None
None
None
 1.47A 1mrjA-3rv6A:
undetectable		 1mrjA-3rv6A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swe UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Haemophilus
influenzae) 		PF00275
(EPSP_synthase) 		4 ILE A 397
ILE A 404
GLU A 405
ARG A 417
 None
 0.89A 1mrjA-3sweA:
undetectable		 1mrjA-3sweA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tfo PUTATIVE
3-OXOACYL-(ACYL-CARR
IER-PROTEIN)
REDUCTASE

(Sinorhizobium
meliloti) 		PF00106
(adh_short) 		4 ILE A  41
GLY A  14
ILE A  44
GLU A  47
 None
 0.84A 1mrjA-3tfoA:
undetectable		 1mrjA-3tfoA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vrb FLAVOPROTEIN SUBUNIT
OF COMPLEX II

(Ascaris suum) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 TYR A 310
ILE A 329
GLU A 330
ARG A 335
 None
 0.72A 1mrjA-3vrbA:
undetectable		 1mrjA-3vrbA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zq4 RIBONUCLEASE J 1

(Bacillus
subtilis) 		PF00753
(Lactamase_B)
PF07521
(RMMBL) 		4 GLY A 102
ILE A 265
SER A 261
GLU A 264
 None
 0.85A 1mrjA-3zq4A:
undetectable		 1mrjA-3zq4A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amc GLUCANSUCRASE

(Lactobacillus
reuteri) 		PF01473
(CW_binding_1)
PF02324
(Glyco_hydro_70) 		4 GLY A1209
ILE A1140
SER A1136
ARG A1130
 None
 0.79A 1mrjA-4amcA:
undetectable		 1mrjA-4amcA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ap5 GDP-FUCOSE PROTEIN
O-FUCOSYLTRANSFERASE
2

(Homo sapiens) 		PF10250
(O-FucT) 		4 ILE A 427
GLY A 230
TYR A 228
GLU A 395
 None
 0.85A 1mrjA-4ap5A:
undetectable		 1mrjA-4ap5A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4em6 GLUCOSE-6-PHOSPHATE
ISOMERASE

(Brucella
melitensis) 		no annotation 4 ILE D 146
GLY D 136
ILE D 133
ARG D 257
 None
 0.90A 1mrjA-4em6D:
undetectable		 1mrjA-4em6D:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fbh PROTEIN SYNTHESIS
INHIBITOR I

(Hordeum vulgare) 		PF00161
(RIP) 		4 GLY A 116
TYR A 118
GLU A 175
ARG A 178
 AMP  A 301 ( 3.8A)
None
AMP  A 301 ( 4.8A)
AMP  A 301 (-3.0A)
 0.54A 1mrjA-4fbhA:
24.7		 1mrjA-4fbhA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnv HEPARINASE III
PROTEIN, HEPARITIN
SULFATE LYASE

(Bacteroides
thetaiotaomicron) 		PF07940
(Hepar_II_III)
PF16889
(Hepar_II_III_N) 		4 ILE A 514
GLY A 567
TYR A 655
ILE A 575
 None
 0.92A 1mrjA-4fnvA:
undetectable		 1mrjA-4fnvA:
15.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4imv RICIN

(Ricinus
communis) 		PF00161
(RIP) 		4 GLY A 121
TYR A 123
ILE A 172
SER A 176
 None
 0.40A 1mrjA-4imvA:
18.9		 1mrjA-4imvA:
30.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ixu ARGINASE-2,
MITOCHONDRIAL

(Homo sapiens) 		PF00491
(Arginase) 		4 ILE A 184
GLY A  93
ILE A 124
SER A 128
 None
 0.80A 1mrjA-4ixuA:
undetectable		 1mrjA-4ixuA:
22.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN

(Viscum album) 		PF00161
(RIP) 		5 GLY A 113
ILE A 160
SER A 164
GLU A 165
ARG A 168
 None
H35  A 305 ( 4.5A)
None
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 0.47A 1mrjA-4jkxA:
32.3		 1mrjA-4jkxA:
37.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4juu EPIMERASE

(Xanthomonas
campestris) 		PF05544
(Pro_racemase) 		4 ILE A  77
GLY A  86
GLU A  36
ARG A  39
 None
 0.92A 1mrjA-4juuA:
undetectable		 1mrjA-4juuA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kwg ALDEHYDE
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00171
(Aldedh) 		4 GLY A 225
ILE A 249
SER A 246
GLU A 248
 None
 0.87A 1mrjA-4kwgA:
undetectable		 1mrjA-4kwgA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ttp DEPHOSPHO-COA KINASE

(Legionella
pneumophila) 		PF01121
(CoaE) 		4 TYR A 127
ILE A 116
ILE A 102
GLU A 103
 None
 0.84A 1mrjA-4ttpA:
undetectable		 1mrjA-4ttpA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uaq PROTEIN TRANSLOCASE
SUBUNIT SECA 2

(Mycobacterium
tuberculosis) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 ILE A 164
GLY A 162
SER A 168
GLU A 172
 None
 0.66A 1mrjA-4uaqA:
undetectable		 1mrjA-4uaqA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yji ARYL ACYLAMIDASE

(bacterium
CSBL00001) 		PF01425
(Amidase) 		4 GLY A 129
TYR A  53
ILE A  38
GLU A  39
 None
 0.83A 1mrjA-4yjiA:
undetectable		 1mrjA-4yjiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yry DIHYDROPYRIMIDINE
DEHYDROGENASE
SUBUNIT A

(Thermotoga
maritima) 		PF07992
(Pyr_redox_2)
PF14691
(Fer4_20) 		4 TYR B 458
ILE B 455
GLY B 427
GLU B 141
 None
 0.87A 1mrjA-4yryB:
undetectable		 1mrjA-4yryB:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ao5 C-TYPE MANNOSE
RECEPTOR 2

(Homo sapiens) 		PF00040
(fn2)
PF00059
(Lectin_C) 		4 ILE A 338
TYR A 249
ILE A 285
GLU A 281
 None
 0.82A 1mrjA-5ao5A:
undetectable		 1mrjA-5ao5A:
18.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ddz RICIN

(Ricinus
communis) 		PF00161
(RIP) 		5 GLY A 121
TYR A 123
ILE A 172
GLU A 177
ARG A 180
 None
 0.43A 1mrjA-5ddzA:
34.4		 1mrjA-5ddzA:
35.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ddz RICIN

(Ricinus
communis) 		PF00161
(RIP) 		5 GLY A 121
TYR A 123
ILE A 172
SER A 176
GLU A 177
 None
 0.25A 1mrjA-5ddzA:
34.4		 1mrjA-5ddzA:
35.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ex6 CYTOCHROME P450

(Streptomyces
toyocaensis) 		no annotation 4 ILE C  73
GLY C  75
ILE C 292
GLU C 293
 None
 0.75A 1mrjA-5ex6C:
undetectable		 1mrjA-5ex6C:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fp1 TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Acinetobacter
baumannii) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 ILE A 539
GLY A 523
GLU A 568
ARG A  85
 None
 0.70A 1mrjA-5fp1A:
undetectable		 1mrjA-5fp1A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3

(Homo sapiens) 		PF04153
(NOT2_3_5) 		4 TYR C 744
ILE C 715
GLU C 720
ARG C 708
 None
 0.90A 1mrjA-5fu6C:
undetectable		 1mrjA-5fu6C:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g3p FORMAMIDASE

(Bacillus cereus) 		PF00795
(CN_hydrolase) 		4 TYR A  98
ILE A 119
GLY A 154
ILE A 127
 None
 0.90A 1mrjA-5g3pA:
undetectable		 1mrjA-5g3pA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gje LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6

(Homo sapiens) 		PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition) 		4 TYR A 348
ILE A 355
GLY A 353
ILE A 370
 None
 0.91A 1mrjA-5gjeA:
undetectable		 1mrjA-5gjeA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h6s AMIDASE

(Microbacterium
sp. HM58-2) 		PF01425
(Amidase) 		4 GLY A 140
ILE A 330
SER A 332
GLU A 333
 None
 0.77A 1mrjA-5h6sA:
undetectable		 1mrjA-5h6sA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n2i REDUCED COENZYME
F420:NADP
OXIDOREDUCTASE

(Thermobifida
fusca) 		PF03807
(F420_oxidored) 		4 GLY A  76
ILE A  47
SER A  21
GLU A  45
 None
 0.91A 1mrjA-5n2iA:
undetectable		 1mrjA-5n2iA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyh CBSA

(Xanthomonas
oryzae) 		no annotation 4 TYR A 404
ILE A 405
ILE A 437
SER A 401
 None
 0.81A 1mrjA-5xyhA:
undetectable		 1mrjA-5xyhA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bk7 ELONGATION FACTOR G

(Enterococcus
faecalis) 		no annotation 4 GLY A 259
TYR A 186
ILE A 175
GLU A 184
 None
 0.87A 1mrjA-6bk7A:
undetectable		 1mrjA-6bk7A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cey BIFUNCTIONAL AAC/APH

(Staphylococcus
aureus) 		no annotation 4 ILE A 450
TYR A 340
ILE A 351
GLU A 352
 None
 0.85A 1mrjA-6ceyA:
undetectable		 1mrjA-6ceyA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cza -

(-) 		no annotation 4 ILE A 458
GLY A 454
SER A 191
GLU A 195
 None
None
None
PO4  A 909 ( 4.2A)
 0.76A 1mrjA-6czaA:
undetectable		 1mrjA-6czaA:
undetectable