SIMILAR PATTERNS OF AMINO ACIDS FOR 1MJQ_B_SAMB200
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1akm | ORNITHINETRANSCARBAMYLASE (Escherichiacoli) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | GLY A 180GLU A 174LEU A 197GLU A 200LEU A 204 | None | 1.19A | 1mjqA-1akmA:undetectable1mjqB-1akmA:undetectable | 1mjqA-1akmA:15.021mjqB-1akmA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1brw | PROTEIN (PYRIMIDINENUCLEOSIDEPHOSPHORYLASE) (Geobacillusstearothermophilus) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 5 | GLU A 297ARG A 293LEU A 273GLU A 270HIS A 266 | None | 0.77A | 1mjqA-1brwA:undetectable1mjqB-1brwA:undetectable | 1mjqA-1brwA:15.401mjqB-1brwA:15.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1k | ADRENODOXINREDUCTASE (Bos taurus) |
PF07992(Pyr_redox_2) | 5 | HIS A 460GLU A 433ARG A 437LEU A 448GLU A 453 | None | 1.45A | 1mjqA-1e1kA:undetectable1mjqB-1e1kA:undetectable | 1mjqA-1e1kA:11.831mjqB-1e1kA:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eqw | CU,ZN SUPEROXIDEDISMUTASE (Salmonellaenterica) |
PF00080(Sod_Cu) | 5 | HIS A 118GLY A 138LEU A 97HIS A 44PRO A 72 | CU A 502 (-3.1A)NoneNone CU A 502 (-3.3A)None | 1.27A | 1mjqA-1eqwA:undetectable1mjqB-1eqwA:undetectable | 1mjqA-1eqwA:20.411mjqB-1eqwA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ge7 | PEPTIDYL-LYSMETALLOENDOPEPTIDASE (Grifolafrondosa) |
PF14521(Aspzincin_M35) | 5 | HIS A 59GLY A 126GLU A 118GLU A 157HIS A 156 | NoneNone ZN A 200 ( 4.2A)NoneNone | 1.05A | 1mjqA-1ge7A:undetectable1mjqB-1ge7A:undetectable | 1mjqA-1ge7A:20.001mjqB-1ge7A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h3g | CYCLOMALTODEXTRINASE (Flavobacteriumsp. 92) |
PF00128(Alpha-amylase)PF09087(Cyc-maltodext_N)PF10438(Cyc-maltodext_C) | 5 | GLU A 341GLY A 314LEU A 328LEU A 366PRO A 367 | None | 1.22A | 1mjqA-1h3gA:undetectable1mjqB-1h3gA:undetectable | 1mjqA-1h3gA:10.501mjqB-1h3gA:10.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mjl | METHIONINE REPRESSORPROTEIN METJ (Escherichiacoli) |
PF01340(MetJ) | 7 | GLU A 39ARG A 43LEU A 56GLU A 59HIS A 63LEU A 70PRO A 71 | NoneNoneNoneNoneSAM A 200 ( 2.9A)NoneNone | 0.28A | 1mjqA-1mjlA:14.01mjqB-1mjlA:15.4 | 1mjqA-1mjlA:100.001mjqB-1mjlA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r76 | PECTATE LYASE (Niveispirillumirakense) |
PF09492(Pec_lyase) | 5 | GLY A 77ARG A 135LEU A 70GLU A 73PRO A 137 | None | 1.40A | 1mjqA-1r76A:undetectable1mjqB-1r76A:undetectable | 1mjqA-1r76A:12.251mjqB-1r76A:12.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sdd | COAGULATION FACTOR VCOAGULATION FACTOR V (Bos taurus;Bos taurus) |
PF07732(Cu-oxidase_3)PF00754(F5_F8_type_C)PF07732(Cu-oxidase_3) | 5 | GLU B1846HIS A 85HIS B1804LEU B1842PRO B1858 | CU B2190 ( 4.9A)None CU B2190 (-3.7A)NoneNone | 1.08A | 1mjqA-1sddB:undetectable1mjqB-1sddB:undetectable | 1mjqA-1sddB:10.241mjqB-1sddB:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uio | ADENOSINE DEAMINASE (Mus musculus) |
PF00962(A_deaminase) | 5 | GLU A 260HIS A 214GLY A 237HIS A 17PRO A 297 | None ZN A 400 ( 3.3A)NoneHPR A 353 ( 3.1A)None | 1.47A | 1mjqA-1uioA:undetectable1mjqB-1uioA:undetectable | 1mjqA-1uioA:15.031mjqB-1uioA:15.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xpg | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Thermotogamaritima) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 5 | GLU A 200GLY A 149LEU A 188LEU A 227PRO A 226 | None | 1.14A | 1mjqA-1xpgA:undetectable1mjqB-1xpgA:undetectable | 1mjqA-1xpgA:11.291mjqB-1xpgA:11.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yb3 | HYPOTHETICAL PROTEIN (Pyrococcusfuriosus) |
PF11447(DUF3201) | 5 | GLU A 134PHE A 139GLY A 105LEU A 166GLU A 85 | None | 1.43A | 1mjqA-1yb3A:undetectable1mjqB-1yb3A:undetectable | 1mjqA-1yb3A:20.221mjqB-1yb3A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yem | CONSERVEDHYPOTHETICAL PROTEINPFU-838710-001 (Pyrococcusfuriosus) |
PF01928(CYTH) | 5 | GLU A 2GLU A 161ARG A 157LEU A 162GLU A 155 | None | 1.48A | 1mjqA-1yemA:undetectable1mjqB-1yemA:undetectable | 1mjqA-1yemA:20.571mjqB-1yemA:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z5a | TYPE II DNATOPOISOMERASE VISUBUNIT B (Sulfolobusshibatae) |
PF02518(HATPase_c)PF05833(FbpA)PF09239(Topo-VIb_trans) | 5 | GLY A 318ARG A 193LEU A 371HIS A 414PRO A 378 | None | 1.31A | 1mjqA-1z5aA:undetectable1mjqB-1z5aA:undetectable | 1mjqA-1z5aA:13.501mjqB-1z5aA:13.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2amx | ADENOSINE DEAMINASE (Plasmodiumyoelii) |
PF00962(A_deaminase) | 5 | GLU A 288HIS A 239GLY A 265HIS A 57PRO A 325 | None CO A1000 (-3.4A)None CO A1000 (-3.2A)None | 1.47A | 1mjqA-2amxA:undetectable1mjqB-2amxA:undetectable | 1mjqA-2amxA:15.691mjqB-2amxA:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b24 | NAPHTHALENEDIOXYGENASE SMALLSUBUNIT (Rhodococcus sp.NCIMB 12038) |
PF00866(Ring_hydroxyl_B) | 5 | GLU B 529GLU B 589LEU B 586GLU B 582LEU B 542 | None | 1.40A | 1mjqA-2b24B:undetectable1mjqB-2b24B:undetectable | 1mjqA-2b24B:21.391mjqB-2b24B:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bf4 | NADPH-CYTOCHROMEP450 REDUCTASE (Saccharomycescerevisiae) |
PF00175(NAD_binding_1)PF00258(Flavodoxin_1)PF00667(FAD_binding_1) | 5 | GLU A 120GLY A 121GLU A 184LEU A 182GLU A 168 | None | 1.40A | 1mjqA-2bf4A:undetectable1mjqB-2bf4A:undetectable | 1mjqA-2bf4A:10.631mjqB-2bf4A:10.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ghs | AGR_C_1268P (Agrobacteriumfabrum) |
PF08450(SGL) | 5 | GLU A 238GLY A 239GLU A 40LEU A 38GLU A 281 | NoneNoneEDO A 317 (-3.9A)NoneNone | 1.16A | 1mjqA-2ghsA:undetectable1mjqB-2ghsA:undetectable | 1mjqA-2ghsA:16.131mjqB-2ghsA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ghs | AGR_C_1268P (Agrobacteriumfabrum) |
PF08450(SGL) | 5 | GLY A 237GLU A 281LEU A 37HIS A 294LEU A 283 | None | 1.24A | 1mjqA-2ghsA:undetectable1mjqB-2ghsA:undetectable | 1mjqA-2ghsA:16.131mjqB-2ghsA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gou | OXIDOREDUCTASE,FMN-BINDING (Shewanellaoneidensis) |
PF00724(Oxidored_FMN) | 5 | GLY A 322ARG A 29LEU A 357HIS A 344LEU A 349 | FMN A4401 (-3.4A)NoneNoneNoneFMN A4401 ( 3.8A) | 1.04A | 1mjqA-2gouA:undetectable1mjqB-2gouA:undetectable | 1mjqA-2gouA:14.251mjqB-2gouA:14.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ie8 | PHOSPHOGLYCERATEKINASE (Thermuscaldophilus) |
PF00162(PGK) | 5 | GLU A 75GLY A 74GLU A 99LEU A 103GLU A 107 | None | 1.37A | 1mjqA-2ie8A:undetectable1mjqB-2ie8A:undetectable | 1mjqA-2ie8A:15.121mjqB-2ie8A:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2krk | 26S PROTEASEREGULATORY SUBUNIT 8 (Homo sapiens) |
no annotation | 5 | HIS A 10GLY A 44ARG A 36LEU A 17GLU A 14 | None | 1.45A | 1mjqA-2krkA:undetectable1mjqB-2krkA:undetectable | 1mjqA-2krkA:20.911mjqB-2krkA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2liw | CURA (Lyngbyamajuscula) |
PF00550(PP-binding) | 5 | GLU A1994PHE A1982GLY A1992GLU A1975LEU A1969 | None | 1.46A | 1mjqA-2liwA:undetectable1mjqB-2liwA:undetectable | 1mjqA-2liwA:25.221mjqB-2liwA:25.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2peb | PUTATIVE DIOXYGENASE (Nostocpunctiforme) |
PF08883(DOPA_dioxygen) | 5 | HIS A 51GLY A 49GLU A 110HIS A 94LEU A 112 | UNL A 201 (-4.0A)NoneNoneUNL A 201 (-3.9A)None | 1.38A | 1mjqA-2pebA:undetectable1mjqB-2pebA:undetectable | 1mjqA-2pebA:17.191mjqB-2pebA:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3n | CARBONIC ANHYDRASE 2 (Cryptococcusneoformans) |
PF00484(Pro_CA) | 5 | GLU A 141GLU A 154HIS A 161LEU A 138PRO A 139 | None | 1.45A | 1mjqA-2w3nA:undetectable1mjqB-2w3nA:undetectable | 1mjqA-2w3nA:20.351mjqB-2w3nA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x0q | ALCALIGINBIOSYNTHESIS PROTEIN (Bordetellabronchiseptica) |
PF04183(IucA_IucC)PF06276(FhuF) | 5 | HIS A 514PHE A 512GLY A 510LEU A 519HIS A 79 | None | 1.44A | 1mjqA-2x0qA:undetectable1mjqB-2x0qA:undetectable | 1mjqA-2x0qA:11.841mjqB-2x0qA:11.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x60 | MANNOSE-1-PHOSPHATEGUANYLYLTRANSFERASE (Thermotogamaritima) |
PF00483(NTP_transferase) | 5 | GLU A 47ARG A 38LEU A 69GLU A 71LEU A 45 | None | 1.31A | 1mjqA-2x60A:undetectable1mjqB-2x60A:undetectable | 1mjqA-2x60A:15.921mjqB-2x60A:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3a | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE3-KINASE CATALYTICSUBUNIT BETA ISOFORM (Mus musculus) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka)PF00792(PI3K_C2)PF00794(PI3K_rbd)PF02192(PI3K_p85B) | 5 | GLY A 619GLU A 599GLU A 602LEU A 603PRO A 568 | None | 1.31A | 1mjqA-2y3aA:undetectable1mjqB-2y3aA:undetectable | 1mjqA-2y3aA:7.521mjqB-2y3aA:7.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yp2 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 5 | PHE A 87GLY A 116GLU A 89ARG A 269GLU A 396 | None | 1.18A | 1mjqA-2yp2A:undetectable1mjqB-2yp2A:undetectable | 1mjqA-2yp2A:11.021mjqB-2yp2A:11.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aeu | LIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT N (Rhodobactercapsulatus) |
PF00148(Oxidored_nitro) | 5 | HIS A 330PHE A 225GLU A 154LEU A 158LEU A 221 | None | 1.32A | 1mjqA-3aeuA:undetectable1mjqB-3aeuA:undetectable | 1mjqA-3aeuA:14.111mjqB-3aeuA:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aw8 | PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXYLASE, ATPASESUBUNIT (Thermusthermophilus) |
PF02222(ATP-grasp) | 5 | GLU A 172GLY A 173GLU A 253LEU A 255PRO A 110 | AMP A 370 (-4.4A)NoneNoneNoneNone | 1.36A | 1mjqA-3aw8A:undetectable1mjqB-3aw8A:undetectable | 1mjqA-3aw8A:14.161mjqB-3aw8A:14.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bru | REGULATORY PROTEIN,TETR FAMILY (Rhodobactersphaeroides) |
PF00440(TetR_N)PF16925(TetR_C_13) | 5 | HIS A 212GLY A 210LEU A 159HIS A 173LEU A 169 | None | 1.41A | 1mjqA-3bruA:1.21mjqB-3bruA:undetectable | 1mjqA-3bruA:25.421mjqB-3bruA:25.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bxw | CHITINASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
no annotation | 5 | GLY B 363ARG B 26LEU B 28GLU B 41HIS B 42 | None | 1.41A | 1mjqA-3bxwB:undetectable1mjqB-3bxwB:undetectable | 1mjqA-3bxwB:14.511mjqB-3bxwB:14.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3byr | CZRB PROTEIN (Thermusthermophilus) |
PF16916(ZT_dimer) | 5 | GLU A 67PHE A 43ARG A 37GLU A 11LEU A 77 | None | 1.18A | 1mjqA-3byrA:undetectable1mjqB-3byrA:undetectable | 1mjqA-3byrA:28.071mjqB-3byrA:28.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cvw | RE11660P (Drosophilamelanogaster) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7) | 5 | GLU A 108GLY A 15LEU A 78HIS A 10LEU A 24 | None | 1.26A | 1mjqA-3cvwA:undetectable1mjqB-3cvwA:undetectable | 1mjqA-3cvwA:11.991mjqB-3cvwA:11.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dcp | HISTIDINOL-PHOSPHATASE (Listeriamonocytogenes) |
PF02811(PHP)PF13263(PHP_C) | 5 | HIS A 123PHE A 136GLU A 56HIS A 40PRO A 13 | FE A 310 (-3.3A)NoneNone ZN A 301 (-3.5A)None | 0.89A | 1mjqA-3dcpA:undetectable1mjqB-3dcpA:undetectable | 1mjqA-3dcpA:16.861mjqB-3dcpA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dmy | PROTEIN FDRA (Escherichiacoli) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 5 | GLY A 182LEU A 169HIS A 222LEU A 508PRO A 505 | None | 1.46A | 1mjqA-3dmyA:undetectable1mjqB-3dmyA:undetectable | 1mjqA-3dmyA:13.021mjqB-3dmyA:13.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | GLU A1019PHE A 486GLY A 488GLU A 508ARG A 512 | None | 1.40A | 1mjqA-3dy5A:undetectable1mjqB-3dy5A:undetectable | 1mjqA-3dy5A:7.131mjqB-3dy5A:7.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewd | ADENOSINE DEAMINASE (Plasmodiumvivax) |
PF00962(A_deaminase) | 5 | GLU A 274HIS A 225GLY A 251HIS A 44PRO A 311 | None ZN A 371 ( 3.4A)NoneMCF A 372 ( 3.3A)None | 1.47A | 1mjqA-3ewdA:undetectable1mjqB-3ewdA:undetectable | 1mjqA-3ewdA:14.401mjqB-3ewdA:14.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fjo | NADPH-CYTOCHROMEP450 REDUCTASE (Saccharomycescerevisiae;Homo sapiens) |
PF00175(NAD_binding_1)PF00258(Flavodoxin_1)PF00667(FAD_binding_1) | 5 | GLU A 120GLY A 121GLU A 184LEU A 182GLU A 168 | None | 1.35A | 1mjqA-3fjoA:undetectable1mjqB-3fjoA:undetectable | 1mjqA-3fjoA:11.251mjqB-3fjoA:11.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gkb | PUTATIVE ENOYL-COAHYDRATASE (Streptomycesavermitilis) |
PF00378(ECH_1) | 5 | GLU A 234GLY A 150ARG A 39LEU A 82PRO A 87 | None | 1.47A | 1mjqA-3gkbA:undetectable1mjqB-3gkbA:undetectable | 1mjqA-3gkbA:16.371mjqB-3gkbA:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 5 | GLU A 533GLY A 534LEU A 436LEU A 541PRO A 542 | None | 1.42A | 1mjqA-3i04A:undetectable1mjqB-3i04A:undetectable | 1mjqA-3i04A:10.241mjqB-3i04A:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9e | VP5 (Bluetonguevirus) |
PF00901(Orbi_VP5) | 5 | GLU D 427ARG D 423GLU D 405HIS D 380LEU D 407 | None | 1.43A | 1mjqA-3j9eD:0.91mjqB-3j9eD:undetectable | 1mjqA-3j9eD:13.661mjqB-3j9eD:13.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l84 | TRANSKETOLASE (Campylobacterjejuni) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | GLU A 291PHE A 75GLY A 80LEU A 71HIS A 77 | GOL A2002 (-2.6A)NoneGOL A2002 ( 4.1A)NoneGOL A2002 (-4.4A) | 1.32A | 1mjqA-3l84A:undetectable1mjqB-3l84A:undetectable | 1mjqA-3l84A:10.191mjqB-3l84A:10.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lj0 | SERINE/THREONINE-PROTEINKINASE/ENDORIBONUCLEASE IRE1 (Saccharomycescerevisiae) |
PF00069(Pkinase)PF06479(Ribonuc_2-5A) | 5 | HIS A 725GLY A 784LEU A 718GLU A 721LEU A 791 | None | 1.28A | 1mjqA-3lj0A:undetectable1mjqB-3lj0A:undetectable | 1mjqA-3lj0A:13.231mjqB-3lj0A:13.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3loq | UNIVERSAL STRESSPROTEIN (Archaeoglobusfulgidus) |
PF00582(Usp) | 5 | GLU A 27PHE A -4GLY A 25ARG A 161LEU A -6 | None | 1.40A | 1mjqA-3loqA:undetectable1mjqB-3loqA:undetectable | 1mjqA-3loqA:20.551mjqB-3loqA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0u | PROBABLEN-GLYCOSYLASE/DNALYASE (Thermotogamaritima) |
no annotation | 5 | GLY A 64GLU A 74HIS A 69LEU A 70PRO A 71 | None | 1.43A | 1mjqA-3n0uA:undetectable1mjqB-3n0uA:undetectable | 1mjqA-3n0uA:21.331mjqB-3n0uA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pbk | FATTY ACYL-ADENYLATELIGASE (Escherichiacoli) |
PF00501(AMP-binding) | 5 | GLY A 489ARG A 514LEU A 518GLU A 483PRO A 484 | None | 1.47A | 1mjqA-3pbkA:undetectable1mjqB-3pbkA:undetectable | 1mjqA-3pbkA:13.591mjqB-3pbkA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pie | 5'->3'EXORIBONUCLEASE(XRN1) (Kluyveromyceslactis) |
PF03159(XRN_N) | 5 | GLU A 370ARG A 13LEU A 750LEU A 364PRO A 307 | None | 1.40A | 1mjqA-3pieA:1.41mjqB-3pieA:1.0 | 1mjqA-3pieA:7.441mjqB-3pieA:7.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qde | CELLOBIOSEPHOSPHORYLASE (Ruminiclostridiumthermocellum) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 5 | PHE A 627GLY A 643ARG A 564LEU A 485LEU A 622 | None | 1.48A | 1mjqA-3qdeA:0.01mjqB-3qdeA:undetectable | 1mjqA-3qdeA:9.461mjqB-3qdeA:9.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rac | HISTIDINE-TRNALIGASE (Alicyclobacillusacidocaldarius) |
PF13393(tRNA-synt_His) | 5 | GLU A 354GLU A 307LEU A 308GLU A 95PRO A 94 | GOL A 371 ( 4.8A)NoneNoneLMR A 401 (-3.4A)None | 1.39A | 1mjqA-3racA:undetectable1mjqB-3racA:undetectable | 1mjqA-3racA:13.481mjqB-3racA:13.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s51 | FANCONI ANEMIA GROUPI PROTEIN HOMOLOG (Mus musculus) |
PF14674(FANCI_S1-cap)PF14675(FANCI_S1)PF14676(FANCI_S2)PF14677(FANCI_S3)PF14678(FANCI_S4)PF14679(FANCI_HD1)PF14680(FANCI_HD2) | 5 | GLU A 909PHE A 915GLY A 910ARG A 990LEU A 919 | None | 1.28A | 1mjqA-3s51A:undetectable1mjqB-3s51A:undetectable | 1mjqA-3s51A:6.571mjqB-3s51A:6.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sdo | NITRILOTRIACETATEMONOOXYGENASE (Burkholderiapseudomallei) |
PF00296(Bac_luciferase) | 5 | GLU A 279GLY A 274ARG A 41LEU A 401HIS A 407 | None | 1.35A | 1mjqA-3sdoA:0.71mjqB-3sdoA:undetectable | 1mjqA-3sdoA:15.661mjqB-3sdoA:15.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3twk | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 1 (Arabidopsisthaliana) |
PF01149(Fapy_DNA_glyco)PF06831(H2TH) | 5 | HIS A 36PHE A 43GLY A 37LEU A 134PRO A 137 | None | 1.39A | 1mjqA-3twkA:undetectable1mjqB-3twkA:undetectable | 1mjqA-3twkA:18.731mjqB-3twkA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3txx | PUTRESCINECARBAMOYLTRANSFERASE (Enterococcusfaecalis) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | GLU A 71PHE A 59GLY A 70LEU A 304PRO A 120 | None | 1.22A | 1mjqA-3txxA:0.51mjqB-3txxA:0.6 | 1mjqA-3txxA:14.481mjqB-3txxA:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3unv | ADMH (Pantoeaagglomerans) |
PF00221(Lyase_aromatic) | 5 | GLU A 276GLY A 273ARG A 395LEU A 391LEU A 244 | None | 1.20A | 1mjqA-3unvA:undetectable1mjqB-3unvA:undetectable | 1mjqA-3unvA:12.391mjqB-3unvA:12.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vex | O-CARBAMOYLTRANSFERASE TOBZ (Streptoalloteichustenebrarius) |
PF02543(Carbam_trans_N)PF16861(Carbam_trans_C) | 5 | GLY A 407GLU A 393GLU A 395LEU A 563PRO A 389 | None | 1.42A | 1mjqA-3vexA:undetectable1mjqB-3vexA:undetectable | 1mjqA-3vexA:11.991mjqB-3vexA:11.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vi1 | ALKALINEMETALLOPROTEINASE (Pseudomonasaeruginosa) |
PF08548(Peptidase_M10_C)PF13583(Reprolysin_4) | 5 | HIS A 186LEU A 40HIS A 180LEU A 139PRO A 140 | ZN A 500 (-3.2A)None ZN A 500 (-3.3A)NoneNone | 1.46A | 1mjqA-3vi1A:undetectable1mjqB-3vi1A:undetectable | 1mjqA-3vi1A:11.551mjqB-3vi1A:11.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w53 | BETA-GLUCOSIDASE (Micrococcusantarcticus) |
PF00232(Glyco_hydro_1) | 5 | GLY A 206GLU A 214LEU A 215GLU A 152LEU A 148 | None | 1.39A | 1mjqA-3w53A:undetectable1mjqB-3w53A:undetectable | 1mjqA-3w53A:12.691mjqB-3w53A:12.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9v | PHOSPHATE-BINDINGPROTEIN (unidentifiedprokaryoticorganism) |
PF12849(PBP_like_2) | 5 | GLU A 142GLY A 31GLU A 68LEU A 40GLU A 41 | NonePO4 A 401 (-3.5A)NoneNoneNone | 1.33A | 1mjqA-3w9vA:undetectable1mjqB-3w9vA:undetectable | 1mjqA-3w9vA:13.001mjqB-3w9vA:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3whe | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 5 | PHE A 87GLY A 116GLU A 89ARG A 269GLU A 396 | None | 1.17A | 1mjqA-3wheA:undetectable1mjqB-3wheA:undetectable | 1mjqA-3wheA:12.031mjqB-3wheA:12.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wqy | ALANINE--TRNA LIGASE (Archaeoglobusfulgidus) |
PF01411(tRNA-synt_2c)PF02272(DHHA1)PF07973(tRNA_SAD) | 5 | GLY A 615ARG A 418LEU A 414GLU A 415PRO A 357 | None | 1.37A | 1mjqA-3wqyA:undetectable1mjqB-3wqyA:undetectable | 1mjqA-3wqyA:8.011mjqB-3wqyA:8.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zwf | ZINCPHOSPHODIESTERASEELAC PROTEIN 1 (Homo sapiens) |
PF00753(Lactamase_B)PF12706(Lactamase_B_2) | 5 | GLU A 275HIS A 67LEU A 123HIS A 62PRO A 185 | None ZN A1363 (-3.4A)None ZN A1364 (-3.5A)None | 1.45A | 1mjqA-3zwfA:undetectable1mjqB-3zwfA:undetectable | 1mjqA-3zwfA:13.201mjqB-3zwfA:13.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c9m | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 5 | GLU A 37PHE A 40GLY A 35ARG A 299LEU A 335 | None | 1.48A | 1mjqA-4c9mA:undetectable1mjqB-4c9mA:undetectable | 1mjqA-4c9mA:12.771mjqB-4c9mA:12.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4glf | RSFP (unculturedbacterium) |
PF01048(PNP_UDP_1) | 5 | GLY A 23ARG A 34LEU A 51GLU A 53LEU A 30 | None | 1.28A | 1mjqA-4glfA:undetectable1mjqB-4glfA:undetectable | 1mjqA-4glfA:16.491mjqB-4glfA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hh8 | BUTYROPHILINSUBFAMILY 1 MEMBERA1 (Bos taurus) |
PF07686(V-set)PF08205(C2-set_2) | 5 | PHE A 99GLU A 36ARG A 52LEU A 50GLU A 60 | None | 1.12A | 1mjqA-4hh8A:undetectable1mjqB-4hh8A:undetectable | 1mjqA-4hh8A:18.261mjqB-4hh8A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hvt | POST-PROLINECLEAVING ENZYME (Rickettsiatyphi) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 5 | GLY A 151GLU A 31LEU A 36GLU A 676PRO A 654 | None | 1.40A | 1mjqA-4hvtA:undetectable1mjqB-4hvtA:undetectable | 1mjqA-4hvtA:8.931mjqB-4hvtA:8.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4joi | CST COMPLEX SUBUNITTEN1 (Homo sapiens) |
no annotation | 5 | GLU D 78GLY D 77ARG D 113LEU D 11GLU D 14 | None | 1.45A | 1mjqA-4joiD:undetectable1mjqB-4joiD:undetectable | 1mjqA-4joiD:22.501mjqB-4joiD:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ojz | PUTATIVE ALGINATELYASE (Saccharophagusdegradans) |
PF05426(Alginate_lyase)PF07940(Hepar_II_III) | 5 | HIS A 415GLY A 414GLU A 505LEU A 419HIS A 464 | ZN A 801 (-3.2A)NoneNoneNone ZN A 801 (-3.3A) | 1.45A | 1mjqA-4ojzA:undetectable1mjqB-4ojzA:undetectable | 1mjqA-4ojzA:9.361mjqB-4ojzA:9.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oo2 | CHLOROPHENOL-4-MONOOXYGENASE (Streptomycesglobisporus) |
PF03241(HpaB)PF11794(HpaB_N) | 5 | GLU A 266HIS A 458LEU A 323LEU A 260PRO A 259 | None | 1.46A | 1mjqA-4oo2A:undetectable1mjqB-4oo2A:undetectable | 1mjqA-4oo2A:12.241mjqB-4oo2A:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r81 | NADH DEHYDROGENASE (Methanothermobactermarburgensis) |
PF02525(Flavodoxin_2) | 5 | GLY A 108ARG A 103GLU A 52LEU A 65PRO A 66 | None | 1.30A | 1mjqA-4r81A:undetectable1mjqB-4r81A:undetectable | 1mjqA-4r81A:18.181mjqB-4r81A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u8h | CRYPTOCHROME-2 (Mus musculus) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7) | 5 | GLU A 401GLY A 66GLU A 215LEU A 216PRO A 57 | None | 1.42A | 1mjqA-4u8hA:undetectable1mjqB-4u8hA:undetectable | 1mjqA-4u8hA:12.081mjqB-4u8hA:12.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x2d | FIC FAMILY PROTEINPUTATIVEFILAMENTATIONINDUCED BY CAMPPROTEIN (Clostridioidesdifficile) |
PF02661(Fic) | 5 | PHE A 165ARG A 171LEU A 95GLU A 64LEU A 101 | NoneATP A 302 (-4.0A)NoneNoneNone | 1.43A | 1mjqA-4x2dA:undetectable1mjqB-4x2dA:undetectable | 1mjqA-4x2dA:15.511mjqB-4x2dA:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x4j | PUTATIVE OXYGENASE (Amycolatopsisorientalis) |
PF01494(FAD_binding_3) | 5 | GLY A 108GLU A 32GLU A 100LEU A 15PRO A 12 | NoneFAD A 503 (-2.5A)FAD A 503 ( 4.9A)NoneFAD A 503 (-3.9A) | 1.31A | 1mjqA-4x4jA:undetectable1mjqB-4x4jA:undetectable | 1mjqA-4x4jA:10.541mjqB-4x4jA:10.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xac | EVDO2 (Micromonosporacarbonacea) |
PF05721(PhyH) | 5 | GLU A 79GLY A 113ARG A 93GLU A 34PRO A 89 | None | 1.28A | 1mjqA-4xacA:undetectable1mjqB-4xacA:undetectable | 1mjqA-4xacA:18.071mjqB-4xacA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xyd | NITRIC-OXIDEREDUCTASE SUBUNIT BNORC-LIKE PROTEIN (Roseobacterdenitrificans;Roseobacterdenitrificans) |
PF00115(COX1)PF00034(Cytochrom_C) | 5 | GLU A 119GLY A 120LEU B 121GLU B 125HIS B 55 | None | 1.21A | 1mjqA-4xydA:undetectable1mjqB-4xydA:undetectable | 1mjqA-4xydA:12.721mjqB-4xydA:12.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zu9 | ELONGATION FACTORSELB (Aquifexaeolicus) |
PF00009(GTP_EFTU)PF09107(SelB-wing_3) | 5 | HIS A 14GLY A 91GLU A 140LEU A 100HIS A 11 | None | 1.46A | 1mjqA-4zu9A:undetectable1mjqB-4zu9A:undetectable | 1mjqA-4zu9A:10.241mjqB-4zu9A:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5anb | ELONGATION FACTOR TUGTP-BINDINGDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF14492(EFG_II) | 5 | GLU K 904GLY K 924LEU K 865LEU K 748PRO K 745 | None | 1.46A | 1mjqA-5anbK:undetectable1mjqB-5anbK:undetectable | 1mjqA-5anbK:8.471mjqB-5anbK:8.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5anb | ELONGATION FACTOR TUGTP-BINDINGDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF14492(EFG_II) | 5 | GLU K 926GLY K 924LEU K 865LEU K 748PRO K 745 | None | 1.29A | 1mjqA-5anbK:undetectable1mjqB-5anbK:undetectable | 1mjqA-5anbK:8.471mjqB-5anbK:8.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cfi | BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE(DIADENOSINETETRAPHOSPHATASE),PUTATIVE (Plasmodiumfalciparum) |
PF00293(NUDIX) | 5 | GLU A 126GLY A 123LEU A 85LEU A 132PRO A 133 | None | 1.26A | 1mjqA-5cfiA:undetectable1mjqB-5cfiA:undetectable | 1mjqA-5cfiA:18.541mjqB-5cfiA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5doi | TELOMERASE-ASSOCIATED PROTEIN 19TELOMERASEASSOCIATED PROTEINP45 (Tetrahymenathermophila;Tetrahymenathermophila) |
no annotationno annotation | 5 | PHE E 76ARG A 38LEU E 27GLU E 112HIS E 107 | None | 1.39A | 1mjqA-5doiE:undetectable1mjqB-5doiE:undetectable | 1mjqA-5doiE:17.561mjqB-5doiE:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e5u | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE GAMMA (Mus musculus) |
PF00194(Carb_anhydrase) | 5 | GLU A 149PHE A 178ARG A 251LEU A 139GLU A 266 | None | 1.47A | 1mjqA-5e5uA:undetectable1mjqB-5e5uA:undetectable | 1mjqA-5e5uA:19.111mjqB-5e5uA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ej1 | PUTATIVE CELLULOSESYNTHASE (Rhodobactersphaeroides) |
PF00535(Glycos_transf_2)PF03552(Cellulose_synt)PF07238(PilZ) | 5 | HIS A 224PHE A 335GLY A 337ARG A 326LEU A 234 | None | 1.25A | 1mjqA-5ej1A:undetectable1mjqB-5ej1A:undetectable | 1mjqA-5ej1A:9.131mjqB-5ej1A:9.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5esr | HALOALKANEDEHALOGENASE (Caulobactervibrioides) |
PF00561(Abhydrolase_1) | 5 | GLU A 206GLY A 207LEU A 179LEU A 173PRO A 174 | None | 1.34A | 1mjqA-5esrA:undetectable1mjqB-5esrA:undetectable | 1mjqA-5esrA:18.031mjqB-5esrA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fcd | MCCD (Escherichiacoli) |
PF13649(Methyltransf_25) | 5 | PHE A 119GLY A 149LEU A 112GLU A 140HIS A 142 | None | 1.38A | 1mjqA-5fcdA:undetectable1mjqB-5fcdA:undetectable | 1mjqA-5fcdA:17.621mjqB-5fcdA:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fnp | IRON-SULFUR CLUSTERREPAIR PROTEIN YTFE (Escherichiacoli) |
PF01814(Hemerythrin)PF04405(ScdA_N) | 5 | HIS A 160GLU A 165LEU A 166GLU A 125HIS A 129 | ZN A1221 (-3.3A)NoneNoneNone ZN A1221 ( 3.2A) | 1.41A | 1mjqA-5fnpA:undetectable1mjqB-5fnpA:undetectable | 1mjqA-5fnpA:16.431mjqB-5fnpA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fqd | DNA DAMAGE-BINDINGPROTEIN 1 (Homo sapiens) |
PF03178(CPSF_A)PF10433(MMS1_N) | 5 | HIS A 22PHE A 23ARG A 103LEU A 76GLU A 72 | None | 1.23A | 1mjqA-5fqdA:undetectable1mjqB-5fqdA:undetectable | 1mjqA-5fqdA:8.621mjqB-5fqdA:8.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5g | PUTATIVE XANTHINEDEHYDROGENASE YAGSFAD-BINDING SUBUNIT (Escherichiacoli) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 5 | HIS C 109GLY C 55GLU C 106LEU C 311GLU C 345 | None | 1.43A | 1mjqA-5g5gC:undetectable1mjqB-5g5gC:undetectable | 1mjqA-5g5gC:9.151mjqB-5g5gC:9.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5j | FERREDOXIN--NADPREDUCTASE (Zea mays) |
PF00175(NAD_binding_1) | 5 | GLY A 63ARG A 187GLU A 19HIS A 17LEU A 18 | None | 1.43A | 1mjqA-5h5jA:undetectable1mjqB-5h5jA:undetectable | 1mjqA-5h5jA:16.991mjqB-5h5jA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hcc | COMPLEMENT C5 (Homo sapiens) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF07677(A2M_recep)PF07678(A2M_comp) | 5 | GLY A1283GLU A1009HIS A1002LEU A1003PRO A1004 | None | 1.44A | 1mjqA-5hccA:undetectable1mjqB-5hccA:undetectable | 1mjqA-5hccA:7.621mjqB-5hccA:7.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2g | DIOL DEHYDRATASE (Roseburiainulinivorans) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | GLU A 440GLY A 437GLU A 527LEU A 276HIS A 283 | PGO A 901 (-2.8A)PGO A 901 (-3.3A)NoneNonePGO A 901 (-4.0A) | 1.46A | 1mjqA-5i2gA:0.11mjqB-5i2gA:undetectable | 1mjqA-5i2gA:10.491mjqB-5i2gA:10.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikp | GLYCOGENPHOSPHORYLASE, BRAINFORM (Homo sapiens) |
PF00343(Phosphorylase) | 5 | GLU A 730PHE A 774GLU A 737LEU A 735PRO A 736 | None | 1.35A | 1mjqA-5ikpA:undetectable1mjqB-5ikpA:undetectable | 1mjqA-5ikpA:9.051mjqB-5ikpA:9.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iq0 | ESTERASE (unculturedbacterium) |
PF07859(Abhydrolase_3) | 5 | GLY A 21GLU A 301ARG A 306GLU A 249PRO A 10 | None | 1.47A | 1mjqA-5iq0A:undetectable1mjqB-5iq0A:undetectable | 1mjqA-5iq0A:19.171mjqB-5iq0A:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iud | DNA POLYMERASE ALPHACATALYTIC SUBUNIT (Homo sapiens) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | GLY A 782GLU A 789ARG A 966LEU A 793GLU A 485 | None | 1.47A | 1mjqA-5iudA:undetectable1mjqB-5iudA:undetectable | 1mjqA-5iudA:8.501mjqB-5iudA:8.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oie | - (-) |
no annotation | 5 | GLY A 220LEU A 229GLU A 230LEU A 199PRO A 200 | None | 0.90A | 1mjqA-5oieA:undetectable1mjqB-5oieA:undetectable | 1mjqA-5oieA:undetectable1mjqB-5oieA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5op0 | DNA POLYMERASE LIGD,POLYMERASE DOMAIN (Mycolicibacteriumsmegmatis) |
no annotation | 5 | GLY B 299GLU B 206ARG B 210LEU B 163GLU B 166 | None | 1.15A | 1mjqA-5op0B:undetectable1mjqB-5op0B:undetectable | 1mjqA-5op0B:17.301mjqB-5op0B:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w25 | ASPARTATE--TRNA(ASP/ASN) LIGASE (Mycobacteriumtuberculosis) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon)PF02938(GAD) | 5 | GLY A 507GLU A 500ARG A 496LEU A 521GLU A 514 | None | 1.45A | 1mjqA-5w25A:undetectable1mjqB-5w25A:undetectable | 1mjqA-5w25A:10.521mjqB-5w25A:10.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xfa | NAD-REDUCINGHYDROGENASENAD-REDUCINGHYDROGENASE (Hydrogenophilusthermoluteolus;Hydrogenophilusthermoluteolus) |
PF01257(2Fe-2S_thioredx)PF01512(Complex1_51K)PF10589(NADH_4Fe-4S)PF10588(NADH-G_4Fe-4S_3)PF13459(Fer4_15)PF13510(Fer2_4) | 5 | GLY A 328LEU B 164GLU B 169LEU A 41PRO A 42 | None | 1.14A | 1mjqA-5xfaA:undetectable1mjqB-5xfaA:undetectable | 1mjqA-5xfaA:9.861mjqB-5xfaA:9.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xrw | FLINFLIY (Helicobacterpylori;Helicobacterpylori) |
no annotationno annotation | 5 | GLU A 51PHE C 268GLY A 53GLU C 260LEU C 247 | None | 1.39A | 1mjqA-5xrwA:undetectable1mjqB-5xrwA:undetectable | 1mjqA-5xrwA:undetectable1mjqB-5xrwA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c9m | N-ALPHA-ACETYLTRANSFERASE 15, NATAAUXILIARY SUBUNIT (Homo sapiens) |
no annotation | 5 | LEU A 13GLU A 10HIS A 45LEU A 6PRO A 7 | None | 1.43A | 1mjqA-6c9mA:undetectable1mjqB-6c9mA:undetectable | 1mjqA-6c9mA:undetectable1mjqB-6c9mA:undetectable |