SIMILAR PATTERNS OF AMINO ACIDS FOR 1MRG_A_ADNA300_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1abr | ABRIN-A (Abrusprecatorius) |
PF00161(RIP) | 6 | GLY A 111TYR A 113ILE A 159ALA A 163GLU A 164ARG A 167 | None | 0.49A | 1mrgA-1abrA:33.6 | 1mrgA-1abrA:33.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1aha | ALPHA-MOMORCHARIN (Momordicacharantia) |
PF00161(RIP) | 8 | ILE A 71PHE A 83GLY A 109TYR A 111ILE A 155ALA A 159GLU A 160ARG A 163 | ADE A 339 (-3.9A)ADE A 339 ( 4.8A)ADE A 339 (-4.1A)ADE A 339 ( 3.6A)ADE A 339 (-4.1A)ADE A 339 ( 3.7A)ADE A 339 (-4.5A)ADE A 339 ( 2.9A) | 0.30A | 1mrgA-1ahaA:43.5 | 1mrgA-1ahaA:98.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1aha | ALPHA-MOMORCHARIN (Momordicacharantia) |
PF00161(RIP) | 5 | TYR A 70ILE A 71TYR A 111ILE A 155ALA A 159 | ADE A 339 ( 3.8A)ADE A 339 (-3.9A)ADE A 339 ( 3.6A)ADE A 339 (-4.1A)ADE A 339 ( 3.7A) | 1.06A | 1mrgA-1ahaA:43.5 | 1mrgA-1ahaA:98.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1apa | POKEWEED ANTIVIRALPROTEIN (Phytolaccaamericana) |
PF00161(RIP) | 5 | PHE A 94TYR A 128ILE A 175GLU A 180ARG A 183 | None | 0.51A | 1mrgA-1apaA:30.6 | 1mrgA-1apaA:29.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1bry | BRYODIN I (Bryonia dioica) |
PF00161(RIP) | 8 | ILE Y 71PHE Y 83GLY Y 109TYR Y 111ILE Y 155ALA Y 159GLU Y 160ARG Y 163 | None | 0.33A | 1mrgA-1bryY:41.0 | 1mrgA-1bryY:66.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1bry | BRYODIN I (Bryonia dioica) |
PF00161(RIP) | 5 | TYR Y 70TYR Y 111ILE Y 155ALA Y 159GLU Y 160 | None | 1.11A | 1mrgA-1bryY:41.0 | 1mrgA-1bryY:66.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1cf5 | PROTEIN(BETA-MOMORCHARIN) (Momordicacharantia) |
PF00161(RIP) | 7 | PHE A 83GLY A 107TYR A 109ILE A 153ALA A 157GLU A 158ARG A 161 | None | 0.49A | 1mrgA-1cf5A:38.1 | 1mrgA-1cf5A:51.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dm0 | SHIGA TOXIN ASUBUNIT (Shigelladysenteriae) |
PF00161(RIP) | 5 | PHE A 92TYR A 114ALA A 166GLU A 167ARG A 170 | None | 0.57A | 1mrgA-1dm0A:22.4 | 1mrgA-1dm0A:25.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dm0 | SHIGA TOXIN ASUBUNIT (Shigelladysenteriae) |
PF00161(RIP) | 5 | TYR A 77PHE A 95ALA A 166GLU A 167ARG A 170 | None | 1.28A | 1mrgA-1dm0A:22.4 | 1mrgA-1dm0A:25.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dq3 | ENDONUCLEASE (Pyrococcusfuriosus) |
PF09061(Stirrup)PF09062(Endonuc_subdom)PF14528(LAGLIDADG_3)PF14890(Intein_splicing) | 5 | ILE A 93PHE A 101TYR A 442ILE A 2ALA A 6 | None | 1.27A | 1mrgA-1dq3A:undetectable | 1mrgA-1dq3A:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ez4 | LACTATEDEHYDROGENASE (Lactobacilluspentosus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ILE A 94PHE A 133TYR A 83ILE A 120ALA A 96 | NoneNoneNoneNAD A1352 ( 4.9A)NAD A1352 (-3.5A) | 1.15A | 1mrgA-1ez4A:undetectable | 1mrgA-1ez4A:22.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hwn | EBULIN (Sambucus ebulus) |
PF00161(RIP) | 6 | PHE A 90GLY A 114TYR A 116ILE A 158GLU A 163ARG A 166 | None | 0.80A | 1mrgA-1hwnA:32.5 | 1mrgA-1hwnA:36.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ig8 | HEXOKINASE PII (Saccharomycescerevisiae) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 5 | TYR A 270GLY A 238TYR A 240ILE A 403ALA A 402 | None | 1.29A | 1mrgA-1ig8A:undetectable | 1mrgA-1ig8A:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l8w | VLSE1 (Borreliellaburgdorferi) |
PF00921(Lipoprotein_2) | 5 | ILE A 284PHE A 202GLY A 199ILE A 280ALA A 222 | None | 1.24A | 1mrgA-1l8wA:undetectable | 1mrgA-1l8wA:25.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lpc | DIANTHIN 30 (Dianthuscaryophyllus) |
PF00161(RIP) | 6 | PHE A 91TYR A 121ILE A 172ALA A 176GLU A 177ARG A 180 | NoneCMP A 901 (-4.3A)CMP A 901 (-4.1A)CMP A 901 ( 4.0A)CMP A 901 (-3.9A)CMP A 901 (-3.0A) | 0.53A | 1mrgA-1lpcA:27.9 | 1mrgA-1lpcA:26.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nio | B-LUFFIN (Luffaaegyptiaca) |
PF00161(RIP) | 8 | ILE A 72PHE A 84GLY A 109TYR A 111ILE A 155ALA A 159GLU A 160ARG A 163 | None | 0.23A | 1mrgA-1nioA:40.6 | 1mrgA-1nioA:69.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qcj | POKEWEED ANTIVIRALPROTEIN (Phytolaccaamericana) |
PF00161(RIP) | 5 | PHE A 90TYR A 123ILE A 171GLU A 176ARG A 179 | APT A 901 ( 4.7A)APT A 901 (-4.7A)APT A 901 (-3.7A)APT A 901 ( 3.6A)APT A 901 (-3.0A) | 0.46A | 1mrgA-1qcjA:30.6 | 1mrgA-1qcjA:31.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qi7 | PROTEIN(N-GLYCOSIDASE) (Saponariaofficinalis) |
PF00161(RIP) | 5 | PHE A 90TYR A 120ILE A 171GLU A 176ARG A 179 | None | 0.72A | 1mrgA-1qi7A:27.9 | 1mrgA-1qi7A:25.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qi7 | PROTEIN(N-GLYCOSIDASE) (Saponariaofficinalis) |
PF00161(RIP) | 5 | TYR A 72TYR A 120ALA A 175GLU A 176ARG A 179 | None | 1.14A | 1mrgA-1qi7A:27.9 | 1mrgA-1qi7A:25.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qi7 | PROTEIN(N-GLYCOSIDASE) (Saponariaofficinalis) |
PF00161(RIP) | 5 | TYR A 120ILE A 171ALA A 175GLU A 176ARG A 179 | None | 0.34A | 1mrgA-1qi7A:27.9 | 1mrgA-1qi7A:25.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r4p | SHIGA-LIKE TOXINTYPE II A SUBUNIT (Escherichiacoli) |
PF00161(RIP) | 5 | PHE A 92TYR A 114ALA A 166GLU A 167ARG A 170 | FMT A3015 ( 4.9A)FMT A3015 ( 4.1A)FMT A3015 ( 4.9A)NoneNone | 0.41A | 1mrgA-1r4pA:23.2 | 1mrgA-1r4pA:23.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tcs | TRICHOSANTHIN (Trichosantheskirilowii) |
PF00161(RIP) | 7 | ILE A 71PHE A 83GLY A 109TYR A 111ILE A 155GLU A 160ARG A 163 | NDP A 280 (-4.5A)NDP A 280 ( 4.8A)NDP A 280 (-3.9A)NDP A 280 ( 3.7A)NDP A 280 (-3.9A)NDP A 280 ( 2.7A)NDP A 280 ( 2.6A) | 0.30A | 1mrgA-1tcsA:40.5 | 1mrgA-1tcsA:63.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1woq | INORGANICPOLYPHOSPHATE/ATP-GLUCOMANNOKINASE (Arthrobactersp. KM) |
PF00480(ROK) | 5 | ILE A 15GLY A 26ILE A 28ALA A 71GLU A 70 | None | 1.11A | 1mrgA-1woqA:undetectable | 1mrgA-1woqA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y6z | HEAT SHOCK PROTEIN,PUTATIVE (Plasmodiumfalciparum) |
PF00183(HSP90) | 5 | TYR A 155ILE A 158PHE A 64ILE A 236GLU A 234 | None | 1.31A | 1mrgA-1y6zA:undetectable | 1mrgA-1y6zA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g5x | RIBOSOME-INACTIVATING PROTEIN (Silenechalcedonica) |
PF00161(RIP) | 7 | TYR A 69PHE A 88TYR A 119ILE A 165ALA A 169GLU A 170ARG A 173 | None | 0.70A | 1mrgA-2g5xA:25.6 | 1mrgA-2g5xA:29.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inp | PHENOL HYDROXYLASECOMPONENT PHL (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox) | 5 | ILE C 222GLY C 224ALA C 133GLU C 130ARG C 160 | None | 1.32A | 1mrgA-2inpC:undetectable | 1mrgA-2inpC:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inp | PHENOL HYDROXYLASECOMPONENT PHL (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox) | 5 | ILE C 222GLY C 224TYR C 227ALA C 133GLU C 130 | None | 1.27A | 1mrgA-2inpC:undetectable | 1mrgA-2inpC:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iy8 | PROTEIN PM0188 (Pasteurellamultocida) |
PF11477(PM0188) | 5 | ILE A 184TYR A 217ILE A 161ALA A 164GLU A 165 | None | 1.31A | 1mrgA-2iy8A:undetectable | 1mrgA-2iy8A:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j6l | ALDEHYDEDEHYDROGENASE FAMILY7 MEMBER A1 (Homo sapiens) |
PF00171(Aldedh) | 5 | TYR A 129ILE A 126GLY A 482ILE A 180ALA A 179 | None | 1.27A | 1mrgA-2j6lA:undetectable | 1mrgA-2j6lA:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nwi | HYPOTHETICAL PROTEIN (Archaeoglobusfulgidus) |
PF01947(DUF98) | 5 | ILE A 96TYR A 139ILE A 151ALA A 72GLU A 153 | None | 1.38A | 1mrgA-2nwiA:undetectable | 1mrgA-2nwiA:20.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oqa | LUFFACULIN 1 (Luffaacutangula) |
PF00161(RIP) | 8 | ILE A 71PHE A 83GLY A 108TYR A 110ILE A 154ALA A 158GLU A 159ARG A 162 | None | 0.32A | 1mrgA-2oqaA:39.8 | 1mrgA-2oqaA:69.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oqa | LUFFACULIN 1 (Luffaacutangula) |
PF00161(RIP) | 5 | TYR A 70TYR A 110ILE A 154ALA A 158GLU A 159 | None | 0.95A | 1mrgA-2oqaA:39.8 | 1mrgA-2oqaA:69.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ppv | UNCHARACTERIZEDPROTEIN (Staphylococcusepidermidis) |
PF01933(UPF0052) | 5 | ILE A 200ILE A 171ALA A 203GLU A 175ARG A 206 | None | 1.34A | 1mrgA-2ppvA:undetectable | 1mrgA-2ppvA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pqi | RIBOSOME-INACTIVATING PROTEIN 3 (Zea mays) |
PF00161(RIP) | 6 | TYR A 94PHE A 108GLY A 128TYR A 130GLU A 207ARG A 210 | None | 0.50A | 1mrgA-2pqiA:24.2 | 1mrgA-2pqiA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2psf | RENILLA-LUCIFERIN2-MONOOXYGENASE (Renillareniformis) |
PF00561(Abhydrolase_1) | 5 | ILE A 15GLY A 17TYR A 202GLU A 289ARG A 192 | None | 1.25A | 1mrgA-2psfA:undetectable | 1mrgA-2psfA:20.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q8w | POKEWEED ANTIVIRALPROTEIN (Phytolaccaacinosa) |
PF00161(RIP) | 6 | PHE A 89GLY A 120TYR A 122ILE A 170GLU A 175ARG A 178 | None | 0.35A | 1mrgA-2q8wA:30.7 | 1mrgA-2q8wA:30.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qes | RIBOSOME-INACTIVATING PROTEIN PD-L4 (Phytolaccadioica) |
PF00161(RIP) | 5 | PHE A 89TYR A 122ILE A 170GLU A 175ARG A 178 | ADE A 501 ( 4.9A)ADE A 501 (-3.7A)ADE A 501 (-4.0A)ADE A 501 ( 4.7A)ADE A 501 (-2.9A) | 0.28A | 1mrgA-2qesA:30.8 | 1mrgA-2qesA:30.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qw5 | XYLOSEISOMERASE-LIKE TIMBARREL (Trichormusvariabilis) |
PF01261(AP_endonuc_2) | 5 | GLY A 127TYR A 133ILE A 184GLU A 188ARG A 252 | XLS A 401 ( 4.7A)XLS A 401 ( 3.8A)XLS A 401 ( 4.3A)XLS A 401 (-3.2A)XLS A 401 ( 4.0A) | 1.01A | 1mrgA-2qw5A:undetectable | 1mrgA-2qw5A:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rg2 | CHOLOYLGLYCINEHYDROLASE (Clostridiumperfringens) |
PF02275(CBAH) | 5 | ILE A 33PHE A 67GLY A 56TYR A 317GLU A 307 | None | 1.31A | 1mrgA-2rg2A:undetectable | 1mrgA-2rg2A:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vlc | TYPE 2RIBOSOME-INACTIVATING PROTEIN CINNAMOMINIII (Cinnamomumcamphora) |
PF00161(RIP)PF00652(Ricin_B_lectin) | 6 | GLY A 113TYR A 115ILE A 162ALA A 166GLU A 167ARG A 170 | None | 0.26A | 1mrgA-2vlcA:30.6 | 1mrgA-2vlcA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vlc | TYPE 2RIBOSOME-INACTIVATING PROTEIN CINNAMOMINIII (Cinnamomumcamphora) |
PF00161(RIP)PF00652(Ricin_B_lectin) | 6 | TYR A 75TYR A 115ILE A 162ALA A 166GLU A 167ARG A 170 | None | 0.84A | 1mrgA-2vlcA:30.6 | 1mrgA-2vlcA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vob | TRYPANOTHIONESYNTHETASE (Leishmaniamajor) |
PF03738(GSP_synth)PF05257(CHAP) | 5 | ILE A 598PHE A 272ILE A 612ALA A 596GLU A 614 | None | 1.33A | 1mrgA-2vobA:undetectable | 1mrgA-2vobA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wbm | RIBOSOME MATURATIONPROTEIN SDO1 HOMOLOG (Methanothermobacterthermautotrophicus) |
PF01172(SBDS)PF09377(SBDS_C) | 5 | TYR A 180ILE A 183ILE A 189ALA A 202GLU A 192 | NoneNoneNoneNoneGOL A1235 (-3.5A) | 1.21A | 1mrgA-2wbmA:undetectable | 1mrgA-2wbmA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wj9 | INTERGENIC-REGIONPROTEIN (Escherichiacoli) |
PF03230(Antirestrict) | 5 | ILE A 152TYR A 142ILE A 113ALA A 110GLU A 109 | None | 1.27A | 1mrgA-2wj9A:undetectable | 1mrgA-2wj9A:18.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zr1 | AGGLUTININ-1 CHAIN A (Abrusprecatorius) |
PF00161(RIP) | 7 | PHE A 86GLY A 110TYR A 112ILE A 158ALA A 162GLU A 163ARG A 166 | None | 0.44A | 1mrgA-2zr1A:33.4 | 1mrgA-2zr1A:33.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zws | NEUTRAL CERAMIDASE (Pseudomonasaeruginosa) |
PF04734(Ceramidase_alk)PF17048(Ceramidse_alk_C) | 5 | ILE A 14GLY A 16ALA A 12GLU A 556ARG A 132 | None | 1.29A | 1mrgA-2zwsA:undetectable | 1mrgA-2zwsA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3all | 2-METHYL-3-HYDROXYPYRIDINE-5-CARBOXYLICACID OXYGENASE (Mesorhizobiumjaponicum) |
PF01494(FAD_binding_3) | 5 | ILE A 332TYR A 375ILE A 335GLU A 364ARG A 338 | None | 1.36A | 1mrgA-3allA:undetectable | 1mrgA-3allA:18.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3bwh | CUCURMOSIN (Cucurbitamoschata) |
PF00161(RIP) | 7 | ILE A 71PHE A 83GLY A 107TYR A 109ILE A 153GLU A 158ARG A 161 | NoneNoneEDO A 253 (-4.5A)EDO A 253 ( 4.1A)EDO A 253 ( 4.1A)EDO A 253 ( 4.6A)EDO A 253 (-2.9A) | 0.37A | 1mrgA-3bwhA:39.0 | 1mrgA-3bwhA:57.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ctk | RRNA N-GLYCOSIDASE (Bougainvilleaspectabilis) |
PF00161(RIP) | 5 | GLY A 112TYR A 114ILE A 160GLU A 165ARG A 168 | None | 0.24A | 1mrgA-3ctkA:33.0 | 1mrgA-3ctkA:29.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ehm | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF12741(SusD-like) | 5 | ILE A 104GLY A 24ILE A 119ALA A 108GLU A 116 | None | 0.98A | 1mrgA-3ehmA:undetectable | 1mrgA-3ehmA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3elu | METHYLTRANSFERASE (Wesselsbronvirus) |
PF00972(Flavi_NS5)PF01728(FtsJ) | 5 | TYR A 221ILE A 206GLY A 204ILE A 229GLU A 196 | None | 1.34A | 1mrgA-3eluA:undetectable | 1mrgA-3eluA:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fg2 | PUTATIVE RUBREDOXINREDUCTASE (Rhodopseudomonaspalustris) |
PF07992(Pyr_redox_2)PF14759(Reductase_C) | 5 | ILE P 32ILE P 75ALA P 30GLU P 73ARG P 28 | FAD P 449 ( 4.5A)NoneNoneNoneNone | 1.00A | 1mrgA-3fg2P:undetectable | 1mrgA-3fg2P:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h3j | L-LACTATEDEHYDROGENASE 1 (Staphylococcusaureus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ILE A 80PHE A 119TYR A 69ILE A 106ALA A 82 | NoneNoneNoneNAD A 500 ( 4.9A)NAD A 500 (-3.5A) | 1.28A | 1mrgA-3h3jA:undetectable | 1mrgA-3h3jA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5k | RIBOSOME-INACTIVATING PROTEINPD-L1/PD-L2 (Phytolaccadioica) |
PF00161(RIP) | 5 | PHE A 89TYR A 122ILE A 170GLU A 175ARG A 178 | NoneEDO A 264 (-3.5A)EDO A 264 (-4.0A)NoneNone | 0.32A | 1mrgA-3h5kA:30.9 | 1mrgA-3h5kA:29.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iv3 | TAGATOSE1,6-DIPHOSPHATEALDOLASE 2 (Streptococcusmutans) |
PF01791(DeoC) | 5 | TYR A 145ILE A 146TYR A 91ILE A 149GLU A 152 | EDO A 336 (-4.1A)NoneNoneNoneNone | 1.30A | 1mrgA-3iv3A:undetectable | 1mrgA-3iv3A:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jrk | TAGATOSE1,6-DIPHOSPHATEALDOLASE 2 (Streptococcuspyogenes) |
PF01791(DeoC) | 5 | TYR A 141ILE A 142TYR A 87ILE A 145GLU A 148 | None | 1.35A | 1mrgA-3jrkA:undetectable | 1mrgA-3jrkA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kao | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Staphylococcusaureus) |
PF01791(DeoC) | 5 | TYR A 145ILE A 146TYR A 91ILE A 149GLU A 152 | None | 1.36A | 1mrgA-3kaoA:undetectable | 1mrgA-3kaoA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kes | NUCLEOPORIN NUP145 (Saccharomycescerevisiae) |
PF04096(Nucleoporin2) | 5 | ILE A 494PHE A 520GLY A 492ILE A 548ALA A 546 | NoneNoneEDO A 4 ( 4.8A)NoneNone | 1.30A | 1mrgA-3kesA:undetectable | 1mrgA-3kesA:21.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ku0 | RIBOSOME-INACTIVATING PROTEIN GELONIN (Suregadamultiflora) |
PF00161(RIP) | 7 | TYR A 74PHE A 87GLY A 111TYR A 113ILE A 161GLU A 166ARG A 169 | ADE A 800 (-3.5A)ADE A 800 (-4.6A)ADE A 800 (-4.1A)ADE A 800 (-3.5A)ADE A 800 (-4.0A)ADE A 800 ( 4.5A)ADE A 800 (-2.7A) | 0.32A | 1mrgA-3ku0A:33.9 | 1mrgA-3ku0A:33.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mvg | RIBOSOMEINACTIVATING TYPE 1PROTEIN (Iris xhollandica) |
PF00161(RIP) | 5 | GLY A 106TYR A 108ILE A 156GLU A 161ARG A 164 | GOL A 284 ( 4.9A)GOL A 281 (-4.4A)NoneNoneGOL A 284 (-3.1A) | 0.55A | 1mrgA-3mvgA:32.6 | 1mrgA-3mvgA:33.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myo | TAGATOSE1,6-DIPHOSPHATEALDOLASE 1 (Streptococcuspyogenes) |
PF01791(DeoC) | 5 | TYR A 144ILE A 145TYR A 90ILE A 148GLU A 151 | None | 1.33A | 1mrgA-3myoA:undetectable | 1mrgA-3myoA:24.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nf5 | NUCLEOPORIN NUP116 ([Candida]glabrata) |
PF04096(Nucleoporin2) | 5 | ILE A 927PHE A 950GLY A 925ILE A 977ALA A 975 | None | 1.27A | 1mrgA-3nf5A:undetectable | 1mrgA-3nf5A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o59 | DNA POLYMERASE IILARGE SUBUNIT (Pyrococcushorikoshii) |
PF03833(PolC_DP2) | 5 | TYR X 101ILE X 88GLY X 90ILE X 87ALA X 105 | None | 1.19A | 1mrgA-3o59X:undetectable | 1mrgA-3o59X:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o80 | HEXOKINASE (Kluyveromyceslactis) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 5 | TYR A 269GLY A 237TYR A 239ILE A 402ALA A 401 | None | 1.26A | 1mrgA-3o80A:undetectable | 1mrgA-3o80A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p1u | SUSD HOMOLOG (Parabacteroidesdistasonis) |
PF12741(SusD-like) | 5 | ILE A 230GLY A 393TYR A 390ILE A 395ALA A 233 | None | 1.01A | 1mrgA-3p1uA:undetectable | 1mrgA-3p1uA:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pbp | NUCLEOPORINNUP116/NSP116 (Saccharomycescerevisiae) |
PF04096(Nucleoporin2) | 5 | ILE B1003PHE B1026GLY B1001ILE B1053ALA B1051 | None | 1.31A | 1mrgA-3pbpB:undetectable | 1mrgA-3pbpB:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qy9 | DIHYDRODIPICOLINATEREDUCTASE (Staphylococcusaureus) |
PF01113(DapB_N)PF05173(DapB_C) | 5 | ILE A 3GLY A 28TYR A 40ALA A 19GLU A 20 | None | 1.24A | 1mrgA-3qy9A:undetectable | 1mrgA-3qy9A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tfo | PUTATIVE3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Sinorhizobiummeliloti) |
PF00106(adh_short) | 5 | ILE A 41GLY A 14ILE A 44ALA A 43GLU A 47 | None | 1.03A | 1mrgA-3tfoA:undetectable | 1mrgA-3tfoA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tov | GLYCOSYL TRANSFERASEFAMILY 9 (Veillonellaparvula) |
PF01075(Glyco_transf_9) | 5 | ILE A 185GLY A 211TYR A 209ALA A 338GLU A 339 | None | 1.33A | 1mrgA-3tovA:undetectable | 1mrgA-3tovA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w2z | METHYL-ACCEPTINGCHEMOTAXIS PROTEIN (Nostoc sp. PCC7120) |
PF01590(GAF) | 5 | ILE A 36PHE A 40ILE A 180ALA A 183GLU A 184 | None | 1.34A | 1mrgA-3w2zA:undetectable | 1mrgA-3w2zA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ads | PYRIDOXINEBIOSYNTHETIC ENZYMEPDX1 HOMOLOGUE,PUTATIVE (Plasmodiumberghei) |
PF01680(SOR_SNZ) | 5 | ILE A 25PHE A 213GLY A 234ILE A 43ALA A 42 | None | 1.17A | 1mrgA-4adsA:undetectable | 1mrgA-4adsA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4imv | RICIN (Ricinuscommunis) |
PF00161(RIP) | 5 | PHE A 93GLY A 121TYR A 123ILE A 172GLU A 177 | None | 0.64A | 1mrgA-4imvA:18.5 | 1mrgA-4imvA:26.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ixo | NIFS-LIKE PROTEIN (Rickettsiaafricae) |
PF00266(Aminotran_5) | 5 | ILE A 180GLY A 56TYR A 64ILE A 182ALA A 190 | None | 1.29A | 1mrgA-4ixoA:undetectable | 1mrgA-4ixoA:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mdp | BETA-GLUCOSIDASE (Humicola grisea) |
PF00232(Glyco_hydro_1) | 5 | TYR A 424PHE A 403TYR A 308ALA A 12GLU A 377 | NoneNoneGOL A 507 (-4.1A)NoneGOL A 507 (-3.8A) | 1.28A | 1mrgA-4mdpA:undetectable | 1mrgA-4mdpA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mll | BETA-LACTAMASE OXA-1 (Escherichiacoli) |
PF00905(Transpeptidase) | 5 | ILE A 179PHE A 232GLY A 231ILE A 71ALA A 72 | None | 1.26A | 1mrgA-4mllA:undetectable | 1mrgA-4mllA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rkm | MCCA (Wolinellasuccinogenes) |
no annotation | 5 | ILE A 679GLY A 622TYR A 624ILE A 644ALA A 647 | None | 0.98A | 1mrgA-4rkmA:undetectable | 1mrgA-4rkmA:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4umf | 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATEPHOSPHATASE KDSC (Moraxellacatarrhalis) |
PF00702(Hydrolase) | 5 | ILE A 108GLY A 124TYR A 140ALA A 150GLU A 153 | None | 1.20A | 1mrgA-4umfA:undetectable | 1mrgA-4umfA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxj | GLUTAMATE RECEPTORIIB,GLUTAMATERECEPTOR IIB (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 5 | PHE A 109GLY A 227TYR A 226ALA A 149GLU A 200 | NoneNoneGLU A 301 ( 4.6A)GLU A 301 (-3.0A)GLU A 301 (-2.1A) | 1.34A | 1mrgA-4wxjA:undetectable | 1mrgA-4wxjA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a3y | THERMOLYSIN (Bacillusthermoproteolyticus) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C) | 5 | TYR A 81ILE A 100GLY A 36ILE A 39ALA A 77 | None | 1.13A | 1mrgA-5a3yA:undetectable | 1mrgA-5a3yA:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d55 | HDAB,HDAA (ADHESIN),HUS-ASSOCIATEDDIFFUSE ADHERENCE (Escherichiacoli) |
PF05775(AfaD) | 5 | ILE A 26PHE A 94GLY A 24ILE A 3ALA A 1 | None | 1.30A | 1mrgA-5d55A:undetectable | 1mrgA-5d55A:21.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ddz | RICIN (Ricinuscommunis) |
PF00161(RIP) | 6 | PHE A 93GLY A 121TYR A 123ILE A 172GLU A 177ARG A 180 | None | 0.47A | 1mrgA-5ddzA:33.9 | 1mrgA-5ddzA:32.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ejs | MYOSIN-I HEAVY CHAIN (Dictyosteliumdiscoideum) |
PF00373(FERM_M)PF00784(MyTH4)PF09380(FERM_C) | 5 | ILE A2260GLY A2264TYR A2186ILE A2177GLU A2180 | None | 1.30A | 1mrgA-5ejsA:undetectable | 1mrgA-5ejsA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fxn | THERMOLYSIN (Bacillusthermoproteolyticus) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C) | 5 | TYR A 81ILE A 100GLY A 36ILE A 39ALA A 77 | None | 1.11A | 1mrgA-5fxnA:undetectable | 1mrgA-5fxnA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hjl | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Streptococcusporcinus) |
PF01791(DeoC) | 5 | TYR A 144ILE A 145TYR A 90ILE A 148GLU A 151 | None | 1.35A | 1mrgA-5hjlA:undetectable | 1mrgA-5hjlA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ido | 3' TERMINAL URIDYLYLTRANSFERASE (Trypanosomabrucei) |
PF03828(PAP_assoc) | 5 | ILE A 311GLY A 307ILE A 470ALA A 276GLU A 466 | None | 1.37A | 1mrgA-5idoA:undetectable | 1mrgA-5idoA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijl | DNA POLYMERASE IILARGE SUBUNIT (Pyrococcusabyssi) |
PF03833(PolC_DP2) | 5 | TYR A 98ILE A 85GLY A 87ILE A 84ALA A 102 | None | 1.18A | 1mrgA-5ijlA:undetectable | 1mrgA-5ijlA:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbo | BETA-GLUCOSIDASE (Trichodermaharzianum) |
PF00232(Glyco_hydro_1) | 5 | TYR A 431PHE A 410TYR A 316ALA A 17GLU A 384 | None | 1.18A | 1mrgA-5jboA:undetectable | 1mrgA-5jboA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jhe | PEPTIDYL-PROLYLCIS-TRANS ISOMERASECYP7 (Saccharomycescerevisiae) |
PF00160(Pro_isomerase)PF00515(TPR_1) | 5 | ILE A 243GLY A 214ILE A 242ALA A 239GLU A 238 | None | 1.34A | 1mrgA-5jheA:undetectable | 1mrgA-5jheA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kqw | 4-AMINOBUTYRATETRANSAMINASE (Pseudomonas) |
PF00202(Aminotran_3) | 5 | TYR A 294GLY A 64ILE A 342ALA A 338GLU A 69 | None | 1.26A | 1mrgA-5kqwA:undetectable | 1mrgA-5kqwA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kr6 | 4-AMINOBUTYRATETRANSAMINASE (Pseudomonas) |
PF00202(Aminotran_3) | 5 | TYR A 294GLY A 64ILE A 342ALA A 338GLU A 69 | None | 1.26A | 1mrgA-5kr6A:undetectable | 1mrgA-5kr6A:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mlc | 50S RIBOSOMALPROTEIN L27,CHLOROPLASTIC (Spinaciaoleracea) |
PF01016(Ribosomal_L27) | 5 | ILE X 93PHE X 125GLY X 83ILE X 81ALA X 91 | None G A 867 ( 4.0A) G A 866 ( 3.1A)None A A2371 ( 4.0A) | 1.23A | 1mrgA-5mlcX:undetectable | 1mrgA-5mlcX:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mp7 | RIBOSE-PHOSPHATEPYROPHOSPHOKINASE (Mycolicibacteriumsmegmatis) |
PF13793(Pribosyltran_N)PF14572(Pribosyl_synth) | 5 | GLY A 46ILE A 48ALA A 40GLU A 77ARG A 18 | None | 1.25A | 1mrgA-5mp7A:undetectable | 1mrgA-5mp7A:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tro | PENICILLIN-BINDINGPROTEIN 1 (Staphylococcusaureus) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | ILE A 181GLY A 198ILE A 68ALA A 77ARG A 169 | None | 1.26A | 1mrgA-5troA:undetectable | 1mrgA-5troA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vad | BIFUNCTIONALGLUTAMATE/PROLINE--TRNA LIGASE (Homo sapiens) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF09180(ProRS-C_1) | 5 | TYR A1028GLY A1281TYR A1512ILE A1229ALA A1231 | None | 1.22A | 1mrgA-5vadA:undetectable | 1mrgA-5vadA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xil | PUTATIVE PROLYL-TRNASYNTHETASE (Leishmaniamajor) |
no annotation | 5 | TYR A 267GLY A 519TYR A 756ILE A 467ALA A 469 | ACT A1003 (-4.1A)NoneACT A1003 (-4.5A)NoneNone | 1.23A | 1mrgA-5xilA:undetectable | 1mrgA-5xilA:15.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xtc | NADH DEHYDROGENASE[UBIQUINONE] 1 BETASUBCOMPLEX SUBUNIT10NADH DEHYDROGENASE[UBIQUINONE] 1 BETASUBCOMPLEX SUBUNIT11, MITOCHONDRIAL (Homo sapiens) |
no annotation | 5 | ILE d 96TYR d 10ILE d 99ALA e 122GLU e 123 | None | 1.38A | 1mrgA-5xtcd:undetectable | 1mrgA-5xtcd:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xxf | PROTECTION OFTELOMERES PROTEINPOZ1 (Schizosaccharomycespombe) |
no annotation | 5 | ILE A 54PHE A 235TYR A 219ILE A 106GLU A 107 | None | 1.30A | 1mrgA-5xxfA:undetectable | 1mrgA-5xxfA:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ydg | MULTIPLE ORGANELLARRNA EDITING FACTOR2, CHLOROPLASTIC (Arabidopsisthaliana) |
no annotation | 5 | ILE A 126PHE A 176GLY A 179ILE A 109GLU A 119 | None | 1.32A | 1mrgA-5ydgA:undetectable | 1mrgA-5ydgA:12.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ydg | MULTIPLE ORGANELLARRNA EDITING FACTOR2, CHLOROPLASTIC (Arabidopsisthaliana) |
no annotation | 5 | PHE A 176GLY A 179ILE A 109ALA A 113GLU A 119 | None | 1.26A | 1mrgA-5ydgA:undetectable | 1mrgA-5ydgA:12.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cn1 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Pseudomonasputida) |
no annotation | 5 | ILE A 398GLY A 401ILE A 405GLU A 406ARG A 418 | None | 1.12A | 1mrgA-6cn1A:undetectable | 1mrgA-6cn1A:20.18 |