SIMILAR PATTERNS OF AMINO ACIDS FOR 1MEI_A_MOAA600
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1eep | INOSINE5'-MONOPHOSPHATEDEHYDROGENASE (Borreliellaburgdorferi) |
PF00478(IMPDH) | 4 | ASP A 172SER A 173ASN A 201ILE A 223 | None | 0.59A | 1meiA-1eepA:44.3 | 1meiA-1eepA:33.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fwx | NITROUS OXIDEREDUCTASE (Paracoccusdenitrificans) |
PF13473(Cupredoxin_1) | 4 | SER A 138ASN A 139GLU A 87GLY A 88 | None | 0.66A | 1meiA-1fwxA:undetectable | 1meiA-1fwxA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpe | PROTEIN (GLUCOSEOXIDASE) (Penicilliumamagasakiense) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | SER A 107ASN A 111ILE A 110GLY A 32 | FAD A 600 (-3.4A)FAD A 600 (-3.9A)NoneFAD A 600 ( 4.6A) | 0.94A | 1meiA-1gpeA:undetectable | 1meiA-1gpeA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ia5 | POLYGALACTURONASE (Aspergillusaculeatus) |
PF00295(Glyco_hydro_28) | 4 | SER A 274SER A 275ASN A 269ILE A 240 | None | 1.00A | 1meiA-1ia5A:undetectable | 1meiA-1ia5A:21.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jcn | INOSINEMONOPHOSPHATEDEHYDROGENASE I (Homo sapiens) |
PF00478(IMPDH)PF00571(CBS) | 4 | ASP A 274SER A 275SER A 276ASN A 303 | NoneNoneNoneCPR A 631 ( 4.5A) | 0.30A | 1meiA-1jcnA:40.6 | 1meiA-1jcnA:35.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jeo | HYPOTHETICAL PROTEINMJ1247 (Methanocaldococcusjannaschii) |
PF01380(SIS) | 4 | SER A 11ASN A 13ILE A 14GLU A 6 | None | 0.96A | 1meiA-1jeoA:undetectable | 1meiA-1jeoA:16.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jr1 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 (Cricetulusgriseus) |
PF00478(IMPDH)PF00571(CBS) | 4 | ASP A 274SER A 275ASN A 303GLY A 415 | MOA A1332 (-3.5A)NoneMOA A1332 (-3.7A)IMP A1331 ( 3.1A) | 0.91A | 1meiA-1jr1A:48.3 | 1meiA-1jr1A:32.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jr1 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE 2 (Cricetulusgriseus) |
PF00478(IMPDH)PF00571(CBS) | 4 | ASP A 274SER A 276ASN A 303GLY A 415 | MOA A1332 (-3.5A)MOA A1332 (-2.6A)MOA A1332 (-3.7A)IMP A1331 ( 3.1A) | 0.40A | 1meiA-1jr1A:48.3 | 1meiA-1jr1A:32.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lo3 | IG GAMMA 2A HEAVYCHAIN (Mus musculus) |
no annotation | 4 | SER Y 25ASN Y 79ILE Y 80GLY Y 110 | None | 0.74A | 1meiA-1lo3Y:undetectable | 1meiA-1lo3Y:19.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) |
PF00478(IMPDH) | 7 | ASP A 261SER A 262SER A 263ASN A 291ILE A 313GLU A 408GLY A 409 | TAD A 901 (-2.3A)TAD A 901 ( 2.6A)TAD A 901 (-2.7A)IMP A 801 ( 4.6A)TAD A 901 (-4.1A)NoneIMP A 801 ( 3.2A) | 0.33A | 1meiA-1lrtA:58.5 | 1meiA-1lrtA:74.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1lrt | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) |
PF00478(IMPDH) | 4 | SER A 263ASN A 291GLU A 408GLY A 407 | TAD A 901 (-2.7A)IMP A 801 ( 4.6A)NoneIMP A 801 (-3.2A) | 0.91A | 1meiA-1lrtA:58.5 | 1meiA-1lrtA:74.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m1j | FIBRINOGEN BETACHAIN (Gallus gallus) |
PF00147(Fibrinogen_C)PF08702(Fib_alpha) | 4 | SER B 455ILE B 257GLU B 295GLY B 294 | None | 0.94A | 1meiA-1m1jB:undetectable | 1meiA-1m1jB:24.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mew | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) |
PF00478(IMPDH)PF00571(CBS) | 4 | ASP A 261GLU A 408GLY A 409ARG A 414 | NAD A 987 (-2.5A)NAD A 987 ( 4.9A)XMP A 602 ( 3.1A)None | 0.87A | 1meiA-1mewA:61.9 | 1meiA-1mewA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mew | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) |
PF00478(IMPDH)PF00571(CBS) | 7 | ASP A 261SER A 262SER A 263ASN A 291ILE A 313GLU A 408GLY A 409 | NAD A 987 (-2.5A)NAD A 987 (-2.7A)NAD A 987 (-3.1A)XMP A 602 ( 4.4A)NAD A 987 (-4.5A)NAD A 987 ( 4.9A)XMP A 602 ( 3.1A) | 0.27A | 1meiA-1mewA:61.9 | 1meiA-1mewA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1mew | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Tritrichomonassuis) |
PF00478(IMPDH)PF00571(CBS) | 4 | SER A 263ASN A 291GLU A 408GLY A 407 | NAD A 987 (-3.1A)XMP A 602 ( 4.4A)NAD A 987 ( 4.9A)XMP A 602 (-3.3A) | 0.83A | 1meiA-1mewA:61.9 | 1meiA-1mewA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mox | EPIDERMAL GROWTHFACTOR RECEPTOR (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain) | 4 | SER A 326ASN A 328ILE A 332GLY A 315 | NoneNAG A 650 (-1.9A)NoneNone | 0.81A | 1meiA-1moxA:undetectable | 1meiA-1moxA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o60 | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Haemophilusinfluenzae) |
PF00793(DAHP_synth_1) | 4 | ASP A 199ASN A 136ILE A 111GLY A 24 | None | 0.98A | 1meiA-1o60A:12.1 | 1meiA-1o60A:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wf3 | GTP-BINDING PROTEIN (Thermusthermophilus) |
PF01926(MMR_HSR1)PF07650(KH_2) | 4 | SER A 7ILE A 49GLY A 53ARG A 54 | None | 0.83A | 1meiA-1wf3A:undetectable | 1meiA-1wf3A:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wn1 | DIPEPTIDASE (Pyrococcushorikoshii) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 4 | ASP A 105ILE A 43GLU A 39GLY A 38 | None | 0.88A | 1meiA-1wn1A:undetectable | 1meiA-1wn1A:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xz9 | AFADIN (Homo sapiens) |
PF00595(PDZ) | 4 | SER A 44SER A 26ILE A 27GLY A 49 | None | 1.00A | 1meiA-1xz9A:undetectable | 1meiA-1xz9A:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yf2 | TYPE IRESTRICTION-MODIFICATION ENZYME, SSUBUNIT (Methanocaldococcusjannaschii) |
PF01420(Methylase_S) | 4 | ASP A 265ASN A 259ILE A 258GLU A 279 | None | 0.79A | 1meiA-1yf2A:undetectable | 1meiA-1yf2A:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2atm | HYALURONOGLUCOSAMINIDASE (Vespulavulgaris) |
PF01630(Glyco_hydro_56) | 4 | SER A 248ASN A 250ILE A 247GLY A 289 | None | 0.95A | 1meiA-2atmA:5.3 | 1meiA-2atmA:19.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2cu0 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Pyrococcushorikoshii) |
PF00478(IMPDH)PF00571(CBS) | 4 | ASP A 247ASN A 275ILE A 295GLY A 385 | NoneXMP A1001 ( 4.4A)NoneXMP A1001 (-3.1A) | 0.44A | 1meiA-2cu0A:47.5 | 1meiA-2cu0A:33.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0v | METHANOLDEHYDROGENASE LARGESUBUNIT (Hyphomicrobiumdenitrificans) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | SER A 69SER A 70ASN A 108GLY A 536 | None | 0.81A | 1meiA-2d0vA:undetectable | 1meiA-2d0vA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7u | ADENYLOSUCCINATESYNTHETASE (Pyrococcushorikoshii) |
PF00709(Adenylsucc_synt) | 4 | SER A 223ILE A 323GLU A 14GLY A 15 | None | 0.87A | 1meiA-2d7uA:undetectable | 1meiA-2d7uA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hal | HEPATITIS A PROTEASE3C (Hepatovirus A) |
PF00548(Peptidase_C3) | 4 | SER A 178SER A 179GLU A 132GLY A 133 | None | 0.68A | 1meiA-2halA:undetectable | 1meiA-2halA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p9b | POSSIBLE PROLIDASE (Bifidobacteriumlongum) |
PF01979(Amidohydro_1) | 4 | SER A 225ILE A 168GLU A 251GLY A 252 | None | 0.95A | 1meiA-2p9bA:5.2 | 1meiA-2p9bA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qj8 | MLR6093 PROTEIN (Mesorhizobiumjaponicum) |
PF04952(AstE_AspA) | 4 | ASN A 87ILE A 86GLU A 119GLY A 111 | None | 0.96A | 1meiA-2qj8A:undetectable | 1meiA-2qj8A:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z61 | PROBABLE ASPARTATEAMINOTRANSFERASE 2 (Methanocaldococcusjannaschii) |
PF00155(Aminotran_1_2) | 4 | SER A 236ASN A 91ILE A 241GLU A 212 | None | 0.72A | 1meiA-2z61A:undetectable | 1meiA-2z61A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zws | NEUTRAL CERAMIDASE (Pseudomonasaeruginosa) |
PF04734(Ceramidase_alk)PF17048(Ceramidse_alk_C) | 4 | SER A 464ILE A 326GLU A 459ARG A 160 | NoneNoneNone ZN A 647 ( 4.3A) | 0.87A | 1meiA-2zwsA:undetectable | 1meiA-2zwsA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aat | ASPARTATEAMINOTRANSFERASE (Escherichiacoli) |
PF00155(Aminotran_1_2) | 4 | SER A 255SER A 257ASN A 259GLY A 302 | PLP A 410 (-2.4A)PLP A 410 (-3.2A)NoneNone | 0.99A | 1meiA-3aatA:undetectable | 1meiA-3aatA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clh | 3-DEHYDROQUINATESYNTHASE (Helicobacterpylori) |
PF01761(DHQ_synthase) | 4 | SER A 206ASN A 208ILE A 209GLU A 201 | None | 0.90A | 1meiA-3clhA:2.5 | 1meiA-3clhA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ekg | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Azotobactervinelandii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ASN A 125ILE A 124GLU A 270GLY A 269 | NoneNone MG A 601 ( 2.4A)None | 0.69A | 1meiA-3ekgA:10.3 | 1meiA-3ekgA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3faw | RETICULOCYTE BINDINGPROTEIN (Streptococcusagalactiae) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 4 | ASP A1079ASN A1099ILE A1148GLY A1073 | None | 0.75A | 1meiA-3fawA:undetectable | 1meiA-3fawA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3htn | PUTATIVE DNA BINDINGPROTEIN (Bacteroidesthetaiotaomicron) |
PF03479(DUF296) | 4 | SER A 81ASN A 120ILE A 121GLY A 84 | None | 0.96A | 1meiA-3htnA:undetectable | 1meiA-3htnA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ing | HOMOSERINEDEHYDROGENASE (Thermoplasmaacidophilum) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 4 | SER A 171SER A 172ASN A 175GLY A 146 | NoneNoneNoneNDP A 326 (-3.9A) | 1.01A | 1meiA-3ingA:undetectable | 1meiA-3ingA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4j | TRANSLATIONINITIATION FACTORIF-2 (Thermusthermophilus) |
PF00009(GTP_EFTU)PF04760(IF2_N)PF11987(IF-2) | 4 | SER A 254ASN A 265ILE A 251GLY A 410 | None | 0.80A | 1meiA-3j4jA:undetectable | 1meiA-3j4jA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4u | MAJOR CAPSID PROTEIN (Bordetellavirus BPP1) |
no annotation | 4 | SER A 136SER A 135GLY A 144ARG A 148 | None | 0.93A | 1meiA-3j4uA:undetectable | 1meiA-3j4uA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3juj | UDP-GLUCOSEPYROPHOSPHORYLASE(GALU) (Helicobacterpylori) |
PF00483(NTP_transferase) | 4 | SER A 87ASN A 90ILE A 91ARG A 272 | None | 0.86A | 1meiA-3jujA:undetectable | 1meiA-3jujA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ku0 | RIBOSOME-INACTIVATING PROTEIN GELONIN (Suregadamultiflora) |
PF00161(RIP) | 4 | SER A 34ASN A 33ILE A 37GLY A 209 | None | 0.99A | 1meiA-3ku0A:undetectable | 1meiA-3ku0A:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nf4 | ACYL-COADEHYDROGENASE (Mycolicibacteriumthermoresistibile) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | SER A 321ILE A 322GLU A 367GLY A 368 | NoneNoneNoneFAD A 384 ( 4.4A) | 0.84A | 1meiA-3nf4A:undetectable | 1meiA-3nf4A:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3njp | EPIDERMAL GROWTHFACTOR RECEPTOR (Homo sapiens) |
PF00757(Furin-like)PF01030(Recep_L_domain)PF14843(GF_recep_IV) | 4 | SER A 326ASN A 328ILE A 332GLY A 315 | NoneNAG A1328 (-1.7A)NoneNone | 0.86A | 1meiA-3njpA:undetectable | 1meiA-3njpA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o5c | CYTOCHROME C551PEROXIDASE (Shewanellaoneidensis) |
PF00034(Cytochrom_C)PF03150(CCP_MauG) | 4 | ASP A 72ASN A 88ILE A 87GLY A 79 | None CA A 601 (-2.9A)HEM A 401 (-4.4A)HEM A 401 ( 3.8A) | 1.01A | 1meiA-3o5cA:undetectable | 1meiA-3o5cA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oz7 | PHOSPHOGLYCERATEKINASE (Plasmodiumfalciparum) |
PF00162(PGK) | 4 | SER A 185ASN A 162ILE A 161GLU A 192 | None | 1.00A | 1meiA-3oz7A:undetectable | 1meiA-3oz7A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sdq | ALPHA-BISABOLENESYNTHASE (Abies grandis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | SER A 729SER A 730GLU A 644GLY A 663 | None | 0.95A | 1meiA-3sdqA:undetectable | 1meiA-3sdqA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sl1 | ARGINASE (Plasmodiumfalciparum) |
PF00491(Arginase) | 4 | ASP A 325SER A 326ILE A 291GLY A 219 | MN A 412 ( 2.0A)NoneNoneNone | 0.73A | 1meiA-3sl1A:undetectable | 1meiA-3sl1A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3suc | PRENECK APPENDAGEPROTEIN (Bacillus virusphi29) |
PF11962(Peptidase_G2)PF12708(Pectate_lyase_3) | 4 | SER A 491ASN A 519ILE A 518GLY A 468 | None | 0.68A | 1meiA-3sucA:undetectable | 1meiA-3sucA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tix | CHROMODOMAIN-CONTAININGPROTEIN 1UBIQUITIN-LIKEPROTEINSMT3,RNA-INDUCEDTRANSCRIPTIONALSILENCING COMPLEXPROTEIN TAS3 (Saccharomycescerevisiae;Schizosaccharomycespombe) |
PF11976(Rad60-SLD)no annotation | 4 | SER B 706ASN B 744GLU A 63GLY A -33 | None | 0.92A | 1meiA-3tixB:undetectable | 1meiA-3tixB:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w08 | ALDOXIME DEHYDRATASE (Pseudomonaschlororaphis) |
PF13816(Dehydratase_hem) | 4 | SER A 3ILE A 166GLU A 21ARG A 13 | None | 0.92A | 1meiA-3w08A:undetectable | 1meiA-3w08A:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wsv | L-LACTATEDEHYDROGENASE (Enterococcusmundtii) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | SER A 122ASN A 98ILE A 101GLY A 14 | None | 0.98A | 1meiA-3wsvA:undetectable | 1meiA-3wsvA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a0s | OCTENOYL-COAREDUCTASE/CARBOXYLASE (Streptomycescinnabarigriseus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | SER A 72SER A 73ILE A 74GLU A 194 | None | 0.91A | 1meiA-4a0sA:undetectable | 1meiA-4a0sA:19.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4af0 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Cryptococcusneoformans) |
PF00478(IMPDH)PF00571(CBS) | 5 | ASP B 288SER B 289SER B 290ASN B 317GLY B 429 | MOA B1526 (-3.3A)MOA B1526 (-3.9A)MOA B1526 (-2.6A)MOA B1526 ( 3.6A)IMP B1527 ( 3.3A) | 0.32A | 1meiA-4af0B:48.1 | 1meiA-4af0B:33.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dwq | TRNA-SPLICING LIGASERTCB (Pyrococcushorikoshii) |
PF01139(RtcB) | 4 | SER A 88SER A 270ILE A 256GLY A 85 | None | 0.67A | 1meiA-4dwqA:undetectable | 1meiA-4dwqA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwt | ELONGATION FACTORTS, ELONGATIONFACTOR TU, LINKER, QBETA REPLICASE (Escherichiacoli;Escherichiavirus Qbeta) |
PF00009(GTP_EFTU)PF00889(EF_TS)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2)PF03431(RNA_replicase_B) | 4 | ASP A 621ILE A 532GLY A 624ARG A 612 | None | 0.94A | 1meiA-4fwtA:undetectable | 1meiA-4fwtA:17.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4fxs | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Vibrio cholerae) |
PF00478(IMPDH)PF00571(CBS) | 5 | SER A 251SER A 252ASN A 279ILE A 301GLY A 391 | MOA A 702 (-3.7A)MOA A 702 (-2.8A)MOA A 702 (-3.5A)MOA A 702 (-4.1A)IMP A 701 (-3.2A) | 0.47A | 1meiA-4fxsA:49.7 | 1meiA-4fxsA:36.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hfu | FAB 8M2 HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | SER H 30ILE H 51GLU H 98GLY H 97 | None | 0.96A | 1meiA-4hfuH:undetectable | 1meiA-4hfuH:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i5j | SERINE/THREONINE-PROTEIN PHOSPHATASE 2AREGULATORY SUBUNITB'' SUBUNIT ALPHA (Homo sapiens) |
PF13499(EF-hand_7) | 4 | ASP A 196ILE A 249GLU A 193GLY A 242 | None | 0.83A | 1meiA-4i5jA:undetectable | 1meiA-4i5jA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i9u | L-LACTATEDEHYDROGENASE ACHAIN (Oryctolaguscuniculus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | SER A 136ASN A 112ILE A 115GLY A 28 | NoneNone1E7 A 401 (-4.2A)None | 1.01A | 1meiA-4i9uA:undetectable | 1meiA-4i9uA:21.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ix2 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Vibrio cholerae) |
PF00478(IMPDH) | 5 | ASP A 250SER A 251SER A 252ASN A 279ILE A 301 | NoneNoneNoneIMP A 501 ( 4.4A)None | 0.83A | 1meiA-4ix2A:45.5 | 1meiA-4ix2A:31.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ixo | NIFS-LIKE PROTEIN (Rickettsiaafricae) |
PF00266(Aminotran_5) | 4 | SER A 348ASN A 287ILE A 258GLY A 198 | None | 0.88A | 1meiA-4ixoA:undetectable | 1meiA-4ixoA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lu0 | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Pseudomonasaeruginosa) |
PF00793(DAHP_synth_1) | 4 | ASP A 203ASN A 142ILE A 117GLY A 30 | None | 0.94A | 1meiA-4lu0A:12.1 | 1meiA-4lu0A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mz1 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Campylobacterjejuni) |
PF00478(IMPDH) | 4 | ASP A 244SER A 245ILE A 295GLY A 385 | NoneNoneNoneIMP A 500 ( 3.3A) | 0.87A | 1meiA-4mz1A:49.7 | 1meiA-4mz1A:29.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mz1 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Campylobacterjejuni) |
PF00478(IMPDH) | 4 | SER A 245ASN A 273ILE A 295GLY A 385 | NoneIMP A 500 ( 4.1A)NoneIMP A 500 ( 3.3A) | 0.53A | 1meiA-4mz1A:49.7 | 1meiA-4mz1A:29.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n9g | ANTIBODY 17HD9,HEAVY CHAIN (Macaca mulatta) |
PF07654(C1-set)PF07686(V-set) | 4 | ASN A 60ILE A 48GLY A 100ARG A 100 | None | 0.96A | 1meiA-4n9gA:undetectable | 1meiA-4n9gA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nk6 | POLY(BETA-D-MANNURONATE) C5 EPIMERASE (Pseudomonassyringae groupgenomosp. 3) |
PF13229(Beta_helix) | 4 | ASP A 331SER A 357ILE A 381GLY A 334 | MLY A 356 ( 3.7A)MLY A 356 ( 4.5A)NoneNone | 0.83A | 1meiA-4nk6A:undetectable | 1meiA-4nk6A:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nru | RNA DEPENDENT RNAPOLYMERASE (Norwalk virus) |
PF00680(RdRP_1) | 4 | SER A 71ILE A 292GLU A 296GLY A 297 | None | 0.92A | 1meiA-4nruA:undetectable | 1meiA-4nruA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ogc | HNH ENDONUCLEASEDOMAIN PROTEIN (Actinomycesnaeslundii) |
PF01844(HNH) | 4 | SER A1005ASN A1002ILE A1001GLY A1012 | None | 0.91A | 1meiA-4ogcA:undetectable | 1meiA-4ogcA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ozy | POLY(BETA-D-MANNURONATE) C5 EPIMERASE (Pseudomonassyringae groupgenomosp. 3) |
PF13229(Beta_helix) | 4 | ASP A 331SER A 357ILE A 381GLY A 334 | MLY A 356 ( 3.5A)MLY A 356 ( 4.6A)NoneNone | 0.80A | 1meiA-4ozyA:undetectable | 1meiA-4ozyA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppz | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Neisseriameningitidis) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | ASP A 70SER A 133ILE A 52GLU A 135 | NoneNoneNone ZN A 601 (-3.9A) | 0.96A | 1meiA-4ppzA:undetectable | 1meiA-4ppzA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6u | UNCHARACTERIZEDPROTEIN (Mycobacteriumtuberculosis) |
no annotation | 4 | SER A 122ILE A 179GLU A 117GLY A 101 | 1PE A 401 (-3.2A)NoneNoneNone | 0.97A | 1meiA-4q6uA:undetectable | 1meiA-4q6uA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qa9 | EPOXIDE HYDROLASE (Streptomycescarzinostaticus) |
PF06441(EHN) | 4 | ASP A 346SER A 204ASN A 202ILE A 316 | EDO A 405 (-3.2A)NoneEDO A 405 (-4.7A)None | 0.88A | 1meiA-4qa9A:undetectable | 1meiA-4qa9A:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u8t | ZYRO0G01672P (Zygosaccharomycesrouxii) |
PF04146(YTH) | 4 | SER A 194ASN A 197ILE A 199GLU A 189 | None | 0.94A | 1meiA-4u8tA:undetectable | 1meiA-4u8tA:15.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wa0 | POSSIBLE ADHESIN (Caldicellulosiruptorkronotskyensis) |
no annotation | 4 | ASP A 473SER A 477ILE A 508GLY A 497 | MG A 601 (-3.3A)NoneNoneNone | 0.62A | 1meiA-4wa0A:undetectable | 1meiA-4wa0A:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wj3 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT A (Pseudomonasaeruginosa) |
PF01425(Amidase) | 4 | ASP A 209ILE A 310GLY A 175ARG A 178 | None | 0.94A | 1meiA-4wj3A:undetectable | 1meiA-4wj3A:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wpg | DTDP-4-DEHYDRORHAMNOSE REDUCTASE (Streptococcuspyogenes) |
PF04321(RmlD_sub_bind) | 4 | SER A 82ASN A 84ILE A 36GLU A 75 | None | 0.97A | 1meiA-4wpgA:undetectable | 1meiA-4wpgA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xhb | SIALIDASE B (Streptococcuspneumoniae) |
PF02012(BNR)PF02973(Sialidase)PF13088(BNR_2) | 4 | SER A 91ILE A 183GLU A 194GLY A 195 | None | 0.93A | 1meiA-4xhbA:undetectable | 1meiA-4xhbA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwu | INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE,INOSINE-5'-MONOPHOSPHATEDEHYDROGENASE (Eremotheciumgossypii) |
PF00478(IMPDH) | 4 | ASP A 277SER A 278SER A 279ASN A 306 | None | 0.22A | 1meiA-4xwuA:38.9 | 1meiA-4xwuA:28.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z61 | PHYTOSULFOKINERECEPTOR 1 (Daucus carota) |
PF00560(LRR_1)PF13855(LRR_8) | 4 | SER A 143SER A 142ASN A 167GLY A 94 | NoneNoneNoneNAG A 701 ( 3.7A) | 0.98A | 1meiA-4z61A:undetectable | 1meiA-4z61A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b1h | CYSTATHIONINEBETA-SYNTHASE (Lactobacillusplantarum) |
PF00291(PALP) | 4 | ASP A 290SER A 291SER A 292GLY A 265 | LLP A 42 ( 3.2A)NoneNoneNone | 0.83A | 1meiA-5b1hA:undetectable | 1meiA-5b1hA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gr8 | LEUCINE-RICH REPEATRECEPTOR-LIKEPROTEIN KINASE PEPR1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 4 | SER A 422ASN A 445GLU A 378GLY A 377 | None | 0.93A | 1meiA-5gr8A:undetectable | 1meiA-5gr8A:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1k | GEM-ASSOCIATEDPROTEIN 5 (Homo sapiens) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 4 | SER A 604ASN A 605GLU A 541GLY A 554 | None A C 10 ( 3.7A)NoneNone | 0.92A | 1meiA-5h1kA:undetectable | 1meiA-5h1kA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ie9 | NUCLEOTIDEPYROPHOSPHOHYDROLASE (Bacillus cereus) |
PF03819(MazG) | 4 | ASP A 14SER A 80ASN A 82GLY A 23 | None | 0.92A | 1meiA-5ie9A:undetectable | 1meiA-5ie9A:10.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j72 | PUTATIVEN-ACETYLMURAMOYL-L-ALANINEAMIDASE,AUTOLYSINCWP6 (Clostridioidesdifficile) |
PF01520(Amidase_3)PF04122(CW_binding_2) | 4 | ASP A 249ILE A 180GLU A 252GLY A 246 | None | 0.94A | 1meiA-5j72A:undetectable | 1meiA-5j72A:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jjp | NONRIBOSOMAL PEPTIDESYNTHASE (Streptomycessp. MJ635-86F5) |
PF00501(AMP-binding) | 4 | SER A 184ASN A 188ILE A 189GLY A 92 | None | 1.00A | 1meiA-5jjpA:undetectable | 1meiA-5jjpA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jwf | ASP/GLU-SPECIFICDIPEPTIDYL-PEPTIDASE (Porphyromonasgingivalis) |
PF10459(Peptidase_S46) | 4 | ILE A 345GLU A 676GLY A 677ARG A 673 | None | 0.96A | 1meiA-5jwfA:undetectable | 1meiA-5jwfA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxk | ASP/GLU-SPECIFICDIPEPTIDYL-PEPTIDASE (Porphyromonasendodontalis) |
PF10459(Peptidase_S46) | 4 | ILE A 344GLU A 673GLY A 674ARG A 670 | None | 0.88A | 1meiA-5jxkA:undetectable | 1meiA-5jxkA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jz8 | ASPARTYL/ASPARAGINYLBETA-HYDROXYLASE (Homo sapiens) |
PF05118(Asp_Arg_Hydrox)PF13181(TPR_8)PF13432(TPR_16) | 4 | ASP A 721SER A 722SER A 563ARG A 662 | OGA A 802 ( 4.8A)NoneNoneNone | 0.95A | 1meiA-5jz8A:undetectable | 1meiA-5jz8A:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ko5 | PURINE NUCLEOSIDEPHOSPHORYLASE (Schistosomamansoni) |
PF01048(PNP_UDP_1) | 4 | SER A 241ILE A 243GLY A 34ARG A 86 | NoneNoneEDO A 302 (-3.4A)EDO A 302 (-4.3A) | 0.97A | 1meiA-5ko5A:undetectable | 1meiA-5ko5A:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks8 | PYRUVATE CARBOXYLASESUBUNIT ALPHA (Methylobacillusflagellatus) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | ILE A 354GLU A 12GLY A 11ARG A 10 | None | 0.97A | 1meiA-5ks8A:undetectable | 1meiA-5ks8A:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l39 | RMM MICROCOMPARTMENTSHELL PROTEINMSM0275 (Mycolicibacteriumsmegmatis) |
PF00936(BMC) | 4 | SER A 147ILE A 150GLU A 68GLY A 72 | None | 0.94A | 1meiA-5l39A:undetectable | 1meiA-5l39A:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqm | GLYCOSYL HYDROLASESFAMILY 2, SUGARBINDING DOMAIN (Bacteroidesthetaiotaomicron) |
PF17132(Glyco_hydro_106) | 4 | ASP A 547SER A 696ILE A 697GLY A 581 | None | 0.96A | 1meiA-5mqmA:3.7 | 1meiA-5mqmA:19.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5tc3 | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE (Eremotheciumgossypii) |
PF00478(IMPDH)PF00571(CBS) | 5 | ASP A 277SER A 278SER A 279ASN A 306GLY A 418 | NoneNoneNone5GP A 600 (-3.2A)5GP A 600 (-3.1A) | 0.58A | 1meiA-5tc3A:46.0 | 1meiA-5tc3A:34.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7a | ACYLOXYACYLHYDROLASE LARGESUBUNIT (Oryctolaguscuniculus) |
no annotation | 4 | ASP B 296ASN B 335ILE B 336GLY B 340 | NoneNoneNoneFTT B 609 ( 3.3A) | 0.88A | 1meiA-5w7aB:undetectable | 1meiA-5w7aB:11.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7c | ACYLOXYACYLHYDROLASE (Homo sapiens) |
no annotation | 4 | ASP C 297ASN C 336ILE C 337GLY C 341 | NoneNoneNoneFTT C 610 ( 3.1A) | 0.87A | 1meiA-5w7cC:undetectable | 1meiA-5w7cC:10.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yww | NUCLEOTIDE BINDINGPROTEIN PINC (Sulfolobusislandicus) |
no annotation | 4 | ASP A 373ILE A 253GLU A 249GLY A 342 | None | 0.91A | 1meiA-5ywwA:undetectable | 1meiA-5ywwA:10.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bng | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATEALDOLASE (Acinetobacterbaumannii) |
no annotation | 4 | ASP A 201ASN A 140ILE A 115GLY A 28 | None | 0.99A | 1meiA-6bngA:7.3 | 1meiA-6bngA:9.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c90 | EXOSOME RNA HELICASEMTR4,EXOSOME RNAHELICASE MTR4 (Homo sapiens) |
no annotation | 4 | SER A 513SER A 514ILE A 518GLY A 548 | None | 0.95A | 1meiA-6c90A:undetectable | 1meiA-6c90A:11.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6caj | TRANSLATIONINITIATION FACTOREIF-2B SUBUNIT BETA (Homo sapiens) |
no annotation | 4 | ASP C 219ILE C 234GLU C 193GLY C 200 | None | 0.84A | 1meiA-6cajC:undetectable | 1meiA-6cajC:9.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6evg | MULTI-COPPER OXIDASECUEO (Ochrobactrum) |
no annotation | 4 | ASP A 177ASN A 226ILE A 264GLY A 288 | None | 0.89A | 1meiA-6evgA:undetectable | 1meiA-6evgA:10.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fgh | BROMODOMAIN ADJACENTTO ZINC FINGERDOMAIN PROTEIN 2A (Homo sapiens) |
no annotation | 4 | SER A1855SER A1854GLY A1851ARG A1846 | None | 0.97A | 1meiA-6fghA:undetectable | 1meiA-6fghA:9.13 |