SIMILAR PATTERNS OF AMINO ACIDS FOR 1MJ2_C_SAMC1200_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1de6 L-RHAMNOSE ISOMERASE

(Escherichia
coli)
PF06134
(RhaA)
4 HIS A 228
ALA A 178
PHE A 180
GLY A 181
None
1.32A 1mj2D-1de6A:
undetectable
1mj2D-1de6A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eg7 FORMYLTETRAHYDROFOLA
TE SYNTHETASE


(Moorella
thermoacetica)
PF01268
(FTHFS)
4 HIS A1280
ALA A1279
PHE A1275
GLY A1281
None
1.37A 1mj2D-1eg7A:
undetectable
1mj2D-1eg7A:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gz7 LIPASE 2

(Diutina rugosa)
PF00135
(COesterase)
4 HIS A 180
ALA A 177
PHE A  38
GLY A 175
GOL  A1538 (-3.9A)
None
None
None
1.30A 1mj2D-1gz7A:
undetectable
1mj2D-1gz7A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hw2 FATTY ACID
METABOLISM REGULATOR
PROTEIN


(Escherichia
coli)
PF00392
(GntR)
PF07840
(FadR_C)
4 HIS A 120
ALA A 155
PHE A 154
GLY A 157
None
1.14A 1mj2D-1hw2A:
undetectable
1mj2D-1hw2A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ii2 PHOSPHOENOLPYRUVATE
CARBOXYKINASE


(Trypanosoma
cruzi)
PF01293
(PEPCK_ATP)
4 HIS A 205
ALA A 206
PHE A 219
GLY A 221
None
1.39A 1mj2D-1ii2A:
undetectable
1mj2D-1ii2A:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3n 3-OXOACYL-(ACYL-CARR
IER PROTEIN)
SYNTHASE II


(Thermus
thermophilus)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
4 HIS A 399
ALA A 395
PHE A 396
GLY A 397
None
1.40A 1mj2D-1j3nA:
undetectable
1mj2D-1j3nA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1khd ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE


(Pectobacterium
carotovorum)
PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
4 HIS A  32
ALA A  71
PHE A  35
GLY A  67
None
1.35A 1mj2D-1khdA:
undetectable
1mj2D-1khdA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lns X-PROLYL DIPEPTIDYL
AMINOPEPTIDASE


(Lactococcus
lactis)
PF02129
(Peptidase_S15)
PF08530
(PepX_C)
PF09168
(PepX_N)
4 HIS A 464
ALA A 476
PHE A 479
GLY A 373
None
1.31A 1mj2D-1lnsA:
undetectable
1mj2D-1lnsA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lwd ISOCITRATE
DEHYDROGENASE


(Sus scrofa)
PF00180
(Iso_dh)
4 HIS A 194
ALA A 193
PHE A 192
GLY A 191
None
1.24A 1mj2D-1lwdA:
undetectable
1mj2D-1lwdA:
14.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mjl METHIONINE REPRESSOR
PROTEIN METJ


(Escherichia
coli)
PF01340
(MetJ)
4 HIS A  63
ALA A  64
PHE A  65
GLY A  67
SAM  A 200 ( 2.9A)
SAM  A 200 (-4.0A)
SAM  A 200 (-3.8A)
SAM  A 200 ( 4.1A)
0.25A 1mj2D-1mjlA:
15.5
1mj2D-1mjlA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s2n EXTRACELLULAR
SUBTILISIN-LIKE
SERINE PROTEINASE


(Vibrio sp.
PA-44)
PF00082
(Peptidase_S8)
4 HIS A 225
ALA A 199
PHE A 198
GLY A 201
None
1.22A 1mj2D-1s2nA:
undetectable
1mj2D-1s2nA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1suw PROBABLE INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE


(Archaeoglobus
fulgidus)
PF01513
(NAD_kinase)
4 HIS A  78
ALA A  79
PHE A  84
GLY A  67
None
1.39A 1mj2D-1suwA:
undetectable
1mj2D-1suwA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szn ALPHA-GALACTOSIDASE

(Trichoderma
reesei)
PF16499
(Melibiase_2)
4 HIS A 196
ALA A 122
PHE A 121
GLY A 125
None
1.23A 1mj2D-1sznA:
undetectable
1mj2D-1sznA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqz LIPOATE-PROTEIN
LIGASE, PUTATIVE


(Streptococcus
pneumoniae)
PF03099
(BPL_LplA_LipB)
PF10437
(Lip_prot_lig_C)
4 HIS A 146
ALA A 135
PHE A  98
GLY A 147
EDO  A 410 (-3.8A)
EDO  A 414 (-3.9A)
None
EDO  A 409 (-3.6A)
1.41A 1mj2D-1vqzA:
undetectable
1mj2D-1vqzA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wha KIAA0147 PROTEIN

(Homo sapiens)
PF00595
(PDZ)
4 HIS A  76
ALA A  25
PHE A  41
GLY A  27
HIS  A  76 ( 1.0A)
ALA  A  25 ( 0.0A)
PHE  A  41 ( 1.3A)
GLY  A  27 ( 0.0A)
1.20A 1mj2D-1whaA:
undetectable
1mj2D-1whaA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yq2 BETA-GALACTOSIDASE

(Arthrobacter
sp. C2-2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981)
4 HIS A 992
ALA A1008
PHE A1007
GLY A 993
None
1.32A 1mj2D-1yq2A:
undetectable
1mj2D-1yq2A:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z0u PROBABLE INORGANIC
POLYPHOSPHATE/ATP-NA
D KINASE


(Archaeoglobus
fulgidus)
PF01513
(NAD_kinase)
4 HIS A  78
ALA A  79
PHE A  84
GLY A  67
None
1.41A 1mj2D-1z0uA:
undetectable
1mj2D-1z0uA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zj9 PROBABLE
FERREDOXIN-DEPENDENT
NITRITE REDUCTASE
NIRA


(Mycobacterium
tuberculosis)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
4 HIS A 500
ALA A 543
PHE A 542
GLY A 499
None
1.12A 1mj2D-1zj9A:
undetectable
1mj2D-1zj9A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a19 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2
ALPHA SUBUNIT


(Saccharomyces
cerevisiae)
PF00575
(S1)
PF07541
(EIF_2_alpha)
4 HIS A 139
ALA A 140
PHE A 137
GLY A 138
None
1.28A 1mj2D-2a19A:
undetectable
1mj2D-2a19A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2av9 THIOESTERASE

(Pseudomonas
aeruginosa)
PF03061
(4HBT)
4 HIS A  30
ALA A  77
PHE A  78
GLY A  29
None
1.16A 1mj2D-2av9A:
undetectable
1mj2D-2av9A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cg5 L-AMINOADIPATE-SEMIA
LDEHYDE
DEHYDROGENASE-PHOSPH
OPANTETHEINYL
TRANSFERASE


(Homo sapiens)
PF01648
(ACPS)
4 HIS A 121
ALA A  69
PHE A  31
GLY A  73
COA  A1300 (-3.6A)
None
None
None
1.16A 1mj2D-2cg5A:
undetectable
1mj2D-2cg5A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dyq AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING
FAMILY B MEMBER 3


(Homo sapiens)
no annotation 4 HIS A 395
ALA A 396
PHE A 374
GLY A 398
None
1.20A 1mj2D-2dyqA:
undetectable
1mj2D-2dyqA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i1n DISCS, LARGE HOMOLOG
3


(Homo sapiens)
PF00595
(PDZ)
4 HIS A 196
ALA A 146
PHE A 161
GLY A 148
None
1.28A 1mj2D-2i1nA:
undetectable
1mj2D-2i1nA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jii SERINE/THREONINE-PRO
TEIN KINASE VRK3
MOLECULE: VACCINIA
RELATED KINASE 3


(Homo sapiens)
PF00069
(Pkinase)
4 HIS A 304
ALA A 330
PHE A 331
GLY A 305
None
1.37A 1mj2D-2jiiA:
undetectable
1mj2D-2jiiA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4f PROTEIN LAP4

(Homo sapiens)
PF00595
(PDZ)
4 HIS A 793
ALA A 743
PHE A 759
GLY A 745
EDO  A1821 ( 4.4A)
None
None
None
1.19A 1mj2D-2w4fA:
undetectable
1mj2D-2w4fA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wl7 DISKS LARGE HOMOLOG
2


(Mus musculus)
PF00595
(PDZ)
4 HIS A 165
ALA A 115
PHE A 130
GLY A 117
None
1.33A 1mj2D-2wl7A:
undetectable
1mj2D-2wl7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpi ANAPHASE-PROMOTING
COMPLEX SUBUNIT CUT9


(Schizosaccharomyces
pombe)
PF12895
(ANAPC3)
PF13181
(TPR_8)
PF13424
(TPR_12)
4 HIS A 415
ALA A 414
PHE A 413
GLY A 412
None
1.05A 1mj2D-2xpiA:
undetectable
1mj2D-2xpiA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xpi ANAPHASE-PROMOTING
COMPLEX SUBUNIT CUT9


(Schizosaccharomyces
pombe)
PF12895
(ANAPC3)
PF13181
(TPR_8)
PF13424
(TPR_12)
4 HIS A 415
ALA A 414
PHE A 417
GLY A 412
None
1.35A 1mj2D-2xpiA:
undetectable
1mj2D-2xpiA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ypj ENDOGLUCANASE CEL5A

([Eubacterium]
cellulosolvens)
no annotation 4 HIS A 596
ALA A 597
PHE A 599
GLY A 696
None
1.32A 1mj2D-2ypjA:
undetectable
1mj2D-2ypjA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zj8 PUTATIVE SKI2-TYPE
HELICASE


(Pyrococcus
furiosus)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF14520
(HHH_5)
4 HIS A 517
ALA A 574
PHE A 516
GLY A 514
None
1.34A 1mj2D-2zj8A:
undetectable
1mj2D-2zj8A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zsi PROBABLE GIBBERELLIN
RECEPTOR GID1L1


(Arabidopsis
thaliana)
PF07859
(Abhydrolase_3)
4 HIS A 119
ALA A 118
PHE A 117
GLY A 115
None
None
None
GA4  A 345 (-3.1A)
1.17A 1mj2D-2zsiA:
undetectable
1mj2D-2zsiA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0h PHOTOSYSTEM II CORE
LIGHT HARVESTING
PROTEIN


(Thermosynechococcus
vulcanus)
PF00421
(PSII)
4 HIS B 216
ALA B 212
PHE B 144
GLY B 140
None
1.25A 1mj2D-3a0hB:
undetectable
1mj2D-3a0hB:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9i HOMOCITRATE SYNTHASE

(Thermus
thermophilus)
PF00682
(HMGL-like)
4 HIS A 195
ALA A 164
PHE A 140
GLY A 196
LYS  A 378 ( 3.4A)
LYS  A 378 ( 3.9A)
None
None
1.30A 1mj2D-3a9iA:
undetectable
1mj2D-3a9iA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjr PUTATIVE
CARBOXYLESTERASE


(Lactobacillus
plantarum)
PF07859
(Abhydrolase_3)
4 HIS A  20
ALA A  58
PHE A  57
GLY A  61
None
0.85A 1mj2D-3bjrA:
undetectable
1mj2D-3bjrA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cv2 MALATE SYNTHASE A

(Escherichia
coli)
PF01274
(Malate_synthase)
4 HIS A 361
ALA A 326
PHE A 325
GLY A 363
None
1.37A 1mj2D-3cv2A:
undetectable
1mj2D-3cv2A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e03 SHORT CHAIN
DEHYDROGENASE


(Xanthomonas
campestris)
PF13561
(adh_short_C2)
4 HIS A 237
ALA A 180
PHE A 183
GLY A 184
None
1.39A 1mj2D-3e03A:
undetectable
1mj2D-3e03A:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3es1 CUPIN 2, CONSERVED
BARREL DOMAIN
PROTEIN


(Novosphingobium
aromaticivorans)
PF07883
(Cupin_2)
4 HIS A  20
ALA A  26
PHE A  28
GLY A  19
None
1.29A 1mj2D-3es1A:
undetectable
1mj2D-3es1A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f7m ALKALINE SERINE
PROTEASE VER112


(Lecanicillium
psalliotae)
PF00082
(Peptidase_S8)
4 HIS A 333
ALA A 307
PHE A 306
GLY A 309
None
1.27A 1mj2D-3f7mA:
undetectable
1mj2D-3f7mA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f7o SERINE PROTEASE

(Purpureocillium
lilacinum)
PF00082
(Peptidase_S8)
4 HIS A 232
ALA A 206
PHE A 205
GLY A 208
None
1.23A 1mj2D-3f7oA:
undetectable
1mj2D-3f7oA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gcw PROPROTEIN
CONVERTASE
SUBTILISIN/KEXIN
TYPE 9


(Homo sapiens)
PF00082
(Peptidase_S8)
4 HIS A 391
ALA A 363
PHE A 362
GLY A 365
None
1.26A 1mj2D-3gcwA:
undetectable
1mj2D-3gcwA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbc CHOLOYLGLYCINE
HYDROLASE


(Bacteroides
thetaiotaomicron)
PF02275
(CBAH)
4 HIS A  66
ALA A 120
PHE A 149
GLY A  65
GOL  A   5 (-4.7A)
None
None
None
1.33A 1mj2D-3hbcA:
undetectable
1mj2D-3hbcA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hl0 MALEYLACETATE
REDUCTASE


(Agrobacterium
fabrum)
PF00465
(Fe-ADH)
4 HIS A 263
ALA A 344
PHE A 345
GLY A 347
None
1.01A 1mj2D-3hl0A:
undetectable
1mj2D-3hl0A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ife PEPTIDASE T

(Bacillus
anthracis)
PF01546
(Peptidase_M20)
PF07687
(M20_dimer)
4 HIS A 165
ALA A 403
PHE A 406
GLY A 166
None
1.26A 1mj2D-3ifeA:
undetectable
1mj2D-3ifeA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ii7 KELCH-LIKE PROTEIN 7

(Homo sapiens)
PF01344
(Kelch_1)
4 HIS A 474
ALA A 485
PHE A 484
GLY A 475
None
1.36A 1mj2D-3ii7A:
undetectable
1mj2D-3ii7A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF7


(Schizosaccharomyces
pombe)
PF01423
(LSM)
4 HIS i 115
ALA i 119
PHE i 120
GLY i 116
None
1.33A 1mj2D-3jb9i:
undetectable
1mj2D-3jb9i:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ob8 BETA-GALACTOSIDASE

(Kluyveromyces
lactis)
PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
4 HIS A  72
ALA A 364
PHE A 361
GLY A 362
None
1.36A 1mj2D-3ob8A:
undetectable
1mj2D-3ob8A:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qh4 ESTERASE LIPW

(Mycobacterium
marinum)
PF07859
(Abhydrolase_3)
4 HIS A 305
ALA A 301
PHE A 300
GLY A 304
None
1.22A 1mj2D-3qh4A:
undetectable
1mj2D-3qh4A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubl GLUTATHIONE
TRANSFERASE


(Leptospira
interrogans)
PF13417
(GST_N_3)
4 HIS A 159
ALA A 158
PHE A 157
GLY A 156
None
1.24A 1mj2D-3ublA:
undetectable
1mj2D-3ublA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usc HYDROGENASE-1 LARGE
CHAIN


(Escherichia
coli)
PF00374
(NiFeSe_Hases)
4 HIS L 205
ALA L 204
PHE L 203
GLY L 202
None
1.21A 1mj2D-3uscL:
undetectable
1mj2D-3uscL:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdr ALCOHOL
DEHYDROGENASE DOMAIN
OF THE BIFUNCTIONAL
ACETALDEHYDE
DEHYDROGENASE


(Parageobacillus
thermoglucosidasius)
PF00465
(Fe-ADH)
4 HIS A 754
ALA A 865
PHE A 866
GLY A 868
None
0.89A 1mj2D-3zdrA:
undetectable
1mj2D-3zdrA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aq2 HOMOGENTISATE
1,2-DIOXYGENASE


(Pseudomonas
putida)
PF04209
(HgmA)
4 HIS A 265
ALA A  20
PHE A  19
GLY A 266
None
1.20A 1mj2D-4aq2A:
undetectable
1mj2D-4aq2A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c6o CAD PROTEIN

(Homo sapiens)
PF01979
(Amidohydro_1)
4 HIS A1687
ALA A1688
PHE A1704
GLY A1706
None
FMT  A2824 ( 3.6A)
None
None
1.23A 1mj2D-4c6oA:
undetectable
1mj2D-4c6oA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dzt AQUALYSIN-1

(Thermus
aquaticus)
PF00082
(Peptidase_S8)
4 HIS A 227
ALA A 199
PHE A 198
GLY A 201
None
1.33A 1mj2D-4dztA:
undetectable
1mj2D-4dztA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hfw 6-26 FAB HEAVY CHAIN

(Homo sapiens)
no annotation 4 HIS H  35
ALA H  97
PHE H 109
GLY H  99
None
1.27A 1mj2D-4hfwH:
undetectable
1mj2D-4hfwH:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hx0 PUTATIVE
NUCLEOTIDYLTRANSFERA
SE TM1012


(Thermotoga
maritima)
no annotation 4 HIS A  -4
ALA A  33
PHE A  32
GLY A  36
NA  A 202 (-3.8A)
NA  A 202 (-3.9A)
None
NA  A 202 ( 3.9A)
1.18A 1mj2D-4hx0A:
undetectable
1mj2D-4hx0A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jmj RNA/RNP
COMPLEX-1-INTERACTIN
G PHOSPHATASE


(Homo sapiens)
PF00782
(DSPc)
4 HIS A 105
ALA A 106
PHE A 110
GLY A 109
None
1.23A 1mj2D-4jmjA:
undetectable
1mj2D-4jmjA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kws D-MANNONATE
DEHYDRATASE


(Chromohalobacter
salexigens)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 HIS A 330
ALA A 367
PHE A 365
GLY A 326
None
1.16A 1mj2D-4kwsA:
undetectable
1mj2D-4kwsA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mda MARINER MOS1
TRANSPOSASE


(Drosophila
mauritiana)
PF01359
(Transposase_1)
4 HIS A 293
ALA A 289
PHE A 288
GLY A 292
None
1.18A 1mj2D-4mdaA:
undetectable
1mj2D-4mdaA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4og1 ENOYL-COA
HYDRATASE/ISOMERASE


(Novosphingobium
aromaticivorans)
PF00378
(ECH_1)
4 HIS A   7
ALA A  35
PHE A  37
GLY A  39
None
1.37A 1mj2D-4og1A:
undetectable
1mj2D-4og1A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oua LATENT FORM OF PPO4
TYROSINASE


(Agaricus
bisporus)
PF00264
(Tyrosinase)
4 HIS B  57
ALA B 270
PHE B 272
GLY B  58
CU1  B 601 (-3.1A)
None
None
NA  B 603 (-4.5A)
1.33A 1mj2D-4ouaB:
undetectable
1mj2D-4ouaB:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oua PROTEOLYTICALLY
ACTIVATED FORM OF
PPO4 TYROSINASE


(Agaricus
bisporus)
PF00264
(Tyrosinase)
4 HIS A  57
ALA A 270
PHE A 272
GLY A  58
CU1  A 401 (-3.2A)
None
None
NA  A 403 (-4.4A)
1.35A 1mj2D-4ouaA:
undetectable
1mj2D-4ouaA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ov6 PROPROTEIN
CONVERTASE
SUBTILISIN/KEXIN
TYPE 9


(Homo sapiens)
PF00082
(Peptidase_S8)
4 HIS B 391
ALA B 363
PHE B 362
GLY B 365
None
1.21A 1mj2D-4ov6B:
undetectable
1mj2D-4ov6B:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1


(Alicyclobacillus
acidocaldarius)
PF13416
(SBP_bac_8)
4 HIS A 177
ALA A 172
PHE A 171
GLY A 175
None
1.40A 1mj2D-4ovjA:
undetectable
1mj2D-4ovjA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p79 CLAUDIN-15

(Mus musculus)
PF00822
(PMP22_Claudin)
4 HIS A 124
ALA A 120
PHE A 180
GLY A 176
None
1.35A 1mj2D-4p79A:
undetectable
1mj2D-4p79A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pe5 GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B


(Rattus
norvegicus)
PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd)
4 HIS B 127
ALA B 100
PHE B  99
GLY B 128
None
1.17A 1mj2D-4pe5B:
undetectable
1mj2D-4pe5B:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3


(Thermobaculum
terrenum)
PF00271
(Helicase_C)
4 HIS A  98
ALA A  95
PHE A  94
GLY A  97
NI  A1001 (-3.4A)
None
None
None
0.74A 1mj2D-4q2cA:
undetectable
1mj2D-4q2cA:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qyr AT-LESS POLYKETIDE
SYNTHASE


(Streptomyces
platensis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc)
4 HIS A2807
ALA A2966
PHE A2961
GLY A2808
None
1.34A 1mj2D-4qyrA:
undetectable
1mj2D-4qyrA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2


(Pisum sativum)
PF00223
(PsaA_PsaB)
4 HIS B 389
ALA B 388
PHE B 387
GLY B 335
CLA  B1226 (-4.0A)
CLA  B1226 ( 4.2A)
BCR  B6010 ( 3.2A)
BCR  B6010 ( 4.3A)
1.06A 1mj2D-4rkuB:
undetectable
1mj2D-4rkuB:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzc FV M6P-1 HEAVY CHAIN

(Oryctolagus
cuniculus)
no annotation 4 HIS L  89
ALA L  34
PHE L  71
GLY L  90
None
1.31A 1mj2D-4rzcL:
undetectable
1mj2D-4rzcL:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wso PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE


(Burkholderia
thailandensis)
PF01467
(CTP_transf_like)
4 HIS A 157
ALA A 156
PHE A 155
GLY A 195
None
1.23A 1mj2D-4wsoA:
undetectable
1mj2D-4wsoA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywe PUTATIVE ALDEHYDE
DEHYDROGENASE


(Burkholderia
cenocepacia)
PF00171
(Aldedh)
4 HIS A 349
ALA A 348
PHE A 306
GLY A 350
None
1.39A 1mj2D-4yweA:
undetectable
1mj2D-4yweA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdn AT-LESS POLYKETIDE
SYNTHASE


(Streptomyces
platensis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc)
4 HIS A 823
ALA A 974
PHE A 969
GLY A 824
None
1.39A 1mj2D-4zdnA:
undetectable
1mj2D-4zdnA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a4j FORMATE--TETRAHYDROF
OLATE LIGASE


(Tepidanaerobacter
acetatoxydans)
PF01268
(FTHFS)
4 HIS A 279
ALA A 278
PHE A 274
GLY A 280
None
1.35A 1mj2D-5a4jA:
undetectable
1mj2D-5a4jA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a5g FORMATE--TETRAHYDROF
OLATE LIGASE


(Tepidanaerobacter
acetatoxydans)
PF01268
(FTHFS)
4 HIS A 278
ALA A 277
PHE A 273
GLY A 279
None
1.34A 1mj2D-5a5gA:
undetectable
1mj2D-5a5gA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5afe ENDOGLUCANASE CEL5A

([Eubacterium]
cellulosolvens)
no annotation 4 HIS A 596
ALA A 597
PHE A 599
GLY A 696
None
1.36A 1mj2D-5afeA:
undetectable
1mj2D-5afeA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cqr ELONGATOR COMPLEX
PROTEIN 1


(Homo sapiens)
PF04762
(IKI3)
4 HIS A1015
ALA A1010
PHE A1009
GLY A1013
None
1.41A 1mj2D-5cqrA:
undetectable
1mj2D-5cqrA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5de0 DEFERROCHELATASE

(Vibrio cholerae)
PF04261
(Dyp_perox)
4 HIS A 100
ALA A 101
PHE A  15
GLY A  13
None
0.83A 1mj2D-5de0A:
undetectable
1mj2D-5de0A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5et1 ESPIN

(Mus musculus)
PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5)
4 HIS A 317
ALA A 312
PHE A 314
GLY A 316
None
1.33A 1mj2D-5et1A:
undetectable
1mj2D-5et1A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5z ABC TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN


(Streptococcus
pneumoniae)
PF01547
(SBP_bac_1)
4 HIS A 340
ALA A 243
PHE A 242
GLY A 246
None
1.38A 1mj2D-5g5zA:
undetectable
1mj2D-5g5zA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5icl LIPOATE--PROTEIN
LIGASE


(Enterococcus
faecalis)
PF03099
(BPL_LplA_LipB)
PF10437
(Lip_prot_lig_C)
4 HIS A 147
ALA A 146
PHE A  86
GLY A 148
LAQ  A 401 (-3.7A)
None
None
LAQ  A 401 ( 3.8A)
1.26A 1mj2D-5iclA:
undetectable
1mj2D-5iclA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iuf BIFUNCTIONAL
OLIGORIBONUCLEASE
AND PAP PHOSPHATASE
NRNA


(Bacillus
subtilis)
PF01368
(DHH)
PF02272
(DHHA1)
4 HIS A 284
ALA A 287
PHE A 265
GLY A 283
A3P  A 402 (-3.7A)
A3P  A 401 ( 4.7A)
None
A3P  A 401 (-3.4A)
1.36A 1mj2D-5iufA:
undetectable
1mj2D-5iufA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jor FAB14.22 HEAVY CHAIN

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
4 HIS B  82
ALA B  67
PHE B  63
GLY B  65
None
1.25A 1mj2D-5jorB:
undetectable
1mj2D-5jorB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ns8 -

(-)
no annotation 4 HIS A 173
ALA A 169
PHE A 166
GLY A 172
None
1.33A 1mj2D-5ns8A:
undetectable
1mj2D-5ns8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opq 3,6-ANHYDRO-D-GALACT
OSIDASE


(Zobellia
galactanivorans)
no annotation 4 HIS A 518
ALA A 490
PHE A 489
GLY A 519
None
0.87A 1mj2D-5opqA:
undetectable
1mj2D-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ouo PERFORIN-LIKE
PROTEIN 1


(Toxoplasma
gondii)
no annotation 4 HIS A1061
ALA A 993
PHE A1058
GLY A 991
None
1.12A 1mj2D-5ouoA:
undetectable
1mj2D-5ouoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2


(Synechocystis
sp. PCC 6803)
no annotation 4 HIS b 387
ALA b 386
PHE b 385
GLY b 333
CLA  b1832 (-3.9A)
CLA  b1832 ( 3.9A)
BCR  b1848 ( 3.3A)
BCR  b1848 ( 4.4A)
1.11A 1mj2D-5oy0b:
undetectable
1mj2D-5oy0b:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tnx ALCOHOL
DEHYDROGENASE
ZINC-BINDING DOMAIN
PROTEIN


(Burkholderia
ambifaria)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 HIS A 139
ALA A  64
PHE A 142
GLY A 121
None
1.24A 1mj2D-5tnxA:
undetectable
1mj2D-5tnxA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpz GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B


(Rattus
norvegicus)
PF01094
(ANF_receptor)
4 HIS D 127
ALA D 100
PHE D  99
GLY D 128
None
1.33A 1mj2D-5tpzD:
undetectable
1mj2D-5tpzD:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uzu UNCHARACTERISED
PROTEIN


(Staphylococcus
aureus)
no annotation 4 HIS B  82
ALA B  77
PHE B  76
GLY B  80
None
1.09A 1mj2D-5uzuB:
undetectable
1mj2D-5uzuB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vlh PROPROTEIN
CONVERTASE
SUBTILISIN/KEXIN
TYPE 9


(Homo sapiens)
PF00082
(Peptidase_S8)
PF05922
(Inhibitor_I9)
4 HIS A 391
ALA A 363
PHE A 362
GLY A 365
None
1.28A 1mj2D-5vlhA:
undetectable
1mj2D-5vlhA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vwk PROTEIN SCRIBBLE
HOMOLOG


(Homo sapiens)
no annotation 4 HIS A 793
ALA A 743
PHE A 759
GLY A 745
None
1.18A 1mj2D-5vwkA:
undetectable
1mj2D-5vwkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wou PROTEIN LAP4

(Drosophila
melanogaster)
no annotation 4 HIS A  71
ALA A  21
PHE A  37
GLY A  23
EDO  A 105 (-4.1A)
None
None
EDO  A 103 (-3.7A)
1.21A 1mj2D-5wouA:
undetectable
1mj2D-5wouA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wsl KERATINASE

(Meiothermus
taiwanensis)
no annotation 4 HIS A 229
ALA A 201
PHE A 200
GLY A 203
None
1.24A 1mj2D-5wslA:
undetectable
1mj2D-5wslA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x03 HTH-TYPE
TRANSCRIPTIONAL
REGULATORY PROTEIN
GABR


(Bacillus
subtilis)
PF00155
(Aminotran_1_2)
4 HIS A 417
ALA A 467
PHE A 465
GLY A 470
None
1.31A 1mj2D-5x03A:
undetectable
1mj2D-5x03A:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x33 LTB4
RECEPTOR,LYSOZYME,LT
B4 RECEPTOR


(Cavia
porcellus;
Escherichia
virus T4)
no annotation 4 HIS A 240
ALA A 188
PHE A 186
GLY A 191
None
1.37A 1mj2D-5x33A:
undetectable
1mj2D-5x33A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6azp STAPHYLOCOCCAL
PEROXIDASE INHIBITOR


(Staphylococcus
aureus)
no annotation 4 HIS B  82
ALA B  77
PHE B  76
GLY B  80
None
1.04A 1mj2D-6azpB:
undetectable
1mj2D-6azpB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c2h CYSTATHIONINE
BETA-SYNTHASE


(Saccharomyces
cerevisiae)
no annotation 4 HIS A 167
ALA A 166
PHE A 169
GLY A 203
None
PGE  A 409 ( 4.3A)
PGE  A 409 (-4.2A)
None
1.06A 1mj2D-6c2hA:
undetectable
1mj2D-6c2hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c5c 3-DEHYDROQUINATE
SYNTHASE


(Candida
albicans)
no annotation 4 HIS A 165
ALA A 122
PHE A 125
GLY A 128
None
1.33A 1mj2D-6c5cA:
undetectable
1mj2D-6c5cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d7a PERFORIN-LIKE
PROTEIN 1


(Toxoplasma
gondii)
no annotation 4 HIS A1074
ALA A1006
PHE A1071
GLY A1004
None
1.21A 1mj2D-6d7aA:
undetectable
1mj2D-6d7aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fos PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2


(Cyanidioschyzon
merolae)
no annotation 4 HIS B 387
ALA B 386
PHE B 385
GLY B 333
CLA  B1226 (-4.1A)
CLA  B1226 ( 4.4A)
BCR  B4008 (-4.8A)
BCR  B4008 ( 4.6A)
1.39A 1mj2D-6fosB:
undetectable
1mj2D-6fosB:
undetectable