SIMILAR PATTERNS OF AMINO ACIDS FOR 1MEI_A_MOAA600_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1eep INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE


(Borreliella
burgdorferi)
PF00478
(IMPDH)
4 ASP A 172
SER A 173
ASN A 201
ILE A 223
None
0.59A 1meiA-1eepA:
44.3
1meiA-1eepA:
33.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fwx NITROUS OXIDE
REDUCTASE


(Paracoccus
denitrificans)
PF13473
(Cupredoxin_1)
4 SER A 138
ASN A 139
GLU A  87
GLY A  88
None
0.66A 1meiA-1fwxA:
undetectable
1meiA-1fwxA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gpe PROTEIN (GLUCOSE
OXIDASE)


(Penicillium
amagasakiense)
PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C)
4 SER A 107
ASN A 111
ILE A 110
GLY A  32
FAD  A 600 (-3.4A)
FAD  A 600 (-3.9A)
None
FAD  A 600 ( 4.6A)
0.94A 1meiA-1gpeA:
undetectable
1meiA-1gpeA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ia5 POLYGALACTURONASE

(Aspergillus
aculeatus)
PF00295
(Glyco_hydro_28)
4 SER A 274
SER A 275
ASN A 269
ILE A 240
None
1.00A 1meiA-1ia5A:
undetectable
1meiA-1ia5A:
21.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jcn INOSINE
MONOPHOSPHATE
DEHYDROGENASE I


(Homo sapiens)
PF00478
(IMPDH)
PF00571
(CBS)
4 ASP A 274
SER A 275
SER A 276
ASN A 303
None
None
None
CPR  A 631 ( 4.5A)
0.30A 1meiA-1jcnA:
40.6
1meiA-1jcnA:
35.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jeo HYPOTHETICAL PROTEIN
MJ1247


(Methanocaldococcus
jannaschii)
PF01380
(SIS)
4 SER A  11
ASN A  13
ILE A  14
GLU A   6
None
0.96A 1meiA-1jeoA:
undetectable
1meiA-1jeoA:
16.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jr1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2


(Cricetulus
griseus)
PF00478
(IMPDH)
PF00571
(CBS)
4 ASP A 274
SER A 275
ASN A 303
GLY A 415
MOA  A1332 (-3.5A)
None
MOA  A1332 (-3.7A)
IMP  A1331 ( 3.1A)
0.91A 1meiA-1jr1A:
48.3
1meiA-1jr1A:
32.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jr1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2


(Cricetulus
griseus)
PF00478
(IMPDH)
PF00571
(CBS)
4 ASP A 274
SER A 276
ASN A 303
GLY A 415
MOA  A1332 (-3.5A)
MOA  A1332 (-2.6A)
MOA  A1332 (-3.7A)
IMP  A1331 ( 3.1A)
0.40A 1meiA-1jr1A:
48.3
1meiA-1jr1A:
32.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lo3 IG GAMMA 2A HEAVY
CHAIN


(Mus musculus)
no annotation 4 SER Y  25
ASN Y  79
ILE Y  80
GLY Y 110
None
0.74A 1meiA-1lo3Y:
undetectable
1meiA-1lo3Y:
19.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lrt INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Tritrichomonas
suis)
PF00478
(IMPDH)
7 ASP A 261
SER A 262
SER A 263
ASN A 291
ILE A 313
GLU A 408
GLY A 409
TAD  A 901 (-2.3A)
TAD  A 901 ( 2.6A)
TAD  A 901 (-2.7A)
IMP  A 801 ( 4.6A)
TAD  A 901 (-4.1A)
None
IMP  A 801 ( 3.2A)
0.33A 1meiA-1lrtA:
58.5
1meiA-1lrtA:
74.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lrt INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Tritrichomonas
suis)
PF00478
(IMPDH)
4 SER A 263
ASN A 291
GLU A 408
GLY A 407
TAD  A 901 (-2.7A)
IMP  A 801 ( 4.6A)
None
IMP  A 801 (-3.2A)
0.91A 1meiA-1lrtA:
58.5
1meiA-1lrtA:
74.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m1j FIBRINOGEN BETA
CHAIN


(Gallus gallus)
PF00147
(Fibrinogen_C)
PF08702
(Fib_alpha)
4 SER B 455
ILE B 257
GLU B 295
GLY B 294
None
0.94A 1meiA-1m1jB:
undetectable
1meiA-1m1jB:
24.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mew INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Tritrichomonas
suis)
PF00478
(IMPDH)
PF00571
(CBS)
4 ASP A 261
GLU A 408
GLY A 409
ARG A 414
NAD  A 987 (-2.5A)
NAD  A 987 ( 4.9A)
XMP  A 602 ( 3.1A)
None
0.87A 1meiA-1mewA:
61.9
1meiA-1mewA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mew INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Tritrichomonas
suis)
PF00478
(IMPDH)
PF00571
(CBS)
7 ASP A 261
SER A 262
SER A 263
ASN A 291
ILE A 313
GLU A 408
GLY A 409
NAD  A 987 (-2.5A)
NAD  A 987 (-2.7A)
NAD  A 987 (-3.1A)
XMP  A 602 ( 4.4A)
NAD  A 987 (-4.5A)
NAD  A 987 ( 4.9A)
XMP  A 602 ( 3.1A)
0.27A 1meiA-1mewA:
61.9
1meiA-1mewA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mew INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Tritrichomonas
suis)
PF00478
(IMPDH)
PF00571
(CBS)
4 SER A 263
ASN A 291
GLU A 408
GLY A 407
NAD  A 987 (-3.1A)
XMP  A 602 ( 4.4A)
NAD  A 987 ( 4.9A)
XMP  A 602 (-3.3A)
0.83A 1meiA-1mewA:
61.9
1meiA-1mewA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mox EPIDERMAL GROWTH
FACTOR RECEPTOR


(Homo sapiens)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
4 SER A 326
ASN A 328
ILE A 332
GLY A 315
None
NAG  A 650 (-1.9A)
None
None
0.81A 1meiA-1moxA:
undetectable
1meiA-1moxA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o60 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE


(Haemophilus
influenzae)
PF00793
(DAHP_synth_1)
4 ASP A 199
ASN A 136
ILE A 111
GLY A  24
None
0.98A 1meiA-1o60A:
12.1
1meiA-1o60A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wf3 GTP-BINDING PROTEIN

(Thermus
thermophilus)
PF01926
(MMR_HSR1)
PF07650
(KH_2)
4 SER A   7
ILE A  49
GLY A  53
ARG A  54
None
0.83A 1meiA-1wf3A:
undetectable
1meiA-1wf3A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wn1 DIPEPTIDASE

(Pyrococcus
horikoshii)
PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
4 ASP A 105
ILE A  43
GLU A  39
GLY A  38
None
0.88A 1meiA-1wn1A:
undetectable
1meiA-1wn1A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xz9 AFADIN

(Homo sapiens)
PF00595
(PDZ)
4 SER A  44
SER A  26
ILE A  27
GLY A  49
None
1.00A 1meiA-1xz9A:
undetectable
1meiA-1xz9A:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yf2 TYPE I
RESTRICTION-MODIFICA
TION ENZYME, S
SUBUNIT


(Methanocaldococcus
jannaschii)
PF01420
(Methylase_S)
4 ASP A 265
ASN A 259
ILE A 258
GLU A 279
None
0.79A 1meiA-1yf2A:
undetectable
1meiA-1yf2A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2atm HYALURONOGLUCOSAMINI
DASE


(Vespula
vulgaris)
PF01630
(Glyco_hydro_56)
4 SER A 248
ASN A 250
ILE A 247
GLY A 289
None
0.95A 1meiA-2atmA:
5.3
1meiA-2atmA:
19.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2cu0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Pyrococcus
horikoshii)
PF00478
(IMPDH)
PF00571
(CBS)
4 ASP A 247
ASN A 275
ILE A 295
GLY A 385
None
XMP  A1001 ( 4.4A)
None
XMP  A1001 (-3.1A)
0.44A 1meiA-2cu0A:
47.5
1meiA-2cu0A:
33.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0v METHANOL
DEHYDROGENASE LARGE
SUBUNIT


(Hyphomicrobium
denitrificans)
PF01011
(PQQ)
PF13360
(PQQ_2)
4 SER A  69
SER A  70
ASN A 108
GLY A 536
None
0.81A 1meiA-2d0vA:
undetectable
1meiA-2d0vA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d7u ADENYLOSUCCINATE
SYNTHETASE


(Pyrococcus
horikoshii)
PF00709
(Adenylsucc_synt)
4 SER A 223
ILE A 323
GLU A  14
GLY A  15
None
0.87A 1meiA-2d7uA:
undetectable
1meiA-2d7uA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hal HEPATITIS A PROTEASE
3C


(Hepatovirus A)
PF00548
(Peptidase_C3)
4 SER A 178
SER A 179
GLU A 132
GLY A 133
None
0.68A 1meiA-2halA:
undetectable
1meiA-2halA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p9b POSSIBLE PROLIDASE

(Bifidobacterium
longum)
PF01979
(Amidohydro_1)
4 SER A 225
ILE A 168
GLU A 251
GLY A 252
None
0.95A 1meiA-2p9bA:
5.2
1meiA-2p9bA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qj8 MLR6093 PROTEIN

(Mesorhizobium
japonicum)
PF04952
(AstE_AspA)
4 ASN A  87
ILE A  86
GLU A 119
GLY A 111
None
0.96A 1meiA-2qj8A:
undetectable
1meiA-2qj8A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z61 PROBABLE ASPARTATE
AMINOTRANSFERASE 2


(Methanocaldococcus
jannaschii)
PF00155
(Aminotran_1_2)
4 SER A 236
ASN A  91
ILE A 241
GLU A 212
None
0.72A 1meiA-2z61A:
undetectable
1meiA-2z61A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zws NEUTRAL CERAMIDASE

(Pseudomonas
aeruginosa)
PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C)
4 SER A 464
ILE A 326
GLU A 459
ARG A 160
None
None
None
ZN  A 647 ( 4.3A)
0.87A 1meiA-2zwsA:
undetectable
1meiA-2zwsA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aat ASPARTATE
AMINOTRANSFERASE


(Escherichia
coli)
PF00155
(Aminotran_1_2)
4 SER A 255
SER A 257
ASN A 259
GLY A 302
PLP  A 410 (-2.4A)
PLP  A 410 (-3.2A)
None
None
0.99A 1meiA-3aatA:
undetectable
1meiA-3aatA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3clh 3-DEHYDROQUINATE
SYNTHASE


(Helicobacter
pylori)
PF01761
(DHQ_synthase)
4 SER A 206
ASN A 208
ILE A 209
GLU A 201
None
0.90A 1meiA-3clhA:
2.5
1meiA-3clhA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ekg MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME


(Azotobacter
vinelandii)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 ASN A 125
ILE A 124
GLU A 270
GLY A 269
None
None
MG  A 601 ( 2.4A)
None
0.69A 1meiA-3ekgA:
10.3
1meiA-3ekgA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3faw RETICULOCYTE BINDING
PROTEIN


(Streptococcus
agalactiae)
PF00128
(Alpha-amylase)
PF02922
(CBM_48)
4 ASP A1079
ASN A1099
ILE A1148
GLY A1073
None
0.75A 1meiA-3fawA:
undetectable
1meiA-3fawA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3htn PUTATIVE DNA BINDING
PROTEIN


(Bacteroides
thetaiotaomicron)
PF03479
(DUF296)
4 SER A  81
ASN A 120
ILE A 121
GLY A  84
None
0.96A 1meiA-3htnA:
undetectable
1meiA-3htnA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ing HOMOSERINE
DEHYDROGENASE


(Thermoplasma
acidophilum)
PF00742
(Homoserine_dh)
PF03447
(NAD_binding_3)
4 SER A 171
SER A 172
ASN A 175
GLY A 146
None
None
None
NDP  A 326 (-3.9A)
1.01A 1meiA-3ingA:
undetectable
1meiA-3ingA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4j TRANSLATION
INITIATION FACTOR
IF-2


(Thermus
thermophilus)
PF00009
(GTP_EFTU)
PF04760
(IF2_N)
PF11987
(IF-2)
4 SER A 254
ASN A 265
ILE A 251
GLY A 410
None
0.80A 1meiA-3j4jA:
undetectable
1meiA-3j4jA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4u MAJOR CAPSID PROTEIN

(Bordetella
virus BPP1)
no annotation 4 SER A 136
SER A 135
GLY A 144
ARG A 148
None
0.93A 1meiA-3j4uA:
undetectable
1meiA-3j4uA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)


(Helicobacter
pylori)
PF00483
(NTP_transferase)
4 SER A  87
ASN A  90
ILE A  91
ARG A 272
None
0.86A 1meiA-3jujA:
undetectable
1meiA-3jujA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ku0 RIBOSOME-INACTIVATIN
G PROTEIN GELONIN


(Suregada
multiflora)
PF00161
(RIP)
4 SER A  34
ASN A  33
ILE A  37
GLY A 209
None
0.99A 1meiA-3ku0A:
undetectable
1meiA-3ku0A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nf4 ACYL-COA
DEHYDROGENASE


(Mycolicibacterium
thermoresistibile)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
4 SER A 321
ILE A 322
GLU A 367
GLY A 368
None
None
None
FAD  A 384 ( 4.4A)
0.84A 1meiA-3nf4A:
undetectable
1meiA-3nf4A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3njp EPIDERMAL GROWTH
FACTOR RECEPTOR


(Homo sapiens)
PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV)
4 SER A 326
ASN A 328
ILE A 332
GLY A 315
None
NAG  A1328 (-1.7A)
None
None
0.86A 1meiA-3njpA:
undetectable
1meiA-3njpA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o5c CYTOCHROME C551
PEROXIDASE


(Shewanella
oneidensis)
PF00034
(Cytochrom_C)
PF03150
(CCP_MauG)
4 ASP A  72
ASN A  88
ILE A  87
GLY A  79
None
CA  A 601 (-2.9A)
HEM  A 401 (-4.4A)
HEM  A 401 ( 3.8A)
1.01A 1meiA-3o5cA:
undetectable
1meiA-3o5cA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oz7 PHOSPHOGLYCERATE
KINASE


(Plasmodium
falciparum)
PF00162
(PGK)
4 SER A 185
ASN A 162
ILE A 161
GLU A 192
None
1.00A 1meiA-3oz7A:
undetectable
1meiA-3oz7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdq ALPHA-BISABOLENE
SYNTHASE


(Abies grandis)
PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C)
4 SER A 729
SER A 730
GLU A 644
GLY A 663
None
0.95A 1meiA-3sdqA:
undetectable
1meiA-3sdqA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sl1 ARGINASE

(Plasmodium
falciparum)
PF00491
(Arginase)
4 ASP A 325
SER A 326
ILE A 291
GLY A 219
MN  A 412 ( 2.0A)
None
None
None
0.73A 1meiA-3sl1A:
undetectable
1meiA-3sl1A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suc PRENECK APPENDAGE
PROTEIN


(Bacillus virus
phi29)
PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3)
4 SER A 491
ASN A 519
ILE A 518
GLY A 468
None
0.68A 1meiA-3sucA:
undetectable
1meiA-3sucA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tix CHROMO
DOMAIN-CONTAINING
PROTEIN 1
UBIQUITIN-LIKE
PROTEIN
SMT3,RNA-INDUCED
TRANSCRIPTIONAL
SILENCING COMPLEX
PROTEIN TAS3


(Saccharomyces
cerevisiae;
Schizosaccharomyces
pombe)
PF11976
(Rad60-SLD)
no annotation
4 SER B 706
ASN B 744
GLU A  63
GLY A -33
None
0.92A 1meiA-3tixB:
undetectable
1meiA-3tixB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w08 ALDOXIME DEHYDRATASE

(Pseudomonas
chlororaphis)
PF13816
(Dehydratase_hem)
4 SER A   3
ILE A 166
GLU A  21
ARG A  13
None
0.92A 1meiA-3w08A:
undetectable
1meiA-3w08A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wsv L-LACTATE
DEHYDROGENASE


(Enterococcus
mundtii)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 SER A 122
ASN A  98
ILE A 101
GLY A  14
None
0.98A 1meiA-3wsvA:
undetectable
1meiA-3wsvA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E


(Streptomyces
cinnabarigriseus)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 SER A  72
SER A  73
ILE A  74
GLU A 194
None
0.91A 1meiA-4a0sA:
undetectable
1meiA-4a0sA:
19.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4af0 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Cryptococcus
neoformans)
PF00478
(IMPDH)
PF00571
(CBS)
5 ASP B 288
SER B 289
SER B 290
ASN B 317
GLY B 429
MOA  B1526 (-3.3A)
MOA  B1526 (-3.9A)
MOA  B1526 (-2.6A)
MOA  B1526 ( 3.6A)
IMP  B1527 ( 3.3A)
0.32A 1meiA-4af0B:
48.1
1meiA-4af0B:
33.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwq TRNA-SPLICING LIGASE
RTCB


(Pyrococcus
horikoshii)
PF01139
(RtcB)
4 SER A  88
SER A 270
ILE A 256
GLY A  85
None
0.67A 1meiA-4dwqA:
undetectable
1meiA-4dwqA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fwt ELONGATION FACTOR
TS, ELONGATION
FACTOR TU, LINKER, Q
BETA REPLICASE


(Escherichia
coli;
Escherichia
virus Qbeta)
PF00009
(GTP_EFTU)
PF00889
(EF_TS)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2)
PF03431
(RNA_replicase_B)
4 ASP A 621
ILE A 532
GLY A 624
ARG A 612
None
0.94A 1meiA-4fwtA:
undetectable
1meiA-4fwtA:
17.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fxs INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Vibrio cholerae)
PF00478
(IMPDH)
PF00571
(CBS)
5 SER A 251
SER A 252
ASN A 279
ILE A 301
GLY A 391
MOA  A 702 (-3.7A)
MOA  A 702 (-2.8A)
MOA  A 702 (-3.5A)
MOA  A 702 (-4.1A)
IMP  A 701 (-3.2A)
0.47A 1meiA-4fxsA:
49.7
1meiA-4fxsA:
36.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hfu FAB 8M2 HEAVY CHAIN

(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
4 SER H  30
ILE H  51
GLU H  98
GLY H  97
None
0.96A 1meiA-4hfuH:
undetectable
1meiA-4hfuH:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i5j SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
REGULATORY SUBUNIT
B'' SUBUNIT ALPHA


(Homo sapiens)
PF13499
(EF-hand_7)
4 ASP A 196
ILE A 249
GLU A 193
GLY A 242
None
0.83A 1meiA-4i5jA:
undetectable
1meiA-4i5jA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9u L-LACTATE
DEHYDROGENASE A
CHAIN


(Oryctolagus
cuniculus)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 SER A 136
ASN A 112
ILE A 115
GLY A  28
None
None
1E7  A 401 (-4.2A)
None
1.01A 1meiA-4i9uA:
undetectable
1meiA-4i9uA:
21.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ix2 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Vibrio cholerae)
PF00478
(IMPDH)
5 ASP A 250
SER A 251
SER A 252
ASN A 279
ILE A 301
None
None
None
IMP  A 501 ( 4.4A)
None
0.83A 1meiA-4ix2A:
45.5
1meiA-4ix2A:
31.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ixo NIFS-LIKE PROTEIN

(Rickettsia
africae)
PF00266
(Aminotran_5)
4 SER A 348
ASN A 287
ILE A 258
GLY A 198
None
0.88A 1meiA-4ixoA:
undetectable
1meiA-4ixoA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lu0 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE


(Pseudomonas
aeruginosa)
PF00793
(DAHP_synth_1)
4 ASP A 203
ASN A 142
ILE A 117
GLY A  30
None
0.94A 1meiA-4lu0A:
12.1
1meiA-4lu0A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Campylobacter
jejuni)
PF00478
(IMPDH)
4 ASP A 244
SER A 245
ILE A 295
GLY A 385
None
None
None
IMP  A 500 ( 3.3A)
0.87A 1meiA-4mz1A:
49.7
1meiA-4mz1A:
29.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mz1 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Campylobacter
jejuni)
PF00478
(IMPDH)
4 SER A 245
ASN A 273
ILE A 295
GLY A 385
None
IMP  A 500 ( 4.1A)
None
IMP  A 500 ( 3.3A)
0.53A 1meiA-4mz1A:
49.7
1meiA-4mz1A:
29.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9g ANTIBODY 17HD9,
HEAVY CHAIN


(Macaca mulatta)
PF07654
(C1-set)
PF07686
(V-set)
4 ASN A  60
ILE A  48
GLY A 100
ARG A 100
None
0.96A 1meiA-4n9gA:
undetectable
1meiA-4n9gA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE


(Pseudomonas
syringae group
genomosp. 3)
PF13229
(Beta_helix)
4 ASP A 331
SER A 357
ILE A 381
GLY A 334
MLY  A 356 ( 3.7A)
MLY  A 356 ( 4.5A)
None
None
0.83A 1meiA-4nk6A:
undetectable
1meiA-4nk6A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nru RNA DEPENDENT RNA
POLYMERASE


(Norwalk virus)
PF00680
(RdRP_1)
4 SER A  71
ILE A 292
GLU A 296
GLY A 297
None
0.92A 1meiA-4nruA:
undetectable
1meiA-4nruA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ogc HNH ENDONUCLEASE
DOMAIN PROTEIN


(Actinomyces
naeslundii)
PF01844
(HNH)
4 SER A1005
ASN A1002
ILE A1001
GLY A1012
None
0.91A 1meiA-4ogcA:
undetectable
1meiA-4ogcA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ozy POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE


(Pseudomonas
syringae group
genomosp. 3)
PF13229
(Beta_helix)
4 ASP A 331
SER A 357
ILE A 381
GLY A 334
MLY  A 356 ( 3.5A)
MLY  A 356 ( 4.6A)
None
None
0.80A 1meiA-4ozyA:
undetectable
1meiA-4ozyA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppz SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE


(Neisseria
meningitidis)
PF01546
(Peptidase_M20)
PF07687
(M20_dimer)
4 ASP A  70
SER A 133
ILE A  52
GLU A 135
None
None
None
ZN  A 601 (-3.9A)
0.96A 1meiA-4ppzA:
undetectable
1meiA-4ppzA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6u UNCHARACTERIZED
PROTEIN


(Mycobacterium
tuberculosis)
no annotation 4 SER A 122
ILE A 179
GLU A 117
GLY A 101
1PE  A 401 (-3.2A)
None
None
None
0.97A 1meiA-4q6uA:
undetectable
1meiA-4q6uA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qa9 EPOXIDE HYDROLASE

(Streptomyces
carzinostaticus)
PF06441
(EHN)
4 ASP A 346
SER A 204
ASN A 202
ILE A 316
EDO  A 405 (-3.2A)
None
EDO  A 405 (-4.7A)
None
0.88A 1meiA-4qa9A:
undetectable
1meiA-4qa9A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u8t ZYRO0G01672P

(Zygosaccharomyces
rouxii)
PF04146
(YTH)
4 SER A 194
ASN A 197
ILE A 199
GLU A 189
None
0.94A 1meiA-4u8tA:
undetectable
1meiA-4u8tA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wa0 POSSIBLE ADHESIN

(Caldicellulosiruptor
kronotskyensis)
no annotation 4 ASP A 473
SER A 477
ILE A 508
GLY A 497
MG  A 601 (-3.3A)
None
None
None
0.62A 1meiA-4wa0A:
undetectable
1meiA-4wa0A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A


(Pseudomonas
aeruginosa)
PF01425
(Amidase)
4 ASP A 209
ILE A 310
GLY A 175
ARG A 178
None
0.94A 1meiA-4wj3A:
undetectable
1meiA-4wj3A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wpg DTDP-4-DEHYDRORHAMNO
SE REDUCTASE


(Streptococcus
pyogenes)
PF04321
(RmlD_sub_bind)
4 SER A  82
ASN A  84
ILE A  36
GLU A  75
None
0.97A 1meiA-4wpgA:
undetectable
1meiA-4wpgA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhb SIALIDASE B

(Streptococcus
pneumoniae)
PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2)
4 SER A  91
ILE A 183
GLU A 194
GLY A 195
None
0.93A 1meiA-4xhbA:
undetectable
1meiA-4xhbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xwu INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE


(Eremothecium
gossypii)
PF00478
(IMPDH)
4 ASP A 277
SER A 278
SER A 279
ASN A 306
None
0.22A 1meiA-4xwuA:
38.9
1meiA-4xwuA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z61 PHYTOSULFOKINE
RECEPTOR 1


(Daucus carota)
PF00560
(LRR_1)
PF13855
(LRR_8)
4 SER A 143
SER A 142
ASN A 167
GLY A  94
None
None
None
NAG  A 701 ( 3.7A)
0.98A 1meiA-4z61A:
undetectable
1meiA-4z61A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b1h CYSTATHIONINE
BETA-SYNTHASE


(Lactobacillus
plantarum)
PF00291
(PALP)
4 ASP A 290
SER A 291
SER A 292
GLY A 265
LLP  A  42 ( 3.2A)
None
None
None
0.83A 1meiA-5b1hA:
undetectable
1meiA-5b1hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gr8 LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE PEPR1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8)
4 SER A 422
ASN A 445
GLU A 378
GLY A 377
None
0.93A 1meiA-5gr8A:
undetectable
1meiA-5gr8A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1k GEM-ASSOCIATED
PROTEIN 5


(Homo sapiens)
PF00400
(WD40)
PF12894
(ANAPC4_WD40)
4 SER A 604
ASN A 605
GLU A 541
GLY A 554
None
A  C  10 ( 3.7A)
None
None
0.92A 1meiA-5h1kA:
undetectable
1meiA-5h1kA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ie9 NUCLEOTIDE
PYROPHOSPHOHYDROLASE


(Bacillus cereus)
PF03819
(MazG)
4 ASP A  14
SER A  80
ASN A  82
GLY A  23
None
0.92A 1meiA-5ie9A:
undetectable
1meiA-5ie9A:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j72 PUTATIVE
N-ACETYLMURAMOYL-L-A
LANINE
AMIDASE,AUTOLYSIN
CWP6


(Clostridioides
difficile)
PF01520
(Amidase_3)
PF04122
(CW_binding_2)
4 ASP A 249
ILE A 180
GLU A 252
GLY A 246
None
0.94A 1meiA-5j72A:
undetectable
1meiA-5j72A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjp NONRIBOSOMAL PEPTIDE
SYNTHASE


(Streptomyces
sp. MJ635-86F5)
PF00501
(AMP-binding)
4 SER A 184
ASN A 188
ILE A 189
GLY A  92
None
1.00A 1meiA-5jjpA:
undetectable
1meiA-5jjpA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE


(Porphyromonas
gingivalis)
PF10459
(Peptidase_S46)
4 ILE A 345
GLU A 676
GLY A 677
ARG A 673
None
0.96A 1meiA-5jwfA:
undetectable
1meiA-5jwfA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE


(Porphyromonas
endodontalis)
PF10459
(Peptidase_S46)
4 ILE A 344
GLU A 673
GLY A 674
ARG A 670
None
0.88A 1meiA-5jxkA:
undetectable
1meiA-5jxkA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jz8 ASPARTYL/ASPARAGINYL
BETA-HYDROXYLASE


(Homo sapiens)
PF05118
(Asp_Arg_Hydrox)
PF13181
(TPR_8)
PF13432
(TPR_16)
4 ASP A 721
SER A 722
SER A 563
ARG A 662
OGA  A 802 ( 4.8A)
None
None
None
0.95A 1meiA-5jz8A:
undetectable
1meiA-5jz8A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ko5 PURINE NUCLEOSIDE
PHOSPHORYLASE


(Schistosoma
mansoni)
PF01048
(PNP_UDP_1)
4 SER A 241
ILE A 243
GLY A  34
ARG A  86
None
None
EDO  A 302 (-3.4A)
EDO  A 302 (-4.3A)
0.97A 1meiA-5ko5A:
undetectable
1meiA-5ko5A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ks8 PYRUVATE CARBOXYLASE
SUBUNIT ALPHA


(Methylobacillus
flagellatus)
PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
4 ILE A 354
GLU A  12
GLY A  11
ARG A  10
None
0.97A 1meiA-5ks8A:
undetectable
1meiA-5ks8A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l39 RMM MICROCOMPARTMENT
SHELL PROTEIN
MSM0275


(Mycolicibacterium
smegmatis)
PF00936
(BMC)
4 SER A 147
ILE A 150
GLU A  68
GLY A  72
None
0.94A 1meiA-5l39A:
undetectable
1meiA-5l39A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqm GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN


(Bacteroides
thetaiotaomicron)
PF17132
(Glyco_hydro_106)
4 ASP A 547
SER A 696
ILE A 697
GLY A 581
None
0.96A 1meiA-5mqmA:
3.7
1meiA-5mqmA:
19.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tc3 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE


(Eremothecium
gossypii)
PF00478
(IMPDH)
PF00571
(CBS)
5 ASP A 277
SER A 278
SER A 279
ASN A 306
GLY A 418
None
None
None
5GP  A 600 (-3.2A)
5GP  A 600 (-3.1A)
0.58A 1meiA-5tc3A:
46.0
1meiA-5tc3A:
34.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7a ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT


(Oryctolagus
cuniculus)
no annotation 4 ASP B 296
ASN B 335
ILE B 336
GLY B 340
None
None
None
FTT  B 609 ( 3.3A)
0.88A 1meiA-5w7aB:
undetectable
1meiA-5w7aB:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7c ACYLOXYACYL
HYDROLASE


(Homo sapiens)
no annotation 4 ASP C 297
ASN C 336
ILE C 337
GLY C 341
None
None
None
FTT  C 610 ( 3.1A)
0.87A 1meiA-5w7cC:
undetectable
1meiA-5w7cC:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yww NUCLEOTIDE BINDING
PROTEIN PINC


(Sulfolobus
islandicus)
no annotation 4 ASP A 373
ILE A 253
GLU A 249
GLY A 342
None
0.91A 1meiA-5ywwA:
undetectable
1meiA-5ywwA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE


(Acinetobacter
baumannii)
no annotation 4 ASP A 201
ASN A 140
ILE A 115
GLY A  28
None
0.99A 1meiA-6bngA:
7.3
1meiA-6bngA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c90 EXOSOME RNA HELICASE
MTR4,EXOSOME RNA
HELICASE MTR4


(Homo sapiens)
no annotation 4 SER A 513
SER A 514
ILE A 518
GLY A 548
None
0.95A 1meiA-6c90A:
undetectable
1meiA-6c90A:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6caj TRANSLATION
INITIATION FACTOR
EIF-2B SUBUNIT BETA


(Homo sapiens)
no annotation 4 ASP C 219
ILE C 234
GLU C 193
GLY C 200
None
0.84A 1meiA-6cajC:
undetectable
1meiA-6cajC:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6evg MULTI-COPPER OXIDASE
CUEO


(Ochrobactrum)
no annotation 4 ASP A 177
ASN A 226
ILE A 264
GLY A 288
None
0.89A 1meiA-6evgA:
undetectable
1meiA-6evgA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fgh BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2A


(Homo sapiens)
no annotation 4 SER A1855
SER A1854
GLY A1851
ARG A1846
None
0.97A 1meiA-6fghA:
undetectable
1meiA-6fghA:
9.13